A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
rel- (8R, 8'R) -dimethyl- (7S, 7'R) -bis (3, 4-methylenedioxyphenyl) tetrahydro-furan. Group: Biochemicals. CAS No. 178740-32-4. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Relacatib
Relacatib, also known as SB-462795, is a potent and orally bioavailable small molecule inhibitor of cathepsin K that inhibits bone resorption both in vitro in human tissue and in vivo in cynomolgus monkeys. SB-462795 is a potent inhibitor of human cathepsins K, L, and V (K(i, app)=41, 68, and 53 pM, respectively) that exhibits 39-300-fold selectivity over other cathepsins. Synonyms: SB-462795; SB462795; SB 462795; GSK-462795; GSK 462795; GSK462795; N-((S)-4-methyl-1-(((4S,7R)-7-methyl-3-oxo-1-(pyridin-2-ylsulfonyl)azepan-4-yl)amino)-1-oxopentan-2-yl)benzofuran-2-carboxamide. CAS No. 362505-84-8. Molecular formula: C27H32N4O6S. Mole weight: 540.63.
Relacorilant
Relacorilant is an antagonist of glucocorticoid receptor which is under development for the treatment of Cushing's syndrome. CAS No. 1496510-51-0. Molecular formula: C27H22F4N6O3S. Mole weight: 586.6.
Relacorilant
Relacorilant is a potent, selective and orally bioavailable glucocorticoid receptor antagonist, with a K i of 7.2 nM in HepG2 TAT assay, and also shows K i s of 12, 81.2, 210 nM for rat, human and monkey glucocorticoid receptor in cell-based assay, respectively. Relacorilant has the potential for Cushings syndrome treatment. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CORT 125134. CAS No. 1496510-51-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109042.
Relamorelin
Relamorelin is a synthetic, centrally penetrant, selective agonist of the ghrelin/growth hormone secretagogue receptor (GHSR). It is potentially useful for the treatment of diabetic gastroparesis, chronic idiopathic constipation, and anorexia nervosa. It is a pentapeptide and an analogue of ghrelin. It produces increases in plasma growth hormone, prolactin, and cortisol levels, and increases appetite in humans. It is under development by Rhythm Pharmaceuticals and is in phase II clinical trials. Uses: Relamorelin is potentially useful for the treatment of diabetic gastroparesis, chronic idiopathic constipation, and anorexia nervosa. Synonyms: BIM28131; BIM 28131; BIM-28131; BIM-28163; BIM 28163; BIM28163; RM131; RM-131; RM 131; Relamorelin;N-((R)-3-(benzo[b]thiophen-3-yl)-1-(((R)-1-(((S)-1-((4-carbamoylpiperidin-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)amino)-1-oxopropan-2-yl)piperidine-3-carboxamide;4. Grades: 98%. CAS No. 661472-41-9. Molecular formula: C43H50N8O5S. Mole weight: 790.98.
Relamorelin TFA
Relamorelin (RM-131) TFA, a pentapeptide ghrelin analog, is a selective ghrelin/growth hormone secretagogue receptor (GHSR) agonist with a K i of 0.42 nM for GHS-1a receptor. Relamorelin TFA is centrally penetrant. Relamorelin TFA increases growth hormone levels and accelerates gastric emptying. Relamorelin TFA has the potential for cachexia, gastroparesis, and gastric/intestinal dysmobility disorders research [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Peptides. Alternative Names: RM-131 TFA; BIM-28131 TFA. CAS No. 2863659-22-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19884B.
Relative Density Standard (15°C)
UKAS ISO/IEC17025 and ISO 17034 certified, Relative Density 15/4 0.8494 at 15 °C. Group: Certified reference materials (crms).
Relatlimab
Relatlimab (BMS-986016) is a human monoclonal antibody anti-LAG-3 antibody generated by immunization of transgenic mice bearing human immunoglobulin miniloci with recombinant LAG-3 protein. Relatlimab blocks LAG-3/MHC II interaction with an IC 50 value of 0.67 nM and LAG-3/FGL1 interaction with an IC 50 value of 0.019 nM. Relatlimab can be used in research of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BMS-986016. CAS No. 1673516-98-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99156.
Relaxin H2 (human)
Relaxin H2 (human), a recombinant human relaxin targeting the RLN receptor, is a vasoactive peptide hormone with antifibrotic activity. Relaxin H2 is a pregnancy hormone with cardioprotective activity. It is the main storage and circulation subtype of relaxin peptide hormone in humans. Synonyms: Serelaxin; (Pyr-Leu-Tyr-Ser-Ala-Leu-Ala-Asn-Lys-Cys-Cys-His-Val-Gly-Cys-Thr-Lys-Arg-Ser-Leu-Ala-Arg-Phe-Cys-OH)A (H-Asp-Ser-Trp-Met-Glu-Glu-Val-Ile-Lys-Leu-Cys-Gly-Arg-Glu-Leu-Val-Arg-Ala-Gln-Ile-Ala-Ile-Cys-Gly-Met-Ser-Thr-Trp-Ser-OH)B (Disulfide bridge: Cys10A-Cys15A, Cys11A-Cys11B, Cys24A-Cys23B); L-alpha-aspartyl-L-seryl-L-tryptophyl-L-methionyl-L-alpha-glutamyl-L-alpha-glutamyl-L-valyl-L-isoleucyl-L-lysyl-L-leucyl-L-cysteinyl-glycyl-L-arginyl-L-alpha-glutamyl-L-leucyl-L-valyl-L-arginyl-L-alanyl-L-glutaminyl-L-isoleucyl-L-alanyl-L-isoleucyl-L-cysteinyl-glycyl-L-methionyl-L-seryl-L-threonyl-L-tryptophyl-L-serine (11->11'),(23->24')-bis(disulfide) compound with L-pyroglutamyl-L-leucyl-L-tyrosyl-L-seryl-L-alanyl-L-leucyl-L-alanyl-L-asparagyl-L-lysyl-L-cysteinyl-L-cysteinyl-L-histidyl-L-valyl-glycyl-L-cysteinyl-L-threonyl-L-lysyl-L-arginyl-L-seryl-L-leucyl-L-alanyl-L-arginyl-L-phenylalanyl-L-cysteine (10'->15')-disulfide; Human relaxin II. Grades: ≥95% by HPLC. CAS No. 99489-94-8. Molecular formula: C256H408N74O74S8. Mole weight: 5963.04.
Relaxin H3 (human)
Relaxin H3, a specific ligand for the leucine-rich repeat-containing G protein-coupled receptor LGR7, exerts anti-fibrosis effects through relaxin receptor RXFP1 and may enhance the collagen-inhibiting effect of relaxin H2. Synonyms: (H-Asp-Val-Leu-Ala-Gly-Leu-Ser-Ser-Ser-Cys-Cys-Lys-Trp-Gly-Cys-Ser-Lys-Ser-Glu-Ile-Ser-Ser-Leu-Cys-OH)A (H-Arg-Ala-Ala-Pro-Tyr-Gly-Val-Arg-Leu-Cys-Gly-Arg-Glu-Phe-Ile-Arg-Ala-Val-Ile-Phe-Thr-Cys-Gly-Gly-Ser-Arg-Trp-OH)B (Disulfide bridge: Cys10A-Cys15A, Cys11A-Cys10B, Cys24A-Cys22B). Grades: ≥95% by HPLC. CAS No. 1158181-62-4. Molecular formula: C237H374N70O69S6. Mole weight: 5500.31.
Relcovaptan is a non-peptide vasopressin receptor antagonist, selective for the V1a subtype. It has shown positive initial results in tests against Raynaud's disease, dysmenorrhoea, and tocolysis. Uses: Hormone antagonists. Synonyms: (2S)-1-[[(2R,3S)-5-Chloro-3-(2-chlorophenyl)-1-[(3,4-dimethoxyphenyl)sulfonyl]-2,3-dihydro-3-hydroxy-1H-indol-2-yl]carbonyl]-2-pyrrolidinecarboxamide; [2R-[2α(S*),3β]]-1-[[5-Chloro-3-(2-chlorophenyl)-1-[(3,4-dimethoxyphenyl)sulfonyl]-2,3-dihydro-3-hydroxy-1H-indol-2-yl]carbonyl]-2-pyrrolidinecarboxamide; SR 49059. Grades: > 95%. CAS No. 150375-75-0. Molecular formula: C28H27Cl2N3O7S. Mole weight: 620.51.
Reldesemtiv
Reldesemtiv (CK-2127107) is a selective, orally active and next-generation fast skeletal muscle troponin activator (FSTA). Reldesemtiv selectively activates fast skeletal myofibrils with an EC 50 of 3.4 μM. Reldesemtiv increases exercise performance in a heart failure model [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CK-2127107. CAS No. 1345410-31-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109121.
Relebactam, a diazabicyclooctane derivative, has a broad spectrum inhibitory activity against β-lactamases. It has been studied to be probably effective in the treatment of Gram-negative bacterial infections combinated with Primaxin. Uses: Beta-lactamase inhibitors. Synonyms: MK-7655; MK 7655; MK7655. Grades: 98%. CAS No. 1174018-99-5. Molecular formula: C12H20N4O6S. Mole weight: 348.38.
Relebactam
Relebactam is a diazabicyclooctane inhibitor with activity against a wide spectrum of β-lactamases , including class A (extended-spectrum β-lactamases and KPC) and class C (AmpC) enzymes. Relebactam shows antibacterial activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-7655. CAS No. 1174018-99-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16752.
RELM-alpha from mouse
recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy.
RELM-beta from mouse
recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
RELM-b human
recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy.
RELM-gamma from mouse
recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
rel-m-nitro-threo-Chloramphenicol
rel-m-nitro-threo-Chloramphenicol is an analog of Chloramphenicol (C325030); a broad spectrum antibiotic obtained from cultures of the soil bacterium Streptomyces venezuelae. It has a broad spectrum of activity against gram-positive and gram-negative bacteria. Also antibacterial and antirickettsial. Group: Biochemicals. Grades: Highly Purified. CAS No. 138125-72-1. Pack Sizes: 5mg, 50mg. Molecular Formula: C11H12Cl2N2O5, Molecular Weight: 323.13. US Biological Life Sciences.
Worldwide
Relomycin
Relomycin. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1404-48-4. Molecular formula: C46H79NO17. Mole weight: 918.13. Catalog: APB1404484.
Relpax
A second generation triptan drug used in the treatment of migraine headaches. Group: Biochemicals. Alternative Names: 3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethyl]-1H-indole Hydrobromide; Eletriptan Hydrobromide; (R) -5-[2- (Benzenesulfonyl) ethyl]-3-[ (N-methylpyrrolidin-2-yl) methyl]-1H-indole Hydrobromide; Relert; UK 116044-04. Grades: Highly Purified. CAS No. 177834-92-3. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
rel-(R*,R*)-Bicalutamide Sulfoxide
rel-(R*,R*)-Bicalutamide Sulfoxide. Group: Biochemicals. Alternative Names: (2R) -N-[4-Cyano-3- (trifluoromethyl) phenyl]-3-[ (R) - (4-fluorophenyl) sulfinyl]-2-hydroxy-2-methylpropanamide. Grades: Highly Purified. CAS No. 1080647-25-1. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
rel-(R,R)-Voriconazole
The (R,R)-enantiomer of Voriconazole. An antifungal (systemic). An ergosterol biosynthesis inhibitor. Group: Biochemicals. Alternative Names: rel-(αR, βR)-α-(2,4-Difluorophenyl)-5-fluoro- β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol. Grades: Highly Purified. CAS No. 137330-52-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
rel-trans-Methoprene Epoxide
rel-trans-Methoprene Epoxide is a metabolite of Methoprene, a juvenile hormone (JH) analog which can be used as an insecticide that acts as a growth regulator. Synonyms: (2E)-rel-3-[(2R,3R)-3-(6-Methoxy-2,6-dimethylheptyl)-2-oxiranyl]-2-butenoic Acid 1-Methylethyl Ester; (2E)-rel-3-[(2R,3R)-3-(6-Methoxy-2,6-dimethylheptyl)oxiranyl]-2-butenoic Acid 1-Methylethyl Ester. Grades: > 95%. CAS No. 65277-96-5. Molecular formula: C19H34O4. Mole weight: 326.47.
Relugolix
Relugolix, also known as TAK-385, is a luteinizing hormone-releasing hormone (LH-RH) receptor antagonist administered orally. By preventing LH-RH from binding with the LH-RH receptor in the anterior pituitary gland and suppressing the secretion of luteinizing hormone (LH) and follicle stimulation hormone (FSH) from the anterior pituitary gland, TAK-385 controls the effect of LH and FSH on the ovary, reduces the level of estrogen in blood, which is known to be associated with the development of endometriosis and uterine fibroids, and is expected to improve the symptoms of these disorders. Uses: Androgen antagonists. Synonyms: TAK-385; N-[4-[1-[(2,6-Difluorophenyl)methyl]-5-[(dimethylamino)methyl]-1,2,3,4-tetrahydro-3-(6-methoxy-3-pyridazinyl)-2,4-dioxothieno[2,3-d]pyrimidin-6-yl]phenyl]-N'-methoxyurea; Orgovyx; RVT 601; 1-{4-[1-(2,6-difluorobenzyl)-5-dimethylaminomethyl-3-(6-methoxypyridazin-3-yl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl]phenyl}-3-methoxyurea. Grades: ≥95%. CAS No. 737789-87-6. Molecular formula: C29H27F2N7O5S. Mole weight: 623.63.
Relugolix
Relugolix (TAK-385) is a potent, orally active, nonpeptidic gonadotropin-releasing hormone (GnRH) antagonist. Relugolix possesses high affinity and potent antagonistic activity for human receptor (binding IC 50 =0.33 nM) and monkey receptor ( IC 50 =0.32 nM) compared with TAK-013 (HY-100209) [1]. Relugolix is used for the study of sex-hormone-dependent diseases, such as including endometriosis, uterine fibroids and prostate cancer et al [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-385. CAS No. 737789-87-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16474.
Remacemide
Remacemide (FPL 12924) is an orally active, non-competitive, low-affinity NMDA receptor antagonist. Remacemide shows neuroprotection activity in animal models of hypoxia and ischemic stroke. Remacemide is also an anticonvulsant, and can be used in Parkinson's disease and Huntington's disease research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FPL 12924; PR 934-423; FPL 13592. CAS No. 128298-28-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160604.
Remacemide hydrochloride
Remacemide, also known as PR-934423 and FPL 12924AA, is a non-competitive NMDA receptor antagonist, which blocks ion channel and allosteric modulatory site (IC50 = 8-68 mM). Remacemide Hydrochloride has been used in pharmaceutical studies as a potential treatment to ischemic stroke, epilepsy, Parkinson's disease and Huntington's disease. Synonyms: 2-Amino-N-(1-methyl-1,2-diphenylethyl)acetamide hydrochloride; PR-934423; PR934423 PR 934423; PR 934-423A; FPL 12924AA; Remacemide hydrochloride. Grades: ≥99% by HPLC. CAS No. 111686-79-4. Molecular formula: C17H20N2O.HCl. Mole weight: 304.82.
REMASTRAL BLUE FFRL. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Direct Blue 108;Direct fast blue FFRL. Product Category: Direct Dyes. CAS No. 1324-58-9. Molecular formula: C34H19Cl2N4Na3O11S3. Mole weight: 895.6. Product ID: ACM1324589. Alfa Chemistry ISO 9001:2015 Certified.
Remazol brilliant blue R D-xylan
Remazol Brilliant Blue R D-xylan is an exceptional biomedical compound, manifesting as a discerning chromophore, deftly illuminating the intricate web of pharmaceutical drugs or biomarkers concealed within biological substrates. Synonyms: RBB-Xylan; 4-O-Methyl-D-glucurono-D-xylan-remazol brilliant blue; 4-O-Methyl-D-glucurono-D-xylan dyed with Remazol brilliant blue R.
Remazol Brilliant Blue R-D-Xylan
Remazol Brilliant Blue R-D-Xylan. Group: Polysaccharide.
Remazol brilliant violet 5r
Remazol brilliant violet 5r. Uses: Designed for use in research and industrial production. Additional or Alternative Names: REMAZOL BRILLIANT VIOLET 5R;REACTIVE VIOLET 5;CI 18097;C.I.ReactiveViloet5(18097);C.I.Reactiveviolet5;DiamiraBrilliantViolet5R;PrimazinBrilliantViloetRL;Copper, 5-(acetylamino)-4-hydroxy-3-[[2-hydroxy-4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]azo]-2,7-naphth. Product Category: Heterocyclic Organic Compound. CAS No. 12226-38-9. Molecular formula: C20H16N3Na3O15S4. Mole weight: 735.56. Product ID: ACM12226389. Alfa Chemistry ISO 9001:2015 Certified.
N-[(S)-hydroxyphenoxyphosphinyl)-L-alanine, 2-ethylbutyl ester, 6-ester with 2-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-D-altrononitrile. CAS No. 1809249-37-3. Product ID: 8-04897. Molecular formula: C27H35N6O8P. Mole weight: 602.58. Purity: 0.98.
Remdesivir
Remdesivir (GS-5734), a nucleoside analogue with effective antiviral activity, has EC 50 s of 3.3 μM, 4.7 μM, 32 μM, 3.7 μM and 9.2 μM for SARS-CoV-2 and its variants alpha, beta, gamma and delta, respectively. Remdesivir is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-5734. CAS No. 1809249-37-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-104077.
Remdesivir
Remdesivir, an analog nucleotide inhibitor, with effectively antiviral activity in vitro against various virus, including Ebola virus, Marburg virus, HCoV-NL63, HCoV-OC43, HCoV-229E, Mouse hepatitis virus (MHV), SARS-CoV, MERS-CoV and related bat coronavirus, HKU5, and PDCoV (porcine delta-coronavirus). Remdesivir is also reported to have potential antiviral activity against a 2019 novel coronavirus (called 2019-nCoV, nCoV2019 or COVID-19). Synonyms: GS-5734; 2-ethylbutyl (2S)-2-[[[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxyoxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate. Grades: 99.78%. CAS No. 1809249-37-3. Molecular formula: C27H35N6O8P. Mole weight: 602.59.
Remdesivir
Remdesivir (GS-5734), a nucleoside analogue with effective antiviral activity, has EC50s of 3.3 μM, 4.7 μM, 32 μM, 3.7 μM and 9.2 μM for SARS-CoV-2 and its variants alpha, beta, gamma and delta, respectively. Remdesivir is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro. Uses: Designed for use in research and industrial production. Additional or Alternative Names: GS-5734; 2-Ethylbutyl ((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate. Product Category: Inhibitors. Appearance: White solid. CAS No. 1809249-37-3. Molecular formula: C27H35N6O8P. Mole weight: 602.58. Purity: 0.98. IUPACName: 2-ethylbutyl (2S)-2-[[[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxyoxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate. Canonical SMILES: CCC(CC)COC(=O)[C@H](C)N[P@](=O)(OC[C@@H]1[C@H]([C@H]([C@](O1)(C#N)C2=CC=C3N2N=CN=C3N)O)O)OC4=CC=CC=C4. Product ID: ACM1809249373. Alfa Chemistry ISO 9001:2015 Certified.
Remdesivir (Standard)
Remdesivir (Standard) is the analytical standard of Remdesivir. This product is intended for research and analytical applications. Remdesivir (GS-5734), a nucleoside analogue with effective antiviral activity, has EC 50 s of 3.3 μM, 4.7 μM, 32 μM, 3.7 μM and 9.2 μM for SARS-CoV-2 and its variants alpha, beta, gamma and delta, respectively. Remdesivir is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1809249-37-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-104077R.
Remeglurant
Remeglurant is a selective Metabotropic glutamate receptor 5 antagonist originated by Merz Pharmaceuticals. Phase-I for Drug-induced dyskinesia in USA was on-going. Uses: Drug-induced dyskinesia. Synonyms: UNII-Y7H8880HMD;(R)-(6-bromopyrazolo[1,5-a]pyrimidin-2-yl)(1-methyl-3,4-dihydroisoquinolin-2(1H)-yl)methanone. Grades: 98%. CAS No. 1309783-00-3. Molecular formula: C17H15BrN4O. Mole weight: 371.24.
Remibrutinib
Remibrutinib, is a potent and orally active bruton tyrosine kinase (BTK) inhibitor with an IC 50 value of 1 nM. Remibrutinib inhibits BTK activity with an IC 50 value of 0.023 μM in blood [1]. Remibrutinib has the potential for Chronic urticaria (CU) treatment [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LOU064. CAS No. 1787294-07-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-128757.
Remifentanil hydrochloride EP impurity B
Remifentanil hydrochloride EP impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1332691-33-4. Molecular formula: C19H26N2O5. Mole weight: 362.43. Catalog: APB1332691334.
Remifentanil Impurity1
Remifentanil Impurity1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 113231-29-1. Molecular formula: C12H18N2O. Mole weight: 206.29. Catalog: APB113231291.
Remifentanil Impurity 1 ( RTF-02)
An impurity of Remifentanil. Remifentanil is a synthetic opioid analgesic drug. It is given to patients during surgery to relieve pain and as an adjunct to an anaesthetic. Synonyms: SCHEMBL3167494; Methyl 4-cyano-4-(phenylamino)-1-piperidinepropanoate; REMIFENTANIL HYDROCHLORIDE IMPURITY M [EP IMPURITY]; 1-Piperidinepropanoic acid, 4-cyano-4-(phenylamino)-, methyl ester. Grades: > 95%. CAS No. 938184-94-2. Molecular formula: C16H21N3O2. Mole weight: 287.36.
Remifentanil Impurity 4
An intermediate in the preparation of Fentanyl analogues. Remifentanil is a synthetic opioid analgesic drug. It is given to patients during surgery to relieve pain and as an adjunct to an anaesthetic. Synonyms: 4-[(1-Oxopropyl)phenylamino]-4-piperidinecarboxylic Acid Methyl Ester. Grades: > 95%. CAS No. 72996-78-2. Molecular formula: C16H22N2O3. Mole weight: 290.37.
Remikiren
Remikiren is a renin inhibitor originated by Roche in 1996. But clinical trials for the treatment of Heart failure and Hypertension was discontinued. Uses: Heart failure; hypertension. Synonyms: (αS)-N-[(1S,2R,3S)-1-(Cyclohexylmethyl)-3-cyclopropyl-2,3-dihydroxypropyl]-α-[[(2S)-2-[[(1,1-dimethylethyl)sulfonyl]methyl]-1-oxo-3-phenylpropyl]amino]-1H-imidazole-5-propanamide; [1S-[1R*[R*(R*)],2S*,3R*]]-N-[1-(Cyclohexylmethyl)-3-cyclopropyl-2,3-dihydroxypropyl]-α-[[2-[[(1,1-dimethylethyl)sulfonyl]methyl]-1-oxo-3-phenylpropyl]amino]-1H-imidazole-4-propanamide; Ro 42-5892; Ro 42-5892/001. Grades: 95%. CAS No. 126222-34-2. Molecular formula: C33H50N4O6S. Mole weight: 630.84.
Remisporine B
Remisporine B is a polyketide and a derivative of remisporine A produced by the strain of Penicillium and has immunosuppressant activity. It inhibits LPS- or concanavalin A-induced proliferation of isolated mouse splenic lymphocytes (IC50s = 30.1 and 32.4 μg/ml, respectively). Synonyms: Remisporine B; 571194-06-4; AKOS040755735; Dimethyl (1S, 12S, 14S, 15R, 27R)-8, 14, 23-trihydroxy-6, 21-dimethyl-10, 25-dioxo-3, 13, 18-trioxaheptacyclo[13.11.1.02, 11.04, 9.012, 27.017, 26.019, 24]heptacosa-2(11), 4, 6, 8, 17(26), 19, 21, 23-octaene-12, 14-dicarboxylate. Grades: >95% by HPLC. CAS No. 571194-06-4. Molecular formula: C30H24O12. Mole weight: 576.50.
Remodelin
Remodelin, a 2-thiazolylhydrazone derivative, is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10, which acetylates both histones and microtubules. It can improve nuclear architecture, chromatin organization, and fitness of both human lamin A/C-depleted cells and HGPS-derived patient cells, and decrease markers of DNA damage in these cells. It is a useful chemical tool to study how NAT10 affects nuclear architecture and suggest alternative strategies for treating laminopathies and aging. It also has cytotoxic effects against some species of the fungus Candida. Synonyms: Remodelin; 949912-58-7; CHEMBL399572; 4-[2-(2-cyclopentylidenehydrazinyl)-1,3-thiazol-4-yl]benzonitrile4-(2-(2-cyclopentylidenehydrazinyl)thiazol-4-yl)benzonitrile. Grades: >98%. CAS No. 949912-58-7. Molecular formula: C15H14N4S. Mole weight: 282.36.
Remodelin hydrobromide
Remodelin, via inhibition of NAT10, mediates nuclear shape rescue of LMNA depleted cells by microtubule reorganization, and improves nuclear shape and fitness of HGPS cells. Synonyms: Remodelin HBr; Remodelin Hydrobromide. Grades: >98%. CAS No. 1622921-15-6. Molecular formula: C15H15BrN4S. Mole weight: 363.28.
Remogliflozin is a potent and selective inhibitor of SGLT2 (sodium-glucose cotransporter 2) with K i s of 12.4 and 26 nM for human and rat SGLT2, respectively. Remogliflozin is the active form of Remogliflozin etabonate(HY-14945) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Remogliflozin A. CAS No. 329045-45-6. Pack Sizes: 5 mg. Product ID: HY-13414.
Remogliflozin
Remogliflozin is a selective inhibitor of sodium-glucose transporter 2 (SGLT2) that promotes blood glucose to be eliminated through the urine. The prodrug Remoglifozin etabonate (GSK 189075) is converted into remogliflozin in vivo, and is suggested for the treatment of type II diabetes. Uses: The treatment of type ii diabetes. Synonyms: Remogliflozin A; Remogliflozin - GSK189074; GSK-189074; GSK 189074. (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[5-methyl-1-propan-2-yl-4-[(4-propan-2-yloxyphenyl)methyl]pyrazol-3-yl]oxyoxane-3,4,5-triol. Grades: 99%. CAS No. 329045-45-6. Molecular formula: C23H34N2O7. Mole weight: 450.53.
Remogliflozin etabonate
Remogliflozin etabonat, pro-drug of remogliflozin, is a SGLT2 inhibitor under development for the treatment of type 2 diabetes. Remogliflozin etabonate is a pro-drug of remogliflozin, inhibits the sodium-glucose transport proteins (SGLT), which are responsible for glucose reabsorption in the kidney. Uses: Sglt2 inhibitor. Synonyms: GSK189075A; GSK-189075A; GSK 189075A; GSK189075; GSK-189075; GSK 189075; Remogliflozin etabonate.beta-D-Glucopyranoside, 5-methyl-4-((4-(1-methylethoxy)phenyl)methyl)-1-(1-methylethyl)-1H-pyrazol-3-yl, 6-(ethyl carbonate). Grades: ≥98%. CAS No. 442201-24-3. Molecular formula: C26H38N2O9. Mole weight: 522.59.
Remogliflozin etabonate
Remogliflozin etabonate (GSK189075) is an orally active, selective and low-affinity sodium glucose cotransporter (SGLT2) inhibitor with K i values of 1.95 μM, 2.14 μM, 43.1 μM, 8.57 μM for hSGLT2, rSGLT2, hSGLT1, rSGLT1, respectively. Remogliflozin etabonate is a proagent based on benzylpyrazole glucoside and is metabolized to its active form, Remogliflozin, in the body. Remogliflozin etabonate exhibits antidiabetic efficacy in rodent models [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK189075. CAS No. 442201-24-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14945.
Remoxipride hydrochloride
Remoxipride hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 73220-03-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
REMOXIPRIDE HYDROCHLORIDE
Remoxipride is a selective dopamine D2 receptor antagonist. It shows selectivity over D3 and D4 receptors with Ki values are ~ 300nM for D2 receptor, ~ 1600nM for D3 receptor and ~ 2800 nM for D4 receptor. Remoxipride shows antipsychotic activity in vivo with no extrapyramidal side effects. In Jul 1995, treatment for Psychotic disorders in USA was discontinued. Uses: Psychotic disorders. Synonyms: Remoxipride Hydrochloride; Remoxipride HCl; Roxiam; A 33547 hydrochloride; UNII-QS4S72U30K; QS4S72U30K; Remoxipride Hydrochloride Anhydrous ; Remoxipride Monohydrochloride; Remoxipride Monohydrochloride Monohydrate; Remoxipride Monohydrochloride;3-bromo-N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2,6-dimethoxybenzamide;hydrochloride. Grades: 98%. CAS No. 73220-03-8. Molecular formula: C16H24BrClN2O3. Mole weight: 407.73.
Remternetug
Remternetug is a human immunoglobulin G1-kappa, anti-APP (amyloid beta A4 precursor protein) Aβ42 N3pGlu peptide monoclonal antibody. Remternetug recognizes a pyroglutamated form of A&beta. Remternetug results in rapid and robust amyloid plaque reduction. Remternetug can be used for Alzheimer's disease research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: LY3372993. CAS No. 2571940-41-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990078.
renalase
Requires FAD. Renalase, previously thought to be a hormone, is a flavoprotein secreted into the blood by the kidney that oxidizes the 1,2-dihydro- and 1,6-dihydro- isomeric forms of β-NAD(P)H back to β-NAD(P)+. These isomeric forms, generated by nonspecific reduction of β-NAD(P)+ or by tautomerization of β-NAD(P)H, are potent inhibitors of primary metabolism dehydrogenases and pose a threat to normal respiration. Group: Enzymes. Synonyms: αNAD(P)H oxidase/anomerase (incorrect); NAD(P)H:oxygen oxidoreductase (H2O2-forming, epimerising) (incorrect). Enzyme Commission Number: EC 1.6.3.5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1587; renalase; EC 1.6.3.5; αNAD(P)H oxidase/anomerase (incorrect); NAD(P)H:oxygen oxidoreductase (H2O2-forming, epimerising) (incorrect). Cat No: EXWM-1587.
Rencofilstat
Rencofilstat (CRV431) is a pan-cyclophilin inhibitor with IC 50 values of 2.5 nM, 3.1 nM, 2.8 nM, 7.3 nM for Cyp A, CypB, Cyp D and Cyp G, respectively. Rencofilstat reduces fibrosis and tumor growth in models of chronic liver disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CRV431. CAS No. 1383420-08-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-135644.
rengyoside A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 101489-32-1. Molecular formula: C14H26O8. Mole weight: 322.35. Catalog: APB101489321.
Renilla-luciferin 2-monooxygenase
From the soft coral coelenterate Renilla reniformis. The luciferin is bound to a luciferin-binding protein (BP-LH2). The bioluminescent reaction between the luciferin complex, luciferase and oxygen is triggered by calcium ions. In vivo, the excited state luciferin-luciferase complex undergoes the process of nonradiative energy transfer to an accessory protein, Renilla green fluorescent protein, which results in green bioluminescence. In vitro, Renilla luciferase emits blue light in the absence of any green fluorescent protein. Group: Enzymes. Synonyms: Renilla-type luciferase; aequorin; luciferase (Renilla luciferin). Enzyme Commission Number: EC 1.13.12.5. CAS No. 61869-41-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0618; Renilla-luciferin 2-monooxygenase; EC 1.13.12.5; 61869-41-8; Renilla-type luciferase; aequorin; luciferase (Renilla luciferin). Cat No: EXWM-0618.
Renilla-luciferin sulfotransferase
The product may be identical with Watasenia luciferin. Group: Enzymes. Synonyms: luciferin sulfotransferase; luciferin sulfokinase; luciferin sulfokinase (3'-phosphoadenylyl sulfate:luciferin sulfotransferase). Enzyme Commission Number: EC 2.8.2.10. CAS No. 37278-33-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3369; Renilla-luciferin sulfotransferase; EC 2.8.2.10; 37278-33-4; luciferin sulfotransferase; luciferin sulfokinase; luciferin sulfokinase (3'-phosphoadenylyl sulfate:luciferin sulfotransferase). Cat No: EXWM-3369.
renin
Formed from prorenin in plasma and kidney. In peptidase family A1 (pepsin A family). Group: Enzymes. Synonyms: angiotensin-forming enzyme; angiotensinogenase. Enzyme Commission Number: EC 3.4.23.15. CAS No. 9015-94-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4252; renin; EC 3.4.23.15; 9015-94-5; angiotensin-forming enzyme; angiotensinogenase. Cat No: EXWM-4252.
Renin from Human, Recombinant
Renin, also known as an angiotensinogenase, is an enzyme that participates in the body's renin-angiotensin aldosterone system (RAAS)--also known as the renin-angiotensin-aldosterone axis--that mediates extracellular volume (i.e., that of the blood plasma, lymph and interstitial fluid), and arterial vasoconstriction. Thus, it regulates the body's mean arterial blood pressure. Renin is often improperly referred to as a hormone even though it has no peripheral receptors and rather has an enzymatic activity with which it hydrolyses angiotensinogen to angiotensin I. Group: Enzymes. Synonyms: REN; HNFJ2; Renin; angiotensinogenase; Angiotensin forming enzyme. Enzyme Commission Number: EC 3.4.23.15. CAS No. 9015-94-5. Purity: >90%. Renin. Mole weight: ~52kDa (predicted is 38.3 kDa). Activity: >30U/mg. Stability: Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. Storage: at -20°C. Form: Lyophilized. In 25mM MES buffer containing 150mM NaCl. Source: HEK cells, Mature Renin (aa 67-406) is fused at the N-terminus to a FLAG-tag. Active form, does not contain prorenin peptide (aa 1-66). Species: Human. REN; HNFJ2; Renin; angiotensinogenase; Angiotensin forming enzyme. Cat No: NATE-1951.