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| Product | Description | |
|---|---|---|
| RK-33 | RK-33 is a first-in-class inhibitor of DDX3. It causes G1 cell cycle arrest, induces apoptosis, and promotes radiation sensitization in DDX3-overexpressing cells, which has therapeutic use in cancers. Synonyms: RK 33; RK33. CAS No. 1070773-09-9. Molecular formula: C23H20N6O3. Mole weight: 428.44. |  |
| RK-397 | RK-397 is a macrolide antibiotic produced by Streptomyces sp. 87-397. It is cytotoxic against human leukemia HL-60 and K-562 cells at a concentration of 50 μg/mL. It induces bleb-formation on K-562 cells at the concentrations over 0.05 μg/mL. Synonyms: RK 397; RK397; 14-demethyl-mycoticin; 14-demethylmycoticina. CAS No. 154396-73-3. Molecular formula: C35H56O10. Mole weight: 636.8. | |
| RK-682 | RK-682 is the inhibitor for protein tyrosine phosphatase ( PTPase ), heparanase , phospholipase A2 and HIV-1 protease. RK-682 inhibits the dephosphorylation of CD45 ( IC 50 is 54 μM) and VHR ( IC 50 is 2.0 μM), and thereby inhibits the ERK signaling pathway. RK-682 inhibits the cell viability of cancer cell MGH-U3, T24 and UROtsa with IC 50 s of 78.2, 43.2 and 145 nM, respectively, arrests the cell cycle at G1/S phase, inhibits the cell migration and autophagy in MGH-U3 and T24 [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 150627-37-5. Pack Sizes: 200 μg. Product ID: HY-135564A. |  |
| RK-682 calcium salt | It is a dimeric calcium complex of the major analogue of tetronic acid complex isolated from streptomyces. It inhibits protein tyrosine phosphatases, phospoholipase A2, heparinase and HIV-1 protease. Synonyms: TAN 1364B; CI 010; Calcium bis[(R)-2-oxo-3-hexadecanoyl-5-(hydroxymethyl)-2,5-dihydrofuran-4-olate]; (5R)-4-hydroxy-5-(hydroxymethyl)-3-(1-oxohexadecyl)-2(5H)-furanone, calcium salt (2:1); RK-682 calcium salt (2:1). Grades: >95% by HPLC. CAS No. 332131-32-5. Molecular formula: C42H70CaO10. Mole weight: 775.09. | |
| RKI-1313 | RKI-1313 is a negative control of RKI-1447, which is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activity. Synonyms: RKI-1313; RKI 1313; RKI1313. 1-(3-Methoxybenzyl)-3-(4-(pyridin-4-yl)thiazol-2-yl)urea. CAS No. 1342276-76-9. Molecular formula: C17H16N4O2S. Mole weight: 340.401. | |
| RKI1447 | RKI1447 Inhibitor. Uses: Scientific use. Product Category: T1898. CAS No. 1342278-01-6. |  |
| RKI-1447 | RKI-1447 is a potent Rho-associated kinase (ROCK) inhibitor with IC50 values of 14.5 and 6.2 nM for ROCK1 and ROCK2 respectively. It exhibits significant anti-invasive and antitumor activity in breast cancer. In combination with fasudil, it was shown to induce differentiation of mESCs and hESCs to endoderm via ROCK inhibition. Synonyms: RKI 1447; 1-(3-Hydroxybenzyl)-3-(4-(pyridin-4-yl)thiazol-2-yl)urea. Grades: >98%. CAS No. 1342278-01-6. Molecular formula: C16H14N4O2S. Mole weight: 326.374. | |
| RKI-1447 | RKI-1447 is a potent small molecule inhibitor of ROCK1 and ROCK2 with IC 50 values of 14.5 nM and 6.2 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1342278-01-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15755. | |
| RKI 1447 dihydrochloride | RKI 1447 is a potent small molecule inhibitor of ROCK1 and ROCK2 with IC50 values of 14.5 nM and 6.2 nM, respectively. It suppresses phosphorylation of ROCK substrates MLC-2 and MYPT-1 in human cancer cells, but has no effect on the phosphorylation levels of Akt, MEK, and S6 kinase. Furthermore, it can prevent ROCK-mediated migration, invasion, and anchorage-independent growth of MDA-MB-231 breast cancer cells (IC50 = 709 nM). Synonyms: RKI 1447 dihydrochloride; RKI1447 dihydrochloride; RKI-1447 dihydrochloride; N-[(3-Hydroxyphenyl)methyl]-N'-[4-(4-pyridinyl)-2-thiazolyl]urea dihydrochloride; RKI 1447 2Hcl. Grades: ≥99% by HPLC. Molecular formula: C16H14N4O2S.2HCl. Mole weight: 399.29. | |
| RKI 1447 dihydrochloride | RKI 1447 dihydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| RKI-1447 dihydrochloride | RKI 1447 dihydrochloride is a potent and selective ROCK inhibitor with IC 50 s of 14.5 and 6.2 nM for ROCK1 and ROCK2 , respectively [1]. RKI 1447 dihydrochloride suppresses colorectal carcinoma cell growth and promotes apoptosis [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1782109-09-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110339. | |
| RKS-262 | RKS262 is a specific cyclin/CDK inhibitor. RKS262 was identified by structural optimization of Nifurtimox which is currently undergoing phase II clinical trials to treat high-risk neuroblastoma. In a NCI(60) cell-line assay RKS262 exhibited significant cytotoxicity in ovarian cancer cells and a variety of other cell lines exceeding effects of commercial drugs such as cisplatin, 5-FU, cyclophosphamide or sapacitabine. Various leukemia cell-lines were most sensitive while several non-small cell lung cancer cell lines and few cell lines from other tissues were relatively resistant to RKS262 treatment. Synonyms: RKS-262; RKS 262; RKS-262. CAS No. 1041469-97-9. Molecular formula: C15H14BrClN2O4S. Mole weight: 433.70. | |
| RL71 | RL71 is a curcuminoid anticancer agent that exhibits potent cytotoxicity against a variety of ER-negative breast cancer cells. RL71 (1 μM) induces cell cycle arrest in the G2/M phase and induces apoptosis in SKBr3 cells. RL7 also decreases HER2/neu phosphorylation and increases p27. RL71 also significantly reduced the phosphorylation of Akt and transiently increased the stress kinases JNK1/2 and p38 MAPK. Furthermore, RL71 exhibited anti-angiogenic potential in vitro, inhibiting the migration of HUVEC cells and the ability of these cells to form tubular networks [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1195795-93-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121605. | |
| R)-(+)-Lactamide | 25g Pack Size. Group: Building Blocks, Chiral Compounds, Organics. Formula: C3H7NO2. CAS No. 598-81-2. Prepack ID 22922574-25g. Molecular Weight 89.09. See USA prepack pricing. |  |
| R-Laropiprant | Synonyms: R-[4-(4-Chloro-benzyl)-7-fluoro-5-methanesulfonyl-1,2,3,3a,4,8b-hexahydro-cyclopenta[b]indol-3-yl]-acetic acid. Grades: > 95%. Molecular formula: C21H19ClFNO4S. Mole weight: 435.91. | |
| R-Lercanidipine Hydrochloride (R-1,4-Dihydro-2,6-dimethyl-4-(3-nittrophenyl)-3,5-pyridinedicarboxylic Acid 2-[ (3, 3-Diphenylpropyl) methylamino]-1, 1-dimethylethyl Methyl Ester Hydrochloride) | A dihydropyridine calcium channel blocker. Group: Biochemicals. Alternative Names: R-1,4-Dihydro-2,6-dimethyl-4-(3-nittrophenyl)-3,5-pyridinedicarboxylic Acid 2-[ (3, 3-Diphenylpropyl) methylamino]-1, 1-dimethylethyl Methyl Ester Hydrochloride. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| R-Licarbazepine | (R)-10-Monohydroxy-10,11-dihydro Carbamazepine is the metabolite of Oxcarbazepine (OXC) and Eslicarbazepine acetate, (BIA 2-093, ESL), novel central nervous system drugs. ee=98% [α]d=-193 (C=1, pyridine). Synonyms: (10R)-10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide; R-(-)-10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide; (R)-Licarbazepine; CGP 13698. Grades: > 95%. CAS No. 104746-03-4. Molecular formula: C15H14N2O2. Mole weight: 254.29. | |
| R-linalool synthase | Geranyl diphosphate cannot be replaced by isopentenyl diphosphate, dimethylallyl diphosphate, farnesyl diphosphate or geranylgeranyl diphosphate as substrate. Requires Mg2+ or Mn2+ for activity. Unlike many other monoterpene synthases, only a single product, (3R)-linalool, is formed. Group: Enzymes. Synonyms: (3R)-linalool synthase; (-)-3R-linalool synthase. Enzyme Commission Number: EC 4.2.3.26. CAS No. 254993-26-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5183; R-linalool synthase; EC 4.2.3.26; 254993-26-5; (3R)-linalool synthase; (-)-3R-linalool synthase. Cat No: EXWM-5183. |  |
| RLLFT-NH | RLLFT-NH is a reversed amino acid sequence control peptide for TFLLR-NH2. TFLLR-NH2 is a peptide derived from the protease-activated receptor-1 (PAR1) that acts as a PAR1 selective agonist (EC50 = 1.9 μM). Synonyms: RLLFT. CAS No. 447408-68-6. Molecular formula: C31H53N9O6. Mole weight: 647.82. | |
| RLLFT-NH2 | RLLFT-NH2. Group: Biochemicals. Grades: Purified. CAS No. 447408-68-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| RLY-2608 | RLY-2608 is an orally active first-in-class allosteric mutant-selective inhibitor of PI3Ka with anti-tumor activity. RLY-2608 inhibits tumor growth in PIK3CA-mutant xenograft mice models with minimal impact on insulin [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2733573-94-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153306. | |
| RMAD-5 | RMAD-5 is an antibacterial peptide isolated from Macaca mulatta (Rhesus monkey). It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Neutrophil defensin 5; Arg-Thr-Cys-Arg-Cys-Arg-Phe-Gly-Arg-Cys-Phe-Arg-Arg-Glu-Ser-Tyr-Ser-Gly-Ser-Cys-Asn-Ile-Asn-Gly-Arg-Ile-Phe-Ser-Leu-Cys-Cys-Arg. Molecular formula: C155H246N58O43S6. Mole weight: 3802.35. | |
| RMAD-7 | RMAD-7 is an antibacterial peptide isolated from Macaca mulatta (Rhesus monkey). It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Neutrophil defensin 7; Arg-Thr-Cys-Arg-Cys-Arg-Phe-Gly-Arg-Cys-Phe-Arg-Arg-Glu-Ser-Tyr-Ser-Gly-Ser-Cys-Asn-Ile-Asn-Gly-Arg-Ile-Ser-Ser-Leu-Cys-Cys-Ar. Molecular formula: C149H242N58O44S6. Mole weight: 3742.26. | |
| R-(-)-Manidipine | R-(-)-Manidipine. Group: Biochemicals. Alternative Names: (4R)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-[4-(diphenylmethyl)-1-piperazinyl]ethyl methyl ester; (-)-Manidipine. Grades: Highly Purified. CAS No. 133082-19-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C35H38N4O6. US Biological Life Sciences. | Worldwide |
| R-(-)-Manidipine | R-(-)-Manidipine is the (R)-Manidipine enantiomer. It is a dihydropyridine calcium channel blocker. Synonyms: (4R)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 2-[4-(Diphenylmethyl)-1-piperazinyl]ethyl Methyl Ester; (-)-Manidipine. Grades: > 95%. CAS No. 133082-19-6. Molecular formula: C35H38N4O6. Mole weight: 610.7. | |
| RMC-4550 | RMC-4550 is a potent and selective SHP-2 inhibitor with IC50 value of 1.55 nM. It inhibits RAS/MAPK signaling in cancer cell lines with Class 3 BRAF mutations. Synonyms: RMC 4550; RMC4550. CAS No. 2172651-73-7. Molecular formula: C21H26Cl2N4O2. Mole weight: 437.36. | |
| RMC-5552 | RMC-5552 is a potent and selective mTORC1 inhibitor. RMC-5552 inhibits phosphorylation of mTORC1 pS6K and p4EBP1 with IC 50 s of 0.14 nM and 0.48 nM, respectively. RMC-5552 shows much lower pAKT inhibition (IC 50 of 19 nM), resulting in mTORC1/mTORC2 selectivity approaching 40-fold. RMC-5552 has anti-cancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2382768-62-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-132168. | |
| RMC-6236 | RMC-6236 (Compound A122) is a potent RAS(ON) MULTI inhibitor. RMC-6236 can be used in lung adenocarcinoma research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RAS-IN-2. CAS No. 2765081-21-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148439. | |
| RMC-7977 | RMC-7977 is an orally active triple-complex RAS inhibitor that can simultaneously bind to cyclophilin A (CYPA) (K d = 195 nM) and KRAS (G12V) (K d = 292 μM). It exhibits broad-spectrum inhibitory activity against KRAS, NRAS, and HRAS proteins and their various wild-type and mutant variants. RMC-7977 induces apoptosis by inhibiting the phosphorylation of ERK , CRAF , and RSK , as well as increasing PARP cleavage. This leads to tumor regression, reduces resistance in KRAS G12C cancer models, and demonstrates good tolerability across various RAS cancer models [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2765082-12-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-156498. | |
| r-(-)-Mecamylamine hydrochloride | Heterocyclic Organic Compound. Alternative Names: (1S,2R,4R)-. CAS No. 107596-31-6. Molecular formula: C11H22ClN. Mole weight: 203.75. Catalog: ACM107596316. |  |
| R-(-)-Mecamylamine Hydrochloride | The R-(+) enantiomer of Mecamylamine , a noncompetitive neuronal nicotinic receptor modulator. Group: Biochemicals. Alternative Names: (1S,2R,4R)-. Grades: Highly Purified. CAS No. 107596-31-6. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| R-Mevalonic Acid | R-Mevalonic Acid, can stimulate leukemic cells from some patients with B cell chronic lymphocytic leukemia (CLL) to enter the cell cycle in vitro and to synthesize DNA. Group: Biochemicals. Grades: Highly Purified. CAS No. 17817-88-8. Pack Sizes: 10mg, 100mg. Molecular Formula: C6H12O4, Molecular Weight: 148.16. US Biological Life Sciences. | Worldwide |
| R-Mevalonic Acid, Lithium Salt | Mevalonic acid is an intermediate in the mevalonate pathway, producing terpenes and steroids. This function provides treatment options metabolic disorders, R-mevalonate accumulates in patients with the autosomal recessively inherited mevalonic acidurias, an inborn error of cholesterol and nonsterol isoprene biosynthesis. Group: Biochemicals. Alternative Names: Lithium (R)-3,5-dihydroxy-3-methylpentanoate, Lithium (R)-3,5-dihydroxy-3-methylvalerate, R-MVA-Li. Grades: Highly Purified. CAS No. 1255502-07-8. Pack Sizes: 10mg. Molecular Formula: C6H11LiO4, Molecular Weight: 154.09. US Biological Life Sciences. | Worldwide |
| R-(-)-Mexiletine hydrochloride | R-(-)-Mexiletine hydrochloride. Group: Biochemicals. Alternative Names: (2R)-1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride; (-)-(R)-Mexiletine hydrochloride; (-)-Mexiletine hydrochloride. Grades: Highly Purified. CAS No. 81771-86-0. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C11H18ClNO. US Biological Life Sciences. | Worldwide |
| R-Mirtazapine | R-Mirtazapine is an enantiomer of Mirtazapine, an antidepressant. R-Mirtazapine showed antinociceptive effects in acute thermal nociception, whereas S-Mirtazapine showed pronociceptive effects. Synonyms: (14bR)-1,2,3,4,10,14b-Hexahydro-2-methyl-pyrazino[2,1-a]pyrido[2,3-c][2]benzazepine; (R)-1,2,3,4,10,14b-Hexahydro-2-methyl-pyrazino[2,1-a]pyrido[2,3-c][2]benzazepine; (-)-Mirtazapine; (R)-6-Azamianserin; (R)-Mirtazapine; (R)-Org 3770; Org 44-19; R-(-)-Mir. Grades: > 95%. CAS No. 61364-37-2. Molecular formula: C17H19N3. Mole weight: 265.35. | |
| RMM 46 | RMM 46 is a reversible covalent inhibitor that exhibits high ligand efficiency and selectivity for MSK/RSK-family kinases. It shows selectivity for RSK2 over NEK2 and PLK1 (IC50s= 12, 530 and 2200 nM, respectively). Synonyms: RMM-46; RMM 46; RMM46; 2-Cyano-N-(2-hydroxy-1,1-dimethylethyl)-3-[3-(3,4,5-trimethoxyphenyl)-1H-indazol-5-yl]-2-propenamide. Grades: ≥98% by HPLC. CAS No. 1307896-46-3. Molecular formula: C24H26N4O5. Mole weight: 450.5. | |
| R-Morinidazole | R-Morinidazole is the R enantiomer of Morinidazole, wich is a novel 5-nitroimidazole antimicrobial drug. It undergoes extensive metabolism in humans via N+-glucuronidation and sulfation. It is used in the treatment of bacterial infections including appendicitis and pelvic inflammatory disease (PID) caused by anaerobic bacteria. Uses: R-morinidazole is used in the treatment of bacterial infections including appendicitis and pelvic inflammatory disease (pid) caused by anaerobic bacteria. Synonyms: (R)-1-(2-Methyl-5-nitro-1H-imidazol-1-yl)-3-morpholinopropan-2-ol;(2R)-1-(2-methyl-5-nitroimidazol-1-yl)-3-morpholin-4-ylpropan-2-ol;Morinidazole R enantiomer. Grades: >98%. CAS No. 898230-59-6. Molecular formula: C11H18N4O4. Mole weight: 270.29. | |
| RN 1734 | RN 1734. Group: Biochemicals. Grades: Purified. CAS No. 946387-07-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| RN-1734 | RN-1734 is selective antagonist of the TRPV4 channel. It completely antagonizes 4αPDD-mediated activation of TRPV4 with comparable, low micromolar IC50values for all three species with IC50 values are 2.3, 3.2 and 5.9 μM for hTRPV4, rTRPV4 and mTRPV4 receptors respectively. It is selective for TRPV4 in a TRP selectivity panel, thus is used as a valuable pharmacological probe for TRPV4 studies. It blocks TRPV4-mediated arteriole vasodilation and increases myogenic tone ex vivo. Uses: Rn-1734 is used as a valuable pharmacological probe for trpv4 studies. Synonyms: RN1734; RN 1734; RN-1734; 2, 4-Dichloro-N-isopropyl-N- (2-isopropylaminoethyl) benzenesulfonamide; 2, 4-Dichloro-N-propan-2-yl-N-[2- (propan-2-ylamino) ethyl]benzenesulfonamide; 2, 4-Dichloro-N- (1-methylethyl) -N-[2-[ (1-methylethyl) amino]ethyl]benzenesulfonamide. Grades: 95%. CAS No. 946387-07-1. Molecular formula: C14H22Cl2N2O2S. Mole weight: 353.31. | |
| Rn 1747 | Heterocyclic Organic Compound. Alternative Names: 4,6-Diaethoxy-2-((Z)-veratryliden)-benzofuran-3-on; RN-1747. CAS No. 102448-59-6. Molecular formula: C17H18CIN3O4S. Mole weight: C17H18CIN3O4S. Purity: 0.96. IUPACName: 4,6-diethoxy-2-((Z)-veratrylidene)-benzofuran-3-one. Catalog: ACM102448596. | |
| RN 1747 | RN 1747, a selective TRPV4 agonist (EC50= 0.77, 4.0 and 4.1 μM for hTRPV4, mTRPV4 and rTRPV4 respectively), represents the first drug-like TRPV4 antagonist with selectivity over closely related TRP channels. The activities of these compounds were characterized using two different systems: Ca2+ influx assay with human, mouse and rat TRPV4-expressing HEK293 cells and electrophysiology in hTRPV4-transfected Xenopus oocytes. Importantly, RN-1734 antagonized both ligand-gated activation and hypotonicity-induced opening of TRPV4 in both types of assay. Synonyms: Piperazine, 1-[(4-chloro-2-nitrophenyl)sulfonyl]-4-(phenylmethyl)-; 1-[(4-Chloro-2-nitrophenyl)sulfonyl]-4-(phenylmethyl)piperazine; RN1747; RN-1747; 1-(4-Chloro-2-nitrophenyl)sulfonyl-4-benzylpiperazine. Grades: ≥95%. CAS No. 1024448-59-6. Molecular formula: C17H18ClN3O4S. Mole weight: 395.87. | |
| RN 1747 | RN 1747. Group: Biochemicals. Grades: Purified. CAS No. 1024448-59-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| RN-1747 | Heterocyclic Organic Compound. Alternative Names: 4-CHLORO-2-NITRO-1-((4-BENZYLPIPERAZINYL)SULFONYL)BENZENE, AC1NNFV2, CTK6G7369, ZINC29938125, AG-B-04317, RN-1747, ST50952965, 1-benzyl-4-(4-chloro-2-nitrophenyl)sulfonylpiperazine, 1-(4-Chloro-2-nitrophenyl)sulfonyl-4-benzylpiperazine;, 1-[ (4-Chloro-2-nitrophenyl)sulfonyl]-4- (phenylmethyl)-piperazine, 1024448-59-6. CAS No. 1024448-59-6. Molecular formula: C17H18ClN3O4S. Mole weight: 395.86. Purity: 0.96. IUPACName: 1-benzyl-4-(4-chloro-2-nitrophenyl)sulfonylpiperazine. Canonical SMILES: C1CN (CCN1CC2=CC=CC=C2)S (=O) (=O)C3=C (C=C (C=C3)Cl)[N+] (=O)[O-]. Catalog: ACM1024448596. | |
| RN-18 | RN-18, a selective inhibitor of virion infectivity factor (Vif) APOBEC interactions and HIV-1 replication (IC50= 6 μM in nonpermissive H9 cells), antagonizes Vif function and inhibits HIV-1 replication only in the presence of A3G. Synonyms: RN-18; RN 18; RN18; N-(2-methoxyphenyl)-2-(4-nitrophenyl)sulfanylbenzamide; 2-(4-Nitrophenylthio)-N-(2-methoxyphenyl)benzamide; AC1LQ42R; Ambcb6776439. Grades: 99.37%. CAS No. 431980-38-0. Molecular formula: C20H16N2O4S. Mole weight: 380.42. | |
| RN 1 dihydrochloride | RN 1 dihydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| RN 1 dihydrochloride | RN 1 is a potent lysine specific demethylase 1 (LSD1) inhibitor (IC50 = 70 nM), which exhibits selectivity for LSD1 over MAO-A and MAO-B (IC50= 0.51 and 2.79 μM for MAO-A and MAO-B, respectively). It blocks long-term but not short-term memory in mice following intraperitoneal administration. RN-1 also induces cytotoxicity in ovarian cancer cell lines and induces fetal hemoglobin synthesis while reducing disease pathology in sickle cell mice. Synonyms: RN 1 dihydrochloride; RN-1 dihydrochloride; RN1 dihydrochloride; 1- (4-methyl-1-piperazinyl) -2-[[ (1R*, 2S*) -2-[4-phenylmethoxy) phenyl]cyclopropyl]amino]ethanone dihydrochloride; RN-1, monohydrochloride; RN-1 2HCl. Grades: ≥97% by HPLC. CAS No. 1781835-13-9. Molecular formula: C23H29N3O2.2HCl. Mole weight: 452.42. | |
| RN-1 dihydrochloride | RN-1 dihydrochloride is a potent, brain-penetrant, irreversible and selective lysine-specific demethylase 1 (LSD1) inhibitor with an IC 50 of 70 nM. RN-1 dihydrochloride exhibits selectivity for LSD1 over MAO-A and MAO-B with IC 50 values of 0.51 μM and 2.785 μM respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1781835-13-9. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-110130. | |
| RN2PA_RANPI Ranatuerin-2Pa precursor | RN2PA_RANPI Ranatuerin-2Pa precursor is an antibacterial peptide isolated from Rana pipiens. Synonyms: Gly-Phe-Leu-Ser-Thr-Val-Lys-Asn-Leu-Ala-Thr-Asn-Val-Ala-Gly-Thr-Val-Ile-Asp-Thr-Ile-Lys-Cys-Lys-Val-Thr-Gly-Gly-Cys. | |
| RN486 | RN486 is a reversible Bruton's tyrosine kinase (Btk) inhibitor with IC50 value of 4.0 nM. Synonyms: RN486; RN-486; RN 486. Grades: >98%. CAS No. 1242156-23-5. Molecular formula: C35H35FN6O3. Mole weight: 606.69. | |
| RN983 | RN983 is a selective BTK enzyme inhibitor. It inhibits IgG production in B-cells with an IC50 value of 2.5?±?0.7?nM and PGD2 production from mast cells with an IC50 value of 8.3?±?1.1?nM. RN983 showed similar activities in the allergic mouse model of asthma. RN983 may be effective as a stand-alone asthma therapy or used in combination with inhaled steroids and β-agonists in severe asthmatics. Uses: Asthma. Synonyms: RN983; RN-983; RN 983. 6-(tert-butyl)-8-fluoro-2-(3-(hydroxymethyl)-4-(1-methyl-5-((5-(1-methylpiperidin-4-yl)pyridin-2-yl)amino)-6-oxo-1,6-dihydropyridazin-3-yl)pyridin-2-yl)phthalazin-1(2H)-one. Grades: 98%. CAS No. 1423129-83-2. Molecular formula: C34H37FN8O3. Mole weight: 624.72. | |
| RN-9893 | RN-9893 is a potent and selective TRPV4 receptor antagonist with IC 50 values of 320, 420 and 660 nM for mouse, human and rat channels, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1803003-68-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-110270. | |
| RN 9893 hydrochloride | RN 9893 is a potent and selective antagonist of the Transient Receptor Potential ion channel TRPV4 (IC50= 320, 420 and 660 nM for mouse, human and rat channels, respectively), with >15-fold selectivity for TRPV4 over TRPV1, TRPV3 and TRPM8, and a panel of 54 other common biological targets. Synonyms: N-[4-[[4-(1-Methylethyl)-1-piperazinyl]sulfonyl]phenyl]-2-nitro-4-(trifluoromethyl)benzamide hydrochloride; RN9893 HCl; RN-9893 HCl; RN 9893 HCl; RN9893 Hydrochloride; RN-9893 Hydrochloride; RN 9893 Hydrochloride. Grades: ≥99% by HPLC. CAS No. 1803003-68-0. Molecular formula: C21H23F3N4O5S.HCl. Mole weight: 536.95. | |
| RNA 3'-terminal-phosphate cyclase (ATP) | Adenosine 5'-(γ-thio)triphosphate can act instead of ATP. cf. EC 6.5.1.5, RNA-3'-phosphate cyclase (GTP). Group: Enzymes. Synonyms: RNA cyclase (ambiguous); RNA-3'-phosphate cyclase (ambiguous). Enzyme Commission Number: EC 6.5.1.4. CAS No. 85638-41-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5823; RNA 3'-terminal-phosphate cyclase (ATP); EC 6.5.1.4; 85638-41-1; RNA cyclase (ambiguous); RNA-3'-phosphate cyclase (ambiguous). Cat No: EXWM-5823. | |
| RNA 3'-terminal-phosphate cyclase (GTP) | The enzyme from the archaeon Pyrococcus furiosus is activated by Mg2+. cf. EC 6.5.1.4, RNA-3'-phosphate cyclase (ATP). Group: Enzymes. Synonyms: Pf-Rtc; RNA-3'-phosphate cyclase (GTP). Enzyme Commission Number: EC 6.5.1.5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5824; RNA 3'-terminal-phosphate cyclase (GTP); EC 6.5.1.5; Pf-Rtc; RNA-3'-phosphate cyclase (GTP). Cat No: EXWM-5824. | |
| RNA-directed DNA polymerase | Catalyses RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time. Cannot initiate a chain de novo. Requires an RNA or DNA primer. DNA can also serve as template. See also EC 2.7.7.7 DNA-directed DNA polymerase. Group: Enzymes. Synonyms: DNA nucleotidyltransferase (RNA-directed); reverse transcriptase; revertase; RNA-dependent deoxyribonucleate nucleotidyltransferase; RNA revertase; RNA-dependent DNA polymerase; RNA-instructed DNA polymerase; RT. Enzyme Commission Number: EC 2.7.7.49. CAS No. 9068-38-6. RT. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3261; RNA-directed DNA polymerase; EC 2.7.7.49; 9068-38-6; DNA nucleotidyltransferase (RNA-directed); reverse transcriptase; revertase; RNA-dependent deoxyribonucleate nucleotidyltransferase; RNA revertase; RNA-dependent DNA polymerase; RNA-instructed DNA polymerase; RT. Cat No: EXWM-3261. | |
| RNA-directed RNA polymerase | Catalyses RNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time. Can initiate a chain de novo. See also EC 2.7.7.6 DNA-directed RNA polymerase. Group: Enzymes. Synonyms: RNA nucleotidyltransferase (RNA-directed); RNA nucleotidyltransferase (RNA-directed); RNA-dependent ribonucleate nucleotidyltransferase; 3D polymerase; PB1 proteins; PB2 proteins; phage f2 replicase; polymerase L; Q-β replicase; phage f2 replicase; ribonuclei. Enzyme Commission Number: EC 2.7.7.48. CAS No. 9026-28-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3260; RNA-directed RNA polymerase; EC 2.7.7.48; 9026-28-2; RNA nucleotidyltransferase (RNA-directed); RNA nucleotidyltransferase (RNA-directed); RNA-dependent ribonucleate nucleotidyltransferase; 3D polymerase; PB1 proteins; PB2 proteins; phage f2 replicase; polymerase L; Q-β replicase; phage f2 replicase; ribonucleic acid replicase; ribonucleic acid-dependent ribonucleate nucleotidyltransferase; ribonucleic acid-dependent ribonucleic acid polymerase; ribonucleic replicase; ribonucleic synthetase; RNA replicase; RNA synthetase; RNA transcriptase; RNA-dependent ribonucleate nucleotidyltransferase; RDRP; RNA-dependent RNA polymerase; RNA-dependent RNA replicase; transcriptase. Cat No: EXWM-3260. | |
| r-(+)-Naftopidil | Heterocyclic Organic Compound. CAS No. 127931-15-1. Catalog: ACM127931151. | |
| RNA helicase | RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. Some helicases unwind DNA as well as RNA. May be identical with EC 3.6.4.12 (DNA helicase). Group: Enzymes. Synonyms: CSFV NS3 helicase; DBP2; DbpA; DDX17; DDX25; DDX3; DDX3X; DDX3Y; DDX4; DDX5; DEAD-box protein DED1; DEAD-box RNA helicase; DEAH-box protein 2; DEAH-box RNA helicase; DED1; Dex(H/D) RNA helicase; EhDEAD1; EhDEAD1 RNA helicase; eIF4A helicase; KOKV helicase; Mtr4p; nonstructural protein 3 helicase; NPH-II; RHA; RNA helicase A; RNA helicase DDX3; RNA helicase Hera; RNA-dependent ATPase; TGBp1 NTPase/helicase domain; VRH1; GRTH/DDX25. Enzyme Commission Number: EC 3.6.4.13. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4703; RNA helicase; EC 3.6.4.13; CSFV NS3 helicase; DBP2; DbpA; DDX17; DDX25; DDX3; DDX3X; DDX3Y; DDX4; DDX5; DEAD-box protein DED1; DEAD-box RNA helicase; DEAH-box protein 2; DEAH-box RNA helicase; DED1; Dex(H/D) RNA helicase; EhDEAD1; EhDEAD1 RNA helicase; eIF4A helicase; KOKV helicase; Mtr4p; nonstructural protein 3 helicase; NPH-II; RHA; RNA helicase A; RNA helicase DDX3; RNA helicase Hera; RNA-dependent ATPase; TGBp1 NTPase/helicase domain; VRH1; GRTH/DDX25. Cat No: EXWM-4703. | |
| RNAIII-inhibiting peptide | RNAIII-inhibiting peptide, a potent staphylococcus aureus inhibitor, is effective against cellulitis, keratitis, septic arthritis, osteomyelitis and mastitis, among other diseases. Synonyms: H-Tyr-Ser-Pro-Trp-Thr-Asn-Phe-NH2; L-tyrosyl-L-seryl-L-prolyl-L-tryptophyl-L-threonyl-L-asparagyl-L-phenylalaninamide; L-Phenylalaninamide, L-tyrosyl-L-seryl-L-prolyl-L-tryptophyl-L-threonyl-L-asparaginyl-; L-Tyrosyl-L-seryl-L-prolyl-L-tryptophyl-L-threonyl-L-asparaginyl-L-phenylalaninamide; RNAIII-inhibiting peptide (synthetic). Grades: ≥95%. CAS No. 661485-29-6. Molecular formula: C45H56N10O11. Mole weight: 912.99. | |
| RNA ligase (ATP) | The enzyme catalyses the ligation of RNA strands with 3'-hydroxyl and 5'-phosphate termini, forming a phosphodiester and sealing certain types of single-strand breaks in RNA. Catalysis occurs by a three-step mechanism, starting with the activation of the enzyme by ATP, forming a phosphoramide bond between adenylate and a lysine residue. The adenylate group is then transferred to the 5'-phosphate terminus of the substrate, forming the capped structure 5'-(5'-diphosphoadenosine)-[RNA]. Finally, the enzyme catalyses a nucleophilic attack of the 3'-OH terminus on the capped terminus, which results in formation of the phosphodiester bond and release of the adenylate. Group: Enzymes. Synonyms: polyribonucleotide synthase (ATP); RNA ligase; polyribonucleotide ligase; ribonucleic ligase; poly(ribonucleotide): poly(ribonucleotide) ligase (AMP-forming). Enzyme Commission Number: EC 6.5.1.3. CAS No. 37353-39-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5822; RNA ligase (ATP); EC 6.5.1.3; 37353-39-2; polyribonucleotide synthase (ATP); RNA ligase; polyribonucleotide ligase; ribonucleic ligase; poly(ribonucleotide): poly(ribonucleotide) ligase (AMP-forming). Cat No: EXWM-5822. | |
| RNA Ligase T4, 10-20u/ul, 10X Buffer | RNA Ligase T4, 10-20u/ul, 10X Buffer. Group: Molecular Biology. Alternative Names: Supplied with 10x Reaction Buffer, ATP and BSA Solutions. Grades: Molecular Biology Grade. Pack Sizes: 200ul. US Biological Life Sciences. | Worldwide |
| RNA Ligase T4, 10-20u/ul, ATP Buffer | RNA Ligase T4, 10-20u/ul, ATP Buffer. Group: Molecular Biology. Alternative Names: Supplied with 10x Reaction Buffer, ATP and BSA Solutions. Grades: Molecular Biology Grade. Pack Sizes: 200ul. US Biological Life Sciences. | Worldwide |
| RNA Ligase T4, 10-20u/ul, BSA Buffer | RNA Ligase T4, 10-20u/ul, BSA Buffer. Group: Molecular Biology. Alternative Names: Supplied with 10x Reaction Buffer, ATP and BSA Solutions. Grades: Molecular Biology Grade. Pack Sizes: 200ul. US Biological Life Sciences. | Worldwide |
| R-Naproxen | A metabolite of Naproxen, which is a non-selective COX inhibitor. Synonyms: (2R)-2-(6-methoxynaphthalen-2-yl)propanoic acid; (R)-(-)-6-Methoxy-α-methyl-2-naphthaleneacetic acid. Grades: > 95%. CAS No. 23979-41-1. Molecular formula: C14H14O3. Mole weight: 230.27. | |
| RNase A, Bovine pancreas | RNase A, Bovine pancreas (Ribonuclease A) cleaves the 3' end of RNA to pyrimidine and actively cleaves RNA at each pyrimidine residue. RNase A, bovine pancreas catalyzes the hydrolysis of single-stranded RNA in the absence of metal ions or cofactors [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ribonuclease A; EC 4.6.1.18; RNase A. CAS No. 9001-99-4. Pack Sizes: 25 mg; 50 mg. Product ID: HY-129046. | |
| RNase H | RNase H. Ribonuclease h (rnase h) specifically degrades the rna strand in rna-dna hybrids. it does not hydrolyze the phosphodiester bonds within single-stranded and double-stranded dna and rna. this product is purified from e. coli expressing the recombinant rnha gene on a plasmid with 17 kda molecular weight and it can be inactivated by heating at 65°c for 20 minutes. Group: DNA Modifying Enzymes. Purity: 100U; 5*100KU. Storage: Store at -20°C. Cat No: ME-4003. | |
| RNA uridylyltransferase | The enzyme requires an oligoribonucleotide or polyribonucleotide with a free terminal 3'-OH as a primer. Group: Enzymes. Synonyms: terminal uridylyltransferase; TUT. Enzyme Commission Number: EC 2.7.7.52. CAS No. 78519-53-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3265; RNA uridylyltransferase; EC 2.7.7.52; 78519-53-6; terminal uridylyltransferase; TUT. Cat No: EXWM-3265. | |
| R)-(+)-N-Benzyl-1-phenylethylamine | R)-(+)-N-Benzyl-1-phenylethylamine. Group: Biochemicals. Alternative Names: (α R) -α -Methyl-N- (phenylmethyl) benzenemethanamine; (+)-Benzylphenethylamine; (+)-N-Benzyl-1-phenylethylamine; (+)-N-Benzyl-α-phenylethylamine; (R)-(+)-N-Benzyl-α-methylbenzylamine; (R)-Benzyl(α-methylbenzyl)amine; (R)-N-(α-Methylbenzyl)-N-benzylamine; (R)-N-Benzyl-1-phenyl-1-ethylamine; (R)-N-Benzyl-1-phenylethanamine; (R)-N-Benzyl-1-phenylethylamine; (R)-N-Benzyl-N-α-methylbenzylamine; (R)-N-Benzyl-α-methylbenzylamine; (R)-N-Benzyl-α-methylbenzylamine; Benzyl((R)-1-phenylethyl)amine; N-Benzyl((R)-1-phenylethyl)amine; N-Benzyl-(R)-α-methylbenzylamine; N- [ (R) -1-Phenylethyl] benzylamine. Grades: Highly Purified. CAS No. 38235-77-7. Pack Sizes: 1g. Molecular Formula: C15H17N, Molecular Weight: 211.3. US Biological Life Sciences. | Worldwide |
| R-(-)-N-Demethyl Deprenyl | A metabolite of selegiline. Selegiline, also known as L-deprenyl, is a substituted phenethylamine. At normal clinical doses, it is a selective irreversible MAO-B inhibitor used to reduce symptoms in early-stage Parkinson's disease. In larger doses it loses its specificity and also inhibits MAO-A. Uses: Monoamine oxidase inhibitors. Synonyms: (αR)-α-Methyl-N-2-propyn-1-yl-benzeneethanamine; (-)-Desmethylselegiline; (-)-N-Desmethylselegiline; Desmethylselegiline; L-Desmethyldeprenyl; L-Nordeprenyl; N-Desmethylselegiline; Norselegiline. Grades: > 95%. CAS No. 56862-28-3. Molecular formula: C12H15N. Mole weight: 173.25. | |
| R-(-)-N-Demethyl Deprenyl-d5 | 2H Labeled Compounds. CAS No. 1217977-04-2. Molecular formula: C12H10D5N. Mole weight: 178.29. Catalog: ACM1217977042. | |
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