American Chemical Suppliers

A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.

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Product
Lime Terpenes Lime Terpenes. CAS No. MIXTURE. Kosher: Y. VIGON Item # 507201. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers. Vigon
America & Internationally
Limetol Limetol. CAS No. 7392-19-0. FEMA No. 3735. Kosher: Y. VIGON Item # 500913. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers. Vigon
America & Internationally
Limetol Limetol. Group: Biochemicals. Alternative Names: 2-Ethenyltetrahydro-2,6,6-trimethyl-2H-pyran; Tetrahydro-2,2,6-trimethyl-6-vinyl-2H-pyran; 2,2,6-Trimethyl-6-vinyltetrahydropyran; 2,2,6-Trimethyl-6-vinyltetrahydropyrane; 2,6,6-Trimethyl-2-vinyltetrahydro-2H-pyran; 2,6,6-Trimethyl-2-vinyltetrahydropyran; Bois de Rose oxide. Grades: Highly Purified. CAS No. 7392-19-0. Pack Sizes: 100mg. Molecular Formula: C10H18O, Molecular Weight: 154.25. US Biological Life Sciences. USBiological 3
Worldwide
Limetol Natural Limetol Natural. CAS No. 73018-51-6. Kosher: Y. VIGON Item # 503795. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers, Aromatherapy, Essetial Oils. Vigon
America & Internationally
Lime USP Lime USP. CAS No. 1305-78-8. Molecular formula: CaO. American Molecules LLC
Lime Water, Laboratory Grade, 3.8 L Storage Code: Green; general chemical storage. Grades: chem-grade laboratory. Product ID: 872443. -- SOLD FOR EDUCATIONAL USE ONLY -- Carolina Biological Supply Company
Lime Water, Laboratory Grade, 500 mL Storage Code: Green; general chemical storage. Notes: 140 mg calcium hydroxide per 100 mL of solution. Grades: chem-grade laboratory. Product ID: 872441. -- SOLD FOR EDUCATIONAL USE ONLY -- Carolina Biological Supply Company
Limiglidole Limiglidole is used as a antihyperglycaemic drug candidate. It shows antiplatelet activity 2-fold exceeded activity of antiplatelet agent acetylsalicylic acid in the mouse model of systemic collagen-epinephrine thrombosis. It significantly decreased the relative and mean area of blood clots in the sections of mouse lungs. Uses: Limiglidole is used as a antihyperglycaemic drug candidate. Synonyms: 2-(2,3-dihydro-9H-imidazo[1,2-a]benzimidazol-9-yl)-N,N-diethylethanamine. Grades: 98%. CAS No. 64644-54-8. Molecular formula: C15H22N4. Mole weight: 258.37. BOC Sciences 11
limit dextrin α-1,6-maltotetraose-hydrolase This bacterial enzyme catalyses a reaction similar to EC 3.2.1.33, amylo-α-1,6-glucosidase (one of the activities of the eukaryotic glycogen debranching enzyme). However, while EC 3.2.1.33 removes single glucose residues linked by 1,6-α-linkage, and thus requires the additional activity of 4-α-glucanotransferase (EC 2.4.1.25) to act on limit dextrins formed by glycogen phosphorylase (EC 2.4.1.1), this enzyme removes maltotriose and maltotetraose chains that are attached by 1,6-α-linkage to the limit dextrin main chain, generating a debranched limit dextrin without a need for another enzyme. Group: Enzymes. Synonyms: glgX (gene name); glycogen debranching enzyme (ambiguous). Enzyme Commission Number: EC 3.2.1.196. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3880; limit dextrin α-1,6-maltotetraose-hydrolase; EC 3.2.1.196; glgX (gene name); glycogen debranching enzyme (ambiguous). Cat No: EXWM-3880. Creative Enzymes
limit dextrinase Plant enzymes with little or no action on glycogen. Action on amylopectin is incomplete, but action on α-limit dextrins is complete. Maltose is the smallest sugar it can release from an α-(1?6)-linkage. Group: Enzymes. Synonyms: R-enzyme; amylopectin-1,6-glucosidase; dextrin α-1,6-glucanohydrolase. Enzyme Commission Number: EC 3.2.1.142. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3825; limit dextrinase; EC 3.2.1.142; R-enzyme; amylopectin-1,6-glucosidase; dextrin α-1,6-glucanohydrolase. Cat No: EXWM-3825. Creative Enzymes
LIMK1 inhibitor BMS 4 LIMK1 inhibitor BMS 4 is a potent LIM kinase 1 (LIMK1; IC50 = 22nM) inhibitor devoid of any cytotoxic side effects. Synonyms: 1-ethyl-3-[5-[6-(4-methoxy-2,6-dimethylphenyl)-2-pyrazin-2-ylpyrimidin-4-yl]-1,3-thiazol-2-yl]urea. Grades: 99%. CAS No. 905298-84-2. Molecular formula: C23H23N7O2S. Mole weight: 461.54. BOC Sciences 9
LIMKi 3 LIMKi 3. Group: Biochemicals. Grades: Purified. CAS No. 1338247-35-0. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 5
Worldwide
LIMK-IN-1 LIMK-IN-1 (Compound 14) is an inhibitor of LIM-Kinase (LIMK) , with IC 50 s of 0.5 nM and 0.9 nM for LIMK1 and LIMK2, respectively. LIMK-IN-1 can be used for ocular hypertension and associated glaucoma research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1116571-01-7. Pack Sizes: 2 mg. Product ID: HY-14227. MedChemExpress MCE
LIM Kinase Inhibitor I, LIMKi 3 (N-(5-(1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyramide) A cell-permeable pyrazolylthiazolo-isobutyramide compound that acts as a potent LIM kinase inhibitor (IC50 = 7 and 8nM against LIMK1 and LIMK2, respectively) and effectively suppresses cellular cofilin phosphorylation (IC50 ~1uM in A549 and MDA-MB-231 cultures) without affecting tubulin polymerization or inducing cytotoxicity (EC50 >10uM in A549 proliferation & colony formation assays). Shown to effectively destabilize F-actin structure in MDA-MB-231 breast cancer cells (3 to 10uM) with concomitant blockage of invasion (by 93% at 10uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 1338247-35-0. Pack Sizes: 10mg. Molecular Formula: C??H??Cl?F?N?OS. US Biological Life Sciences. USBiological 4
Worldwide
Limnonectin-1Fa Limnonectin-1Fa is an antibacterial peptide isolated from Limnonectes fujianensis. It has activity against gram-negative bacteria. Synonyms: Ser-Phe-Pro-Phe-Phe-Pro-Pro-Gly-Ile-Cys-Lys-Arg-Leu-Lys-Arg-Cys. Grades: 97.0%. Molecular formula: C89H136N24O18S2. Mole weight: 1898.3. BOC Sciences 4
Limnonectin-1Fb Limnonectin-1Fb is an antibacterial peptide isolated from Limnonectes fujianensis. It has activity against gram-negative bacteria. Synonyms: Ser-Phe-His-Val-Phe-Pro-Pro-Trp-Met-Cys-Lys-Ser-Leu-Lys-Lys-Cys. Grades: 97.9%. Molecular formula: C91H134N22O19S3. Mole weight: 1936.3. BOC Sciences 4
Limocrocin It is produced by the strain of Str. limosus. It has anti-gram-positive bacterial effect. Synonyms: (2E,4E,6E,8E,10E,12E,14E)-N1,N16-bis(2-hydroxy-5-oxocyclopent-1-en-1-yl)hexadeca-2,4,6,8,10,12,14-heptaenediamide; N,N'-Bis(2-hydroxy-5-oxo-1-cyclopentenyl)-2,4,6,8,10,12,14-hexadecaheptene-1,16-diamide; 2,4,6,8,10,12,14-Hexadecaheptaenediamide, N,N'-bis(2-hydroxy-5-oxo-1-cyclopenten-1-yl)-, (2E,4E,6E,8E,10E,12E,14E)-. CAS No. 24112-57-0. Molecular formula: C26H26N2O6. Mole weight: 462.49. BOC Sciences 5
Limone (Citrolimonin, Evodine, Dictamnolactone, Obaculactone) Limone (Citrolimonin, Evodine, Dictamnolactone, Obaculactone). Group: Biochemicals. Alternative Names: Limone; Citrolimonin; Evodine; Dictamnolactone; Obaculactone. Grades: Plant Grade. CAS No. 1180-71-8. Pack Sizes: 20mg. Molecular Formula: C26H30O8, Molecular Weight: 470.512. US Biological Life Sciences. USBiological 9
Worldwide
Limonenal Limonenal. CAS No. 6784-13-0. VIGON Item # 503272. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers, limonene aldehyde. Vigon
America & Internationally
limonene-1,2-diol dehydrogenase While the enzyme from the Gram-positive bacterium Rhodococcus erythropolis DCL14 can use both (1S,2S,4R)- and (1R,2R,4S)-menth-8-ene-1,2-diol as substrate, activity is higher with (1S,2S,4R)-menth-8-ene-1,2-diol as substrate. Group: Enzymes. Synonyms: NAD+-dependent limonene-1,2-diol dehydrogenase. Enzyme Commission Number: EC 1.1.1.297. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0206; limonene-1,2-diol dehydrogenase; EC 1.1.1.297; NAD+-dependent limonene-1,2-diol dehydrogenase. Cat No: EXWM-0206. Creative Enzymes
Limonene-1,2-epoxide Heterocyclic Organic Compound. Alternative Names: Limonene-1,2-epoxide;Limoneneoxide (mixture of isomers). CAS No. 1195-92-2. Molecular formula: C10H16O. Mole weight: 152.23344. Appearance: Colorless liquid. Density: 0.929 g/mL at 25 °C(lit.). Catalog: ACM1195922. Alfa Chemistry. 3
limonene-1,2-epoxide hydrolase Involved in the monoterpene degradation pathway of the actinomycete Rhodococcus erythropolis. The enzyme hydrolyses several alicyclic and 1-methyl-substituted epoxides, such as 1-methylcyclohexene oxide, indene oxide and cyclohexene oxide. It differs from the previously described epoxide hydrolases [EC 3.3.2.4 (trans-epoxysuccinate hydrolase), EC 3.3.2.6 (leukotriene-A4 hydrolase), EC 3.3.2.7 (hepoxilin-epoxide hydrolase), EC 3.3.2.9 (microsomal epoxide hydrolase) and EC 3.3.2.10 (soluble epoxide hydrolase)] as it is not inhibited by 2-bromo-4'-nitroacetophenone, diethyl dicarbonate, 4-fluorochalcone oxide or 1,10-phenanthroline. Both enantiomers of menth-8-ene-1,2-diol [i.e. (1R,2R,4S)-menth-8-ene-1,2-diol and (1S,2S,4R)-menth-8-ene-1,2-diol] are metabolized. Group: Enzymes. Synonyms: limonene oxide hydrolase. Enzyme Commission Number: EC 3.3.2.8. CAS No. 216503-88-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4005; limonene-1,2-epoxide hydrolase; EC 3.3.2.8; 216503-88-7; limonene oxide hydrolase. Cat No: EXWM-4005. Creative Enzymes
limonene 1,2-monooxygenase A flavoprotein (FAD). Limonene is the most widespread terpene and is formed by more than 300 plants. Rhodococcus erythropolis DCL14, a Gram-positive bacterium, is able to grow on both (S)-limonene and (R)-limonene as the sole source of carbon and energy. NADPH can act instead of NADH, although more slowly. It has not been established if the product formed is optically pure or a mixture of two enantiomers. Group: Enzymes. Enzyme Commission Number: EC 1.14.13.107. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0706; limonene 1,2-monooxygenase; EC 1.14.13.107. Cat No: EXWM-0706. Creative Enzymes
Limonene C10H16 100g Pack Size. Group: Aroma Chemicals, Biochemicals, Building Blocks, Flavours and Fragrance Materials. Formula: C10H16. CAS No. 138-86-3. Prepack ID 90027016-100g. Molecular Weight 136.23. See USA prepack pricing. Molekula Americas
Limonene Dextro Redistilled Limonene Dextro Redistilled (99%). CAS No. 5989-27-5. FEMA No. 2633. Kosher: Y. VIGON Item # 500217. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers, Aromatherapy, Essetial Oils. Vigon
America & Internationally
Limonenyltrisiloxane, 4-5 cSt Siloxane Compound. CAS No. 1263044-00-3 or 1263043-99-7. Mole weight: 358. Density: 0.88. Catalog: ACM1263044003-1. Alfa Chemistry. 4
Limonin Limonin. Group: Biochemicals. Alternative Names: (2aR, 4aR, 4bR, 5aS, 8S, 8aS, 10aR, 10bR, 14aS)-8-(3-Furanyl)decahydro-2, 2, 4a, 8a-tetramethyl-11H, 13H-oxireno[d]pyrano[4', 3':3, 3a]isobenzofuro[5, 4-f][2]benzopyran-4, 6, 13(2H, 5aH)-trione; 8-(3-Furyl)decahydro-2, 2, 4a, 8a-tetramethyl-11H, 13H-oxireno[d]pyrano[4', 3':3, 3a]isobenzofuro[5, 4-f][2]benzopyran-4, 6, 13(2H, 5aH)-trione; Limonoic Acid Di-δ-lactone; 7,16-Dioxo-7,16-dideoxylimondiol; Citrolimonin; Dictamnolactone; Evodin; Limonine; Obaculactone; [2aR-(2aα,4a β, 4bR*, 5aα, 8α, 8aα, 10aα, 10bR*, 14aα)]-8-(3-Furanyl)decahydro-2, 2, 4a, 8a-tetramethyl-11H, 13H-oxireno[d]pyrano[4', 3':3, 3a]isobenzofuro[5, 4-f][2]benzopyran-4, 6, 13(2H, 5aH)-trione. Grades: Highly Purified. CAS No. 1180-71-8. Pack Sizes: 5mg. Molecular Formula: C26H30O8, Molecular Weight: 470.51. US Biological Life Sciences. USBiological 3
Worldwide
Limonin Limonin is a triterpenoid enriched in citrus fruits, which has antivirus and antitumor ability.IC50 Value:Target: HIV; anticancerLimonin is a triterpenoid aglycone that is a bitter principle of citrus fruits. Limonin is chemically induced carcinogenesis inhibitor and HIV-1 replication inhibitor. Limonin has anti-proliferative, proapoptotic activity on several cancer cell lines and inhibits azoxymethane-induced colon cancer in rats. Limonin also inhibits HIV-1 replication in culturedf monocytes, macrophages, and mononuclear cells, perhaps by inhibition of HIV-1 protease activity. Group: Inhibitors. Alternative Names: Evodia lactone. CAS No. 1180-71-8. Molecular formula: C26H30O8. Mole weight: 470.51. Appearance: Powder. Purity: 98%+. IUPACName: (1R, 2R, 7S, 10R, 13R, 14R, 16S, 19S, 20S)-19-(Furan-3-yl)-9, 9, 13, 20-tetramethyl-4, 8, 15, 18-tetraoxahexacyclo[11.9.0.02, 7.02, 10.014, 16.014, 20]docosane-5, 12, 17-trione. Canonical SMILES: CC1 (C2CC (=O)C3 (C (C24COC (=O)CC4O1)CCC5 (C36C (O6)C (=O)OC5C7=COC=C7)C)C)C. Density: 1.39±0.1 g/cm³. Catalog: ACM1180718. Alfa Chemistry.
Limonin Limonin inhibits HIV-1 with an EC 50 of 60.0 μM. Limonin induces human colon adenocarcinoma cells apoptosis with an IC 50 of 54.74 μM. Limonin has antiviral and antitumor activities [1] [2] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Limonoic acid 3,19:16,17 dilactone. CAS No. 1180-71-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-17411. MedChemExpress MCE
Limonin Limonin - Product ID: NST-10-13. Category: Terpenes. Alternative Names: Citrolimonin, Dictamnolactone, Evodin, Limonine, Obaculactone, Obakulactone. Purity: 98%. Test method: HPLC. CAS No. 1180-71-8. Pack Sizes: 1g, 2g, 5g, 10g. Appearance: White Powder. Molecular formula: C26H30O8. Mole weight: 470.51. Storage: +2 … +8 °C. NATURE SCIENCE TECHNOLOGIES
Limonin 100mg Pack Size. Group: Aroma Chemicals, Building Blocks, Flavours and Fragrance Materials. Formula: C26H30O8. CAS No. 1180-71-8. Prepack ID 24406022-100mg. Molecular Weight 470.51. See USA prepack pricing. Molekula Americas
Limonin17-beta-D-glucopyranoside Heterocyclic Organic Compound. Alternative Names: Ccris 6986;LIMONIN GLUCOSIDE(RG). CAS No. 123564-61-4. Molecular formula: C32H42O14. Mole weight: 650.67. Catalog: ACM123564614. Alfa Chemistry. 5
limonin-D-ring-lactonase Limonoate is a triterpenoid. Group: Enzymes. Synonyms: limonin-D-ring-lactone hydrolase; limonin lactone hydrolase. Enzyme Commission Number: EC 3.1.1.36. CAS No. 9031-17-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3462; limonin-D-ring-lactonase; EC 3.1.1.36; 9031-17-8; limonin-D-ring-lactone hydrolase; limonin lactone hydrolase. Cat No: EXWM-3462. Creative Enzymes
limonoid glucosyltransferase The enzyme purified from navel orange albedo tissue also acts on the related tetranortriterpenoid nomilin. Group: Enzymes. Synonyms: uridine diphosphoglucose-limonoid glucosyltransferase. Enzyme Commission Number: EC 2.4.1.210. CAS No. 195836-82-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2438; limonoid glucosyltransferase; EC 2.4.1.210; 195836-82-9; uridine diphosphoglucose-limonoid glucosyltransferase. Cat No: EXWM-2438. Creative Enzymes
limulus clotting enzyme From the hemocyte granules of horseshoe crabs Limulus and Tachypleus. Proclotting enzyme is activated by limulus clotting factor. In peptidase family S1 (trypsin family). Group: Enzymes. Synonyms: clotting enzyme. Enzyme Commission Number: EC 3.4.21.86. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4178; limulus clotting enzyme; EC 3.4.21.86; clotting enzyme. Cat No: EXWM-4178. Creative Enzymes
limulus clotting factor B From the hemocyte granules of the horseshoe crabs Limulus and Tachypleus. Factor B is activated by limulus clotting factor C. In peptidase family S1 (trypsin family). Group: Enzymes. Enzyme Commission Number: EC 3.4.21.85. CAS No. 848851-53-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4177; limulus clotting factor B; EC 3.4.21.85; 848851-53-6. Cat No: EXWM-4177. Creative Enzymes
limulus clotting factor C From the hemocyte granules of the horseshoe crabs Limulus and Tachypleus. Factor C is activated by Gram-negative bacterial lipopolysaccharides and chymotrypsin. Inhibited by antithrombin III. In peptidase family S1 (trypsin family). Group: Enzymes. Synonyms: factor C; limulus factor C. Enzyme Commission Number: EC 3.4.21.84. CAS No. 115743-27-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4176; limulus clotting factor C; EC 3.4.21.84; 115743-27-6; factor C; limulus factor C. Cat No: EXWM-4176. Creative Enzymes
Lin28 1632 Lin28 1632 is an RNA binding protein Lin28 inhibitor with IC50 value of 8 μM. It can inhibit growth of tumor cell lines and tumor-sphere formation in vitro. Synonyms: Lin28 1632; Lin-28 1632; Lin 28 163; Lin281632; Lin-281632; Lin 281632. N-Methyl-N-[3-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)phenyl]acetamide. Grades: ≥98% by HPLC. CAS No. 108825-65-6. Molecular formula: C15H15N5O. Mole weight: 281.31. BOC Sciences 11
LIN28 inhibitor LI71 enantiomer LIN28 inhibitor LI71 enantiomer is the enantiomer of LIN28 inhibitor LI71 with less active. LIN28 inhibitor LI71 is a potent and cell-permeable LIN28 inhibitor, which abolishes LIN28-mediated oligouridylation with an IC 50 of 7 uM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 956189-58-5. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-123905A. MedChemExpress MCE
Linaclotide Linaclotide is a peptide agonist of guanylate cyclase 2C that is undergoing clinical trials for use in treating abdominal pain in patients with irritable bowel syndrome (IBS) accompanied by constipation. The drug also has promising outlooks for the treatment of gastroparesis, ulcerative colitis, chronic intestinal pseudo-obstruction (CIPO), and inertia coli as well. Synonyms: Constella; Linzess; L-Tyrosine, L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (1?6),(2?10),(5?13)-tris(disulfide); L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparagyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonyl-glycyl-L-cysteinyl-L-tyrosine (1->6),(2->10),(5->13)-tris(disulfide); H-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH (Disulfide bridge: Cys1-Cys6, Cys2-Cys10, Cys5-Cys13). Grades: ≥95%. CAS No. 851199-59-2. Molecular formula: C59H79N15O21S6. Mole weight: 1526.74. BOC Sciences 8
Linaclotide Linaclotide is a potent and selective guanylate cyclase C agonist; developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation. Uses: Scientific research. Group: Peptides. CAS No. 851199-59-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-17584. MedChemExpress MCE
Linaclotide Linaclotide. Categories: linaclotide; linzess. Pharma Resources International LLC
CA, FL & NJ
Linaclotide Linaclotide is a peptide agonist of the guanylate cyclase C receptor (Ki = 16.4nM in a radioligand binding assay using mouse intestinal mucosa).1 Luminal exposure to 5ug of linaclotide stimulates fluid secretion and cGMP concentration in jejunal loops isolated from wild-type mice but not guanylate cyclase C receptor null mice. Linaclotide (100ug/kg) increases intestinal transit in wild-type mice. It also reduces the number of phosphorylated ERK-positive dorsal horn neurons in the thoracolumbar spinal cord, a marker of nociceptive signaling, following noxious colorectal distension and mechanical hypersensitivity in a mouse model of TNBS-induced colitis.2 Formulations containing linaclotide have been used for the treatment of constipation and pain associated with irritable bowel syndrome. Group: Biochemicals. Alternative Names: L-Cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-L-tyrosine Cyclic (1?6),(2?10),(5?13)-Tris(disulfide). Grades: Highly Purified. CAS No. 851199-59-2. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C??H??N??O??S?, Molecular Weight: 1526.74. US Biological Life Sciences. USBiological 3
Worldwide
Linaclotide acetate Linaclotide is an oligo-peptide agonist of guanylate cyclase 2C. It can be used for the treatment in adults of constipation-predominant irritable bowel syndrome and chronic idiopathic constipation. Uses: Constipation; irritable bowel syndrome. Synonyms: L-Tyrosine, L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (1?6),(2?10),(5?13)-tris(disulfide), acetate (1:1); L-Tyrosine, L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (1?6),(2?10),(5?13)-tris(disulfide), monoacetate (salt); Linaclotide monoacetate; MM 416775; H-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH.CH3CO2H (Disulfide bridge: Cys1-Cys6, Cys2-Cys10, Cys5-Cys13). Grades: 95%. CAS No. 851199-60-5. Molecular formula: C61H83N15O23S6. Mole weight: 1586.80. BOC Sciences 9
Linaclotide acetate Linaclotide acetate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 851199-60-5. Molecular Formula: C61H83N15O23S6. Mole Weight: 1586.78. Catalog: APB851199605. Alfa Chemistry Analytical Products 3
Linaclotide acetate impurity 1 Linaclotide acetate impurity 1. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C59H79N15O21S6. Mole Weight: 1526.73. Catalog: APB11840. Alfa Chemistry Analytical Products 4
Linaclotide acetate impurity 2 Linaclotide acetate impurity 2. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C59H76N14O22S6. Mole Weight: 1525.7. Catalog: APB11841. Alfa Chemistry Analytical Products 4
Linaclotide acetate impurity 3 Linaclotide acetate impurity 3. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C62H84N16O22S6. Mole Weight: 1597.89. Catalog: APB11842. Alfa Chemistry Analytical Products 4
Linaclotide capsule impurity 1 Linaclotide capsule impurity 1. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C60H79N15O21S6. Mole Weight: 1538.8. Catalog: APB11820. Alfa Chemistry Analytical Products 4
Linaclotide capsule impurity 2 Linaclotide capsule impurity 2. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C60H79N15O21S6. Mole Weight: 1538.8. Catalog: APB11821. Alfa Chemistry Analytical Products 4
Linaclotide capsule impurity 3 Linaclotide capsule impurity 3. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C65H89N15O26S6. Mole Weight: 1688.9. Catalog: APB11819. Alfa Chemistry Analytical Products 4
Linagliptin A novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Group: Biochemicals. Alternative Names: 8-[(3R)-3-Amino-1-piperidinyl]-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione; 8-[(3R)-3-Amino-1-piperidinyl]-7-(2-butynyl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione; BI 1356; BI 1356BS; ONDERO. Grades: Highly Purified. CAS No. 668270-12-0. Pack Sizes: 10mg, 100mg, 500mg, 1g. Molecular Formula: C25H28N8O2, Form: Supplied as a white to orange. US Biological Life Sciences. USBiological 2
Worldwide
Linagliptin Linagliptin is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM. Group: Inhibitors. Alternative Names: Trajenta; BI-1356-BS; 8-[(3R)-3-aminopiperidin-1-yl]-7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]purine-2,6-dione; Ondero; BI-1356; Linagliptin; Tradjenta. CAS No. 668270-12-0. Molecular formula: C25H28N8O2. Mole weight: 472.54. Appearance: Solid. Purity: 95%+. IUPACName: 8-[(3R)-3-aminopiperidin-1-yl]-7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]purine-2,6-dione. Canonical SMILES: CC#CCN1C2=C (N=C1N3CCCC (C3)N)N (C (=O)N (C2=O)CC4=NC5=CC=CC=C5C (=N4)C)C. Density: 1.39. Catalog: ACM668270120. Alfa Chemistry.
Linagliptin Linagliptin is a highly potent, selective DPP-4 inhibitor with IC 50 of 1 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BI 1356. CAS No. 668270-12-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-10284. MedChemExpress MCE
Linagliptin Acetamide Linagliptin Acetamide. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-N-(1-(7-(But-2-ynyl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)acetamide,N-[(3R)-1-[7-(2-Butyn-1-yl)-2,3,6,7-tetrahydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-2,6-dioxo-1H-purin-8-yl]-3-piperidinyl]acetamide. CAS No. 1803079-49-3. Pack Sizes: 10MG. IUPAC Name: N-[(3R)-1-[7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-2,6-dioxopurin-8-yl]piperidin-3-yl]acetamide. Molecular Formula: C27H30N8O3. Mole Weight: 514.58. Catalog: APS1803079493. SMILES: CC#CCn1c (nc2N (C)C (=O)N (Cc3nc (C)c4ccccc4n3)C (=O)c12)N5CCC[C@H] (C5)NC (=O)C. Format: Neat. Shipping: Room Temperature. Alfa Chemistry Analytical Products
Linagliptin Acetamide-d3 Linagliptin Acetamide-d3 is the isotope labelled analog of Linagliptin Acetamide. Linagliptin Acetamide is an impurity of linagliptin, which is a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Group: Biochemicals. Alternative Names: (R)-N-(1-(7-(But-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)acetamide-d3. Grades: Highly Purified. CAS No. 1297274-00-0. Pack Sizes: 1mg, 2.5mg, 5mg. Molecular Formula: C27H27D3N8O3. US Biological Life Sciences. USBiological 9
Worldwide
Linagliptin Des-Piperidine amine An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Synonyms: Linagliptin J; 1H-Purine-2,6-dione, 7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-. Grades: ≥95%. CAS No. 1911621-52-7. Molecular formula: C20H18N6O2. Mole weight: 374.40. BOC Sciences 8
Linagliptin Diene Impurity an impurity in the synthesis of Linagliptin. Synonyms: Des-(N-butyn-1-yl) N-(Buta-1,2-Dien-1-yl) Linagliptin; 8-((R)-3-Aminopiperidin-1-yl)-7-(buta-1,2-dien-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione. Grades: > 95%. Molecular formula: C25H28N8O2. Mole weight: 472.54. BOC Sciences 6
Linagliptin Dimer Impurity 2 Cas No. 1418133-47-7. BOC Sciences 6
Linagliptin Dimer Impurity 3 Grades: > 95%. Molecular formula: C52H60N16O4. Mole weight: 973.16. BOC Sciences 6
Linagliptin Dimer Impurity 5 Grades: > 95%. Molecular formula: C60H62N18O4. Mole weight: 1099.28. BOC Sciences 6
Linagliptin Impurity Linagliptin Impurity, is a new potent DPP-4 inhibitors structurally derived form the xanthine scaffold for the treatment of type 2 diabetes. Synonyms: (R)-7-(But-2-yn-1-yl)-3-methyl-8-(3-(((4-methylquinazolin-2-yl)methyl)amino)piperidin-1-yl)-1H-purine-2,6(3H,7H)-dione. Grades: > 95%. Molecular formula: C25H28N8O2. Mole weight: 472.54. BOC Sciences 6
Linagliptin impurity 1 Linagliptin impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2138805-26-0. Molecular Formula: C25H29ClN8O2. Mole Weight: 509.01. Catalog: APB2138805260. Alfa Chemistry Analytical Products 2
Linagliptin impurity 10 Linagliptin impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 586408-08-4. Molecular Formula: C10H10N4O2. Mole Weight: 218.22. Catalog: APB586408084. Alfa Chemistry Analytical Products 2
Linagliptin Impurity 10 Linagliptin Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-8-(3-aminopiperidin-1-yl)-3-methyl-7-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione. Molecular Formula: C21H24N8O2. Mole Weight: 420.47. Catalog: APB01613. Alfa Chemistry Analytical Products 4
Linagliptin Impurity 10 (S-Isomer) a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Synonyms: (S)-Linagliptin; 8-[(3S)-3-Amino-1-piperidinyl]-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione. Grades: > 95%. CAS No. 668270-11-9. Molecular formula: C25H28N8O2. Mole weight: 472.55. BOC Sciences 8
Linagliptin Impurity 11 Grades: > 95%. Molecular formula: C25H28N8O2. Mole weight: 472.55. BOC Sciences 6
Linagliptin Impurity 12 Grades: > 95%. Molecular formula: C31H38N8O7. Mole weight: 634.70. BOC Sciences 6
Linagliptin Impurity 13 Grades: > 95%. Molecular formula: C20H18BrN5O4. Mole weight: 472.30. BOC Sciences 6
Linagliptin impurity 14 Grades: > 95%. Molecular formula: C45H44N14O4. Mole weight: 844.94. BOC Sciences 6

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