A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
S 07662. Group: Biochemicals. Grades: Purified. CAS No. 883226-64-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
S 07662
S 07662 is an inverse agonist of the constitutive androstane receptor (CAR). S 07662 inhibits CAR activity via recruitment of nuclear receptor co-repressor (NCoR). Synonyms: S07662; S 07662; S-07662; N-[(2-Methyl-3-benzofuranyl)methyl]-N'-(2-thienylmethyl)urea; 1-[(2-methyl-1-benzofuran-3-yl)methyl]-3-(thiophen-2-ylmethyl)urea. Grades: ≥98% by HPLC. CAS No. 883226-64-0. Molecular formula: C16H16N2O2S. Mole weight: 300.38.
S0859
S0859, an N-cyanosulphonamide compound, reversibly inhibit NBC-mediated pH(I) recovery (K i=1.7 mM). Synonyms: S0859; S-0859; S 0859. Grades: >98%. CAS No. 1019331-10-2. Molecular formula: C29H24ClN3O3S. Mole weight: 530.04.
S100 Calcium Binding Protein B, Positive Control (S100B)
S100 Calcium Binding Protein B, Positive Control (S100B). Group: Molecular Biology. Pack Sizes: 15ul. US Biological Life Sciences.
Worldwide
S107
S107 is a type 1 ryanodine receptor (RyR1) stabilizer that binds RyR1 and enhances the binding affinity of calstabin-1. S107 increased FKBP12 binding to RyR1 in SR vesicles in the presence of reduced glutathione and the NO-donor NOC12, with no effect in the presence of oxidized glutathione. Synonyms: 2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine hydrochloride; S107; S-107; S 107. CAS No. 927871-76-9. Molecular formula: C11H15NOS. Mole weight: 209.31.
An optically active metabolite of carbamazepine. Group: Biochemicals. Alternative Names: S-(+)-10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide, S-MHD. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
S-110483
S-110483 is a prostanoid EP4 receptor antagonist with immunomodulatory and analgesic activities. Human EP4 receptor binding assays showed a Ki value of 0.73 nmol/L for S-110483. Uses: The potential prevention of rheumatoid arthritis (ra). Synonyms: S-110483; S 110483; S110483.
S12 is a mutant RAS peptide containing the Gly (G) to Ser (S12) substitution. The sequence of the peptide is KLVVVGASGVGKS [1]. Uses: Scientific research. Group: Peptides. CAS No. 257872-93-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2361.
S 12
S 12 is a survivin inhibitor that alters spindle formation, resulting in mitotic arrest (by disrupting metaphase at the G2/M stage) and apoptosis. It inhibits cell proliferation and tumor growth independently of p53 status. Uses: Antitumor agent. Synonyms: S12; NSC201630; MLS000029787; SMR000010018; S 12; NSC 201630; MLS 000029787; SMR 000010018; S-12; NSC-201630; MLS-000029787; SMR-000010018; 3-[2-(1,3-benzodioxol-5-yl)-2-oxoethyl]-5-bromo-3-hydroxy-1,3-dihydro-2H-indol-2-one. Grades: 99%. CAS No. 258264-62-9. Molecular formula: C17H12BrNO5. Mole weight: 390.18.
S-((1-(2,2-Dimethyl-5-oxo-1,3-dioxolan-4-yl)cyclopropyl)methyl) Ethanethioate is an intermediate in the synthesis of Montelukast (M568000), a selective leukotriene D4-receptor antagonist used as an antiasthmatic agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
S-((1-(2,2-Dimethyl-5-oxo-1,3-dioxolan-4-yl)cyclopropyl)methyl) Ethanethioate is an intermediate of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: Ethanethioic acid, S-[[1-(2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl)cyclopropyl]methyl] ester. Molecular formula: C11H16O4S. Mole weight: 244.31.
It shows anti-inflammatory and anti-anaphylactic effects in vivo and inhibits histamine release from rat mast cells in vitro. Synonyms: S-(alpha,beta-Dicarboxyethyl)glutathione; H-Glu(Cys(1,2-dicarboxyethyl)-Gly-OH)-OH. Grades: 95%. CAS No. 1115-52-2. Molecular formula: C14H21N3O10S. Mole weight: 423.40.
Heterocyclic Organic Compound. Alternative Names: S-1,2-Epoxypentane;(S)-2-Propyloxirane. CAS No. 123731-68-0. Molecular formula: C5H10O. Mole weight: 86.13. Catalog: ACM123731680.
S)-(-)-1,2-Propylene carbonate
1g Pack Size. Group: Building Blocks, Chiral Compounds, Organics. Formula: C4H6O3. CAS No. 51260-39-0. Prepack ID 22687224-1g. Molecular Weight 102.09. See USA prepack pricing.
S130
S130 is a high affinity, selective inhibitor of ATG4B (a major cysteine protease) with an IC 50 of 3.24 μM. S130 suppresses autophagy flux [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1160852-22-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112818.
s 135
Heterocyclic Organic Compound. CAS No. 104679-67-6. Catalog: ACM104679676.
S14161
Potent antileukemia and antimyeloma compound. Apoptosis inducer, delays tumor growth. Cyclin D2 promoter transactivation inhibitor. PI3 kinase (PI3K) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 883046-50-2. Pack Sizes: 1mg, 5mg. Molecular Formula: C17H14FNO4. US Biological Life Sciences.
Worldwide
S14161
S14161 is an inhibitor of cyclins D1-D3 expression that inhibits phosphoinositide 3-kinase activity. It induces apoptosis in myeloma and leukemia cell lines with IC50 value of 10 μM. Synonyms: 8-Ethoxy-2-(4-fluorophenyl)-3-nitro-2H-chromene. Grades: ≥99%. CAS No. 883046-50-2. Molecular formula: C17H14FNO4. Mole weight: 315.3.
S 14506
S 14506 is a potent and selective 5-HT1A agonist. Synonyms: S-14506; S 14506; S14506; 4-fluoro-N-[2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl]benzamide. Grades: 98%. CAS No. 135722-25-7. Molecular formula: C24H26FN3O2. Mole weight: 407.48.
S14506 HCl
S 14506 is a highly potent selective 5-HT1A receptor full agonist (pKi values are 9.0, 6.6, 7.5, 6.6 and < 6.0 for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT2 and 5-HT3 receptors respectively). It potentially binds between the agonist binding site and the G protein interaction switch site, affecting the activation mechanism, and may display positive cooperativity. Group: Agonists. Alternative Names: S 14506 HCl; S14506HCl; S14506 HCl; S-14506. CAS No. 286369-38-8. Molecular formula: C24H27ClFN3O2. Mole weight: 443.95. Appearance: Solid powder. Purity:>98%. IUPACName: 4-Fluoro-N-[2-[4-(7-methoxy-1-naphthalenyl)-1-piperazinyl]ethyl]benzamide hydrochloride. Canonical SMILES: O=C (NCCN1CCN (C2=C3C=C (OC)C=CC3=CC=C2)CC1)C4=CC=C (F)C=C4. [H]Cl. Catalog: ACM286369388.
S 14506 hydrochloride
S 14506 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 286369-38-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
S 14506 hydrochloride
S 14506 hydrochloride is a highly potent and selective 5-HT1A receptor full agonist (pKi = 9.0, 6.6, 7.5, 6.6 and < 6.0 for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT2 and 5-HT3 receptors, respectively). S 14506 possibly binds between the agonist binding site and the G protein interaction switch site. S 14506 exhibits anxiolytic and antihypertensive properties. Synonyms: S 14506 hydrochloride; S14506 hydrochloride; S-14506 hydrochloride; 4-Fluoro-N-[2-[4-(7-methoxy-1-naphthalenyl)-1-piperazinyl]ethyl]benzamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 286369-38-8. Molecular formula: C24H26FN3O2.HCl. Mole weight: 443.94.
S-14506 hydrochloride
S-14506 hydrochloride is a potent 5-HT1A agonist, as well as 5-HT 2A/2C antagonist. S-14506 hydrochloride displays dopamine antagonist properties by blocking dopamine D2 receptors. S-14506 hydrochloride inhibits the in vivo binding of [3H]raclopride in striatum and olfactory bulbs. S-14506 hydrochloride has the potential for the research of anxiolytic agent [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 286369-38-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110024.
S14-95
S14-95 is an inhibitor of the JAK/STAT pathway isolated from Penicillium sp. 14-95. It inhibits the IFN-gamma mediated expression of the reporter gene with IC50 values of 2.5 to approximately 5 mg/ml. It inhibits the expression of the proinflammatory enzymes COX-2 and NOS II at 5 microg/ml (10.8 mM) in LPS/IFN-gamma stimulated J774 mouse macrophages. Molecular formula: C28H34O5. Mole weight: 450.57.
S-15183a
S-15183a is a sphingosine kinase inhibitor produced by Zopfiella inermis SANK 15183. It inhibited sphingosine kinase from rat liver with IC50 value of 2.5 μmol/L. It also inhibited endogenous SPH kinase activity in intact platelets. Synonyms: S-15183 a. Molecular formula: C25H36O5. Mole weight: 416.5.
S-15183b
S-15183b is a sphingosine kinase inhibitor produced by Zopfiella inermis SANK 15183. It inhibited sphingosine kinase from rat liver with IC50 value of 2.5 μmol/L. Synonyms: S-15183 b. Molecular formula: C27H40O5. Mole weight: 444.6.
S-15535
S-15535 is a highly selective 5-HT 1A receptor ligand. S-15535 is an antagonist of postsynaptic 5-HT 1A receptors and an agonist of presynaptic 5-HT 1A receptors. S-15535 can be used in research on psychiatric disorders, such as anti-anxiety [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 146998-34-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116076.
S16961
S16961 is a nicotinic receptor agonist with antihyperlipidaemic property which was developed for the treatment of Hyperlipidaemia in France (PO). Synonyms: 2,3-di(hexadecanoyloxy)propyl pyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 2,3-bis((1-oxohexadecyl)oxy)propyl ester; S-16961; AC1L434K; S-16961-1; S 169611. CAS No. 153874-14-7. Molecular formula: C41H71NO6. Mole weight: 674.01.
S 17092
S 17092 (S 17092-1) is an orally active cerebral prolyl-endopeptidase (PEP) inhibitor with an IC 50 of 1.2 nM. S 17092 inhibits cell apoptosis. S 17092 mechanism of action is to inhibit the activity of PEP, slowing down the degradation of neuroactive peptides and thus enhancing memory function. S 17092 can be used for the research of memory impairment and cognitive disorders associated with cerebral aging [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S 17092-1. CAS No. 176797-26-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15114.
S-17092
S-17092, a thiazolidine derivative, has been found to be a prolyl endopeptidase inhibitor which could be effective in the treatment of cognition disorder and be probably be significant in studies of Alzheimer's and Parkinson's disease. It is still under Phase-I trial. Synonyms: S-17092; S 17092; S17092. [(2S,3aS,7aS)-2-(1,3-thiazolidine-3-carbonyl)-2,3,3a,4,5,6,7,7a-octahydroindol-1-yl]-[(1R,2R)-2-phenylcyclopropyl]methanone. Grades: 98%. CAS No. 176797-26-5. Molecular formula: C22H28N2O2S. Mole weight: 384.54.
S186
S186 is a new type of strontium-specific chelator. Uses: Scientific research. Group: Signaling pathways. CAS No. 97759-16-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13950.
S186
S186 is a kind of sodium salts of calcium-acetylpropylamine phosphonate(APA). It is a new strontium-specific chelating agent. It has also been approved by Shanghai Municipal Health Bureau for emergency medical use in China. Synonyms: S186; S 186; S-186. Grades: >98%. CAS No. 97759-16-5. Molecular formula: C5H13CaNNaO7P2+3. Mole weight: 324.17.
S 18986
S 18986 is a positive allosteric modulator of AMPA receptors that enhances (S)-AMPA-mediated noradrenaline release in rat hippocampal and frontal cortex slices. S 18986 exhibits neuroprotective and cognitive-enhancing properties in rodent behavioral models. Synonyms: S18986; S-18986; S 18986; S18986-1; S-18986-1; S 18986-1. (3aS)-2,3,3a,4-Tetrahydro-1H-pyrrolo[2,1-c][1,2,4]benzothiadiazine-5,5-dioxide. Grades: ≥98% by HPLC. CAS No. 175340-20-2. Molecular formula: C10H12N2O2S. Mole weight: 224.28.
S 18986
S 18986. Group: Biochemicals. Grades: Purified. CAS No. 175340-20-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
S 18986
S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors. S 18986 shows cognitive enhancing properties in rodents. S 18986 activates the release of noradrenaline and acetylcholine in rat hippocampus and enhances rat memory in object-recognition tests [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 175340-20-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10936.
A positive allosteric modulator selective for the AMPA receptors. A nootropic and neuroprotective agents frequently used in researches studying cognition, memory, and aging related cognitive declines. Induces production of BNDF and AMPA-mediated release of noradrenaline and acetylcholine. Biologically viable admitted systematically. Group: Biochemicals. Grades: Highly Purified. CAS No. 175340-20-2. Pack Sizes: 5mg. Molecular Formula: C??H??N?O?S. US Biological Life Sciences.
Worldwide
S-19159
S-19159 is a modulator of neurite outgrowth produced by the ascomycete Preussia aemulans. Synonyms: S 19159; S19159. Molecular formula: C30H44O5. Mole weight: 484.7.
S- ( + ) -1-Aminotetra hydronaphthalene
S- ( + ) -1-Aminotetra hydronaphthalene . Group: Biochemicals. Alternative Names: (S)-(+)-1,2,3,4-Tetrahydro-1-naphthylamine; (S)-(+)-1-Aminotetralin; (S)-1,2,3,4-Tetrahydro-1-naphthalenamine. Grades: Highly Purified. CAS No. 23357-52-0. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C10H13N. US Biological Life Sciences.
S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) and refers to the Alkyl-Chain composition. S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is the linker portions of the molecules employed for mAb attachment purposes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2127875-65-2. Pack Sizes: 50 mg; 100 mg; 250 mg. Product ID: HY-129942.
S-1 methanandamide
S-1 methanandamide is a CB1 receptor ligand. It inhibits electrically evoked contractions in isolated mouse vasa deferentia with an IC50 value of 230 nM. Synonyms: (R)-methanandamide; (S)-(-)-Arachidonyl-1'-Hydroxy-2'-Propylamide; (5Z,8Z,11Z,14Z)-N-[(2S)-1-hydroxypropan-2-yl]icosa-5,8,11,14-tetraenamide. Grades: ≥98%. CAS No. 157182-50-8. Molecular formula: C23H39NO2. Mole weight: 361.6.
S- (1-Methyl-2-hydroxyethyl) glutathione (Mixture of Diastereomers)
A glutamyl cysteinyl glycine (GSH) derivative. Group: Biochemicals. Alternative Names: L-γ-Glutamyl-S-(1-methyl-2-hydroxyethyl)-L-cysteinylgycine; N-[N-L-γ-glutamyl-S-(1-methyl-2-hydroxyethyl)-L-cysteinyl]glycine. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
S1P1 agonist 1
S1P1 Agonist 1 is a S1P1 agonist with immunomodulatory activities. Uses: Scientific research. Group: Signaling pathways. CAS No. 1220973-37-4. Pack Sizes: 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-104069.
S1P1 Agonist III
S1P1 Agonist III, a S1P1 agonist, has been found to induce the lymphocyte counts' reduction in circulating blood and have potentials in study of autoimmune diseases. IC50: 18 nM(EC50). Uses: S1p1 agonist iii is a s1p1 agonist that has been found to induce the lymphocyte counts' reduction in circulating blood and have potentials in study of autoimmune diseases. Synonyms: S1P1 Agonist III; CHEMBL1938952; 4088AH; BDBM50361891; IN2195; TC-G 1006; TC G 1006; TCG1006; TC G-1006; TC-G-1006. Grades: 98%. CAS No. 1324003-64-6. Molecular formula: C21H16F3N3O3. Mole weight: 415.37.
S1P4 Receptor Antagonist (CYM50358)
An arylcarboxamide that acts as a potent and selective sphingosine-1-phosphate receptor 4 (S1P4) antagonist (IC50=25nM), among a panel of five S1P receptors. It is shown to inhibit other S1P isoforms only at much higher concentrations (IC50 = 6.4uM, 3.9uM, 5.5uM, and 25uM for S1P1, S1P2, S1P5, and S1P3 (95% inhibition), respectively). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
S- (1-Pentyl-5-biotinylamido) glutathione. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
S1PR1 modulator 1
S1PR1 modulator 1 is a selective S1PR1 inhibitor, with a pIC 50 of 7.6, with >40- and >80-fold selectivity, over the other S1PR isoforms S1PR2/3/4 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2328109-05-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-126145.
S1PR-MO-1
The modulator of sphingosine-1-phosphate receptor. Synonyms: Cyclobutanecarboxylic acid, 3-[[1-[4-[5-[4-(2-methylpropyl)phenyl]-1,2,4-oxadiazol-3-yl]phenyl]ethyl]amino]-. CAS No. 1149727-61-6. Molecular formula: C25H29N3O3. Mole weight: 419.52.
S1RA
The sigma-1 (σ1) receptor is an intracellular, non-opioid receptor that is abundantly expressed in the central nervous system as well as peripherally. S1RA is a potent, selective antagonist of σ1 receptors (Ki = 17 nM) that weakly binds σ2 receptors (Ki = 9,300 nM). Synonyms: S1RA; 878141-96-9; E-52862; ZW18DSD1H4; 4-(2-((5-methyl-1-(naphthalen-2-yl)-1H-pyrazol-3-yl)oxy)ethyl)morpholine;4-[2-[[5-methyl-1-(2-naphthalenyl)-1h-pyrazol-3-yl]oxy]ethyl] morpholine; 4-[2-[[5-methyl-1-(2-naphthalenyl)-1H-pyrazol-3-yl]oxy]ethyl]-morpholine; MORPHOLINE, 4-(2-((5-METHYL-1-(2-NAPHTHALENYL)-1H-PYRAZOL-3-YL)OXY)ETHYL)-. CAS No. 878141-96-9. Molecular formula: C20H23N3O2. Mole weight: 337.42.
S1RA
S1RA (E-52862) is a highly selective σ1 receptor (σ1R) antagonist with K i s of 17 nM and 23.5 nM for human σ1R and guinea pig σ1R, respectively. S1RA has Moderate antagonistic activity for human 5-HT 2B receptor (K i = 328 nM). S1RA has antinociceptive effects in neuropathic pain models. S1RA prevents mechanical and cold hypersensitivity in Oxaliplatin (HY-17371)-treated mice [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E-52862. CAS No. 878141-96-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-18099.
S1RA hydrochloride
S1RA (E-52862) hydrochloride is an orally active and selective sigma-1 receptor ( σ1R ) antagonist with a K i value of 17 nM. S1RA hydrochloride shows good selectivity against σ2R (K i >1000 nM). S1RA hydrochloride is a human 5-HT2B receptor antagonist with an IC 50 value of 4.7 μM. S1RA hydrochloride inhibits neuropathic pain and activity-induced spinal sensitization [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E-52862 hydrochloride. CAS No. 1265917-14-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-18099A.
S1RA Hydrochloride
The hydrochloride salt form of S1RA which is a σ1 receptor antagonist that has been found to have potential effect in pain therapy. It is still under Phase II clinical trial. IC50: 17 nM (Ki). Uses: The hydrochloride salt form of s1ra which is a σ1 receptor antagonist that has been found to have potential effect in pain therapy. Synonyms: S1RA hydrochloride; S1RA (hydrochloride); E-52862 hydrochloride; E 52862 hydrochloride; E52862 hydrochloride; SCHEMBL99116; UNII-18XZ7850YN. Grades: 98%. CAS No. 1265917-14-3. Molecular formula: C20H24ClN3O2. Mole weight: 373.88.
S-(-)-1-(t-Butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanol maleate salt
S-(-)-1-(t-Butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanol maleate salt. Group: Biochemicals. Alternative Names: Timolol maleate. Grades: Highly Purified. CAS No. 26921-17-5. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C13H24N4O3S·C4H4O4. US Biological Life Sciences.
S)-1-(tert-Butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol. Group: Biochemicals. Alternative Names: Timolol. Grades: Highly Purified. CAS No. 26839-75-8,26921-17-5. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C13H24N4O3S. US Biological Life Sciences.
Worldwide
S2101
S2101 is a lysine-specific demethylase 1 ( LSD1 ) inhibitor with an IC 50 of 0.99 μM, K i of 0.61 μM and K inact /K i of 4560 M/s [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1239262-36-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110277.
S 2101
S 2101 is a LSD1 inhibitor (IC50 = 990 nM; Ki = 610 nM), displaying selectivity for LSD1 over MAO-B and MAO-A (Ki = 17 and 110 μM, respectively). Synonyms: (1R, 2S) -rel-2-[3, 5-Difluoro-2- (phenylmethoxy) phenyl]cycloprpanamine hydrochloride; HY-110277; S-2101; HY 110277; S 2101; HY110277; S2101. Grades: ≥98% by HPLC. CAS No. 1239262-36-2. Molecular formula: C16H15F2NO.HCl. Mole weight: 311.75.
S2116
S2116, a N-alkylated tranylcypromine (TCP) derivative, is a potent lysine-specific demethylase 1 (LSD1) inhibitor. S2116 increases H3K9 methylation and reciprocal H3K27 deacetylation at super-enhancer regions. S2116 induces apoptosis in TCP-resistant T-cell acute lymphoblastic leukemia (T-ALL) cells by repressing transcription of the NOTCH3 and TAL1 genes. S2116 significantly retardes the growth of T-ALL cells in xenotransplanted mice [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2262489-89-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136522.