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An impurity of Rocuronium.Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation. Synonyms: 1-[(2β, 3α, 5α, 16β, 17β)-17-(Acetyloxy)-3-hydroxy-2-(1-pyrrolidinyl)androstan-16-yl]-1-(2-propen-1-yl)-pyrrolidinium Bromide. Grades: > 95%. Molecular formula: C32H53N2O3. Br. Mole weight: 593.69.
Rocuronium Bromide Impurity 22
An impurity of Rocuronium.Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation. Grades: > 95%. Molecular formula: C32H51N2O6. Br. Mole weight: 639.67.
Rocuronium EP Impurity A
An impurity of Rocuronium. Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation. Synonyms: 2β-(4-Morpholinyl)-16β-(1-pyrrolidinyl)-5α-androstane-3α,17β-diol 17-Acetate; (2β, 3α, 5α, 16β, 17β)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane-3, 17-diol 17-Acetate; Desallyl Rocuronium. Grades: 99 %. CAS No. 119302-24-8. Molecular formula: C29H48N2O4. Mole weight: 488.72.
Rocuronium EP Impurity C
An impurity of Rocuronium. Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation. Synonyms: 17-Desacetyl Rocuronium Bromide; 1-[(2β, 3α, 5α, 16β, 17β)-3, 17-Dihydroxy-2-(4-morpholinyl)androstan-16-yl]-1-(2-propenyl)pyrrolidinium Bromide. Grades: > 95%. CAS No. 119302-86-2. Molecular formula: C30H51N2O3.Br. Mole weight: 567.65.
Rocuronium EP Impurity E
An impurity of Rocuronium. Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation. Synonyms: 2-Pyrrolidinyl Desmorpholinylrocuronium Bromide; 1-[(2β, 3α, 5α, 16β, 17β)-17-(Acetyloxy)-3-hydroxy-2-(1-pyrrolidinyl)androstan-16-yl]-1-(2-propen-1-yl)-pyrrolidinium Bromide. Grades: > 95%. CAS No. 1190105-65-7. Molecular formula: C32H53N2O3. Br. Mole weight: 593.69.
Rocuronium EP Impurity G
An impurity of Rocuronium. Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation. Synonyms: 2β-(4-Morpholinyl)-16β-(1-pyrrolidinyl)-5α-androstane-3α,17β-diol; (2β, 3α, 5α, 16β, 17β)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstan-3, 17-diol; Desacetyl Desallyl Rocuronium. Grades: 99 %. CAS No. 119302-20-4. Molecular formula: C27H46N2O3. Mole weight: 446.68.
Rocuronium EP Impurity H
An impurity of Rocuronium. Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation. Synonyms: 1,2-Dehydro-3-oxo Rocuronium Bromide; Rocuronium Bromide Impurity 21; 1-[(5α,16β,17β)-17-(Acetyloxy)-2-(4-morpholinyl)-3-oxoandrost-1-en-16-yl]-1-(2-propen-1-yl)-pyrrolidinium Bromide. Grades: > 95%. CAS No. 1190105-67-9. Molecular formula: C32H49N2O4.Br. Mole weight: 605.65.
Rodaplutin
Rodaplutin is a peptidylnucleoside antibiotic produced by Streptomyces sp. Sch 36605. It exhibits anti-inflammatory and moderate antibacterial activity. Synonyms: Sch-36605; Sch 36605. CAS No. 108351-49-1. Molecular formula: C24H39N9O7. Mole weight: 565.6.
Rodatristat
Rodatristat (KAR5417) is a potent tryptophan hydroxylase 1 (TPH1) and TPH2 inhibitor with IC 50 s value of 33 nM and 7 nM, respectively, and shows robust reduction of intestinal serotonin (5-HT) levels in mice [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KAR5417. CAS No. 1673568-73-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-120083.
Rodatristat ethyl
Rodatristat ethyl (KAR5585) is a first-in-class oral tryptophan hydroxylase 1 (TPH1) Inhibitor with nanomolar in vitro potency. Rodatristat ethyl reduces the level of 5-HT and significantly reduces pulmonary arterial hypertension (PAH) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KAR5585. CAS No. 1673571-51-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101124.
Rodatristat ethyl
Rodatristat ethyl is a tryptophan hydroxylase 1 (TPH1) inhibitor, which reduces 5-HT levels and significantly reduces pulmonary hypertension (PAH). Synonyms: KAR5585; KAR-5585. Grades: ≥98% by HPLC. CAS No. 1673571-51-1. Molecular formula: C29H31ClF3N5O3. Mole weight: 590.
R-(-)-O-Desmethyl venlafaxine
R-(-)-O-Desmethyl venlafaxine. Group: Biochemicals. Alternative Names: (R)-(-)-4-[2-(Dimethylamino)-1-(1-hydroxycyclo-hexyl)ethyl]phenol; (-)-O-Desmethylvenlafaxine; (R)-(-)-O-Desmethylvenlafaxine. Grades: Highly Purified. CAS No. 142761-11-3. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C16H25NO2. US Biological Life Sciences.
Worldwide
R-(-)-O-Desmethyl-Venlafaxine
R-(-)-O-Desmethyl-Venlafaxine is a metabolite of Venlafaxine. Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is used as an antidepressant. According to different doses, it effects on serotonergic transmission, noradrenergic systems and dopaminergic neurotransmission. Venlafaxine is commonly used to treat depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms. Synonyms: (R)-(-)-4-[2-(Dimethylamino)-1-(1-hydroxycyclo-hexyl)ethyl]phenol; (-)-O-Desmethylvenlafaxine; (R)-(-)-O-Desmethylvenlafaxine. CAS No. 142761-11-3. Molecular formula: C16H25NO2. Mole weight: 263.38.
Rodol BA
Rodol BA. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Rodol BA. Product Category: Heterocyclic Organic Compound. CAS No. 2543-23-9. Product ID: ACM2543239. Alfa Chemistry ISO 9001:2015 Certified. Categories: Rodel Batocabe.
Rofapitide tetraxetan
Rofapitide tetraxetan (FAP-2286) is a potent and selective FAP-binding peptide with a mean IC 50 value of 2.7 nM for binding to FAP. Rofapitide tetraxetan can be labeled with radionuclides for diagnostic applications. Rofapitide tetraxetan has antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FAP-2286. CAS No. 2581741-18-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-147057.
Rofecoxib
Rofecoxib is a potent, specific and orally active COX-2 inhibitor, with IC 50 s of 26 and 18 nM for human COX-2 in human osteosarcoma cells and Chinese hamster ovary cells, with a 1000-fold selectivity for COX-2 over human COX-1 (IC 50 > 50 μM in U937 cells and > 15 μM in Chinese hamster ovary cells). Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK 966. CAS No. 162011-90-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-17372.
Rofecoxib
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C17H14O4S. CAS No. 162011-90-7. Prepack ID 85601753-1g. Molecular Weight 314.36. See USA prepack pricing.
Rofecoxib
100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C17H14O4S. CAS No. 162011-90-7. Prepack ID 85601753-100mg. Molecular Weight 314.36. See USA prepack pricing.
Rofecoxib
Rofecoxib is a COX-2 inhibitor (IC50s = 26 nM and > 50 μM in human osteosarcoma cells). Uses: Cyclooxygenase 2 inhibitors. Synonyms: MK966; MK966; MK 966; MK0966; MK0966; MK 0966; Rofecoxib; brand name: Vioxx; Ceoxx; Ceeoxx. 4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanone. Grades: > 95%. CAS No. 162011-90-7. Molecular formula: C17H14O4S. Mole weight: 314.4.
R-Ofloxacin
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
?98% (HPLC). Group: Fluorescence/luminescence spectroscopyapi standardsenzyme activators, inhibitors & substratespharmaceutical toxicology. Alternative Names: Daxas, 3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide, BYK 20869, BY 217, Roflumilast,3-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)-benzamide, B 9302-107.
Roflumilast
Roflumilast (APTA-2217) is a selective PDE4 inhibitor with IC 50 s of 0.7, 0.9, 0.7, and 0.2 nM for PDE4A1 , PDEA4 , PDEB1 , and PDEB2 , respectively, without affecting PDE1, PDE2, PDE3 or PDE5 isoenzymes from various cells. Uses: Scientific research. Group: Signaling pathways. Alternative Names: APTA-2217; BYK 20869; B9302-107. CAS No. 162401-32-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15455.
Roflumilast
Selective phosphodiesterase 4 (PDE4) inhibitor. Antiasthmatic; in treatment of chronic obstructive pulmonary disease. Group: Biochemicals. Alternative Names: 3- (Cyclopropylmethoxy) -N- (3, 5-dichloro-4-pyridinyl) -4- (difluoromethoxy) benzamide; B 9302-107; BY 217; BYK 20869. Grades: Highly Purified. CAS No. 162401-32-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg. Molecular Formula: C17H14Cl2F2N2O3, Form: Supplied as a white to off-white. US Biological Life Sciences.
Worldwide
Roflumilast-d3
Roflumilast-d3 is deuterium labeled Roflumilast. Roflumilast is a selective PDE4 inhibitor with IC50s of 0.7, 0.9, 0.7, and 0.2 nM for PDE4A1, PDEA4, PDEB1, and PDEB2, respectively, without affecting PDE1, PDE2, PDE3 or PDE5 isoenzymes from various cells. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-(Cyclopropylmethoxy-d3)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide; B 9302-107-d3; BY 217-d3; BYK 20869-d3. Product Category: Inhibitors. Appearance: Crystallin Solid. CAS No. 1189992-00-4. Molecular formula: C17H11D3Cl2F2N2O3. Mole weight: 406.23. Canonical SMILES: [2H]C1(CC1)C([2H])([2H])OC2=C(C=CC(C(NC3=C(Cl)C=NC=C3Cl)=O)=C2)OC(F)F. Product ID: ACM1189992004. Alfa Chemistry ISO 9001:2015 Certified.
Roflumilast-d4
Labeled selective phosphodiesterase 4(PDE4) inhibitor. Antiasthmatic; in treatment of chronic obstructive pulmonary disease. Group: Biochemicals. Alternative Names: 3- (Cyclopropyl-d4) methoxy-N- (3, 5-dichloro-4-pyridinyl) -4- (difluoromethoxy) benzamide; B 9302-107-d4; BY 217-d4; BYK 20869-d4. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. US Biological Life Sciences.
Worldwide
Roflumilast-D4
Roflumilast-D4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1398065-69-4. Molecular formula: C17H10D4Cl2F2N2O3. Mole weight: 407.23. Catalog: APB1398065694.
Roflumilast Dimer
An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. CAS No. 1352122-37-2. Molecular formula: C29H24Cl2F4N2O6. Mole weight: 643.42.
Roflumilast Impurity 1
An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: 4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast; Roflumilast Impurity A. Grades: > 95%. CAS No. 162401-43-6. Molecular formula: C17H14Cl2F2N2O3. Mole weight: 403.22.
Roflumilast Impurity 10
An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. Molecular formula: C17H16F2N2O3. Mole weight: 334.33.
Roflumilast Impurity 11
An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. Molecular formula: C16H14Cl2N2O3. Mole weight: 353.21.
Roflumilast Impurity 2
An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. Molecular formula: C13H8Cl2F2N2O3. Mole weight: 349.12.
Roflumilast Impurity 3
An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: 3,4-Bis(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)benzamide; 1391052-24-6; 3,4-Di(cyclopropylmethoxy) Roflumilast; BenzaMide, 3,4-bis(cyclopropylMethoxy)-N-(3,5-dichloro-4-pyridinyl)-; C20H20Cl2N2O3; 3,4-bis(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-benzamide; Roflumilast Impurity 3; DTXSID70747612; MFCD23703092; AKOS016012227; DS-6755; AC-28929; CS-0155388; C72553; A886144; A1-04290; 3,4-Bis(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)benzamide. Grades: > 95%. Molecular formula: C20H20Cl2N2O3. Mole weight: 407.29.
Roflumilast Impurity 4
An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. Molecular formula: C14H8Cl2F4N2O3. Mole weight: 399.13.
Roflumilast Impurity 5
An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. Molecular formula: C16H14Cl2N2O3. Mole weight: 353.21.
Roflumilast Impurity 6
An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. Molecular formula: C16H10F2O8. Mole weight: 368.25.
Roflumilast Impurity 7
An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. Molecular formula: C17H14BrClF2N2O3. Mole weight: 447.67.
Roflumilast Impurity 8
An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. Molecular formula: C17H14Cl2F2N2O3. Mole weight: 403.22.
Roflumilast Impurity 9
An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. Molecular formula: C17H14Cl2F2N2O3. Mole weight: 403.22.
Roflumilast Impurity B
One impurity of Roflumilast, which is a PDE4 inhibitor and has been found to be effective as antiasthmatic agent. Synonyms: 4-O-Des(difluoromethyl) Roflumilast; 3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-hydroxybenzamide. Grades: > 95%. CAS No. 475271-62-6. Molecular formula: C16H14Cl2N2O3. Mole weight: 353.20.
Roflumilast Impurity D
An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: Benzoic acid, 3-(cyclopropylmethoxy)-4-hydroxy-. CAS No. 1243391-44-7. Molecular formula: C11H12O4. Mole weight: 208.21.
Roflumilast Impurity E
An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: 3-O-Decyclopropyl Roflumilast; Roflumilast metabolite M05; 3-(Hydroxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide. CAS No. 1391052-76-8. Molecular formula: C13H8Cl2F2N2O3. Mole weight: 349.11.
Roflumilast Impurity H
An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: 3,4-Bis(difluoromethoxy) Roflumilast; Bis-difluoromethoxy Roflumilast impurity. CAS No. 162401-30-1. Molecular formula: C14H8Cl2F4N2O3. Mole weight: 399.12.
Roflumilast N-Oxide
An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: N-(3,5-Dichloro-1-oxopyridin-4-yl)-4-difluoromethoxy-3-cyclopropyl- methoxybenzamide; 3,5-Dichloro-4-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzamido)pyridine 1-oxide. Grades: > 95%. CAS No. 292135-78-5. Molecular formula: C17H14Cl2F2N2O4. Mole weight: 419.21.
Roflumilast N-Oxide
Roflumilast-N-oxide is the active metabolite of Roflumilast. Group: Biochemicals. Alternative Names: 3- (Cyclopropylmethoxy) -N- (3, 5-dichloro-1-oxido-4-pyridinyl) -4- (difluoromethoxy) benzamide; N-(3,5-Dichloro-1-oxopyridin-4-yl)-4-difluoromethoxy-3-cyclopropyl-methoxybenzamide. Grades: Highly Purified. CAS No. 292135-78-5. Pack Sizes: 2.5mg. US Biological Life Sciences.
Roflurane. Uses: Designed for use in research and industrial production. Additional or Alternative Names: bromo-2-trifluoro-1,1,2-ethyl-methyl ether; DA-893; Methyl-<1,1,2-trifluor-2-brom-aethyl>-aether; Ethane,2-bromo-1,1,2-trifluoro-1-methoxy; 1,1,2-Trifluor-2-bromethylmethylether; Rofluranum; Roflurano; Rofluran; 1,1,2-trifluoro-2-bromoethyl ether; R. Product Category: Heterocyclic Organic Compound. CAS No. 679-90-3. Molecular formula: C3H4BrF3O. Mole weight: 192.962. Purity: 0.96. IUPACName: 2-bromo-1,1,2-trifluoro-1-methoxyethane. Canonical SMILES: COC(C(F)Br)(F)F. Density: 1.687g/cm³. Product ID: ACM679903. Alfa Chemistry ISO 9001:2015 Certified.
Rogaratinib
Rogaratinib is a pan inhibitor of human fibroblast growth factor receptors (FGFRs). It reduced proliferation in FGFR-addicted cancer cell lines of various cancer types including lung, breast, colon and bladder cancer. Synonyms: BAY-1163877; BAY 1163877; BAY1163877. CAS No. 1443530-05-9. Molecular formula: C23H26N6O3S. Mole weight: 466.6.
Rogaratinib
Rogaratinib (BAY1163877) is a potent and selective fibroblast growth factor receptor ( FGFR ) inhibitor. Rogaratinib inhibits FGFRs with IC50s of 11.2 nM (FGFR1), <1 nM (FGFR2), 18.5 nM (FGFR3), 127 nM (VEGFR3/FLT4), 201 nM (FGFR4), respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY1163877. CAS No. 1443530-05-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100019.
Roginolisib
Roginolisib (MSC2360844; IOA-244) is a potent, orally active and selective PI3Kδ inhibitor, with an IC 50 of 145 nM. Roginolisib shows highly selective against a panel of 278 additional kinases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MSC2360844; IOA-244. CAS No. 1305267-37-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135827.
Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Synonyms: (5S, 8S) -8- ( ( (R) -1- (3, 5-bis (trifluoromethyl) phenyl) ethoxy) methyl) -8-phenyl-1, 7-diazaspiro[45]decan-2-one; SCH619734; SCH-619734; SCH 619734; Varubi. Grades: >95%. CAS No. 552292-08-7. Molecular formula: C25H26F6N2O2. Mole weight: 500.49.
Rolapitant
Rolapitant (SCH619734) is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a K i of 0.66 nM. Rolapitant does not interact with CYP3A4. Rolapitant shows potent anti-emetic activity in a ferret emesis model [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH619734. CAS No. 552292-08-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14751.
Rolapitant (1R,2R,3R)-Isomer
An impurity of Rolapitant.Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Synonyms: SCHEMBL15453123; EX-A1288F; Rolapitant (1R,2R,3R)-Isomer; FIVSJYGQAIEMOC-XARZLDAJSA-N; (5R, 8R) -8-[[ (1R) -1-[3, 5-bis (trifluoromethyl) phenyl]ethoxy]methyl]-8-phenyl-1, 9-diazaspiro[4. 5]decan-2-one; 1214741-26-0. Grades: > 95%. CAS No. 1214741-26-0. Molecular formula: C25H26F6N2O2. Mole weight: 500.49.
Rolapitant (1R,2R,3S)-Isomer
An impurity of Rolapitant.Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Synonyms: SCHEMBL15453121; EX-A1288E; Rolapitant (1R,2R,3S)-Isomer; FIVSJYGQAIEMOC-AVIJNYRZSA-N; (5S, 8R) -8-[[ (1R) -1-[3, 5-bis (trifluoromethyl) phenyl]ethoxy]methyl]-8-phenyl-1, 9-diazaspiro[4. 5]decan-2-one; 1214741-25-9. Grades: > 95%. CAS No. 1214741-25-9. Molecular formula: C25H26F6N2O2. Mole weight: 500.49.
Rolapitant (1R,2S,3R)-Isomer
An impurity of Rolapitant.Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Synonyms: SCHEMBL12679453; EX-A1288G; Rolapitant (1R,2S,3R)-Isomer; FIVSJYGQAIEMOC-UZFJHSOTSA-N; (5R, 8S) -8-[[ (1R) -1-[3, 5-bis (trifluoromethyl) phenyl]ethoxy]methyl]-8-phenyl-1, 9-diazaspiro[4. 5]decan-2-one; 552292-73-6. Grades: > 95%. CAS No. 552292-73-6. Molecular formula: C25H26F6N2O2. Mole weight: 500.49.
Rolapitant (1S,2R,3R)-Isomer
An impurity of Rolapitant.Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Grades: > 95%. CAS No. 1214741-30-6. Molecular formula: C25H26F6N2O2. Mole weight: 500.49.
Rolapitant (1S,2R,3S)-Isomer
An impurity of Rolapitant.Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Synonyms: SCHEMBL15453127; EX-A1288D; Rolapitant (1S,2R,3S)-Isomer; FIVSJYGQAIEMOC-FNVCAUGXSA-N; (5S, 8R) -8-[[ (1S) -1-[3, 5-bis (trifluoromethyl) phenyl]ethoxy]methyl]-8-phenyl-1, 9-diazaspiro[4. 5]decan-2-one; 1214741-28-2. Grades: > 95%. CAS No. 1214741-28-2. Molecular formula: C25H26F6N2O2. Mole weight: 500.49.
Rolapitant (1S,2S,3R)-Isomer
An impurity of Rolapitant.Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Synonyms: Rolapitant (1S,2S,3R)-Isomer. Grades: > 95%. CAS No. 1214741-29-3. Molecular formula: C25H26F6N2O2. Mole weight: 500.49.
Rolapitant (1S,2S,3S)-Isomer
An impurity of Rolapitant.Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Synonyms: SCHEMBL15453126; EX-A1288H; Rolapitant (1S,2S,3S)-Isomer; FIVSJYGQAIEMOC-PBNUPURSSA-N; HMS3750I21; (5S, 8S) -8-[[ (1S) -1-[3, 5-bis (trifluoromethyl) phenyl]ethoxy]methyl]-8-phenyl-1, 9-diazaspiro[4. 5]decan-2-one; 1214741-27-1. Grades: > 95%. CAS No. 1214741-27-1. Molecular formula: C25H26F6N2O2. Mole weight: 500.49.
Rolapitant HCl hydrate
Rolapitant, also known as SCH-619734, is a potent, highly selective, long-acting Neurokinin-1 (NK-1) receptor antagonist with potential antiemetic activity. Unlike other available NK-1 receptor antagonists, rolapitant is not an inhibitor of Cytochrome P450 enzyme CYP3A4 and has a long elimination half-life, allowing a single dose to prevent both acute and late-phase CINV during the first 120 hours post-chemotherapy. Synonyms: (5S, 8S) -8- ( ( (R) -1- (3, 5-bis (trifluoromethyl) phenyl) ethoxy) methyl) -8-phenyl-1, 7-diazaspiro[4. 5]decan-2-one hydrochloride.; SCH619734 SCH-619734; SCH 619734; Rolapitant HCl; Rolapitant hydrochloride, Rolapitant, brand name: Varubi. CAS No. 914462-92-3. Molecular formula: C25H26F6N2O2.ClH.H2O. Mole weight: 554.95.
Rolapitant hydrochloride hydrate
Rolapitant hydrochloride hydrate (SCH619734 hydrochloride hydrate) is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a K i of 0.66 nM. Rolapitant hydrochloride hydrate does not interact with CYP3A4. Rolapitant hydrochloride hydrate shows potent anti-emetic activity in a ferret emesis model [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH619734 hydrochloride hydrate. CAS No. 914462-92-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16436.
Roletamide
Roletamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Roletamide;3-(2,5-Dihydro-1H-pyrrol-1-yl)-1-(3,4,5-trimethoxyphenyl)-2-propen-1-one;CL 59112. Product Category: Heterocyclic Organic Compound. CAS No. 10078-46-3. Molecular formula: C16H19NO4. Purity: 0.96. IUPACName: (E)-3-(2,5-dihydropyrrol-1-yl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one. Canonical SMILES: COC1=CC(=CC(=C1OC)OC)C(=O)C=CN2CC=CC2. Density: 1.203g/cm³. Product ID: ACM10078463. Alfa Chemistry ISO 9001:2015 Certified.
Rolinsatamab
Rolinsatamab is a humanized bispecific monoclonal antibody targeting both IL-4 and IL-13. CAS No. 2095467-30-2.
Rolipram
Rolipram is a selective PDE4 inhibitor that modulates cyclic AMP (cAMP) degradation. Study showed that rolipram induced neuronal differentiation of human bone marrow-mesenchymal stem cells (hBM-MSCs). It can be used as an anti-inflammatory agent. Uses: Antidepressive agents. Synonyms: ZK-62711; SB 95952; 4-(3-cyclopentyloxy-4-methoxyphenyl)pyrrolidin-2-one. Grades: >98%. CAS No. 61413-54-5. Molecular formula: C16H21NO3. Mole weight: 275.34.
Rolipram. Group: Biochemicals. Grades: Purified. CAS No. 61413-54-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Rolipram
Rolipram is a selective phosphodiesterases PDE4 inhibitor with IC 50 s of 3 nM, 130 nM and 240 nM for PDE4A, PDE4B, and PDE4D, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R,S)-Rolipram; (±)-Rolipram; ZK 62711. CAS No. 61413-54-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16900.
A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC50=800nM). A rolipram-insensitive PDE IV subtype is also known to exist. Also inhibits NF-kB and NFAT activation in Jurkat and primary T cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 61413-54-5. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Rolipram - CAS 61413-54-5
A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC?? = 800 nM). Group: Fluorescence/luminescence spectroscopy.