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5'-DMT-NHS-Carboxy dU 3'-Phosphoramidite is a phosphoramidite compound used in the synthesis of oligonucleotides. It is designed to incorporate a modified deoxyuridine nucleotide into DNA strands, which can enhance the stability and functionality of the synthesized oligonucleotides. This compound is used to improve the metabolic stability and binding affinity of the synthesized oligonucleotides, making them more suitable for specific biological applications such as gene regulation, and antisense therapy. Synonyms: N-Hydroxysuccinimide carboxy-dT phosphoramidite; 2-Propenoic acid, 3-[1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinyl]-, 2,5-dioxo-1-pyrrolidinyl ester; 2,5-Dioxo-1-pyrrolidinyl 3-[1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinyl]-2-propenoate; NHS-Carboxy-dT; 5'-Dimethoxytrityl-5-[3-acrylate NHS ester]-2'-deoxyUridine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 5'-DMT-5-NHS-carboxy-2'-deoxy-rU 3'-Phosphoramidite. CAS No. 1354695-41-2. Molecular formula: C46H52N5O12P. Mole weight: 897.91.
6-Fluorescein dT phosphoramidite
6-Fluorescein dT phosphoramidite can be inserted into the desired sequence as a replacement for a dT residue during oligonucleotides synthesis. Synonyms: Uridine, 5-[3-[[6-[[[3',6'-bis(2,2-dimethyl-1-oxopropoxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-6-yl]carbonyl]amino]hexyl]amino]-3-oxo-1-propen-1-yl]-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5'-Dimethoxytrityloxy-5-[N-((3',6'-dipivaloylfluoresceinyl)-aminohexyl)-3-acrylimido]-2'-deoxyuridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Fluorescein-dT Phosphoramidite; Fluorescein dT CEP; 6-FAM-dT Phosphoramidite. Grade: ≥95%. CAS No. 1194507-30-6. Molecular formula: C79H89N6O17P. Mole weight: 1425.56.
Amino-Modifier C6 dC
Amino-Modifier C6 dC is designed for automatic synthesis. During oligonucleotide synthesis, the addition of the amino modifier dC can replace the dC residue to functionalize the target oligonucleotide. Synonyms: Amino-modifier-C6-dC Phosphoramidite; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxy-N-[(dimethylamino)methylene]-5-[(1E)-3-oxo-3-({6-[(trifluoroacetyl)amino]hexyl}amino)-1-propen-1-yl]cytidine; 5'-Dimethoxytrityl-N-dimethylformamidine-5-[N-(trifluoroacetylaminohexyl)-3-acrylimido]-2'-deoxycytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Amino-Modifier C6 dC CEP; Amino-modifier-C6-dC-CE-Phosphoramidite; Cytidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-[(dimethylamino)methylene]-5-[3-oxo-3-[[6-[(trifluoroacetyl)amino]hexyl]amino]-1-propenyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]. Grade: ≥95%. CAS No. 853955-92-7. Molecular formula: C53H68F3N8O9P. Mole weight: 1049.12.
BBQ-650-DT CEP
BBQ-650-DT CEP is a revolutionary chemical amalgamation employed with an aim to precisely target cancerous cells. Its exceptionally selective inhibition explicitly curtails the activity of an intricate protein implicated in the pernicious development of tumors. Synonyms: 5'-Dimethoxytrityloxy-5-[6-(9-[4-nitro-2',5'-dimethoxyazobenz-4'-yldiazo]-julolidin-8-oxy)-hexylamidoethyl-3-acrylimido]-2'-deoxyUridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Grade: 95%. CAS No. 905554-46-3. Molecular formula: C76H89N12O15P. Mole weight: 1441.57.
BHQ-1-dT CE Phosphoramidite
BHQ-1-dT, a widely utilized reagent in the biomedicine realm, remains pertinent for nucleic acid detection and DNA sequencing. Its potential significance surfaces in disease and genetic disorder determination alongside viral load monitoring in infectious cases. From a development standpoint, BHQ-1-dT fosters therapeutic targeting of nucleic acids. Synonyms: BHQ-1-dT; HCQ-12-dT Phosphoramidite; 5'-Dimethoxytrityloxy-5-[(N-4''-carboxyethyl-4''-(N-ethyl)-4'-(2-Nitro-4-toluyldiazo)-2'-methoxy-5'-methyl-azobenzene)-aminohexyl-3-acrylimido]-2'-deoxyUridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; BHQ-1-dT Amidite. Grade: ≥95%. Molecular formula: C74H89N12O14P. Mole weight: 1401.56.
BHQ-2-dT
BHQ-2-dT plays a critical role in propelling PCR probes and hybridization assays to new heights of detection, this modified nucleoside serves as a beacon for identifying viral pathogens, genetic diseases, and cancer biomarkers. With its distinctive fluorescent abilities, molecular matching is taken to the next level of precision and accuracy, boosting sensitivity like never before. Synonyms: HCQ-2-dT Phosphoramidite; BHQ-2-dT CE Phosphoramidite; 5'-Dimethoxytrityloxy-5-[(N-4''-carboxyethyl-4''-(N-ethyl)-4'-(4-Nitro-phenyldiazo)-2'-methoxy-5'-methoxy-azobenzene)-aminohexyl-3-acrylimido]-2'-deoxyUridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; BHQ-2-dT Phosphoramidite; BHQ-2-dT Amidite. Grade: ≥95%. CAS No. 1415097-34-5. Molecular formula: C73H87N12O15P. Mole weight: 1403.53.
Biotin-dT CE-Phosphoramidite
Biotin-dT CE-Phosphoramidite is a prestigious compound, engaged in the critical tasks of labeling and detecting DNA or RNA sequences. With the amalgamation of biotin, this meticulously modified nucleotide engenders a realm of convenience for meticulous purification processes, unrivaled amplification endeavors and captivating visualization techniques. Synonyms: 5'-Dimethoxytrityloxy-5-[N-((4-t-butylbenzoyl)-biotinyl)-aminohexyl)-3-acrylimido]-2'-deoxyUridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Biotin-dT Amidite; Biotin-dT Phosphoramidite; (2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(5-(3-((6-(5-((3aS,4S,6aR)-1-(4-(tert-butyl)benzoyl)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexyl)amino)-3-oxoprop-1-en-1-yl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-O-DMTr-5-[N-((4-t-butylbenzoyl)-biotinyl)-aminohexyl)-3-acrylimido]-2'-dT-3'-CE-phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-5-[N-((4-t-butylbenzoyl)-biotinyl)-aminohexyl)-3-acrylimido]-2'-deoxythymidine-3'-O-[(2-cyanoethyl)-N,N-diisopropyl]-phosphoramidite; Biotin-dT. Grade: 95%. CAS No. 198080-40-9. Molecular formula: C69H89N8O12PS. Mole weight: 1285.55.
Dabcyl-dT CEP
Dabcyl-dT CEP is an indispensable entity employed in the realm of biomedical investigation, serving as a pivotal constituent in the synthesis of altered nucleotide analogs. Synonyms: 5'-Dimethoxytrityloxy-5-[(N-4'-carboxy-4-(dimethylamino)-azobenzene)-aminohexyl-3-acrylimido]-2'-deoxyUridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Dabcyl-dT. CAS No. 316121-62-7. Molecular formula: C63H76N9O10P. Mole weight: 1150.32.
EDTA-C2-dT-CE Phosphoramidite
EDTA-C2-dT-CE Phosphoramidite, a catalyst for biomedical synthesis, is rich in EDTA, ensuring thorough metal ion chelation. Its enhanced stability and selectivity imply potential applications in disease research, including HIV and cancer. Employed mostly in genome editing, it exhibits profound biomedical value through its performance in the synthesis of trace oligonucleotides. Synonyms: 5'-Dimethoxytrityl-5-[N-ethylenediaminetriethylacetate,monoacetylaminoethyl-3-acrylimido]-2'-deoxyUridine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C60H81N8O16P. Mole weight: 1201.32.
Ferrocene-dT-CE Phosphoramidite
Ferrocene-dT-CE Phosphoramidite is a biomedicine tool used for the synthesis of oligonucleotides. Ferrocene-dT, a derivative of thymidine, acts as a redox-active reporter group while the CE phosphoramidite serves as a linker. This product plays an important role in the studies of DNA interactions, electrochemical properties and hybridization of DNA oligomers. Synonyms: 5'-dimethoxytrityloxy-5-[N-acetyl ferrocenyl-aminohexyl)-3-acrylimido]-2'-deoxyUridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C60H73FeN6O10P. Mole weight: 1125.07.
Fmoc Amino-Modifier C6 dT
Fmoc Amino-Modifier C6 dT is renowned for its versatility, facilitating the synthesis of a wide range of compounds. It finds prominent utility in the modification of oligonucleotides for multifaceted applications such as drug delivery, gene therapy and the investigation of nucleic acid interactions. Synonyms: 5'-Dimethoxytrityl-5-[N-((9-fluorenylmethoxycarbonyl)-aminohexyl)-3-acrylimido]-2'-deoxyUridine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C63H73N6O11P. Mole weight: 1121.28.
m-Xylylenediamine/acrylonitrile adduct
m-Xylylenediamine/acrylonitrile adduct. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,3(or4)-Benzenedimethanamine,acrylonitrilereactionproducts;Benzenedimethanamine,N-(2-cyanoethyl)derivs.;M-XYLYLENEDIAMINE/ACRYLONITRILE ADDUCT. Product Category: Polymer/Macromolecule. CAS No. 73050-11-0. Molecular formula: C11H15N3. Mole weight: 189.26. Product ID: ACM73050110. Alfa Chemistry ISO 9001:2015 Certified.
N-(2-Cyanoethyl)-L-valine
A metabolite of Acrylonitrile. Group: Biochemicals. Alternative Names: N-(2-Cyanoethyl)valine. Grades: Highly Purified. CAS No. 51078-49-0. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
N-(2-Cyanoethyl)-L-Valine-[d3]
N-(2-Cyanoethyl)-L-Valine-[d3]. Uses: A labelled metabolite of acrylonitrile. Synonyms: N-(2-Cyanoethyl-d3)-L-valine. CAS No. 160210-22-0. Molecular formula: C8H11D3N2O2. Mole weight: 173.22.
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