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| Product | Description | |
|---|---|---|
| Gly-Tyr-Gly-OH | Synonyms: Glycyl-L-tyrosyl glycine. Grades: ≥ 95% (HPLC). CAS No. 6099-8-7. Molecular formula: C13H17N3O5. Mole weight: 295.3. |  |
| Gly-Tyr-Gly-OH ≥95% (HPLC) | Gly-Tyr-Gly-OH ≥95% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences. |  Worldwide |
| Gly-Tyr-OH | Synonyms: Glycyl-L-tyrosine. Grades: ≥ 99% (Assay, on anhydrous basis). CAS No. 658-79-7. Molecular formula: C11H14N2O4. Mole weight: 238.24. | |
| Gly-Tyr-OH ≥98.5% | Gly-Tyr-OH ≥98.5%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 658-79-7. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences. | Worldwide |
| Gly-Val | Gly-Val is a substrate for dipeptide hydrolase activities in rat intestinal mucosa. Synonyms: Glycyl-L-valine; Glycylvaline; L-Valine, N-glycyl-; GV dipeptide; (S)-2-(2-Aminoacetamido)-3-methylbutanoic acid. CAS No. 1963-21-9. Molecular formula: C7H14N2O3. Mole weight: 174.20. | |
| Gly-Val-OH HCl | Synonyms: Glycyl-L-valine hydrochloride. Grades: ≥ 98%. Molecular formula: C7H14N2O3·HCl. Mole weight: 210.7. | |
| Gly-Val-OH·HCl 99+% (HPLC) | Gly-Val-OH·HCl 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences. | Worldwide |
| GLYX 13 | GLYX 13. Group: Biochemicals. Grades: Purified. CAS No. 117928-94-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Gly-Xaa carboxypeptidase | From yeast. In peptidase family M20 (glutamate carboxypeptidase family). Group: Enzymes. Synonyms: glycine carboxypeptidase; carboxypeptidase a; carboxypeptidase S; peptidase α; yeast carboxypeptidase; Gly-X carboxypeptidase. Enzyme Commission Number: EC 3.4.17.4. CAS No. 9025-25-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4078; Gly-Xaa carboxypeptidase; EC 3.4.17.4; 9025-25-6; glycine carboxypeptidase; carboxypeptidase a; carboxypeptidase S; peptidase α; yeast carboxypeptidase; Gly-X carboxypeptidase. Cat No: EXWM-4078. |  |
| GM 1489 | GM 1489 is a potent broad-spectrum inhibitor of matrix metalloproteinases (MMPs) with Ki values of 0.002, 0.1, 0.5, 0.2, and 20 μM for MMP-1, MMP-8, MMP-2, MMP-9, and MMP-3, respectively. Synonyms: Hexanoic acid, 3- [ [ [ (1S) -1- (1H-indol-3-ylmethyl) -2-oxo-2- [ [ (1S) -1-phenylethyl] amino] ethyl] amino] carbonyl] -5-methyl-, (3R)-; (3R) -3- [ [ [ (1S) -1- (1H-Indol-3-ylmethyl) -2-oxo-2- [ [ (1S) -1-phenylethyl] amino] ethyl] amino] carbonyl] -5-methylhexanoic acid; Hexanoic acid, 3-[[[1- (1H-indol-3-ylmethyl) -2-oxo-2-[ (1-phenylethyl) amino]ethyl]amino]carbonyl]-5-methyl-, [3R-[3R*[S*(S*)]]]-; GM-1489; GM1489. Grades: ≥98%. CAS No. 171347-75-4. Molecular formula: C27H33N3O4. Mole weight: 463.57. | |
| GM1a-Oligosaccharide | GM1a-Oligosaccharide is a cutting-edge compound designated for research in neurodegenerative maladies, namely the formidable Parkinson's disease and Alzheimer's disease. Its pronounced efficacy stems from its remarkable capacity to augment the physiological process of neuronal regeneration while concurrently proactively mitigating neuronal cell mortality. Synonyms: Galb1-3GalNAcb1-4(Neu5Aca2-3)Galb1-4Glc. Molecular formula: C37H61N2O29Na. Mole weight: 1020.87. | |
| GM1b-Oligosaccharide | GM1b-Oligosaccharide is an innovative and promising compound, showcasing its potential in studying complex neurodegenerative ailments including Parkinson's and Alzheimer's diseases. Derived from the GM1 ganglioside, this compound offers a remarkable neuroprotective effect by significantly augmenting neuronal survival and effectively thwarting cognitive decline. Molecular formula: C37H61N2O29Na. Mole weight: 1020.87. | |
| GM1-Ganglioside labelled by biotin | GM1-Ganglioside labelled by biotin is a crucial tool for studying neurodegenerative diseases such as Alzheimer's and Parkinson's. This specialized probe facilitates the detection and visualization of GM1-Ganglioside within cells and tissues. Its biotin label enables specific binding to avidin or streptavidin is allowing for further investigation of the role of GM1-Ganglioside in these diseases. Synonyms: N-Hexanoyl-biotin-monosialoganglioside GM1. Molecular formula: C71H122N6O33S. Mole weight: 1619.82. | |
| GM1-Lysoganglioside | GM1-Lysoganglioside is a biomedicine utilized in the treatment of neurodegenerative disorders and nerve injuries. It acts as an essential neurotrophic factor in promoting nerve regeneration and maintaining neuronal survival. GM1-Lysoganglioside has shown promising results in alleviating symptoms associated with diseases like Alzheimer's and Parkinson's, making it a potential therapeutic option for these conditions. Synonyms: lyso-Monosialoganglioside GM1. CAS No. 171483-40-2. Molecular formula: C55H97N3O30 xNa. Mole weight: 1280.36 (free acid). | |
| GM1-Lysoganglioside sodium | GM1-Lysoganglioside sodium, a highly esteemed biomedical agent, stands as a fostering solution amidst the intricate realm of neurodegenerative afflictions like Parkinson's disease and Alzheimer's disease. Synonyms: lyso-Monosialoganglioside GM1; Lyso-GM1. Grades: 95%. CAS No. 94458-59-0. Molecular formula: C55H97N3O30·xNa. Mole weight: 1280.36 (free acid). | |
| GM1-Pentasaccharide | GM1-Pentasaccharide, an auspicious compound in the field of biomedicine, holds substantial promise for the management of neurodegenerative ailments. Originating from the ganglioside GM1, this pentasaccharide exhibits remarkable prowess in augmenting neuronal rejuvenation and restoring impaired nerves. By virtue of its neuroprotective attributes, it manifests as an invaluable therapeutic asset for afflictions including Alzheimer's and Parkinson's disease. Synonyms: GM1-oligosaccharide. CAS No. 52659-37-7. Molecular formula: C37H62N2O29. Mole weight: 998.88. | |
| GM1-Pentasaccharide, APD-HSA conjugate | | |
| GM1-Pentasaccharide labelled by biotin | GM1-Pentasaccharide labelled by biotin is a biotin-labelled compound widely utilized in the biomedical industry for extensive research purposes. Its application predominantly revolves around comprehending the intricate interplay between GM1-Pentasaccharide and specific biomolecules. It facilitates effortless detection and observation via biotin-streptavidin labeling methods. Synonyms: GM1-Pentasaccharide-O(CH2)3NHCO(CH2)5NH-biotin. Molecular formula: C50H83N5O31S. Mole weight: 1282.28. | |
| GM2-Ganglioside | GM2-Ganglioside, a lipid molecule nestled in cellular membranes, has been linked to various pathologies of the central nervous system like Huntington's and Parkinson's disease. By delving into the underlying pathogenesis pathways, GM2-Ganglioside can serve as a potent therapeutic agent. As a clinical ingredient for vaccines against infectious diseases and a potential player in cancer therapy, this nano-molecule is showing promise as a versatile therapeutic option. Synonyms: Monosialoganglioside GM2; b-GalNAc-(1?4)-[a-Neu5Ac-(2?3)]-b-Gal(1?4)-b-Glc-(1?1)-Cer. CAS No. 19600-01-2. Molecular formula: C67H121N3O26.xNa. Mole weight: 1384.68 (free acid). | |
| GM2-Oligosaccharide | GM2-Oligosaccharide is a prominent constituent in the realm of biomedical applications, finding extensive utility in the investigation of lysosomal storage disorders. Acting as an invaluable compoundin the scientific domain, this oligosaccharide facilitates the exploration of intricate processes underlying GM2 ganglioside metabolism. Molecular formula: C31H51N2O24Na. Mole weight: 858.73. | |
| GM2-Oligosaccharide-spacer-NH2 ammonium | GM2-Oligosaccharide-spacer-NH2 ammonium is a vital compound used in biomedicine. Its application lies in the treatment of GM2 gangliosidoses, a group of genetic disorders caused by the deficiency of vital enzymes. Synonyms: GalNAcb-4(NeuAca2-3)Galb-4Glcb-NAc-spacer-NH2. Molecular formula: C44H75N7O27·NH3. Mole weight: 1151.13. | |
| GM2-Oligosaccharide-sp-biotin | | |
| GM3-Ganglioside | GM3-Ganglioside, a renowned biomedical compound, is an exceptional therapeutic agent employed for managing debilitating neurodegenerative conditions, prominently encompassing Alzheimer's disease and Parkinson's disease. Its inherent proficiency in preserving neuronal coherence and functionality renders it indispensable in clinical practice. Synonyms: aNeu5Ac(2-3)bDGalp(1-4)bDGlcp(1-1)Cer. CAS No. 54827-14-4. Molecular formula: C59H111N3O21 xNa. Mole weight: 1198.52 (free acid basis). | |
| GM3-Ganglioside labelled by NBD | GM3-Ganglioside labelled by NBD is a specialized GM3-Ganglioside molecule, known for its facile integration with NBD fluorescent probe. Its wide-ranging application encompasses unfathomable diseases, including cancer and neurodegenerative disorders. Synonyms: N-Acetyl-a-D-neuraminic acid)-(2->3)-O-b-D-galactopyranosyl-(1->4)-O-b-D-glucopyranosyl-(1->1)-(2S,3R,4E)-2-N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)aminooctanamido-4-octadecene-1,3-diol ammonium salt; aNeu5Ac(2-3)bDGalp(1-4)bDGlcp(1-1)Cer linked 7-nitrobenz-2-oxa-1,3-diazole. Molecular formula: C55H90N6O24 H3N. Mole weight: 1236.36. | |
| GM3-Ganglioside labelled by NBD ammonium | GM3-Ganglioside labelled by NBD ammonium is a vital tool in the biomedical industry used for researching and diagnosing various diseases. This product plays a crucial role in studying and understanding the targeting and metabolism of GM3-Ganglioside, a glycosphingolipid involved in neurological disorders and cancer progression. Its NBD ammonium label allows for fluorescence-based detection and visualization in biological systems, enabling accurate analysis and potential therapeutic advancements. Synonyms: N-Acetyl-a-D-neuraminic acid)-(2->3)-O-b-D-galactopyranosyl-(1->4)-O-b-D-glucopyranosyl-(1->1)-(2S,3R,4E)-2-N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)aminooctanamido-4-octadecene-1,3-diol ammonium salt; aNeu5Ac(2-3)bDGalp(1-4)bDGlcp(1-1)Cer linked 7-nitrobenz-2-oxa-1,3-diazole. Grades: 95%. Molecular formula: C55H90N6O24·H3N. Mole weight: 1236.36. | |
| GM3NeuGc-Ganglioside | GM3NeuGc-Ganglioside is an indispensable compound, catering to studying cancer. It operates as a remarkable ganglioside variant responsible for pivotal cellular communication and immune system activation. Synonyms: a-Neu5Gc-(2-3)-b-Gal-(1-4)-b-Glc-(1-1)-Cer. | |
| GM4-Ganglioside | GM4-Ganglioside is an essential glycosphingolipid exhibiting tremendous potential as a research for neurodegenerative ailments including Alzheimer's disease and Parkinson's disease. Through its remarkable neuroprotective properties, GM4-Ganglioside safeguard neurons from degeneration. CAS No. 66456-69-7. Molecular formula: C57H106N2O17 xNa. Mole weight: 1091.45 (free acid basis). | |
| Gm anionic pept2 | Gm anionic pept2 is isolated from wax moth, Galleria mellonella and it has anti Gram-positive and antifungal activity. Synonyms: Gm anionic peptide 2. | |
| Gm apolipophoricin | Gm apolipophoricin is isolated from wax moth, Galleria mellonella and has anti-Gram-positive bacteria activity. | |
| GMBS | GMBS is a heterobifunctional cross-linker. GMBS can be used in chemical cross-linking of proteins coupled with mass spectrometry (CXMS) to study protein folding and to map the interfaces between interacting proteins [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 80307-12-6. Pack Sizes: 10 mg; 50 mg; 100 mg. Product ID: HY-W041994. |  |
| GMBS | A useful protective group in antibody drug conjugates. Synonyms: 4-Maleimidobutyric acid N-succinimidyl ester; N-(gamma-Maleimidobutyryloxy)succinimide; 4-Maleimidobutyric acid N-hydroxysuccinimide ester; 4-Maleimidobutyric acid n-succinimidyl ester; (GMBS);4-Maleimidobutyric acid NHS. Grades: ≥ 98%. CAS No. 80307-12-6. Molecular formula: C12H12N2O6. Mole weight: 280.23. | |
| GMBS | GMBS. Pack Sizes: Milligram Quantities: 100 mg. Order Number: I109. |  www.prochemonline.com |
| GMC 1-116 | GMC 1-116 is a metabolite of clozapine with weak 5-HT2 affinity and high M1 affinity (IC50 = 27 nM). Synonyms: 11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepin-8-ol; 8-Hydroxyclozapine; AC1L9SL1; 6-(4-methylpiperazin-1-yl)-5H-benzo[b][1,4]benzodiazepin-3-ol. Grades: 99%. CAS No. 63687-94-5. Molecular formula: C18H20N4O. Mole weight: 308.38. | |
| GMC 1-165 | GMC 1-165 is an analogue of clozapine with 5-HT2A/2C and hM1 receptor affinities. Synonyms: 11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepin-2-ol; 6-(4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepin-8-ol. Grades: 99%. CAS No. 156632-07-4. Molecular formula: C18H20N4O. Mole weight: 308.38. | |
| GMC 1-169 | GMC 1-169 is an atypical antipsychotic devoid of muscarinic activity. Uses: Atypical antipsychotic. Synonyms: [6-(4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepin-8-yl] trifluoromethanesulfonate. Grades: 99%. CAS No. 183140-97-8. Molecular formula: C19H19F3N4O3S. Mole weight: 440.44. | |
| GMC 15-27 | GMC 15-27 is a selective 5-HT1B/1D antagonist. Synonyms: 4'-(Aminoiminomethyl)-N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-[1,1'-biphenyl]-4-carboxamide. Grades: 98%. CAS No. 256227-71-1. Molecular formula: C27H31N5O2. Mole weight: 457.57. | |
| GMC 2-113 | GMC 2-113 is a selective 5-HT1B antagonist. Synonyms: BDBM50084961; ZINC13805066; N-[4-hydroxy-3-(4-methylpiperazin-1-yl)phenyl]-4-[2-methyl-4-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]benzamide. Grades: 98%. CAS No. 256227-77-7. Molecular formula: C28H29N5O3. Mole weight: 483.56. | |
| GMC 2-118 | GMC 2-118 is a potent and selective 5-HT1B antagonist. Synonyms: [4-[[4-[2-methyl-4-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]benzoyl]amino]-2-(4-methylpiperazin-1-yl)phenyl] methanesulfonate. Grades: 98%. CAS No. 256227-78-8. Molecular formula: C29H31N5O5S. Mole weight: 561.65. | |
| GMC 2-29 | GMC 2-29 is a potent and selective 5-HT1B/1D antagonist. Synonyms: N-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]-4-[2-methyl-4-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]benzamide. Grades: 99%. CAS No. 148672-15-5. Molecular formula: C29H31N5O3. Mole weight: 497.59. | |
| GMC 2-83 | GMC 2-83 is an atypical antipsychotic without muscarinic activity. Uses: Atypical antipsychotic. Synonyms: [6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepin-8-yl] trifluoromethanesulfonate. Grades: 99%. CAS No. 183140-98-9. Molecular formula: C19H18F3N3O4S. Mole weight: 441.42. | |
| GMC 3-15 | GMC 3-15 is a potent and selective 5-HT1B/1D antagonist. Synonyms: 4-[4-[[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]carbamoyl]phenyl]-3-methylbenzamide. Grades: 99%. CAS No. 691846-63-6. Molecular formula: C27H30N4O3. Mole weight: 458.55. | |
| GMC 61-39 | GMC 61-39 is a clozapine-like atypical antipsychotic. Uses: Atypical antipsychotic. Synonyms: [3-chloro-6-(4-methylpiperazin-1-yl)-5H-benzo[b][1,4]benzodiazepin-8-yl] trifluoromethanesulfonate. Grades: 98%. CAS No. 234113-94-1. Molecular formula: C19H18ClF3N4O3S. Mole weight: 474.88. | |
| g-Melanotropin | It has been located in the cryptic region of the ACTH/β-lipotropin precursor protein from the intermediate lobe of bovine pituitary. Synonyms: gamma-Melanocyte-stimulating hormone; Δ-MSH; γ2-MSH; gamma-melanotrophin. CAS No. 72711-43-4. Molecular formula: C74H99N21O16S. Mole weight: 1570.77. | |
| G. mellonella moricin-like peptide A | The moricin-like peptides were particularly active against filamentous fungi, preventing the growth of Fusarium graminearum at 3 microg/ml, and were also active against yeasts, gram-positive bacteria and gram-negative bacteria. | |
| GmoDef | GmoDef is isolated from Glossina morsitans [tsetse fly] and has antimicrobial activity. | |
| GMP | Guanosine 5'-monophosphate has been found to be useful in studies of modulation of glutamatergic neurotransmission. Synonyms: Guanosine-5'-monophosphate; 5'-Guanylic Acid. Grades: ≥ 95 % by HPLC. Molecular formula: C10H14N5O8P. Mole weight: 363.22. | |
| GMPαS | GMPαS, a synthesized protein of biotechnological application, is utilized in the biomedical sector for the purpose of investigation into the sprawling domain of inflammatory bowel disease (IBD). This recombinant compound fosters an effective anti-inflammatory response via the suppression of cytokine production associated with the onset of IBD. Additionally, GMPαS's therapeutic possibilities are gaining increasing scientific traction as a potential target for treating a gamut of autoimmune and underlying inflammatory maladies. Synonyms: Guanosine-5'-(α-thio)-monophosphate, Sodium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C10H14N5O7PS (free acid). Mole weight: 379.28 (free acid). | |
| GMP reductase | It converts nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and maintains intracellular balance of A and G nucleotides. In melanocytic cells, GMP reductase gene expression may be regulated by MITF. Group: Enzymes. Synonyms: guanosine 5'-monophosphate reductase; NADPH:GMP oxidoreductase (deaminating); guanosine monophosphate reductase; guanylate reductase; NADPH2:guanosine-5'-phosphate oxidoreductase (deaminating); guanosine 5'-phosphate reductase. Enzyme Commission Number: EC 1.7.1.7. CAS No. 9029-32-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1614; GMP reductase; EC 1.7.1.7; 9029-32-7; guanosine 5'-monophosphate reductase; NADPH:GMP oxidoreductase (deaminating); guanosine monophosphate reductase; guanylate reductase; NADPH2:guanosine-5'-phosphate oxidoreductase (deaminating); guanosine 5'-phosphate reductase. Cat No: EXWM-1614. | |
| GMP synthase (glutamine-hydrolysing) | Involved in the de novo biosynthesis of guanosine nucleotides. An N-terminal glutaminase domain binds L-glutamine and generates ammonia, which is transferred by a substrate-protective tunnel to the ATP-pyrophosphatase domain. The enzyme can catalyse the second reaction alone in the presence of ammonia. Group: Enzymes. Synonyms: GMP synthetase (glutamine-hydrolysing); guanylate synthetase (glutamine-hydrolyzing); guanosine monophosphate synthetase (glutamine-hydrolyzing); xanthosine 5'-phosphate amidotransferase; guanosine 5'-monophosphate synthetase. Enzyme Commission Number: EC 6.3.5.2. CAS No. 37318-71-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5805; GMP synthase (glutamine-hydrolysing); EC 6.3.5.2; 37318-71-1; GMP synthetase (glutamine-hydrolysing); guanylate synthetase (glutamine-hydrolyzing); guanosine monophosphate synthetase (glutamine-hydrolyzing); xanthosine 5'-phosphate amidotransferase; guanosine 5'-monophosphate synthetase. Cat No: EXWM-5805. | |
| GMQ | GMQ is a ASIC (acid-sensing ion) channel activator with an EC 50 value of 1.83 mM for ASIC3 at pH 7.4. GMQ opens only ASIC3 but no other ASICs at pH 7.4. GMQ can be used for neurological disease research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 5361-15-9. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-107757. | |
| GMQ hydrochloride | GMQ hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 5361-15-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GMQ hydrochloride | GMQ hydrochloride is a selective opener of acid-sensing ion channel 3 (ASIC3) at pH 7.4. It alters the pH dependence of ASIC1a and ASIC1b with no effect on the activation curve of ASIC2a. Synonyms: GMQ monohydrochloride; GMQ HCl; NSC-403387 hydrochloride; NSC 403387 hydrochloride; NSC403387 hydrochloride; NSC-403387 HCl; NSC 403387 HCl; NSC403387 HCl; N-(4-Methyl-2-quinazolinyl)-guanidine hydrochloride; 1-(4-Methylquinazolin-2-yl)guanidine hydrochloride. Grades: ≥98% by HPLC. CAS No. 5361-15-9. Molecular formula: C10H11N5.HCl. Mole weight: 237.69. | |
| GN 44028 | GN 44028 is a potent HIF-1α inhibitor (IC50 = 14 nM). It suppresses hypoxia-induced HIF-1α transcriptional activity with no effect on HIF-1α mRNA expression, HIF-1α protein accumulation, or HIF-1α/HIF-1β heterodimerization. Synonyms: GN44028; GN 44028; GN-44028; N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine. Grades: ≥98% by HPLC. CAS No. 1421448-26-1. Molecular formula: C18N15N3O2. Mole weight: 305.33. | |
| GNA2 N-Glycan | GNA2 N-Glycan is a resplendent biomedicine used for stduying cancer, inflammatory disorders, and neurodegenerative conditions. Synonyms: Monogalacto, fucosylated, biantennary N-linked glycan. | |
| Gnaphaline | A derivative of Flavoxate. Flavoxate is an anticholinergic with antimuscarinic effects. Synonyms: 4H-1-Benzopyran-4-one,5,7-dihydroxy-3,8-dimethoxy-2-phenyl-; 5,7-Dihydroxy-3,8-Dimethoxyflavon. Grades: > 95%. CAS No. 33803-42-8. Molecular formula: C17H14O6. Mole weight: 314.30. | |
| GNCP-2 | GNCP-2 is an antimicrobial cationic peptide found in Guinea pig neutrophils. It has antimicrobial activity. | |
| GNE-0877 | GNE0877 is a highly potent, selective, and brain-penetrant aminopyrazole leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitor with an IC50 of 3 nM. Synonyms: GNE0877; GNE 0877; GNE-0877. CAS No. 1374828-69-9. Molecular formula: C14H16F3N7. Mole weight: 339.326. | |
| GNE-140 racemate | GNE-140 racemate is a racemate mixture of (R)-GNE-140 and (S)-GNE-140. GNE-140 racemate is a potent lactate dehydrogenase A (LDHA) inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1802977-61-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100742. | |
| GNE-272 | GNE-272 is a potent and selective CBP/EP300 inhibitor with IC50s of 0.02, 0.03, 0.41 and 13 μM for CBP, EP300, BRET and BRD4, respectively. It shows significant antiproliferative effects in hematologic cancer cell lines and modulates MYC expression in vivo, corresponding to antitumor activity in AML tumor models. It is also a selective in vivo probe for the Bromodomains of CBP/EP300. Synonyms: (S)-1-(3-((2-fluoro-4-(1-methyl-1h-pyrazol-4-yl)phenyl)amino)-1-(tetrahydrofuran-3-yl)-1,4,6,7-tetrahydro-5h-pyrazolo[4,3-c]pyridin-5-yl)ethan-1-one; N-[2-Fluoro-4-(1-methyl-1H-pyrazole-4-yl)phenyl]-1-[(S)-tetrahydrofuran-3beta-yl]-5-acetyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-amine; 1-(3-{[2-fluoro-4-(1-methyl-1H-pyrazol-4-yl)phenyl]amino}-1-[(3S)-oxolan-3-yl]-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl)ethan-1-one. Grades: ≥95%. CAS No. 1936428-93-1. Molecular formula: C22H25FN6O2. Mole weight: 424.47. | |
| GNE 2861 | GNE-2861 is a potent and selective inhibitor of the group 2 p21-activated kinases (PAKs; IC50s = 7.5, 126, and 36 nM for PAK4, -5, and -6, respectively). Synonyms: 1-[2-[1-(2-Amino-4-pyrimidinyl)-2-[(2-methoxyethyl)amino]-1H-benzimidazol-6-yl]ethynyl]cyclohexanol; 1-[2-[3-(2-aminopyrimidin-4-yl)-2-(2-methoxyethylamino)benzimidazol-5-yl]ethynyl]cyclohexan-1-ol. Grades: ≥98% by HPLC. CAS No. 1394121-05-1. Molecular formula: C22H26N6O2. Mole weight: 406.48. | |
| GNE-317 | GNE-317 is a potent and selective PI3K inhibitor with potential anticncer activity. GNE-317 targets the PI3K pathway and can cross the Blood-Brain Barrier. GNE-317 was identified as having physicochemical properties predictive of low efflux by P-gp and BCRP. Studies in transfected MDCK cells showed that GNE-317 was not a substrate of either transporter. GNE-317 markedly inhibited the PI3K pathway in mouse brain, causing 40% to 90% suppression of the pAkt and pS6 signals up to 6-hour postdose. GNE-317 was efficacious in the U87, GS2, and GBM10 orthotopic models, achieving tumor growth inhibition of 90% and 50%, and survival benefit, respectively. GNE-317 could be effective in the treatment of GBM. Synonyms: GNE-317; GNE 317; GNE317. Grades: >98%. CAS No. 1394076-92-6. Molecular formula: C19H22N6O3S. Mole weight: 414.48. | |
| GNE-3500 | GNE-3500 has been found to be a Retinoic acid receptor-related Orphan receptor C agonist that could be probably significant in studies of some inflammatory diseases. Synonyms: GNE-3500; GNE 3500; GNE3500; 1-(4-(3-fluoro-4-(((3S,6R)-3-methyl-1,1-dioxido-6-phenyl-1,2-thiazinan-2-yl)methyl)phenyl)piperazin-1-yl)ethan-1-one. Grades: 98%. CAS No. 1537859-24-7. Molecular formula: C24H30FN3O3S. Mole weight: 459.58. | |
| GNE-3511 | GNE-3511 has been found to be a DLK, MAP3K12 kinase inhibitor that could probably exhibit protection action of primary neurons. IC50: 0.107 uM (DLK). Synonyms: GNE-3511; GNE 3511; GNE3511. CHEMBL3393333; SCHEMBL15602439; BDBM50059190; 2-[[6-(3,3-difluoropyrrolidin-1-yl)-4-[1-(oxetan-3-yl)piperidin-4-yl]pyridin-2-yl]amino]pyridine-4-carbonitrile. Grades: 98%. CAS No. 1496581-76-0. Molecular formula: C23H26F2N6O. Mole weight: 440.50. | |
| GNE-477 | GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor with IC50 of 4 nM for PI3Kα and Kiapp of 21 nM for mTOR. Synonyms: GNE-477, GNE477, GNE 477. Grades: >98%. CAS No. 1032754-81-6. Molecular formula: C21H28N8O3S2. Mole weight: 504.63. | |
| GNE-477 | GNE-477 is a dual inhibitor of PI3K (IC50 = 4 nM for PI3Kα) and mTOR (apparent Ki=21 nM). Group: Inhibitors. Alternative Names: GNE-477; GNE477; GNE 477. CAS No. 1032754-81-6. Molecular formula: C21H28N8O3S2. Mole weight: 504.63. Appearance: Solid powder. Purity: >98%. IUPACName: 5-(7-methyl-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinothieno[3,2-d]pyrimidin-2-yl)pyrimidin-2-amine. Canonical SMILES: NC1=NC=C (C2=NC (N3CCOCC3)=C4C (C (C)=C (CN5CCN (S (=O) (C)=O)CC5)S4)=N2)C=N1. Catalog: ACM1032754816. |  |
| GNE-493 | GNE-493 is a potent, selective, and orally available dual pan-PI3K/mTOR inhibitor with IC50s of 3.4/12/16/16/32 nM for PI3Kα /PI3Kβ /PI3Kγ /PI3Kδ /mTOR respectively. Synonyms: GNE493; GNE-493; GNE 493. Grades: >98%. CAS No. 1033735-94-2. Molecular formula: C17H20N6O2S. Mole weight: 372.44. | |
| GNE-495 | GNE-495 is a Selective MAP4K4 (Mitogen-activated protein kinase kinase kinase kinase 4) Inhibitor. IC50 value is 3.7 nM. GNE-495 shows excellent potency and good PK In vivo. GNE-495 was used to demonstrate in vivo efficacy in a retinal angiogenesis model recapitulating effects that are observed in the inducible Map4k4 knockout mice. Synonyms: GNE-495; GNE 495; GNE495. 8-amino-N-(1-(cyclopropanecarbonyl)azetidin-3-yl)-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide. Grades: 98%. CAS No. 1449277-10-4. Molecular formula: C22H20FN5O2. Mole weight: 405.43. | |
| GNE-4997 | GNE-4997, a pyrazol derivative, has been found to be an ITK inhibitor that could have significant biological activities. Ki: 0.09 nM. Synonyms: GNE-4997; GNE-4997; GNE-4997; (4aS,5aR)-N-(1-((R)-((R)-1,1-dioxidotetrahydro-2H-thiopyran-2-yl)(phenyl)methyl)-1H-pyrazol-4-yl)-5,5-difluoro-5a-methyl-1,4,4a,5,5a,6-hexahydrocyclopropa[f]indazole-3-carboxamide. Grades: 98%. CAS No. 1705602-02-3. Molecular formula: C25H27F2N5O3S. Mole weight: 515.58. | |
| GNE-617 | GNE-617 is a novel and specific Nampt inhibitor with an IC50 of 18.9 nM in A549 cell. Synonyms: GNE-617; GNE 617; GNE617. Grades: >98%. CAS No. 1362154-70-8. Molecular formula: C21H15F2N3O3S. Mole weight: 427.42. | |
| GNE-617 | GNE-617 Inhibitor. Uses: Scientific use. Product Category: T4335. CAS No. 1362154-70-8. |  |
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