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| Product | Description | |
|---|---|---|
| 5-HT3 antagonist 1 | A potent and selective antagonist of serotonin 3 (5-HT3) receptor. Synonyms: 1H-1,4-Diazepine, 1H-indazole-3-carboxamide deriv. CAS No. 129294-09-3. Molecular formula: C22H27N5O. Mole weight: 377.48. |  |
| 5-HT3 antagonist 2 | 5-HT3 antagonist 2 is a 5-HT3 receptor antagonist. Synonyms: Spiro[1-azabicyclo[2.2.2]?octane-3,?5'(4'H)?-oxazole]?, 2'-(1-methyl-1H-indol-3-yl)?-. CAS No. 128199-93-9. Molecular formula: C18H21N3O. Mole weight: 295.38. | |
| 5-HT3 antagonist 3 | 5-HT3 antagonist 3 is a compound which can be used to treat gastro intestinal functional disorders in the lower intestinal tracts extracted from patent DE 4238553 A1. 5-HT3 antagonist 3 is a high-affinity 5-HT3 receptor antagonist. 5-HT3 antagonist 3 binds to 5-HT3 receptors in rat brain cortical membranes with Ki of 0.25 nM. Synonyms: Imidazol-1-yl compound 1; 10-((2-methyl-1H-imidazol-1-yl)methyl)-5,6,9,10-tetrahydro-4H-pyrido[3,2,1-jk]carbazol-11(8H)-one. CAS No. 120635-47-4. Molecular formula: C20H21N3O. Mole weight: 319.40. | |
| 5-HT3 antagonist-4i | 5-HT3 antagonist-4i is a 5-HT3 receptor (5HT3R) antagonist. It modulates the serotonergic system. Synonyms: 4i; 5-HT3 antagonist 4. CAS No. 930478-88-9. Molecular formula: C16H12ClN3O. Mole weight: 297.74. | |
| 5-HT3 antagonist 5 | 5-HT3 antagonist 5 is a 5-HT3 receptor antagonist with anti-depressant activity. Synonyms: N-(4-methoxyphenyl)-2-quinoxalinecarboxamide. CAS No. 901599-43-7. Molecular formula: C16H13N3O2. Mole weight: 279.29. | |
| 5-HT3 antagonist 5 | 5-HT3 antagonist 5 is a quinoxalin-2-carboxamide compound, a 5-HT 3 receptor antagonist. 5-HT3 antagonist 5 exerts antagonism on 5-HT 3 agonist and 2-methyl-5-HT , and shows anti-depressant effect in mice [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 901599-43-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148038. |  |
| 1,2,3,3',4,4'-Hexahydro-[1,1'-binaphthalene]-8,8'-dicarboxylic Acid | 1,2,3,3',4,4'-Hexahydro-[1,1'-binaphthalene]-8,8'-dicarboxylic Acid is an impurity of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Molecular formula: C22H20O4. Mole weight: 348.40. | |
| 1,4-Dimethyl-2,6-piperazinediacetic Acid Dimethyl Ester | 1,4-Dimethyl-2,6-piperazinediacetic Acid Dimethyl Ester is an intermediate in the synthesis of Indisetron (I532500), which is a 5-HT3 receptor antagonist as an antiemetic agent. It is used for treatment of digestive tract disorders. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C12H22N2O4. US Biological Life Sciences. |  Worldwide |
| 1-Methylindole | An impurity of Ramosetron.Ramosetron is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting. Synonyms: 1-methylindole. Grade: > 95 %. CAS No. 603-76-9. Molecular formula: C9H9N. Mole weight: 131.17. | |
| 1-Methylindole-3-carboxylic acid | An impurity of Ramosetron.Ramosetron is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting. Synonyms: 1-methylindole-3-carboxylic acid. Grade: > 95 %. CAS No. 32387-21-6. Molecular formula: C10H9NO2. Mole weight: 175.18. | |
| 1-Methylisatin | An impurity of Ramosetron.Ramosetron is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting. Synonyms: 1-methylindole-2,3-dione. Grade: > 95 %. CAS No. 2058-74-4. Molecular formula: C9H7NO2. Mole weight: 161.16. | |
| (1S)-N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-1,2,3,4-tetrahydro-1-naphthalenecarboxamide | (1S)-N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-1,2,3,4-tetrahydro-1-naphthalenecarboxamide is an intermediate of Palonosetron. Palonosetron (INN, trade name Aloxi) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: (S)-N-((R)-quinuclidin-3-yl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide; 1-Naphthalenecarboxamide, N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-1,2,3,4-tetrahydro-, (1S)-. Molecular formula: C18H24N2O. Mole weight: 284.40. | |
| (1S)-N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-1,2,3,4-tetrahydro-1-naphthalenecarboxamide | (1S)-N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-1,2,3,4-tetrahydro-1-naphthalenecarboxamide is an intermediate of Palonosetron. Palonosetron (INN, trade name Aloxi) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Uses: Palonosetron intermediate. Synonyms: [S-(R*,R*)]-N-1-Azabicyclo[2.2.2]oct-3-yl-1,2,3,4-tetrahydro-1-naphthalenecarboxamide; (S)-N-((S)-quinuclidin-3-yl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide; 1-Naphthalenecarboxamide, N-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-1,2,3,4-tetrahydro-, (1S)-; Palonosetron Impurity 4. Grade: ≥95%. CAS No. 177793-79-2. Molecular formula: C18H24N2O. Mole weight: 284.40. | |
| 2- [1- (4-Piperonyl) piperazinyl] benzothiazole | 5-HT4 receptor agonist with moderate activity as a 5-HT3 antagonist. Has no affinity at 5-HT1 or dopamine D2 receptors. Potential gastrokinetic agent. Group: Biochemicals. Grades: Purified. CAS No. 155106-73-3. Pack Sizes: 10mg, 50mg. Molecular Formula: C19H19N3O2S. US Biological Life Sciences. | Worldwide |
| 2-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-2,4,5,6-tetrahydro-1H-benz[de]isoquinolin-1-one Hydrochloride | 2-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-2,4,5,6-tetrahydro-1H-benz[de]isoquinolin-1-one Hydrochloride is an intermediate in the synthesis of Palonosteron (P165805), an serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting. Group: Biochemicals. Grades: Highly Purified. CAS No. 135729-66-7. Pack Sizes: 5mg, 10mg. Molecular Formula: C19H23ClN2O. US Biological Life Sciences. | Worldwide |
| 2-Aminomethyl-4-(4-fluorobenzyl)morpholine | 2-Aminomethyl-4-(4-fluorobenzyl)morpholine is an intermediate of Mosapride, which is a selective agonist of 5-HT4 receptor, could be used as an astroprokinetic agent. It is also found to be a 5-HT3 receptor antagonist. Uses: Mosapride intermediate. Synonyms: 4-[(4-Fluorophenyl)methyl]-2-morpholinemethanamine; 1-[4-(4-Fluorobenzyl)-2-morpholinyl]methanamine; 1-[4-(4-Fluorobenzyl)morpholin-2-yl]methanamine; 2-Morpholinemethanamine, 4-[(4-fluorophenyl)methyl]-. Grade: ≥95%. CAS No. 112914-13-3. Molecular formula: C12H17FN2O. Mole weight: 224.27. | |
| (2E,2'E)-4,4'-(Methylimino)bis-2-butenoic Acid Dimethyl Ester | (2E,2'E)-4,4'-(Methylimino)bis-2-butenoic Acid Dimethyl Ester is an intermediate in the synthesis of Indisetron (I532500), which is a 5-HT3 receptor antagonist as an antiemetic agent. It is used for treatment of digestive tract disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 852052-29-0. Pack Sizes: 50mg, 100mg. Molecular Formula: C11H17NO4. US Biological Life Sciences. | Worldwide |
| 2-Methylimidazole | An impurity of Ondansetron, which is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic. Synonyms: Ondansetron EP Impurity F; 2-Methyl imidazole; 1H-Imidazole, 2-methyl-; Imidazole, 2-methyl-. CAS No. 693-98-1. Molecular formula: C4H6N2. Mole weight: 82.1. | |
| 2-((S)-Quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinoline | 2-((S)-Quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinoline is an intermediate in the synthesis of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: 2-[(3S)-1-Azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinoline; 1H-Benz[de]isoquinoline, 2-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-; Palonosetron Impurity 15. Grade: ≥95%. CAS No. 1796933-62-4. Molecular formula: C19H26N2. Mole weight: 282.42. | |
| 3a,4,5,6-Tetrahydro-1H,3H-naphtho[1,8-cd]pyran-1-one | 3a,4,5,6-Tetrahydro-1H,3H-naphtho[1,8-cd]pyran-1-one is an intermediate in the synthesis of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: 3a,4,5,6-tetrahydro-1H,3H-benzo[de]isochromen-1-one; 1H,3H-Naphtho[1,8-cd]pyran-1-one, 3a,4,5,6-tetrahydro-; Palonosetron Impurity 55. CAS No. 81603-30-7. Molecular formula: C12H12O2. Mole weight: 188.22. | |
| 3-Aminomethyl-4-(4-fluorobenzyl)morpholine | 3-Aminomethyl-4-(4-fluorobenzyl)morpholine is an impurity of Mosapride, which is a selective agonist of 5-HT4 receptor, could be used as an astroprokinetic agent. It is also found to be a 5-HT3 receptor antagonist. Uses: Mosapride (a616180) impurity. Synonyms: 4-[(4-Fluorophenyl)methyl]-3-morpholinemethanamine. Grade: ≥95%. CAS No. 174561-70-7. Molecular formula: C12H17FN2O. Mole weight: 224.27. | |
| 3-AQC | 3-AQC has been found to be a competitive 5-HT3 antagonist with widely differing activity in various tissues. Synonyms: 2-Quinoxalinecarbonitrile, 3-[4-(2-propen-1-yl)-1-piperazinyl]-, (2Z)-2-butenedioate (1:1); 3 AQC; 3AQC; 3-(4-Allylpiperazin-1-yl)-2-quinoxalinecarbonitrile maleate; 2-Quinoxalinecarbonitrile, 3-[4-(2-propenyl)-1-piperazinyl]-, (2Z)-2-butenedioate (1:1); 2-Quinoxalinecarbonitrile, 3-[4-(2-propenyl)-1-piperazinyl]-, (Z)-2-butenedioate (1:1); 3-(4-allylpiperazin-1-yl)quinoxaline-2-carbonitrile maleate. Grade: ≥95% by HPLC. CAS No. 201216-42-4. Molecular formula: C16H17N5.C4H4O4. Mole weight: 395.42. | |
| 3-Bromo-7-methoxy-1H-indazole | 3-Bromo-7-methoxy-1H-indazole is an intermediate in the synthesis of 7-Hydroxy Granisetron (H942675), a metabolite of Granisetron (G780000), a specific serotonin (5HT3) receptor antagonist. Used as an antiemetic. Granisetron HCl is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptor. Group: Biochemicals. Grades: Highly Purified. CAS No. 133841-06-2. Pack Sizes: 250mg, 2.5g. Molecular Formula: C8H7BrN2O, Molecular Weight: 227.06. US Biological Life Sciences. | Worldwide |
| (3S)-Aminoquinuclidine Dihydrochloride | (3S)-Aminoquinuclidine Dihydrochloride is an intermediate in the synthesis of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Uses: Palonosetron intermediate. Synonyms: (S)-quinuclidin-3-amine dihydrochloride; (3S)-1-Azabicyclo[2.2.2]octan-3-amine Hydrochloride (1:2); (3S)-3-Amino-1-azabicyclo[2.2.2]octane Dihydrochloride; (3S)-quinuclidin-3-amine Dihydrochloride; 1-Azabicyclo[2.2.2]octan-3-amine, (3S)-, hydrochloride (1:2). Grade: ≥95%. CAS No. 119904-90-4. Molecular formula: C7H16Cl2N2. Mole weight: 199.12. | |
| (3S)-N-[[(1S)-1,2,3,4-Tetrahydro-1-naphthalenyl]methyl]-1-azabicyclo[2.2.2]octan-3-amine | (3S)-N-[[(1S)-1,2,3,4-Tetrahydro-1-naphthalenyl]methyl]-1-azabicyclo[2.2.2]octan-3-amine is an intermediate of Palonosetron. Palonosetron (INN, trade name Aloxi) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Uses: Palonosetron intermediate. Synonyms: [S-(R*,R*)]-N-[(1,2,3,4-Tetrahydro-1-naphthalenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine; (S)-N-(((S)-1,2,3,4-tetrahydronaphthalen-1-yl)methyl)quinuclidin-3-amine; Palonosetron Impurity 5. Grade: ≥95%. CAS No. 177793-80-5. Molecular formula: C18H26N2. Mole weight: 270.41. | |
| 4,5,6,7-Tetrahydro-1H-benzoimidazole-5-carboxylic Acid | An impurity of Ramosetron.Ramosetron is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting. Synonyms: 4,5,6,7-tetrahydro-3H-benzimidazole-5-carboxylic acid; 4,5,6,7-tetrahydro-3H-benzimidazole-5-carboxylic acid. Grade: > 95 %. CAS No. 26751-24-6. Molecular formula: C8H10N2O2. Mole weight: 166.18. | |
| 5,6,7,8-Tetrahydronaphthalene-1-carboxylic Acid | (3S)-N-[[(1S)-1,2,3,4-Tetrahydro-1-naphthalenyl]methyl]-1-azabicyclo[2.2.2]octan-3-amine is an intermediate of Palonosetron. Palonosetron (INN, trade name Aloxi) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: 5,6,7,8-Tetrahydro-1-naphthalenecarboxylic Acid; 5,6,7,8-Tetrahydro-1-naphthoic Acid; 5,6,7,8-Tetrahydro-1-naphthalenecarboxylic Acid; 5,6,7,8-Tetrahydro-1-naphthoic Acid; 5,6,7,8-Tetrahydronaphthalen-1-carboxylic Acid; NSC 44874. Grade: ≥95%. CAS No. 4242-18-6. Molecular formula: C11H12O2. Mole weight: 176.21. | |
| 5,6-Dihydronaphthalene-1-carbonyl Chloride | 5,6-Dihydronaphthalene-1-carbonyl Chloride is an intermediate in the synthesis of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: 5,6-Dihydro-1-naphthalenecarbonyl chloride; 1-Naphthalenecarbonyl chloride, 5,6-dihydro-. Molecular formula: C11H9ClO. Mole weight: 192.64. | |
| 5,6-Dihydronaphthalene-1-carboxylic Acid | 5,6-Dihydronaphthalene-1-carboxylic Acid is an intermediate in the synthesis of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: 1-Naphthalenecarboxylic acid, 5,6-dihydro-; 5,6-Dihydro-1-naphthalenecarboxylic Acid. CAS No. 444914-74-3. Molecular formula: C11H10O2. Mole weight: 174.20. | |
| 6,7,8,8a-Tetrahydro-2H-naphtho[1,8-bc]furan-2-one | 6,7,8,8a-Tetrahydro-2H-naphtho[1,8-bc]furan-2-one is an intermediate in the synthesis of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: 2H-Naphtho[1,8-bc]furan-2-one, 6,7,8,8a-tetrahydro-. Grade: ≥95%. CAS No. 74145-12-3. Molecular formula: C11H10O2. Mole weight: 174.20. | |
| 6-Hydroxy ondansetron | An impurity of Ondansetron, which is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic. Synonyms: 1,2,3,9-Tetrahydro-6-hydroxy-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one. Grade: > 95%. CAS No. 110708-17-3. Molecular formula: C19H20N2O2. Mole weight: 311.39. | |
| 6-Hydroxy-(S,S)-Palonosetron | 6-Hydroxy-(S,S)-Palonosetron is a metabolite of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: (3aR)-2-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-6-hydroxy-1H-benz[de]isoquinolin-1-one; (3aR)-6-hydroxy-2-((S)-quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one; 1H-Benz[de]isoquinolin-1-one, 2-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-6-hydroxy-, (3aR)-. Molecular formula: C19H24N2O2. Mole weight: 312.41. | |
| 6-Oxo-(S,S)-Palonosetron | 6-Oxo-(S,S)-Palonosetron is an impurity of Palonosetron, which is a potent, single stereoisomeric 5-HT3 receptor antagonist developed to prevent chemotherapy-induced nausea and vomiting. Synonyms: 6-Oxo-(S,S)-Palonosetron (~90%); (S)-2-((S)-Quinuclidin-3-yl)-3,3a,4,5-tetrahydro-1H-benzo[de]isoquinoline-1,6(2H)-dione. Grade: 90%. CAS No. 848074-10-2. Molecular formula: C19H22N2O2. Mole weight: 310.39. | |
| (6R)-Hydroxy (R,S)-Palonosetron | (6R)-Hydroxy (R,S)-Palonosetron is a metabolite of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: [3aR-[2(S*),3aα,6α]]-2-(1-azabicyclo[2.2.2]oct-3-yl)-2,3,3a,4,5,6-hexahydro-6-hydroxy-1H-Benz[de]isoquinolin-1-one; Palonosetron Impurity 46; 1H-Benz[de]isoquinolin-1-one, 2-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-6-hydroxy-, (3aR,6R)-. Grade: ≥95%. CAS No. 175873-26-4. Molecular formula: C19H24N2O2. Mole weight: 312.41. | |
| (6R)-Hydroxy (S,S)-Palonosetron | (6R)-Hydroxy (S,S)-Palonosetron is a metabolite of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: [3aS-[2(S*),3aα,6α]]-2-(1-azabicyclo[2.2.2]oct-3-yl)-2,3,3a,4,5,6-hexahydro-6-hydroxy-1H-Benz[de]isoquinolin-1-one; 1H-Benz[de]isoquinolin-1-one, 2-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-6-hydroxy-, (3aS,6R)-; (3aS,6R)-2-[(3S)-1-Azabicyclo[2.2.2]oct-3-yl]-6-hydroxy-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one. Grade: ≥95%. CAS No. 176019-33-3. Molecular formula: C19H24N2O2. Mole weight: 312.41. | |
| (6S)-Hydroxy (R,S)-Palonosetron | (6S)-Hydroxy (R,S)-Palonosetron is a metabolite of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: (3aR,6S)-2-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-6-hydroxy-1H-benz[de]isoquinolin-1-one; (3aR,6S)-6-hydroxy-2-((S)-quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one; 1H-Benz[de]isoquinolin-1-one, 2-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-6-hydroxy-, (3aR,6S)-. Molecular formula: C19H24N2O2. Mole weight: 312.41. | |
| 7-Hydroxy Granisetron | 7-Hydroxy Granisetron is a potent and selective 5-hydroxytryptamine type 3 (5-HT3) receptor antagonist used in the research of chemotherapy-induced nausea and vomiting. Synonyms: 7-Hydroxy-1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide. Grade: > 95%. CAS No. 133841-15-3. Molecular formula: C18H24N4O2. Mole weight: 328.42. | |
| 7-Hydroxy Granisetron-d3 HCl | 7-Hydroxy Granisetron-d3 HCl is a labelled Granisetron metabolite. Granisetron is a serotonin 5-HT3 receptor antagonist used for the treatment of nausea and vomiting caused by chemotherapy. Synonyms: 7-Hydroxy-1-Methyl-N-[(3-endo)-9-Methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxaMide-d3 Hydrochloride. Grade: > 95%. Molecular formula: C18H22N4O2D3Cl. Mole weight: 367.90. | |
| 7-Hydroxy Granisetron Hydrochloride | 7-Hydroxy Granisetron Hydrochloride is a metabolite of Granisetron, a 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Synonyms: 7-Hydroxy-1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide Hydrochloride. Grade: 95%. CAS No. 133841-04-0. Molecular formula: C18H25ClN4O2. Mole weight: 364.87. | |
| 7-Hydroxy Ondansetron | An impurity of Ondansetron, which is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic. Synonyms: 1,2,3,9-Tetrahydro-7-hydroxy-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]- 4H-carbazol-4-one. Grade: > 95%. CAS No. 126702-17-8. Molecular formula: C19H20N2O2. Mole weight: 311.39. | |
| 8-Hydroxy Ondansetron | An impurity of Ondansetron, which is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic. Synonyms: 1,2,3,9-Tetrahydro-8-hydroxy-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one. Grade: > 95%. CAS No. 126671-71-4. Molecular formula: C18H19N3O2. Mole weight: 309.36. | |
| Alosetron | Alosetron, an effective 5-HT3 receptor antagonist, could be commonly used against irritable bowel syndrome. Uses: Alosetron is an effective 5-ht3 receptor antagonist and could be commonly used against irritable bowel syndrome. Synonyms: Alosetron, GR 68755, GR68755, GR-68755, Lotronex; ALOSETRON2,3,4,5-Tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one. Grade: 95%. CAS No. 122852-42-0. Molecular formula: C17H18N4O. Mole weight: 294.36. | |
| Alosetron-[d3] | Alosetron-[d3] is the labelled analogue of Alosetron, which is a 5-HT3 receptor antagonist used in the treatment of irritable bowel syndrome (IBS). Synonyms: Alosetron D3; 2,3,4,5-Tetrahydro-5-(methyl-d3)-2-[(4-methyl-1H-imidazol-5-yl)methyl]-1H-pyrido[4,3-b]indol-1-one; Lotronex-d3; 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4-dihydropyrido[4,3-b]indol-1-one-d3. Grade: 98% by HPLC. CAS No. 1190043-13-0. Molecular formula: C17H15D3N4O. Mole weight: 297.37. | |
| Alosetron-[d3] Hydrochloride | Alosetron-[d3] Hydrochloride is the labelled analogue of Alosetron Hydrochloride, which is a 5-HT3 receptor antagonist used in the treatment of irritable bowel syndrome (IBS). Uses: The hydrochloride salt form of isotope labelled alosetrone. Synonyms: Alosetron-d3 Hydrochloride; 2,3,4,5-Tetrahydro-5-(methyl-d3)-2-[(4-methyl-1H-imidazol-5-yl)methyl]-1H-pyrido[4,3-b]indol-1-one Hydrochloride; GR 68755-d3; GR 68755X-d3; Lotronex-d3 Hydrochloride. Grade: >95%. CAS No. 1189919-71-8. Molecular formula: C17H15D3N4O.HCl. Mole weight: 333.83. | |
| Alosetron HCl | The hydrochloride salt form of Alosetron which is an effective 5-HT3 receptor antagonist and could be commonly used against irritable bowel syndrome. Uses: The hydrochloride salt form of alosetron which is an effective 5-ht3 receptor antagonist and could be commonly used against irritable bowel syndrome. Synonyms: 2,3,4,5-Tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-1H-pyrido[4,3-b]indol-1-one Hydrochloride. Grade: > 95%. CAS No. 122852-69-1. Molecular formula: C17H18N4O. HCl. Mole weight: 330.81. | |
| Alosetron Hydrochloride | Alosetron Hydrochloride (GR 68755C) is a potent and highly selective serotonin 5-HT3 receptor antagonist. Alosetron Hydrochloride is used for the research of irritable bowel syndrome (IBS). Alosetron blocks the fast 5HT3-mediated depolarisation of guinea-pig myenteric and submucosal neurons, with IC 50 at ~55 nM. Alosetron Hydrochloride attenuates the visceral nociceptive effect of rectal distension in conscious or anaesthetised dogs. Anti-inflammatory effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GR 68755C; GR 68755 Hydrochloride; GR 68755X Hydrochloride. CAS No. 122852-69-1. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-70050C. | |
| Alosetron (Z)-2-butenedioate | The maleic acid salt form of Alosetron which is an effective 5-HT3 receptor antagonist and could be commonly used against irritable bowel syndrome. Uses: The maleic acid salt form of alosetron which is an effective 5-ht3 receptor antagonist and could be commonly used against irritable bowel syndrome. Synonyms: (Z)-but-2-enedioicacid; 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4-dihydropyrido[4,3-b]indol-1-one; Alosetron((Z)-2-butenedioate); 122852-43-1; SCHEMBL1045; Alosetron(Z)-2-butenedioate. Grade: 95%. CAS No. 122852-43-1. Molecular formula: C21H22N4O5. Mole weight: 410.42. | |
| Anpirtoline | Anpirtoline is a highly potent 5-HT1B receptor agonist with a Ki value of 28 nM. It decreases central serotonin synthesis and attenuates aggressive behavior in vivo. It also acts as an antagonist at 5-HT3 receptor with a Ki value of 29.5 nM and is brain penetrant. It is a receptor agonist with antinociceptive/antidepressant-like actions in rodents. Synonyms: Pyridine, 2-chloro-6-(4-piperidinylthio)-; 2-Chloro-6-(4-piperidinylthio)pyridine; 2-Chloro-6-(piperidin-4-ylsulfanyl)pyridine; 4-((6-Chloro-2-pyridyl)thio)piperidine; 6-chloro-2-(piperidyl-4-thiol)pyridine; 2-Chloro-6-(4-piperidinylsulfanyl)pyridine. Grade: ≥95%. CAS No. 98330-05-3. Molecular formula: C10H13ClN2S. Mole weight: 228.74. | |
| Anpirtoline hydrochloride | Anpirtoline hydrochloride is the hydrochloride salt of anpirtoline, which is a highly potent 5-HT1B receptor agonist with Ki values of 28 nM. It decreases central serotonin synthesis and attenuates aggressive behavior in vivo. It also acts as an antagonist at 5-HT3 receptors with Ki value of 29.5 nM and is brain penetrant. It is a receptor agonist with antinociceptive/antidepressant-like actions in rodents. Synonyms: Pyridine, 2-chloro-6-(4-piperidinylthio)-, hydrochloride (1:1); Pyridine, 2-chloro-6-(4-piperidinylthio)-, monohydrochloride; 2-Chloro-6-(piperidin-4-ylsulfanyl)pyridine hydrochloride; 2-Chloro-6-(piperidin-4-ylthio)pyridine hydrochloride; D16949; D-16949. D 16949. Grade: ≥99% by HPLC. CAS No. 99201-87-3. Molecular formula: C10H14Cl2N2S. Mole weight: 265.20. | |
| Azasetron-13C,D3 Hydrochloride | A 5-HT3 receptor antagonist. Used as an antiemetic. Group: Biochemicals. Alternative Names: N-1-Azabicyclo[2.2.2]-oct-3-yl-6-chloro-3,4-dihydro-4-(methyl-13C,d3)-3-oxo-2H-1,4-benzoxazine-8-carboxamide Hydrochloride. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Azasetron-[d3] Hydrochloride | Azasetron-[d3] Hydrochloride is the labelled analogue of Azasetron Hydrochloride, which is a 5-HT3 receptor antagonist and used as an antiemetic. Synonyms: Azasetron-d3 Hydrochloride; N-1-Azabicyclo[2.2.2]-oct-3-yl-6-chloro-3,4-dihydro-4-(methyl-d3)-3-oxo-2H-1,4-benzoxazine-8-carboxamide Hydrochloride; Serotone-d3; Nazasetron-d3; Y-25130-d3 hydrochloride; 6-chloro-4-methyl-3-oxo-N-(quinuclidin-3-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-8-carboxamide-d3 hydrochloride. Grade: 98%; ≥99% atom D. CAS No. 1216505-58-6. Molecular formula: C17H18D3Cl2N3O3. Mole weight: 389.29. | |
| Azasetron-d3, Hydrochloride (N-1-Azabicyclo[2.2.2]-oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-2H-1,4-benzoxazine-8-carboxamide-d3, Hydrochloride) | A 5-HT3 receptor antagonist. Used as an antiemetic. Group: Biochemicals. Alternative Names: N-1-Azabicyclo[2.2.2]-oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-2H-1,4-benzoxazine-8-carboxamide-d3, Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| (-)-Azasetron hydrochloride | The (-)-enantiomer of Azasetron hydrochloride, which is a selective 5-HT3 antagonist. Grade: 99%. CAS No. 123040-96-0. Molecular formula: C17H20ClN3O3.HCl. Mole weight: 386.27. | |
| (+)-Azasetron hydrochloride | The (+)-enantiomer of Azasetron hydrochloride, which is a selective 5-HT3 antagonist. Uses: Antiemetics. Synonyms: azasetron hydrochloride; 123040-16-4; Azasetron HCl; 123040-69-7; Serotone; Y-25130 hydrochloride; 141922-90-9; Azasetron (hydrochloride); AZASETRONHYDROCHLORIDE; Azasetron hydrochloride [JAN]; D-erythro-Sphingosine (Brain, Porcine); 123040-93-7; 477243-03-1; 123040-96-0; 2BSS7XL60S; 123040-94-8; Y-25130 HCl; 2H-1,4-Benzoxazine-8-carboxamide, N-1-azabicyclo[2.2.2]oct-3-yl-6-chloro-3,4-dihydro-4-me. Grade: 99%. CAS No. 123040-94-8. Molecular formula: C17H20ClN3O3.HCl. Mole weight: 386.27. | |
| Azasetron hydrochloride | Azasetron HCl is a selective 5-HT3 receptor antagonist with IC50 of 0.33 nM used in the management of nausea and vomiting induced by cancer chemotherapy. Uses: Antiemetics. Synonyms: Azasetron hydrochloride; Y 25130; Y-25130; Y25130. Y-25130 HCl. Grade: >98%. CAS No. 123040-16-4. Molecular formula: C17H20ClN3O3.HCl. Mole weight: 386.27. | |
| Azasetron hydrochloride | Azasetron (Y-25130) hydrochloride, a benzamide derivative, is a potent and selective 5-HT3 receptor antagonist. Azasetron is used in the study for Chemotherapy-induced nausea and vomiting (CINV) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Y-25130 hydrochloride. CAS No. 123040-16-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0068. | |
| Azasetron, Hydrochloride (N-1-Azabicyclo[2.2.2]-oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-2H-1,4-benzoxazine-8-carboxamide, Hydrochloride) | A 5-HT3 receptor antagonist. Used as an antiemetic. Group: Biochemicals. Alternative Names: N-1-Azabicyclo[2.2.2]-oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-2H-1,4-benzoxazine-8-carboxamide, Hydrochloride. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| beta-Tropisetron | Tropisetron, also known as ICS-205930, is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic to treat nausea and vomiting following chemotherapy, although it has been used experimentally as an analgesic in cases of fibromyalgia. Uses: Antiemetics. Synonyms: Navoban. ICS 205-930. (1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 1methyl-indole-3-carboxylate. Grade: >98%. CAS No. 89565-68-4. Molecular formula: C17H20N2O2. Mole weight: 284.35. | |
| Capecitabine | N(4)-Pentyloxycarbonyl-5'-deoxy-5-fluorocytidine; Pentyl N-[1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-methyl-oxolan-2-yl]-5-fluoro-2-oxo-pyrimidin-4-yl]carbamate. antinauseant and antiemetic highly specific and selective serotonin subtype 3 (5-HT3) receptor antagonist. CAS No. 158798-73-3. Product ID: 8-04318. Molecular formula: C15H22FN3O6. Mole weight: 359.35. Properties: mp 236-237°C. |  |
| Dalasetron Mesylate hydrate | Dalasetron Mesylate hydrate is a serotonin 5-HT3 receptor antagonist. It is used to treat nausea and vomiting following chemotherapy. Uses: Dalasetron mesylate hydrate is used to treat nausea and vomiting following chemotherapy. Synonyms: rel-(6R,9aS)-Octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl 1H-indole-3-carboxylate methanesulfonate hydrate. Grade: >98 %. CAS No. 878143-33-0. Molecular formula: C20H26N2O7S. Mole weight: 438.49. | |
| Des-4-fluorobenzyl Mosapride | Des-4-fluorobenzyl Mosapride is an impurity of Mosapride. Mosapride is a 5-HT4 receptor agonist and 5-HT3 receptor antagonist. It is used as a gastroprokinetic agent. Synonyms: Des-p-fluorobenzyl mosapride; Mosapride Impurity 5; 4-amino-5-chloro-2-ethoxy-N-((2-morpholinyl)methyl)benzamide. Grade: 95%. CAS No. 152013-26-8. Molecular formula: C14H20ClN3O3. Mole weight: 313.79. | |
| Des-5'-chloro-4-fluorobenzyl Mosapride | Des-5'-chloro-4-fluorobenzyl Mosapride is an intermediate of Mosapride, which is a selective agonist of 5-HT4 receptor, could be used as an astroprokinetic agent. It is also found to be a 5-HT3 receptor antagonist. Uses: Intermediate in the preparation of mosapride and its metabolites. Synonyms: 4-Amino-2-ethoxy-N-(2-morpholinylmethyl)benzamide; Benzamide, 4-amino-2-ethoxy-N-(2-morpholinylmethyl)-. Grade: 98%. CAS No. 170799-30-1. Molecular formula: C14H21N3O3. Mole weight: 279.33. | |
| Des-C-methyl ondansetron hydrochloride | An impurity of Ondansetron, which is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic. Synonyms: 3-((1H-Imidazol-1-yl)methyl)-9-methyl-1,2,3,9-tetrahydro-4H-carbazol-4-one hydrochloride; (3RS)-3-(1H-Imidazol-1-ylmethyl)-9-methyl-1,2,3,9-tetrahydro-4H-carbazol-4-one monohydrochloride. CAS No. 99614-04-7. Molecular formula: C17H18ClN3O. Mole weight: 315.80. | |
| Desoxy-Palonosetron Dihydrochloride | Desoxy-Palonosetron Dihydrochloride is a derivative of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: (S)-2-((S)-quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinoline dihydrochloride. Grade: ≥95%. Molecular formula: C19H28Cl2N2. Mole weight: 355.34. | |
| Desoxy-Palonosetron Dihydrochloride | Hydrochloride salt of Desoxy-Palonosetron is a derivative of Palonosetron (P165800) a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Dolasetron | Dolasetron, a pseudopelletierine derivative, is a 5-HT3 receptor antagonist that could be used to relieve the nausea and vomiting caused by chemotherapy. Synonyms: 1H-Indole-3-carboxylic acid, octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester, stereoisomer; 1H-Indole-3-carboxylic acid, octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester, (2α,6α,8α,9aβ)-; Anemet; MDL 73147. Grade: 95%. CAS No. 115956-12-2. Molecular formula: C19H20N2O3. Mole weight: 324.37. | |
| Dolasetron | Dolasetron(MDL-73147) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MDL-73147. CAS No. 115956-12-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B0750. | |
| Dolasetron mesylate | The mesylate salt form of Dolasetron which is a pseudopelletierine derivative and could be used to relieve the nausea and vomiting caused by chemotherapy for behaving as a 5-HT3 receptor antagonist. Synonyms: Dolasetron methanesulfonate; Dolasetron mesilate. Grade: 98%. CAS No. 115956-13-3. Molecular formula: C19H20N2O3.CH4O3S. Mole weight: 420.48. | |
| Dolasetron Mesylate hydrate | Dolasetron Mesylate hydrate (MDL-73147EF hydrate) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MDL-73147EF hydrate. CAS No. 878143-33-0. Pack Sizes: 100 mg; 200 mg. Product ID: HY-B0750B. | |
| Fabesetron | Fabesetron is an orally active 5-HT3 receptor antagonist with 5-HT4 receptor antagonistic activity. Fabesetron can be used in the study for both acute and delayed emesis induced by cancer chemotherapy. Synonyms: (+)-(R)-8,9-Dihydro-10-methyl-7-((5-methylimidazol-4-yl)methyl)pyrido(1,2-a)indol-6(7H)-one; Pyrido[1,2-a]indol-6(7H)-one, 8,9-dihydro-10-methyl-7-[(4-methyl-1H-imidazol-5-yl)methyl]-, (7R)-; FK1052; FK-1052. CAS No. 129300-27-2. Molecular formula: C18H19N3O. Mole weight: 293.36. | |
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