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(E)-Dihydro Efavirenz is an impurity of the nonnucleoside HIV-1 reverse transcriptase inhibitor Efavirenz. Group: Biochemicals. Alternative Names: (4S)-6-Chloro-4-[(1E)-2-cyclopropylethenyl]-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-Benzoxazin-2-one; SR 695. Grades: Highly Purified. CAS No. 440124-96-9. Pack Sizes: 5mg. US Biological Life Sciences.
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(E)-Dihydro Efavirenz
(E)-Dihydro Efavirenz. Uses: For analytical and research use. Group: Impurity standards. CAS No. 440124-96-9. Pack Sizes: 5MG. IUPAC Name: (4S)-6-chloro-4-[(E)-2-cyclopropylethenyl]-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one. Molecular formula: C14H11ClF3NO2. Mole weight: 317.69. Catalog: APS440124969. SMILES: FC(F)(F)[C@]1(OC(=O)Nc2ccc(Cl)cc12)\C=C\C3CC3. Format: Neat. Shipping: Room Temperature.
rac 8,14-Dihydroxy Efavirenz
A metabolite of Efavirenz (secondary metabolism. Group: Biochemicals. Alternative Names: 6-Chloro-1, 4-dihydro-8-hydroxy-4-[ (1-hydroxycyclopropyl) ethynyl]-4- (trifluoromethyl) -2H-3, 1-benzoxazin-2-one. Grades: Highly Purified. CAS No. 1189909-96-3. Pack Sizes: 1mg. US Biological Life Sciences.
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rac 8,14-Dihydroxy Efavirenz-d4
A labeled metabolite of Efavirenz (secondary metabolism. Group: Biochemicals. Alternative Names: 6-Chloro-1,4-dihydro-8-hydroxy-4-[(1-hydroxycyclopropyl-d4)ethynyl]-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one. Grades: Highly Purified. CAS No. 1189859-26-4. Pack Sizes: 1mg. US Biological Life Sciences.
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1,3-Bis(methoxymethyl)-2-nitrobenzene
1,3-Bis(methoxymethyl)-2-nitrobenzene is an intermediate in the synthesis of 2,6-Dihydroxymethyl Rilpivirine (D446615), which is an analog of Rilpivirine (R509800) a novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. An anti-HIV agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 50mg. Molecular Formula: C10H13NO4. US Biological Life Sciences.
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2, 6-Bis (methoxymethyl)aniline
2, 6-Bis (methoxymethyl)aniline is an intermediate in the synthesis of 2,6-Dihydroxymethyl Rilpivirine (D446615), which is an analog of Rilpivirine (R509800) a novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. An anti-HIV agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C10H15NO2. US Biological Life Sciences.
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2-Nitro-1,3-benzenedimethanol
2-Nitro-1,3-benzenedimethanol is an intermediate in the synthesis of 2,6-Dihydroxymethyl Rilpivirine (D446615), which is an analog of Rilpivirine (R509800) a novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. An anti-HIV agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 16578-60-2. Pack Sizes: 50mg, 100mg. Molecular Formula: C8H9NO4. US Biological Life Sciences.
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(4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-2-(4-methoxyphenyl)-4-(trifluoromethyl)-2H-3,1-benzoxazine (Mixture of 2 Diastereomers)
An impurity arising in the synthesis of Efavirenz. Group: Biochemicals. Alternative Names: (4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-2-(4-methoxyphenyl)-4-(trifluoromethyl)-2H-3,1-benzoxazine. Grades: Highly Purified. CAS No. 209414-26-6. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
8-Hydroxy Efavirenz
8-Hydroxy Efavirenz is a metabolite of Efavirenz. Synonyms: (4S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; 8-Hydroxyefavirenz. Grades: > 95%. CAS No. 205754-33-2. Molecular formula: C14H9ClF3NO3. Mole weight: 331.67.
8-(tert-Butyldimethylsilyloxy) 8-hydroxy efavirenz, technical grade. Group: Biochemicals. Alternative Names: 8-(tert-Butyldimethylsilyloxy)-6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; 6-Chloro-4- (2-cyclopropylethynyl) -8-[[ (1, 1-dimethylethyl) dimethylsilyl]oxy]-1, 4-dihydro-4- (trifluoromethyl) -2H-3, 1-benzoxazin-2-one. Grades: Purified. CAS No. 1027042-31-4. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C20H23ClF3NO3Si. US Biological Life Sciences.
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Efavirenz Racemic
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardsimpurity standardspharmaceutical toxicology. Alternative Names: Efavirenz Racemic, ((+/-)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one).
Efavirenz Related Compound B
Efavirenz impurity. Synonyms: (4S)-6-Chloro-4-[(1E)-2-cyclopropylethenyl]-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-Benzoxazin-2-one; USP Efavirenz Related Compound B. Grades: > 95%. CAS No. 440124-96-9. Molecular formula: C14H11ClF3NO2. Mole weight: 317.69.
Ent efavirenz
Ent efavirenz. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (4R)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; (R)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro -4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; L 743725. Product Category: Heterocyclic Organic Compound. Appearance: Off-White to Pale Yellow Solid. CAS No. 154801-74-8. Molecular formula: C14H9ClF3NO2. Mole weight: 315.67. Purity: 0.96. IUPACName: (4R)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one. Density: 1.53g/cm³. Product ID: ACM154801748. Alfa Chemistry ISO 9001:2015 Certified.
rac 7-Hydroxy Efavirenz
A metabolite of Efavirenz (minor). Group: Biochemicals. Alternative Names: 6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-7-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one. Grades: Highly Purified. CAS No. 205754-50-3. Pack Sizes: 500ug, 1mg, 2mg. US Biological Life Sciences.
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rac 7-Hydroxy Efavirenz-d4 (Major)
An isotope labeled metabolite of Efavirenz (minor). A representative lot was 84% d4, 12% d5, 2% d3 and 1% d6. Group: Biochemicals. Alternative Names: 6-Chloro-4-(cyclopropyl-d4-ethynyl)-1,4-dihydro-7-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
rac 8-Hydroxy Efavirenz
A metabolite of Efavirenz , a nonnucleoside HIV-1 reverse transcriptase inhibitor. Synonyms: 6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one. Grades: > 95%. CAS No. 205754-32-1. Molecular formula: C14H9ClF3NO3. Mole weight: 331.68.
rac Efavirenz
rac Efavirenz is a mixture of both enantiomers for Efavirenz. Synonyms: 6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one. Grades: > 95%. CAS No. 177530-93-7. Molecular formula: C14H9ClF3NO2. Mole weight: 315.67.
rac Efavirenz-d4
Labelled Efavirenz (E42500). A nonnucleoside HIV-1 reverse transcriptase inhibitor. Group: Biochemicals. Alternative Names: 6-Chloro-4-(2-cyclopropyl-d4-ethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; DMP 266-d4; L 743726-d4; Stocrin-d4; Sustiva-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
rac Efavirenz-d5 (major)
Labeled Efavirenz. A nonnucleoside HIV-1 reverse transcriptase inhibitor. Group: Biochemicals. Alternative Names: 6-Chloro-4-(2-cyclopropyl-d5-ethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; DMP 266-d5; L 743726-d5. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
An intermediate in the synthesis of Efavirenz-d4. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Efavirenz (Sustiva, MDP-266, L-743726)
A nonnucleoside HIV-1 reverse transcriptase inhibitor. Group: Biochemicals. Alternative Names: (4S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; DMP 266; L 743726; Stocrin; Sustiva. Grades: Highly Purified. CAS No. 154598-52-4. Pack Sizes: 250mg, 500mg, 1g. Molecular Formula: C14H9ClF3NO2, Molecular Weight: 315.67. US Biological Life Sciences.
Worldwide
ent-Efavirenz
A nonnucleoside HIV-1 reverse transcriptase inhibitor. Antiviral. Group: Biochemicals. Alternative Names: (4R)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; (R)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; L 743725. Grades: Highly Purified. CAS No. 154801-74-8. Pack Sizes: 2.5mg. US Biological Life Sciences.
An impurity of Rilmenidine,Rilmenidine Is A novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. An anti-HIV agent. Grades: > 95%. Molecular formula: C11H8N4O. Mole weight: 212.21.
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are highly specific and potent allosteric inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. Efavirenz is an NNRTI that prevents RNA plus-strand initiation with an IC50 value of 17 nM. Efavirenz also inhibits the late stages of HIV-1 replication by interfering with HIV-1 Gag-Pol polyprotein processing. It has been used in combination therapy with drugs directed at the treatment of opportunistic infections such as HIV and cancer. Synonyms: (4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one. Grades: > 98 %. CAS No. 154598-52-4. Molecular formula: C14H9ClF3NO2. Mole weight: 315.67.
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