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| Product | Description | |
|---|---|---|
| NS 398 | NS 398 is a selective COX-2 inhibitor. Uses: Cyclooxygenase inhibitors. Synonyms: NS-398; NS 398; NS398. N-[2-Cyclohexyloxy-4-nitrophenyl]methanesulfonamide. CAS No. 123653-11-2. Molecular formula: C13H18N2O5S. Mole weight: 314.36. |  |
| NS-398 | NS-398 is a non-steroidal an-inflammatory agent with analgesic and antipyretic effects, and selectively inhibits prostaglandin G/H synthase 2/cyclooxygenase 2 ( COX-2 ) activity, with an IC 50 of 3.8 μM, and has no effect on COX-1 at 100 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 123653-11-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13913. |  |
| NS-398 (NS398, NS 398) | NS-398 (NS398, NS 398). Group: Biochemicals. Alternative Names: N- (2-cyclohexyloxy-4-nitrophenyl) methanesulfonamide. Grades: Highly Purified. CAS No. 123653-11-2. Pack Sizes: 50mg. Molecular Formula: C13 H18 N2O5, Molecular Weight: 314.4. US Biological Life Sciences. |  Worldwide |
| NS-5 | NS-5 is a beta-lactam antibiotic produced by Streptomyces cattaleya. It inhibits gram-positive, gram-negative bacteria and beta-lactamase. Molecular formula: C11H16N2O3S. Mole weight: 256.32. | |
| NS 5806 | NS 5806. Group: Biochemicals. Grades: Purified. CAS No. 426834-69-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NS 5806 | NS5806 is a KV4.3 channel activator. It can mediate the transient outward K+ current (Ito). Synonyms: NS-5806; NS 5806; NS5806; N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[2,4-dibromo-6-(2H-tetrazol-5-yl)phenyl]urea. Grades: ≥99% by HPLC. CAS No. 426834-69-7. Molecular formula: C16H8Br2F6N6O. Mole weight: 574.07. | |
| NS6180 | NS6180 is a potent KCa3.1 channel blocker (IC50 values are 9, 14 and 15 nM for rat, human and mouse erythrocyte KCa3.1 channels respectively). NS6180 prevents T-cell activation and inflammation in a rat model of inflammatory bowel disease. Synonyms: NS6180; NS-6180; NS 6180. Grades: 98%. CAS No. 353262-04-1. Molecular formula: C16H12F3NOS. Mole weight: 323.33. | |
| NS 6180 | NS 6180. Group: Biochemicals. Grades: Purified. CAS No. 353262-04-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NS-638 | NS-638 is a small nonpeptide Ca(2+)-channel blocker. Synonyms: 1-[(4-chlorophenyl)methyl]-5-(trifluoromethyl)benzimidazol-2-amine; 2-amino-1-(4-chlorobenzyl)-5-trifluoromethylbenzimidazole; NS 638; NS-638. CAS No. 150493-34-8. Molecular formula: C15H11ClF3N3. Mole weight: 325.72. | |
| NS 6740 | NS 6740 is an α7 nAChR partial agonist displaying anti-inflammatory activity. It reduces LPS-induced TNF-α release from microglia enriched cultures. Synonyms: 1,4-Diazabicyclo[3.2.2]non-4-yl[5-[3-(trifluoromethyl)phenyl]-2-furanyl]methanone hydrochloride. Grades: ≥98% by HPLC. CAS No. 753499-14-8. Molecular formula: C19H19F3N2O2·HCl. Mole weight: 400.82. | |
| NS 8593 hydrochloride | NS8593 HCl is a selective KCa2 channel negative modulator. Synonyms: NS 8593 hydrochloride; NS8593 hydrochloride; NS-8593 hydrochloride; N-[(1R)-1,2,3,4-Tetrahydro-1-naphthalenyl]-1H-benzimidazol-2-amine hydrochloride. Grades: ≥98% by HPLC. CAS No. 875755-24-1. Molecular formula: C17H17N3.HCl. Mole weight: 299.8. | |
| NS8593 hydrochloride | NS8593 hydrochloride is a potent and selective small conductance Ca 2+ -activated K + channels (SK channels) inhibitor. NS8593 hydrochloride reversibly inhibits SK3 -mediated currents with a K d value of 77 nM. NS8593 hydrochloride inhibits all the SK1-3 subtypes Ca 2+ -dependently ( K d s of 0.42, 0.60, and 0.73 μM, respectively, at 0.5 μM Ca 2+ ), and does not affect the Ca 2+ -activated K + channels of intermediate and large conductance (hIK and hBK channels, respectively) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 875755-24-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-110105. | |
| NS8593 ((R)-N-(Benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphthylamine) | An aminobenzimidazole derivative that selectively and reversibly blocks small conductance Ca2+-activated K+ channels (SK1-3; =420nM, 600nM, and 730nM for SK1, SK2, SK3, respectively) in a Ca2+-dependent manner. It mediates channel gating by interacting with gating structures deep within the inner pore vestibule where Ser507 and Ala532 are deemed to be important for inhibition. Interacts at a site that is distinct from the apamin binding site in SK channels. Can access high-affinity binding sites from both the inside and outside of the cell membrane. Does not affect QT intervals, but prolongs the atrial effective refractive period and prevents acetylcholine-induced atrial fibrillations in ex vivo and in vivo models. Also shown to reversibly block TRPM7 channel (IC50=1.6mM) in smooth muscle cells, primary podocytes, HEK293 cells expressing TRPM7, and ventricular myocytes in a Mg2+-dependent manner and blocks the motility of cells in culture. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| NS 9283 | NS 9283 is an allosteric modulator of α4β2 receptor affecting the potency of acetylcholine related events. It can reduce the rate of recovery from desensitization and slow the rate of deactivation. Synonyms: NS9283; NS 9283; NS-9283; 3-[3-(3-Pyridinyl)-1,2,4-oxadiazol-5-yl]benzonitrile. Grades: ≥99% by HPLC. CAS No. 913830-15-6. Molecular formula: C14H8N4O. Mole weight: 248.24. | |
| NS 9283 | NS 9283. Group: Biochemicals. Grades: Purified. CAS No. 913830-15-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSAH | NSAH is a reversible and competitive nonnucleoside ribonucleotide reductase (RR) inhibitor, with cell-free IC 50 of 32 μM and cell-based IC 50 of ~250 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1099592-35-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114503. | |
| N-Salicylideneaniline | N-Salicylideneaniline. Group: Biochemicals. Alternative Names: N-Salicylalaniline. Grades: Highly Purified. CAS No. 779-84-0. Pack Sizes: 10g, 25g, 50g, 100g, 250g. US Biological Life Sciences. | Worldwide |
| N-Salicylidene p-bromoaniline | N-Salicylidene p-bromoaniline. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SALICYLIDENE-(P-BROMOANIL);SALICYLIDENE P-BROMOANILINE;TIMTEC-BB SBB007908;O-[N-(P-BROMOPHENYL)FORMIMIDOYL]PHENOL;N-SALICYLIDENE P-BROMOANILINE;2-(((4-bromophenyl)imino)methyl)-pheno;2-(((4-bromophenyl)imino)methyl)phenol;2-((E)-[(4-Bromophenyl)imino]met. Product Category: Heterocyclic Organic Compound. CAS No. 886-34-0. Molecular formula: C13H10BrNO. Mole weight: 276.13. Purity: 0.96. IUPACName: 6-[(4-bromoanilino)methylidene]cyclohexa-2,4-dien-1-one. Canonical SMILES: C1=CC(=CNC2=CC=C(C=C2)Br)C(=O)C=C1. Density: 1.385g/cm³. Product ID: ACM886340. Alfa Chemistry ISO 9001:2015 Certified. |  |
| N-Salicyloyltryptamine | N-Salicyloyltryptamine acts on voltage-dependent Na + , Ca 2+ , and K + ion channels inhibitor. N-Salicyloyltryptamine inhibits K + currents with an IC 50 value of 34.6 μM ( I to ). N-Salicyloyltryptamine also exhibits anticonvulsant, anti-inflammatory, analgesic, and vasorelaxation effect [1] - [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 31384-98-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-147377. | |
| NSC 109555 | NSC 109555. Group: Biochemicals. Alternative Names: 4,4'-Diacetyldiphenylurea bis(guanylhydrazone) Bismethanesulfonate; 2, 2'- [Carbonyl bis (imino-4, 1-phenyl ene ethyl idyne ) ] bis-hydrazinecarboximidam ide Dimethanesulfonate. Grades: Highly Purified. CAS No. 15427-93-7. Pack Sizes: 10mg. Molecular Formula: C21H32N10O7S2, Molecular Weight: 600.669999999999. US Biological Life Sciences. | Worldwide |
| NSC 109555 dimesylate | NSC 109555 is a potent and selective inhibitor of checkpoint kinase 2 (Chk2), displaying no effect against other kinases. It inhibits H1 phosphorylation and attenuates mitochondrial ATP synthesis. NSC 109555 can be used in cancer therapy. Synonyms: DDUG; NCI C04808; Carbanilide, 4,4'-diacetyl-, 4,4'-bis(amidinohydrazone), dimethanesulfonate. CAS No. 15427-93-7. Molecular formula: C19H24N10O·2CH3SO3H. Mole weight: 600.7. | |
| NSC 109555 ditosylate | NSC-109555 Ditosylate is an ATP-competitive Chk2 inhibitor with IC50 value of 0.2 μM. It acts by inhibiting histone H1 phosphorylation and attenuating mitochondrial ATP synthesis. It is an antileukemic agent. Synonyms: NSC-109555 Ditosylate; NSC 109555 Ditosylate; NSC109555 Ditosylate; 4,4'-diacetyldiphenylurea bis(guanylhydrazone) ditosylate. Grades: ≥98% by HPLC. CAS No. 66748-43-4. Molecular formula: C19H24N10O.2C7H8O3S. Mole weight: 752.86. | |
| NSC 109555 ditosylate | NSC 109555 ditosylate. Group: Biochemicals. Grades: Purified. CAS No. 66748-43-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC12 | NSC12 is an extracellular trap for fibroblast growth factor 2 (FGF2). It binds FGF2 with Kd value of 51 μM and interferes with its interaction with FGFR1 without affecting the ability of FGF2 to bind heparin or heparin sulfate proteoglycans. It also binds several other FGF isoforms and prevents them from forming HSPG/FGF/FGFR ternary complexes. It inhibits FGF-dependent angiogenesis and tumor cell proliferation in vitro and reduces tumor growth in mice. It inhibited the proliferation of different FGF-dependent tumour cell lines, but had no inhibitory effect on FGF-independent tumour cells expressing a constitutively active FGFR1. It was shown to inhibit FGFR phosphorylation, angiogenesis and primary and metastatic tumour growth of FGF-dependent human and mouse cancer cells in vivo. It has significant implications in cancer therapy. Uses: Nsc12 has significant implications in cancer therapy. Synonyms: NSC-12; NSC 12; NSC12; NSC 172285; NSC-172285; NSC172285; 21- (Hydroxy (bistrifluoromethyl)methyl)pregnane-3, 20-diol; Pregn-5-ene-3, 20-diol, 21-(2-hydroxy-1,1,1,3,3,3-hexafluoro-2-propyl)-;LS-118618;4,4,4-Trifluoro-1-[(8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-3-(trifluoromethyl)butane-1,3-diol;NSC-12;NSC-172285;NSC172285;(R)-4,4,4-trifluoro-1-((3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-3-(trifluoromethyl)butane-1,3-diol. Grades: >98 %. CAS No. 102586-30-1. Molecular formula: C24H34F6O3. Mole weight: 484.52. | |
| NSC125066 | NSC125066 Inhibitor. Uses: Scientific use. Product Category: T6116. CAS No. 9041-93-4. |  |
| NSC134754 | NSC134754 is a Heat Shock Factor 1 (HSF1) inhibitor. It can induce inhibition of HSF1, SP1 and NF-κB triggers the loss of the natural killer cell-activating ligands MICA/B on human tumor cells. NSC134754 can also completely block HIF-1α induced by IGF-1 in HCT116 human colon carcinoma cells. Uses: Amti-tumor. Synonyms: NZ-28; NZ28; NZ 28; NSC 134754; NSC 134754; NSC134754. (S)-3-ethyl-9,10-dimethoxy-2-(((R)-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl)-1,6,7,11b-tetrahydro-4H-pyrido[2,1-a]isoquinoline. Grades: 98%. CAS No. 75041-32-6. Molecular formula: C27H34N2O2. Mole weight: 418.58. | |
| NSC 146109 hydrochloride | NSC 146109 hydrochloride is a genotype-selective antitumor agent. It can activate p53-dependent transcription. Synonyms: NSC 146109 hydrochloride; NSC146109 hydrochloride; NSC-146109 hydrochloride; (10-Methyl-9-anthracenyl) methyl carbamimidothioic acid ester hydrochloride. Grades: ≥99% by HPLC. CAS No. 59474-01-0. Molecular formula: C17H16N2S.HCl. Mole weight: 316.85. | |
| NSC 146109 hydrochloride | NSC 146109 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 59474-01-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC 177223 | NSC 177223. Group: Biochemicals. Alternative Names: 4-Amino-5,8-dihydro-5-oxo-8- β-D-ribofuranosyl-pyrido[2,3-d]pyrimidine-6-carboxamide; API-1. Grades: Highly Purified. CAS No. 36707-00-3. Pack Sizes: 5mg. Molecular Formula: C13H15N5O6, Molecular Weight: 337.29. US Biological Life Sciences. | Worldwide |
| NSC 185058 | NSC 185058 is an inhibitor of ATG4B that inhibits ATG4B activity in vitro and in cells with no effect against MTOR and PtdIns3K. It inhibited autophagy and exhibited a negative impact on the development of Saos-2 osteosarcoma tumors in vivo. Synonyms: N-(pyridin-2-yl)pyridine-2-carbothioamide. Grades: ≥98%. CAS No. 39122-38-8. Molecular formula: C11H9N3S. Mole weight: 215.3. | |
| NSC 207895 | NSC 207895 suppresses MDMX with IC50 of 2.5 μM, leading to enhanced p53 stabilization/activation and DNA damage, and also regulates MDM2, an E3 ligase. Synonyms: NSC 207895; NSC-207895; NSC207895; XI-006; XI006; XI 006. Grades: >98%. CAS No. 58131-57-0. Molecular formula: C11H13N5O4. Mole weight: 279.25. | |
| NSC 210902 | NSC 210902 is an ATP-competitive inhibitor of casein kinase 2 (CK2). It inhibits CK2 which is increased in tumor tissues, suppressing the proliferation of cancer cells. Synonyms: 4-oxo-1,4-dihydrobenzo[h]quinoline-3-carboxylic acid. Grades: ≥95%. CAS No. 51726-83-1. Molecular formula: C14H9NO3. Mole weight: 239.2. | |
| NSC 228155 | NSC 228155 is an EGFR activator that binds to the dimerization domain II of sEGFR. It inhibits KIX-KID interaction with IC50 value of 0.36 μM. Synonyms: NSC228155; NSC-228155; 7-nitro-4-(1-oxidopyridin-1-ium-2-yl)sulfanyl-2,1,3-benzoxadiazole. CAS No. 113104-25-9. Molecular formula: C11H6N4O4S. Mole weight: 290.25. | |
| NSC 23005 sodium | NSC23005 sodium is a p18INK inhibitor. It can promote hematopoietic stem cell expansion with ED50 of 5.21 nM. Synonyms: NSC 23005 sodium; NSC23005 sodium; NSC-23005 sodium; 4-[(Cyclohexylamino)sulfonyl]benzoic acid sodium salt. Grades: ≥99% by HPLC. CAS No. 1796596-46-7. Molecular formula: C13H16NNaO4S. Mole weight: 305.33. | |
| NSC 23005 Sodium Salt | Cas No. 6314-70-1. | |
| NSC 23005 Sodium Salt | NSC 23005 Sodium Salt is used to perpare sodium sodium cyclohexyl aminosulfonyl benzoate as p18 micromolecule inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1796596-46-7. Pack Sizes: 1mg, 5mg. Molecular Formula: C13H16NNaO4S, Molecular Weight: 305.33. US Biological Life Sciences. | Worldwide |
| NSC232003 | NSC232003, a uracil derivative freely available by the NCI/DTP Repository, is an effective DNA methylation inhibitor. Synonyms: NSC232003; NSC 232003; NSC-232003; (5Z)-5-[1-(hydroxyamino)ethylidene]pyrimidine-2,4-dione. CAS No. 1905453-18-0. Molecular formula: C6H7N3O3. Mole weight: 169.14. | |
| NSC 23766 | NSC 23766 is a specific inhibitor of the binding and activation of RAC GTPase. It does not inhibit the closely related targets, Cdc42 or RhoA. Synonyms: NSC 23766; NSC23766; NSC-23766. Grades: >98%. CAS No. 733767-34-5. Molecular formula: C24H35N7. Mole weight: 421.58. | |
| NSC 23766 trihydrochloride | NSC 23766 is a Rac GTPase inhibitor that suppresses Rac GTPase activation by the Rac-specific GEFs. It shows an inhibitory activity in the influenza virus, as well as the anchorage-independent growth and invasion phenotypes of human prostate cancer PC-3 cells. Synonyms: NSC 23766 (trihydrochloride); NSC23766 (trihydrochloride); NSC-23766 (trihydrochloride); N6-(2-((5-(Diethylamino)pentan-2-yl)amino)-6-methylpyrimidin-4-yl)-2-methylquinoline-4,6-diamine Trihydrochloride. Grades: ≥98%. CAS No. 1177865-17-6. Molecular formula: C24H38Cl3N7. Mole weight: 530.967. | |
| NSC23925 | NSC23925 is a novel, selective and effective P-glycoprotein ( Pgp ) inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 858474-14-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-19626. | |
| NSC 23925 | NSC 23925 is a potent plasma membrane glycoprotein 1 (Pgp1) inhibitor that reverses multidrug resistance (MDR1) mediated by Pgp1 without inhibitory effect against MRP or BCRP-mediated MDR1. NSC 23925 can prevent MDR1 in ovarian cancer both in vitro and in vivo. Synonyms: (2-(4-methoxyphenyl)quinolin-4-yl)(piperidin-2-yl)methanol dihydrochloride. Grades: ≥98%. CAS No. 858474-14-3. Molecular formula: C22H24N2O2·2HCl. Mole weight: 421.4. | |
| NSC 245214 | NSC 245214 is a thienyl cycloalkanone that is part of the US National Cancer Institute small molecule repository. The biological activity of this compound has not been reported. Group: Biochemicals. Alternative Names: 2-(3,5-dinitro-2-thienyl)-cyclohexanone. Grades: Highly Purified. CAS No. 31554-45-7. Pack Sizes: 1mg, 5mg, 10mg, 25mg. Molecular Formula: C10H10N2O5S, Form: Supplied as a crystalline. US Biological Life Sciences. | Worldwide |
| NSC-26326 | NSC-26326 Inhibitor. Uses: Scientific use. Product Category: T6407. CAS No. 4707-32-8. | |
| NSC 280449 | NSC 280449 is a derivative of Tromethamine (T892600); a compound that is widely used in biochemistry and molecular biology. In medicine, Tromethamine is used as an alternative to sodium bicarbonate in the treatment of metabolic acidosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 60204-53-7. Pack Sizes: 100mg, 500mg. Molecular Formula: C10H17NO3, Molecular Weight: 199.25. US Biological Life Sciences. | Worldwide |
| NSC 295642 | NSC 295642. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NSC 295642, [1-(2-pyridinyl)ethylidene]-Hydrazinecarbodithioic acid, phenylmethyl ester, copper complex, 77111-29-6, Bis-[chloro[phenylmethyl [1-(2-pyridinyl)ethylidene]hydrazinecarbodithioato-N2,N2 inverted exclamation marka,S1 inverted exclamation mark ]-copper], Cu(II) complex of the Schiff base product of condensation of S-benzyl dithiocarbazate and 2-acetylpyridine. Product Category: Heterocyclic Organic Compound. CAS No. 77111-29-6. Molecular formula: C15H14ClCuN3S2. Mole weight: 798.84. Purity: 0.96. IUPACName: (E)-benzylsulfanyl-[(E)-1-pyridin-2-ylethylidenehydrazinylidene]-sulfidomethane;chlorocopper(1+). Canonical SMILES: CC(=NN=C([S-])SCC1=CC=CC=C1)C2=CC=CC=N2.Cl[Cu+]. Product ID: ACM77111296. Alfa Chemistry ISO 9001:2015 Certified. Categories: DTXSID20444568. | |
| NSC305787 | NSC305787 is a small molecule inhibitor of PKC. Its IC50 value is 8.3 μM, 9.4 μM, 55 μM for PKC&Lota; phosphorylation of recombinant ezrin, moesin and radixin. It is proved a novel targeted therapy which could inhibit ezrin protein as an approach to prevent tumor metastasis in vitro. It could inhibited T567 phosphorylation and actin binding of endogenous ezrin at 10 μM without altering cellular ezrin levels and inhibit the lung metastases growth of high-ezrin-expressing K7M2 OS cells in this organ culture assay. It cause reduced cell motility phenotypes in zebrafish in vivo. Uses: Nsc305787 is proved a novel targeted therapy which could inhibit ezrin protein as an approach to prevent tumor metastasis in vitro. it could inhibited t567 phosphorylation and actin binding of endogenous ezrin at 10 μm without altering cellular ezrin levels and inhibit the lung metastases growth of high-ezrin-expressing k7m2 os cells in this organ culture assay. Synonyms: NSC 305787; NSC-305787; NSC 305787. Grades: >98%. CAS No. 785718-37-8. Molecular formula: C25H30Cl2N2O. Mole weight: 445.42. | |
| NSC305787 hydrochloride | NSC305787 hydrochloride is a small molecule inhibitor of PKC (IC50=8.3 μM) that directly inhibits ezrin protein as an approach to prevent tumor metastasis. Uses: A small molecule inhibitor of pkc. Synonyms: NSC-305787 Hydrochloride; NSC 305787 Hydrochloride; NSC305787 Hydrochloride; NSC-305787 HCl; NSC 305787 HCl; NSC305787 HCl; [2-(Adamantan-1-yl)-6,8-dichloro-4-quinolinyl](2-piperidinyl)methanol hydrochloride;[2-(Adamantan-1-yl)-6,8-dichloro-4-quinolinyl](2-piperidinyl)methanol hydrochloride. Grades: ≥95%. CAS No. 53868-26-1. Molecular formula: C25H31Cl3N2O. Mole weight: 481.89. | |
| NSC 319726 | NSC 319726. Group: Biochemicals. Grades: Purified. CAS No. 71555-25-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC 319726 | NSC319726 is a p53(R175) mutant reactivator, exhibits growth inhibition in cells expressing mutant p53, with IC50 of 8 nM for p53(R175) mutant, shows no inhibition for p53 wild-type cells. Synonyms: NSC-26386; NSC-319726; NSC 26386; NSC 319726; NSC26386; NSC319726. Grades: >98%. CAS No. 71555-25-4. Molecular formula: C11H14N4S. Mole weight: 234.32. | |
| NSC 33994 | NSC 33994. Group: Biochemicals. Grades: Purified. CAS No. 82058-16-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC 33994 | NSC-33994 is a selective inhibitor of JAK2 with IC50 of 60 nM. Synonyms: NSC-33994; NSC 33994; NSC33994; E-4,4'-(1,2-Diethyl-1,2-ethenediyl)bis[2-[(diethylamino)methyl]phenol. Grades: ≥98% by HPLC. CAS No. 82058-16-0. Molecular formula: C28H42N2O2. Mole weight: 438.65. | |
| NSC-33994 | NSC-33994 is novel inhibitor of JAK2 tyrosine kinase (Janus kinase 2 ). Janus kinase 2 (JAK2) plays a crucial role in the pathomechanism of myeloproliferative disorders and hematological malignancies. Group: Biochemicals. Alternative Names: 4, 4'-[ (1E) -1, 2-Diethyl-1, 2-ethenediyl]bis[2-[ (diethylamino) methyl]phenol; (E) -4, 4'- (1, 2-Diethyl-1, 2-ethenediyl) bis[2-[ (diethylamino) methyl]phenol. Grades: Highly Purified. CAS No. 82058-16-0. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| NSC348884 | NSC 348884 is a putative inhibitor of nucleophosmin (NPM). It is a small molecule that inhibits the formation of nucleophosmin dimers by disrupting a defined hydrophobic pocket required for oligomerization. It can inhibit cell proliferation,up-regulates p53 and induce apoptosis in various cancer cell lines with IC50 values ranging from 1.4-4 μM. It disrupts nucleophosmin oligomer formation by native polyacrylamide gel electrophoresis assay. Uses: Nsc 348884 inhibits the formation of nucleophosmin dimers. it can inhibit cell proliferation,up-regulates p53 and induce apoptosis in various cancer cell line. it disrupts nucleophosmin oligomer formation by native polyacrylamide gel electrophoresis assay. Synonyms: NSC348884; NSC 348884; NSC-348884; N1,N1,N2,N2-Tetrakis[(6-methyl-1H-benzimidazol-2-yl)methyl]-1,2-ethanediamine;1,2-EthanediaMine, N,N,N',N'-tetrakis[(5-Methyl-1H-benziMidazol-2-yl)Methyl]- ;N,N,N',N'-tetrakis[(6-methyl-1H-benzimidazol-2-yl)methyl]ethane-1,2-diamine. Grades: >98%. CAS No. 81624-55-7. Molecular formula: C38H40N10. Mole weight: 636.79. | |
| NSC 3852 | NSC 3852. Group: Biochemicals. Grades: Purified. CAS No. 3565-26-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC 3852 | NSC 3852 is a histone deacetylase inhibitor. It is shown to have cell differentiation and antiproliferative activity in human breast cancer cells. Synonyms: NSC 3852; NSC3852; NSC-3852; 5-Nitroso-8-quinolinol. Grades: ≥95% by HPLC. CAS No. 3565-26-2. Molecular formula: C9H6N2O2. Mole weight: 174.16. | |
| NSC 405020 | NSC-405020 is a novel small molecule inhibitor of MT1-MMP that specifically targets PEX domain rather than the catalytic domain of MT1-MMP with IC50 >100 μM and does not inhibit the catalytic activity of MT1-MMP or MMP-2. Synonyms: TWS119; TWS 119; TWS-119. CAS No. 7497-7-6. Molecular formula: C12H15Cl2NO. Mole weight: 260.158. | |
| NSC 405020 | NSC 405020. Group: Biochemicals. Grades: Purified. CAS No. 7497-7-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC-41589 | N-[2-(methylsulfanyl) phenyl]acetamide. Synonyms: NSC-41589; NSC 41589; NSC41589. Grades: >98%. CAS No. 6310-41-4. Molecular formula: C9H11NOS. Mole weight: 181.25. | |
| Nsc42165 | Nsc42165. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Nsc42165. Product Category: Heterocyclic Organic Compound. CAS No. 17596-06-4. Mole weight: 0. Product ID: ACM17596064. Alfa Chemistry ISO 9001:2015 Certified. Categories: 4,4'-(Diazoamino)dibenzenesulfonic acid. | |
| NSC 42834 | A cell-permeable pyridinylbutanone compound that inhibits cellular autophosphorylation of both the wild-type Jak2 and the constitutively active V167F mutant (IC50 = 15 & 28 μM, respectively, with WT- & V617F-transfected BSC-40 cells), while exhiting no effect against cellular Tyk2 autophosphorylation in COS cells or c-Src kinase in cell-free kinase assays. Z3 suppresses the Jak2-V167F-dependent proliferation of the erythroleukemia cell line HEL by blocking the G1-S transition and is shown to effectively reduce the cytokine-stimulated growth of both Jak2-V617F-positive and Jak2-F537I-positive primary hematopoietic progenitor cells from myeloproliferative disorder patients. Synonyms: NSC 42834; NSC-42834; NSC42834; Z3; 1-Butanone, 2-methyl-1-phenyl-4-(2-pyridinyl)-2-[2-(2-pyridinyl)ethyl]-. Grades: >98%. CAS No. 195371-52-9. Molecular formula: C23H24N2O. Mole weight: 344.45. | |
| NSC5844 | NSC5844 is a CCR1 agonist and a bisquinoline compound. Synonyms: N,N'-bis(7-chloroquinolin-4-yl)ethane-1,2-diamine; NSC5844; NSC-5844; NSC 5844; RE640; RE-640; R E640. CAS No. 140926-75-6. Molecular formula: C20H16Cl2N4. Mole weight: 383.27. | |
| NSC59984 | NSC59984 is a p53 pathway activator via induction of mutant p53 protein degradation and p73 activation. Synonyms: NSC-59984; NSC 59984. Grades: 98%. CAS No. 803647-40-7. Molecular formula: C12H15N3O4. Mole weight: 265.27. | |
| NSC59984 | NSC59984 induces mutant p53 protein degradation via MDM2 and the ubiquitin-proteasome pathway [1]. NSC59984 acts by targeting GOF-mutant p53 and stimulates p73 to restore the p53 pathway signaling [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 803647-40-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19726. | |
| NSC-601980 analog | NSC-601980 analog is the analog of the NSC601980, which shows antitumor activity in the yeast screening experiment. Synonyms: NSC601980 analog; NSC 601980 analog; NSC-601980 analog. Grades: >98%. CAS No. 91757-46-9. Molecular formula: C15H14N4. Mole weight: 250.30. | |
| NSC 617145 | NSC 617145 is a werner syndrome helicase inhibitor with IC50 value of 250 nM. It is used as an antineoplastic. Synonyms: 1,1'-(2,2-dimethyl-1,3-propanediyl)bis[3,4-dichloro-1H-Pyrrole-2,5-dione. Grades: ≥98% by HPLC. CAS No. 203115-63-3. Molecular formula: C13H10Cl4N2O4. Mole weight: 400.04. | |
| NSC 617145 | NSC 617145. Group: Biochemicals. Grades: Purified. CAS No. 203115-63-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC 624206 | NSC 624206 is a ubiquitin-activating enzyme inhibitor that blocks ubiquitin-thioester formation with IC50 value of 13 μM. Synonyms: NSC 624206; NSC624206; NSC-624206; N-[2-[[(4-Chlorophenyl)methyl]dithio]ethyl]-1-decanamine hydrochloride. Grades: ≥98% by HPLC. CAS No. 13116-77-3. Molecular formula: C19H32ClNS2.HCl. Mole weight: 410.51. | |
| NSC 624206 | NSC 624206. Group: Biochemicals. Grades: Purified. CAS No. 13116-77-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Nsc 625987 | NSC 625987 is a specific and high-affinity CDK4 inhibitor with an IC50 of 0.2 μM for CDK4:cyclin D1. NSC 625987 shows >500-fold selectivity for CDK4 over CDK2. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 141992-47-4. Molecular formula: C15H13NO2S. Mole weight: 271.339. Purity: >98 %. Product ID: ACM141992474. Alfa Chemistry ISO 9001:2015 Certified. | |
| NSC 625987 | NSC 625987. Group: Biochemicals. Grades: Purified. CAS No. 141992-47-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
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