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| Product | Description | |
|---|---|---|
| (+)-MK 801 | (+)-MK 801 is a potent NMDA receptor antagonist. Synonyms: Neurogard; 10,11-dihydro-5-methyl-5h-dibenzo[a,d]cyclohepten-5,10-imine. CAS No. 70449-94-4. Molecular formula: C16H15N. Mole weight: 221.297. |  |
| (+)-MK 801 Hydrogen Maleate | (+)-MK 801 Hydrogen Maleate. Group: Biochemicals. Alternative Names: (5S)-10, 11-Dihydro-5-methyl-5H-dibenzo[a, d]cyclohepten-5, 10-imine, (2Z)-2-butenedioate (1:1); (5S)-10, 11-Dihydro-5-methyl-5H-dibenzo[a, d]cyclohepten-5, 10-imine (Z)-2-Butenedioate (1:1); Dizocilpine Hydrogen Maleate; Dizocilpine Maleate. Grades: Highly Purified. CAS No. 77086-22-7. Pack Sizes: 25mg. Molecular Formula: C20H19NO4, Molecular Weight: 337.37. US Biological Life Sciences. |  Worldwide |
| (-)-MK 801 maleate | (-)-MK 801 maleate. Group: Biochemicals. Grades: Purified. CAS No. 121917-57-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| (+)-MK 801 maleate | (+)-MK 801 maleate. Group: Biochemicals. Grades: Purified. CAS No. 77086-22-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| (+)-MK-801 maleate | (-)-MK-801 maleate is a potent, selective and non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM that acts at the NMDA receptor-operated ion channel as an open channel blocker. It blocks NMDA receptors in a use- and voltage-dependent manner, since the channel must open for the drug to bind inside it. It anti-convulsant and likely has dissociative anesthetic properties, but it is not used clinically for this purpose due to the discovery of brain lesions, called Olney's lesions in test rats. It were used to treat hyperalgesia in the diabetic neuropathic pain (DNP). It is used in various ischemia treatments. It has been shown to be protective in various models of ischemia as well as to inhibit behavioral sensitization to certain psychostimulants. Uses: (-)-mk-801 maleate blocks nmda receptors in a use- and voltage-dependent manner, since the channel must open for the drug to bind inside it. it were used to treat hyperalgesia in the diabetic neuropathic pain (dnp). it is used in various ischemia treatments. it has been shown to be protective in various models of ischemia as well as to inhibit behavioral sensitization to certain psychostimulants. Synonyms: (-)-MK-801 maleate; (-)-MK 801 maleate; (-)-MK801 maleate; (+)-10,11-Dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-diyldiammonium maleate;Dizocilpine maleate;(5R,10S)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine hydrogen maleate;Dizocilpine maleate;Dizocilpine hydrogen maleate;(+)-MK-801 hydrogen maleate. Grades: >99 %. CAS No. 77086-22-7. Molecular formula: C20H19NO4. Mole weight: 337.37. | |
| (-)-MK 801 Maleate | MK-801 is a potent, selective and non-competitive NMDA receptor antagonist with Kd of 37.2 nM in rat brain membranes. Synonyms: (-)-MK 801 hydrogen maleate; (-)-MK 801 Maleate; (-)-MK 801 (Maleate). Grades: >98%. CAS No. 121917-57-5. Molecular formula: C16H15N.C4H4O4. Mole weight: 337.37. | |
| (+)-MK 801 Maleate - CAS 77086-22-7 | A highly potent, selective, and non-competitive NMDA receptor antagonist that acts by binding to a site located within the NMDA-associated ion channel, thus preventing Ca2+ flux. Group: Fluorescence/luminescence spectroscopy. |  |
| Dizocilpine maleate | Dizocilpine maleate (MK-801 maleate) is a potent, selective and non-competitive NMDA receptor antagonist with K d of 37.2 nM in rat brain membranes. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-MK 801 Maleate. CAS No. 77086-22-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15084. |  |
| Diphenidine hydrochloride | Diphenidine is a homeomorph of the NMDA receptor channel blocker, MK 801, that has been identified as a designer drug. It has been studied as a neuroprotective agent for the treatment of brain injury following hypoxia. Synonyms: DEP; 1-(1,2-diphenylethyl)piperidine;dl-1,2-Diphenyl-1-piperidinoethane hydrochloride; (+-)-1-(1,2-Diphenylethyl)piperidine hydrochloride; Piperidine, 1-(1,2-diphenylethyl)-, hydrochloride, (+-)-; Diphenidine Hydrochloride. Grades: ≥98%. CAS No. 28383-15-5. Molecular formula: C19H23N·HCl. Mole weight: 301.9. | |
| Dizocilpine | Dizocilpine is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM. Synonyms: MK-801; MK 801; MK801; (5S)-5-methyl-10,11-dihydro-5H-5,10-epiminodibenzo[a,d][7]annulene. Grades: ≥98%. CAS No. 77086-21-6. Molecular formula: C16H15N. Mole weight: 221.303. | |
| TC-E 5005 | TC-E 5005 is a potent and selective PDE10A inhibitor (IC50 = 7.28, 239, 779, 919, 3100 and 3700 nM at PDE10A, 2A, 11A, 5A, 7B and 3A respectively, and >5000 nM at PDE1B, 4A, 6, 8A and 9A). TC-E 5005 reverses MK 801-induced hyperactivity and stereotypy in vivo. It also inhibits adrenergic and neurogenic smooth muscle contractions in the human prostate. Synonyms: TC-E 5005; TC E-5005; TC E 5005; TC-E-5005; TCE5005; 2-Methoxy-6,7-dimethyl-9-propyl-imidazo[1,5-a]pyrido[3,2-e]pyrazine. Grades: ≥99% by HPLC. CAS No. 959705-64-7. Molecular formula: C15H18N4O. Mole weight: 270.33. | |
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