A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Linaclotide is a peptide agonist of guanylate cyclase 2C that is undergoing clinical trials for use in treating abdominal pain in patients with irritable bowel syndrome (IBS) accompanied by constipation. The drug also has promising outlooks for the treatment of gastroparesis, ulcerative colitis, chronic intestinal pseudo-obstruction (CIPO), and inertia coli as well. Synonyms: Constella; Linzess; L-Tyrosine, L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (1?6),(2?10),(5?13)-tris(disulfide); L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparagyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonyl-glycyl-L-cysteinyl-L-tyrosine (1->6),(2->10),(5->13)-tris(disulfide); H-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH (Disulfide bridge: Cys1-Cys6, Cys2-Cys10, Cys5-Cys13). Grades: ≥95%. CAS No. 851199-59-2. Molecular formula: C59H79N15O21S6. Mole weight: 1526.74.
Linaclotide
Linaclotide is a potent and selective guanylate cyclase C agonist; developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation. Uses: Scientific research. Group: Peptides. CAS No. 851199-59-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-17584.
Linaclotide acetate
Linaclotide is an oligo-peptide agonist of guanylate cyclase 2C. It can be used for the treatment in adults of constipation-predominant irritable bowel syndrome and chronic idiopathic constipation. Uses: Constipation; irritable bowel syndrome. Synonyms: L-Tyrosine, L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (1?6),(2?10),(5?13)-tris(disulfide), acetate (1:1); L-Tyrosine, L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (1?6),(2?10),(5?13)-tris(disulfide), monoacetate (salt); Linaclotide monoacetate; MM 416775; H-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH.CH3CO2H (Disulfide bridge: Cys1-Cys6, Cys2-Cys10, Cys5-Cys13). Grades: 95%. CAS No. 851199-60-5. Molecular formula: C61H83N15O23S6. Mole weight: 1586.80.
Linagliptin
Linagliptin is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Trajenta; BI-1356-BS; 8-[(3R)-3-aminopiperidin-1-yl]-7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]purine-2,6-dione; Ondero; BI-1356; Linagliptin; Tradjenta. Product Category: Inhibitors. Appearance: Solid. CAS No. 668270-12-0. Molecular formula: C25H28N8O2. Mole weight: 472.54. Purity: 95%+. IUPACName: 8-[(3R)-3-aminopiperidin-1-yl]-7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]purine-2,6-dione. Canonical SMILES: CC#CCN1C2=C(N=C1N3CCCC(C3)N)N(C(=O)N(C2=O)CC4=NC5=CC=CC=C5C(=N4)C)C. Density: 1.39. Product ID: ACM668270120. Alfa Chemistry ISO 9001:2015 Certified.
Linagliptin
Linagliptin is a highly potent, selective DPP-4 inhibitor with IC 50 of 1 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BI 1356. CAS No. 668270-12-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-10284.
A novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Group: Biochemicals. Alternative Names: 8-[(3R)-3-Amino-1-piperidinyl]-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione; 8-[(3R)-3-Amino-1-piperidinyl]-7-(2-butynyl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione; BI 1356; BI 1356BS; ONDERO. Grades: Highly Purified. CAS No. 668270-12-0. Pack Sizes: 10mg, 100mg, 500mg, 1g. Molecular Formula: C25H28N8O2, Form: Supplied as a white to orange. US Biological Life Sciences.
Worldwide
Linagliptin Acetamide
Linagliptin Acetamide. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-N-(1-(7-(But-2-ynyl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)acetamide,N-[(3R)-1-[7-(2-Butyn-1-yl)-2,3,6,7-tetrahydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-2,6-dioxo-1H-purin-8-yl]-3-piperidinyl]acetamide. CAS No. 1803079-49-3. Pack Sizes: 10MG. IUPAC Name: N-[(3R)-1-[7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-2,6-dioxopurin-8-yl]piperidin-3-yl]acetamide. Molecular formula: C27H30N8O3. Mole weight: 514.58. Catalog: APS1803079493. SMILES: CC#CCn1c(nc2N(C)C(=O)N(Cc3nc(C)c4ccccc4n3)C(=O)c12)N5CCC[C@H](C5)NC(=O)C. Format: Neat. Shipping: Room Temperature.
Linagliptin Acetamide-d3
Linagliptin Acetamide-d3 is the isotope labelled analog of Linagliptin Acetamide. Linagliptin Acetamide is an impurity of linagliptin, which is a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Group: Biochemicals. Alternative Names: (R)-N-(1-(7-(But-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)acetamide-d3. Grades: Highly Purified. CAS No. 1297274-00-0. Pack Sizes: 1mg, 2.5mg, 5mg. Molecular Formula: C27H27D3N8O3. US Biological Life Sciences.
Worldwide
Linagliptin Des-Piperidine amine
An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Synonyms: Linagliptin J; 1H-Purine-2,6-dione, 7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-. Grades: ≥95%. CAS No. 1911621-52-7. Molecular formula: C20H18N6O2. Mole weight: 374.40.
Linagliptin Diene Impurity
an impurity in the synthesis of Linagliptin. Synonyms: Des-(N-butyn-1-yl) N-(Buta-1,2-Dien-1-yl) Linagliptin; 8-((R)-3-Aminopiperidin-1-yl)-7-(buta-1,2-dien-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione. Grades: > 95%. Molecular formula: C25H28N8O2. Mole weight: 472.54.
Linagliptin Impurity, is a new potent DPP-4 inhibitors structurally derived form the xanthine scaffold for the treatment of type 2 diabetes. Synonyms: (R)-7-(But-2-yn-1-yl)-3-methyl-8-(3-(((4-methylquinazolin-2-yl)methyl)amino)piperidin-1-yl)-1H-purine-2,6(3H,7H)-dione. Grades: > 95%. Molecular formula: C25H28N8O2. Mole weight: 472.54.
Linagliptin Impurity 10 (S-Isomer)
a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Synonyms: (S)-Linagliptin; 8-[(3S)-3-Amino-1-piperidinyl]-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione. Grades: > 95%. CAS No. 668270-11-9. Molecular formula: C25H28N8O2. Mole weight: 472.55.
An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Synonyms: 8-Bromo-3-methyl-1,7-bis((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione; 1H-Purine-2,6-dione, 8-bromo-3,7-dihydro-3-methyl-1,7-bis[(4-methyl-2-quinazolinyl)methyl]-; 8-Bromo-3,7-dihydro-3-methyl-1,7-bis[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione. Grades: ≥95%. CAS No. 2138392-83-1. Molecular formula: C26H21BrN8O2. Mole weight: 557.41.
An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Synonyms: Des-(R)-piperidin-3-amine 8-(R)-(Piperidin-3-ylamino) Linagliptin; (R)-7-(but-2-ynyl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-8-(piperidin-3-ylamino)-1H-purine-2,6(3H,7H)-dione. CAS No. 1446263-38-2. Molecular formula: C25H28N8O2. Mole weight: 472.5.
Linagliptin Impurity F
Linagliptin Impurity F. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-N-(1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)-2,2,2-trifluoroacetamide. CAS No. 1673546-62-7. Molecular formula: C27H27F3N8O3. Mole weight: 568.55. Catalog: APB1673546627.
An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Grades: ≥95%. Molecular formula: C25H29N7O4. Mole weight: 491.55.
Linagliptin impurity KH-3
An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Synonyms: tert-butyl (R)-(1-(1-(2-((2-acetylphenyl)amino)-2-oxoethyl)-7-(but-2-yn-1-yl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate; (R)-tert-Butyl (1-(1-(2-((2-acetylphenyl)amino)-2-oxoethyl)-7-(but-2-yn-1-yl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate. Grades: ≥95%. CAS No. 2279114-27-9. Molecular formula: C30H37N7O6. Mole weight: 591.66.
An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Grades: ≥95%. Molecular formula: C25H27N7O3. Mole weight: 473.54.
Linagliptin Impurity S
an impurity of Linagliptin. Synonyms: N-Des-(2-butyn-1-yl)-N-(3-bromo-2-buten-1-yl) Linagliptin (E/Z Mixture); 8-[(3R)-3-Amino-1-piperidinyl]-7-[(2E/Z)-3-bromo-2-buten-1-yl]-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione. Grades: > 95%. Molecular formula: C25H29BrN8O2. Mole weight: 553.47.
Linagliptin Impurity SIM
An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Grades: ≥95%. Molecular formula: C26H21BrN8O2. Mole weight: 557.41.
Linagliptin Impurity SQBOC
An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Grades: ≥95%. Molecular formula: C24H32N6O4. Mole weight: 468.56.
Linagliptin Impurity XDBoc
An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Grades: ≥95%. Molecular formula: C30H37BrN8O4. Mole weight: 653.58.
Linagliptin Impurity YYJ
An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Synonyms: 7-(But-2-yn-1-yl)-8-ethoxy-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione (Linagliptin Impurity); Linagliptin Impurity YYJ. Grades: ≥95%. CAS No. 1803079-48-2. Molecular formula: C22H22N6O3. Mole weight: 418.46.
Linagliptin Metabolite CD1790
an impurity in the synthesis of Linagliptin. Synonyms: 3-Deamino 3-Hydroxy Linagliptin; (S)-7-(But-2-yn-1-yl)-8-(3-hydroxypiperidin-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione. Grades: > 95%. Molecular formula: C25H27N7O3. Mole weight: 473.54.
Linagliptin Methyldimer
An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Synonyms: 8-[(3R)-3-Amino-1-piperidinyl]-1-[[4-[[2-[[8-[(3R)-3-amino-1-piperidinyl]-7-(2-butyn-1-yl)-2,3,6,7-tetrahydro-3-methyl-2,6-dioxo-1H-purin-1-yl]methyl]-1,4-dihydro-4-methyl-4-quinazolinyl]methyl]-2-quinazolinyl]methyl]-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1H-purine-2,6-dione; 8-((R)-3-Aminopiperidin-1-yl)-1-((4-((2-((8-((R)-3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)methyl)-4-methyl-1,4-dihydroquinazolin-4-yl)methyl)quinazolin-2-yl)methyl)-7-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione; Linagliptin Dimer Impurity. Grades: > 95%. CAS No. 1418133-47-7. Molecular formula: C50H56N16O4. Mole weight: 945.08.
Linagliptin N-Acetyl Impurity
An impurity of Linagliptin. Linagliptin is a dipeptidyl peptidase-4 inhibitor with a hpyerglycemic activity. It was approved for the treatment of diabetes mellitus type 2. Synonyms: (R)-N-(1-(7-(But-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)acetamide. Grades: 95%. CAS No. 1803079-49-3. Molecular formula: C27H30N8O3. Mole weight: 514.58.
Linagliptin N-Boc Impurity
An impurity of Linagliptin. Linagliptin is a dipeptidyl peptidase-4 inhibitor with a hpyerglycemic activity. It was approved for the treatment of diabetes mellitus type 2. Synonyms: Linagliptin Related Compound B, N-[(3R)-1-[7-(2-butyn-1-yl)-2,3,6,7-tetrahydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-2,6-dioxo-1H-purin-8-yl]-3-piperidinyl]-carbamic Acid 1,1-Dimethylethyl Ester. Grades: 95%. CAS No. 668273-75-4. Molecular formula: C30H36N8O4. Mole weight: 572.67.
Linagliptin N-Formyl Impurity
An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Synonyms: Linagliptin Impurity JX; (R)-N-(1-(7-(But-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)formamide. Grades: ≥95%. CAS No. 2137744-33-1. Molecular formula: C26H28N8O3. Mole weight: 500.55.
Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 78-70-6. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-N0368.
Linalool
Linalool (CAS# 78-70-6) is a useful research chemical. Synonyms: 3,7-dimethylocta-1,6-dien-3-ol. Grades: > 98 %. CAS No. 78-70-6. Molecular formula: C10H18O. Mole weight: 154.25.
Linalool
500g Pack Size. Group: Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials. Formula: C10H18O. CAS No. 78-70-6. Prepack ID 17547483-500g. Molecular Weight 154.25. See USA prepack pricing.
Linalool
Linalool. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,6-Dimethyl-2,7-octadiene-6-ol. Product Category: Alkenes. Appearance: Liquid. CAS No. 78-70-6. Molecular formula: C10H18O. Mole weight: 154.25. Purity: 0.96. IUPACName: 3,7-Dimethylocta-1,6-dien-3-ol. Canonical SMILES: CC(=CCCC(C)(C=C)O)C. Density: 0.87 g/mL at 25 °C(lit.). Product ID: ACM78706. Alfa Chemistry ISO 9001:2015 Certified.
Linalool
Linalool is a naturally occurring terpene alcohol chemical found in many flowers and spice plants with many commercial applications, the majority of which are based on its pleasant scent (floral, with a touch of spiciness). Linalool is used as a scent in 60-80% of perfumed hygiene products and cleaning agents including soaps, detergents, shampoos, and lotions. Group: Biochemicals. Alternative Names: 3,7-Dimethyl-1,6-octadien-3-ol; (±)-Linalool; 2,6-Dimethyl-2,7-octadien-6-ol; 2-Methyl-1-prenyl-3-buten-2-ol; 3,7-Dimethyl-1,6-octadien-3-ol; 3,7-Dimethyl-1,6-octadiene-3-ol; 3,7-Dimethyl-3-hydroxy-1,6-octadiene; 3,7-Dimethyl-3-ol-1,6-octadiene; L 260-2; Linalol; Linalyl Alcohol; Linanool; NSC 3789; dl-Linalool; β-Linalool. Grades: Highly Purified. CAS No. 78-70-6. Pack Sizes: 100g, 250g, 500g. Molecular Formula: C??H??O, Molecular Weight: 154.25. US Biological Life Sciences.
Worldwide
linalool 8-monooxygenase
A heme-thiolate protein (P-450). The secondary electron donor is a specific [2Fe-2S] ferredoxin from the same bacterial strain. Group: Enzymes. Synonyms: P-450lin; CYP111. Enzyme Commission Number: EC 1.14.13.151. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0751; linalool 8-monooxygenase; EC 1.14.13.151; P-450lin; CYP111. Cat No: EXWM-0751.
Linalool 98% GC
Linalool 98% GC.
CA, FL & NJ
linalool dehydratase
In absence of oxygen the bifunctional linalool dehydratase-isomerase can catalyse in vitro two reactions, the hydration of myrcene to (3S)-linalool and the isomerization of (3S)-linalool to geraniol, the latter activity being classified as EC 5.4.4.4, geraniol isomerase. Group: Enzymes. Synonyms: linalool hydro-lyase (myrcene-forming). Enzyme Commission Number: EC 4.2.1.127. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4968; linalool dehydratase; EC 4.2.1.127; linalool hydro-lyase (myrcene-forming). Cat No: EXWM-4968.
Linalool Natural ex Bois de Rose
Linalool Natural ex Bois de Rose. CAS No. 78-70-6. FEMA No. 2635. Kosher: Y. VIGON Item # 500970. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers, Aromatherapy, Essetial Oils.
America & Internationally
Linalool Natural ex Ho
Linalool Natural ex Ho. CAS No. 78-70-6. FEMA No. 2635. Kosher: Y. VIGON Item # 500769. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers, Aromatherapy, Essetial Oils.
America & Internationally
Linalool oxide
Linalool oxide is a secondary metabolite in elongating wheat plants with antinociceptive and anticonvulsant effects. Linalool oxide shows anxiolytic activity [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 60047-17-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-N9502.
Linalyl acetate is the principal components of many plant essential oils with potentially anti-inflammatory activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 115-95-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-N6948.
Linalyl Acetate
Linalyl Acetate. Group: Biochemicals. Alternative Names: Linalool acetate. Grades: Plant Grade. CAS No. 115-95-7. Pack Sizes: 20mg. Molecular Formula: C12H20O2, Molecular Weight: 196.286. US Biological Life Sciences.