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Ionomycin is a selective calcium ionophore antibiotic isolated from Streptomyces species. Anti-Gram-positive activity. Synonyms: 10,16-Docosadienoic acid, 11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-, (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-; (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-Trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-10,16-docosadienoic acid; 10,16-Docosadienoic acid, 11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[octahydro-5'-(1-hydroxyethyl)-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-, [2S-[2α[2'S*,5'R*(S*)],5β(4S*,6R*,8R*,10Z,12S*,14S*,16E,18S*,19S*,20R*,21R*)]]-; [2S-[2α[2'S*,5'R*(S*)],5β(4S*,6R*,8R*,10Z,12S*,14S*,16E,18S*,19S*,20R*,21R*)]]-11,19,21-Trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[octahydro-5'-(1-hydroxyethyl)-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-10,16-docosadienoic acid; SQ 23377; EM 94. Grade: >98% by HPLC. CAS No. 56092-81-0. Molecular formula: C41H72O9. Mole weight: 709.00.
Ionomycin calcium
Ionomycin calcium (SQ23377 calcium) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin calcium (SQ23377 calcium) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin calcium (SQ23377 calcium) also induces the activation of protein kinase C (PKC) [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: SQ23377 calcium. CAS No. 56092-82-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-13434A.
Ionomycin Calcium Salt
Antibiotic that acts as a potent and selective calcium ionophore; more effective than A23187. Ionomycin binds Ca2+ in the 7.0-9.5 pH range with the resulting complex exhibiting intense UV absorption. Ionomycin Calcium is a polyether antibiotic obtained from Streptomyces conglobatus by solvent extraction. It is different from other antibiotics of its class as it absorbs UV light at 300nm maximum. Gram-positive antibiotic. Group: Biochemicals. Alternative Names: Calcium Ionomycin; (4R, 6S, 8S, 10Z, 12R, 14R, 16E, 18R, 19R, 20S, 21S)-11, 19, 21-Trihydroxy-4, 6, 8, 12, 14, 18, 20-heptamethyl-22-[(2S, 2R, 5S, 5S)-octahydro-5-[(1R)-1-hydroxyethyl]-2, 5-dimethyl[2, 2-bifuran]-5-yl]-9-oxo-10, 16-Docosadienoic Acid Calcium Salt. Grades: Highly Purified. CAS No. 56092-82-1. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C41H70O9 Ca, Molecular Weight: 747.07. US Biological Life Sciences.
Worldwide
Ionomycin Calcium Salt
The Calcium Salt of Ionomycin, a kind of polyether antibiotic, is a selective calcium ionophore obtained from Streptomyces conglobatus by solvent extraction. It is more effective than A23187 as a calcium ionophore. It is used to study the transport of calcium ions on biological membranes. It can induce apoptotic degeneration of embryonic cortical neurons. Synonyms: Calcium ionophore; Calcium Ionomycin; (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-Trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-10,16-Docosadienoic Acid Calcium Salt; 10,16-Docosadienoic acid, 11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-, calcium salt (1:1), (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-; Ionomycin, calcium salt (1:1). Grade: ≥98%. CAS No. 56092-82-1. Molecular formula: C41H70O9Ca. Mole weight: 747.07.
Ionomycin calcium salt from Streptomyces conglobatus
Ionomycin free acid. Group: Biochemicals. Grades: Purified. CAS No. 56092-81-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Ionomycin free acid
1mg Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C41H72O9. CAS No. 56092-81-0. Prepack ID 22000466-1mg. Molecular Weight 709. See USA prepack pricing.
Ionomycin (Free Acid)
Antibiotic. Potent and highly selective Ca2+ ionophore. Commonly used to modify intracellular calcium levels to study calcium transport across biological membranes and to calibrate fluorescent Ca2+ indicators. Ionomycin also transports Pb2+ and some other divalent cations, as well as several lanthanide series trivalent cations at efficiencies that are greater than or equal to those for Ca2+. Apoptosis inducer. Induces apoptotic neuronal degeneration in embryonic cortical neurons and cell cycle arrest at G1 phase and induces central demyelination. Used to stimulate the intracellular production of the cytokines, interferon, perforin, IL-2 and IL-4 usually in conjunction with PMA. ADAM10 agonist. Potent inducer of shedding CXCL16. TREK-1 channels inhibitor. PPARy ligand with a unique binding mode. Shows effective glucose-lowering activity in a mouse model of diabetes. Group: Biochemicals. Alternative Names: SQ 23377; EM 94; [2S-[2α[2S*, 5R*(S*)], 5 β(4S*, 6R*, 8R*, 10Z, 12S*, 14S*, 16E, 18S*, 19S*, 20R*, 21R*)]]-11, 19, 21-Trihydroxy-4, 6, 8, 12, 14, 18, 20-heptamethyl-22-[octahydro-5-(1-hydroxyethyl)-2, 5-dimethyl[2, 2-bifuran]-5-yl]-9-oxo-10, 16-docosadienoic Acid; [2S-[2α[2S*, 5R*(S*)], 5 β(4S*, 6R*, 8R*,. Grades: Highly Purified. CAS No. 56092-81-0. Pack Sizes: 1mg, 5mg. Molecular Formula: C??H??O?. US Biological Life Sciences.
Ionone Beta Natural 50% In Ethyl Alcohol. CAS No. MIXTURE. Kosher: Y. VIGON Item # 507626. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers.
America & Internationally
Iopamidol
Nonionic radiocontrast medium. Diagnostic aid (radiopaque medium). Group: Biochemicals. Alternative Names: N,N-Bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[[(2S)-2-hydroxy-1-oxopropyl]amino]-2,4,6-triiodo-1,3-benzenedicarboxamide; Iomapidol; B-15000; SQ-13396; Iopamiro; Iopamiron; Isovue; Jopamiro; Niopam; Solutrast. Grades: Highly Purified. CAS No. 60166-93-0. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Iopamidol
Iopamidol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Iopamidol. Appearance: White Crystalline Powder. CAS No. 60166-93-0. Molecular formula: C17H22I3N3O8. Mole weight: 777.09. Purity: 95%+. IUPACName: (S)-N,N-Bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-5-lactam. Density: 2.281 g/cm³. Product ID: ACM60166930. Alfa Chemistry ISO 9001:2015 Certified.
Iopamidol
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardspesticides & metabolitespharma & vet compounds & metabolitespharma & vet compounds & metabolitesapi standardseuropean pharmacopoeia (ph. eur.)pharmaceutical toxicologypharmacopoeial standards. Alternative Names: Iopamidol, N,N'-Bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[[(2S)-2-hydroxypropanoyl]amino]-2,4,6-triiodobenzene-1,3-dicarboxamide.
Iopamidol
1g Pack Size. Group: Analytical Reagents, Biochemicals, Organics, Research Organics & Inorganics. Formula: C17H22I3N3O8. CAS No. 62883-00-5. Prepack ID 20932439-1g. Molecular Weight 777.09. See USA prepack pricing.
Iopamidol
Iopamidol is a nonionic, X-Ray iodinated contrast agent (CA) for a wide variety of diagnostic applications. Iopamidol contains amide and hydroxyl functionalities that can be exploited for the generation of the chemical exchange saturation transfer (CEST) contrast [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: B-15000; SQ-13396. CAS No. 60166-93-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0684.
Iopamidol-d3
Labeled nonionic radiocontrast medium. Diagnostic aid (radiopaque medium). Group: Biochemicals. Alternative Names: N,N-Bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[[(2S)-2-hydroxy-1-oxopropyl-d3]amino]-2,4,6-triiodo-1,3-benzenedicarboxamide; Iomapidol-d3; B-15000-d3; SQ-13396-d3; Iopamiro-d3; Iopamiron-d3; Isovue-d3; Jopamiro-d3; Niopam-d3; Solutrast-d3. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Iopamidol-[d3]
A labelled nonionic radiocontrast medium. Diagnostic aid (radiopaque medium). Synonyms: N,N'-Bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[[(2S)-2-hydroxy-1-oxopropyl-d3]amino]-2,4,6-triiodo-1,3-benzenedicarboxamide; Iomapidol-d3; Iopamiro-d3; Iopamiron-d3; Isovue-d3; Jopamiro-d3; Niopam-d3; Solutrast-d3. Grade: 97%. CAS No. 1217831-76-9. Molecular formula: C17H19D3I3N3O8. Mole weight: 780.10.
Iopamidol-d8
Labeled Iopamidol, a nonionic radiocontrast medium. Diagnostic aid (radiopaque medium). Group: Biochemicals. Alternative Names: N,N-Bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[[(2S)-2-hydroxy-1-oxopropyl]amino]-2,4,6-triiodo-1,3-benzenedicarboxamide-d8; Iomapidol-d8; B-15000-d8; SQ-13396-d8; Iopamiro-d8; Iopamiron-d8; Isovue-d8; Jopamiro-d8; Niopam-d8; Solutrast-d8. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Iopamidol EP Impurity F
Iopamidol EP Impurity F. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1869069-71-5. Molecular formula: C16H20I3N3O6. Mole weight: 731.06. Catalog: APB1869069715.
Iopamidol Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Iopamidol Related Compound B
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Iopamidol Related Compound C
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Iopanoic acid
Iopanoic acid is an inhibitor of 5'-Deiodinase and also an iodinated contrast medium. Uses: Scientific research. Group: Signaling pathways. CAS No. 96-83-3. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1664.
Iopromide EP Impurity H. Uses: For analytical and research use. Group: Impurity standards. CAS No. 185459-57-8. Molecular formula: C14H15I3N2O7. Mole weight: 703.99. Catalog: APB185459578.
Iopromide Impurity 11
Iopromide Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 102275-80-9. Molecular formula: C26H30I3N3O12. Mole weight: 957.24. Catalog: APB102275809.
Iopromide Impurity 17
Iopromide Impurity 17. Uses: For analytical and research use. Group: Impurity standards. CAS No. 103254-63-3. Molecular formula: C19H26I3N3O8. Mole weight: 805.14. Catalog: APB103254633.
Iopromide Impurity 21
Iopromide Impurity 21. Uses: For analytical and research use. Group: Impurity standards. CAS No. 102356-49-0. Molecular formula: C4H10ClNO. Mole weight: 123.58. Catalog: APB102356490.
Iopromide Impurity 28
Iopromide Impurity 28. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1009809-15-7. Molecular formula: C18H26IN3O8. Mole weight: 539.32. Catalog: APB1009809157.
Iopromide Impurity 45
Iopromide Impurity 45. Uses: For analytical and research use. Group: Impurity standards. CAS No. 132327-79-8. Molecular formula: C3H8ClNO. Mole weight: 109.55. Catalog: APB132327798.
Iopromide Impurity 6
Iopromide Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 103254-70-2. Molecular formula: C17H22I3N3O8. Mole weight: 777.09. Catalog: APB103254702.
Iopromide Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Iopromide Related Compound B
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
iota-Carrageenan
iota-Carrageenan. Group: Molecular Biology. CAS No. 9062-7-1. Pack Sizes: 25g, 500g. US Biological Life Sciences.
Worldwide
Iotalamic acid
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Iotalamic acid
Lotalamic acid (Iothalamic acid) is a contrast agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Iothalamic acid. CAS No. 2276-90-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B1053.
Iothalamic Acid
Iothalamic Acid. Group: Biochemicals. Alternative Names: 3- (Acetylamino) -2, 4, 6-triiodo-5-[ (methylamino) carbonyl]benzoic Acid; 5-Acetamido-2,4,6-triiodo-N-methylisophthalamic Acid; 5-Acetylamino-2,4,6-triiodo-N-methyl-3-isophthalamic Acid; Cysto Conray II; Iotalamic Acid; MI 216; Methalamic Acid. Grades: Highly Purified. CAS No. 2276-90-6. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Ioversol
Nonionic, low osmolality, radiographic contrast agent. Diagnostic aid (radiopaque medium). Group: Biochemicals. Alternative Names: N,N'-bis(2,3-dihydroxypropyl)-5-[(hydroxyacetyl)(2-hydroxyethyl)amino]-2. Grades: Highly Purified. CAS No. 87771-40-2. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Ioversol
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Ioversol
Ioversol (MP-328) is a nonionic iodinated contrast medium (CM) that is used during a CT scan or x-ray in animal experiment. Ioversol does not damage the blood-brain barrier (BBB) in animal [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MP-328. CAS No. 87771-40-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B1410.
Ioversol Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Ioversol Related Compound B
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Histone demethylase JMJD inhibitor (IC50 values are 0.12, 0.17, 0.2, 0.3, 0.6 and 1um for JMJD3, JMJD1A, JMJD2A, JMJD2E, JMJD2C and UTX respectively). Cell permeable; inhibits JMJD2A-mediated H3K9me3 demethylation in HeLa cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 5852-78-8. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
IOX2
IOX2 is a specific prolyl hydroxylase-2 ( PHD2 ) inhibitor with IC 50 of 22 nM. IOX2 regulates platelet function and arterial thrombosis by upregulating HIF-1α expression and inhibiting ROS production. IOX2 can be used in the study of thrombotic diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 931398-72-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15468.
IOX4 is a selective HIF prolyl-hydroxylase 2 (PHD2) inhibitor with an IC50 value of 1.6 nM, induces HIF? in cells and in wildtype mice with marked induction in the brain tissue. IOX4 competes with and displaces 2-oxoglutarate (2OG) at the active site of PHD2[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1154097-71-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-120110.
Ioxaglic acid
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardseuropean pharmacopoeia (ph. eur.)pharmacopoeial standards. Alternative Names: 3-[[[[3-(Acetylmethylamino)-2,4,6-triiodo-5-(methylcarbamoyl)benzoyl]amino]acetyl]amino]-5-[(2-hydroxyethyl)carbamoyl]-2,4,6-triiodobenzoic acid,Ioxaglic acid.
Ioxilan
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Ioxilan
Ioxilan is a low-osmolar, nonionic and tri-iodinated diagnostic contrast agent. Ioxilan is also an X-ray contrast agent for excretory urography and contrast enhanced computed tomographic (CECT) imaging of the head and body. Intravascular injection results in opacification of vessels in the path of flow of the contrast medium, permitting radiographic visualization of the internal structures of the human body until significant hemodilution occurs [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 107793-72-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-109513.
Ioxilan
Ioxilan. Group: Biochemicals. Alternative Names: 5-[Acetyl(2,3-dihydroxypropyl)amino]-N1-(2,3-dihydroxypropyl)-N3-(2-hydroxyethyl)-2,4,6-triiodo-1,3-benzenedicarboxamide. Grades: Highly Purified. CAS No. 107793-72-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C18H24I3N3O8. US Biological Life Sciences.
Worldwide
Ioxilan(400 mg)
Ioxilan(400 mg). Uses: Designed for use in research and industrial production. Additional or Alternative Names: IOXILAN (400 MG);1,3-Benzenedicarboxamide, 5-[acetyl(2,3-dihydroxypropyl)amino]-N-(2,3-dihydroxypropyl)-N'-(2-hydroxyethyl)-2,4,6-triiodo-;Ioxitol;Oxilan 300. Product Category: Heterocyclic Organic Compound. CAS No. 107793-72-6. Molecular formula: C18H24I3N3O8. Mole weight: 791.101. Product ID: ACM107793726. Alfa Chemistry ISO 9001:2015 Certified.
Ioxitalamic Acid
A substituted 2,4,6-triiodobenzoic acid, an excellent contrast media for ventriculography, radiculography, lumbar myelography and x-rays of the cardiovascular system. Group: Biochemicals. Alternative Names: 3- (Acetylamino) -5-[[ (2-hydroxyethyl) amino]carbonyl]-2, 4, 6-triiodobenzoic Acid;3-Acetamido-2,4,6-triiodo-(N- β -hydroxyethyl) isophthalic Acid Monoamide; AG 58107; Ioxitalamate. Grades: Highly Purified. CAS No. 28179-44-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Ioxitalamic Acid-d4
A substituted 2,4,6-triiodobenzoic acid, an excellent contrast media for ventriculography, radiculography, lumbar myelography and x-rays of the cardiovascular system. Group: Biochemicals. Alternative Names: 3-(Acetylamino)-5-[[(2-hydroxyethyl-d4)amino]carbonyl]-2,4,6-triiodobenzoic Acid;3-Acetamido-2,4,6-triiodo-(N- β-hydroxyethyl-d4)isophthalic Acid Monoamide; AG 58107-d4; Ioxitalamate-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
IOXYNIL-METHYL. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Ioxynil-methyl, 3,5-Diiodo-4-methoxybenzonitrile, AC1N3QGA, SureCN10762528, 36198_RIEDEL, 36198_FLUKA, FT-0603634, 3336-40-1. Product Category: Heterocyclic Organic Compound. CAS No. 3336-40-1. Molecular formula: C8H5I2NO. Mole weight: 384.94. Purity: 0.96. IUPACName: 3,5-diiodo-4-methoxybenzonitrile. Canonical SMILES: COC1=C(C=C(C=C1I)C#N)I. Density: 2.37g/cm³. Product ID: ACM3336401. Alfa Chemistry ISO 9001:2015 Certified.
IP-10 from rat
recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
IP6K2-IN-2
IP6K2-IN-2 (Compound 6) is an IP6K2 inhibitor, with IC 50 values of 0.58 μM ( IP6K2 ), 0.86 μM ( IP6K1 ) and 3.08 μM ( IP6K3 ). IP6K2-IN-2 can be used in research of obesity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2967648-66-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-122706A.
IP7e
IP7e is a potent, brain-penetrant and orally active Nurr1 activator with an EC50 value of 3.9 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 500164-74-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110274.