A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Oclacitinib, also known as PF03394197, is a novel Janus kinase inhibitor with activity against cytokines involved in allergy. Oclacitinib inhibited JAK family members by 50% at concentrations (IC50 's) ranging from 10 to 99 nM and did not inhibit a panel of 38 non-JAK kinases (IC50 's > 1000 nm). Oclacitinib was most potent at inhibiting JAK1 (IC50 = 10 nm). Oclacitinib also inhibited the function of JAK1-dependent cytokines involved in allergy and inflammation (IL-2, IL-4, IL-6, and IL-13) as well as pruritus (IL-31) at IC50 's ranging from 36 to 249 nm. Oclacitinib had minimal effects on cytokines that did not activate the JAK1 enzyme in cells (erythropoietin, granulocyte/macrophage colony-stimulating factor, IL-12, IL-23; IC50 's > 1000 nm). These results demonstrate that oclacitinib is a targeted therapy that selectively inhibits JAK1-dependent cytokines involved in allergy, inflammation, and pruritus and suggests these are the mechanisms by which oclacitinib effectively controls clinical signs associated with allergic skin disease in dogs. Synonyms: Cyclohexanemethanesulfonamide, N-methyl-4-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-, trans-; trans-N-Methyl-4- (methyl-7H-pyrrolo[2, 3-d]pyrimidin-4-ylamino) cyclohexanemethanesulfonamide; JAKi; PF 03394197. Grades: 98%. CAS No. 1208319-26-9. Molecular formula: C15H23N5O2S. Mole weight: 337.44.
Oclacitinib
Oclacitinib is a novel JAK inhibitor. Oclacitinib is most potent at inhibiting JAK1 ( IC 50 =10 nM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-03394197. CAS No. 1208319-26-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13577.
Oclacitinib Maleate
Oclacitinib maleate was the first selective Janus kinase (JAK) inhibitor to be developed for dogs. Oclacitinib is most potent at inhibiting JAK1 (IC50=10 nM). Synonyms: Cyclohexanemethanesulfonamide, N-methyl-4-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-, trans-, (2Z)-2-butenedioate (1:x); Apoquel; Oclacitinib maleate (1:x); PF 03394197-11; trans-N-Methyl-4- (methyl-7H-pyrrolo[2, 3-d]pyrimidin-4-ylamino) cyclohexanemethanesulfonamide maleate (1:x); N-methyl-1- ( (1r, 4r) -4- (methyl (7H-pyrrolo[2, 3-d]pyrimidin-4-yl) amino) cyclohexyl) methanesulfonamide maleate. Grades: ≥95%. CAS No. 1208319-27-0. Molecular formula: C15H23N5O2S.xC4H4O4. Mole weight: 337.44 (free base).
o-Coumaric Acid 4-O- β-D-Glucuronide
o-Coumaric Acid 4-O- β-D-Glucuronide is a metabolite of either Coumarin (C755380) or o-Hydroxy-cinnamic Acid (614-60-8). Group: Biochemicals. Grades: Highly Purified. CAS No. 108884-00-0. Pack Sizes: 10mg, 25mg. Molecular Formula: C15H16O9, Molecular Weight: 340.28. US Biological Life Sciences.
Worldwide
o-Coumaric Acid 4-O- β-D-glucuronide-d4
o-Coumaric Acid 4-O- β-D-glucuronide-d4 is an isotopic analog of o-Coumaric Acid 4-O- β-D-Glucuronide (C755405), which is a metabolite of either Coumarin (C755380) or o-Hydroxy-cinnamic Acid (614-60-8). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C15H12D4O9, Molecular Weight: 344.31. US Biological Life Sciences.
Worldwide
ocrelizumab
Ocrelizumab is an anti-CD20 monoclonal antibody developed by Genentech to treat relapsing and primary progressive forms of multiple sclerosis (MS). Uses: The treatment of relapsing and primary progressive forms of multiple sclerosis (ms). Synonyms: Ocrevus. CAS No. 637334-45-3. Molecular formula: C6494H9978N1718O2014S46. Mole weight: 148000.
Ocrelizumab
Ocrelizumab (Ocrevus) is a humanized anti- CD20 monoclonal antibody. Ocrelizumab can induce B cell depletion and inhibit multiple sclerosis lesions in mice through antibody dependent cytotoxicity (ADCC) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 637334-45-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9960.
o-Cresol
o-Cresol is a compound used as a disinfectant and have also been used as antiseptic in surgery. Group: Biochemicals. Alternative Names: 1-Hydroxy-2-methylbenzene; 1-Methyl-2-hydroxybenzene; 2-Cresol; 2-Hydroxytoluene; 2-Methylphenol; NSC 23076; NSC 36809; o-Cresylic Acid; o-Hydroxytoluene; o-Methylphenol; o-Methylphenylol; o-Oxytoluene; o-Toluol; 2-Methylphenol. Grades: Highly Purified. CAS No. 95-48-7. Pack Sizes: 10g. US Biological Life Sciences.
Worldwide
o-Cresol
O-cresol appears as colorless or yellow to brown-yellow or pinkish colored liquid with a phenol-like odor. Toxic by ingestion and/or skin absorption. May have a flash point between 100 and 199°F. Causes burns to skin, eyes and mucous membranes. Insoluble in water.;Liquid;Liquid; OtherSolid;Solid;Solid;COLOURLESS CRYSTALS WITH CHARACTERISTIC ODOUR. TURNS DARK ON EXPOSURE TO AIR AND LIGHT.;Colourless to pale brown crystals;White crystals with a sweet, tarry odor. [Note: A liquid above 88°F.]. Group: Polymers. Product ID: 2-methylphenol. Molecular formula: 108.14g/mol. Mole weight: C7H8O;CH3C6H4OH;C7H8O. CC1=CC=CC=C1O. InChI=1S/C7H8O/c1-6-4-2-3-5-7 (6)8/h2-5, 8H, 1H3. QWVGKYWNOKOFNN-UHFFFAOYSA-N.
o-Cresol
100g Pack Size. Group: Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials. Formula: C6H4(CH3)OH. CAS No. 95-48-7. Prepack ID 29263194-100g. Molecular Weight 108.14. See USA prepack pricing.
o-Cresol
500g Pack Size. Group: Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials. Formula: C6H4(CH3)OH. CAS No. 95-48-7. Prepack ID 29263194-500g. Molecular Weight 108.14. See USA prepack pricing.
Isotope labelled o-Cresol is a compound used as a disinfectant and have also been used as antiseptic in surgery. Group: Biochemicals. Alternative Names: 1-Hydroxy-2-methylbenzene-d7; 1-Methyl-2-hydroxybenzene-d7; 2-Cresol-d7; 2-Hydroxytoluene-d7; 2-Methylphenol-d7; NSC 23076-d7; NSC 36809-d7; o-Cresylic Acid-d7; o-Hydroxytoluene-d7; o-Methylphenol-d7; o-Methylphenylol-d7; o-Oxytoluene-d7; o-Toluol-d7; 2-Methylphenol-d7. Grades: Highly Purified. CAS No. 202325-50-6. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
o-Cresolphthalein
o-Cresolphthalein. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 25g, 100g, 250g, 1Kg. US Biological Life Sciences.
Worldwide
o-Cresolphthalein
25g Pack Size. Group: Stains & Indicators. Formula: C22H18O4. CAS No. 596-27-0. Prepack ID 15685521-25g. Molecular Weight 346.38 g/mol. See USA prepack pricing.
o-Cresolphthalein complexone
o-Cresolphthalein complexone is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells. Uses: Scientific research. Group: Fluorescent dye. CAS No. 2411-89-4. Pack Sizes: 1 g; 5 g; 10 g. Product ID: HY-D0250.
o-Cresolphthalein Complexone
5g Pack Size. Group: Ligands, Stains & Indicators. Formula: C32H32N2O12. CAS No. 2411-89-4. Prepack ID 20195051-5g. Molecular Weight 636.62. See USA prepack pricing.
o-Cresolphthalein Complexone sodium salt
5g Pack Size. Group: Analytical Reagents, Diagnostic Raw Materials, Stains & Indicators. Formula: C32H28N2O12Na4. CAS No. 62698-54-8. Prepack ID 37496183-5g. Molecular Weight 724.54. See USA prepack pricing.
O-Cresolphthalein complexone sodium salt
O-Cresolphthalein complexone sodium salt. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g, 250g, 1Kg. US Biological Life Sciences.
Oct-1-en-3-ol. CAS No. 3391-86-4. Kosher: Y. VIGON Item # 507895. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers, octenol, mushroom alcohol.
America & Internationally
Oct-1-en-3-ol
Oct-1-en-3-ol, a fatty acid fragrant, is a self-stimulating oxylipin messenger. Oct-1-en-3-ol serves as a signaling molecule in plant cellular responses, plant-herbivore interactions, and plant-plant interactions. Oct-1-en-3-ol causes dopamine neuron degeneration through disruption of dopamine handling [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 3391-86-4. Pack Sizes: 10 mM * 1 mL; 10 g; 25 g. Product ID: HY-W010410.
Octaacetyl Xylotriose is an intermediate in synthesizing Xylotriose, a newly developed xylo-oligosaccharide, usually produced from xylan by enzymic hydrolysis, with many beneficial biomedical and health effects. Synonyms: O-2,?3,?4-Tri-O-acetyl-β-D-xylopyranosyl-(1?4)?-O-2,?3-di-O-acetyl-β-D-xylopyranosyl-(1?4)?-D-xylopyranose 1,?2,?3-Triacetate; (3R,4S,5R)-5-(((2S,3R,4S,5R)-3,4-Diacetoxy-5-(((2S,3R,4S,5R)-3,4,5-triacetoxytetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2,3,4-triyl Triacetate. CAS No. 67226-05-5. Molecular formula: C31H42O21. Mole weight: 750.65.
Octachlorodibenzo-p-dioxin. Group: Biochemicals. Alternative Names: 1, 2, 3, 4, 6, 7, 8, 9-Octachlorodibenzo[b, e][1, 4]dioxin. Grades: Highly Purified. CAS No. 3268-87-9. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C12Cl8O2. US Biological Life Sciences.
Worldwide
Octacosamicin A
Octacosamicin A is originally isolated from Amycolatops azurea MG 398-hF9 (FERM P-8865). It has the function of resisting bacterium, yeast, and filamentous fungus, but the function of resisting bacterium is weak. Synonyms: Antibiotic MG 398HF9A; Glycine, N-(28-((aminoiminomethyl)hydroxyamino)-2,3,5,7-tetrahydroxy-1,19-dioxo-12,14,20,22-octacosatetraenyl)-. Grades: >95%. CAS No. 122005-25-8. Molecular formula: C31H52N4O9. Mole weight: 624.76.
Octacosamicin B
Octacosamicin B is originally isolated from Amycolatops azurea MG 398-hF9 (FERM P-8865). It has the function of resisting bacterium, yeast, and filamentous fungus, but the function of resisting bacterium is weak. CAS No. 122005-24-7. Molecular formula: C32H54N4O9. Mole weight: 638.79.
Octacosane-d 58 is the deuterium labeled Octacosane[1]. Octacosane is an endogenous metabolite with antibacterial activity. Octacosane shows high cytotoxicity against murine melanoma B16F10-Nex2 cells besides inducing protection against a grafted subcutaneous melanoma. Octacosane has the larvicidal activity against mosquito Culex quinquefasciatus with the LC50 concentration of 7.2 mg/l[2][3][4]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: n-Octacosane-d58; NSC 5549-d58. CAS No. 16416-33-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W272217S.
Octacosanoic acid
Octacosanoic acid is a very long-chain saturated fatty acid. It is the major component of D-003, a mixture of very long-chain aliphatic acids purified from sugar cane wax that has antiplatelet and cholesterol-lowering activities in animal models [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Montanic acid. CAS No. 506-48-9. Pack Sizes: 25 mg; 50 mg. Product ID: HY-N8425.
Octacosanol. Group: Biochemicals. Alternative Names: Montanyl alcohol; Cluytyl alcohol. Grades: Plant Grade. CAS No. 557-61-9. Pack Sizes: 20mg. Molecular Formula: C28H58O, Molecular Weight: 410.76. US Biological Life Sciences.
Worldwide
Octadearyl dimethyl ammonium chloride
Metal Plating, Electropolishing, Metal Reprocessing, Phase transfer media, Batteries Fuel Cells, Nanomaterials, Industrial Solvents, Nuclear Fuel Red Waste, Enzymatic Catalysis, Lubricants Heat Transfer and Solar Energy Conversion. Group: Ammonium ionic liquids. CAS No. 112-03-8. Molecular formula: C21H46N.Cl. Mole weight: 348.05. Purity: 98% min. ECNumber: 203-929-1. Catalog: ACM112038.
Octadecafluorooctane. Group: Biochemicals. Alternative Names: Perfluorooctane. Grades: Highly Purified. CAS No. 307-34-6. Pack Sizes: 10g, 25g, 50g, 100g, 250g. US Biological Life Sciences.
Worldwide
Octadecanal
Octadecanal is a long-chain aldehyde, present in both thigh and breast muscle [1]. Uses: Scientific research. Group: Natural products. CAS No. 638-66-4. Pack Sizes: 50 mg; 100 mg. Product ID: HY-W004307.
Octadecanaldehyde
Octadecanaldehyde used in the preparation of new anti-HIV Molokalamine derivatives. Also used in the preparation of fluorescently labelled dynamic amphiphiles for analysis of transmembrane ion transport, sensing and cellular uptake. Group: Biochemicals. Alternative Names: Octadecanal; Stearaldehyde; 1-Octadecanal; 1-Oxooctadecane; NSC 68100; Octadecanaldehyde; Octadecyl Aldehyde; Stearyl Aldehyde; n-Octadecanal. Grades: Highly Purified. CAS No. 638-66-4. Pack Sizes: 1g. US Biological Life Sciences.
Octadecane is an alkane that is used to store thermal energy at ambient temperature as a phase change material [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 593-45-3. Pack Sizes: 1 g. Product ID: HY-N6600.
Octadecanedioic acid (CAS# 871-70-5) is one of the fine particle pollutant emissions from the fireplace combustion of woods grown in Southern USA. Synonyms: 1,18-Octadecanedioic acid; 1,16-Hexadecanedicarboxylic acid; Octadecane-1,18-dioic acid. Grades: > 98.0 % (GC) (T). CAS No. 871-70-5. Molecular formula: C18H34O4. Mole weight: 314.5.
Octadecanedioic acid, an endogenous metabolite, is a long-chain dicarboxylic acid that has been found in serum free fatty acid profile in Reye syndrome [1]. Uses: Scientific research. Group: Natural products. CAS No. 871-70-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-W005178.
Octadecanedioic acid mono-tert-butyl ester (CAS# 843666-40-0) is used to engineer long-acting, potent exendin-4 based GLP-1 analog for microstructure-based transdermal delivery for glycemic control. Synonyms: 18-[(2-methylpropan-2-yl)oxy]-18-oxooctadecanoic acid; 18-[(2-methylpropan-2-yl)oxy]-18-oxooctadecanoic acid. CAS No. 843666-40-0. Molecular formula: C22H42O4. Mole weight: 370.6.
Octadecanoic-9,9,10,10-d4 acid
Heterocyclic Organic Compound. Alternative Names: OCTADECANOIC-9,9,10,10-D4 ACID. CAS No. 130048-57-6. Molecular formula: C18H32D4O2. Mole weight: 288.5. Purity: 99 atom % D. Catalog: ACM130048576.
Octadecanoic acid
Stearic acid is a white solid with a mild odor. Floats on water. (USCG, 1999);DryPowder; DryPowder, OtherSolid, Liquid; Liquid; OtherSolid; OtherSolid, Liquid; PelletsLargeCrystals; PelletsLargeCrystals, Liquid; PelletsLargeCrystals, WetSolid, OtherSolid; WetSolid, Liquid;Solid;Solid;WHITE CRYSTALS OR POWDER WITH CHARACTERISTIC ODOUR.;hard, white or faintly yellowish crystalline solid/tallow odour;White solid with a mild odor. Group: Solubility enhancing reagents. Alternative Names: Stearic acid. CAS No. 57-11-4. Product ID: octadecanoic acid. Molecular formula: 284.48. Mole weight: C18H36O2. CCCCCCCCCCCCCCCCCC(=O)O. InChI= 1S / C18H36O2 / c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15- 16-17-18 (19) 20 / h2-17H2, 1H3, (H, 19, 20). QIQXTHQIDYTFRH-UHFFFAOYSA-N.