A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
p-Nitrophenyl β-D-Cellotrioside Decaacetate is an intermediate in the synthesis of p-Nitrophenyl β-D-Cellotrioside. Molecular formula: C44H55NO28. Mole weight: 1045.9.
A selective formylating agent for one of two amino groups in such basic amino acids as ornithine or lysine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25g. US Biological Life Sciences.
Worldwide
p-Nitrophenyl Heptyl Ether
Clear liquid. Synonyms: p-Heptyloxynitrobenzene. CAS No. 13565-36-1. Pack Sizes: 5g. Product ID: FR-1109. B.P. 165-166/0.5 mm. Mole weight: 237.3.
Substrate for the colorimetric assay of lysozyme. Uses: Substrate for the colorimetric assay of lysozyme. Synonyms: 4-Nitrophenyl O-2-(Acetylamino)-2-deoxy-β-D-glucopyranosyl-(14)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(14)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(14)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(14)-2-(acetylamino)-2-deoxy-β-D-glucopyranoside; p-Nitrophenyl β-D-N,N',N'',N''',N''''-Pentaacetylhitopentaoside. Grades: 95%. CAS No. 114882-45-0. Molecular formula: C46H70N6O28. Mole weight: 1155.07.
p-Nitrophenyl Pentyl Ether
Liquid. Synonyms: p-Pentyloxynitrobenzene. CAS No. 63469-11-4. Pack Sizes: 5g. Product ID: FR-1220. B.P. 192-195/16 mm. Mole weight: 209.25.
Frinton Laboratories
P-Nitrophenyl phosphate disodium salt
PNPP, Disodium Salt is a colorimetric alkaline phosphatase soluble substrate, p-Nitrophenyl Phosphate (pNPP) is the substrate of choice for use with alkaline phosphatase in Enzyme Linked Immunosorbant Assay (ELISA) procedures. Synonyms: PNPP; Disodium 4-nitrophenylphosphate; sodium 4-nitrophenyl phosphate; Phosphoric acid, mono(4-nitrophenyl) ester, disodium salt; 4-Nitrophenyl phosphate disodium salt; Phosphoric Acid 4-Nitrophenyl Ester Disodium Salt; Disodium p-Nitrophenyl Phosphate; p-NPP Disodium Salt; Mono(p-nitrophenyl) Ester Phosphoric Acid Disodium Salt. Grades: ≥98% by HPLC. CAS No. 4264-83-9. Molecular formula: C6H4NNa2O6P. Mole weight: 263.05.
p-Nitrophenylpyruvic acid
Red powder, 98%. CAS No. 38335-24-9. Pack Sizes: 2g, 5g. Product ID: FR-2150. M.P. 191-193. Mole weight: 209.16.
p-nitro-Pifithrin-α, a cell-permeable analog of pifithrin-α, is a potent p53 inhibitor. p-nitro-Pifithrin-α suppresses p53-mediated TGF-β1 expression in HK-2 cells. p-nitro-Pifithrin-α inhibits the activation of caspase-3 by Zika virus (ZIKV) strains. p-nitro-Pifithrin-α attenuates steatosis and liver injury in mice fed a high-fat diet [4]. non-alcoholic fatty liver disease [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 389850-21-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-130437.
p-nitro-Pifithrin-α
p-nitro-Pifithrin-α is a cell-permeable p53 inhibitor. It blocks p53-mediated expression of p21/WAF1 and apoptosis in cortical neurons ten-fold more potently than pifithrin-&alpha. It also suppresses p53-mediated TGF-β1 expression in human proximal tubular cells and attenuates steatosis and liver injury in mice fed a high-fat diet. Synonyms: p-nitro-PFT-α; 2-(2-imino-4,5,6,7-tetrahydro-1,3-benzothiazol-3-yl)-1-(4-nitrophenyl)ethanone hydrobromide. Grades: ≥95%. CAS No. 389850-21-9. Molecular formula: C15H15N3O3S·HBr. Mole weight: 398.3.
p-Nitropropionanilide
p-Nitropropionanilide. Group: Biochemicals. Grades: Highly Purified. CAS No. 4850-93-5. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C9H10N2O3. US Biological Life Sciences.
Worldwide
p-Nitroso-m-cresol
p-Nitroso-m-cresol. Group: Biochemicals. Alternative Names: 3-Methyl-4-nitrosophenol; 4-Nitroso-3-methylphenol; 4-Nitroso-m-cresol; NSC 21470; NSC 677513. Grades: Highly Purified. CAS No. 615-01-0. Pack Sizes: 250mg. Molecular Formula: C7H7NO2, Molecular Weight: 137.139999999999. US Biological Life Sciences.
An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: 4-(4-HYDROXYBENZYLIDENE) FLUORO ANILINE; 4-(((4-FLUOROPHENYL)IMINO)METHYL)PHENOL; 2-(4 ' -Hydrophenyl)-4-fluorobenyl imine; alpha-4-Fluorophenylimino-p-cresol; (E)-4-((4-Fluorophenylimino)methyl)phenol; 4-fluoro-N-(hydroxyphenyl)methylene-benzenamine; E2:4{[(4. Grades: 98%. CAS No. 3382-63-6. Molecular formula: C13H10FNO. Mole weight: 215.22.
PNP palmitate
5g Pack Size. Group: Analytical Reagents, Biochemicals, Stains & Indicators. Formula: C22H35NO4. CAS No. 1492-30-4. Prepack ID 90020885-5g. Molecular Weight 377.52. See USA prepack pricing.
PNPP disodium
PNPP (Para-nitrophenyl phosphate) disodium is a non-proteinaceous chromogenic substrate for alkaline and acid phosphatases used in ELISA and conventional spectrophotometric assays. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Para-nitrophenyl phosphate disodium. CAS No. 4264-83-9. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-15928.
PNRI-299
PNRI-299 is a selective AP-1 transcription inhibitor without affecting NF-kappaB transcription or thioredoxin. Synonyms: PNRI-299; PNRI299; PNRI 299. Grades: >98%. CAS No. 550368-41-7. Molecular formula: C21H15N5O4. Mole weight: 401.37.
PNT6555
PNT6555 is a fibroblast activation protein-α ( FAP ) inhibitor. PNT6555 has antitumor activity. PNT6555 can be used for imaging of FAP -positive tumors [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2715113-34-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-161074.
PNU-101603
Orally administered sutezolid is rapidly oxidized in vivo to an active sulfoxide metabolite (PNU-101603), which then undergoes renal excretion. Synonyms: Sutetolid sulfoxide; Acetamide, N-[[(5S)-3-[3-fluoro-4-(1-oxido-4-thiomorpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-. CAS No. 168828-60-2. Molecular formula: C16H20FN3O4S. Mole weight: 369.41.
PNU-104489
PNU-104489, a sulfonamidoindol derivative, has been found to be a HIV-1 specific inhibitor and was proved to exhibit activity against BHA-P-resistant HIV-1MF harboring the Pro-236->Leu RT. Synonyms: U 104489; U-104489; U104489; PNU-104489; PNU104489; PNU 104489; Alkylamino-piperidine analog; 1-((5-Methanesulfonamidoindol-2-yl)carbonyl)-4-(N-ethyl-N-(3-((1,1-dimethylethyl)amino)-2-pyridinyl)amino)piperidine. Grades: 98%. CAS No. 177577-60-5. Molecular formula: C26H36N6O3S. Mole weight: 512.67.
PNU 109291
PNU 109291. Group: Biochemicals. Grades: Purified. CAS No. 187665-60-7. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
PNU 120596
PNU 120596. Group: Biochemicals. Grades: Purified. CAS No. 501925-31-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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PNU-120596
PNU-120596 (NSC 216666) is a potent and selective α7 nAChR positive allosteric modulator (PMA) with an EC 50 of 216 nM. PNU-120596 is inactive against α4β2, α3β4, and α9α10 nAChRs. PNU-120596 has the potential for psychiatric and neurological disorders research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC 216666. CAS No. 501925-31-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12152.
PNU-120596
PNU-120596 is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM. Synonyms: PNU-120596; PNU 120596; PNU120596; NSC 216666; NSC-216666; NSC216666. Grades: >98%. CAS No. 501925-31-1. Molecular formula: C13H14ClN3O4. Mole weight: 311.72.
A urea derivative that acts as a potent, selective, and reversible positive allosteric modulator for the a7 subtype of neural nicotinic acetylcholine receptors (EC50 = 216nM), with no significant effect on a4B2, a3B4 and a9a10 receptors. Specifically increase a-7 nAChR-mediated channel currents and channel mean open time in cultured neurons (~1mM). However, it does neither affect ion selectivity nor unitary conductance. Shown to cross the blood-brain barrier. Causes conformational changes in the ligand binding domain of a7 nicotinic receptors that partially overlap with those caused by acetylcholine. Causes changes in cysteine accessibility at the inner beta sheet, transition zone, and agonist binding site. Also reported to potentiate agonist-evoked GABAergic postsynaptic inward currents in somatodendritic membrane of hippocampal interneurons. Group: Biochemicals. Grades: Highly Purified. CAS No. 501925-31-1. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
PNU 142586 Sodium Salt
PNU 142586 Sodium Salt is an inactive metabolite of Linezolid. Synonyms: N-[4-[(5S)-5-[(Acetylamino)methyl]-2-oxo-3-oxazolidinyl]-2-fluorophenyl]-N-(2-hydroxyethyl)glycine Sodium Salt. Grades: > 95%. Molecular formula: C16H19FN3O6Na. Mole weight: 391.33.
PNU 142633
PNU 142633 is a selective, high affinity 5-HT1D receptor antagonist (Ki values are 6 and > 18000 nM at human 5-HT1D and 5-HT1B receptors respectively). It is an experimental drug candidate for the treatment of migraine. Synonyms: (1S)-1-[2-[4-[4-(Aminocarbonyl)phenyl]-1-piperazinyl]ethyl]-3,4-dihydro-N-methyl-1H-2-benzopyran-6-carboxamide; PNU-142633; PNU 142633; PNU142633. Grades: ≥98% by HPLC. CAS No. 187665-65-2. Molecular formula: C24H30N4O3. Mole weight: 422.53.
PNU 142633
PNU 142633. Group: Biochemicals. Grades: Purified. CAS No. 187665-65-2. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
PNU-142633
PNU-142633 is a high affinity, selective and orally active 5-HT 1D receptor agonist with K i s of 6 nM and > 18 000 nM for human 5-HT 1D receptor and human 5-HT 1B receptor, respectively. PNU-142633 has anti-migraine efficacy [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 187665-65-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-103131.
PNU177836
PNU177836 is an esteemed inhibitor, finding extensive utilization in the research of maladies, encompassing cancer, neurodegenerative disorders as well as ischemic heart diseases. Synonyms: PNU177836; 5-(2-{2-[(TERT-BUTOXY-HYDROXY-METHYL)-AMINO]-1-HYDROXY-3-PHENYL-PROPYLAMINO}-3-HYDROXY-3-PENTYLAMINO-PROPYL)-2-CARBOXYMETHOXY-BENZOIC ACID; DB02977; Q27465943; 5-[(2S,3R)-2-{[(1S,2S)-2-{[(S)-tert-butoxy(hydroxy)methyl]amino}-1-hydroxy-3-phenylpropyl]amino}-3-hydroxy-3-(pentylamino)propyl]-2-(carboxymethoxy)benzoic acid. Molecular formula: C31H47N3O9. Mole weight: 605.72.
PNU 177864
PNU 177864, a trifluromethoxy-phenylsulphonylamine, is a highly selective dopamine D3 receptor antagonist, which induces phospholipidosis and exhibits antischizophrenic activity in vivo. Synonyms: PNU 177864 hydrochloride; PNU177864 hydrochloride; PNU-177864 hydrochloride; N-[4-[2-(Propylamino)ethyl)phenyl]-4-(trifluoromethoxy)-benzenesulfonamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 250266-51-4. Molecular formula: C18H21F3N2O3S. Mole weight: 402.4.
PNU 177864 hydrochloride
PNU 177864 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 250266-51-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PNU 177864 hydrochloride
PNU 177864 is a selective dopamine D3 receptor antagonist with antischizophrenic activity. Synonyms: N-[4-[2-(Propylamino)ethyl)phenyl]-4-(trifluoromethoxy)-benzenesulfonamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 1783978-03-9. Molecular formula: C18H21F3N2O3S·HCl. Mole weight: 438.89.
PNU 22394 hydrochloride
PNU 22394 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 15923-42-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PNU 22394 hydrochloride
PNU 22394 is virtually a full agonist at 5-HT2C receptors (87% of 5-HT), but a partial agonist at 5-HT2A (65% of 5-HT), and 5-HT2B (<15% of 5-HT) receptors. It is non-selective between 5-HT2 receptor subtypes (Ki= 18, 18 and 66 nM for human recombinant 5-HT2C, 5-HT2A and 5-HT2B receptors respectively). Synonyms: PNU22394 hydrochloride; PNU-22394 hydrochloride; 1,2,3,4,5,6-Hexahydro-6-methyl-azepino[4,5-b]indole hydrochloride; Azepino[4,5-b]indole, 1,2,3,4,5,6-hexahydro-6-methyl-, monohydrochloride; PNU 186053A; Azepino[4,5-b]indole, 1,2,3,4,5,6-hexahydro-6-methyl-, hydrochloride (1:1). Grades: ≥99% by HPLC. CAS No. 15923-42-9. Molecular formula: C13H16N2.HCl. Mole weight: 236.74.
PNU-22394 hydrochloride
PNU-22394 hydrochloride is an agonist for 5-HT , with K i of 6.1 and 10 nM, for 5-HT 2C and 5-HT 2A , respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 15923-42-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-103145.
PNU 282987
PNU 282987. Group: Biochemicals. Grades: Purified. CAS No. 123464-89-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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PNU 282987
PNU 282987 is a potent and selective agonist of α7-containing neuronal nicotinic acetylcholine receptors (nAChRs). It exhibits nootropic effects, suggesting its potential use in the treatment of schizophrenia. Synonyms: N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-4-chlorobenzamide. Grades: ≥98%. CAS No. 711085-63-1. Molecular formula: C14H17ClN2O. Mole weight: 264.8.
PNU-282987
PNU-282987 is a potent α7 nicotinic acetylcholine receptor (nAChR) agonist with an EC 50 of 154 nM. PNU-282987 is also a functional antagonist of the 5-HT 3 receptor with an IC 50 of 4541 nM. PNU-282987 can be used for the research of central and peripheral nervous systems [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 123464-89-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12560A.
PNU-282987 hydrochloride
PNU-282987 is a highly selective α7 nAChR agonist (Ki = 26 nM) displaying negligible blockade of α1β1γδ and α3β4 nAChRs (IC50 ≥ 60 μM). Found to be inactive against a panel of 32 receptors at 1 μM, except 5-HT3 receptors (Ki = 930 nM). Synonyms: PNU-282987; PNU 282987; PNU282987; Benzamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-. Grades: >98%. CAS No. 123464-89-1. Molecular formula: C14H18Cl2N2O. Mole weight: 301.21.
A potent agonist highly selective for alpha7 nAChRs (Ki = 26nM). Used in investigating the roles of alpha7 nAChRs in sensory gating, learning and memory, cognitive functions, and treatment of Schizophrenia. Group: Biochemicals. Grades: Highly Purified. CAS No. 123464-89-1. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
PNU 37883 hydrochloride
PNU 37883 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 57568-80-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PNU 37883 hydrochloride
PNU 37883 is a potent, euglycemic vascular K-ATP blocker that also exerts a K+-sparing diuresis at higher doses. It selectively inhibits Kir6 currents in isolated mesenteric artery smooth muscle cells (Kd = 65 nM) but not in cardiac or skeletal myocytes. PNU 37883 is useful biological tool in distinguishing between Kir6.1 and Kir6.2 chimeric protein functions as well as the different sulfonylurea-sensitive K+ channel subtypes. Uses: Diuretics. Synonyms: U 37883A; U37883A; U-37883A; PNU 37883; PNU37883; PNU-37883; N-Cyclohexyl-N'-tricyclo[3.3.1.13,7]dec-1-yl-4-morpholinecarboximidamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 57568-80-6. Molecular formula: C21H35N3O.HCl. Mole weight: 381.98.
PNU 74654
PNU 74654. Group: Biochemicals. Grades: Purified. CAS No. 113906-27-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PNU 74654
PNU 74654 inhibits the Wnt-β catenin pathway by blocking the interaction between β-catenin and TCF (T cell factor). Treatment of human adrenocortical cell lines with PNU 74654 significantly reduced expression of several Tcf/β-catenin target genes. Synonyms: PNU 74654; PNU-74654; PNU74654; 2-Phenoxybenzoic acid-[(5-methyl-2-furanyl)methylene]hydrazide. Grades: ≥99% by HPLC. CAS No. 113906-27-7. Molecular formula: C19H16N2O3. Mole weight: 320.34.
PNU-74654
PNU-74654 is an inhibitor of Wnt/β-catenin pathway with an IC 50 of 129.8 μM in NCI-H295 cell. Uses: Scientific research. Group: Signaling pathways. CAS No. 113906-27-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-101130.
PNU 96415E
PNU 96415E, chemically unrelated to clozapine, exhibits high affinity for dopamine D4 and serotonergic 5-HT2A receptors and relatively weak affinity at D2 receptors (Ki= 3.0, 5.8, 134, 181, 199, 240, 411 and > 678 nM for D4, 5-HT2A, 5-HT1A, α1, D2, D3, D1, α2 and muscarinic receptors respectively). PNU-96415E has a profile of behavioral effects in rodents very similar to that of clozapine, including complete discriminative stimulus generalization. Synonyms: PNU 96415E; PNU96415E; PNU-96415E; 1-[2-(3,4-Dihydro-1H-2-benzopyran-1-yl)ethyl]-4-(4-fluorophenyl)piperazine dihydrochloride. Grades: ≥98% by HPLC. CAS No. 170856-41-4. Molecular formula: C21H25FN2O.2HCl. Mole weight: 413.36.
PNU 96415E
PNU 96415E. Group: Biochemicals. Grades: Purified. CAS No. 170856-41-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Pnz-onb
Heterocyclic Organic Compound. CAS No. 1154758-31-2. Purity: 0.96. Catalog: ACM1154758312.
PNZ-ONb
PNZ-ONb. Group: Biochemicals. Grades: Highly Purified. CAS No. 193269-82-8. Pack Sizes: 100mg, 250mg, 500mg, 1g. US Biological Life Sciences.