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| Product | Description | |
|---|---|---|
| (3R,11bR)-Tetrabenazine | (3R,11bR)-Tetrabenazine is one of Tetrabenazine impurities. Tetrabenazine is a VMAT-inhibitor used for treatment of hyperkinetic movement disorder. It is a monoamine-depleting and a dopamine-receptor-blocking drug and is an effective and safe drug for the treatment of a variety of hyperkinetic movement disorders. Synonyms: (3R,11bR)-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-one; (+)-TBZ; (+)-Tetrabenazine; (3R,11bR)-TBZ. Grades: > 98%. CAS No. 1026016-83-0. Molecular formula: C19H27NO3. Mole weight: 317.42. |  |
| (3R,11bR)-Tetrabenazine (1S)-(+)-10-Camphorsulfonate | (3R,11bR)-Tetrabenazine (1S)-(+)-10-Camphorsulfonate is an analogue of Tetrabenazine, which is a VMAT inhibitor used in the treatment of hyperkinetic movement disorder. Synonyms: (+)-TBZ (1S)-(+)-10-Camphorsulfonate; (+)-Tetrabenazine (1S)-(+)-10-Camphorsulfonate; (1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic Acid compd. with (3R,11bR)-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-one. Grades: 98%. CAS No. 1223399-57-2. Molecular formula: C29H43NO7S. Mole weight: 549.72. | |
| 9-Desmethyl-alpha-Dihydro-Tetrabenazine | 9-Desmethyl-alpha-Dihydro-Tetrabenazine is one of Tetrabenazine derivatives. Tetrabenazine is a VMAT-inhibitor used for treatment of hyperkinetic movement disorder. It is a monoamine-depleting and a dopamine-receptor-blocking drug and is an effective and safe drug for the treatment of a variety of hyperkinetic movement disorders. Synonyms: (+)-9-O-Desmethyl-a-dihydrotetrabenazine; 1H-Naphtho[2,3-c]pyran-3-aceticacid,3,4,5,10-tetrahydro-9-hydroxy-5,10-dioxo-1-propyl-,(1R,3S); Desoxyfrenolicin; (2R,3R,11bR)-9-O-desmethyldihydrotetrabenazine; (+)-deoxyfrenolicin; 1H-Naphtho(2,3-c)pyran-3-acetic acid,3,4,5,10-tetrahydro-9-hydroxy-5,10-dioxo-1-propyl-,(1R-trans); 9-o-Desmethyl-alpha-dihydrotetrabenazine; 3-isobutyl-10-methoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinoline-2,9-diol. Grades: ≥95%. CAS No. 1065193-59-0. Molecular formula: C18H27NO3. Mole weight: 305.41. | |
| Tetrabenazine | Tetrabenazine is a VMAT inhibitor used for the treatment of hyperkinetic movement disorder. It is a monoamine-depleting and dopamine-receptor-blocking drug, and is an effective and safe drug for the treatment of a variety of hyperkinetic movement disorders. Synonyms: 2H-Benzo[a]quinolizin-2-one, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-, (3R,11bR)-rel-; 2H-Benzo[a]quinolizin-2-one, 1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; 2H-Benzo[a]quinolizin-2-one, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-, cis-; (±)-Tetrabenazine; cis-2-Oxo-3-isobutyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bH-benzo[a]quinolizine; NSC 169886; NSC 172187; Ro 1-9569; Rubigen; Xenazine. Grades: >98%. CAS No. 58-46-8. Molecular formula: C19H27NO3. Mole weight: 317.42. | |
| (+)-Tetrabenazine | (+)-Tetrabenazine ((+)-TBZ; (3R,11bR)-TBZ; (3R,11bR)-Tetrabenazine) is a reversible inhibitor of vesicular monoamine transporter 2 (VMAT-2), inhibits transport by VMAT2 with 10-fold greater potency than transport by VMAT1. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-TBZ; (3R,11bR)-TBZ; (3R,11bR)-Tetrabenazine. CAS No. 1026016-83-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0590B. |  |
| (2R,3R,11bR)-Dihydrotetrabenazine D-Val | (2R,3R,11bR)-Dihydrotetrabenazine D-Val is an impurity of Tetrabenazine, which is a VMAT inhibitor used in the treatment of hyperkinetic movement disorder. Synonyms: (2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido(2,1-a)isoquinolin-2-yl D-valinate; D-Valine (2R,3R,11bR)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo(a)quinolizin-2-yl ester. CAS No. 1025504-59-9. Molecular formula: C24H38N2O4. Mole weight: 418.57. | |
| (2R,3S,11bR)-Dihydrotetrabenazine | (2R,3S,11bR)-Dihydrotetrabenazine is an enantiomer of (2S,3R,11bS)-Dihydrotetrabenazine (D454920). Tetrabenazine and dihydrotetrabenazines are potent inhibitors of vesicular monoamine transporter 2 (VMAT2). Furthermore, the derivatives of these compounds are potential drug candidates for treating various diseases such as Huntingtons disease and other hyperkinetic disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 862377-31-9. Pack Sizes: 10mg, 25mg. Molecular Formula: C19H29NO3, Molecular Weight: 319.44. US Biological Life Sciences. |  Worldwide |
| (2S,3R,11bR)-Dihydrotetrabenazine D-Val | (2S,3R,11bR)-Dihydrotetrabenazine D-Val is an impurity of Tetrabenazine, which is a VMAT inhibitor used in the treatment of hyperkinetic movement disorder. Synonyms: (2S,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido(2,1-a)isoquinolin-2-yl D-valinate; D-Valine (2S,3R,11bR)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo(a)quinolizin-2-yl ester. Molecular formula: C24H38N2O4. Mole weight: 418.57. | |
| (2S,3R,11bR)-Dihydrotetrabenazine L-Val | (2S,3R,11bR)-Dihydrotetrabenazine L-Val is an impurity of Tetrabenazine, which is a VMAT inhibitor used in the treatment of hyperkinetic movement disorder. Synonyms: (2S,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido(2,1-a)isoquinolin-2-yl L-valinate; L-Valine (2S,3R,11bR)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo(a)quinolizin-2-yl ester. Molecular formula: C24H38N2O4. Mole weight: 418.57. | |
| (2S,3R,11bS)-Dihydrotetrabenazine | (2S,3R,11bS)-Dihydrotetrabenazine is an enantiomer of (2R,3S,11bR)-Dihydrotetrabenazine (D454925). Tetrabenazine and dihydrotetrabenazines are potent inhibitors of vesicular monoamine transporter 2 (VMAT2). Furthermore, the derivatives of these compounds are potential drug candidates for treating various diseases such as Huntingtons disease and other hyperkinetic disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 8862377-33-1. Pack Sizes: 10mg, 25mg. Molecular Formula: C19H29NO3, Molecular Weight: 319.44. US Biological Life Sciences. | Worldwide |
| 9-Desmethyl-beta-Dihydro Tetrabenazine | 9-Desmethyl-beta-Dihydro Tetrabenazine is an impurity of Tetrabenazine, which is a VMAT inhibitor used in the treatment of hyperkinetic movement disorder. Synonyms: (2S,3R,11bR)-3-Isobutyl-10-methoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinoline-2,9-diol; 9-o-Desmethyl-beta-htbz; 9-o-Desmethyl-beta-dihydrotetrabenazine; 2H-Benzo(a)quinolizine-2,9-diol, 1,3,4,6,7,11b-hexahydro-10-methoxy-3-(2-methylpropyl)-, (2S,3R,11bR)-. CAS No. 1214267-68-1. Molecular formula: C18H27NO3. Mole weight: 305.41. | |
| (+)-α-Dihydrotetrabenazine | (+)-α-Dihydrotetrabenazine is an impurity of Tetrabenazine, which is a VMAT-2 inhibitor and has been found to be effective in the treatment of hyperkinetic movement disorder at some extent. Synonyms: [2R-(2α,3β,11bβ)]-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol; (+)-(2R,3R,11bR)-Dihydrotetrabenazine; (+)-DTBZ; (+)-Dihydrotetrabenazine; (2R,3R,11bR)-DHTBZ; Tetrabenazine Related Impurity 27(2R,3R,11bR); (+-)-3c-Isobutyl-9,10-dimethoxy-(11br)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isochinolin-2t-ol; trans-2 hydroxy-3 isobutyl-9,10 dimethoxy-1,2,3,4,6,7 hexahydro-11bH-benzo(a)quinolizine; 2H-Benzo[a]quinolizin-2-ol,1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-,(2R,3R,11bR); dihydrotetrabenazine, (2alpha, 3beta, 11bbeta)-isomer; TBZOH cpd. Grades: ≥ 95%. CAS No. 85081-18-1. Molecular formula: C19H29NO3. Mole weight: 319.44. | |
| alpha-Hydroxy Tetrabenazine | One metabolite impurity of Tetrabenazine, which is a VMAT-2 inhibitor and has been found to be effective in the treatment of hyperkinetic movement disorder at some extent. Synonyms: trans (2,3)-Dihydro Tetrabenazine; rel-(2R,3R,11bR)-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol. Grades: > 95%. CAS No. 171598-74-6. Molecular formula: C19H29NO3. Mole weight: 319.45. | |
| (+)-β-Dihydrotetrabenazine | (+)-β-Dihydrotetrabenazine is a potent inhibitor of vascular monoamine transporter 2 (VMAT2) and an agent of significant interest for therapeutic and molecular imaging applications. Synonyms: (2S,3R,11bR)-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol; (2S,3R,11bR)-Dihydrotetrabe; Tetrabenazine Related Impurity 6(2S,3R,11bR). Grades: ≥95%. CAS No. 924854-60-4. Molecular formula: C19H29NO3. Mole weight: 319.44. | |
| DTR-I | DTR-I is one of Tetrabenazine intermediates. Tetrabenazine is a VMAT-inhibitor used for treatment of hyperkinetic movement disorder. It is a monoamine-depleting and a dopamine-receptor-blocking drug and is an effective and safe drug for the treatment of a variety of hyperkinetic movement disorders. Synonyms: (3R,11bR)-rel-1,3,4,6,7,11b-Hexahydro-9,10-dihydroxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-one; 2H-Benzo[a]quinolizin-2-one, 1,3,4,6,7,11b-hexahydro-9,10-dihydroxy-3-(2-methylpropyl)-, (3R,11bR)-rel-. Grades: ≥95%. CAS No. 2220998-55-8. Molecular formula: C17H23NO3. Mole weight: 289.37. | |
| trans (2,3)-Dihydro Tetrabenazine | A metabolite of Tetrabenazine in vivo. The trans izomer of Dihydrotetrabenazine is used for the treatment of hyperkinetic movement disorders. Group: Biochemicals. Alternative Names: (2R,3R,11bR)-rel-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol; (2α,3 β,11b β)-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol. Grades: Highly Purified. CAS No. 171598-74-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Valbenazine | Valbenazine is a potent and highly selective vesicular monoamine transporter 2(VMAT2) inhibitor. It is a prodrug of the (+)-α isomer of tetrabenazine for tardive syndrome therapy. It is effective in regulating the levels of dopamine release during nerve communication, while at the same time having minimal impact on the other monoamines. It significantly improved tardive dyskinesia and was well tolerated in patients. It is an experimental drug being investigated for use in the treatment of tardive dyskinesia and Tourette syndrome. It was developed by Neurocrine Biosciences. Uses: Valbenazine is an experimental drug being investigated for use in the treatment of tardive dyskinesia and tourette syndrome. Synonyms: Ingrezza; L-Valine, (2R,3R,11bR)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo(a)quinolizin-2-yl ester; (S)-2-amino-3-methyl-butyric acid (2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl ester; Tetrabenazine Related Impurity 28 (2R, 3R, 11bR, L-Val); [(2R,3R,11bR)-9,10-dimethoxy-3-(2-methylpropyl)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-yl] (2S)-2-amino-3-methylbutanoate; NBI-98854; NBI98854; MT-5199; MT5199; NBI 98854; MT 5199. Grades: >98%. CAS No. 1025504-45-3. Molecular formula: C24H38N2O4. Mole weight: 418.57. | |
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