A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Linvoseltamab is a bispecific antibody targeting to both BCMA ( TNFRSF17 ) and CD3 epsilon. Linvoseltamab shows safety profile and encouraging efficacy in relapsed/refractory multiple myeloma (RRMM) models [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN5458. CAS No. 2408319-25-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9989.
Linzagoli impurity 3
Linzagoli impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1033103-05-7. Molecular formula: C7H8FNO2. Mole weight: 157.14. Catalog: APB1033103057.
Linzagolix
Linzagolix (KLH-2109; OBE-2109) is a potent, non-peptide, and orally active GnRH antagonist. Linzagolix can be used for uterine fibroids, endometriosis, adenomyosis research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KLH-2109; OBE-2109. CAS No. 935283-04-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109093.
Lions Mane (Hericium Herinaceus) P.E. 30% Polysaccharides UV
Lions Mane (Hericium Herinaceus) P.E. 30% Polysaccharides UV.
CA, FL & NJ
Liothyronine
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Liothyronine
Liothyronine is an active form of thyroid hormone. Liothyronine binds to thyroid hormone receptors TRα and TRβ with K i s of 2.33 and 2.29 nM for hTRα and hTRβ, respectively. Liothyronine also binds to PVR and blocks the interaction of TIGIT/PVR [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Triiodothyronine; 3,3',5-Triiodo-L-thyronine; T3. CAS No. 6893-2-3. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-A0070A.
Liothyronine-acyl-D-glucuronide is a crucial compound used for studying the metabolisms of liothyronine, a compound used in the research of hypothyroidism. Acting as a metabolite, this compound aids in the understanding of drug interactions, metabolism pathways and potential side effects associated with liothyronine therapy. Molecular formula: C21H20I3NO10. Mole weight: 827.10.
Liothyronine acyl glucuronide
The acyl glucuronidated metabolite of Liothyronine which is a synthetic form of triiodothyronine produced by the thyroid gland that is involved in the maintenance of metabolic homeostasis. Synonyms: Liothyronine Acyl Glucuronide; T3 Acyl Glucuronide; O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo- L-Tyrosine 1-ester with β-D-Glucopyranuronic Acid; Triiodothyronine Acyl Glucuronide; Glucuronic Acid 1-Ester with 3-[4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenyl]alanine. Grades: > 95%. CAS No. 910907-23-2. Molecular formula: C21H20I3NO10. Mole weight: 827.11.
Liothyronine Impurity B
An impurity of Liothyronine which is used to treat an underactive thyroid (hypothyroidism) and replaces or provides more thyroid hormone, which is normally made by the thyroid gland. Grades: > 95%. Molecular formula: C9H9I2NO3. Mole weight: 432.99.
Liothyronine Impurity C
An impurity of Liothyronine which is a man-made form of thyroid hormone used to treat an underactive thyroid (hypothyroidism). Grades: > 95%. Molecular formula: C14H9I3O4. Mole weight: 621.94.
Liothyronine Impurity D
An impurity of Liothyronine which is normally synthesized and secreted by the thyroid gland in much smaller quantities than L-tetraiodothyronine. Synonyms: Tetrac; 67-30-1; Tetraiodothyroacetic acid; 3,3',5,5'-TETRAIODOTHYROACETIC ACID; T4-acetic acid; 2-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)acetic acid; 3,5,3',5'-Tetraiodo Thyroacetic Acid; Benzeneacetic acid, 4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-; Thyroacetic acid, 3,3',5,5'-tetraiodo-; PA7UX1FFYQ; 3,5-Diiodo-4-(4-hydroxy-3,5-diiodophenoxy)benzeneacetic acid; 2-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]acetic acid; Acide 3,5,3',5'-tetraiodothyroacetique. Grades: > 95%. Molecular formula: C14H8I4O4. Mole weight: 747.84.
Liothyronine Impurity E
An impurity of Liothyronine which is a man-made form of thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Synonyms: diiodothyronine; O-(4-HYDROXYPHENYL)-3,5-DIIODO-L-TYROSINE; 3,5-DIIODO-L-THYRONINE; 3,5-DIIODO-4-(4-HYDROXYPHENOXY)-L-PHENYLALANINE; L-TYROSINE, O-(4-HYDROXYPHENYL)-3,5-DIIODO-; 3-5-diiodo-L-thyronine crystalline; 3,5-diiodothyronine. Grades: > 95%. CAS No. 1041-01-6. Molecular formula: C15H13I2NO4. Mole weight: 525.08.
Liothyronine related impurity, (R)-2-amino
An impurity of Liothyronine which is normally synthesized and secreted by the thyroid gland in much smaller quantities than L-tetraiodothyronine. Grades: > 95%. Molecular formula: C15H12I3NO4. Mole weight: 650.98.
Liothyronine sodium
Liothyronine sodium is an active form of thyroid hormone. Liothyronine sodium is a potent thyroid hormone receptors TRα and TRβ agonist with K i s of 2.33 nM for hTRα and hTRβ, respectively [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Triiodothyronine sodium; 3,3',5-Triiodo-L-thyronine sodium; T3 sodium. CAS No. 55-06-1. Pack Sizes: 100 mg; 500 mg. Product ID: HY-A0070.
Liothyronine Sodium
Liothyronine Sodium is the most potent form of thyroid hormone acting on the body to increase the basal metabolic rate, affect protein synthesis. Synonyms: Cytomel; Triostat; 3,3',5-Triiodo-L-Thyronine Sodium Salt. Grades: ≥ 98% (HPLC). CAS No. 55-06-1. Molecular formula: C15H12I3NO4.Na. Mole weight: 672.96.
Liothyronine sodium hydrate
Liothyronine sodium hydrate is an active form of thyroid hormone. Liothyronine sodium hydrate is a potent thyroid hormone receptors TRα and TRβ agonist with K i s of 2.33 nM for hTRα and hTRβ, respectively [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Triiodothyronine sodium hydrate; 3,3',5-Triiodo-L-thyronine sodium hydrate; T3 sodium hydrate. CAS No. 345957-19-9. Pack Sizes: 100 mg. Product ID: HY-A0070B.
Liothyronine sulfate
The sulfoconjugated metabolite of Liothyronine which is a thyroid hormone used to treat hypothyroidism. Synonyms: Triiodothyronine Sulfate; 3,5-Diiodo-O-[3-iodo-4-(sulfooxy)phenyl]-L-tyrosine; 3-[4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenyl]-L-alanine Hydrogen Sulfate; Triiodothyronine Hydrogen Sulfate; Liothyronine Sulfate; T3 Sulfate. Grades: > 95%. CAS No. 31135-55-4. Molecular formula: C15H12I3NO7S. Mole weight: 731.04.
Lipase
Lipase. Uses: Designed for use in research and industrial production. Additional or Alternative Names: LIPASE AS AMANO;LIPASE AK AMANO;LIPASE AYS AMANO;LIPASE CAL-A, THERMOSTABLE;LIPASE CAL-B;LIPASE M AMANO 10;LIPASE MML;LIPASE PS AMANO. Appearance: solution. CAS No. 9001-62-1. Molecular formula: n.a. Mole weight: 0. Purity: 0.95. Product ID: ACM9001621. Alfa Chemistry ISO 9001:2015 Certified.
Lipase
An enzyme capable of hydrolyzing fats and oils. Typically used in dietary supplements. Suitable for other food grade applications. Applications: Dietary supplements. Group: Enzymes. Synonyms: Lipase. CAS No. 9001-62-1. Lipase. Appearance: powder or liquid. Source: Rhizopus oryzae. Lipase Feed Grade Enzymes; digestion and utilization of fat; for Fish; piglet; fowl; Feed;Lipase; Feed Grade Enzymes; Lipase Feed Grade Enzymes; FEED-2321. Pack: 25kg/paper barrel (powder form), 30kg/polyster barrel (liquid form). Cat No: DIS-1026.
An active lipase-based enzyme blend used with conditioning agents in cosmetic-based masks, facial and skin cleansers, skin creams and makeup removers. It breaks down human sebum and residual oil from cosmetics leaving skin feeling silky smooth. Applications: Cosmetic. Group: Enzymes. Synonyms: Lipase; Cosmetic; lipase-based enzyme blend; breaks down human sebum; breaks down residual oil; human sebum; breaks down human sebum and residual oil; residual oil; human sebum; Lipase-based enzyme blend for cosmetic. Cosmetic enzymes. Appearance: powder or liquid. Lipase; Cosmetic; lipase-based enzyme blend; breaks down human sebum; breaks down residual oil; human sebum; breaks down human sebum and residual oil; residual oil; human sebum; Lipase-based enzyme blend for cosmetic. Pack: 25kg/paper barrel (powder form), 30kg/polyster barrel (liquid form). Cat No: BODY-2811.
Lipase-based enzyme blend for shampoos
As an active lipase-based enzyme blend used with conditioning agents in shampoos and hair conditioners to dissolve accumulated oils leaving hair clean, non-oily and silky soft. Applications: Shampoos. Group: Enzymes. Synonyms: Lipase; Lipase-based enzyme blend; shampoos; enzyme for shampoos; lipase-based enzyme; dissolve accumulated oils; leaving hair clean; dissolve oils; Lipase-based enzyme blend for shampoos. Cosmetic enzymes. Appearance: powder or liquid. Lipase; Cosmetic; lipase-based enzyme blend; breaks down human sebum; breaks down residual oil; human sebum; breaks down human sebum and residual oil; residual oil; human sebum; Lipase-based enzyme blend for cosmetic. Pack: 25kg/paper barrel (powder form), 30kg/polyster barrel (liquid form). Cat No: BODY-2815.
Lipase B Candida antarctica, recombinant from Aspergillus oryzae
Lipase B from Candida antarctica has been shown to be an effective catalyst for the synthesis of esters of ethyl D-glucopyranoside from fatty acids larger than octanoic acid. It has also been found to catalyze a wide variety of organic reactions including many different regio-and enantio-selective syntheses. Applications: Lipases are used industrially for the resolution of chiral compounds and the transesterification production of biodiesel. Group: Enzymes. Synonyms: EC 3.1.1.3; lipase; triglyceride lipase; tributyrase; butyrinase; glycerol ester hydrolase; t. Enzyme Commission Number: EC 3.1.1.3. CAS No. 9001-62-1. Lipase. Activity: ~9 units/mg. Storage: 2-8°C. Form: powder, beige. Source: Aspergillus oryzae. Species: Candida Antarctica. EC 3.1.1.3; lipase; triglyceride lipase; tributyrase; butyrinase; glycerol ester hydrolase; tributyrinase; Tween hydrolase; steapsin; triacetinase; tributyrin esterase; Tweenase; amno N-AP; Takedo 1969-4-9; Meito MY 30; Tweenesterase; GA 56; capalase L; triglyceride hydrolase; triolein hydrolase; tween-hydrolyzing esterase; amano CE; cacordase; triglyceridase; triacylglycerol ester hydrolase; amano P; amano AP; PPL; glycerol-ester hydrolase; GEH; meito Sangyo OF lipase; hepatic lipase; lipazin; post-heparin plasma protamine-resistant lipase; salt-resistant post-heparin lipase; heparin releasable hep
It can promote the digestion and absorption of fat in the daily diets, increase feed conversion ratio and meet the requirements for high energy rations. 1.Supplying the endogenous digestive enzyme (Perfecting the digestive enzyme system of animals), meeting the demand of animals for daily diets of high energy. 2. Improving nutrition of the feed, especially digestion and utilization of fat, increasing the feed conversion rate. 3. Reducing weanling stress of piglets, obviously reducing its diarrhea and alimentary canal diseases and improving survival rate. 4. Enhancing bait percentage in aquiculture, improving fat utilization and reducing formation of fatty liver. 5.Protecting animal health, increasing average daily gain and production capacity, improving meat quality. 6. Boosting absorption and utilization of fat-soluble vitamin and other micro element. Applications: Fish, piglet, fowl,others. Group: Enzymes. Synonyms: Lipase Feed Grade Enzymes; digestion and utilization of fat; for Fish; piglet; fowl; Feed;Lipase; Feed Grade Enzymes; Lipase Feed Grade Enzymes; FEED-2321. CAS No. 9001-62-1. Lipase. Appearance: powder. Lipase Feed Grade Enzymes; digestion and utilization of fat; for Fish; piglet; fowl; Feed;Lipase; Feed Grade Enzymes; Lipase Feed Grade Enzymes; FEED-2321. Pack: 25kg/barrel or subject to client requirement. Cat No: FEED-2321.
100g Pack Size. Group: Analytical Reagents, Biochemicals, Diagnostic Raw Materials. Formula: N/A. CAS No. 9001-62-1. Prepack ID 82941408-100g. See USA prepack pricing.
Lipase from Pseudomonas cepacia
Triacylglycerol lipase is an enzyme with system name triacylglycerol acylhydrolase. This enzyme catalyses the following chemical reaction:triacylglycerol + H2O<-> diacylglycerol + a carboxylate. Group: Enzymes. Synonyms: PS Lipase; Triacylglycerol acylhydrolase; Triacylglycerol lipase. Enzyme Commission Number: EC 3.1.1.3. CAS No. 9001-62-1. Lipase. Activity: >30 U/mg. Appearance: Light beige powder. Storage: at -20°C. Source: Pseudomonas cepacia. EC 3.1.1.3; lipase; triglyceride lipase; tributyrase; butyrinase; glycerol ester hydrolase; tributyrinase; Tween hydrolase; steapsin; triacetinase; tributyrin esterase; Tweenase; amno N-AP; Takedo 1969-4-9; Meito MY 30; Tweenesterase; GA 56; capalase L; triglyceride hydrolase; triolein hydrolase; tween-hydrolyzing esterase; amano CE; cacordase; triglyceridase; triacylglycerol ester hydrolase; amano P; amano AP; PPL; glycerol-ester hydrolase; GEH; meito Sangyo OF lipase; hepatic lipase; lipazin; post-heparin plasma protamine-resistant lipase; salt-resistant post-heparin lipase; heparin releasable hepatic lipase; amano CES; amano B; tributyrase; triglyceride lipase; liver lipase; hepatic monoacylglycerol acyltransferase; 9001-62-1. Cat No: NATE-1611.
Pancreatic lipase. Contains 19. 6 USP units per milligram. Keep refrigerated. Health Risk: 0. Flammability: 0. Reactivity: 1. Uses: Hydrolyzes triacylglycerols (fats) into fatty acids and glycerol. Alternative Names: Steapsin. Grades: chem-grade laboratory. CAS No. 9001-62-1. Product ID: 872500. -- SOLD FOR EDUCATIONAL USE ONLY --
Lipase-polyethylene glycol
A lipase is an enzyme that catalyzes the hydrolysis of fats (lipids). Lipases are a subclass of the esterases. Lipases perform essential roles in the digestion, transport and processing of dietary lipids (e.g. triglycerides, fats, oils) in most, if not all, living organisms. Genes encoding lipases are even present in certain viruses. Most lipases act at a specific position on the glycerol backbone of lipid substrate (A1, A2 or A3) (small intestine). Several other types of lipase activities exist in nature, such as phospholipases and sphingomyelinases, however these are usually treated separately from "conventional" lipases. Some lipases are expressed and secreted by pathogenic organisms during the infection. Group: Enzymes. Synonyms: PEG-Lipase; Lipase-polyethylene glycol. Lipase. Activity: ~75,000 units/mg protein (using olive oil). Storage: -20°C. Form: Lyophilized powder containing PEG. PEG-Lipase; Lipase-polyethylene glycol. Pack: Package size based on protein content. Cat No: NATE-0539.
for the titrimetric determination of enzyme activity. Group: Fluorescence/luminescence spectroscopy.
Lipase (Yeast)
A lipase enzyme that gives non-specific fat and oil hydrolysis over a broad pH range. Applications: Dietary supplements. Group: Enzymes. Synonyms: Lipase; (Yeast). CAS No. 9001-62-1. Lipase. Appearance: powder or liquid. Source: Candida cylindracea (Candida rugosa). Lipase Feed Grade Enzymes; digestion and utilization of fat; for Fish; piglet; fowl; Feed;Lipase; Feed Grade Enzymes; Lipase Feed Grade Enzymes; FEED-2321. Pack: 25kg/paper barrel (powder form), 30kg/polyster barrel (liquid form). Cat No: DIS-1027.
Lipid 5
Lipid 5 is an amino lipid that affords efficient mRNA delivery in rodent and primate models. Lipid 5 shows optimal pharmacokinetics and non-toxic side effects [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 2089251-33-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138171.
lipid-A-disaccharide synthase
Involved with EC 2.3.1.129 (acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase) and EC 2.7.1.130 (tetraacyldisaccharide 4'-kinase) in the biosynthesis of the phosphorylated glycolipid, lipid A, in the outer membrane of Escherichia coli. Group: Enzymes. Synonyms: UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine:2,3-bis-(3-hydroxytetradecanoyl)-β-D-glucosaminyl-1-phosphate 2,3-bis(3-hydroxytetradecanoyl)-glucosaminyltransferase (incorrect). Enzyme Commission Number: EC 2.4.1.182. CAS No. 105843-81-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2408; lipid-A-disaccharide synthase; EC 2.4.1.182; 105843-81-0; UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine:2,3-bis-(3-hydroxytetradecanoyl)-β-D-glucosaminyl-1-phosphate 2,3-bis(3-hydroxytetradecanoyl)-glucosaminyltransferase (incorrect). Cat No: EXWM-2408.
Lipid A (E. Coli) triethylammonium salt
Lipid A (E. Coli) triethylammonium salt is an intriguing compound with awe-inspiring aptitude to invigorate the immune system for studying infectious afflictions, predominantly focusing on pioneering vaccines and pernicious Gram-negative bacteria. Synonyms: 2-Deoxy-6-O-{2-deoxy-2-[(R)-3-(dodecanoyloxy) tetradecanoylamino]-3-O-[(R)-3-(tetradecanoyloxy) tetra decanoyl]-b-D-glucopyranosyl}-3-O-[(R)-3-hydroxy tetra decanoyl]-2-[(R)-3-hydroxy tetra decanoylamino]-a-D-glucopyranose 1,4-diphosphate triethylammonium salt; LA-15-PP diphospho hexaacyl lipid A. Molecular formula: C94H178N2O25P2. Mole weight: 1798.37.
Lipid ALC-0159
ALC-0159 is a PEG/lipid conjugate (i.e. PEGylated lipid), specifically, it is the N,N-dimyristylamide of 2-hydroxyacetic acid, O-pegylated to a PEG chain mass of about 2 kilodaltons (corresponding to about 45-46 ethylene oxide units per molecule of N,N-dimyristyl hydroxyacetamide). Synonyms: 2-[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide; ALC-0159; mPEG-N,N-Ditetradecylacetamide. Grades: ≥95%. CAS No. 1849616-42-7.
Lipid ALC-0315
ALC-0315 can be used to form lipid nanoparticle (LNP, non-viral gene delivery system). Synonyms: ALC-0315; ((4-Hydroxybutyl)azanediyl)bis(hexane-6,1-diyl) bis(2-hexyldecanoate). Grades: >98%. CAS No. 2036272-55-4. Molecular formula: C48H95NO5. Mole weight: 766.27.
Lipid A, monophosphoryl from Escherichia coli F583 (Rd mutant)
The enzyme adds one or two ethanolamine phosphate groups to lipid A giving a diphosphate, sometimes in combination with EC 2.4.2.43 (lipid IVA 4-amino-4-deoxy-L-arabinosyltransferase) giving products with 4-amino-4-deoxy-β-L-arabinose groups at the phosphates of lipid A instead of diphosphoethanolamine groups. It will also act on lipid IVA and Kdo2-lipid A. Group: Enzymes. Synonyms: lipid A PEA transferase; PmrA; LptA. Enzyme Commission Number: EC 2.7.4.30. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3213; lipid A phosphoethanolamine transferase; EC 2.7.4.30; lipid A PEA transferase; PmrA; LptA. Cat No: EXWM-3213.
Lipid A (Salmonella) triethylammonium
Lipid A (Salmonella) triethylammonium is an intricately structured derivative of Lipid A obtained from Salmonella microorganisms, facilitating comprehensive exploration and refinement of remedies pertinent to Salmonella ailments. Synonyms: 2-Deoxy-6-O- [2-deoxy-2-[(R)-3- (dodecanoyloxy) tetradecanoylamino] -3-O- [(R)-3- (tetradecanoyloxy) tetradecanoyl]- b-d-glucopyranosyl] -3-O- [(R)-3-hydroxy tetradecanoyl]- 2-[(R)-3- (hexadecanoyloxy) tetra decanoylamino]- a- d-glucopyranose 1,4-diphosphate. Molecular formula: C110H208N2O26P2. Mole weight: 2036.77.
lipid II:glycine glycyltransferase
The enzyme from Staphylococcus aureus catalyses the transfer of glycine from a charged tRNA to MurNAc-L-Ala-D-isoglutaminyl-L-Lys-D-Ala-D-Ala-diphosphoundecaprenyl-GlcNAc (lipid II), attaching it to the N6 of the L-Lys at position 3 of the pentapeptide. This is the first step in the synthesis of the pentaglycine interpeptide bridge that is used in S. aureus for the crosslinking of different glycan strands to each other. Four additional Gly residues are subsequently attached by EC 2.3.2.17 (N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-(N6-glycyl)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine:glycine glycyltransferase) and EC 2.3.2.18 (N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-(N6-triglycine)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine:glycine glycyltransferase). Group: Enzymes. Synonyms: N-acetylmuramoyl-L-alanyl-D-glu. Enzyme Commission Number: EC 2.3.2.16. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2289; lipid II:glycine glycyltransferase; EC 2.3.2.16; N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine:N6-glycine transferase; femX (gene name); alanyl-D-alanine-diphospho-ditrans,octacis-undecaprenyl-N-acetylglucosamine:glycine N6-glycyltransferase. Cat No: EXWM-2289.
LIPID In Vivo Transfection Kit
Lipid-based in vivo transfection kit. Functionally tested in mice tissue-targeted delivery of siRNA and plasmid DNA via IV,IP,IT administrations. Kit includes: Cationic lipid-based reagent. Transfection Enhancer. Protocol for mice and rats. Uses: Transfection of DNA, RNA, protein and small molecules. Group: Life Science Research Product. Product ID: 5011.
Nevada, Texas, USA
Lipid IVa
Lipid IVa is a commonly employed synthetic lipid compound in the biomedical domain, aiding in the research of lipopolysaccharides (LPS) on a myriad of ailments, including septicemia and inflammatory conditions. By unraveling the intricate dynamics of lipid signaling pathways, Lipid IVa emerges as an indispensable compound, propelling the research of LPS-induced disorders. Synonyms: Lipid A 406, LA-14-PP, Precursur 1a,; 2-Deoxy-6-O-{2-deoxy-3-O-[(R)-3-hydroxytetradecanoyl]-2-[(R)-3-hydroxytetradecanoylamino-b-D-glucopyranosyl}-3-O-[(R)-3-hydroxytetradecanoyl]-2-[(R)-3-hydroxytetradecanoylamino-a-D-glucopyranose 1,4- diphosphate. CAS No. 91841-27-9. Molecular formula: C68H130N2O23P2. Mole weight: 1405.70.
The bifunctional enzyme from Escherichia coli transfers two 3-deoxy-D-manno-oct-2-ulosonate residues to lipid IVA (cf. EC 2.4.99.13 [(Kdo)-lipid IVA 3-deoxy-D-manno-octulosonic acid transferase]). The monofunctional enzymes from Aquifex aeolicus and Hemophilus influenzae catalyse the transfer of a single 3-deoxy-D-manno-oct-2-ulosonate residue from CMP-3-deoxy-D-manno-oct-2-ulosonate to lipid IVA. The enzymes from Chlamydia transfer three or more 3-deoxy-D-manno-oct-2-ulosonate residues and generate genus-specific epitopes. Group: Enzymes. Synonyms: KDO transferase; waaA (gene name); kdtA (gene name); 3-deoxy-D-manno-oct-2-ulosonic acid transferase; 3-deoxy-manno-octulosonic acid transferase; lipid IVA KDO transferase. Enzyme Commission Number: EC 2.4.99.12. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2696; lipid IVA 3-deoxy-D-manno-octulosonic acid transferase; EC 2.4.99.12; KDO transferase; waaA (gene name); kdtA (gene name); 3-deoxy-D-manno-oct-2-ulosonic acid transferase; 3-deoxy-manno-octulosonic acid transferase; lipid IVA KDO transferase. Cat No: EXWM-2696.
lipid IVA 4-amino-4-deoxy-L-arabinosyltransferase
Integral membrane protein present in the inner membrane of certain Gram negative endobacteria. In strains that do not produce 3-deoxy-D-manno-octulosonic acid (Kdo), the enzyme adds a single arabinose unit to the 1-phosphate moiety of the tetra-acylated lipid A precursor, lipid IVA. In the presence of a Kdo disaccharide, the enzyme primarily adds an arabinose unit to the 4-phosphate of lipid A molecules. The Salmonella typhimurium enzyme can add arabinose units to both positions. Group: Enzymes. Synonyms: undecaprenyl phosphate-α-L-Ara4N transferase; 4-amino-4-deoxy-L-arabinose lipid A transferase; polymyxin resistance protein PmrK; arnT (gene name). Enzyme Commission Number: EC 2.4.2.43. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2672; lipid IVA 4-amino-4-deoxy-L-arabinosyltransferase; EC 2.4.2.43; undecaprenyl phosphate-α-L-Ara4N transferase; 4-amino-4-deoxy-L-arabinose lipid A transferase; polymyxin resistance protein PmrK; arnT (gene name). Cat No: EXWM-2672.
lipid IVA palmitoyltransferase
Isolated from the bacteria Escherichia coli and Salmonella typhimurium. The enzyme prefers phosphatidylcholine with a palmitoyl group at the sn-1 position and palmitoyl or stearoyl groups at the sn-2 position. There is some activity with corresponding phosphatidylserines but only weak activity with other diacylphosphatidyl compounds. The enzyme also acts on Kdo-(2?4)-Kdo-(2?6)-lipid IVA. Group: Enzymes. Synonyms: PagP; crcA (gene name). Enzyme Commission Number: EC 2.3.1.251. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2201; lipid IVA palmitoyltransferase; EC 2.3.1.251; PagP; crcA (gene name). Cat No: EXWM-2201.
Lipid Metabolism Compound Library
A unique collection of 496 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS). - Covers several important targets, key components in lipid metabolism pathway, such as Acetyl-CoA Carboxylase?Acyltransferase?cholesteryl ester transfer protein (CETP)?FAAH?Fatty Acid Synthase (FASN)?HMG-CoA Reductase (HMGCR), etc. - Detailed compound information with structure, target, and biological activity description. - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2510. Categories: Lipid Metabolism Compounds Libraries.