Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| 3'-GMP | 3'-GMP is a metabolite of guanosine-2',3'-cyclic monophosphate. Synonyms: Guanosine- 3'- O- monophosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 6027-83-4. Molecular formula: C10H14N5O8P (free acid). Mole weight: 363.2 (free acid). |  |
| 2'-/3'-AEC-5'-GMP | 2'-/3'-AEC-5'-GMP is an analogue of guanosine-5'-O-monophosphate used as a ligand for immobilization and coupling of diffferent dyes and labels. Synonyms: 2'- / 3'- O- (2- Aminoethylcarbamoyl)guanosine- 5'- O- monophosphate, sodium salt. Grade: ≥ 97 % by HPLC. Molecular formula: C13H20N7O9P (free acid). Mole weight: 449.3 (free acid). | |
| 2'-/3'-AHC-5'-GMP | 2'-/3'-AHC-5'-GMP is an analogue of guanosine-5'-O-monophosphate used as a ligand for immobilization and for coupling of different dyes and labels. Synonyms: 2'- / 3'- O- (6- Aminohexylcarbamoyl)guanosine- 5'- O- monophosphate, sodium salt. Grade: ≥ 97 % by HPLC. Molecular formula: C17H28N7O9P (free acid). Mole weight: 505.4 (free acid). | |
| 2'-/3'-TAMRA-AEC-5'-GMP | 2'-/3'-TAMRA-AEC-5'-GMP is a fluorescent analogue of guanosine-5'-monophosphate (λexc555 nm; λem580 nm). Synonyms: 2'- / 3'- O- (6- [Tetramethylrhodaminyl]aminoethylcarbamoyl)guanosine- 5'- O- monophosphate, sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C38H40N9O13P (free acid). Mole weight: 861.8 (free acid). | |
| 3',5'-cyclic-GMP phosphodiesterase | This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. Group: Enzymes. Synonyms: guanosine cyclic 3',5'-phosphate phosphodiesterase; cyclic GMP phosphodiesterase; cyclic 3',5'-GMP phosphodiesterase; cyclic guanosine 3',5'-monophosphate phosphodiesterase; cyclic guanosine 3',5'-phosphate phosphodiesterase; cGMP phosphodiesterase; cGMP-PDE. Enzyme Commission Number: EC 3.1.4.35. CAS No. 9068-52-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3719; 3',5'-cyclic-GMP phosphodiesterase; EC 3.1.4.35; 9068-52-4; guanosine cyclic 3',5'-phosphate phosphodiesterase; cyclic GMP phosphodiesterase; cyclic 3',5'-GMP phosphodiesterase; cyclic guanosine 3',5'-monophosphate phosphodiesterase; cyclic guanosine 3',5'-phosphate phosphodiesterase; cGMP phosphodiesterase; cGMP-PDE. Cat No: EXWM-3719. |  |
| 8-[(6-Amino)hexyl]-amino-GMP - ATTO-390 | 8-[(6-Amino)hexyl]-amino-GMP - ATTO-390 is a powerful and versatile fluorescent probe that shines a light on the molecular biology field. This scientific breakthrough is a crucial tool for biomedical research as it enables sensitive detection and visualization of RNA in cells and tissues. Not just limited to research, it also has diagnostic capabilities for varied diseases like cancer and viral infections. With its unique fluorescent properties, it opens new doors for clinical diagnostics of RNA in molecular biology. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO 390, Triethylammonium salt. Grade: ≥ 95% by HPLC. Molecular formula: C36H51N8O11P (free acid). Mole weight: 802.82 (free acid). | |
| 2'-Deoxyguanosine-5'-monophosphate | 2'-Deoxyguanosine-5'-monophosphate, a nucleotide molecule and a key player in DNA synthesis, holds immense potential in the development of antiviral drugs as well as in treating various cancers. This biochemical marker is additionally crucial in detecting and measuring DNA damage, a necessary step in studying the complex mechanisms of DNA replication and repair. Synonyms: 2'-Deoxyguanylic acid; dGMP; Deoxyguanylic acid; Deoxy-GMP; 2'-Deoxyguanosine 5'-phosphate; Deoxyguanosine 5'-monophosphate; 2'-Deoxy-GMP; 2'-Deoxy-5'-guanylic acid; Guanosine, 2'-deoxy-, 5'-(dihydrogen phosphate); 2'-Desoxyguanosine 5'-(dihydrogen phosphate); 9-(2-Deoxy-5-O-phosphono-β-D-erythro-pentofuranosyl)-2-imino-3,9-dihydro-2H-purin-6-ol. Grade: ≥98% by HPLC. CAS No. 902-04-5. Molecular formula: C10H14N5O7P. Mole weight: 347.22. | |
| 2'-GMP | 2'-GMP is a metabolite of guanosine-2',3'-cyclic monophosphate. Synonyms: Guanosine- 2'- O- monophosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 130-50-7. Molecular formula: C10H14N5O8P (free acid). Mole weight: 363.2 (free acid). | |
| 2-NH2-6-Cl-5'-PuMP | 2-NH2-6-Cl-5'-PuMP is an analogue of guanosine-5'-O-monophosphate and an inhibitor of IMP dehydrogenase. It is often used as the precursor for 6-modified 5'-GMP derivatives. Synonyms: 2-Amino-6-chloropurine riboside-5'-O-monophosphate, sodium salt. Grade: ≥ 97% by HPLC. CAS No. 16321-98-5. Molecular formula: C10H13ClN5O7P (free acid). Mole weight: 381.67. | |
| 2'-O-Methylguanosine 5'-monophosphate | 2'-O-Methylguanosine 5'-monophosphate triethylammonium salt is a critical compound extensively used in the biomedical industry. It plays a crucial role in the treatment and research of various diseases, including viral infections, cancer, and neurological disorders. This product contributes to the development of targeted therapies and is an essential component in nucleic acid-based drug formulations. Its high purity and quality make it a valuable tool for biomedical research and drug discovery. Synonyms: 2'-O-Methyl-5'-guanylic acid; 2'-O-Mgmp; 2'-O-Methyl-guanosine 5'-monophosphate; 2'-O-Me-GMP; 2'-O-Methylguanosine 5'-(dihydrogen phosphate). Grade: ≥95% by HPLC. CAS No. 24121-01-5. Molecular formula: C11H16N5O8P. Mole weight: 377.25. | |
| 3',3'-cGAMP | c-(ApGp) is an analogue of c-diAMP and c-diGMP, the bacterial second messengers, which plays a role in Vibrio choleraepathogenesis and activates the production of interferon via STING. Synonyms: 3'-Guanylic acid, adenylyl-(3'→5')-, cyclic nucleotide; 2',3'-CGAMP; 3',3'-Cyclic guanosine adenosine monophosphate; cGAMP; Cyclic [G(3',5')pA(3',5')p]; Cyclic AMP-GMP; Cyclic GMP-AMP; Cyclic (adenosine monophosphate-guanosine monophosphate); c-GpAp; 3',3'-cGAMP. Grade: ≥98%. CAS No. 849214-04-6. Molecular formula: C20H24N10O13P2. Mole weight: 674.41. | |
| 3',5'-cyclic-AMP phosphodiesterase | Requires Mg2+ or Mn2+ for activity. This enzyme is specific for 3',5'-cAMP and does not hydrolyse other nucleoside 3',5'-cyclic phosphates such as cGMP (cf. EC 3.1.4.17, 3,5-cyclic-nucleotide phosphodiesterase and EC 3.1.4.35, 3,5-cyclic-GMP phosphodiesterase). It is involved in modulation of the levels of cAMP, which is a mediator in the processes of cell transformation and proliferation. Group: Enzymes. Synonyms: cAMP-specific phosphodiesterase; cAMP-specific PDE; PDE1; PDE2A; PDE2B; PDE4; PDE7; PDE8; PDEB1; PDEB2. Enzyme Commission Number: EC 3.1.4.53. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3736; 3',5'-cyclic-AMP phosphodiesterase; EC 3.1.4.53; cAMP-specific phosphodiesterase; cAMP-specific PDE; PDE1; PDE2A; PDE2B; PDE4; PDE7; PDE8; PDEB1; PDEB2. Cat No: EXWM-3736. | |
| 3'-O-Methyl-5'-guanylic acid | 3-O-Methyl-5-guanylic acid is a pivotal molecule extensively employed in the realm of compound is assuming an eminent position in the research and development of sundry pharmaceutical agents and investigations concerning RNA and DNA architectures. Synonyms: 3'-OMe-GMP; 3'-O-Methylguanosine-5'-Monophosphate; 3'-O-Methylguanosine 5'-phosphate; 3'-O-Methylguanosine 5'-(dihydrogen phosphate); ((2R,3S,4R,5R)-5-(2-Amino-6-oxo-1H-purin-9(6H)-yl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)methyl dihydrogen phosphate. Grade: ≥98%. CAS No. 400806-41-9. Molecular formula: C11H16N5O8P. Mole weight: 377.25. | |
| 5'-Guanylic acid | 5'-Guanylic acid is a purine nucleotide that participates in physiological processes such as energy metabolism, signal transduction, and gene expression regulation. 5'-Guanylic acid regulates the expression of genes related to fatty acid metabolism. 5'-Guanylic acid is the weak agonist for ionotropic glutamate receptors (iGluR), reduces the activity of the glutamatergic system and exhibits neuroprotective effect. 5'-Guanylic acid also causes neuronal cell death at high concentrations[1][2][3]. Uses: Scientific research. Group: Natural products. Alternative Names: 5'-GMP; 5'-guanosine monophosphate. CAS No. 85-32-5. Pack Sizes: 50 mg; 100 mg. Product ID: HY-N5134. |  |
| 6-Methylthio-GMP | 6-Methylthio-GMP, a highly potent nucleotide analog, exhibits remarkable efficacy against diverse viral infections and several cancers. This promising molecule significantly interferes with DNA synthesis, thereby repressing tumor growth and inhibiting viral replication. Moreover, cutting-edge research indicates its potential for treating inflammation. Synonyms: 6-Methylthioguanosine-5'-monophosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C11H16N5O7PS (free acid). Mole weight: 393.31 (free acid). | |
| 6-Thio-GMP | 6-Thio-GMP, a bioactive compound employed for biomedical research, demonstrates inhibitory effects on numerous tumors, rendering it a prospective therapeutic intervention for leukemia and lymphoma. Moreover, it displays antiviral capability as validated by its potency to inhibit replication of viruses such as Ebola virus. Synonyms: 6-Thio-guanosine-5'-monophosphate, Sodium salt. Grade: ≥ 95% by HPLC. CAS No. 15867-02-4. Molecular formula: C10H14N5O7PS (free acid). Mole weight: 379.28 (free acid). | |
| 7-methylguanosine nucleotidase | The enzyme also has low activity with N7-methyl-GDP, producing N7-methyl-GMP. Does not accept AMP or GMP, and has low activity with UMP. Group: Enzymes. Synonyms: cytosolic nucleotidase III-like; cNIII-like; N7-methylguanylate 5'-phosphatase. Enzyme Commission Number: EC 3.1.3.91. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3698; 7-methylguanosine nucleotidase; EC 3.1.3.91; cytosolic nucleotidase III-like; cNIII-like; N7-methylguanylate 5'-phosphatase. Cat No: EXWM-3698. | |
| 8-Bromoguanosine-5'-O-monophosphate(8-br-5'-gmp) | 8-Bromoguanosine-5'-O-monophosphate(8-br-5'-gmp). Uses: Designed for use in research and industrial production. Additional or Alternative Names: SureCN2775572, 5-Guanylic acid, 8-bromo-, CTK0J7067, AG-E-59693, 21870-09-7. Product Category: Heterocyclic Organic Compound. CAS No. 21870-09-7. Molecular formula: C10H13BrN5O8P. Mole weight: 442.1. Purity: 0.96. IUPACName: [(2R,3S,4R,5R)-5-(2-amino-8-bromo-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate. Product ID: ACM21870097. Alfa Chemistry ISO 9001:2015 Certified. |  |
| adenosylcobinamide-phosphate guanylyltransferase | In Salmonella typhimurium LT2, under anaerobic conditions, CobU (EC 2.7.7.62 and EC 2.7.1.156), CobT (EC 2.4.2.21), CobC (EC 3.1.3.73) and CobS (EC 2.7.8.26) catalyse reactions in the nucleotide loop assembly pathway, which convert adenosylcobinamide (AdoCbi) into adenosylcobalamin (AdoCbl). CobT and CobC are involved in 5,6-dimethylbenzimidazole activation whereby 5,6-dimethylbenzimidazole is converted to its riboside, α-ribazole. The second branch of the nuclotide loop assembly pathway is the cobinamide (Cbi) activation branch where AdoCbi or adenosylcobinamide-phosphate is converted to the activated intermediate AdoCbi-GDP by the bifunctional enzyme Cob U. Th.s a two-stage reaction with formation of a CobU-GMP intermediate. Guanylylation takes place at histidine-46. Group: Enzymes. Synonyms: CobU; adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; AdoCbi kinase/AdoCbi-phosphate guanylyltransferase. Enzyme Commission Number: EC 2.7.7.62. CAS No. 169592-55-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3274; adenosylcobinamide-phosphate guanylyltransferase; EC 2.7.7.62; 169592-55-6; CobU; adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; AdoCbi kinase/AdoCbi-phosphate guanylyltransferas. | |
| c-Di-GMP | c-diGMP is a bacterial second messenger and a STING ligand. Synonyms: 3'-Guanylic acid, guanylyl-(3'→5')-, cyclic nucleotide; 5GP-5GP; Cyclic di-3',5'-guanylate; Cyclic diguanylate; Cyclic diguanylate monophosphate; Cyclic-di-GMP; cGpGp; Cyclic diguanylic acid; cdiGMP; 3',5'-Cyclic diguanylic acid; c-(Gpgp); Bis(3',5')-cyclic diguanylic acid. Grade: ≥95%. CAS No. 61093-23-0. Molecular formula: C20H24N10O14P2. Mole weight: 690.41. | |
| cGAMP disodium | cGAMP diammonium activates stimulator of interferon genes (STING). cGAMP (Cyclic GMP-AMPP) disodium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. Synonyms: 3',3'-cGAMP disodium salt; 3'-Guanylic acid, adenylyl-(3'→5')-, cyclic nucleotide, disodium salt; 2',3'-CGAMP disodium salt; 3',3'-Cyclic guanosine adenosine monophosphate disodium salt; Cyclic [G(3',5')pA(3',5')p] disodium salt; Cyclic AMP-GMP disodium salt; Cyclic GMP-AMP disodium salt; Cyclic (adenosine monophosphate-guanosine monophosphate) disodium salt. Grade: 98%. CAS No. 2407516-83-8. Molecular formula: C20H22N10Na2O13P2. Mole weight: 718.37. | |
| Cyclic-di-GMP disodium | Cyclic-di-GMP disodium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP disodium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP disodium can be used in cancer research[1][2][3][4]. Uses: Scientific research. Group: Natural products. Alternative Names: c-di-GMP disodium; cyclic diguanylate disodium; 5GP-5GP disodium. CAS No. 2222132-40-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-110382. | |
| Cyclic di-GMP disodium salt | Cyclic di-GMP is a second messenger in bacteria, which is involved in diverse prokaryotic processes, including biofilm formation, motility, virulence, and cell cycling. Cyclic di-GMP induces expression of IFN-β mRNA in vitro (EC50 = 537.8 nM) but less potently than 2'3'-cGAMP, 3'2'-cGAMP, 3'3'-cGAMP, and 2'2'-cGAMP. Synonyms: Cyclic-di-GMP.Na2; 3'-Guanylic acid, guanylyl-(3'→5')-, cyclic nucleotide, disodium salt; 5GP-5GP disodium salt; Cyclic di-3',5'-guanylate disodium salt; Cyclic diguanylate disodium salt; Cyclic diguanylate monophosphate disodium salt; Cyclic-di-GMP disodium salt; cGpGp disodium salt; Cyclic diguanylic acid disodium salt; cdiGMP disodium salt; 3',5'-Cyclic diguanylic acid; disodium salt c-(Gpgp) disodium salt; Bis(3',5')-cyclic diguanylic acid disodium salt; Cyclic di-GMP sodium salt; c-di-GMP disodium salt. Grade: ≥95%. CAS No. 2222132-40-1. Molecular formula: C20H22N10Na2O14P2. Mole weight: 734.37. | |
| Cyclic diguanosine monophosphate | Cyclic diguanosine monophosphate. Group: Biochemicals. Alternative Names: C-di-GMP; Cyclic-di-GMP; Cyclic bis (3',5') diguanylic acid; Cyclic diguanylate. Grades: Highly Purified. CAS No. 61093-23-0. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C20H24N10O14P2. US Biological Life Sciences. |  Worldwide |
| Cyclic GMP | Cyclic GMP (cGAMP) is an endogenous second messenger that triggers interferon production in response to cytoplasmic DNA. Cyclic GMP can activate the stimulator of interferon genes (STING), activating the signaling cascade that leads to the production of type I interferons and other immune mediators. Cyclic-GMP-AMP, a conjugate of cyclic GMP and AMP, can induce IRF3 phosphorylation and nuclear translocation, enhancing antiviral immune responses. cGMP may also activate PDE to degrade cAMP, inhibit myocardial calcium current I Ca , and regulate myocardial contractility. The derivative of cyclic GMP (cGMP), 8-Br-cGMP, has antiplatelet activity, and cyclic GMP can be used in the study of antiviral immunity and cardiovascular diseases [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 7665-99-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-113469. | |
| Cyclic GMP sodium | Cyclic GMP (cGAMP) sodium is an endogenous second messenger that triggers interferon production in response to cytoplasmic DNA. Cyclic GMP sodium can activate the stimulator of interferon genes (STING), activating the signaling cascade that leads to the production of type I interferons and other immune mediators. Cyclic-GMP-AMP, a conjugate of cyclic GMP and AMP, can induce IRF3 phosphorylation and nuclear translocation, enhancing antiviral immune responses. Cyclic GMP sodium may also activate PDE to degrade cAMP, inhibit myocardial calcium current I Ca , and regulate myocardial contractility. The derivative of Cyclic GMP sodium, 8-Br-cGMP, has antiplatelet activity, and Cyclic GMP sodium can be used in the study of antiviral immunity and cardiovascular diseases [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 40732-48-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-113469A. | |
| Cyclic GMP sodium salt | Cyclic GMP or cGMP is a second messenger and it is biosynthesized from GTP by guanylate cyclases. Nitric oxide and natriuretic peptides arw activators of guanylate cyclases. cGMP activates protein kinase G (PKG) and modulates ion channel conductance, with signaling affecting diverse processes including smooth muscle relaxation and proliferation, phototransduction, and energy homeostasis. Synonyms: cGMP sodium salt; Cyclic guanosine monophosphate sodium salt; Guanosine 3'5'-cyclic monophosphate sodium salt; Monosodium-GMP; Guanosine, cyclic 3',5'-(hydrogen phosphate), sodium salt (1:1); Guanosine, cyclic 3',5'-(hydrogen phosphate), monosodium salt; Cyclic 3',5'-guanosine monophosphate monosodium salt; Guanosine monophosphate monosodium salt; 3',5'-Cyclic GMP monosodium salt. Grade: 98%. CAS No. 40732-48-7. Molecular formula: C10H11N5NaO7P. Mole weight: 367.19. | |
| cyclic-guanylate-specific phosphodiesterase | Requires Mg2+ or Mn2+ for activity and is inhibited by Ca2+ and Zn2+. Contains a heme unit. This enzyme linearizes cyclic di-3,5-guanylate, the product of EC 2.7.7.65, diguanylate cyclase and an allosteric activator of EC 2.4.1.12, cellulose synthase (UDP-forming), rendering it inactive. It is the balance between these two enzymes that determines the cellular level of c-di-GMP. Group: Enzymes. Synonyms: cyclic bis(3?5')diguanylate phosphodiesterase; c-di-GMP-specific phosphodiesterase; c-di-GMP phosphodiesterase; phosphodiesterase (misleading); phosphodiesterase A1; PDEA1; VieA. Enzyme Commission Number: EC 3.1.4.52. CAS No. 338732-46-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3735; cyclic-guanylate-specific phosphodiesterase; EC 3.1.4.52; 338732-46-0; cyclic bis(3?5')diguanylate phosphodiesterase; c-di-GMP-specific phosphodiesterase; c-di-GMP phosphodiesterase; phosphodiesterase (misleading); phosphodiesterase A1; PDEA1; VieA. Cat No: EXWM-3735. | |
| D(+)-Raffinose pentahydrate | D(+)-Raffinose pentahydrate is an orally active inhibitor of LecA ( K d = 32 μM) and GtfC. D(+)-Raffinose pentahydrate reduces cyclic diguanylate (c-di-GMP) by increased activity of a c-di-GMP specific phosphodiesterase. D(+)-Raffinose pentahydrate interferes with GTF function. D(+)-Raffinose pentahydrate decreases IL-4 and IL-5 mRNA. D(+)-Raffinose pentahydrate exhibits biofilm-inhibitory activity against Pseudomonas aeruginosa and Streptococcus mutans and inhibits allergic airway eosinophilia [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: D-Raffinose pentahydrate. CAS No. 17629-30-0. Pack Sizes: 10 mM * 1 mL; 5 g. Product ID: HY-N1938. | |
| GDP-Mannose pyrophosphorylase from Pyrococcus furiosus, Recombinant | In enzymology, a mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) is an enzyme that catalyzes the chemical reaction: GTP + alpha-D-mannose 1-phosphate ? diphosphate + GDP-mannose. Thus, the two substrates of this enzyme are GTP and alpha-D-mannose 1-phosphate, whereas its two products are diphosphate and GDP-mannose. Group: Enzymes. Synonyms: GTP-mannose-1-phosphate guanylyltransferase; PIM-GMP; GDP-mannose pyrophosphorylase; guanosine 5'-diphospho-D-mannose pyrophosphorylase; guanosine diphosphomannose pyrophosphorylase; guanosine triphosphate-mannose 1-phosphate guanylyltransferase; mannose 1-phosphate guanylyltransferase (guanosine triphosphate); mannose-1-phosphate guanylyltransferase; EC 2.7.7.13. Enzyme Commission Number: EC 2.7.7.13. CAS No. 37278-24-3. Purity: min 95% by SDS-PAGE. GDP-Mannose pyrophosphorylase. Source: E. coli. Species: Pyrococcus furiosus. GTP-mannose-1-phosphate guanylyltransferase; PIM-GMP; GDP-mannose pyrophosphorylase; guanosine 5'-diphospho-D-mannose pyrophosphorylase; guanosine diphosphomannose pyrophosphorylase; guanosine triphosphate-mannose 1-phosphate guanylyltransferase; mannose 1-phosphate guanylyltransferase (guanosine triphosphate); mannose-1-phosphate guanylyltransferase; EC 2.7.7.13. Cat No: NATE-1504. | |
| Guanosine 5'-monophosphate | Guanosine 5'-monophosphate is a purine ribonucleoside 5'-monophosphate having guanine as the nucleobase. It has a role as a metabolite, a biomarker, an Escherichia coli metabolite and a mouse metabolite. It is a guanosine 5'-phosphate and a purine ribonucleoside 5'-monophosphate. It is a conjugate acid of a guanosine 5'-monophosphate(2-). Guanosine 5 '-monophosphate is a guanine nucleotide containing one phosphate group, which is esterified into the sugar moiety and widely found in nature. Synonyms: 5-Guanylic Acid; 5'-GMP; GMP; Guanidine Monophosphate; Guanosine 5'-Phosphate; Guanosine 5'-Phosphoric Acid; Guanosine Monophosphate; Guanylic Acid. Grade: ≥95%. CAS No. 85-32-5. Molecular formula: C10H14N5O8P. Mole weight: 363.22. | |
| Guanosine-5'-O-monophosphorothioate | Guanosine-5'-O-monophosphorothioate is a critical biomolecular compound with broad utilization for studying viral infections, cancer and neurodegenerative ailments. Synonyms: GMPS; 5'-O-thiophosphonoguanosine; 5'-GMPS. CAS No. 76310-16-2. Molecular formula: C10H14N5O7PS. Mole weight: 379.29. | |
| mannose-1-phosphate guanylyltransferase | The bacterial enzyme can also use ITP and dGTP as donors. Group: Enzymes. Synonyms: GTP-mannose-1-phosphate guanylyltransferase; PIM-GMP (phosphomannose isomerase-guanosine 5'-diphospho-D-mannose pyrophosphorylase); GDP-mannose pyrophosphorylase; guanosine 5'-diphospho-D-mannose pyrophosphorylase; guanosine diphosphomannose pyrophosphorylase; guanosine triphosphate-mannose 1-phosphate guanylyltransferase; mannose 1-phosphate guanylyltransferase (guanosine triphosphate). Enzyme Commission Number: EC 2.7.7.13. CAS No. 37278-24-3. GDP-Mannose pyrophosphorylase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3229; mannose-1-phosphate guanylyltransferase; EC 2.7.7.13; 37278-24-3; GTP-mannose-1-phosphate guanylyltransferase; PIM-GMP (phosphomannose isomerase-guanosine 5'-diphospho-D-mannose pyrophosphorylase); GDP-mannose pyrophosphorylase; guanosine 5'-diphospho-D-mannose pyrophosphorylase; guanosine diphosphomannose pyrophosphorylase; guanosine triphosphate-mannose 1-phosphate guanylyltransferase; mannose 1-phosphate guanylyltransferase (guanosine triphosphate). Cat No: EXWM-3229. | |
| Native Aspergillus oryzae Ribonuclease T1 | Ribonuclease T1 (RNase T1) from Aspergillus oryzae is an endoribonuclease that hydrolyzes after G residues. Cleavage occurs between the 3-phosphate group of a guanidine ribonucleotide and 5-hydroxyl of the adjacent nucleotide. The initial product is a 2:3 cyclic phosphate nucleoside that is hydrolyzed to the corresponding 3-nucleoside phosphate. It differs from Pancreatic RNase in that it attacks the guanine sites specifically to yield 3'-GMP and oligonucleotides with a 3'-GMP terminal group. Applications: Ribonuclease t1 (rnase t1) from aspergillus oryzae is used to digest denatured rna prior to sequencing and is used for protein folding studies. Group: Enzymes. Synonyms: Ribonuclease T1; EC 3.1.27.3; g. Enzyme Commission Number: EC 3.1.27.3. CAS No. 9026-12-4. Rnase. Activity: 300,000-600,000 units/mg protein. Storage: -20°C. Form: ammonium sulfate suspension; Suspension in 2.8 M (NH4)2SO4 solution. Source: Aspergillus oryzae. Ribonuclease T1; EC 3.1.27.3; guanyloribonuclease; Aspergillus oryzae ribonuclease; RNase N1; RNase N2; ribonuclease N3; ribonuclease U1; ribonuclease F1; ribonuclease Ch; ribonuclease PP1; ribonuclease SA; RNase F1; ribonuclease C2; binase; RNase Sa; guanyl-specific RNase; RNase G; RNase T1; ribonuclease guaninenucleotido-2'-transferase (cyclizing); ribonuclease N3; ribonuclease N1; 9026-12-4. Cat No: NATE-0658. | |
| Phosphodiesterase 5A1 from Human, Recombinant | PDE5 regulates vascular smooth muscle contraction and is involved in NO-cGMP signaling in platelets to control aggregation. PDE5 may also be involved in the regulation of cGMP signaling in the brain and may modulate pressure-induced cardiac hypertrophy and fibrosis. N-terminal gst-tagged 126 kda full-length protein. Applications: Phosphodiesterase (pde) is an enzyme that is used to breaks phosphodiester bonds. pde5 is a molecular target for the treatment of erectile dysfunction and pulmonary hypertension. pde5 is used to find novel pde5 inhibitors. Group: Enzymes. Synonyms: CN5N; phosphodiesterase 5A, cGMP-specific; PDE5A1; PDE5A; 3',5'-cyclic-GMP phosphodiesterase, PDE 5A1. Phosphodiesterase. Mole weight: 126 kDa. Storage: -70°C. Form: Supplied as a solution in 20% glycerol containing 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% TWEEN 20 and 3 mM DTT. Source: Sf9 cells. Species: Human. CN5N; phosphodiesterase 5A, cGMP-specific; PDE5A1; PDE5A; 3',5'-cyclic-GMP phosphodiesterase, PDE 5A1. Cat No: NATE-0527. | |
| Zaprinast (1,4-Dihydro-5-[2-propoxyphenyl]-7H-1,2,3-triazolo[4,5-d]pyrimidine-7-one) | A selective inhibitor of cyclic-GMP phosphodiesterase (PDE V, calmodulin insensitive). Since cGMP mediates the vasorelaxant action of nitric oxide, as well as the natriuretic and diuretic effect of a. Group: Biochemicals. Alternative Names: 1,4-Dihydro-5-[2-propoxyphenyl]-7H-1,2,3-triazolo[4,5-d]pyrimidine-7-one. Grades: Highly Purified. CAS No. 37762-06-4. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 2'2'-cGAMP | c[A(2',5')pG(2',5')p] is a cyclic dinucleotide analogue of c[G(2',5')pA(3',5')p], the metazoan second messenger and STING activator. It can bind the signalling protein STING and induces type I interferons. Synonyms: cGAMP(2'-5'); 2'-Guanylic acid, adenylyl-(2'→5')-, cyclic nucleotide; c[G(2',5')pA(2',5')p]; 2',5'-cyclic GMP-AMP; Cyclic (adenosine-(2'→5')-monophosphate-guanosine-(2'→5')-monophosphate). Grade: ≥98% by HPLC. CAS No. 1465774-27-9. Molecular formula: C20H24N10O13P2. Mole weight: 674.41. | |
| 2',3'-cGAMP | 2',3'-cGAMP (2'-3'-cyclic GMP-AMP) is a endogenous cGAMP in mammalian cells. 2',3'-cGAMP binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2',3'-cGAMP is produced in mammalian cells in response to DNA in the cytoplasm [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 2'-3'-cyclic GMP-AMP. CAS No. 1441190-66-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100564. | |
| 2',3'-cGAMP | 2',3'-cGAMP was considered to be the metazoan second messenger which is produced by cGAMP synthase (cGAS), the mammalian intrinsic immune DNA sensor. It can activate innate immunity by directly binding the endoplasmic reticulum-resident receptor STING (stimulator of interferon genes). Synonyms: Cyclic [G(2',5')pA(3',5')p]; 2'-Guanylic acid, adenylyl-(3'→5')-, cyclic nucleotide; 2',3'-Cyclic guanosine adenosine monophosphate; 2',3'-Cyclic guanosine monophosphate-adenosine monophosphate; 2'-3'-cyclic GMP-AMP; cGAMP(2'→5'); c[G(2',5')pA(3',5')p]; Cyclic Gp(2'→5')Ap(3'→5'). Grade: ≥95%. CAS No. 1441190-66-4. Molecular formula: C20H24N10O13P2. Mole weight: 674.41. | |
| 2',3'-cGAMP sodium | 2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium) is a endogenous cGAMP in mammalian cells. 2',3'-cGAMP sodium binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2',3'-cGAMP sodium is produced in mammalian cells in response to DNA in the cytoplasm [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 2'-3'-cyclic GMP-AMP sodium. CAS No. 2734858-36-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-100564A. | |
| 2',3'-cGAMP sodium salt | 2',3'-cGAMP sodium is an endogenous cGAMP in mammalian cells. 2',3'-cGAMP sodium binds to STING with a high affinity and is a potent inducer of interferon-β. 2',3'-cGAMP is an effective adjuvant that boosts the production of antigen-specific antibodies and T cell responses in mice. Synonyms: Cyclic [G(2',5')pA(3',5')p] sodium; cyclic GMP-AMP sodium; 2',3'-cyclic GMP-AMP sodium; 2',3'-Cyclic guanosine monophosphate-adenosine monophosphate sodium salt. Grade: 95%. CAS No. 2734858-36-5. Molecular formula: C20H22N10Na2O13P2. Mole weight: 718.38. | |
| 2'-O-Succinylguanosine 3',5'-cyclic monophosphate sodium salt | 2'-O-Succinylguanosine 3',5'-cyclic monophosphate sodium salt is a groundbreaking biomedical compound, acting as an agonist for distinct receptor to initiate intricate cellular signaling cascades that effectively impede tumor cell proliferation. Synonyms: Guanosine, cyclic 3',5'-(hydrogen phosphate) 2'-(hydrogen butanedioate), monosodium salt; 2'-O-Succinyl-3',5'-cyclic GMP monosodium salt; 2'-O-Succinylguanosine 3',5'-monophosphate monosodium salt. Grade: 95%. CAS No. 104809-11-2. Molecular formula: C14H16N5NaO10P. Mole weight: 468.27. | |
| 3',5'-cyclic-nucleotide phosphodiesterase | Acts on 3',5'-cyclic AMP, 3',5'-cyclic dAMP, 3',5'-cyclic IMP, 3',5'-cyclic GMP and 3',5'-cyclic CMP. Group: Enzymes. Synonyms: cyclic 3',5'-mononucleotide phosphodiesterase; PDE; cyclic 3',5'-nucleotide phosphodiesterase; cyclic 3',5'-phosphodiesterase; 3',5'-nucleotide phosphodiesterase; 3':5'-cyclic nucleotide 5'-nucleotidohydrolase; 3',5'-cyclonucleotide phosphodiesterase; cyclic nucleotide phosphodiesterase; 3', 5'-cyclic nucleoside monophosphate p. Enzyme Commission Number: EC 3.1.4.17. CAS No. 9040-59-9. PDE. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3716; 3',5'-cyclic-nucleotide phosphodiesterase; EC 3.1.4.17; 9040-59-9; cyclic 3',5'-mononucleotide phosphodiesterase; PDE; cyclic 3',5'-nucleotide phosphodiesterase; cyclic 3',5'-phosphodiesterase; 3',5'-nucleotide phosphodiesterase; 3':5'-cyclic nucleotide 5'-nucleotidohydrolase; 3',5'-cyclonucleotide phosphodiesterase; cyclic nucleotide phosphodiesterase; 3', 5'-cyclic nucleoside monophosphate phosphodiesterase; 3': 5'-monophosphate phosphodiesterase (cyclic CMP); cytidine 3':5'-monophosphate phosphodiesterase (cyclic CMP); cyclic 3',5-nucleotide monophosphate phosphodiesterase; nucleoside 3',5'-cyclic phosphate diesterase; nucleoside-3',5-monophosphate phosphodiesterase. Cat No: EXWM-3716. | |
| 3-Methylxanthine | 3-Methylxanthine, a xanthine derivative, is a cyclic guanosine monophosphate (GMP) inhibitor, with an IC 50 of 920 μM on guinea-pig isolated trachealis muscle. Uses: Scientific research. Group: Natural products. CAS No. 1076-22-8. Pack Sizes: 10 mM * 1 mL; 5 g; 25 g; 50 g. Product ID: HY-50723. | |
| 8-[(6-Amino)hexyl]-amino-cGMP - ATTO-655 | 8-[(6-Amino)hexyl]-amino-cGMP - ATTO-655, a fluorescent probe that selectively interacts with cyclic GMP, offers a unique opportunity to gain insights into the spatiotemporal regulation of this crucial second messenger in living cells. By illuminating the intricacies of cyclic GMP signaling, this probe promises to unlock the secrets of a wide range of diseases, from cardiovascular disorders to cancer. Witness the power of precision science with this cutting-edge technology. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 655, Triethylammonium salt. Grade: ≥ 95% by HPLC. Molecular formula: C16H26N7O7P - ATTO 655 (free acid). Mole weight: 968.39 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cGMP - ATTO-665 | 8-[(6-Amino)hexyl]-amino-cGMP - ATTO-665 is a fluorescent-labeled nucleotide used in biomedicine to study guanosine cyclic monophosphate (cGMP)-related signaling pathways. It has been used in studies looking at nitric oxide (NO) signaling and the cyclic GMP-protein kinase G (PKG) pathway, which are involved in regulating smooth muscle relaxation. Additionally, it has potential therapeutic applications in treating cardiovascular diseases and pulmonary hypertension. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 665. Grade: ≥ 95% by HPLC. Molecular formula: C16H26N7O7P - ATTO 665 (free acid). Mole weight: 1063.39 (free acid). | |
| 8-pCPT-PET-cGMP | 8-pCPT-PET-cGMP is an activator of cyclic GMP-dependent protein kinase as well as an inhibitor of the retinal type cGMP-gated ion channel, thus it can be used for distinction between kinase and ion channel mediated effects. It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Compared to 8-Br-PET-cGMP, 8-pCPT-PET-cGMP is much more lipophilic and membrane-permeant. Synonyms: 8- (4- Chlorophenylthio)- β- phenyl- 1, N2- ethenoguanosine- 3', 5'- cyclic monophosphate, sodium salt. Grade: ≥ 98% by HPLC. Molecular formula: C24H18ClN5O7PS · Na. Mole weight: 609.9. | |
| APN-C3-biotin | APN-C3-biotin is a heterobifunctional linker containing an APN moiety with exquisite chemoselectivity for cysteine and Biotin. The superior stability of APN-cysteine conjugates in aqueous media, human plasma, and living cells makes this new thiol-click reaction a promising methodology for applications in bioconjugation. Please contact us for GMP-grade inquiries. Synonyms: APN-C3-biotin; 2170240-97-6; CS-0254631; Rel-N-(4-((4-(cyanoethynyl)phenyl)amino)-4-oxobutyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide. Grade: 0.98. CAS No. 2170240-97-6. Molecular formula: C23H27N5O3S. Mole weight: 453.6. | |
| APPROVED Glycyltyrosine | APPROVED Glycyltyrosine is a dipeptide containing glycine and L-tyrosine. CAS No. 39630-46-1. Product ID: PAP-0008. Molecular formula: C11H16N2O5. Category: Amino acid. Product Keywords: Amino Acid Series; APPROVED Glycyltyrosine; PAP-0008; Amino acid; C11H16N2O5; 39630-46-1. Standard: GMP. Color: White to Off-White. Physical State: Solid. Solubility: DMSO (Slightly), Water (Slightly). Applications: APPROVED Glycyltyrosine is a drug that belongs to the class of drugs called psychostimulants. It is a non-amphetamine stimulant and does not produce amphetamine-like effects, such as euphoria or dependence. Product Description: APPROVED Glycyltyrosine is a drug that belongs to the class of drugs called psychostimulants. It is a non-amphetamine stimulant and does not produce amphetamine-like effects, such as euphoria or dependence. |  |
| Ataciguat | Ataciguat (HMR-1766) is a nitric oxide-independent soluble guanylate cyclase (sGC) activator. Ataciguat is able to activate the ferric heme-iron redox form of sGC that stimulate the production of cyclic GMP (cGMP). Ataciguat exhibits vasodilator effects[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HMR-1766. CAS No. 254877-67-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17500. | |
| Benzyl Mercaptan | Benzyl Mercaptan. Group: Biochemicals. Alternative Names: α-Toluenethiol (7CI,8CI); (Mercaptomethyl) benzene; Benzylthiol; GMP 800; NSC 41897; Phenylmethanethiol; Phenylmethyl Mercaptan; Thiobenzyl Alcohol; α-Mercaptotoluene; α-Toluolthiol; α-Tolyl Mercaptan. Grades: Highly Purified. CAS No. 100-53-8. Pack Sizes: 1g. Molecular Formula: C7H8S, Molecular Weight: 124.2. US Biological Life Sciences. | Worldwide |
| Biotin-EDA-PEG5-NHS | Biotin-EDA-PEG5-NHS enables simple an efficient biotinylation of antibodies, proteins and any other primary amine-containing biomolecules. NHS-activated biotin compound can react efficiently with primary amino groups (-NH2) to form stable, irreversible amide bonds. The hydrophilic PEG spacer arm imparts water solubility that is transferred to the biotinylated molecule. Please contact us for GMP-grade inquiries. Synonyms: Biotin-EDA-PEG5-NHS; BP-21744; (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[3-[2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethylamino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate. Grade: 0.98. Molecular formula: C30H49N5O12S. Mole weight: 703.8. | |
| Biotin-HPDP | Biotin-HPDP is a biochemical reagent. Biotin-HPDP can couple with GMPS and label free protein thiols. Biotin-HPDP can be used as a biological material or organic compound for life science related research [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 129179-83-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136769. | |
| Biotin-PEG11-Mal | Biotin-PEG11-Mal is a PEGylated biotin reagent PEG linker containing a maleimide (Mal) group.The maleimide gmoiety reacts specifically with sulfhydryl groups (at pH 6.5-7.5) to form a thioether linkage. The hydrophilic PEG spacer increases solubility in aqueous media of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules. Please contact us for GMP-grade inquiries. Synonyms: Biotin-PEG11-Mal; 1334172-60-9; N-(39-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-37-oxo-3,6,9,12,15,18,21,24,27,30,33-undecaoxa-36-azanonatriacontyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide; Biotin-PEG11-NH-Mal; 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-{35-[3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido]-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontan-1-yl}pentanamide; MFCD11041107; AKOS040743017; BP-21624. Grade: 0.98. CAS No. 1334172-60-9. Molecular formula: C41H71N5O16S. Mole weight: 922.1. | |
| Biotin-PEG11-oxyamine HCl salt | Biotin-PEG11-oxyamine is an aqueous soluble, aldehyde-reactive biotinylation reagent. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. Please contact us for GMP-grade inquiries. Synonyms: Biotin-PEG11-oxyamine; Biotin-PEG11-oxyamine HCl salt; Biotin-PEG11-oxyamine HCl; AKOS040743018; BP-22180; HY-140939; CS-0115624; 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-aminooxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]pentanamide. Grade: 0.98. Molecular formula: C34H66N4O14S. Mole weight: 787. | |
| Biotin-PEG23-amine | Biotin-PEG23-amine is long chain biotinylation molecule that is reactive to carboxyl groups or 5'phosphate groups to form stable amide bonds. It is water soluble and PEG spacer increases solubility in aqueous media of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules. Please contact us for GMP-grade inquiries. Synonyms: Biotin-PEG23-amine; 604786-74-5; Biotin-nPEG-amine; N-(71-Amino-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69-tricosaoxahenheptacontyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide; Biotin-dPEG?(23)-NH2; NH2-peg23-NH2 Biotinamide; MFCD21363310; AKOS040743027. Grade: 0.94. CAS No. 604786-74-5. Molecular formula: C58H114N4O25S. Mole weight: 1299.6. | |
| Biotin-PEG24-TFP ester | Biotin-PEG24-TFP ester is a monodisperse PEGylated biotinylation reagent that can couple with amine(-NH2) compound to form stable amide bonds. The hydrophilic PEG spacer arm imparts water solubility that is transferred to the biotinylated molecule. Please contact us for GMP-grade inquiries. Synonyms: Biotin-PEG12-TFP ester; 2055105-33-2; 2,3,5,6-tetrafluorophenyl 41-oxo-45-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-4,7,10,13,16,19,22,25,28,31,34,37-dodecaoxa-40-azapentatetracontanoate; Biotin-PEG12-TFPester; MFCD28385459; AKOS040743022; BP-22621; HY-140904. Grade: 0.98. CAS No. 2055105-33-2. Molecular formula: C67H117F4N3O28S. Mole weight: 1520.7. | |
| Biotin-PEG36-PFP ester | Biotin-PEG36-TFP ester is an aqueous soluble, PEGylated biotinylation reagent that can conjugate with amine molecule to form stable amide bonds. Please contact us for GMP-grade inquiries. Synonyms: Biotin-PEG36-PFP ester; 2353409-51-3; AKOS040743035; BP-24318; HY-140906; CS-0115922; Perfluorophenyl 113-oxo-117-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64,67,70,73,76,79,82,85,88,91,94,97,100,103,106,109-hexatriacontaoxa-112-azaheptadecahectanoate. Grade: 0.98. CAS No. 2353409-51-3. Molecular formula: C91H164F5N3O40S. Mole weight: 2067.4. | |
| Biotin-PEG3-(CH2)3-NH2 TFA salt | Biotin-PEG3-(CH2)3-NH2 TFA salt is a biotinylation reagent whicn can be coupled to carboxyl containing molecule or 5'phosphate groups to form stable amide bonds. Please contact us for GMP-grade inquiries. Synonyms: 1374658-86-2; Biotin-PEG3-C3-NH2; rel-N-(3-(2-(2-(3-Aminopropoxy)ethoxy)ethoxy)propyl)-5-((3aR,4R,6aS)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide; SCHEMBL23982462; DTXSID201104978; 5-[(3aR,4R,6aS)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-(3-{2-[2-(3-aminopropoxy)ethoxy]ethoxy}propyl)pentanamide; AKOS040741347; rel-(3aR,4R,6aS)-N-[3-[2-[2-(3-Aminopropoxy)ethoxy]ethoxy]propyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide. Grade: 0.98. CAS No. 1374658-86-2. Molecular formula: C20H38N4O5S. Mole weight: 446.6. | |
| Biotin-PEG6-NH-Boc | Biotin-PEG6-NH-Boc is a Biotin compound with a Boc protected amine moiety. Please contact us for GMP-grade inquiries. Synonyms: Biotin-PEG6-NH-Boc; 1292268-20-2; HY-W190945; BP-23614; CS-0254648; tert-butyl N-[2-[2-[2-[2-[2-[2-[2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate. Grade: 0.98. CAS No. 1292268-20-2. Molecular formula: C29H54N4O10S. Mole weight: 650.8. | |
| Biotin-PEG8-azide | Biotin-PEG8-azide is click chemistry reagent for biotinylation of macromolecule Please contact us for GMP-grade inquiries. Synonyms: Biotin-PEG8-azide; SCHEMBL21150837; 2363756-34-5; N-(26-Azido-3,6,9,12,15,18,21,24-octaoxahexacosyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide; BP-25110. Grade: 0.98. CAS No. 2363756-34-5. Molecular formula: C28H52N6O10S. Mole weight: 664.8. | |
| Biotin-PEG-azide, MW 1K-10K | Biotin-PEG-azide, MW 1,000 is a biotinylation reagent which has strong binding affinity to avidin or streptavidin. The azide moiety can react with terminal alkyne via copper click reaction or with cyclooctyne (BCN/DBCO) via copper-free click chemistry. Please contact us for GMP-grade inquiries. Synonyms: Biotin-PEG1-azide; 1204085-48-2; N-[2-(2-Azidoethoxy)ethyl]-biotinamide; BIOTIN-PEG-AZIDE; SCHEMBL23947625; DTXSID701118138; 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-[2-(2-azidoethoxy)ethyl]pentanamide; AKOS040756543. Molecular formula: C14H24N6O3S. Mole weight: 356.45. | |
| Biotin-PEG-Succinimidyl Valerate, MW 3.4K-5K | Biotin-PEG-Succinimidyl Valerate, MW 3,400 is a biotin PEGylation reagent with an NHS ester which is reactive specifically and efficiently with lysine and N-terminal amino groups at pH 7-9 to form a stable amide bond. Please contact us for GMP-grade inquiries. | |
| Calmodulin antagonist-1 | Calmodulin antagonist-1 is a calmodulin (CaM) antagonist that inhibits calmodulin-activated Ca2+-phosphodiesterase (PDE) (IC50 = 28 μM). Calmodulin antagonist-1 also inhibits trypsin-treated Ca2+-PDE (IC50 = 375 μM) in a competitive fashion with respect to cyclic GMP (Ki = 300 μM). Uses: Neoplasm inhibitor. Synonyms: N-(4-Aminobutyl)-5-chloro-1-naphthalenesulfonamide Hydrochloride; W8 Hydrochloride; N-(4-Aminobutyl)-5-chloro-1-naphthalenesulfonamide Monohydrochloride. Grade: ≥95%. CAS No. 78957-84-3. Molecular formula: C14H18Cl2N2O2S. Mole weight: 349.28. | |
| Carbazoquinocin B | It is produced by the strain of Streptomyces violaceus 2448-SVT2. It acts as an antioxidant and GMP phosphodiesterase inhibitor. IC50 is 0.12 mmol/L. CAS No. 155233-26-4. Molecular formula: C20H23NO2. Mole weight: 309.40. | |
| Carbazoquinocin C | It is produced by the strain of Streptomyces violaceus 2448-SVT2. It acts as an antioxidant and GMP phosphodiesterase inhibitor. IC50 is 0.22 mmol/L. Synonyms: SCHEMBL13424600. CAS No. 155233-27-5. Molecular formula: C20H23NO2. Mole weight: 309.40. | |
| Carbazoquinocin D | It is produced by the strain of Streptomyces violaceus 2448-SVT2. It acts as an antioxidant and GMP phosphodiesterase inhibitor. IC50 is 0.37 mmol/L. CAS No. 155233-28-6. Molecular formula: C21H25NO2. Mole weight: 323.43. | |
| Carbazoquinocin E | It is produced by the strain of Streptomyces violaceus 2448-SVT2. It acts as an antioxidant and GMP phosphodiesterase inhibitor. IC50 is 0.33 mmol/L. CAS No. 164177-49-5. Molecular formula: C21H25NO2. Mole weight: 323.43. | |
| Carbazoquinocin F | It is produced by the strain of Streptomyces violaceus 2448-SVT2. It acts as an antioxidant and GMP phosphodiesterase inhibitor. IC50 is 0.42 mmol/L. CAS No. 164177-50-8. Molecular formula: C22H27NO2. Mole weight: 337.45. | |
| cGAMP | cGAMP (Cyclic GMP-AMPP) functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. cGAMP activates stimulator of interferon genes (STING), which activates a signaling cascade leading to the production of type I interferons and other immune mediators [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Cyclic GMP-AMP; 3',3'-cGAMP. CAS No. 849214-04-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-12512. | |
Our database is helping our users find suppliers everyday.
