A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Piroctone Related Compound B
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Pirodavir
R-77975's predecessor, R 61837, a substituted phenyl-pyridazinamine, was effective in inhibiting 80% of 100 serotypes tested (EC80) at concentrations above 32 micrograms/ml, pirodavir inhibits the same percentage of viruses at 0.064 micrograms/ml. Pirodavir is also effective in inhibiting 16 enteroviruses, with an EC80 of 1.3 micrograms/ml. Pirodavir acts at an early stage of the viral replication cycle (up to 40 min after infection) and reduces the yield of selected rhinoviruses 1,000- to 100,000-fold in a single round of replication. Adults with symptoms of < or=2 days' duration were randomly assigned to intranasal sprays of pirodavir (2 mg per treatment) or placebo six times daily for 5 days. In people with laboratory-documented rhinovirus colds (53 in the pirodavir group, 55 in the placebo group), no significant differences in the resolution of respiratory symptoms were apparent between the groups. The median duration of illness was 7 days in each group. Similarly, scores for individual symptoms found no differences in favor of pirodavir during or after treatment. Synonyms: R 77975; R-77975; R77975; R77,975; R 77,975; R-77,975; Pirodavir. Grades:>98%. CAS No. 124436-59-5. Molecular formula: C21H27N3O3. Mole weight: 369.46.
Piromelatine (Neu-P11) is a melatonin MT 1 /MT 2 receptor agonist, serotonin 5-HT 1A / 5-HT 1D agonist, and serotonin 5-HT 2B antagonist. Piromelatine (Neu-P11) possesses sleep promoting, analgesic, anti-neurodegenerative, anxiolytic and antidepressant potentials. Piromelatine (Neu-P11) also possesses pain-related P2X3, TRPV1, and Nav1.7 channel-inhibition capacities [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Neu-P11. CAS No. 946846-83-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105285.
Piromidic acid
Piromidic acid is a quinolone antibiotic to treat gram-negative bacteria infections. Uses: Quinolone antibacterial. Synonyms: 8-ethyl-5-oxo-2-pyrrolidin-1-ylpyrido[2,3-d]pyrimidine-6-carboxylic acid Acid, Piromidic Piromidic Acid. Grades: 95%. CAS No. 19562-30-2. Molecular formula: C14H16N4O3. Mole weight: 288.30.
Piromidic acid
Piromidic acid. Group: Biochemicals. Alternative Names: 8-Ethyl-5, 8-dihydro-5-oxo-2-(1-pyrrolidinyl)pyrido[2, 3-d]pyrimidine-6-carboxylic acid; 5,8-Dihydro-8-ethyl-5-oxo-2-pyrrolidinopyrido[2,3-d]pyrimidine-6-carboxylic acid; Bactramyl. Grades: Highly Purified. CAS No. 19562-30-2. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C14H16N4O3. US Biological Life Sciences.
Worldwide
Pironetin
Pironetin is a plant growth regulator produced by Streptomyces sp. NK10958. Synonyms: PA 48153C. CAS No. 151519-02-7. Molecular formula: C19H32O4. Mole weight: 324.5.
Piroxantrone
Piroxantrone is an anthrapyrazole antineoplastic antibiotic. Piroxantrone intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. Although less cardiotoxic than doxorubicin, this agent exhibits a narrow spectrum of antineoplastic activity. Synonyms: oxanthrazole; oxantrazole; Piroxantrone HCl; PD-111815; PD 111815; PD111815. CAS No. 91441-23-5. Molecular formula: C21H25N5O4. Mole weight: 411.46.
Piroxicam
Piroxicam (CP-16171) is a non-steroidal anti-inflammatory drugs, acts as a COX inhibitor, with IC 50 s of 47, 25 μM for human monocyte COX-1 and COX-2, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-16171. CAS No. 36322-90-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0253.
Piroxicam
Piroxicam is a non-selective COX inhibitor with an IC50 of 6 mM. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: CP 16171; CP16171; CP-16171. Grades: >98%. CAS No. 36322-90-4. Molecular formula: C15H13N3O4S. Mole weight: 331.35.
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C15H13N3O4S. CAS No. 36322-90-4. Prepack ID 23214960-1g. Molecular Weight 331.35. See USA prepack pricing.
Piroxicam
Non-steroidal anti-inflammatory with long half-life. Cyclooxygenase inhibitor. Clinically useful NSAID. Piroxicam may be useful for chemoprevention of solid cancers via inhibition of cyclooxygenase. Statins, which are used clinically for anti-inflammation, immunomodulation, neuroprotection, and im-provement of bone metabolism, have remarkable efficiency as individual drugs or assistant medicines that affect cell viability by inducing apoptosis.. Group: Biochemicals. Alternative Names: 4-Hydroxy-2-methyl-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboxamide 1,1-Dioxide;Artroxicam; Baxo; Bruxicam; CHF 1251; CP 16171; Caliment; Roxicam; Roxiden; Sasulen; Solocalm. Grades: Highly Purified. CAS No. 36322-90-4. Pack Sizes: 5g, 10g. Molecular Formula: C??H??N?O?S, Molecular Weight: 331.35. US Biological Life Sciences.
Worldwide
Piroxicam-b-cyclodextrin complex
Piroxicam-b-cyclodextrin complex. CAS No. 121696-62-6. Product ID: 8-04454.
Piroxicam-b-Cyclodextrin complex. CAS No. 96684-39-8. Product ID: 8-04736.
Piroxicam-β-cyclodextrin
Piroxicam-β-cyclodextrin is a non-steroidal anti-inflammatory drug with anti-inflammatory, analgesic and antipyretic properties. Synonyms: Piroxicam-beta-cyclodextrin; Chf 1194; Chf-1194; Piroxicam mixture with beta-cyclodextrin. CAS No. 96684-39-8. Molecular formula: C57H83N3O39S. Mole weight: 1466.33.
Piroxicam-d3
Piroxicam-d3. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-Hydroxy-2-(methyl-d3)-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboxamide 1,1-Dioxide;Artroxicam-d3;Baxo-d3;Bruxicam-d3;Caliment-d3;CHF 1251-d3;CP 16171-d3;Piroxicam-d3. Product Category: Heterocyclic Organic Compound. Appearance: Pale Yellow Solid. CAS No. 942047-64-5. Molecular formula: C15H10D3N3O4S. Product ID: ACM942047645. Alfa Chemistry ISO 9001:2015 Certified.
Piroxicam-d3
Non-steroidal anti-inflammatory with long half-life. Cyclooxygenase inhibitor. Clinically useful NSAID. Group: Biochemicals. Alternative Names: 4-Hydroxy-2-(methyl-d3)-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboxamide 1,1-Dioxide; Artroxicam-d3; Baxo-d3; Bruxicam-d3; CHF 1251-d3; CP 16171-d3; Caliment-d3. Grades: Highly Purified. CAS No. 942047-64-5. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Piroxicam Impurity 1
An impurity of Piroxicam which is a nonsteroidal anti-inflammatory drug. Grades: > 95%. Molecular formula: C18H19N3O4S. Mole weight: 373.43.
Piroxicam Impurity B
An impurity of Piroxicam which is an anti-inflammatory drug used for the treatment of inflammation and pain caused by rheumatoid arthritis or osteoarthritis. Synonyms: 4-Hydroxy-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboxamide 1,1-Dioxide. Grades: > 95%. CAS No. 65897-46-3. Molecular formula: C14H11N3O4S. Mole weight: 317.33.
Piroxicam Impurity C
An impurity of Piroxicam which is a nonsteroidal anti-inflammatory drug. Synonyms: 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxamide 1,1-Dioxide. Grades: > 95%. CAS No. 24683-25-8. Molecular formula: C10H10N2O4S. Mole weight: 254.27.
Piroxicam Impurity D
An impurity of Piroxicam which is used for the treatment of inflammation and pain caused by rheumatoid arthritis or osteoarthritis. Synonyms: 3-Oxo-1,2-benzoisothiazoline-2-acetic Acid Methyl Ester 1,1-Dioxide; Saccharin N-(2-Acetic Acid Methyl Ester); NSC 49216. Grades: > 95%. CAS No. 6639-62-9. Molecular formula: C10H9NO5S. Mole weight: 255.25.
Piroxicam impurity F
An impurity of Piroxicam which is a non-selective COX inhibitor with an IC50 of 6 mM. Synonyms: 3-Oxo-1,2-benzisothiazole-2(3H)-acetic Acid 1-Methylethyl Ester 1,1-Dioxide; 1-Methylethyl (1,1-Dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl)acetate; Isopropyl 3-Oxo-1,2-benzisothiazole-2(3H)acetate 1,1-Dioxide. Grades: > 95%. CAS No. 76508-37-7. Molecular formula: C12H13NO5S. Mole weight: 283.31.
Piroxicam Impurity G
An impurity of Piroxicam which is an anti-inflammatory drug used for the treatment of inflammation and pain caused by rheumatoid arthritis or osteoarthritis. Synonyms: 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylic Acid Methyl Ester 1,1-Dioxide; Methyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide. Grades: > 95%. CAS No. 35511-14-9. Molecular formula: C10H9NO5S. Mole weight: 255.25.
Piroxicam Impurity I
An impurity of Piroxicam which is used for the treatment of inflammation and pain caused by rheumatoid arthritis or osteoarthritis. Synonyms: 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylic Acid 1-Methylethyl Ester 1,1-Dioxide; 1-Methylethyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide; NSC 642708. Grades: > 95%. CAS No. 76508-35-5. Molecular formula: C12H13NO5S. Mole weight: 283.31.
Piroxicam Impurity J
Methyl 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide is the Piroxicam Impurity J. It Is also an impurity found in Meloxicam. Synonyms: Methyl 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide; 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic Acid Methyl Ester 1,1-Dioxide; Piroxicam Impurity J. Grades: > 95%. CAS No. 35511-15-0. Molecular formula: C11H11NO5S. Mole weight: 269.27.
Piroxicam impurity L
Isopropyl 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide is a Piroxicam Impurity L. It is also an impurity found in meloxicam. Synonyms: Isopropyl 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide; 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic Acid 1-Methylethyl Ester 1,1-Dioxide; 1-Methylethyl 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide; NSC 64. Grades: > 95%. CAS No. 118854-48-1. Molecular formula: C13H15NO5S. Mole weight: 297.33.
Piroxicam-(methyl-d3)
analytical standard. Group: Opiates / synthetic analgesic drug standards.
Piroxicam N-β-D-Glucuronide
Piroxicam N-β-D-glucuronide is a derivative of Piroxicam. Piroxicam is an acidic, as well as an anti-inflammatory agent that is used for the treatment of rheumatoid arthritis. It also has potential ulcerogenic effects. Molecular formula: C21H22N3O10S. Mole weight: 508.48.
Piroxicam N-β-D-Glucuronide 6'-Methyl Ester
Piroxicam N-β-D-Glucuronide 6'-Methyl Ester is a derivative of Piroxicam. Piroxicam is an acidic, anti-inflammatory agent which is used for the treatment of rheumatoid arthritis. It also has potential ulcerogenic effects. Molecular formula: C22H24N3O10S. Mole weight: 522.5.
Piroxicam N-β-D-Glucuronide 6'-Methyl Ester 2',3',4'-Triacetate is a derivative of Piroxicam. Piroxicam is an acidic, anti-inflammatory agent which is used for the treatment of rheumatoid arthritis. It also has potential ulcerogenic effects. Molecular formula: C28H30N3O13S. Mole weight: 648.61.
Pirozadil is a drug used to treat type IIa hyperlipidemia. Synonyms: Pemix. Grades: 98%. CAS No. 54110-25-7. Molecular formula: C27H29NO10. Mole weight: 527.5.
Pirozadil
Pirozadil. Group: Biochemicals. Alternative Names: 3,4,5-Trimethoxybenzoic Acid 1, 1'-[2, 6-Pyridinediylbis (methylene)] Ester; 722D; Pemix; Pirozadil. Grades: Highly Purified. CAS No. 54110-25-7. Pack Sizes: 250mg. Molecular Formula: C27H29NO10, Molecular Weight: 527.52. US Biological Life Sciences.
Worldwide
Pirtobrutinib
Pirtobrutinib is a Bruton's tyrosine kinase (BTK) inhibitor and antineoplastic agent. Synonyms: BTK inhibitor 16; LY 3527727; LOXO-305; (S)-5-amino-3-(4-((5-fluoro-2-methoxybenzamido)methyl)phenyl)-1-(1,1,1-trifluoropropan-2-yl)-1H-pyrazole-4-carboxamide. Grades: >98%. CAS No. 2101700-15-4. Molecular formula: C22H21F4N5O3. Mole weight: 479.4.
Pirtobrutinib
Pirtobrutinib (LOXO-305), a highly selective and non-covalent next generation BTK inhibitor, inhibits diverse BTK C481 substitution mutations. Pirtobrutinib causes regression of BTK-dependent lymphoma tumors in mouse xenograft models. Pirtobrutinib is also more than 300-fold selective for BTK versus 370 other kinases tested and shows no significant inhibition of non-kinase off-targets at 1 μM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LOXO-305. CAS No. 2101700-15-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131328.
Pirtobrutinib
Pirtobrutinib, also known as LOXO-305 and LY 3527727, is a Bruton's tyrosine kinase (BTK) inhibitor and antineoplastic agent. Pirtobrutinib showed promising initial efficacy in pts with pretreated Richter transformation with extremely poor prognosis, including in patients who had received prior chemoimmunotherapy and covalent BTK inhibitors. Pirtobrutinib is a highly selective and potent non-covalent BTK inhibitor (BTKi) with high oral bioavailability and a long half-life, resulting in robust BTK target coverage even in high-grade malignancies with high BTK protein turnover. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Pirtobrutinib; LOXO-305; LOXO 305; LOXO305; LY 3527727; LY-3527727; LY3527727. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2101700-15-4. Molecular formula: C22H21F4N5O3. Mole weight: 479.44. Purity: >98%. IUPACName: (S)-5-amino-3-(4-((5-fluoro-2-methoxybenzamido)methyl)phenyl)-1-(1,1,1-trifluoropropan-2-yl)-1H-pyrazole-4-carboxamide. Canonical SMILES: O=C(C1=C(N)N([C@@H](C)C(F)(F)F)N=C1C2=CC=C(CNC(C3=CC(F)=CC=C3OC)=O)C=C2)N. Product ID: ACM2101700154. Alfa Chemistry ISO 9001:2015 Certified.
Pis1
Pis1 is an antimicrobial peptide found in Gadus morhua, and has antibacterial activity. Synonyms: Phe-Ile-His-His-Ile-Ile-Gly-Trp-Ile-Ser-His-Gly-Val-Arg-Ala-Ile-His-Arg-Ala-Ile-His-Gly. Grades: ≥97%. Molecular formula: C118H179N39O24. Mole weight: 2527.98.
Pis2
Pis2 is an antimicrobial peptide found in Gadus morhua, and has anti-gram-negative bacteria (Y. ruckeric NCIMB 2196 and P. immobilisc NCIMB 308 (MIC 2.5-5 uM)) and antiparasitic activity. Synonyms: Phe-Leu-His-His-Ile-Val-Gly-Leu-Ile-His-His-Gly-Leu-Ser-Leu-Phe-Gly-Asp-Arg-Ala-Asp. Grades: ≥97%. Molecular formula: C109H164N32O27. Mole weight: 2354.71.
Piscidin 4
Piscidin 4 is an antimicrobial peptide found in hybrid striped bass (Morone chrysops female x M. saxatilis male), and has potent and broad-spectrum antibacterial activity. Grades: >98%.
Piscidin-like antimicrobial peptide precursor
Piscidin-like antimicrobial peptide precursor is an antimicrobial peptide isolated from Epinephelus bleekeri. Synonyms: Arg-Cys-Ile-Ala-Leu-Phe-Phe-Val-Leu-Ser-Leu-Val-Val-Leu-Met-Ala-Glu-Pro-Gly-Glu-Gly-Phe-Phe-Phe-His-Ile-Ile-Lys-Gly-Leu-Phe-His-Ala-Gly-Lys-Met-Ile-His-Gly-Leu-Ile.
Piscidin-like peptide
Piscidin-like peptide is an antibacterial peptide isolated from Epinephelus fuscoguttatus. Synonyms: Arg-Cys-Ile-Ala-Leu-Phe-Leu-Val-Leu-Ser-Leu-Val-Ala-Leu-Met-Ala-Glu-Pro-Gly-Glu-Gly-Phe-Ile-Phe-His-Ile-Ile-Lys-Gly-Leu-Val-His-Ala-Gly-Lys-Met-Ile-His-Gly-Leu-Val.
p-(Isopentyl)benzaldehyde
p-(Isopentyl)benzaldehyde. Uses: Designed for use in research and industrial production. Additional or Alternative Names: p-(Isopentyl)benzaldehyde, EINECS 283-579-4, CID3020040, 84682-18-8. Product Category: Heterocyclic Organic Compound. CAS No. 84682-18-8. Molecular formula: C12H16O. Mole weight: 176.254840 [g/mol]. Purity: 0.96. IUPACName: 4-(3-methylbutyl)benzaldehyde. Canonical SMILES: CC(C)CCC1=CC=C(C=C1)C=O. Density: 0.958g/cm³. ECNumber: 283-579-4. Product ID: ACM84682188. Alfa Chemistry ISO 9001:2015 Certified.
p-Isopropoxydiphenylamine
p-Isopropoxydiphenylamine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-(1-methylethoxy)-n-phenyl-benzenamin;4-(isopropyloxy)diphenylamine;4-isopropoxy-diphenylamin;4-isopropoxydiphenylamine;4-isopropyloxydiphenylamine;agerite150;ageriteiso;isopropoxyphenyl-4-aniline. Product Category: Heterocyclic Organic Compound. Appearance: Dark gray flakes or flaky black solid. CAS No. 101-73-5. Molecular formula: C15H17NO. Mole weight: 227.3. Product ID: ACM101735. Alfa Chemistry ISO 9001:2015 Certified.
p-Isopropylbenzyl formate
p-Isopropylbenzyl formate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 67634-21-3, p-Isopropylbenzyl formate, AC1L2YRN, 4-(propan-2-yl)benzyl formate, EINECS 266-826-0, (4-propan-2-ylphenyl)methyl formate, Benzenemethanol, 4-(1-methylethyl)-, formate, Benzenemethanol, 4-(1-methylethyl)-, 1-formate. Product Category: Heterocyclic Organic Compound. CAS No. 67634-21-3. Molecular formula: C11H14O2. Mole weight: 178.227660 [g/mol]. Purity: 0.96. IUPACName: (4-propan-2-ylphenyl)methyl formate. Canonical SMILES: CC(C)C1=CC=C(C=C1)COC=O. Density: 1.012g/cm³. ECNumber: 266-826-0. Product ID: ACM67634213. Alfa Chemistry ISO 9001:2015 Certified.
PIT
PIT. Group: Biochemicals. Grades: Purified. CAS No. 56583-49-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PIT
PIT (2,2'-Pyridylisatogen tosylate) is a selective and non-competitive antagonist of P2Y1 receptor with an IC 50 value of 0.14 μM for human P2Y1 receptor. PIT antagonizes P2Y1 receptor signaling without affecting nucleotide binding. PIT is an irreversible antagonist of responses to ATP at metabotropic purinoceptors (of the P2Y family) in some smooth muscles. PIT can be used for the research of chronic bronchitis and asthma [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2,2'-Pyridylisatogen tosylate. CAS No. 56583-49-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108662.
PIT
PIT selectively and non-competitively blocked P2Y1 receptor signaling without affecting nucleotide binding. PIT had no significant effect on agonist activation of other P2Y receptors, including P2Y2, P2Y4, P2Y6, P2Y11 and P2Y12 receptors. Synonyms: 2-(2-Pyridinyl)-(3H)-indol-3-one-1-oxide 4-methylbenzenesulfonate; 2,2'-Pyridylisatogen tosylate. Grades: ≥99% by HPLC. CAS No. 56583-49-4. Molecular formula: C13H8N2O2.C7H8O3S. Mole weight: 396.42.
PIT 1. Group: Biochemicals. Grades: Purified. CAS No. 53501-41-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PIT 1
PIT 1 is an apoptosis inducing selective PIP3 antagonist which has been shown to inhibit the binding of PIP3 to the pleckstrin homology (PH) domain of Akt (IC50 = 31.03 μM). PIT 1 inhibits cancer cell survival and induces apoptosis by inhibition of PIP3-dependent PI 3-kinase/Akt signaling, and exhibits antitumor activity in vivo. Synonyms: Pit-1; Pit 1; Pit1. N-[[ (3-Chloro-2-hydroxy-5-nitrophenyl) amino]thioxomethyl]benzamide. Grades: ≥99% by HPLC. CAS No. 53501-41-0. Molecular formula: C14H10ClN3O4S. Mole weight: 351.76.
PIT-1
PIT-1 is a selective PIP3 (phosphatidylinositol 3,4,5-trisphosphate) antagonist. PIT-1 inhibits cancer cell survival and induces apoptosis by inhibition of PIP3 dependent PI3K / Akt signaling. PIT-1 exhibits antitumor activity in vivo [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 53501-41-0. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103224.
Pitavastatin
Pitavastatin (NK-104) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin inhibits cholesterol synthesis from acetic acid with an IC 50 of 5.8 nM in HepG2 cells. Pitavastatin is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects [1] [2] [3] [8]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NK-104. CAS No. 147511-69-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B0144A.
Pitavastatin
Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. IC50: HepG2=5.8 nM. Synonyms: Zypitamag; (3R,5S,6E)-7-(2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoic acid; (3R,5S)-3,5-Dihydroxy-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-6-heptenoic acid; Itavastatin; Livalo; NK 104; itavastatinn; NK-104; NK104; P 872441; P-872441; P872441. Grades: > 98%. CAS No. 147511-69-1. Molecular formula: C25H24FNO4. Mole weight: 421.46.
Pitavastatin
Pitavastatin. Uses: Designed for use in research and industrial production. CAS No. 147526-32-7. Molecular formula: C25H24FNO4. Mole weight: 421.46. Purity: 0.98. Product ID: ACM147526327. Alfa Chemistry ISO 9001:2015 Certified.
Pitavastatin 1-Phenylethylamide
Pitavastatin 1-Phenylethylamide is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Pitavastatin Impurity. Molecular formula: C33H33FN2O3. Mole weight: 524.62.
Pitavastatin 3-Ether Glucuronide
Pitavastatin 3-Ether Glucuronide is one of pitavastatin metabolites. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: β-D-Glucopyranosiduronic acid, (1R,3S,4E)-1-(carboxymethyl)-5-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3-hydroxy-4-penten-1-yl; (1R,3S,4E)-1-(Carboxymethyl)-5-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3-hydroxy-4-penten-1-yl β-D-Glucopyranosiduronic Acid; (2R,4S,5E)-1-Carboxy-6-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-4-hydroxy-5-hexen-2-yl β-D-glucopyranosiduronic acid. Grades: ≥95%. CAS No. 224320-11-0. Molecular formula: C31H32FNO10. Mole weight: 597.58.
Pitavastatin 3-Ether Glucuronide
Pitavastatin 3-Ether Glucuronide. Group: Biochemicals. Alternative Names: (1R,3S,4E)-1-(Carboxymethyl)-5-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3-hydroxy-4-penten-1-yl β-D-Glucopyranosiduronic Acid. Grades: Highly Purified. CAS No. 224320-11-0. Pack Sizes: 1mg. Molecular Formula: C31H32FNO10, Molecular Weight: 597.58. US Biological Life Sciences.
Worldwide
Pitavastatin 3-O-Glucuronide
A metabolite of Pitavastatin which is a Hydroxymethylglutaryl-CoA reductase inhibitor. Grades: > 95%. Molecular formula: C31H31FNO10. Mole weight: 596.58.
Pitavastatin 3-Oxo Acid
A metabolite of Pitavastatin which causes atherosclerosis regression in humans with subclinical carotid atherosclerosis. Grades: > 95%. Molecular formula: C25H22FNO4. Mole weight: 419.46.
Pitavastatin 3-Oxo Ethyl Ester
A metabolite of Pitavastatin which lowers both total cholesterol and low density lipoprotein cholesterol in animals and humans. Synonyms: (E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoic Acid Ethyl Ester. Grades: > 95%. CAS No. 148901-69-3. Molecular formula: C27H26FNO4. Mole weight: 447.51.
Pitavastatin 3-Oxo Sodium
A metabolite of Pitavastatin which is a chemically synthesized statin used for hypercholesterolaemia (elevated cholesterol) and for the prevention of cardiovascular disease. Synonyms: 3-Oxo Pitavastatin Sodium; Sodium (5S, 6E)-7-[2-cyclopropyl-4-(4-flurophenyl)-3- quinolinyl]-5-hydroxy-3-oxo-6-heptenoate. Grades: > 95%. Molecular formula: C25H21FNO4.Na. Mole weight: 441.44.
Pitavastatin 3S, 5R-Isomer Sodium
A metabolite of Pitavastatin which is a potent HMG-CoA reductase inhibitor. Grades: > 95%. Molecular formula: C25H23FNO4.Na. Mole weight: 443.45.
Pitavastatin 3S, 5S-Isomer Sodium
A metabolite of Pitavastatin which is a member of the blood cholesterol lowering medication class of statins. Grades: > 95%. Molecular formula: C25H23FNO4.Na. Mole weight: 443.45.
Pitavastatin 5-Oxo Impurity
An impurity of Pitavastatin which induces plaque regression and elevates HDL-cholesterol levels. Synonyms: (3R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3-hydroxy-5-oxo-6-heptenoic Acid. Grades: > 95%. CAS No. 222306-15-2. Molecular formula: C25H22FNO4. Mole weight: 419.46.
Pitavastatin 5-Oxo Impurity Calcium Salt
An impurity in the synthesis of Pitavastatin, a HMG-CoA reductase inhibitor that lowers LDL cholesterol and triglycerides and increase HDL cholesterol in your blood. Synonyms: (3R,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3-hydroxy-5-oxo-6-heptenoic acid calcium salt (2:1). CAS No. 2180095-22-9. Molecular formula: C50H42CaF2N2O8. Mole weight: 876.9.
Pitavastatin (5R)-Oxo Impurity
An impurity of Pitavastatin which inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Grades: > 95%. Molecular formula: C26H24FNO4. Mole weight: 433.48.