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Neuromedin n. Uses: Designed for use in research and industrial production. Additional or Alternative Names: H-LYS-ILE-PRO-TYR-ILE-LEU-OH;LYS-ILE-PRO-TYR-ILE-LEU;KIPYIL;NEUROKININ N;NEUROMEDIN N;NEUROMEDIN N (PORCINE);NEUROMEDIN N (RAT, MOUSE, PORCINE, CANINE);L-Lys-L-Ile-L-Pro-L-Tyr-L-Ile-L-Leu-OH. Product Category: Heterocyclic Organic Compound. CAS No. 92169-45-4. Molecular formula: C38H63N7O8. Mole weight: 745.95. Product ID: ACM92169454. Alfa Chemistry ISO 9001:2015 Certified.
Neuromedin N
Neuromedin N is an intricate peptide extensively investigated within the biomedical arena, offering profound insights into its multifaceted involvement in studying diverse neurological disorders. Acting upon distinct receptors both in the central nervous system and peripheral tissues, this product exhibits the potential to exert considerable impact on the modulation of neuronal activity. Synonyms: Neuromedin N; Lys-ile-pro-tyr-ile-leu; 102577-25-3; 92169-45-4; Lysyl-isoleucyl-prolyl-tyrosyl-isoleucyl-leucine; Neuromedin N (rat, mouse, porcine, canine); H-Lys-Ile-Pro-Tyr-Ile-Leu-OH; NmN-125; CHEMBL1558364; DTXSID20145280; HY-P0079; AKOS024456846; CS-5506; NCGC00167134-01; MS-31303; Q7002397; (2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-1-[(2S,3S)-2-[[(2S)-2,6-diaminohexanoyl]amino]-3-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid; (S)-2-((2S,3S)-2-((S)-2-((S)-1-((2S,3S)-2-((S)-2,6-diaminohexanamido)-3-methylpentanoyl)pyrrolidine-2-carboxamido)-3-(4-hydroxyphenyl)propanamido)-3-methylpentanamido)-4-methylpentanoic acid. Grades: 95%. CAS No. 102577-25-3. Molecular formula: C38H63N7O8. Mole weight: 745.9.
Neuromedin N
Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes. Uses: Scientific research. Group: Peptides. Alternative Names: Neuromedin N (rat, mouse, porcine, canine). CAS No. 92169-45-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-P0079.
Neuromedin N acetate
Neuromedin N acetate is a potent modulator of dopamine D2 receptor agonist which binds in rat neostriatal membranes. Synonyms: H-Lys-Ile-Pro-Tyr-Ile-Leu-OH.CH3CO2H; L-lysyl-L-isoleucyl-L-prolyl-L-tyrosyl-L-isoleucyl-L-leucine acetic acid; Canine neuromedin N acetate salt; Mouse neuromedin N acetate salt; Neuromedin N (dog) acetate salt; Neuromedin N (human) acetate salt; Neuromedin N (ox) acetate salt; Neuromedin N (rat) acetate salt; Porcine neuromedin N acetate salt; Neuromedin N (rat, mouse, porcine, canine) acetate. Grades: ≥95%. Molecular formula: C40H67N7O10. Mole weight: 806.02.
Neuromedin S (human)
Neuromedin S (NMS), a 33-amino acid neuropeptide originally isolated from the rat brain, is a neuromedin U (NMU) receptor as an endogenous ligand of two orphan G protein-coupled receptors FM-3/GPR66 and FM-4/TGR-1. hNMS-33 is specifically expressed in the suprachiasmatic nuclei (SCN) of the hypothalamus. NMS is involved in circadian rhythm regulation through autocrine and/or paracrine. Synonyms: NMS (human); H-Ile-Leu-Gln-Arg-Gly-Ser-Gly-Thr-Ala-Ala-Val-Asp-Phe-Thr-Lys-Lys-Asp-His-Thr-Ala-Thr-Trp-Gly-Arg-Pro-Phe-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2; hNMS-33. Grades: ≥95%. CAS No. 1138204-27-9. Molecular formula: C173H265N53O44. Mole weight: 3791.34.
Neuromedin S (rat)
Neuromedin S, a novel neuropeptide of 36 amino acids isolated from rat brain as an endogenous ligand for the orphan G protein-coupled receptors FM-3/GPR66 and FM-4/TGR-1, is a potent, endogenous neuromedin U receptor agonist (EC50 values are 65 and 91 pM at NMU1 and NMU2 respectively). Central NMS may exert a physiological antidiuretic action via vasopressin release. Synonyms: L-leucyl-L-prolyl-L-arginyl-L-leucyl-L-leucyl-L-histidyl-L-threonyl-L-α-aspartyl-L-seryl-L-arginyl-L-methionyl-L-alanyl-L-threonyl-L-isoleucyl-L-α-aspartyl-L-phenylalanyl-L-prolyl-L-lysyl-L-lysyl-L-α-aspartyl-L-prolyl-L-threonyl-L-threonyl-L-seryl-L-leucylglycyl-L-arginyl-L-prolyl-L-phenylalanyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-arginyl-L-prolyl-L-arginyl-L-aspartamide, trifluoroacetate salt; Leu-Pro-Arg-Leu-Leu-His-Thr-Asp-Ser-Arg-Met-Ala-Thr-Ile-Asp-Phe-Pro-Lys-Lys-Asp-Pro-Thr-Thr-Ser-Leu-Gly-Arg-Pro-Phe-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2. CAS No. 843782-19-4. Molecular formula: C193H307N57O49S. Mole weight: 4241.97.
Neuromedin U-25 (NMU-25) is a 25-amino acid neuropeptide found in CNS of humans, demonstrated to drive smooth muscle contraction and regulate blood pressure. In vivo study has shown that it regulates feeding, vasoconstriction, nociception, and bone remodeling and contributes to obesity, cancer and septic shock. Synonyms: NMU-25 (human); H-Phe-Arg-Val-Asp-Glu-Glu-Phe-Gln-Ser-Pro-Phe-Ala-Ser-Gln-Ser-Arg-Gly-Tyr-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2; L-Aspartamide, L-phenylalanyl-L-arginyl-L-valyl-L-α-aspartyl-L-α-glutamyl-L-α-glutamyl-L-phenylalanyl-L-glutaminyl-L-seryl-L-prolyl-L-phenylalanyl-L-alanyl-L-seryl-L-glutaminyl-L-seryl-L-arginylglycyl-L-tyrosyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-arginyl-L-prolyl-L-arginyl-. Grades: ≥98%. CAS No. 312306-89-1. Molecular formula: C141H203N41O38. Mole weight: 3080.37.
Neuromedin U-25, from porcine spinal cord, is a potent stimulator of the smooth muscle of the rat uterus, and affects blood pressure in rats and dogs. Neuromedin U-8 is the same as Neuromedin U-25. Synonyms: Neuromedin u 25 (swinespinal cord); H-Phe-Lys-Val-Asp-Glu-Glu-Phe-Gln-Gly-Pro-Ile-Val-Ser-Gln-Asn-Arg-Arg-Tyr-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2; L-phenylalanyl-L-lysyl-L-valyl-L-alpha-aspartyl-L-alpha-glutamyl-L-alpha-glutamyl-L-phenylalanyl-L-glutaminyl-glycyl-L-prolyl-L-isoleucyl-L-valyl-L-seryl-L-glutaminyl-L-asparagyl-L-arginyl-L-arginyl-L-tyrosyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-arginyl-L-prolyl-L-arginyl-L-asparaginamide; Neuromedin U-25 (porcine); NMU-25. Grades: ≥95%. CAS No. 98395-76-7. Molecular formula: C144H217N43O37. Mole weight: 3142.53.
Neuromedin U-25 (porcine)
Neuromedin U-25 (porcine) is a uterus stimulating and hypertensive peptides [1]. Uses: Scientific research. Group: Peptides. CAS No. 98395-76-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4682.
Neuromedin (U8), porcine
Neuromedin (U8), porcine has potent agonist activity for neuromedin resceptors NMUR1 and NMUR2. Synonyms: Neuromedin U-8; L-tyrosyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-arginyl-L-prolyl-L-arginyl-L-asparaginamide; H-Tyr-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2. Grades: 95% by HPLC. CAS No. 98395-75-6. Molecular formula: C54H78N16O10. Mole weight: 1111.30.
Neuromedin u(rat)
Neuromedin u(rat). Uses: Designed for use in research and industrial production. Additional or Alternative Names: NEUROMEDIN U (RAT);NMU-23 (RAT);NMU, RAT;YKVNEYQGPVAPSGGFFLFRPRN-NH2;TYR-LYS-VAL-ASN-GLU-TYR-GLN-GLY-PRO-VAL-ALA-PRO-SER-GLY-GLY-PHE-PHE-LEU-PHE-ARG-PRO-ARG-ASN-NH2;H-TYR-LYS-VAL-ASN-GLU-TYR-GLN-GLY-PRO-VAL-ALA-PRO-SER-GLY-GLY-PHE-PHE-LEU-PHE-ARG-PRO-ARG. Product Category: Heterocyclic Organic Compound. CAS No. 117505-80-3. Molecular formula: C124H180N34O31. Mole weight: 2642.97. Product ID: ACM117505803. Alfa Chemistry ISO 9001:2015 Certified.
Neuromedin U, rat
Neuromedin U, a structurally highly conserved neuropeptide, is ubiquitously distributed, with highest levels found in the gastrointestinal tract and pituitary. Neuromedin U regulates blood pressure, ion transport in the gut, mesenteric blood flow and adrenocortical function, and also decreases food intake and body weight, increases body temperature and heat production, and inhibits gastric acid secretion via the CRH system following central administration in vivo. Synonyms: Rat neuromedin U-23; H-Tyr-Lys-Val-Asn-Glu-Tyr-Gln-Gly-Pro-Val-Ala-Pro-Ser-Gly-Gly-Phe-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2; L-tyrosyl-L-lysyl-L-valyl-L-asparagyl-L-alpha-glutamyl-L-tyrosyl-L-glutaminyl-glycyl-L-prolyl-L-valyl-L-alanyl-L-prolyl-L-seryl-glycyl-glycyl-L-phenylalanyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-arginyl-L-prolyl-L-arginyl-L-asparaginamide. Grades: ≥95%. CAS No. 117505-80-3. Molecular formula: C124H180N34O31. Mole weight: 2642.97.
Neuronal Differentiation Inducer III - CAS 832115-62-5
A cell-permeable isoxazole compound that selectively induces robust neuronal differentiation (Effective concentration = 20 μM) in various stem/progenitor cells. Group: Fluorescence/luminescence spectroscopy.
Neuronal Differentiation Inducer, Isobavachin
A cell-permeable, 8-prenyl flavone that is shown to induce differentiation of mouse embryonic stem (ES) cells into neuronal cells and astrocytes, at 100 nM. Group: Fluorescence/luminescence spectroscopy.
A cell-permeable, 8-prenyl flavone that is shown to induce differentiation of mouse embryonic stem (ES) cells into neuronal cells and astrocytes, at 100nM. It is shown to elicit the down-regulation of p38 and JNK phosphorylation, and the up-regulation of ERK phosphorylation. Co-treatment with GGTI-298 (1000nM), a Geranyl geranyl transferase I Inhibitor selectively abolishes the IBA- but not Retinoic Acid-induced neuronal differentiation, which suggests that the differentiation inducing effect may involve protein prenylation. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Neuronal Differentiation Inducer IV
A cell-permeable quinoxaline compound that is shown to induce neuronal differentiation in PC12 and rat MSC (mesenchymal stem cell) cultures with high efficiency. Group: Fluorescence/luminescence spectroscopy.
Neuronal Differentiation Inducer IV (N-Hydroxy-2-oxo-3-(3-phenylpropyl)-1,2-dihydroquinoxaline-6-carboxamide, 2-Oxo-3-(3-phenyl-propyl)-1,2-dihydro-quinoxaline-6-carboxylic Acid Hydroxyamide)
A cell-permeable quinoxaline compound that is shown to induce neuronal differentiation in PC12 and rat MSC (mesenchymal stem cell) cultures with high efficiency (>95%; 20uM for 48h) as determined by Nissl staining, expressions of neuronal markers and genes (B-III tubulin, NSE, Chrna2, Chrnb2, Chrm4, Foxo2, Sizn 1), as well as by whole-cell electrophysiology measurements, without any concomitant astroglial differentiation induction as indicated by the absence of GFAP (glial fibrillary acidic protein) expression. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Neuronal Signaling Compound Library
A unique collection of 2011 compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs; - Bioactivity and safety confirmed by pre-clinical research and clinical trials; - Targets include 5-HT receptor, AChR, Histamine receptor, dopamine receptor, Opioid receptor, etc; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2600. Categories: Neuronal Signaling Compounds Libraries.
Neuronal Specific Enolase (His Tag) from Human, Recombinant
NSE is the γ isoform of the glycolytic enzyme enolase and is expressed primarily in neurons, in normal and neoplastic neuroendocrine cells. NSE is a highly soluble cytoplasmic protein that is readily secreted into the CSF and serum following tissue damage. NSE shows neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons and binds in a calcium-dependent manner to cultured neocortical neurons promoting cell survival. Neuron specific enolase human recombinant is expressed in e. coli containing 433 amino acids 2-434 fused to an amino terminal hexahistidine tag. the nse is purified by proprietary chromatographic ...y: Greater than 95% as determined by SDS-PAGE. Single band on Western Blot. Enolase. Stability: Store at 4°C if entire vial will be used within 1-2 weeks. Store, frozen at -20°C for longer periods of time. Please prevent freeze-thaw cycles. Appearance: Sterile Filtered clear solution. Source: E. coli. Species: Human. EC 4.2.1.11; Neuron Specific Enolase; NSE; enolase; 2-phosphoglycerate dehydratase; 14-3-2-protein; nervous-system specific enolase; phosphoenolpyruvate hydratase; 2-phosphoglycerate dehydratase; 2-phosphoglyceric dehydratase; 2-phosphoglycerate enolase; γ-enolase; 2-phospho-D-glycerate hydro-lyase; phosphopyruvate hydratase. Cat No: NATE-0903.
Neuropeptide AF, an endogenous anti-opioid peptide involved in pain modulation and endocrine functions, may also regulate metabolism via stimulation of β-adrenoceptor expression in adipocytes. Synonyms: Neuropeptide AF (human); H-Ala-Gly-Glu-Gly-Leu-Asn-Ser-Gln-Phe-Trp-Ser-Leu-Ala-Ala-Pro-Gln-Arg-Phe-NH2; L-alanyl-glycyl-L-alpha-glutamyl-glycyl-L-leucyl-L-asparagyl-L-seryl-L-glutaminyl-L-phenylalanyl-L-tryptophyl-L-seryl-L-leucyl-L-alanyl-L-alanyl-L-prolyl-L-glutaminyl-L-arginyl-L-phenylalaninamide. Grades: ≥95%. CAS No. 192387-38-5. Molecular formula: C90H132N26O25. Mole weight: 1978.17.
Neuropeptide EI, rat
Neuropeptide EI, rat exhibits functional melanin-concentrating hormone (MCH) antagonist and melanocyte-stimulating hormone (MSH) agonist activities under different behavioral patterns. Synonyms: Neuropeptide EI (human, mouse, rat); H-Glu-Ile-Gly-Asp-Glu-Glu-Asn-Ser-Ala-Lys-Phe-Pro-Ile-NH2; L-alpha-glutamyl-L-isoleucyl-glycyl-L-alpha-aspartyl-L-alpha-glutamyl-L-alpha-glutamyl-L-asparagyl-L-seryl-L-alanyl-L-lysyl-L-phenylalanyl-L-prolyl-L-isoleucinamide; NEI (rat). Grades: ≥95%. CAS No. 125934-45-4. Molecular formula: C63H98N16O23. Mole weight: 1447.55.
Neuropeptide EI, rat acetate
Neuropeptide EI, rat acetate exhibits functional melanin-concentrating hormone (MCH) antagonist and melanocyte-stimulating hormone (MSH) agonist activities under different behavioral patterns. Synonyms: H-Glu-Ile-Gly-Asp-Glu-Glu-Asn-Ser-Ala-Lys-Phe-Pro-Ile-NH2.CH3CO2H; L-α-Glutamyl-L-isoleucylglycyl-L-α-aspartyl-L-α-glutamyl-L-α-glutamyl-L-asparaginyl-L-seryl-L-alanyl-L-lysyl-L-phenylalanyl-L-prolyl-L-isoleucinamide acetate; Pro-MCH (AA 131-143) acetate; Pro-MCH [131-143] acetate. Grades: ≥95%. Molecular formula: C65H102N16O25. Mole weight: 1507.60.
Neuropeptide FF
Neuropeptide FF (NPFF), an octapeptide belonging to the RF-amide family of peptides, interacts with two distinct G-protein-coupled receptors, NPFF(1) and NPFF(2) and has wide variety of physiological functions in the brain including central cardiovascular and neuroendocrine regulation [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: NPFF. CAS No. 99566-27-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1248.
Neuropeptide FF
Neuropeptide FF, which belongs to the RF-amide family of peptides, is an endogenous antiopioid peptide and agonist at NPFF1 and NPFF2 receptors (Ki= 2.82 and 0.21 nM respectively). Neuropeptide FF has anti-opioid effects in rodent models, inhibiting morphine-induced analgesia and inducing abstinence in morphine-tolerant rats. It also inhibits acquisition of conditioned place preference to cocaine in rats when administered at doses of 10 and 20 nmol. Uses: Narcotic antagonists. Synonyms: NPFF; H-Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe-NH2; L-phenylalanyl-L-leucyl-L-phenylalanyl-L-glutaminyl-L-prolyl-L-glutaminyl-L-arginyl-L-phenylalaninamide. Grades: ≥95% by HPLC. CAS No. 99566-27-5. Molecular formula: C54H76N14O10. Mole weight: 1081.27.
Neuropeptide K (human, porcine, rat)
Neuropeptide K (human, porcine, rat), a brain tachykinin, is a major tachykinin in plasma and tumor tissues of carcinoid patients. Synonyms: Neuropeptide K, porcine; H-Asp-Ala-Asp-Ser-Ser-Ile-Glu-Lys-Gln-Val-Ala-Leu-Leu-Lys-Ala-Leu-Tyr-Gly-His-Gly-Gln-Ile-Ser-His-Lys-Arg-His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met-NH2; Neuropeptide K (swine); L-alpha-aspartyl-L-alanyl-L-alpha-aspartyl-L-seryl-L-seryl-L-isoleucyl-L-alpha-glutamyl-L-lysyl-L-glutaminyl-L-valyl-L-alanyl-L-leucyl-L-leucyl-L-lysyl-L-alanyl-L-leucyl-L-tyrosyl-glycyl-L-histidyl-glycyl-L-glutaminyl-L-isoleucyl-L-seryl-L-histidyl-L-lysyl-L-arginyl-L-histidyl-L-lysyl-L-threonyl-L-alpha-aspartyl-L-seryl-L-phenylalanyl-L-valyl-glycyl-L-leucyl-L-methioninamide; NPK (human, porcine, rat). Grades: ≥95%. CAS No. 96827-05-3. Molecular formula: C175H284N52O52S. Mole weight: 3980.57.
Neuropeptide SF (human)
Neuropeptide SF human augments paraventricular corticotrophin-releasing hormone (CRH) release and increases adrenocorticotropic hormone (ACTH) and corticosterone levels in the plasma. Neuropeptide SF human play a physiologic role in the regulation of such circadian functions as the activity of motor centers and the HPA axis, through the release of CRH [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Neuropeptide NPFF (human). CAS No. 192387-39-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1245.
Neuropeptide SF (mouse, rat)
Neuropeptide SF (mouse, rat) is a neuropeptide FF receptor agonist (Ki= 48.4 and 12.1 nM for NPFF1 and NPFF2, respectively). NPSF may play a physiologic role in the regulation of such circadian functions as the activity of motor centers and the HPA axis, through the release of CRH. Synonyms: Ser-Leu-Ala-Ala-Pro-Gln-Arg-Phe-NH2. CAS No. 230960-31-3. Molecular formula: C40H65N13O10. Mole weight: 888.03.
Neuropeptide SF (mouse, rat) acetate
Neuropeptide SF (mouse, rat) acetate is a neuropeptide FF receptor agonist (Ki = 48.4 and 12.1 nM for NPFF1 and NPFF2, respectively). NPSF may play a physiologic role in the regulation of such circadian functions as the activity of motor centers and the HPA axis, through the release of CRH. Synonyms: H-Ser-Leu-Ala-Ala-Pro-Gln-Arg-Phe-NH2.CH3CO2H; L-seryl-L-leucyl-L-alanyl-L-alanyl-L-prolyl-L-glutaminyl-L-arginyl-L-phenylalaninamide acetic acid. Grades: ≥95%. CAS No. 2760881-61-4. Molecular formula: C42H69N13O12. Mole weight: 948.08.
Neuropeptide S (human), one of the "youngest" members among the biologically active peptides, is a potent endogenous neuropeptide S receptor agonist (EC50 = 9.4 nM), which modulates arousal, wakefulness, anxiety, fear-extinction, and fear memory consolidation. Synonyms: NPS (human); H-Ser-Phe-Arg-Asn-Gly-Val-Gly-Thr-Gly-Met-Lys-Lys-Thr-Ser-Phe-Gln-Arg-Ala-Lys-Ser-OH; L-seryl-L-phenylalanyl-L-arginyl-L-asparagyl-glycyl-L-valyl-glycyl-L-threonyl-glycyl-L-methionyl-L-lysyl-L-lysyl-L-threonyl-L-seryl-L-phenylalanyl-L-glutaminyl-L-arginyl-L-alanyl-L-lysyl-L-serine. Grades: ≥95%. CAS No. 412938-67-1. Molecular formula: C93H155N31O28S. Mole weight: 2187.48.
Neuropeptide S (human)
Neuropeptide S human, a neuropeptide, is a potent cognate neuropeptide S receptor (NPSR) agonist. Neuropeptide S human can be used for Alzheimer's disease (AD) research[1]. Uses: Scientific research. Group: Peptides. CAS No. 412938-67-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1389.
Neuropeptide S (mouse) is a bioactive peptide. Neuropeptide S (mouse), as a neurotransmitter/neuromodulator of 20 amino acids, can be used for the research of arousal, anxiety, locomotion, feeding behaviors, memory and agent addiction [1]. Uses: Scientific research. Group: Peptides. CAS No. 412938-74-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1437.
Neuropeptide S (Mouse)
Neuropeptide S, a 20 amino acid modulatory neuropeptide, is a potent endogenous neuropeptide S receptor (NPSR) agonist (EC50 = 3 nM). Previous studies in rat and mouse showed that NPS is expressed by a few well-defined pontine neuronal clusters that project to several distinct rostral forebrain areas, including the septum, hypothalamus and thalamus. Its G-protein-coupled receptor, NPSR1, is however widely distributed throughout the brain and mediates predominantly excitatory signals. In agreement, the NPS neurons are glutamatergic. Synonyms: H-Ser-Phe-Arg-Asn-Gly-Val-Gly-Ser-Gly-Ala-Lys-Lys-Thr-Ser-Phe-Arg-Arg-Ala-Lys-Gln-OH. CAS No. 412938-74-0. Molecular formula: C93H156N34O27. Mole weight: 2182.47.
Neuropeptide S (Mouse) acetate
Neuropeptide S (Mouse) acetate, a 20 amino acid modulatory neuropeptide, is a potent endogenous neuropeptide S receptor (NPSR) agonist (EC50 = 3 nM). It can be used for the research of arousal, anxiety, locomotion, feeding behaviors, memory, and drug addiction. Synonyms: 1-20-Protein (mouse TGR23-2 ligand) acetate; L-Seryl-L-phenylalanyl-L-arginyl-L-asparaginylglycyl-L-valylglycyl-L-serylglycyl-L-alanyl-L-lysyl-L-lysyl-L-threonyl-L-seryl-L-phenylalanyl-L-arginyl-L-arginyl-L-alanyl-L-lysyl-L-glutamine acetate; H-Ser-Phe-Arg-Asn-Gly-Val-Gly-Ser-Gly-Ala-Lys-Lys-Thr-Ser-Phe-Arg-Arg-Ala-Lys-Gln-OH.CH3CO2H. Grades: ≥95%. Molecular formula: C95H160N34O29. Mole weight: 2242.53.
Neuropeptide S (Rat)
Neuropeptide S, a neuropeptide that plays a major role in regulating sleep and stress, is a potent endogenous neuropeptide S receptor (NSPR) agonist (EC50 = 3.2 nM for inducing intracellular calcium mobilization in HEK293 cells expressing the human receptor). It enhances memory during the consolidation phase and interacts with noradrenergic systems in the brain. Synonyms: NPS (rat); H-Ser-Phe-Arg-Asn-Gly-Val-Gly-Ser-Gly-Val-Lys-Lys-Thr-Ser-Phe-Arg-Arg-Ala-Lys-Gln-OH; L-seryl-L-phenylalanyl-L-arginyl-L-asparaginylglycyl-L-valylglycyl-L-serylglycyl-L-valyl-L-lysyl-L-lysyl-L-threonyl-L-seryl-L-phenylalanyl-L-arginyl-L-arginyl-L-alanyl-L-lysyl-L-glutamine. Grades: ≥95%. CAS No. 412938-75-1. Molecular formula: C95H160N34O27. Mole weight: 2210.52.
Neuropeptide W-23 (human)
Neuropeptide W-23 (human) (NPW-23), the active form of Neuropeptide W, is an endogenous agonist of NPBW1 (GPR7) and NPBW2 (GPR8) [1]. Uses: Scientific research. Group: Peptides. Alternative Names: NPW-23. CAS No. 383415-79-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1035.
Neuropeptide W-23 (human)
Neuropeptide W-23 (human), the active form of Neuropeptide W, is an endogenous peptide agonist of Neuropeptide B/Neuropeptide W receptors NPBW1 and NPBW2 (previously known as GPR7 and GPR8 respectively). It dose-dependently inhibited cAMP accumulation induced by forskolin in CHO-GPR7 and CHO-GPR8 cells, with IC50 values of 0.025 and 0.178 nM, respectively. Synonyms: NPW-23; H-Trp-Tyr-Lys-His-Val-Ala-Ser-Pro-Arg-Tyr-His-Thr-Val-Gly-Arg-Ala-Ala-Gly-Leu-Leu-Met-Gly-Leu-OH; L-tryptophyl-L-tyrosyl-L-lysyl-L-histidyl-L-valyl-L-alanyl-L-seryl-L-prolyl-L-arginyl-L-tyrosyl-L-histidyl-L-threonyl-L-valyl-glycyl-L-arginyl-L-alanyl-L-alanyl-glycyl-L-leucyl-L-leucyl-L-methionyl-glycyl-L-leucine. Grades: ≥95% by HPLC. CAS No. 383415-79-0. Molecular formula: C119H183N35O28S. Mole weight: 2584.01.
Neuropeptide w-30(rat)
Neuropeptide w-30(rat). Uses: Designed for use in research and industrial production. Additional or Alternative Names: H-TRP-TYR-LYS-HIS-VAL-ALA-SER-PRO-ARG-TYR-HIS-THR-VAL-GLY-ARG-ALA-SER-GLY-LEU-LEU-MET-GLY-LEU-ARG-ARG-SER-PRO-TYR-LEU-TRP-OH;RPPL8 (42-71);RL8C;NPW30 (RAT);NEUROPEPTIDE W-30 (RAT);PREPROPROTEIN L8 (42-71) (RAT);TRP-TYR-LYS-HIS-VAL-ALA-SER-PRO-ARG-TYR-HIS. Product Category: Heterocyclic Organic Compound. CAS No. 383415-90-5. Molecular formula: C165H249N49O38S. Mole weight: 3559.11. Purity: 0.96. Product ID: ACM383415905. Alfa Chemistry ISO 9001:2015 Certified.
Neuropeptide Y (13-36), amide, human
Neuropeptide Y (13-36), amide, human is a selective neuropeptide Y2 receptor agonist. Synonyms: Neuropeptide Y (13-36), human; Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2; Neuropeptide Y (13-36) (human, rat); L-prolyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-methionyl-L-alanyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-seryl-L-alanyl-L-leucyl-L-arginyl-L-histidyl-L-tyrosyl-L-isoleucyl-L-asparagyl-L-leucyl-L-isoleucyl-L-threonyl-L-arginyl-L-glutaminyl-L-arginyl-L-tyrosinamide. Grades: 95%. CAS No. 122341-40-6. Molecular formula: C134H207N41O36S. Mole weight: 3000.39.
Neuropeptide Y (13-36), porcine
Neuropeptide Y (13-36), porcine is a selective neuropeptide Y 2 receptor agonist [1]. Uses: Scientific research. Group: Peptides. Alternative Names: NPY 13-36. CAS No. 113662-54-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1011.
Neuropeptide Y 13-36 (porcine)
Neuropeptide Y 13-36 (porcine) is a selective neuropeptide Y2 receptor agonist (Ki = 0.18 nM). It mimics the effects of NPY at presynaptic receptors in vas deferens. Synonyms: H-Pro-Ala-Glu-Asp-Leu-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2. CAS No. 113662-54-7. Molecular formula: C135H209N41O36. Mole weight: 2982.36.
Neuropeptide Y 22-36
Neuropeptide Y(22-36) is a fragment of neuropeptide Y containing 15 amino acids. Synonyms: Neuropeptide Y (22-36) pig; Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2; L-Seryl-L-alanyl-L-leucyl-L-arginyl-L-histidyl-L-tyrosyl-L-isoleucyl-L-asparaginyl-L-leucyl-L-isoleucyl-L-threonyl-L-arginyl-L-glutaminyl-L-arginyl-L-tyrosinamide; NPY 22-36, porcine. Grades: 95%. CAS No. 119019-65-7. Molecular formula: C85H139N29O21. Mole weight: 1903.19.
Neuropeptide y(2-36)(human,rat)
Neuropeptide y(2-36)(human,rat). Uses: Designed for use in research and industrial production. Additional or Alternative Names: H-PRO-SER-LYS-PRO-ASP-ASN-PRO-GLY-GLU-ASP-ALA-PRO-ALA-GLU-ASP-MET-ALA-ARG-TYR-TYR-SER-ALA-LEU-ARG-HIS-TYR-ILE-ASN-LEU-ILE-THR-ARG-GLN-ARG-TYR-NH2;PRO-SER-LYS-PRO-ASP-ASN-PRO-GLY-GLU-ASP-ALA-PRO-ALA-GLU-ASP-MET-ALA-ARG-TYR-TYR-SER-ALA-LEU-ARG-HIS-TYR-ILE-. Product Category: Heterocyclic Organic Compound. CAS No. 123139-39-9. Molecular formula: C180H276N54O55S. Product ID: ACM123139399. Alfa Chemistry ISO 9001:2015 Certified.
Neuropeptide Y (29-64)
Neuropeptide Y is a 36 amino-acid neuropeptide that is involved in various physiological and homeostatic processes in both the central and peripheral nervous systems. Synonyms: Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr; L-tyrosyl-L-prolyl-L-seryl-L-lysyl-L-prolyl-L-alpha-aspartyl-L-asparagyl-L-prolyl-glycyl-L-alpha-glutamyl-L-alpha-aspartyl-L-alanyl-L-prolyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-methionyl-L-alanyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-seryl-L-alanyl-L-leucyl-L-arginyl-L-histidyl-L-tyrosyl-L-isoleucyl-L-asparagyl-L-leucyl-L-isoleucyl-L-threonyl-L-arginyl-L-glutaminyl-L-arginyl-L-tyrosine. Grades: ≥95%. CAS No. 303052-45-1. Molecular formula: C189H284N54O58S. Mole weight: 4272.66.
Neuropeptide Y(29-64)
Neuropeptide Y(29-64) is a 36 amino acid peptide, a fragment of Neuropeptide Y. Uses: Scientific research. Group: Peptides. CAS No. 303052-45-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1601.
Neuropeptide Y (3-36) (human, rat)
Neuropeptide Y (3-36) (human, rat) is a neuropeptide Y (NPY) metabolite formed by dipeptidyl peptidase-4 (DPP4) and is a selective Y2/Y5 receptor agonist. It is a major degradation product of NPY in serum, and reduces norepinephrine release through the Y2 receptor. Synonyms: Neuropeptide Y Fragment 3-36 human, rat; H-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2; NPY 3-36 human, rat; L-seryl-L-lysyl-L-prolyl-L-alpha-aspartyl-L-asparagyl-L-prolyl-glycyl-L-alpha-glutamyl-L-alpha-aspartyl-L-alanyl-L-prolyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-methionyl-L-alanyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-seryl-L-alanyl-L-leucyl-L-arginyl-L-histidyl-L-tyrosyl-L-isoleucyl-L-asparagyl-L-leucyl-L-isoleucyl-L-threonyl-L-arginyl-L-glutaminyl-L-arginyl-L-tyrosinamide. Grades: ≥95%. CAS No. 150138-78-6. Molecular formula: C175H269N53O54S. Mole weight: 4011.45.
Neuropeptide Y (free acid) (human, rat)
Neuropeptide Y is a 36 amino-acid neuropeptide that is involved in various physiological and homeostatic processes in both the central and peripheral nervous systems. Synonyms: H-Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2; NPY (free acid) (human, rat); Neuropeptide Y, human, rat. Grades: ≥95%. CAS No. 99575-89-0. Molecular formula: C189H285N55O57S. Mole weight: 4271.74.
Neuropeptide Y, Human - CAS 90880-35-6
A potent vasoconstrictor. Group: Fluorescence/luminescence spectroscopy.
Neuropeptide Y (human, rat)
Neuropeptide Y (human, rat) is a widely distributed endogenous neuropeptide involved in the control of food intake, sexual behavior and blood pressure. NPY has also been shown to interact with the immune system, promoting gastrointestinal inflammation, as well as exhibiting an antimicrobial effect against several gut bacteria. Synonyms: NPY (human, rat). CAS No. 90880-35-6. Molecular formula: C189H285N55O57S. Mole weight: 4271.7.
Neuropeptide Y (human,rat,mouse)
Neuropeptide Y (human,rat,mouse) is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity. Uses: Scientific research. Group: Peptides. Alternative Names: Neuropeptide Y (29-64), amide. CAS No. 90880-35-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0198.
Neuropeptide Y (porcine) is a widely distributed endogenous neuropeptide involved in regulation of circadian rhythms, sexual functioning, anxiety and stress response, and regulation of food intake (Ki= 0.17, 0.04 nM at human and Y2 respectively). It inhibits cholecystokinin- and secretin-stimulated pancreatic secretion. Synonyms: H-Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Leu-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2. CAS No. 83589-17-7. Molecular formula: C190H287N55O57. Mole weight: 4254.
Neuropeptide Y (scrambled)
Neuropeptide Y (scrambled) is the control peptide for neuropeptide Y (NPY). Neuropeptide Y is a widely distributed endogenous neuropeptide involved in the control of food intake, sexual behavior and blood pressure. Synonyms: SKPQRDANREPTRYAIYDYSNPDIELHYLRPAYALG-NH2. Molecular formula: C190H287N55O57. Mole weight: 4253.7.
Neuropeptidey(swine),31-L-Leucine-34-l-proline-
Neuropeptidey(swine),31-L-Leucine-34-l-proline-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: [LEU31,PRO34] NEUROPEPTIDE Y (1-36), PORCINE;[LEU31, PRO34]-NEUROPEPTIDE Y, HUMAN, PORCINE;(LEU31,PRO34)-NEUROPEPTIDE Y (PORCINE);[LEU31, PRO34]-NEUROPEPTIDE Y (PORCINE) (BOVINE);(LEU31,PRO34)-NPY (PORCINE);[LEU31, PRO34]-NPY (PORCINE) (BOVINE);ANTI-NSEC. Product Category: Heterocyclic Organic Compound. CAS No. 125580-28-1. Molecular formula: C190H286N54O56. Mole weight: 4222.63. Purity: 0.96. Canonical SMILES: CCC(C)C(C(=O)NC(CC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(C(C)O)C(=O)NC(CCCNC(=N)N)C(=O)N1CCCC1C(=O)NC(CCCNC(=N)N)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)N)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)C(CC4=CNC=N4)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC5=CC=C(C=C5)O)NC(=O)C(CC6=CC=C(C=C6)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C7CCCN7C(=O)C(C)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)CNC(=O)C8CCCN8C(=O)C(CC(=O)N)NC(=O)C(CC(=O)O)NC(=O)C9CCCN9C(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C1CCCN1C(=O)C(CC1=CC=C(C=C1)O)N. Product ID: ACM125580281. Alfa Chemistry ISO 9001:2015 Certified.
Neuropoietin from mouse
recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
A brain-permeable ester of pyruvate and salicylic acid that exhibits anti-oxidative and anti-excitotoxic properties. Following its uptake by the brain tissue, it releases pyruvate and salicylic acid via ester hydrolysis (t1/2 of 43 min in serum). Exerts strong neuroprotective effects in the post-ischemic brain and significantly reduces infarct volume (27% and 65% reduction in 6 and 12 hours following i.v. administration of 10mg/kg in a rat model). Also, blocks Zn2+-induced neuronal cell death. Its neuroprotective effects are attributed to its ability to prevent NAD- and ATP-depletion in post-ischemic brain and suppression of NF-kB activity by reducing IkB-a degradation. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Neuroprotectin A
Neuroprotectin A is a cyclopeptide produced by the strain of Streptomyces sp. Q27107. It has the function of protecting chicken brain neuron culture from excitatory toxicity induced by glutamate and red alginate. Synonyms: Complestatin A. Molecular formula: C61H45Cl6N7O16. Mole weight: 1344.76.
Neuroprotectin B
Neuroprotectin B is a cyclopeptide produced by the strain of Streptomyces sp. Q27107. It has the function of protecting chicken brain neuron culture from excitatory toxicity induced by glutamate and red alginate. Synonyms: Complestatin B. Molecular formula: C61H45Cl6N7O17. Mole weight: 1360.76.
Neurotensin is a selective, non-competitive NMDA receptor antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 39379-15-2. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C78H121N21O20, Molecular Weight: 1672.94. US Biological Life Sciences.
Worldwide
Neurotensin
Neurotensin, a gut tridecapeptide, acts as a potent cellular mitogen for various colorectal and pancreatic cancers which possess high-affinity neurotensin receptors ( NTR ). Uses: Scientific research. Group: Peptides. CAS No. 39379-15-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0234.
Neurotensin
Neurotensin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NEUROTENSIN, BOVINE;NEUROTENSIN (HUMAN, BOVINE, CANINE);NEUROTENSIN (HUMAN, BOVINE, CANINE) 2ACOH 6H2O;NEUROTENSIN (1-13);NEUROTENSIN;PYR-LYENKPRRPYIL;PYR-LEU-TYR-GLU-ASN-LYS-PRO-ARG-ARG-PRO-TYR-ILE-LEU;PYR-LEU-TYR-GLU-ASN-LYS-PRO-ARG-ARG-PRO-TYR-ILE-LEU. Product Category: Heterocyclic Organic Compound. CAS No. 39379-15-2. Molecular formula: C78H121N21O20. Mole weight: 1672.92. Purity: 0.96. IUPACName: 2-[[2-[[2-[[1-[2-[[2-[[1-[6-amino-2-[[4-amino-2-[[4-carboxy-2-[[3-(4-hydroxyphenyl)-2-[[4-methyl-2-[(5-oxopyrrolidine-2-carbonyl)amino]pentanoyl]amino]propanoyl]amino]butanoyl]amino]-4-oxobutanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomet. Density: 1.46g/cm³. Product ID: ACM39379152. Alfa Chemistry ISO 9001:2015 Certified.