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| Product | Description | |
|---|---|---|
| Plinabulin | Plinabulin (NPI-2358) is a vascular disrupting agen ( VDA ) against tubulin-depolymerizing with an IC 50 of 9.8 nM against HT-29 cells [1]. Plinabulin binds the colchicine binding site of β-tubulin preventing polymerization and has potent inhibitory to tumor cells [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NPI-2358. CAS No. 714272-27-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14444. |  |
| Plinabulin | Plinabulin is a vascular disrupting agent (VDA) against tubulin-depolymerizing with IC50 value of 9.8~18 nM in tumor cells under the development of Nereus Pharmaceuticals. It can bind to the colchicine binding site of b-tubulin preventing polymerization and disrupting the cytoplasmic microtubule network. In Sep 2016, BeyondSpring Pharmaceuticals planed a phase II/III trial for Neutropenia. Phase I clinical trials for Solid tumours and Phase III clinical trials for Non-small cell lung cancer are on-going. Uses: Non-small cell lung cancer; neutropenia;solid tumours. Synonyms: NPI 2358; NPI2358; NPI-2358; Plinabulin; UNII-986FY7F8XR; (3Z,6Z)-3-benzylidene-6-[(5-tert-butyl-1H-imidazol-4-yl)methylidene]piperazine-2,5-dione. Grades: 98%. CAS No. 714272-27-2. Molecular formula: C19H20N4O2. Mole weight: 339.39. |  |
| Plitidepsin | Plitidepsin is a cyclic depsipeptide isolated from the marine tunicate Aplidium albicans. Plitidepsin shows potent anticancer activity against a large variety of cultured human cancer cells, inducing apoptosis by triggering mitochondrial cytochrome c release, initiating the Fas/DC95, JNK pathway and activating caspase 3 activation. This agent also inhibits elongation factor 1-a, thereby interfering with protein synthesis, and induces G1 arrest and G2 blockade, thereby inhibiting tumor cell growth. Synonyms: aplidin; aplidine; plitidepsin; dehydrodidemnin B. Grades: >98%. CAS No. 137219-37-5. Molecular formula: C57H87N7O15. Mole weight: 1110.34. | |
| Plitidepsin | Plitidepsin (Aplidine) is a potent anti-cancer agent by targeting eEF1A2 ( K D =80?nM) [1]. Plitidepsin possesses antiviral activity and is against SARS-CoV-2 with an IC 90 of 0.88 nM. Plitidepsin is usually used for multiple myeloma and advanced cancer research, and has the potential for COVID-19 research [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: Aplidine; PM90001. CAS No. 137219-37-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16050. | |
| Plitidepsin | Plitidepsin. Uses: Designed for use in research and industrial production. Product Category: Coronavirus and Solid Tumor Clinical Raw Materials. CAS No. 137219-37-5. Purity: >98%. Product ID: ACM137219375. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Plixorafenib | PLX8394 is a potent and selective BRaf inhibitor, with an IC 50 of appr 5 nM for BRAF V600E. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PLX8394; FORE8394. CAS No. 1393466-87-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18972. | |
| PLL coated Fe2O3 nanoparticles | PLL coated Fe2O3 nanoparticles. Group: Nanopowders. CAS No. 1317-61-9. |  |
| PlnA-17 | PlnA-17 is an antibacterial peptide isolated from Lactobacillus plantarum. It has activity against gram-positive bacteria. Grades: >95%. Molecular formula: C97H153N25O20. Mole weight: 1989.44. | |
| PlnA-22 | PlnA-22 is an antibacterial peptide isolated from Lactobacillus plantarum. It has activity against gram-positive bacteria. Synonyms: Tyr-Ser-Leu-Gln-Met-Gly-Ala-Thr-Ala-Ile-Lys-Gln-Val-Lys-Lys-Leu-Phe-Lys-Lys-Trp-Gly-Trp. Grades: >97%. Molecular formula: C125H195N31O28S. Mole weight: 2612.17. | |
| Plozalizumab | Plozalizumab (MLN-1202) is a specific humanized anti- CCR2 antibody. Plozalizumab can be used for malignant melanoma research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MLN-1202. CAS No. 1610761-46-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99781. | |
| PLP (139-151) | PLP (139-151) is amino acid residue 139 to 151 of myelin proteolipid protein (PLP) used to induce experimental autoimmune encephalomyelitis (EAE). Uses: Scientific research. Group: Peptides. CAS No. 131334-43-5. Pack Sizes: 5 mg. Product ID: HY-P0129. | |
| PLP (139-151) | PLP (139-151). Group: Biochemicals. Grades: Purified. CAS No. 122018-58-0. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| PLP 139-151 | PLP 139-151 is the 139-151 amino acid residue of myelin protein (PLP), used to induce experimental autoimmune encephalomyelitis (EAE). Synonyms: Myelin Proteolipid Protein (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat); His-Cys-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe; L-histidyl-L-cysteinyl-L-leucyl-glycyl-L-lysyl-L-tryptophyl-L-leucyl-glycyl-L-histidyl-L-prolyl-L-alpha-aspartyl-L-lysyl-L-phenylalanine. Grades: >98%. CAS No. 131334-43-5. Molecular formula: C72H104N20O16S. Mole weight: 1537.79. | |
| PLpro inhibitor | PLpro inhibitor is a potent inhibitor of papain-like protease (PLpro) with an IC 50 of 2.6 μM [1]. PLpro inhibitor inhibits SARS-CoV-2 PLpro with an IC 50 of 5.0 μM and an EC 50 of 21.0 μM [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1093070-14-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17542. | |
| PLpro inhibitor | Cas No. 1093070-14-4. | |
| PLS-123 | PLS-123 is a novel covalent irreversible Bruton's Tyrosine Kinase inhibitor. PLS-123 shows potent anti-proliferative effects in multiple cellular and in vivo preclinical models of B-cell lineage malignancy. PLS-123 may become a drug candidate for treatment of B cell cancers. Uses: B cell cancers. Synonyms: PLS-123; PLS 123; PLS123. N- (2- ( (3- (2-acrylamidoacetamido) phenyl) amino) pyrimidin-5-yl) -2-methyl-5- (3- (trifluoromethyl) benzamido) benzamide. Grades: 98%. CAS No. 1431727-04-6. Molecular formula: C31H26F3N7O4. Mole weight: 617.59. | |
| Plumbagin | Plumbagin (2-Methyljuglone) is a naphthoquinone isolated from Plumbago zeylanica , exhibits anticancer and antiproliferative activities [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 2-Methyljuglone. CAS No. 481-42-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N1497. | |
| Plumbagin | Plumbagin, a natural 1,4-naphthoquinone first isolated from plants of the genus Plumbago, induces apoptosis in cancer cells. Plumbagin exhibited effective cell growth inhibition via inducing cancer cells to undergo G2/M phase arrest and apoptosis. Synonyms: 5-Hydroxy-2-methyl-1,4-naphthalenedione; 2-Methyljuglone; 5-Hydroxy-2-methyl-1,4-naphthoquinone; NSC 236613; NSC 688284; Plumbagine; Plumbagone. Grades: ≥98% by HPLC. CAS No. 481-42-5. Molecular formula: C11H8O3. Mole weight: 188.18. | |
| Plumbagin | Plumbagin. Group: Biochemicals. Grades: Purified. CAS No. 481-42-5. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Plumieride | Plumieride is isolated from the herb of Himatanthus fallax. It shows strong fungitoxicity against some dermatophytes. Synonyms: Agoniadin. Grades: 98%. CAS No. 511-89-7. Molecular formula: C21H26O12. Mole weight: 470.42. | |
| Pluracidomycin A1 | Pluracidomycin A1 is a carbapenem antibiotic produced by Str. pluracidomyceticus nov. sp. It has anti-gram-positive bacteria and gram-negative bacteria activity, and has the effect of inhibiting β-lactamase. Synonyms: 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 7-oxo-3-sulfo-6-(1-(sulfooxy)ethyl)-, (5R-(5alpha,6beta(S*)))-; Pluracidomycin; Pluracidomycin A; SF 2103 A. Grades: >98%. CAS No. 82138-64-5. Molecular formula: 9H11NO10S2. Mole weight: 357.31. | |
| Pluracidomycin B | Pluracidomycin B is a carbapenem antibiotic produced by Str. pluracidomyceticus nov. sp. It has anti-gram-positive bacteria and gram-negative bacteria activity, and has the effect of inhibiting β-lactamase. CAS No. 82138-65-6. Molecular formula: C11H13NO10S2. Mole weight: 383.35. | |
| Pluracidomycin C1 | Pluracidomycin C1 is a carbapenem antibiotic produced by Str. pluracidomyceticus nov. sp. It has anti-gram-positive bacteria and gram-negative bacteria activity, and has the effect of inhibiting β-lactamase. Synonyms: Pluracidomycin C. CAS No. 82138-66-7. Molecular formula: C10H13NO10S2. Mole weight: 371.34. | |
| Pluraflavin A | Pluraflavin A is an antitumor antibiotic produced by Saccharothrix sp. DSM 12931. Pluraflavin A has the effect of inhibiting the transcription of glucose-6-phosphatase gene and has good anti-proliferation activity on tumor cells. Molecular formula: C43H54N2O14. Mole weight: 822.89. | |
| Pluraflavin C | Pluraflavin C is an antitumor antibiotic produced by Saccharothrix sp. DSM 12931. It has good anti-proliferation activity on tumor cells. Molecular formula: C43H56N2O15. Mole weight: 840.91. | |
| Pluraflavin E | Pluraflavin E is an antitumor antibiotic produced by Saccharothrix sp. DSM 12931. It has good anti-proliferation activity on tumor cells. Molecular formula: C36H41NO14. Mole weight: 711.71. | |
| Pluripotin | SC1 (Pluripotin) was identified in a cell-based chemical library screen for small molecules that regulate mouse embryonic stem (ES) cell self-renewal. SC1 is sufficient to sustain long-term self-renewal of mouse ES cells in an undifferentiated state in the absence of LIF, feeder cells, or serum. SC1 acts through dual inhibition of extracellular signal-regulated kinase 1 (ERK1) and Ras GTPase-activating protein (Ras-GAP). Mouse ES cells maintained in the presence of SC1 retain their ability to differentiate into cells representing all three germ layers in vitro, form chimeric mouse, and contribute to germ line in vivo. Uses: Self-renewal. Synonyms: SC-1; SC 1; SC1; Pluripotin. Grades: 0.98. CAS No. 839707-37-8. Molecular formula: C27H25F3N8O2. Mole weight: 550.54. | |
| Pluripotin | Pluripotin is a dual inhibitor of ERK1 and RasGAP with K D s of 98 nM and 212 nM, respectively. Pluripotin also inhibits RSK1 , RSK2 , RSK3 , and RSK4 with IC 50 s of 0.5, 2.5, 3.3, and 10.0 μM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SC1. CAS No. 839707-37-8. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10579. | |
| Pluripotin | Pluripotin is a dual inhibitor of extracellular signal-regulated kinase 1 (ERK1, MAPK3) and RasGAP. Pluripotin has been shown to maintain embryonic stem cell (ESC) self-renewal. When combined with leukemia inhibitory factor, Pluripotin greatly promotes derivation of embryonic stem cell lines from refractory strains. Group: Biochemicals. Alternative Names: N-[3-[7-[ (1, 3-Dimethyl-1H-pyrazol-5-yl) amino]-1, 4-dihydro-1-methyl-2-oxopyrimido[4, 5-d]pyrimidin-3 (2H) -yl]-4-methylphenyl]-3- (trifluoromethyl) benzamide; N-[3-[7- (2, 5-Dimethyl-2H-pyrazol-3-ylamino) -1-methyl-2-oxo-1, 4-dihydro-2H-pyrimido[4, 5-d]pyrimidin-3-yl]-4-methylphenyl]-3-trifluoromethyl-benzamide; SC 1; Stemolecule SC 1. Grades: Highly Purified. CAS No. 839707-37-8. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Pluripotin (SC-1, SC1) | Pluripotin (SC-1, SC1). Group: Biochemicals. Alternative Names: N- (3- (7- (1, 3-dimethyl-1H-pyrazol-5-ylamino) -1-methyl-2-oxo-1, 2-dihydropyrimido[4, 5-d]pyrimidin-3 (4H) -yl) -4-methylphenyl) -3- (trifluoromethyl) benzamide. Grades: Highly Purified. CAS No. 839707-37-8. Pack Sizes: 10mg. Molecular Formula: C27H25F3N8O2 , Molecular Weight: 550.5. US Biological Life Sciences. | Worldwide |
| PluriSln 1 | PluriSln 1 is an inhibitor of stearoyl-CoA desaturase 1 (SCD1). It is useful for eliminating undifferentiated human pluripotent stem cells (hPSCs) from culture by selectively inducing apoptosis in these cells. Additionally, pluriSln 1 induces endoplasmic reticulum stress, reduces protein synthesis, and prevents teratoma formation in immunocompromised mice models. Synonyms: N'-phenylisonicotinohydrazide; N'-phenylpyridine-4-carbohydrazide. Grades: >98%. CAS No. 91396-88-2. Molecular formula: C12H11N3O. Mole weight: 213.24. | |
| PluriSln 1 (4-Pyridinecarboxylic acid 2-phenylhydrazide) | PluriSln 1 (4-Pyridinecarboxylic acid 2-phenylhydrazide). Group: Biochemicals. Grades: Highly Purified. CAS No. 91396-88-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PluriSln 1 (NSC 14613, 4-Pyridinecarboxyl icacid, 2-phenylhydrazide) | PluriSln 1 (NSC 14613, 4-Pyridinecarboxyl icacid, 2-phenylhydrazide). Group: Biochemicals. Alternative Names: N'-phenylpyridine-4-carbohydrazide. Grades: Highly Purified. CAS No. 91396-88-2. Pack Sizes: 50mg. Molecular Formula: C12 H11 N3, Molecular Weight: 213.2. US Biological Life Sciences. | Worldwide |
| Pluronic | Pluronic. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Pluronic;Poloxamer;Polyethylene-polypropylene glycol;POP/POE condensate;Synperonic. Product Category: Heterocyclic Organic Compound. CAS No. 9003-11-6. Molecular formula: C5H10O2. Mole weight: HO(C2H4O)a(C3H6O)b(C2H4O)aH. Product ID: ACM2594628. Alfa Chemistry ISO 9001:2015 Certified. | |
| Pluronic F-127 | 100g Pack Size. Group: Detergents. Formula: (C3H6O ·C2H4O)x. CAS No. 9003-11-6. Prepack ID 90030405-100g. Molecular Weight 304.29. See USA prepack pricing. |  |
| Pluronic F-127 | Pluronic F-127 is a nonionic, surfactant polyol (molecular weight approximately 12,500 daltons) that has been found to facilitate the solubilization of water-insoluble dyes and other materials in physiological media. Group: Biochemicals. Alternative Names: Poloxamer 407. Grades: Cell Culture Grade. CAS No. 9003-11-6. Pack Sizes: 250g, 500g, 1Kg. Molecular Formula: (C3H6O·C2H4O)x, Molecular Weight: Polymer. US Biological Life Sciences. | Worldwide |
| Pluronic F-127, 20% DMSO | Pluronic F-127 in DMSO is a nonionic, surfactant polyol (molecular weight approximately 12,500 daltons) that has been found to facilitate the solubilization of water-insoluble dyes and other materials in physiological media. Pluronic F-127 is commonly used to help disperse the acetoxymethyl (AM) esters of our ion indicators as well as our cell tracer dyes such as CFDA-SE.Pluronic F-127 (Poloxamer 407) is a hydrophilic non-ionic surfactant of the more general class of copolymers known as poloxamers. Poloxamer 407 is a triblock copolymer consisting of a central hydrophobic block of polypropylene glycol flanked by two hydrophilic blocks of polyethylene glycol. The approximate lengths of the two PEG blocks is 101 repeat units while the approximate length of the propylene gycol block is 56 repeat units. Group: Biochemicals. Alternative Names: Poloxamer 407; Synperonic PE/F 127. Grades: Purified. CAS No. 9003-11-6. Pack Sizes: 10ml, 25ml, 50ml. Molecular Formula: (C3H6O·C2H4O)x. US Biological Life Sciences. | Worldwide |
| Pluronic F-68 | 500g Pack Size. Group: Analytical Reagents, Biochemicals, Building Blocks, Diagnostic Raw Materials. Formula: (C3H6OC2H4O)x. CAS No. 9003-11-6. Prepack ID 89483155-500g. See USA prepack pricing. | |
| Pluronic® F-68 (PE 6800) | Cell membrane stabilizer; anti-foaming agent. Pluronic® PE 6800 is a low-foaming, nonionic surfactant. It is a block copolymer in which the central polypropylene glycol group is flanked by two polyethylene glycol groups. Group: Biochemicals. Alternative Names: F68; Poloxamer 188; Polyoxyethylene-polyoxypropylene block copolymer; Pluronic PE 6800. Grades: Highly Purified. CAS No. 9003-11-6. Pack Sizes: 250g, 500g, 1Kg. Molecular Formula: (C3H6O.C2H4O)x. US Biological Life Sciences. | Worldwide |
| Pluronic P-105 | Pluronic P105 is a difunctional block copolymer surfactant terminating in primary hydroxyl groups. A nonionic surfactant that is 100% active and relatively nontoxic. Group: Biochemicals. Alternative Names: P105, Polyoxypropylene-polyoxyethylene Block Copolymer, Methyl-oxirane polymer with oxirane. Grades: Purified. CAS No. 9003-11-6. Pack Sizes: 10g, 25g, 100g, 500g. US Biological Life Sciences. | Worldwide |
| plus-end-directed kinesin ATPase | Microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (α) chains (110 kDa) and two or more light (β) chains (65-75 kDa). Also hydrolyses GTP. Group: Enzymes. Synonyms: kinesin. Enzyme Commission Number: EC 3.6.4.4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4706; plus-end-directed kinesin ATPase; EC 3.6.4.4; kinesin. Cat No: EXWM-4706. |  |
| Pluviatolide | Pluviatolide is a butyrolactone lignan first isolated from the Australian native plant, Zanthoxylum pluviatile. It has a variety of biological activities, including antioxidant, enzyme inhibitory effect and antispasmodic properties. Synonyms: (-)-Pluviatolide; 2(3H)-Furanone, 4-(1,3-benzodioxol-5-ylmethyl)dihydro-3-((4-hydroxy-3-methoxyphenyl)methyl)-, (3R-trans)-; 3α-(4-Hydroxy-3-methoxybenzyl)-4β-(1,3-benzodioxole-5-ylmethyl)-4,5-dihydrofuran-2(3H)-one; 4,5-Dihydro-4β-[(1,3-benzodioxole-5-yl)methyl]-3α-(4-hydroxy-3-methoxybenzyl)furan-2(3H)-one; trans-Pluviatolide; (3R,4R)-4-(benzo[d][1,3]dioxol-5-ylmethyl)-3-(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one. Grades: ≥95% by HPLC. CAS No. 28115-68-6. Molecular formula: C20H20O6. Mole weight: 356.37. | |
| PLX4032 (Vemurafenib) | Vemurafenib selective BRAFV600E kinase inhibitor; an antitumor agent. Vemurafenib functions by inhibiting the proliferation and mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase and ERK phosphorylation in a panel of tumor cell lines, including melanoma cell lines expressing BRAFV600E or other mutant BRAF proteins altered at codon 600. Group: Biochemicals. Alternative Names: N-[3-[[5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide; PLX4032; RG7204; RO51-85426; Zelboraf. Grades: Highly Purified. CAS No. 918504-65-1. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. US Biological Life Sciences. | Worldwide |
| PLX4720 | PLX4720 is a 7-azaindole derivative that inhibits B-Raf(V600E) with an IC(50) of 13 nM, defines a class of kinase inhibitor with marked selectivity in both biochemical and cellular assays. PLX4720 preferentially inhibits the active B-Raf(V600E) kinase compared with a broad spectrum of other kinases, and potent cytotoxic effects are also exclusive to cells bearing the V600E allele. Synonyms: PLX 4720; PLX-4720. Grades: >98%. CAS No. 918505-84-7. Molecular formula: C17H14ClF2N3O3S. Mole weight: 413.82. | |
| PLX4720 | Potent and selective cell permeable B-Raf (V600E) and c-Raf-1 (Y340D/Y341D) inhibitor. Antitumor compound. ERK phosphorylation is potently inhibited exclusive in B-Raf(V600E)-bearing tumor cell lines. Group: Biochemicals. Alternative Names: N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide, Raf Kinase Inhibitor V. Grades: Highly Purified. CAS No. 918505-84-7. Pack Sizes: 5mg, 25mg. Molecular Formula: C??H??ClF?N?O?S. US Biological Life Sciences. | Worldwide |
| PLX51107 | PLX51107 is a potent and selective BET inhibitor with modest preference for bromodomain-1 (BD1) versus bromodomain-2 (BD2). It blocks the interaction mediated by the four BET family proteins. Synonyms: (S)-4-(6-(3,5-dimethylisoxazol-4-yl)-1-(1-(pyridin-2-yl)ethyl)-1H-pyrrolo[3,2-b]pyridin-3-yl)benzoic acid; PLX 51107; PLX-51107. CAS No. 1627929-55-8. Molecular formula: C26H22N4O3. Mole weight: 438.48. | |
| PLX5622 | PLX5622 Inhibitor. Uses: Scientific use. Product Category: T7100. CAS No. 1303420-67-8. |  |
| PLX5622 fumarate | PLX5562 is a highly selective brain-penetrant CSF1R inhibitor. In the 5xFAD mouse model of AD, plaques fail to form in the parenchymal space following microglial depletion, except in areas containing surviving microglia. Microglia appear to contribute to multiple facets of AD etiology - microglia appear crucial to the initial appearance and structure of plaques, and following plaque formation, promote a chronic inflammatory state modulating neuronal gene expression changes in response to Aβ/AD pathology. PLX5622 demonstrated desirable PK properties in mice, rats, dogs, and monkeys with a brain penetrance of ~20%. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PLX5622; PLX-5622; PLX 5622; PLX5622 fumarate. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2749102-07-4. Molecular formula: C46H42F4N10O6. Mole weight: 906.9. Purity: >98%. IUPACName: 6-fluoro-N-((5-fluoro-2-methoxypyridin-3-yl)methyl)-5-((5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)pyridin-2-amine hemifumarate. Canonical SMILES: CC1=CN=C(NC=C2CC3=C(F)N=C(NCC4=CC(F)=CN=C4OC)C=C3)C2=C1.O=C(O)/C=C/C(O)=O.CC5=CN=C(NC=C6CC7=C(F)N=C(NCC8=CC(F)=CN=C8OC)C=C7)C6=C5. Product ID: ACM2749102074. Alfa Chemistry ISO 9001:2015 Certified. Categories: 6-fluoro-N-((5-fluoro-2-methoxypyridin-3-yl)methyl)-5-((5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)pyridin-2-amine fumarate. | |
| PLX-647 | PLX-647 is PLX647 is a potent inhibitors of both FMS and KIT that show strong selectivity compared with other kinases. In the in vitro enzymatic assay, PLX647 inhibits FMS with IC50 = 0.028μM and KIT with IC50 = 0.016 μM. PLX647 represents a unique class of kinase inhibitors with unique dual FMS and KIT specificity. Synonyms: PLX-647; PLX 647; PLX647. Grades: 0.98. CAS No. 873786-09-5. Molecular formula: C21H17F3N4. Mole weight: 382.39. | |
| PLX 647 dihydrochloride | PLX 647 dihydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PLX 647 dihydrochloride | PLX 647 is a potent dual KIT/Fms inhibitor (IC50= 16 and 28 nM respectively). PLX 647 blocks activation of macrophages, osteoclasts and mast cells in both cell based and in vivo inflammation models. Synonyms: PLX 647 dihydrochloride; PLX647 dihydrochloride; PLX-647 dihydrochloride; 5-(1H-Pyrrolo[2,3-b]pyridin-3-ylmethyl)-N-[[4-(trifluoromethyl)phenyl]methyl]-2-pyridinamine dihydrochloride. Grades: ≥97% by HPLC. CAS No. 1779796-38-1. Molecular formula: C21H17F3N4.2HCl. Mole weight: 455.3. | |
| PLX-7683 | PLX-7683, a pyrrolopyridine derivative, has been found to be a paradox breaker that was studied to exhibit more durable efficacy and better safety than some former RAF inhibitors. Synonyms: PLX7683; PLX-7683; PLX 7683; Sulfamide, N'-[4-[[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-3,5-difluorophenyl]-N-ethyl-N-methyl-. Grades: 98%. CAS No. 1652573-86-8. Molecular formula: C23H19ClF2N4O3S. Mole weight: 504.94. | |
| PLX7904 | PLX7904, also known as PB04, is a potent and selective paradox-breaker RAF inhibitor. PB04 is able to efficiently inhibit activation of ERK1/2 in mutant BRAF melanoma cells but does not hyperactivate ERK1/2 in mutant RAS-expressing cells. Synonyms: PLX7904; PLX-7904; PLX 7904; PB04; PB-04; PB 04; paradox-breaker-04. Grades: 98%. CAS No. 1393465-84-3. Molecular formula: C24H22F2N6O3S. Mole weight: 512.54. | |
| PM-1 | PM-1, a derivative of Thioflavin-T (ThT; HY-D0218), is a small but highly specific plasma membrane (PM) fluorescent dye for specific and long-time membrane imaging of living and fixed cells. PM-1 is embedded directly into the cell membrane and exhibits a very long retention time on the plasma membrane with a half-life of approximately 15 h. PM-1 can be used in combination with protein labeling probes to study ectodomain shedding and endocytosis processes of cell surface proteins [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 1449483-78-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156404. | |
| PM 102 | PM 102, an antagonist of heparin, is a peptide that reverses the anticoagulant effect of heparin. Synonyms: PM 102; PM102; PM-102; AEARARRAAARAARRAKK (AEARARRAAARAARRA)PX (AEARARRAAARAARRA)EN. CAS No. 1234564-95-4. Molecular formula: C235H425N111O64. Mole weight: 5830. | |
| PM-94128 | PM-94128. Synonyms: PM 94128; PM94128. CAS No. 182292-49-5. Molecular formula: C22H34N2O6. Mole weight: 422.5. | |
| PMA | PMA, extracted from seeds of Euphorbia lathyris L, is a phorbol ester that is commonly used to activate certain types of protein kinase C (PKC), including group A (α, βI, βII, γ) and group B (δ, ε, η, θ) isoforms. It has been shown to inhibit apoptosis induced by the Fas antigen, but PMA induces apoptosis in HL-60 promyelocytic leukemia cells. Synonyms: Phorbol-12-Myristate-13-Acetate; 12-O-Tetradecanoylphorbol 13-acetate, 4β, 9α, 12β, 13α, 20-Pentahydroxytiglia-1, 6-dien-3-one 12-tetradecanoate; 12 Myristoyl 13 acetylphorbol; 12 O Tetradecanoyl Phorbol 13 Acetate; 12-Myristoyl-13-acetylphorbol; 12-O-Tetradecanoyl Phorbol 13-Acetate; 13-Acetate, 12-O-Tetradecanoyl Phorbol; Acetate, Phorbol Myristate; Acetate, Tetradecanoylphorbol; Myristate Acetate, Phorbol; Phorbol 13-Acetate, 12-O-Tetradecanoyl; Phorbol Myristate Acetate; Tetradecanoylphorbol Acetate; Tetradecanoylphorbol Acetate, 4a alpha Isomer; Tetradecanoylphorbol Acetate, 4a alpha-Isomer. Grades: ≥95%. CAS No. 16561-29-8. Molecular formula: C36H56O8. Mole weight: 616.83. | |
| p-Maleimidobenzoyl N-hydroxysuccinimide | p-Maleimidobenzoyl N-hydroxysuccinimide. Group: Biochemicals. Alternative Names: MBS-2. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| p-Maleimidobenzoyl N-hydroxysuccinimide ≥95% | p-Maleimidobenzoyl N-hydroxysuccinimide ≥95%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg. US Biological Life Sciences. | Worldwide |
| p-Maleimidophenyl isocyanate | p-Maleimidophenyl isocyanate. Group: Biochemicals. Alternative Names: PMPI. Grades: Highly Purified. CAS No. 123457-83-0. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. US Biological Life Sciences. | Worldwide |
| p-Maleimidophenyl isocyanate 98+% (NMR) | p-Maleimidophenyl isocyanate 98+% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences. | Worldwide |
| PMAP-36 | PMAP-36 is an antibacterial peptide isolated from Sus scrofa. It has activity against gram-positive bacteria and gram-negative bacteria. Grades: >97%. | |
| PME-1 Inhibitor, AMZ-30 | A cell-permeable sulfonyl acrylonitrile compound that acts as a potent and irreversible inhibitor of protein phosphatase methylesterase-1 (PME-1; IC50=600nM and 2.5uM in human cell lysates and in HEK 293T cells, (respectively) with 100-fold greater selectivity over other serine hydrolases; does not function as a general thiol-reactive probe. Shown to lower demethylated PP2A levels by ~80% at 20uM with elevated methylated PP2A (protein phosphatase 2A) form in PME-1 overexpressing HEK 293T cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??FN?O?S?, Molecular Weight: 462.6. US Biological Life Sciences. | Worldwide |
| PMEL (25-33) | PMEL (25-33) is a peptide derived from Melanocyte Protein PMEL 17, a 100 kDa type I transmembrane glycoprotein that is expressed primarily in pigment cells of the skin and eye. Synonyms: gp100 (25-33); Melanocyte protein PMEL (25-33). | |
| p-Menth-1-en-8-yl benzoate | p-Menth-1-en-8-yl benzoate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: p-Menth-1-en-8-yl benzoate, EINECS 275-763-8, 71648-34-5. Product Category: Heterocyclic Organic Compound. CAS No. 71648-34-5. Molecular formula: C17H22O2. Mole weight: 258.355380 [g/mol]. Purity: 0.96. IUPACName: 2-(4-methylcyclohex-3-en-1-yl)propan-2-yl benzoate. Canonical SMILES: CC1=CCC(CC1)C(C)(C)OC(=O)C2=CC=CC=C2. Density: 1.034g/cm³. ECNumber: 275-763-8. Product ID: ACM71648345. Alfa Chemistry ISO 9001:2015 Certified. | |
| p-Menth-3-ene | p-Menth-3-ene. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Menthomenthene, 3-Menthene, 3-p-Menthene, delta1-p-Menthene, p-MENTH-3-ENE, p-Menth-3-ene, (R)-(+)-, 1-Isopropyl-4-methyl-1-cyclohexene, EINECS 207-896-4, BRN 1850192, Cyclohexene, 4-methyl-1-(1-methylethyl)-, CID10369, LS-89521, Cyclohexene, 4-methyl-1-(1-methylethyl)-, (R)-, 2-05-00-00053 (Beilstein Handbook Reference), 2230-69-5, 500-00-5. Product Category: Heterocyclic Organic Compound. CAS No. 500-00-5. Molecular formula: C10H18. Mole weight: 138.249920 [g/mol]. Purity: 0.96. IUPACName: 4-methyl-1-propan-2-ylcyclohexene. Canonical SMILES: CC1CCC(=CC1)C(C)C. Density: 0.813g/cm³. ECNumber: 207-896-4. Product ID: ACM500005. Alfa Chemistry ISO 9001:2015 Certified. | |
| P-mentha-1,2,8-triol | P-mentha-1,2,8-triol. Uses: For analytical and research use. Group: Impurity standards. CAS No. 62014-81-7. Molecular Formula: C10H20O3. Mole Weight: 188.27. Catalog: APB62014817. |  |
| p-Mentha-1(7),2-diene | p-Mentha-1(7),2-diene. Uses: Designed for use in research and industrial production. Additional or Alternative Names: p-mentha-1(7),2-diene ;β-phellandrene,1(7)-2-p-menthadiene;Cyclohexene, 3-methylene-6-(1-methylethyl)-;3-methylidene-6-propan-2-yl-cyclohexene;1(7),2-p-Menthadiene;3-Methylene-6-isopropylcyclohexene;6-Isopropyl-3-methylene-1-cyclohexene;4-Isopropyl-1-methylene-2-cyclohexene. Product Category: Heterocyclic Organic Compound. CAS No. 555-10-2. Molecular formula: C10H16. Mole weight: 136.23404. Density: 0.8517 g/cm³. Product ID: ACM555102. Alfa Chemistry ISO 9001:2015 Certified. Categories: BETA-PHELLANDRENE. | |
| p-Mentha-6,8-dien-2-on | p-Mentha-6,8-dien-2-on. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Karvon, CARVONE, Carvol, 1-Carvone, l-Carvone, Carvon. alpha.-Carvone, Spearmint oil, Curled mint oil, d-Carvone, Oils, spearmint, Carvone (natural), Mint oil, p-Mentha-6,8-dien-2-one, Oil of crispmint, (R)-Carvone, D-Cavone, Carvone [ISO], Spearmint terpenes, (-)-Carvone. Product Category: Heterocyclic Organic Compound. CAS No. 22327-39-5. Molecular formula: C10H14O. Mole weight: 150.217560 [g/mol]. Purity: 0.96. IUPACName: 2-methyl-5-prop-1-en-2-ylcyclohex-2-en-1-one. Canonical SMILES: CC1=CCC(CC1=O)C(=C)C. ECNumber: 202-759-5. Product ID: ACM22327395. Alfa Chemistry ISO 9001:2015 Certified. | |
| p-Mentha-8-thiol-3-one | p-Mentha-8-thiol-3-one. Group: Biochemicals. Alternative Names: 8-Thiomenthone; 8-Mercapto-p-menthane-3-one. Grades: Highly Purified. CAS No. 38462-22-5. Pack Sizes: 10g, 25g, 50g, 100g. Molecular Formula: C10H18OS. US Biological Life Sciences. | Worldwide |
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