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| Product | Description | |
|---|---|---|
| NRP1 antagonist 1 | NRP1 antagonist 1 (compound 12a) is a potent NRP1 antagonist with an IC 50 of 19.1 μM. NRP1 antagonist 1 has the potential for cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2569598-01-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133034. |  |
| NRPE | NRPE. Group: Biochemicals. Alternative Names: (all-E)-1,2-di-2-palmitin. Grades: Highly Purified. CAS No. 30576-47-7. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C57H100NO8P. US Biological Life Sciences. |  Worldwide |
| N-[(RS)-1-Carboxy-3-phenyl-propyl]-Ala-Ala-Phe-4-Abz-OH | N-[(RS)-1-Carboxy-3-phenyl-propyl]-Ala-Ala-Phe-4-Abz-OH is a specific inhibitor of thimet oligopeptidase (soluble metalloendopeptidase, EC 3.4.24.15) with a Ki of 0.027±0.003 μM. Neprilysin (Endopeptidase-2, EC 3.4.24.11) converts it into a potent inhibitor of angiotensin-converting enzyme (ACE). Synonyms: Cpp-AAF-pAb; Cfp-aaf-pab; N-(1-Carboxy-3-phenylpropyl)-ala-ala-phe-p-aminobenzoate; N-(1-Carboxy-3-phenylpropyl)-alanyl-alanyl-phenylalanine-4-aminobenzoate; L-Phenylalaninamide, N-(1-carboxy-3-phenylpropyl)-L-alanyl-L-alanyl-N-(4-carboxyphenyl)-; N-(1-Carboxy-3-phenylpropyl)-L-alanyl-N-{(2S)-2-[(4-carboxyphenyl)amino]-3-phenylpropanoyl}-L-alaninamide. Grades: ≥95%. CAS No. 116560-97-5. Molecular formula: C32H36N4O7. Mole weight: 588.66. |  |
| N-((R,S)-2-Carboxy-3-phenylpropionyl)-L-leucine | Heterocyclic Organic Compound. Alternative Names: N-([R,S]-2-CARBOXY-3-PHENYLPROPIONYL)-L-LEUCINE, 102601-55-8. CAS No. 102601-55-8. Molecular formula: C16H21NO5. Mole weight: 307.3. Purity: 0.96. IUPACName: 2-[(1-hydroxy-4-methyl-1-oxopentan-2-yl)amino]-6-propanoylbenzoic acid. Canonical SMILES: CCC (=O)C1=C (C (=CC=C1)NC (CC (C)C)C (=O)O)C (=O)O. Catalog: ACM102601558. |  |
| N-((RS)-2-Hydroxy-propyl)-Val-Leu-anilide | Synonyms: N-((RS)-2-Hydroxy-propyl)-VL-anilide; L-Leucinamide, N-(2-hydroxypropyl)-L-valyl-N-phenyl- (9CI). CAS No. 282726-24-3. Molecular formula: C20H33N3O3. Mole weight: 363.49. | |
| N-rt-Butyloxycarbonyl Gabapentin | Protected Gabapentin. Amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant. Group: Biochemicals. Alternative Names: 1-[[[ (1, 1-Dimethylethoxy) carbonyl]amino]methyl]-cyclohexaneacetic Acid; 2- [1- [ (tert-Butoxycarbonylamino) methyl] cyclohexyl] acetic Acid; [1- (tert-Butoxycarbonylamino methyl ) cyclohexyl] acetic Acid. Grades: Highly Purified. CAS No. 227626-60-0. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| NRTN (Neurturin), Human | It is a cell-penetrating peptide (CPP) derived from human neurturin protein. NRTN can permeate cell membrane at low micromolar concentration and has no obvious effect on cell membrane. NRTN has high activity as a siRNA transfection reagent. Synonyms: H-Gly-Ala-Ala-Glu-Ala-Ala-Ala-Arg-Val-Tyr-Asp-Leu-Gly-Leu-Arg-Arg-Leu-Arg-Gln-Arg-Arg-Arg-Leu-Arg-Arg-Glu-Arg-Val-Arg-Ala-OH. Grades: >98%. Molecular formula: C150H268N64O39. Mole weight: 3592.20. | |
| Nru I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA (dam-) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme about 50% of the dna fragments can be ligated and 90% of them can be recut. in the presence of 10% peg ligation is better. Group: Restriction Enzymes. Purity: 500 U; 2500U. TCG↑CGA AGC↓GCT. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer W. Storage: -20°C. Form: Liquid. Source: Nocardia rubra. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 50% glycerol. Cat No: ET-1142RE. |  |
| NRWC | NRWC is an antimicrobial peptide found in Bacillus subtilis, and has antibacterial activity. Synonyms: Asn-Arg-Trp-Cys-Phe-Ala-Gly-Asp-Asp; NRWC (Bacteriocin). Grades: >98%. Molecular formula: C46H62N14O15S. Mole weight: 1083.14. | |
| NRX-204647 | NRX-204647 is a Retinoic acid receptor gamma-selective inverse agonist. Synonyms: NRX204647; NRX-204647; NRX 204647. 4-((1E,3Z)-3-(hydroxyimino)-3-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-en-1-yl)benzoic acid. Grades: 98%. CAS No. 1351452-80-6. Molecular formula: C24H27NO3. Mole weight: 377.78. | |
| NRX-4204 | NRX-4204, also known as NRX-194204 and AGN-194204, is an orally bioavailable synthetic retinoid X receptor (RXR) agonist with potential antineoplastic and anti-inflammatory activities. Rexinoid NRX 194204 selectively binds to and activates RXRs. Because RXRs can form heterodimers with several nuclear receptors (NRs), RXR activation by this agent may result in a broad range of gene expression depending on the effector DNA response elements activated. Rexinoid NRX 194204 may inhibit the tumor-necrosis factor (TNF)-mediated release of nitric oxide (NO) and interleukin 6 (IL6) and may inhibit tumor cell proliferation. This agent appears to be less toxic than RAR-selective ligands. Synonyms: IRX4204; IRX-4204; IRX 4204; NRX4204; NRX-4204; NRX 4204; NRX194204; NRX 194204; NRX-194204; AGN194204; AGN 194204; AGN-194204; VTP 194204; VTP194204; VTP-194204. CAS No. 220619-73-8. Molecular formula: C24H32O2. Mole weight: 352.51. | |
| NS | NS is a mixture of polysaccharides produced by Streptomyces flavochromogenes 280, consisting of NS1~NS17. It has inhibitory effect against α-amylase and glucoamylase. | |
| NS-018 | NS-018, a selective JAK2 as well as Src family tyrosine kinases inhibitor that could probably induce the apoptosis of tumor cells. It is still under Phase I/II trial against Myelofibrosis. IC50: 470 nM for Ba/F3-JAK2V617F cell. Uses: Ns-018 is a selective jak2 as well as src family tyrosine kinases inhibitor that could probably induce the apoptosis of tumor cells. Synonyms: NS-018; NS 018; NS018; UNII-56R994WX4L; 56R994WX4L; GTPL7839; GTPL 7839; GTPL-7839; SCHEMBL14954406; UQTPDWDAYHAZNT-AWEZNQCLSA-N. Grades: 98%. CAS No. 1239358-86-1. Molecular formula: C21H20FN7. Mole weight: 389.43. | |
| NS-018 hydrochloride | The hydrochloride salt form of NS-018 which is a selective JAK2 as well as Src family tyrosine kinases inhibitor that could probably induce the apoptosis of tumor cells. It is still under Phase I/II trial against Myelofibrosis. IC50: 470 nM for Ba/F3-JAK2. Uses: The hydrochloride salt form of ns-018 which is a selective jak2 as well as src family tyrosine kinases inhibitor that could probably induce the apoptosis of tumor cells. Synonyms: NS018 hydrochloride; NS 018 hydrochloride. Grades: 98%. CAS No. 1239358-85-0. Molecular formula: C21H21ClFN7. Mole weight: 425.89. | |
| NS 11021 | NS 11021. Group: Biochemicals. Grades: Purified. CAS No. 956014-19-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NS 11021 | NS 11021 is a potent and specific Ca 2+ -activated big-conductance K + Channels (KCa1.1 channels) activator. NS 11021 at concentrations above 0.3 μM activates KCa1.1 in a concentration-dependent manner by parallelshifting the channel activation curves to more negative potentials [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 956014-19-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13103. | |
| NS 11021 | NS 11021 is an activator of large-conductance Ca2+-activated potassium channels. It has been shown to relax intracavernous arterial rings and corpus cavernosum strips in vitro. Synonyms: NS-11021; NS 11021; NS11021. N'-[3,5-Bis(trifluoromethyl)phenyl]-N-[4-bromo-2-(2H-tetrazol-5-yl-phenyl]thiourea. Grades: ≥98% by HPLC. CAS No. 956014-19-0. Molecular formula: C16H9BrF6N6S. Mole weight: 511.24. | |
| NS-11021 | NS-11021 is an activator of large-conductance Ca2+-activated potassium channels (BKCa, KCa1.1). BK channel activation by NS11021 decreases excitability and contractility of urinary bladder smooth muscle. NS11021 enhances erectile responses in rats. Group: Activators. Alternative Names: NS-11021; NS 11021; NS11021. CAS No. 956014-19-0. Molecular formula: C16H9BrF6N6S. Mole weight: 511.24. Appearance: Solid powder. Purity: >98%. IUPACName: N'-[3,5-bis(trifluoromethyl)phenyl]-N-[4-bromo-2-(2H-tetrazol-5-yl)phenyl]-thiourea. Canonical SMILES: S=C (NC1=CC (C (F) (F)F)=CC (C (F) (F)F)=C1)NC2=CC=C (Br)C=C2C3=NNN=N3. Catalog: ACM956014190. | |
| NS 11394 | NS 11394 is a drug with selectivity for the α3 and α5 subtypes. It acts as a subtype-selective positive allosteric modulator at GABAA receptors. It is used as an analgesic for use in chronic or neuropathic pain. It is unique in having superior efficacy at alpha(3) receptors and low efficacy at alpha(1) receptors in vitro. It has an excellent pharmacokinetic profile, which correlates with pharmacodynamic endpoints, yielding a high level of confidence in deriving in vivo conclusions anchored to an in vitro selectivity profile and allowing for translation to higher species. It impairs memory in both rats and mice because of its efficacy at GABA(A)-alpha(5) receptors. It is potent and highly effective in rodent anxiety models. It has a significantly reduced side effect profile in rat and mouse, even at full CNS receptor occupancy. Uses: Ns-11394 is used as an analgesic for use in chronic or neuropathic pain. Synonyms: NS-11394; NS 11394; NS11394; 2-[3-[5-(2-hydroxypropan-2-yl)benzimidazol-1-yl]phenyl]benzonitrile;NS-11394;3'-[5-(1-Hydroxy-1-methylethyl)-1H-benzimidazol-1-yl]-[1,1'-biphenyl]-2-carbonitrile. Grades: >98 %. CAS No. 951650-22-9. Molecular formula: C23H19N3O. Mole weight: 353.42. | |
| NS-1209 | NS-1209, an AMPA/GluR5 receptor antagonist, is a antiepileptic drug candidate currently under clinical trials. Synonyms: 2-[[5-[4-(dimethylsulfamoyl)phenyl]-8-methyl-2-oxo-7,9-dihydro-6H-pyrrolo[3,2-h]isoquinolin-3-yl]amino]oxy-4-hydroxybutanoic acid; NS-1209; NS 1209; NS1209; 245063-59-6; SPD-502; SPD502; SPD 502. Grades: >98%. CAS No. 245063-59-6. Molecular formula: C24H28N4O7S. Mole weight: 516.57. | |
| NS 1619 | NS 1619. Group: Biochemicals. Grades: Purified. CAS No. 153587-01-0. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| NS 1619 | NS 1619, a benzimidazalone derivative, activates BKca channels in a number of tissues. However, the effect of NS 1619 was dependent upon the presence of Ca 2+ ions at the intracellular surface, for at free Ca2+ ion concentrations of 0.1/zM and below (a ra. Synonyms: 3-[2-hydroxy-5-(trifluoromethyl)phenyl]-6-(trifluoromethyl)-1H-benzimidazol-2-oneNS 1619; NS1619153587-01-0NS-16191-(2-hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzo[d]imidazol-2(3H)-oneCHEMBL384903. Grades: >98 %. CAS No. 153587-01-0. Molecular formula: C15H8F6N2O2. Mole weight: 362.23. | |
| NS-1619 | NS-1619 is an opener of large conductance Ca 2+ -activated K + (BK) channel. NS-1619 is a highly effective relaxant with an EC 50 of about 10 - 30 μM in several smooth muscles of blood vessels and other tissues [1]. NS1619 inhibits proliferation and induces apoptosis in A2780 ovarian cancer cells [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 153587-01-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-12496. | |
| NS1643 | NS1643 is a partial agonist of human ether-a-go-go-related gene ( hERG ) K + channels with an EC 50 of 10.5 μM. NS1643 inhibits the growth of breast cancer tumors in TNBC mouse models. NS1643 inhibits cell migration and invasion of breast cancer cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 448895-37-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16916. | |
| NS 1643 | NS 1643. Group: Biochemicals. Alternative Names: 1, 3-Bis (2-hydroxy-5-trifluoromethylphenyl) urea; N, N'-bis[2-hydroxy-5- (trifluoromethyl) phenyl]urea. Grades: Highly Purified. CAS No. 448895-37-2. Pack Sizes: 10mg. Molecular Formula: C15H10F6N2O2S, Molecular Weight: 396.31. US Biological Life Sciences. | Worldwide |
| NS 1643 | NS 1643 is human ether-a-go-go related gene (hERG) KV11.1 channel activator (EC50 = 10.5 μM). Uses: Kv11.1 channel activator. Synonyms: NS-1643; NS 1643; NS1643. 1,3-Bis(2-hydroxy-5-trifluoromethylphenyl)urea;N,N'-Bis[2-hydroxy-5-(trifluoromethyl)phenyl]urea. Grades: ≥98 %. CAS No. 448895-37-2. Molecular formula: C15H10F6N2O3. Mole weight: 380.06. | |
| NS 1738 | NS 1738. Group: Biochemicals. Grades: Purified. CAS No. 501684-93-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NS 1738 | NS 1738 is an allosteric modulator of the α7-containing neuronal nicotinic acetylcholine receptors (nAChRs). It shows cognitive-enhancing properties in vivo. Synonyms: NS1738; NS 1738; NS-1738; N-(5-Chloro-2-hydroxyphenyl)-N'-[2-chloro-5-(trifluoromethyl)phenyl]urea. Grades: ≥99% by HPLC. CAS No. 501684-93-1. Molecular formula: C14H9Cl2F3N2O2. Mole weight: 365.13. | |
| NS1738 (1- (5-chloro-2-hydroxyphenyl) -3- (2-chloro-5- (trifluoromethyl) phenyl) urea, a7 nAChR Positive Allosteric Modulator, NS1738, NS 1738, NS-1738) | A biarylurea derivative that acts as a selective positive allosteric modulator selective for alpha7 nicotinic acetylcholine receptors (alpha7 nAChR) without substantial activity for alpha4beta2, alpha3beta3 and alpha1-containing receptors. Exhibits cognitive enhancing effects in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 501684-93-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| NS 19504 | NS 19504. Group: Biochemicals. Grades: Purified. CAS No. 327062-46-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NS 19504 | NS 19504 is an activator of large-conductance Ca2+-activated potassium channels. It has relaxing effects on bladder smooth muscle. Synonyms: NS 19504; NS19504; NS-19504; 5-[(4-Bromophenyl)methyl]-2-thiazolamine. Grades: ≥99% by HPLC. CAS No. 327062-46-4. Molecular formula: C10H9BrN2S. Mole weight: 269.16. | |
| N-((S)-1-Benzylpyrrolidin-3-yl)acetamide | Heterocyclic Organic Compound. Alternative Names: (S)-(-)-1-BENZYL-3-ACETAMIDOPYRROLIDINE;(S)-1-BENZYL-3-ACETYLAMINO PYRROLIDINE;(S)-N-Benzyl-3-AcetylaminoPyrrolidine;(S)-(-)-1-BENZYL-3-ACETAMIDOPYRROLIDINE , EE 99%;(S)-(-)-1-BENZYL-3-ACETAMIDOPYRROLIDINE, 98%, EE 99%;N-((S)-1-Benzylpyrrolidin-3-yl)acet. CAS No. 114636-30-5. Molecular formula: C13H18N2O. Mole weight: 218.29. Appearance: white or cream-colored solid. Purity: 0.96. IUPACName: N-(1-benzylpyrrolidin-3-yl)acetamide. Canonical SMILES: CC(=O)NC1CCN(C1)CC2=CC=CC=C2. Density: 1.1g/cm³. Catalog: ACM114636305. | |
| N-[(S)-1-Carbethoxybutyl]-(S)-alanine | Perindopril intermediate. Group: Biochemicals. Alternative Names: (S)-N-(1-Carboxyethyl)-L-norvaline 1-Ethyl Ester; N-((S)-Ethoxycarbonyl-1-butyl)-(S)-alanine. Grades: Highly Purified. CAS No. 82834-12-6. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| N-[(S)-(-)-1-Phenylethyl]imidazole-1-carboxamide | N-[(S)-(-)-1-Phenylethyl]imidazole-1-carboxamide. Group: Biochemicals. Alternative Names: (S)-N-(1-Phenylethyl)-1H-imidazole-1-carboxamide. Grades: Highly Purified. CAS No. 151252-80-1. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C12H13N3O. US Biological Life Sciences. | Worldwide |
| NS 2028 | S-2028 is a soluble guanylyl cyclase inhibitor. It can inhibit purified bovine lung guanylyl cyclase with IC50 values of 30 and 200 nM for basal and NO-stimulated enzymes. Synonyms: NS 2028; NS-2028; NS2028; 8-Bromo-1H,4H-[1,2,4]oxadiazolo[3,4-c][1,4]benzoxazin-1-one. Grades: ≥98% by HPLC. CAS No. 204326-43-2. Molecular formula: C9H5BrN2O3. Mole weight: 269.05. | |
| NS 2028 | NS 2028. Group: Biochemicals. Grades: Purified. CAS No. 204326-43-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NS-2214 | NS-2214, an azabicyclo compound, has been found to be a dopamine uptake inhibitor that was once studied in the treatment of Parkinson's disease. Synonyms: Brasofensine sulfate; BMS 204756; BMS-204756; NS 2214; NS2214; NS-2214; (E)-1-[(1R,3S,4R,5R)-3-(3,4-dichlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octan-4-yl]-N-methoxymethanimine;sulfuric acid. Grades: 98%. CAS No. 171655-92-8. Molecular formula: C16H22Cl2N2O5S. Mole weight: 425.32. | |
| NS-2359 | NS-2359, a serotonin-norepinephrine-dopamine reuptake inhibitor, may be able to reduce cocaine withdrawal symptoms, reduce cocaine craving and reduce cocaine-induced euphoria. Synonyms: (1S,3S,4R,5R)-3-(3,4-dichlorophenyl)-4-(methoxymethyl)-8-methyl-8-azabicyclo[3.2.1]octane; GSK 372475; GSK-372475; GSK372475; NS 2359; NS2359; NS-2359. Grades: >98%. CAS No. 195875-68-4. Molecular formula: C16H21Cl2NO. Mole weight: 558.675. | |
| N- [S- (2-Pyridylthio) cysteaminyl] ethylenediamine-N, N, N', N'-tetraacetic Acid, Monoamide, Technical grade 90% | A useful ligand for incorporation of EDTA-metal complexes into proteins particularly for investigating orientation of DNA binding proteins. Group: Biochemicals. Grades: Purified. CAS No. 143541-95-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| N-[S-(2-Pyridylthioethyl)-t-boc-aminooxyacetamide | N-[S-(2-Pyridylthioethyl)-t-boc-aminooxyacetamide. Group: Biochemicals. Alternative Names: Boc-aoa-NH-(CH2)2-S-S-pyr. Grades: Highly Purified. CAS No. 887407-46-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C15H22N2O4S2. US Biological Life Sciences. | Worldwide |
| N-[S-(2-Pyridylthioethyl)-t-Boc-aminooxyacetamide (Boc-Aoa-NH-(CH2)2-S-S-Pyr) | A useful disulfide cleavable linking reagent. Group: Biochemicals. Alternative Names: Boc-Aoa-NH-(CH2)2-S-S-Pyr. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| NS-304 | NS-304 is a selective prostacyclin IP1 receptor agonist as prodrug of the active form of MRE-269 with a Ki value of 20 nM. Uses: Antihypertensive agents. Synonyms: Selexipag; NS304; NS 304; ACT-293987; ACT293987; ACT 293987; 2-[4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]butoxy]-N-(methylsulfonyl)acetamide. Grades: ≥95%. CAS No. 475086-01-2. Molecular formula: C26H32N4O4S. Mole weight: 496.6. | |
| NS 30678 hydrochloride | NS 30678 hydrochloride is a dopamine D2 receptor ligand with surmountable/competitive-like D2 antagonist properties (Ki = 9.7 nM, IC50 = 7 nM, in HEK-hD2L-Gαqi5 cells). Synonyms: NS 30678 hydrochloride; NS30678 hydrochloride; NS-30678 hydrochloride. Grades: 99%. CAS No. 1193707-19-5. Molecular formula: C12H16ClNO4S.HCl. Mole weight: 342.24. | |
| NS309 | NS309 is a small- and intermediate- conductance Ca2+-activated K+ channels of SK and IK types whereas exhibits no activity at BK channels. Synonyms: 6,7-dichloro-3-(hydroxyamino)indol-2-one 6,7-dichloro-1H-indole-2,3-dione 3-oxime NS 309 NS-309 NS309 cpd. Grades: >98 %. CAS No. 18711-16-5. Molecular formula: C8H4Cl2N2O2. Mole weight: 231.04. | |
| NS 309 | NS 309. Group: Biochemicals. Grades: Purified. CAS No. 18711-16-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NS 3623 | NS 3623 is a KV11.1 (hERG) and KV4.3 channel activator. It can activate the IKr and Ito currents and display antiarrhythmic activity. Synonyms: NS3623; NS 3623; NS-3623. N-[4-Bromo-2-(1H-tetrazol-5-yl-phenyl]-N'-[3-(trifluoromethyl)phenyl]-urea. Grades: ≥99% by HPLC. CAS No. 343630-41-1. Molecular formula: C15H10BrF3N6O. Mole weight: 427.18. | |
| NS 3623 | NS 3623. Group: Biochemicals. Alternative Names: 1-(3-Trifluoromethylphenyl)-3-[2-(1H-tetrazol-5-yl)-4-bromophenyl]urea; N-[4-Bromo-2- (2H-tetrazol-5-yl) phenyl]-N'-[3- (trifluoromethyl) phenyl]-urea. Grades: Highly Purified. CAS No. 343630-41-1. Pack Sizes: 10mg. Molecular Formula: C15H10BrF3N6O, Molecular Weight: 427.18. US Biological Life Sciences. | Worldwide |
| NS 3694 | NS 3694 is an apoptosis inhibitor that inhibits the formation of the apoptosome Apaf-1 via blocking the activation of the initiator caspase 9. It does not affect apoptosome-independent caspase activation or enzymatic activity of caspases. Synonyms: NS 3694; NS3694; NS-3694; Apoptosis Inhibitor II; 4-chloro-2-[[3- (trifluoromethyl) phenyl]carbamoylamino]benzoic acid. Grades: 99%. CAS No. 426834-38-0. Molecular formula: C15H10ClF3N2O3. Mole weight: 358.7. | |
| NS 3763 | NS 3763. Group: Biochemicals. Grades: Purified. CAS No. 70553-45-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NS 3763 | NS 3763 is a non-competitive kainate receptor antagonist of GLUK5 subunit-containing receptors (IC50 = 1.6 mM)) without disrupting GLU(K6) subtype (IC50 > 30 microM). Besides, NS 3763 has minimal activity at AMPA and NMDA receptors (IC50 > 30 μM). Synonyms: NS3763; NS 3763; NS-3763. 1,?3-Benzenedicarboxylic acid, 4,?6-bis(benzoylamino)?-; 4,6-Bis(benzoylamino)-1,3-benzenedicarboxylic acid; 4,6-Dibenzamidoisophthalic acid. CAS No. 70553-45-6. Molecular formula: C22H16N2O6. Mole weight: 404.37. | |
| NS383 | NS383 is a potent and uniquely selective inhibitor of rat ASICs containing 1a and/or 3 subunits. NS383 inhibits H(+)-activated currents recorded from rat homomeric ASIC1a, ASIC3, and heteromeric ASIC1a+3 with IC 50 values ranging from 0.61 to 2.2 μM. NS383 is well tolerated and capable of reversing pathological painlike behaviors, presumably via peripheral actions, but possibly also via actions within central pain circuits [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 309711-59-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-131879. | |
| NS3861 | NS3861 is an agonist of nicotinic acetylcholine receptors ( nAChRs ) and binds with high affinity to heteromeric α3β4 nAChR. The binding K i values of 0.62, 25, 7.8, 55 nM for α3β4, α3β2, α4β4, α4β2, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 216853-59-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110121A. | |
| NS 3861 | NS 3861 is an α3β2 full agonist with EC50 of 1.6 μM. It is also an α3β4 partial agonist with EC50 of 1 μM. Synonyms: NS3861; NS-3861; NS 3861; 3-(3-Bromo-2-thienyl)-8-methyl-8-azabicyclo[3.2.1]oct-2-ene fumarate. Grades: ≥98% by HPLC. CAS No. 216853-60-0. Molecular formula: C12H14BrNS.C4H4O4. Mole weight: 400.29. | |
| NS3861 fumarate | NS3861 fumarate is an agonist of nicotinic acetylcholine receptors ( nAChRs ) and binds with high affinity to heteromeric α3β4 nAChR. The binding K i values of 0.62, 25, 7.8, 55 nM for α3β4, α3β2, α4β4, α4β2, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 216853-60-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110121. | |
| Ns-398 | Heterocyclic Organic Compound. CAS No. 123653-11-2. Molecular formula: C13H18N2O5S. Mole weight: 314.36. Purity: >99 %. Catalog: ACM123653112. | |
| NS 398 | NS 398. Group: Biochemicals. Grades: Purified. CAS No. 123653-11-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NS 398 | NS 398 is a selective COX-2 inhibitor. Uses: Cyclooxygenase inhibitors. Synonyms: NS-398; NS 398; NS398. N-[2-Cyclohexyloxy-4-nitrophenyl]methanesulfonamide. CAS No. 123653-11-2. Molecular formula: C13H18N2O5S. Mole weight: 314.36. | |
| NS-398 | NS-398 is a non-steroidal an-inflammatory agent with analgesic and antipyretic effects, and selectively inhibits prostaglandin G/H synthase 2/cyclooxygenase 2 ( COX-2 ) activity, with an IC 50 of 3.8 μM, and has no effect on COX-1 at 100 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 123653-11-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13913. | |
| NS-398 (NS398, NS 398) | NS-398 (NS398, NS 398). Group: Biochemicals. Alternative Names: N- (2-cyclohexyloxy-4-nitrophenyl) methanesulfonamide. Grades: Highly Purified. CAS No. 123653-11-2. Pack Sizes: 50mg. Molecular Formula: C13 H18 N2O5, Molecular Weight: 314.4. US Biological Life Sciences. | Worldwide |
| NS-5 | NS-5 is a beta-lactam antibiotic produced by Streptomyces cattaleya. It inhibits gram-positive, gram-negative bacteria and beta-lactamase. Molecular formula: C11H16N2O3S. Mole weight: 256.32. | |
| NS 5806 | NS5806 is a KV4.3 channel activator. It can mediate the transient outward K+ current (Ito). Synonyms: NS-5806; NS 5806; NS5806; N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[2,4-dibromo-6-(2H-tetrazol-5-yl)phenyl]urea. Grades: ≥99% by HPLC. CAS No. 426834-69-7. Molecular formula: C16H8Br2F6N6O. Mole weight: 574.07. | |
| NS 5806 | NS 5806. Group: Biochemicals. Grades: Purified. CAS No. 426834-69-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NS6180 | NS6180 is a potent KCa3.1 channel blocker (IC50 values are 9, 14 and 15 nM for rat, human and mouse erythrocyte KCa3.1 channels respectively). NS6180 prevents T-cell activation and inflammation in a rat model of inflammatory bowel disease. Synonyms: NS6180; NS-6180; NS 6180. Grades: 98%. CAS No. 353262-04-1. Molecular formula: C16H12F3NOS. Mole weight: 323.33. | |
| NS 6180 | NS 6180. Group: Biochemicals. Grades: Purified. CAS No. 353262-04-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NS-638 | NS-638 is a small nonpeptide Ca(2+)-channel blocker. Synonyms: 1-[(4-chlorophenyl)methyl]-5-(trifluoromethyl)benzimidazol-2-amine; 2-amino-1-(4-chlorobenzyl)-5-trifluoromethylbenzimidazole; NS 638; NS-638. CAS No. 150493-34-8. Molecular formula: C15H11ClF3N3. Mole weight: 325.72. | |
| NS 6740 | NS 6740 is an α7 nAChR partial agonist displaying anti-inflammatory activity. It reduces LPS-induced TNF-α release from microglia enriched cultures. Synonyms: 1,4-Diazabicyclo[3.2.2]non-4-yl[5-[3-(trifluoromethyl)phenyl]-2-furanyl]methanone hydrochloride. Grades: ≥98% by HPLC. CAS No. 753499-14-8. Molecular formula: C19H19F3N2O2·HCl. Mole weight: 400.82. | |
| NS 8593 hydrochloride | NS8593 HCl is a selective KCa2 channel negative modulator. Synonyms: NS 8593 hydrochloride; NS8593 hydrochloride; NS-8593 hydrochloride; N-[(1R)-1,2,3,4-Tetrahydro-1-naphthalenyl]-1H-benzimidazol-2-amine hydrochloride. Grades: ≥98% by HPLC. CAS No. 875755-24-1. Molecular formula: C17H17N3.HCl. Mole weight: 299.8. | |
| NS8593 hydrochloride | NS8593 hydrochloride is a potent and selective small conductance Ca 2+ -activated K + channels (SK channels) inhibitor. NS8593 hydrochloride reversibly inhibits SK3 -mediated currents with a K d value of 77 nM. NS8593 hydrochloride inhibits all the SK1-3 subtypes Ca 2+ -dependently ( K d s of 0.42, 0.60, and 0.73 μM, respectively, at 0.5 μM Ca 2+ ), and does not affect the Ca 2+ -activated K + channels of intermediate and large conductance (hIK and hBK channels, respectively) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 875755-24-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-110105. | |
| NS8593 ((R)-N-(Benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphthylamine) | An aminobenzimidazole derivative that selectively and reversibly blocks small conductance Ca2+-activated K+ channels (SK1-3; =420nM, 600nM, and 730nM for SK1, SK2, SK3, respectively) in a Ca2+-dependent manner. It mediates channel gating by interacting with gating structures deep within the inner pore vestibule where Ser507 and Ala532 are deemed to be important for inhibition. Interacts at a site that is distinct from the apamin binding site in SK channels. Can access high-affinity binding sites from both the inside and outside of the cell membrane. Does not affect QT intervals, but prolongs the atrial effective refractive period and prevents acetylcholine-induced atrial fibrillations in ex vivo and in vivo models. Also shown to reversibly block TRPM7 channel (IC50=1.6mM) in smooth muscle cells, primary podocytes, HEK293 cells expressing TRPM7, and ventricular myocytes in a Mg2+-dependent manner and blocks the motility of cells in culture. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| NS 9283 | NS 9283. Group: Biochemicals. Grades: Purified. CAS No. 913830-15-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
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