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| Product | Description | |
|---|---|---|
| 5-Fluorouracil | 25g Pack Size. Group: Biochemicals, Fluorinated Products. Formula: C4H3FN2O2. CAS No. 51-21-8. Prepack ID 22050130-25g. Molecular Weight 130.08. See USA prepack pricing. |  |
| 5-Fluorouracil | 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer [1] [2]. 5-Fluorouracil also inhibits HIV [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 5-FU. CAS No. 51-21-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 200 mg; 1 g; 5 g. Product ID: HY-90006. |  |
| 5-Fluorouracil | 5-Fluorouracil. Group: Biochemicals. Grades: Highly Purified. CAS No. 51-21-8. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C4H3FN2O2. US Biological Life Sciences. |  Worldwide |
| 5-Fluorouracil | 5-Fluorouracil Inhibitor. Uses: Scientific use. Product Category: T0984. CAS No. 51-21-8. |  |
| 5-Fluorouracil | Fluorouracil (5-Fluoracil, 5-FU) is a DNA/RNA synthesis inhibitor, which interrupts nucleotide synthetic by inhibiting thymidylate synthase (TS). Synonyms: 5-FU; Fluorouracil; Adrucil. Grades: >98%. CAS No. 51-21-8. Molecular formula: C4H3FN2O2. Mole weight: 130.08. |  |
| 5-Fluorouracil-13C,15N2 | 5-Fluorouracil- 13 C, 15 N 2 is the 13 C and 15 N labeled 5-Fluorouracil[1]. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer[2][3]. 5-Fluorouracil also inhibits HIV[4]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: 5-FU- 13 C, 15 N2. CAS No. 1189423-58-2. Pack Sizes: 1 mg. Product ID: HY-90006S1. | |
| 5-Fluorouracil-13C,15N2 | Labelled 5-FU, a potent antineoplastic agent in clinical use. Also an inhibitor of DNA synthesis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 5-Fluorouracil-15n2 | 5-Fluorouracil-15N2 is the 15N-labeled 5-Fluorouracil. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer. 5-Fluorouracil also inhibits HIV. Group: Inhibitors. CAS No. 68941-95-7. Molecular formula: C4H3FN2O2. Mole weight: 132.1. Appearance: Solid. Purity: 98 atom % 15N. Canonical SMILES: O=C1C(F)=C[15NH]C([15NH]1)=O. Catalog: ACM68941957. |  |
| 5-Fluorouracil-6-d1 | Labeled 5-FU, a potent antineoplastic agent in clinical use. Also an inhibitor of DNA synthesis. Group: Biochemicals. Alternative Names: 5-Fluoro-. Grades: Highly Purified. CAS No. 90344-84-6. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 5-Fluorouracil 99+% (HPLC) USP | 5-Fluorouracil 99+% (HPLC) USP. Group: Biochemicals. Grades: USP. CAS No. 51-21-8. Pack Sizes: 5g, 25g, 100g, 250g, 1Kg. US Biological Life Sciences. | Worldwide |
| 5-Fluorouracil (FU) | A potent antineoplastic agent in clinical use. Also an inhibitor of DNA synthesis. Group: Biochemicals. Alternative Names: FU. Grades: Highly Purified. Pack Sizes: 10g. US Biological Life Sciences. | Worldwide |
| 5-Fluorouracil N-b-D-glucuronide | 5-Fluorouracil N-b-D-glucuronide is a noteworthy pharmaceutical compound, acting as an illustrious glucuronidated derivative intricately intertwined with 5-Fluorouracil. It can be used in research of malignancies encompassing breast, colon and dermal cancer. Synonyms: 1-Deoxy-1-(5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-b-D-glucopyranuronic acid 5-Fluoro-1-(b-D-glucuronopyranosyl)uracil. CAS No. 66048-45-1. Molecular formula: C10H11FN2O8. Mole weight: 306.20. | |
| 5-Fluorouracil N- β-D-Glucuronide | 5-Fluorouracil N- β-D-Glucuronide is the N-glucuronide derivative of 5-Fluorouracil. 5-Fluorouracil N- β-D-Glucuronide unlike its O-glucuronide analog does not possess significant antitumor activity. Group: Biochemicals. Alternative Names: 1-Deoxy-1-(5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)- β-D-glucopyranuronic Acid; 5-Fluoro-1-( β -D-glucuronopyranosyl) uracil. Grades: Highly Purified. CAS No. 66048-45-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 5-Fluorouracil N- β-D-Glucuronide Methyl Ester, 2,3,4-Triacetate | Protected 5-Fluorouracil N- β-D-Glucuronide (F596010), a derivative of 5-Fluorouracil. 5-Fluorouracil N- β-D-Glucuronide unlike its O-glucuronide analog does not possess significant antitumor activity. Group: Biochemicals. Alternative Names: 1-Deoxy-1-(5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)- β-D-glucopyranuronic Acid Methyl Ester, 2,3,4-Triacetate. Grades: Highly Purified. CAS No. 77476-81-4. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| 5-Fluorouracil N-β-D-Glucuronide Methyl Ester, 2,3,4-Triacetate | Protected 5-Fluorouracil N-β-D-Glucuronide, a derivative of 5-Fluorouracil. 5-Fluorouracil N-β-D-Glucuronide unlike its O-glucuronide analog does not possess significant antitumor activity. Synonyms: 1-Deoxy-1-(5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-β-D-glucopyranuronic Acid Methyl Ester, 2,3,4-Triacetate. CAS No. 77476-81-4. Molecular formula: C17H19FN2O11. Mole weight: 446.34. | |
| 5-Fluorouracil (Standard) | 5-Fluorouracil (Standard) is the analytical standard of 5-Fluorouracil. This product is intended for research and analytical applications. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer [1] [2]. 5-Fluorouracil also inhibits HIV [3]. Uses: Scientific research. Group: Natural products. CAS No. 51-21-8. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-90006R. | |
| 2-Bromo-1,3-difluoropropane | 2-Bromo-1,3-difluoropropane is used in the preparation of 5-fluorouracil compounds as dUTPase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 2195-5-3. Pack Sizes: 50mg, 250mg. Molecular Formula: C3H5BrF2, Molecular Weight: 158.97. US Biological Life Sciences. | Worldwide |
| 2'-?Deoxy-?5-?[ (trimethylsilyl) ?ethynyl]?uridine 3,5-Dibenzoate | 2'-?Deoxy-?5-?[ (trimethylsilyl) ?ethynyl]?uridine 3,5-Dibenzoate is an protected intermediate in the synthesis of 5-Ethyl-2-deoxyuridine (E915020), a modulator of both antitumor action and pharmacokinetics of 5-Fluorouracil (F596000), a potent antineoplastic agent in clinical use. Group: Biochemicals. Grades: Highly Purified. CAS No. 140424-82-4. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| 3,5-Di-O-p-chlorobenzoyl-2'-deoxy a-5-fluorouridine | 3,5-Di-O-p-chlorobenzoyl-2'-deoxy a-5-fluorouridine. Group: Biochemicals. Alternative Names: 2'-Deoxy-3,5-di-O-p-chlorobenzoyl-a-D-ribofuranosyl-5-fluorouracil; 3,5-Di-O-p-chlorobenzoyl a-floxuridine; 1-[3,5-Bis-O-(4-chlorobenzoyl)-2-deoxy-a-D-erythro-pentofuranosyl]-5-fluoro-2,4(1H,3H)-pyrimidinedione. Grades: Highly Purified. CAS No. 110558-30-0. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C23H17Cl2FN2O7. US Biological Life Sciences. | Worldwide |
| 3,5-Di-O-p-chlorobenzoyl α, β-Floxuridine | Protected mixture of Floxuridine anomers. Group: Biochemicals. Alternative Names: 2'-Deoxy-3,5-di-O-p-chlorobenzoyl-α, β-D-ribofuranosyl-5-fluorouracil; 3,5-Di-O-p-chlorobenzoyl α, β-5-Fluoro-2'-deoxyuridine; 1-[3,5-Bis-O-(4-chlorobenzoyl)-2-deoxy-α, β-D-erythro-pentofuranosyl]-5-fluoro-2,4(1H,3H)-pyrimidinedione. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 3,5-Di-O-p-chlorobenzoyl α,β-Floxuridine | Protected mixture of Floxuridine anomers. Synonyms: 2'-Deoxy-3,5-di-O-p-chlorobenzoyl-α,β-D-ribofuranosyl-5-fluorouracil; 3,5-Di-O-p-chlorobenzoyl α,β-5-Fluoro-2'-deoxyuridine; 1-[3,5-Bis-O-(4-chlorobenzoyl)-2-deoxy-α,β-D-erythro-pentofuranosyl]-5-fluoro-2,4(1H,3H)-pyrimidinedione. Molecular formula: C23H17Cl2FN2O7. Mole weight: 523.29. | |
| 3,5-Di-O-p-chlorobenzoyl α, β-Floxuridine-13C,15N2 | Protected mixture of labeled Floxuridine anomers. Group: Biochemicals. Alternative Names: 2'-Deoxy-3,5-di-O-p-chlorobenzoyl-α, β-D-ribofuranosyl-5-fluorouracil-13C,15N2; 3,5-Di-O-p-chlorobenzoyl α, β-5-Fluoro-2'-deoxyuridine-13C,15N2; 1-[3,5-Bis-O-(4-chlorobenzoyl)-2-deoxy-α, β-D-erythro-pentofuranosyl]-5-fluoro-2,4(1H,3H)-pyrimidinedione-13C,15N2. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 3,5-Di-O-p-chlorobenzoyl α-floxuridine | Heterocyclic Organic Compound. Alternative Names: 2'-Deoxy-3,5-di-O-p-chlorobenzoyl-α-D-ribofuranosyl-5-fluorouracil; 3,5-Di-O-p-chlorobenzoyl α-5-Fluoro-2'-deoxyuridine; 1-[3,5-Bis-O-(4-chlorobenzoyl)-2-deoxy-α-D-erythro-pentofuranosyl]-5-fluoro-2,4(1H,3H)-pyrimidinedione. CAS No. 110558-30-0. Molecular formula: C23H17Cl2FN2O7. Mole weight: 523.29. Purity: 0.96. IUPACName: [(2R,3R,5S)-3-(4-chlorobenzoyl)oxy-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl 4-chlorobenzoate. Canonical SMILES: C1C (C (OC1N2C=C (C (=O)NC2=O)F)COC (=O)C3=CC=C (C=C3)Cl)OC (=O)C4=CC=C (C=C4)Cl. Catalog: ACM110558300. | |
| 3,5-Di-O-p-chlorobenzoyl α-Floxuridine | Protected α-anomer of Floxuridine. Group: Biochemicals. Alternative Names: 2'-Deoxy-3,5-di-O-p-chlorobenzoyl-α-D-ribofuranosyl-5-fluorouracil; 3,5-Di-O-p-chlorobenzoyl α-5-Fluoro-2'-deoxyuridine; 1-[3,5-Bis-O-(4-chlorobenzoyl)-2-deoxy-α-D-erythro-pentofuranosyl]-5-fluoro-2,4(1H,3H)-pyrimidinedione. Grades: Highly Purified. CAS No. 110558-30-0. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 3,5-Di-O-p-chlorobenzoyl α-Floxuridine | Protected Floxuridine α-anomer. Synonyms: 2'-Deoxy-3,5-di-O-p-chlorobenzoyl-α-D-ribofuranosyl-5-fluorouracil; 3,5-Di-O-p-chlorobenzoyl α-5-Fluoro-2'-deoxyuridine; 1-[3,5-Bis-O-(4-chlorobenzoyl)-2-deoxy-α-D-erythro-pentofuranosyl]-5-fluoro-2,4(1H,3H)-pyrimidinedione. CAS No. 110558-30-0. Molecular formula: C23H17Cl2FN2O7. Mole weight: 523.29. | |
| 3,5-Di-O-p-chlorobenzoyl α-Floxuridine-13C,15N2 | Protected α-anomer of labeled Floxuridine. Group: Biochemicals. Alternative Names: 2'-Deoxy-3,5-di-O-p-chlorobenzoyl-α-D-ribofuranosyl-5-fluorouracil-13C,15N2; 3,5-Di-O-p-chlorobenzoyl α-5-Fluoro-2'-deoxyuridine-13C,15N2; 1-[3,5-Bis-O-(4-chlorobenzoyl)-2-deoxy-α-D-erythro-pentofuranosyl]-5-fluoro-2,4(1H,3H)-pyrimidinedione-13C,15N2. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 4-DAMP | 4-DAMP (4-DAMP methiodide) is a potent and selective antagonist of M3 receptors and also has a high affinity for the closely-related M5 receptors. 4-DAMP combined with 5-Fluorouracil (5-Fu) (HY-90006) could significantly reduce the cell viability and enhance apoptosis in MKN45 and BGC823 gastric cancer cells. 4-DAMP inhibits lipopolysaccharide (LPS)- and tobacco-induced pulmonary inflammation and reduces mucin 5AC (MUC5AC), oligomeric mucus/gel-forming secretion [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4-DAMP methiodide. CAS No. 1952-15-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100958. | |
| 5'-(3-MAL-PEG2-aminobutanoate)-floxuridine | A derivative of Floxuridine. Floxuridine is a prodrug that is rapidly catabolized in vivo to 5-fluorouracil when administered by rapid injection. Synonyms: 5'-(3-MAL-PEG2-aminobutanoate)-floxuridine. Grades: > 95%. Molecular formula: C29H42FN5O13. Mole weight: 687.68. | |
| 5-Ethyl-2-deoxyuridine | 5-Ethyl-2-deoxyuridine was found to be a modulator of both antitumor action and pharmacokinetics of 5-Fluorouracil (F596000), a potent antineoplastic agent in clinical use. Group: Biochemicals. Alternative Names: 2'-Deoxy-5-ethyluridine; 5-Ethyl-1-(2'-deoxy- β-D-ribofuranosyl)uracil; 5-Ethyl-2'-deoxyuridine; 5-Ethyldeoxyuridine; Aedurid; EDU; EUDR; Edoxudine; Epoxudine; ORF 15817; RWJ 15817; β-5-Ethyl-2'-deoxyuridine; β-5-Ethyldeoxyuridine. Grades: Highly Purified. CAS No. 15176-29-1. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 5-Ethyl-2'-deoxyuridine-d5 | Isotope labelled 5-Ethyl-2'-deoxyuridine was found to be a modulator of both antitumor action and pharmacokinetics of 5-Fluorouracil, a potent antineoplastic agent in clinical use. Synonyms: 2'-Deoxy-5-ethyluridine-d5; 5-Ethyl-1-(2'-deoxy-β-D-ribofuranosyl)uracil-d5; 5-Ethyl-2'-deoxyuridine-d5; 5-Ethyldeoxyuridine-d5; Aedurid-d5; EDU-d5; EUDR-d5; Edoxudine-d5; Epoxudine-d5; ORF 15817-d5; RWJ 15817-d5; β-5-Ethyl-2'-deoxyuridine-d5; β-5-Ethyldeoxyuridine-d5. Molecular formula: C11H11D5N2O5. Mole weight: 261.29. | |
| 5-Ethyl-2-deoxyuridine-d5 | Isotope labelled 5-Ethyl-2-deoxyuridine was found to be a modulator of both antitumor action and pharmacokinetics of 5-Fluorouracil (F596000), a potent antineoplastic agent in clinical use. Group: Biochemicals. Alternative Names: 2'-Deoxy-5-ethyluridine-d5; 5-Ethyl-1-(2'-deoxy- β-D-ribofuranosyl)uracil-d5; 5-Ethyl-2'-deoxyuridine-d5; 5-Ethyldeoxyuridine-d5; Aedurid-d5; EDU-d5; EUDR-d5; Edoxudine-d5; Epoxudine-d5; ORF 15817-d5; RWJ 15817-d5; β-5-Ethyl-2'-deoxyuridine-d5; β-5-Ethyldeoxyuridine-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 5-Fluoro-1-(b-L-ribofuranosyl)-uracil | 5-Fluoro-1-(b-L-ribofuranosyl)-uracil is a powerful antineoplastic compound, exhibiting immense potential in research of diverse malignancies. Renowned for its impact on inhibiting DNA enhancement and impeding cell proliferation, this remarkable compound emerges as an invaluable asset in the research and development of oncology. Synonyms: 1-beta-L-Ribofuranosyl-5-fluorouracil; L-5-Fluorouridine; 1-[(2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-fluoro-pyrimidine-2,4-dione; 5-Fluoro-1-(β-L-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione; L-β-Ribofuranosyl-5'-fluorouracil. Grades: 95%. CAS No. 77210-26-5. Molecular formula: C9H11FN2O6. Mole weight: 262.19. | |
| 5-Fluoro-2-ethoxy-4(1H)pyrimidinone | Fluorouracil Impurity F is a derivative of 5-fluorouracil. Uses: Ethoxy-5-fluoro-4(3h)-pyrimidinone (fluorouracil ep impurity f) is a derivative of 5-fluorouracil (3c,15n2 labelled, f596002) which is a potent antineoplastic agent in clinical use. Synonyms: 2-ethoxy-5-fluoro-1H-pyrimidin-6-one. Grades: > 95 %. CAS No. 56177-80-1. Molecular formula: C6H7FN2O2. Mole weight: 158.13. | |
| 5-Fluoro-6-hydroxyhydro Uracil (Mixture of Diastereomers) | An impurity of 5-Fluorouracil. Group: Biochemicals. Alternative Names: 5-Fluorodihydro-6-hydroxy-2,4(1H,3H)-pyrimidinedione; NSC 528189. Grades: Highly Purified. CAS No. 37103-91-6. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| 5-Fluorodi hydropyrimidine-2, 4-dione-13C, 15N2 | A labeled metabolite of 5-Fluorouracil. Group: Biochemicals. Alternative Names: 5,6-Dihydro-5-fluorouracil-13C,15N2; 5-Fluoro-5,6-dihydrouracil-13C,15N2; 5-Fluorodihydrouracil-13C,15N2; 5-Fluorohydrouracil-13C,15N2; 5-DHFU-13C,15N2. Grades: Highly Purified. CAS No. 1189492-99-6. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| 5-Fluoroorotic Acid Monohydrate (FOA, 5-FOA) | Useful in the identification and selection of the strains of Saccharomyces cerevisiae that contain the mutant ura3- gene. 5-FOA is toxic to yeast cells that can synthesize the enzyme orotidine-5-phosphate decarboxylase and are therefore unable to grow on 5-FOA-containing media. Group: Biochemicals. Alternative Names: FOA; 5-FOA; 5-Fluoroorotate; 5-FLUORO-4-PYRIMIDINECARBOXYLIC ACID; 5-FLUORO-1,2,3,6-TETRAHYDRO-2,6-DIOXO-(9CI); 1,2,3,6-TETRAHYDRO-2,6-DIOXO-5-FLUORO-4- PYRIMIDINECARBOXYLIC ACID; 2,6-Dihydroxy-5-fluoropyrimidine-4-carboxylic acid; 5-Fluorouracil-4-carboxylic acid. Grades: Molecular Biology Grade. CAS No. 207291-81-4,220141-70-8,703-95-7. Pack Sizes: 500mg, 1g, 10g, 25g, 50g, 100g. US Biological Life Sciences. | Worldwide |
| 5-Fluorouridine-5'-monophosphate sodium salt | 5-fluorouridine 5'-monophosphate is a pyrimidine ribonucleoside 5'-monophosphate having 5-fluorouracil as the pyrimidine component. It has a role as a drug metabolite. It is a pyrimidine ribonucleoside 5'-monophosphate and an organofluorine compound. It derives from a uridine 5'-monophosphate. Synonyms: 5F-UMP. Molecular formula: C9H12FN2O9P. Mole weight: 342.17 (free acid). | |
| 5-Fluorouridine-5'-triphosphate triethylammonium salt | 5-Fluorouridine-5'-triphosphate triethylammonium salt, an indispensable compound within the field of biomedicine, serves as a pivotal reagent. Its essence lies in its ability to serve as a substrate for RNA synthesis, permitting the infusion of the vital anticancer agent, 5-fluorouracil, into RNA molecules. Synonyms: Uridine 5'-(tetrahydrogen triphosphate),5-fluoro-,compd with N,N-diethylethanamine(1:3)(9CI). Grades: 95%. Molecular formula: C33H74N6O15P3F. Mole weight: 906.89. | |
| 5-Fluorouridine (Standard) | 5-Fluorouridine (Standard) is the analytical standard of 5-Fluorouridine. This product is intended for research and analytical applications. 5-Fluorouridine, a metabolite of 5-fluorouracil (HY-90006), is a potent ribozyme self-cleavage inhibitor. 5-Fluorouridine incorporates into both total and poly A RNA and has antiproliferative activity. 5-Fluorouridine induces apoptosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 316-46-1. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-107856R. | |
| 5-(Hydroxymethyl)-2'-deoxyuridine | 5-(Hydroxymethyl)-2'-deoxyuridine is a nucleoside analog with anticancer and antiviral activities. It inhibits the replication of murine S180 lung carcinoma cells and Ehrlich ascites mammary carcinoma cells (ED50s = 8.5 and 4 μM, respectively) and multiple human leukemia cell lines (IC50s = 1.7-5.8 μM). 5-(Hydroxymethyl)-2'-deoxyuridine acts synergistically with 5-fluorouracil (5-FU) against HT-29, HCT116, PANC-1, and EKVX cancer cells with no effect on WI38 embryonic lung fibroblasts. Uses: Antineoplastic agents. Synonyms: a-hydroxythymidine; 5-Hydroxymethyl-2'-deoxyuridine; alpha-Hydroxythymidine; 5-Hydroxymethyldeoxyuridine; HMdU; 5-HMdU; 2'-Deoxy-5-(hydroxymethyl)uridine; 1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-5-(2-hydroxymethyl)pyrimidine-2,4(1H,3H)-dione. Grades: ≥95%. CAS No. 5116-24-5. Molecular formula: C10H14N2O6. Mole weight: 258.23. | |
| 5'-O-DMT-5-Fluoro-2'-deoxyuridine-3'-CE Phosphoramidite | 5'-O-DMT-5-Fluoro-2'-deoxyuridine-3'-CE Phosphoramidite is a highly potent reagent for the synthesis of 5-fluorouracil (5-FU) containing oligonucleotides, with potential applications in the treatment of cancer. By boosting the selectivity and efficacy of 5-FU, a well-established chemotherapy drug for different forms of cancer, this compound constitutes a promising avenue to enhance the therapeutic options available to patients. Synonyms: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-fluoro-, 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-fluoro-uridine 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]; FdU-amidite; NSC-729744. Grades: ≥98% by HPLC. CAS No. 142246-63-7. Molecular formula: C39H46FN4O8P. Mole weight: 748.78. | |
| Eniluracil | Eniluracil (5-Ethynyluracil) is an orally active dihydropyrimidine dehydrogenase ( DPD ) inhibitor. Eniluracil irreversibly inhibits DPD , increases the oral bioavailability of 5-fluorouracil to 100%, and facilitates the uniform absorption and toxicity of 5-fluorouracil. Eniluracil can be used in cancer research of combination with fluoropyrimidines (including 5-fluorouracil) [1] [2]. Eniluracil is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 5-Ethynyluracil; GW776C85. CAS No. 59989-18-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10533. | |
| Eniluracil | Eniluracil, also known as GW776 and GW776C85, is an orally active and irreversible inhibitor of dihydropyrimidine dehydrogenase. Eniluracil inhibits dihydropyrimidine dehydrogenase, the rate-limiting enzyme that catabolizes and inactivates 5-fluorouracil (5-FU) in the liver. Co-administration of ethynyluracil permits the oral administration of 5-FU. Uses: Enzyme inhibitors. Synonyms: 5-ethynyluracil; 5-ethynylpyrimidine-2,4(1H,3H)-dione; 5-Ethynyl-2-hydroxypyrimidin-4(1H)-one; GW776; GW-776; GW 776. CAS No. 59989-18-3. Molecular formula: C6H4N2O2. Mole weight: 136.11. | |
| Floxuridine | Floxuridine (5-Fluorouracil 2'-deoxyriboside) is a pyrimidine analog and known as an oncology antimetabolite. Floxuridine inhibits Poly(ADP-Ribose) polymerase and induces DNA damage by activating the ATM and ATR checkpoint signaling pathways in vitro. Floxuridine is a extreamly potent inhibitor for S. aureus infection and induces cell apoptosis [1] [2]. Floxuridine has antiviral effects against HSV and CMV [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 5-Fluorouracil 2'-deoxyriboside. CAS No. 50-91-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B0097. | |
| Floxuridine | Floxuridine (5-Fluorouracil 2'-deoxyriboside) is a pyrimidine analog and known as an oncology antimetabolite. Floxuridine inhibits Poly(ADP-Ribose) polymerase and induces DNA damage by activating the ATM and ATR checkpoint signaling pathways in vitro. Floxuridine is a extreamly potent inhibitor for S. aureus infection and induces cell apoptosis. Floxuridine has antiviral effects against HSV and CMV. Group: Inhibitors. Alternative Names: 1-beta-d-2'-deoxyribofuranosyl-5-flurouracil;1beta-D-2-Deoxyribofuranosyl-5-fluorouracil;2'-deoxy-5-fluoro-uridin;5-fluor-1-(beta-2'-deoxyribofuranosyl)pyrimidin-2,4(1h,3h)-dion;5-Fluor-1-(beta-2-deoxyribofuranosyl)pyrimidin-2,4(1H,3H)-dion;5-Fluoro-2-deoxyiridine;5-Fluorouracil 2-deoxyriboside;5-Fluorouracil deoxyriboside. CAS No. 50-91-9. Molecular formula: C9H11FN2O5. Mole weight: 246.19. Purity: 0.9995. Catalog: ACM50919. | |
| Floxuridine | Floxuridine is an antineoplastic antimetabolite, used in the treatment of colon carcinoma and colorectal cancer that has metastasized to the liver. Synonyms: Deoxyfluorouridine; FDUR; NSC 27640; NSC27640; NSC-27640; 2'-Deoxy-5-fluorouridine; 1-(2-Deoxy-β-D-ribofuranosyl)-5-fluorouracil; 5-Fluoro-2'-deoxy-uridine; 5-Fluorodeoxyuridine; 5-Fluorouracil 2'-Deoxyriboside; FdUrd. Grades: ≥95%. CAS No. 50-91-9. Molecular formula: C9H11FN2O5. Mole weight: 246.19. | |
| Levoleucovorin Calcium | Levoleucovorin Calcium (Calcium levofolinate) is the active form of calcium Folinic acid (HY-13664) and has anti-tumor effects. Levoleucovorin Calcium is also a potentiator of the anti-cancer toxicity of 5-Fluorouracil (HY-90006) [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Calcium levofolinate; CL307782. CAS No. 80433-71-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 2 g. Product ID: HY-13667. | |
| Methyl 1-(5-fluoro-1H-2-oxopyrimidin-4-yl)-b-D-glucopyranuronate | Methyl 1-(5-fluoro-1H-2-oxopyrimidin-4-yl)-b-D-glucopyranuronate is an esteemed biomedical compound, used to study and subdue diverse DNA viruses. Synonyms: FU-O-G; 5-FU O-beta-D-glucuronide; 5-Fluorouracil O-beta-D-glucuronide; methyl(2S,3S,4S,5R,6S)-6-[(5-fluoro-2-oxo-1H-pyrimidin-6-yl)oxy]-3,4,5-trihydroxyoxane-2-carboxylate. CAS No. 64977-52-2. Molecular formula: C11H13FN2O8. Mole weight: 320.23. | |
| N6-Cyclopentyladenosine | N6-Cyclopentyladenosine (CPA) is a selective Adenosine A 1 receptor agonist, with K i values of 2.3 nM, 790 nM and 43 nM for human A 1 , A 2A and A 3 receptors, respectively. N6-cyclopentyladenosine increases Apoptosis. N6-Cyclopentyladenosine has antitumor activity against leukemia. N6-cyclopentyladenosine improves 5-fluorouracil (HY-90006)-induced hematopoietic damage, regulates sleep, and delays Aminophylline-induced clonic epileptic seizures [1] [2] [3] [4] [5] [6] [7] [8] [9]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CPA; UK-80882. CAS No. 41552-82-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103181. | |
| Oxonic acid potassium salt | Oxonic acid potassium salt is an inhibitor of uricase. It has been used for the inhibition of 5-fluorouracil-induced gastrointestinal toxicity without the loss of its antitumor activity in rats. It has also been used to induce hyperuricemia in rats; as it inhibits uric acid metabolism. Synonyms: potassium;4,6-dioxo-1H-1,3,5-triazine-2-carboxylate. Grades: > 98 %. CAS No. 2207-75-2. Molecular formula: C4H2KN3O4. Mole weight: 195.17. | |
| Uridine triacetate | Uridine triacetate (Tri-O-acetyl uridine) is an orally active proagent of Uridine (HY-B1449). Uridine triacetate is quickly absorbed in the gut, and is rapidly deacetylated in the circulation to yield free uridine. Uridine triacetate is used for the research of 5-fluorouracil (5-FU) and capecitabine toxicity, or early-onset cardiac or central nervous system (CNS) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tri-O-acetyl uridine. CAS No. 4105-38-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-14905. | |
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