Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| 2-(1-Piperazinyl)pyrimidine | 2-(1-Piperazinyl)pyrimidine is the major metabolite of Tandospirone (HY-14558) [1]. Uses: Scientific research. Group: Natural products. CAS No. 20980-22-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-W004464. |  |
| 2-(1-Piperazinyl)pyrimidine | 2- (1-Piperazinyl) pyrimidinejor metabolite of Tandospirone. Group: Biochemicals. Alternative Names: 1- (2-Pyrimidinyl) piperazine. Grades: Highly Purified. CAS No. 20980-22-7. Pack Sizes: 1g. US Biological Life Sciences. |  Worldwide |
| 2-(1-Piperazinyl)pyrimidine | 2-(1-Piperazinyl)pyrimidine. Uses: For analytical and research use. Group: Impurity standards. CAS No. 20980-22-7. Pack Sizes: 1G. IUPAC Name: 2-piperazin-1-ylpyrimidine. Molecular formula: C8H12N4. Mole weight: 164.21. Catalog: APS20980227. SMILES: C1CN(CCN1)c2ncccn2. Format: Neat. Shipping: Room Temperature. |  |
| 2-(1-Piperazinyl)pyrimidine (Standard) | 2-(1-Piperazinyl)pyrimidine (Standard) is the analytical standard of 2-(1-Piperazinyl)pyrimidine. This product is intended for research and analytical applications. 2-(1-Piperazinyl)pyrimidine is the major metabolite of Tandospirone (HY-14558) [1]. Uses: Scientific research. Group: Natural products. CAS No. 20980-22-7. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-W004464R. | |
| 5-Benzyloxy-2-(1-piperazinyl)pyrimidine | Intermediate used in the preparation of CNS agents. Group: Biochemicals. Alternative Names: 5-(Phenylmethoxy)-2-(1-piperazinyl)-pyrimidine. Grades: Highly Purified. CAS No. 87789-61-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Ketohexokinase Inhibitor (N8-(Cyclopropylmethyl)-N4-(2-(methylthio)phenyl)-2-(1-piperazinyl)-pyrimido[5,4-d]pyrimidine-4,8-diamine, KHK Inhibitor) | An orally bioavailable pyrimidinopyrimidine compound that acts as a potent, reversible and ATP-competitive inhibitor of human hepatic KHK activity (KHK-C isoform; IC50=12nM in a transcreener ADP assay) and efficiently blocks fructose-1-phosphate secretion (IC50 ≤ 400nM in HepG2 cells). Displays ~50-fold lower potency towards metabolic kinases, namely, ribokinase, hexokinase and adenosine kinase, and minimal binding affinities to diverse receptors and ion-channels, and excellent selectivity among a panel of 31-kinases including Akt1, AMPK, CaMKI/II, InsR, IRAK4, PKA and PKCtheta (IC50 >> 10uM). Shown to minimally affect the activities of human cytochrome p450 isozymes (1A2, 2C19, 2D6, 2C9 and 3A4), and exhibit high volume of distribution and high rate of clearance in rats. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?S 2HCl. US Biological Life Sciences. | Worldwide |
| 5-? [2-?Ethoxy-?5-? [ (4-?methyl-?1-?piperazinyl) ?thioxomethyl] ?phenyl] ?-?1, ?6-?dihydro-?1-?methyl-?3-?propyl-7H-?pyrazolo [4, ?3-?d] ?pyrimidine-?7-?thione | 5-? [2-?Ethoxy-?5-? [ (4-?methyl-?1-?piperazinyl) ?thioxomethyl] ?phenyl] ?-?1, ?6-?dihydro-?1-?methyl-?3-?propyl-7H-?pyrazolo [4, ?3-?d] ?pyrimidine-?7-?thione. Group: Biochemicals. Alternative Names: 5-[2-Ethoxy-5-[ (4-methyl-1-piperazinyl) thioxomethyl]phenyl]-1, 6-dihydro-1-methyl-3-propyl-7H-Pyrazolo[4, ?3-?d]pyrimidine-7-thione; Dithiodes methyl carbodenafil. Grades: Highly Purified. CAS No. 1333233-46-7. Pack Sizes: 10mg. Molecular Formula: C23H30N6OS2, Molecular Weight: 470.65. US Biological Life Sciences. | Worldwide |
| 5-Ethyl-2-(piperazin-1-yl)pyrimidine | 5-Ethyl-2-(piperazin-1-yl)pyrimidine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AGN-PC-03JOJ8, SCHEMBL714929, 1-(5-ethyl-2-pyrimidinyl)piperazine, 5-ethyl-2-piperazin-1-yl-pyrimidine, AKOS015966556, 1-(5-ethyl-2-pyrimidinyl) piperazine, Pyrimidine, 5-ethyl-2-(1-piperazinyl)-, AJ-122826, 4-(5-ethyl-pyrimidin-2-yl)-piperazin-1-yl, 501126-09-6. Product Category: Heterocyclic Organic Compound. CAS No. 501126-09-6. Molecular formula: C10H16N4. Mole weight: 192.260840 [g/mol]. Purity: 0.96. IUPACName: 5-ethyl-2-piperazin-1-ylpyrimidine. Product ID: ACM501126096. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Desmethyl Thiosildenafil | Sildenafil thiono analog, a novel pyrazolopyrimidinethio nes as PDE5 inhibitor. Group: Biochemicals. Alternative Names: 5-[2-Ethoxy-5- (1-piperazinylsulfonyl) phenyl]-1, 6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4, 3-d]pyrimidine-7-thione. Grades: Highly Purified. CAS No. 479073-86-4. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Desmethyl Thiosildenafil-d8 | Labeled Sildenafil thiono analog, a novel pyrazolopyrimidinethio nes as PDE5 inhibitor. Group: Biochemicals. Alternative Names: 5-[2-Ethoxy-5-(1-piperazinyl-d8-sulfonyl)phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidine-7-thione. Grades: Highly Purified. CAS No. 1215321-44-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Pipemidic acid | Pipemidic acid. Group: Biochemicals. Alternative Names: 8-Ethyl-5,8-dihydro-5-oxo-2-(1-piperazinyl)pyrido(2,3-d)pyrimidine-6-carboxylic acid. Grades: Highly Purified. CAS No. 51940-44-4. Pack Sizes: 10g, 25g, 50g, 100g. Molecular Formula: C14H17N5O3. US Biological Life Sciences. | Worldwide |
| Pipemidic Acid Trihydrate | An antibacterial agent that is effective againts garam negative bacteria such as Pseudomonas Aeruginosa as well as some gram positive bacteria. Group: Biochemicals. Alternative Names: 8-Ethyl-5,8-dihydro-5-oxo-2-(1-piperazinyl)pyrido[2,3-d]pyrimidine-6-carboxylic Acid Trihydrate. Grades: Highly Purified. CAS No. 72571-82-5. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| 5-[6-[4- (1-Piperazinyl) phenyl]pyrazolo[1, 5-a]pyrimidin-3-yl]quinoline | 5-[6-[4- (1-Piperazinyl) phenyl]pyrazolo[1, 5-a]pyrimidin-3-yl]quinoline. Group: Biochemicals. Alternative Names: LDN 212854. Grades: Highly Purified. CAS No. 1432597-26-6. Pack Sizes: 5mg. Molecular Formula: C25H22N6, Molecular Weight: 406.48. US Biological Life Sciences. | Worldwide |
| 6-Desacetyl Palbociclib | An impurity of Palbociclib, a selective inhibitor of cyclin-dependent kinases CDK4 and CDK6. Palbociclib is developed for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: Pyrido[2,3-d]pyriMidin-7(8H)-one, 8-cyclopentyl-5-Methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]aMino]-; Pyrido-[2,3-d]-pyrimidin-7-one 38. CAS No. 571190-22-2. Molecular formula: C22H27N7O. Mole weight: 405.506. |  |
| 8-cyclopentyl-5-methyl-2,6-bis((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one | An impurity of Palbociclib which is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: Pyrido[2,3-d]pyrimidin-7(8H)-one, 8-cyclopentyl-5-methyl-2,6-bis[[5-(1-piperazinyl)-2-pyridinyl]amino]; Palbociclib Impurity G. CAS No. 2458234-37-0. Molecular formula: C31H39N11O. Mole weight: 581.73. | |
| Abemaciclib metabolite M2 | Abemaciclib metabolite M2, a metabolite of Abemaciclib, is a potent inhibitor of CDK4 and CDK6 with IC50s of 1-3 nM. It has anticancer activity. Synonyms: LSN2839567; 5-Fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzimidazol-6-yl)-N-[5-(1-piperazinylmethyl)-2-pyridinyl]-2-pyrimidinamine; 2-Pyrimidinamine, 5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-N-[5-(1-piperazinylmethyl)-2-pyridinyl]-. Grade: ≥95%. CAS No. 1231930-57-6. Molecular formula: C25H28F2N8. Mole weight: 478.54. | |
| CTX-0294885 | CTX-0294885 is a novel broad-spectrum kinase inhibitor. CTx-0294885 exhibits inhibitory activity against a broad range of kinases in vitro. Use of a quantitative proteomics approach confirmed the selectivity of CTx-0294885-bound beads for kinase enrichment. Large-scale CTx-0294885-based affinity purification followed by LC-MS/MS led to the identification of 235 protein kinases from MDA-MB-231 cells, including all members of the AKT family that had not been previously detected by other broad-spectrum kinase inhibitors. CTx-0294885 represents a powerful new reagent for analysis of kinome signaling networks that may facilitate development of targeted therapeutic strategies. Synonyms: CTX 0294885; CTX0294885; Benzamide, 2-[[5-chloro-2-[[4-(1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]-N-methyl-. Grade: 98%. CAS No. 1439934-41-4. Molecular formula: C22H24ClN7O. Mole weight: 437.93. | |
| Ldn193189 | Ldn193189. Uses: Designed for use in research and industrial production. Additional or Alternative Names: S2618_Selleck; cc-233; UNII-W69H5YQU9O; 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline hydrochloride DM-3189. Appearance: solid. CAS No. 1062368-24-4. Molecular formula: C25H22N6. Mole weight: 406.48. Purity: 98%+. IUPACName: 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline. Canonical SMILES: C1CN(CCN1)C2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC6=CC=CC=C56)N=C3. Product ID: ACM1062368244. Alfa Chemistry ISO 9001:2015 Certified. | |
| N-Desethyl Acetildenafil | A pyrazolopyrimidinone derivative as cGMP phosphodiesterase inhibitor. Group: Biochemicals. Alternative Names: 5-[2-Ethoxy-5- (1-piperazinylacetyl) phenyl]-1, 4-dihydro-1-methyl-3-propyl-7H-pyrazolo[4, 3-d]pyrimidin-7-one. Grades: Highly Purified. CAS No. 147676-55-9. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| N-Desethyl Acetildenafil-d8 Dihydrochloride | A labeled pyrazolopyrimidinone derivative as cGMP phosphodiesterase inhibitor. Group: Biochemicals. Alternative Names: 5-[2-Ethoxy-5-(1-piperazinyl-d8-acetyl)phenyl]-1,4-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one Dihydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| N-Deshydroxyethyl dasatinib | N-Deshydroxyethyl dasatinib. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-(2-Chloro-6-methylphenyl)-2-[[2-methyl-6-(1-piperazinyl)-4-pyrimidinyl]amino]-5-thiazolecarboxamide;N-Deshydroxyethyl Dasatinib;Dasatinib metabolite M4. Product Category: Heterocyclic Organic Compound. Appearance: White to Off-White Solid. CAS No. 910297-51-7. Molecular formula: C20H22ClN7OS. Product ID: ACM910297517. Alfa Chemistry ISO 9001:2015 Certified. | |
| N-Deshydroxyethyl Dasatinib | A metabolite of Dasatinib. Used in the treatment of cancers and immune diseases. Group: Biochemicals. Alternative Names: N-(2-Chloro-6-methylphenyl)-2-[[2-methyl-6-(1-piperazinyl)-4-pyrimidinyl]amino]-5-thiazolecarboxamide; Dasatinib metabolite M4. Grades: Highly Purified. CAS No. 910297-51-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| N-Deshydroxyethyl Dasatinib-d8 | A labeled metabolite of Dasatinib. Used in the treatment of cancers and immune diseases. Group: Biochemicals. Alternative Names: N-(2-Chloro-6-methylphenyl)-2-[[2-methyl-6-(1-piperazinyl-d8)-4-pyrimidinyl]amino]-5-thiazolecarboxamide; Dasatinib Metabolite M4-d8. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| N-Deshydroxyethyl Dasatinib-[d8] | N-Deshydroxyethyl Dasatinib-[d8] is the labelled analogue of N-Deshydroxyethyl Dasatinib, which is a metabolite of Dasatinib. Synonyms: N-Deshydroxyethyl Dasatinib D8; N-(2-Chloro-6-methylphenyl)-2-[[2-methyl-6-(1-piperazinyl-d8)-4-pyrimidinyl]amino]-5-thiazolecarboxamide; Dasatinib Metabolite M4-d8. Grade: ≥97% by HPLC; ≥98% atom D. CAS No. 1189998-96-6. Molecular formula: C20H14D8ClN7OS. Mole weight: 452.00. | |
| N-Desmethyl imatinib | N-Desmethyl imatinib. Group: Biochemicals. Alternative Names: N- [4-Methyl-3- [ [4- (3-pyridinyl) -2-pyrimidinyl] amino] phenyl] -4- (1-piperazinylmethyl) -benzamide; N-Desmethyl gleevec; CGP-74588. Grades: Highly Purified. CAS No. 404844-02-6. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C28H29N7O. US Biological Life Sciences. | Worldwide |
| N-Desmethyl Imatinib-[d4] | N-Desmethyl Imatinib-[d4] is the labelled analogue of N-Desmethyl Imatinib, which is a metabolite of Imatinib. Synonyms: Desmethyl imatinib D4; N-Desmethyl Imatinib-d4; N-[4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-4-(1-piperazinylmethyl)-benzamide-d4; N-Desmethyl Gleevec-d4; Norimatinib-d4; Imatinib EP Impurity C-d4. Grade: 95% by HPLC; 98% atom D. Molecular formula: C28H25D4N7O. Mole weight: 483.60. | |
| Palbociclib, Free Base Salt, 99+% | PD 0332991 is a potent selective inhibitor of cyclin dependent kinases CDK4 and CDK6 with in vitro IC50 = 11 nM (CDK4) and 16 nM (CDK6). PD 0332991 induces G1 arrest in retinoblastoma (Rb)-positive tumor cells. Group: Biochemicals. Alternative Names: 6-acetyl-8-cyclopentyl-5-methyl-2- [ [5- (1-piperazinyl) -2-pyridinyl]amino]pyrido [2, 3-d]pyrimidin-7 (8H) -one 2-hydroxy-ethanesulfonic acid (1:1); PD0332991; Palbociclib; isethionate. Grades: Highly Purified. CAS No. 571190-30-2. Pack Sizes: 25mg, 50mg, 100mg. US Biological Life Sciences. | Worldwide |
| PD 0332991 Isethionate (6-acetyl-8-cyclopentyl-5-methyl-2-[ [5- (1-piperazinyl) -2-pyridinyl]amino]pyrido [2, 3-d] pyrimidin-7(8H)-one isethionate salt) | Potent Cdk4/6 inhibitor (IC50 values are 11 and 15nm for Cdk4 and Cdk6 respectively). Selective for Cdk4/6 over a panel of 34 additional protein kinases (IC50 values are > 10um). Induces G1 cell cycle arrest and senescence in retinoblastoma protein (Rb)-proficient cell lines; blocks growth of intracranial glioblastoma multiforme xenografts in mice. Brain penetrant. Group: Biochemicals. Grades: Highly Purified. CAS No. 827022-33-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Our database is helping our users find suppliers everyday.
