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1,4-Diaminobutane is an amino acid degradation product. Used in the preparation of hexahydropyrimidines as novel hepatitis C virus inhibitors. Also a reagent in the synthesis of antibacterial castor oil-based polyurethane membranes. Group: Biochemicals. Grades: Highly Purified. CAS No. 110-60-1. Pack Sizes: 10g, 25g. Molecular Formula: C4H12N2. US Biological Life Sciences.
13C Labeled Compounds. Alternative Names: Purescine 13C4; Diaminobutane 13C4. CAS No. 1173023-66-9. Molecular formula: 13C4H12N2. Mole weight: 92.12. Catalog: ACM1173023669.
1,4-Diaminobutane-13C4
1,4-Diaminobutane-13C4 is the isotope labelled analog of 1,4-Diaminobutane (D416025); an amino acid degradation product used in the preparation of hexahydropyrimidines as novel hepatitis C virus inhibitors. Also a reagent in the synthesis of antibacterial castor oil-based polyurethane membranes. Group: Biochemicals. Grades: Highly Purified. CAS No. 1173023-66-9. Pack Sizes: 1mg, 10mg. Molecular Formula: 13C4H12N2, Molecular Weight: 92.12. US Biological Life Sciences.
It is an NMDA receptor agonist produced by the breakdown of amino acids after the death of an organism. It is a polyamine plant growth regulator affecting the synthesis of macromolecules and the development of root systems in plants. Uses: Used in biochemical research. Synonyms: 1,4-Butanediamine Dihydrochloride; Putrescine Dihydrochloride; Putrescine Hydrochloride; Tetramethylenediamine Dihydrochloride. Grades: ≥ 98 %. CAS No. 333-93-7. Molecular formula: C4H12N2.2HCl. Mole weight: 161.07.
We offer a diverse selection of dendrimers containing a large number of peripheral groups. Uses: They adopt nanometer-scale dimensions, and can be ideal candidates for drug delivery, gene transfection applications. Group: Dendrimers. Pack Sizes: 2 g in glass bottle unit weight includes solvent. Molecular formula: 1457.90. Mole weight: [NH2(CH2)4NH2]:(G=1);dendri PAMAM(NH2)8.
We offer a diverse selection of dendrimers containing a large number of peripheral groups. Uses: They adopt nanometer-scale dimensions, and can be ideal candidates for drug delivery, gene transfection applications. Group: Dendrimers. Pack Sizes: 2 g in glass bottle unit weight includes solvent. Molecular formula: 58074.17. Mole weight: [NH2(CH2)4NH2]:(G=6);dendri PAMAM(NH2)256.
We offer a diverse selection of dendrimers containing a large number of peripheral groups. Uses: They adopt nanometer-scale dimensions, and can be ideal candidates for drug delivery, gene transfection applications. Group: Dendrimers. Alternative Names: PAMAM-G4-COOH. Pack Sizes: 1 g in poly bottle unit weight includes solvent. Molecular formula: 20646.87. Mole weight: [NH2(CH2)4NH2]:(G=4);dendri PAMAM(NHCOCH2CH2COOH)64.
We offer a diverse selection of dendrimers containing a large number of peripheral groups. Uses: They adopt nanometer-scale dimensions, and can be ideal candidates for drug delivery, gene transfection applications. Group: Dendrimers. Pack Sizes: 1 g in poly bottle unit weight includes solvent. Molecular formula: 41662.18. Mole weight: [NH2(CH2)4NH2]:(G=5);dendri PAMAM(NHCOCH2CH2COOH)128.
25g Pack Size. Group: Bioactive Small Molecules, Building Blocks, Research Organics & Inorganics. Formula: NH2(CH2)4NH2 · 2HCl. CAS No. 333-93-7. Prepack ID 25523156-25g. Molecular Weight 161.07. See USA prepack pricing.
Trityl-1,4-diaminobutane acetate. Group: Biochemicals. Alternative Names: Trt-NH(CH2)4NH2 ·AcOH. Grades: Highly Purified. CAS No. 189341-61-5. Pack Sizes: 2g, 5g, 10g, 25g. US Biological Life Sciences.
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Trityl-1,4-diaminobutane acetate ≥97%
Trityl-1,4-diaminobutane acetate ≥97%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
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Z-1,4-diaminobutane HCl
Z-1,4-diaminobutane HCl (CAS# 18807-73-3) is used in the synthetic preparation of pyrazolyl glucopyranoside and galactopyranoside derivative inhibitors of human sodium-glucose cotransporter 1 (SGLT1) for preventives or therapeutics for diseases related to hyperglycemia or galactosemia. Synonyms: N-1-Z-1,4-diaminobutane HCl; benzyl 4-aminobutylcarbamate Hydrochloride (1:1); N-benzyloxycarbonyl-1,4-diaminobutane Hydrochloride (1:1); N-Cbz-1,4-diaminobutane Hydrochloride (1:1); N-carbobenzoxy 1,4-diaminobutane Hydrochloride (1:1); 4-benzyloxycarbonylamino-1-butylamine Hydrochloride (1:1); Z-putrescine HCl; (4-aminobutyl)carbamic Acid, Benzyl Ester, Monohydrochloride; (4-aminobutyl)-carbamic Acid, Phenylmethyl Ester Monohydrochloride. Grades: ≥95%. CAS No. 18807-73-3. Molecular formula: C12H18N2O2.HCl. Mole weight: 258.75.
Z-1,4-diaminobutane·HCl
Z-1,4-diaminobutane·HCl. Group: Biochemicals. Alternative Names: Z-NH(CH2)4NH2·HCl. Grades: Highly Purified. CAS No. 18807-73-3. Pack Sizes: 1g, 2g, 5g, 10g, 25g. US Biological Life Sciences.
Worldwide
Z-1,4-diaminobutane·HCl 99+% (HPLC)
Z-1,4-diaminobutane·HCl 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
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1,4-Butane-1,1,2,2,3,3,4,4-d8-diamine
1,4-Butane-1,1,2,2,3,3,4,4-d8-diamine (D416027) is a labelled isotope of 1,4-Diaminobutane (D416025). It is an amino acid degradation product. Used in the preparation of hexahydropyrimidines as novel hepatitis C virus inhibitors. Also a reagent in the synthesis of antibacterial castor oil-based polyurethane membranes. Group: Biochemicals. Grades: Highly Purified. CAS No. 709608-92-4. Pack Sizes: 10mg, 25mg. Molecular Formula: C4H4D8N2. US Biological Life Sciences.
Worldwide
4- (Diethylamino) butylamine
4- (Diethylamino) butylamine. Group: Biochemicals. Alternative Names: N,N-Diethyl-1,4-butanediamine; 4- (N, N-Diethylamino) butylamine; N,N-Diethyl-1,4-diaminobutane; N, N-Diethyltetra methyl enediamine. Grades: Highly Purified. CAS No. 27431-62-5. Pack Sizes: 100mg. Molecular Formula: C8H20N2, Molecular Weight: 144.26. US Biological Life Sciences.
1,4-Diaminobutane is known to affect the development of plant root systems, its inhibition resulting in a more dominant tap root system. 1,4-Diaminobutane is an amino acid degradation product. Used in the preparation of hexahydropyrimidines as novel hepatitis C virus inhibitors. Also a reagent in the synthesis of antibacterial castor oil-based polyurethane membranes. Group: Biochemicals. Alternative Names: 1,4-Butanediamine Dihydrochloride; 1,4-Diaminobutane Dihydrochloride; Putrescine Dihydrochloride; Putrescine Hydrochloride; Tetramethylenediamine Dihydrochloride. Grades: Highly Purified. CAS No. 333-93-7. Pack Sizes: 25g, 100g, 250g, 500g, 1Kg. Molecular Formula: C?H??Cl?N?. US Biological Life Sciences.
Worldwide
Spermidine
Spermidine is a polyamine compound found in ribosomes and living tissues, and having various metabolic functions within organisms. It was originally isolated from semen. Synonyms: N1-(3-Aminopropyl)-1,4-butanediamine; N-(3-Aminopropyl)-1,4-butanediamine; 1,5,10-Triazadecane; 1,8-Diamino-4-azaoctane; 4-Azaoctane-1,8-diamine; N-(3-Aminopropyl)-1,4-diaminobutane; N-(3-Aminopropyl)-4-aminobutylamine; N-(4-Aminobutyl)-1,3-diaminopropane; Spermidin. Grades: > 95%. CAS No. 124-20-9. Molecular formula: C7H19N3. Mole weight: 145.25.
Spermidine Free Base
Biogenic polyamine formed from putrescine, a precursor of spermine; essential for normal and neoplastic tissue growth, promoting T4 polynucleotide kinase. Acts as a neuronal nitric oxide synthetase inhibitor. Used in cancer research and cell culture media. Group: Biochemicals. Alternative Names: N1-(3-Aminopropyl)-1,4-butanediamine; N-(3-Aminopropyl)-1,4-butanediamine; 1,5,10-Triazadecane; 1,8-Diamino-4-azaoctane; 4-Azaoctane-1,8-diamine; N-(3-Aminopropyl)-1,4-diaminobutane; N-(3-Aminopropyl)-4-aminobutylamine; N-(4-Aminobutyl)-1,3-diaminopropane; Spermidin. Grades: Molecular Biology Grade. CAS No. 124-20-9. Pack Sizes: 1g, 5g, 25g. Molecular Formula: C?H??N?, Molecular Weight: 145.25. US Biological Life Sciences.
Worldwide
Spermine
Spermine (NSC 268508) functions directly as a free radical scabenger to protect DNA from free radical attack. Spermine has antiviral effects. Group: Inhibitors. Alternative Names: 1,4-Bis(aminopropyl)butanediamine;1,4-Butanediamine, N,N-bis(3-aminopropyl)-;1,4-Diaminobutane, N,N-bis(3-aminopropyl)-;4,9-Diaza-1,12-dodecanediamine;4,9-Diazadodecane-1,12-diamine;n,n'-bis(3-aminopropyl)-4-butanediamine;n,n'-bis(3-aminopropyl)-4-diaminobutane;Spermin. CAS No. 71-44-3. Molecular formula: C10H26N4. Mole weight: 202.34. Appearance: powder. Purity: 0.9836. Catalog: ACM71443.
3,4-Diaminobutanoic acid dihydrochloride
3,4-Diaminobutanoic acid dihydrochloride, a chemical entity employed in biomedicine, has been found to exhibit promise in the management of select neurological conditions. Furthermore, it has been identified to have potential utility in the therapeutic addressing of several inherited metabolic ailments characterized by augmented homocysteine concentrations in the bloodstream, including but not restricted to, homocystinuria. Moreover, its synthetic applications extend beyond the medical arena and encompass its involvement in the assembly of certain antibiotics and its role as a reagent in chemical synthesis. CAS No. 109754-82-7. Molecular formula: C4H12Cl2N2O2. Mole weight: 191.05.
Colistin B
It is produced by the strain of Bacillus polymyxa var. colistinus and Bac. colistinum Koyama 70-B. It has good anti-gram-negative bacterial activity, but has poor effect on Pseudomonas aeruginosa and Proteus aeruginosa. Colistin B is used as an antibiotic in the treatment of infectious diseases resulting from multi-drug resistant (MDR) gram-negative bacteria. Synonyms: Polymyxin E2; Colistin b; 4,10-anhydro[N-(6-methylheptanoyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-leucyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine]. Grades: ≥ 95%. CAS No. 7239-48-7. Molecular formula: C52H98N16O13. Mole weight: 1155.43.
Requires Na+ or K+ for maximal activity. Ornithine, lysine, aspartate, and α-,β- and γ-aminobutanoate cannot act as substrates. However, acetyl-CoA can be replaced by propanoyl-CoA, although the reaction proceeds more slowly. Forms part of the ectoine-biosynthesis pathway, the other enzymes involved being EC 2.6.1.76, diaminobutyrate-2-oxoglutarate transaminase and EC 4.2.1.108, ectoine synthase. Group: Enzymes. Synonyms: L-2,4-diaminobutyrate acetyltransferase; L-2,4-diaminobutanoate acetyltransferase; EctA; diaminobutyric acid acetyltransferase; DABA acetyltransferase; 2,4-diaminobutanoate acetyltransferase; DAB acetyltransferase; DABAcT; acetyl-CoA:L-2,4-diaminobutanoate 4-N-acetyltransferase. Enzyme Commission Number: EC 2.3.1.178. CAS No. 130456-92-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2119; diaminobutyrate acetyltransferase; EC 2.3.1.178; 130456-92-7; L-2,4-diaminobutyrate acetyltransferase; L-2,4-diaminobutanoate acetyltransferase; EctA; diaminobutyric acid acetyltransferase; DABA acetyltransferase; 2,4-diaminobutanoate acetyltransferase; DAB acetyltransferase; DABAcT; acetyl-CoA:L-2,4-diaminobutanoate 4-N-acetyltransferase. Cat No: EXWM-2119.
H-DL-Dab 2HCl
A racemic mixture of selective GABA uptake inhibitors L-DABA and D-DABA. Synonyms: DL-2,4-Diaminobutyric acid dihydrochloride; 2,4-diaminobutanoic acid dihydrochloride. Grades: ≥ 98% (Titration). CAS No. 65427-54-5. Molecular formula: C4H10N2O2·2HCl. Mole weight: 191.05.
L-DABA
L-DABA, (L-2,4-Diaminobutyric acid) is a noncompetitive GABA transaminase inhibitor (IC50 > 500 μM) with antitumor activity in vivo and in vitro. Synonyms: (2S)-2,4-diaminobutanoic acid; 2,4-diaminobutyric acid; 2,4-diaminobutyric acid dihydrochloride, (+-)-isomer; 2,4-diaminobutyric acid dihydrochloride, (S)-isomer; 2,4-diaminobutyric acid monohydrochloride, (+-)-isomer; 2,4-diaminobutyric acid monohydrochloride, (S)-isomer; 2,4-diaminobutyric acid, (+)-isomer; 2,4-diaminobutyric acid, (+-)-isomer; 2,4-diaminobutyric acid, (R)-isomer; 2,4-diaminobutyric acid, (S)-isomer; L-2,4-diaminobutyric acid. CAS No. 1758-80-1. Molecular formula: C4H10N2O2. Mole weight: 118.13.
Lei-Dab 7
HLei-Dab 7 is a calcium-activated potassium channel blocker. Synonyms: L-alanyl-L-phenylalanyl-L-cysteinyl-L-asparaginyl-L-leucyl-L-arginyl-(2S)-2,4-diaminobutanoyl-L-cysteinyl-L-glutaminyl-L-leucyl-L-seryl-L-cysteinyl-L-arginyl-L-seryl-L-leucylglycyl-L-leucyl-L-leucylglycyl-L-lysyl-L-cysteinyl-L-isoleucylglycyl-L-α-aspartyl-L-lysyl-L-cysteinyl-L-α-glutamyl-L-cysteinyl-L-valyl-L-lysyl-L-Histidinamide-cyclic (3?21)-(8?26)-(12?28)-tris(disulfide). Grades: ≥97%. CAS No. 1061556-49-7. Molecular formula: C141H236N46O39S6. Mole weight: 3392.06.
Octapeptin C1
It is a peptide antibiotic produced by the strain of Bacillus circulans 333-25. It has anti-gram-positive and gram-negative bacteria activity, but no effect on pseudomonas aeruginosa. It inhibits E. coli and Klebsiella pneumoniae with IC50 of 0.95 mg/kg (Mice, subcutaneous). Synonyms: Antibiotic 333-25; Octapeptin A1, 1-(N(sup 2)-(3-hydroxy-6-methyl-1-oxooctyl)-D-2,4-diaminobutanoic acid)-4-D-phenylalanine-; N2-[N2-(3-Hydroxy-6-methyl-1-oxooctyl)-D-DAB-]cyclo[L-DAB*-L-DAB-D-Phe-L-Leu-L-DAB-L-DAB-L-Leu-]. CAS No. 59217-95-7. Molecular formula: C50H87N13O10. Mole weight: 1030.31.
PE1
PE1 is an antimicrobial peptide isolated from Paenibacillus ehimensis B7. It has anti-gram-positive bacteria, gram-negative bacteria and fungal activity. It is an N-terminal lipidated cyclic antibiotic with nonstandard amino acid Dab at positions 1, 3, and 6 (Warning: Dab, 2,4-diaminobutanoic acid, is two CH2 units less than lysine, although represented by K here in the sequence), D-amino acids for F4 and V7. The ring structure is proposed to occur between the C-terminal carboxylic and hydroxyl group of the N-terminal fatty acid portion. Synonyms: cyclo{CH(n-butyl)-CH2-CO-L-Dab-Ile-Dab-D-Phe-Leu-Dab-D-Val-Leu-Thr}; Paenibacillus ehimensis 1. Grades: ≥96%. Molecular formula: C55H94N12O12. Mole weight: 1115.43.
PE2
PE2 is an antimicrobial peptide isolated from Paenibacillus ehimensis B7. It has anti-gram-positive bacteria, gram-negative bacteria and fungal activity. It is an N-terminal lipidated cyclic antibiotic with nonstandard amino acid Dab at positions 1, 3, and 6 (Warning: Dab, 2,4-diaminobutanoic acid, is two CH2 units less than lysine, although represented by K here in the sequence), D-amino acids for F4 and V7. The ring structure is proposed to occur between the C-terminal carboxylic and hydroxyl group of the N-terminal fatty acid portion. Synonyms: cyclo{CH(n-propyl)-CH2-CO-L-Dab-Ile-Dab-D-Phe-Leu-Dab-D-Val-Leu-Thr}; Paenibacillus ehimensis 2. Grades: ≥95%. Molecular formula: C54H92N12O12. Mole weight: 1101.40.
Polymyxin B1
Polymyxin B1. Group: Biochemicals. Alternative Names: N2-(6-Methyl-1-oxooctyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-phenylalanyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine Cyclic (10?4)-Peptide. Grades: Highly Purified. CAS No. 4135-11-9. Pack Sizes: 2.5mg. Molecular Formula: C56H98N16O13, Molecular Weight: 1203.48. US Biological Life Sciences.
Worldwide
Polymyxin B1
Polymyxin B1 is a cyclic peptide antibiotic of Bacillus polymyxa. The effect of anti-gram-negative bacteria is greater than that of anti-gram-positive bacteria. Synonyms: 4,10-anhydro{N-[(6R)-6-methyloctanoyl]-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-phenylalanyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine}; polymycin B. Grades: ≥95%. CAS No. 4135-11-9. Molecular formula: C56H98N16O13. Mole weight: 1203.47.
Polymyxin B1 Sulfate
It is produced by the strain of Pseudomonas sp. It is one of the polypeptide fractions in polymyxin B sulfate. Polymyxin B1 is an antibacterial compound. It has a high volume of distribution and longer elimination half-life in patients with multidrug-resistant gram-negative bacterial infection. Synonyms: Polymyxin B1 sulfate salt (1:1); N2-(6-Methyl-1-oxooctyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-phenylalanyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine Cyclic (10?4)-Peptide sulfate (1:1). Grades: >90.0%. CAS No. 108965-61-3. Molecular formula: C56H98N16O13.H2SO4. Mole weight: 1301.55.
Polymyxin B nonapeptide
Polymyxin B nonapeptide interacts with the outer membrane of gram-negative bacteria to increase the permeability of the membrane by promoting hydrophobic diffusion. Synonyms: Polymyxin B Cyclononapeptide; Polymyxin B1, 1-De(N2-(6-Methyl-1-Oxooctyl)-L-2,4-Diaminobutanoic Acid)-; PMBN; T-Dab-Dab-Dab-Dab-d-FL-Dab-Dab-T (Lactam: Dab3-Thr9); N2-(L-Thr-L-A2bu-)Cyclo(L-A2bu*-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-L-Thr-); Nα-(L-Thr-L-A2bu-)Cyclo(L-A2bu*-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-L-Thr-). Grades: ≥95%. CAS No. 86408-36-8. Molecular formula: C43H74N14O11. Mole weight: 963.13.
Polymyxin B nonapeptide acetate
Polymyxin B nonapeptide acetate is a cationic cyclic peptide that interacts with the outer membrane of gram-negative bacteria to increase the permeability of the membrane by promoting hydrophobic diffusion. Synonyms: H-Thr-Dab-Dab-Dab-D-Phe-Leu-Dab-Dab-Thr.CH3CO2H (Disulfide bridge: Cys3-Cys9); Polymyxin B1, 1-de[N2-(6-methyl-1-oxooctyl)-L-2,4-diaminobutanoic acid]-, acetate; 2-10-Polymyxin B1 acetate. Grades: ≥95%. Molecular formula: C45H78N14O13. Mole weight: 1023.19.
Polymyxin E1 Sulfate
It is produced by the strain of Bacillus polymyxa var. colistinus. Polymyxin E1 Sulfate is sulfate salt form of Polymyxin E1, which is used as an antibiotic in the treatment of infectious diseases resulting from multi-drug resistant (MDR) gram-negative bacteria. Synonyms: Colistin A Sulfate; Polymixin E1 Sulfate salt; Colistin IV Sulfate; N2-(6-Methyl-1-oxooctyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-leucyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine Cyclic (10?4)-Peptide Sulfate. Grades: ≥90.0% by HPLC. Molecular formula: C53H100N16O13.xH2SO4. Mole weight: 1169.46 (free base).
Polymyxin E2 Sulfate
It is produced by the strain of Bacillus polymyxa var. colistinus. Polymyxin E2 Sulfate is sulfate salt form of Polymyxin E2, which is used as an antibiotic in the treatment of infectious diseases resulting from multi-drug resistant (MDR) gram-negative bacteria. Synonyms: Colistin B Sulfate Salt; Polymyxin E2 Sulfate Salt; 1-[(2S)-4-Amino-2-[(6-methyl-1-oxoheptyl)amino]butanoic acid]polymyxin E1 Sulfate Salt; Colistin I Sulfate Salt; N2-(6-Methyl-1-oxoheptyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-leucyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine (10?4)-Lactam Sulfate Salt. Grades: ≥90.0% by HPLC. CAS No. 1338055-88-1. Molecular formula: C52H98N16O13.xH2SO4. Mole weight: 1155.43 (free base).
It is an antibiotic with antimicrobial properties produced by the strain of Bacillus polymyxa AR-110. Synonyms: D-2,4-diaminobutanoylglycyl-Dseryl-D-tryptophyl-L-seryl-L-2,4-diaminobutanoyl-D-2,4-diaminobutanoyl-L-phenylalanyl-L-r-glutamyl-L-valyl-Dalloisoleucyl. CAS No. 67922-28-5. Molecular formula: C73H115N17O20. Mole weight: 1550.79.
Tyr-(D-Dab4,Arg5,D-Trp8)-cyclo-Somatostatin-14 (4-11), a high affinity ligand of five somatostatin receptors (SST1-SST5), has higher binding affinity than omatostatin-14 and octreotide in AtT-20 mouse anterior pituitary tumor cells expressing SST2 and SST5 receptors. Synonyms: KE 108; H-Tyr-cyclo(-D-Dab-Arg-Phe-Phe-D-Trp-Lys-Thr-Phe); L-Tyrosyl-(2R)-2,4-diaminobutanoyl-L-arginyl-L-phenylalanyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-phenylalanine (9?2)-lactam; Benzenepropanamide, α-amino-N-[(3S,6S,9S,12R,15S,18S,21S,24R)-9-(4-aminobutyl)-21-[3-[(aminoiminomethyl)amino]propyl]-6-[(1R)-1-hydroxyethyl]-12-(1H-indol-3-ylmethyl)-2,5,8,11,14,17,20,23-octaoxo-3,15,18-tris(phenylmethyl)-1,4,7,10,13,16,19,22-octaazacyclohexacos-24-yl]-4-hydroxy-, (αS)-. Grades: 95%. CAS No. 496849-46-8. Molecular formula: C67H85N15O11. Mole weight: 1276.49.
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