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| Product | Description | |
|---|---|---|
| 5-HT3 antagonist 5 | 5-HT3 antagonist 5 is a 5-HT3 receptor antagonist with anti-depressant activity. Synonyms: N-(4-methoxyphenyl)-2-quinoxalinecarboxamide. CAS No. 901599-43-7. Molecular formula: C16H13N3O2. Mole weight: 279.29. |  |
| 5-HT3 antagonist 5 | 5-HT3 antagonist 5 is a quinoxalin-2-carboxamide compound, a 5-HT 3 receptor antagonist. 5-HT3 antagonist 5 exerts antagonism on 5-HT 3 agonist and 2-methyl-5-HT , and shows anti-depressant effect in mice [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 901599-43-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148038. |  |
| 5-HT3 antagonist 1 | A potent and selective antagonist of serotonin 3 (5-HT3) receptor. Synonyms: 1H-1,4-Diazepine, 1H-indazole-3-carboxamide deriv. CAS No. 129294-09-3. Molecular formula: C22H27N5O. Mole weight: 377.48. | |
| 1, 2, 3, 3', 4, 4'-Hexahydro-[1, 1'-binaphthalene]-8, 8'-dicarboxylic Acid | 1, 2, 3, 3', 4, 4'-Hexahydro-[1, 1'-binaphthalene]-8, 8'-dicarboxylic Acid is an impurity of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Molecular formula: C22H20O4. Mole weight: 348.40. | |
| 1,4-Dimethyl-2,6-piperazinediacetic Acid Dimethyl Ester | 1,4-Dimethyl-2,6-piperazinediacetic Acid Dimethyl Ester is an intermediate in the synthesis of Indisetron (I532500), which is a 5-HT3 receptor antagonist as an antiemetic agent. It is used for treatment of digestive tract disorders. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C12H22N2O4. US Biological Life Sciences. |  Worldwide |
| 1-Methylindole | An impurity of Ramosetron.Ramosetron is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting. Synonyms: 1-methylindole. Grades: > 95 %. CAS No. 603-76-9. Molecular formula: C9H9N. Mole weight: 131.17. | |
| 1-Methylindole-3-carboxylic acid | An impurity of Ramosetron.Ramosetron is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting. Synonyms: 1-methylindole-3-carboxylic acid. Grades: > 95 %. CAS No. 32387-21-6. Molecular formula: C10H9NO2. Mole weight: 175.18. | |
| 1-Methylisatin | An impurity of Ramosetron.Ramosetron is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting. Synonyms: 1-methylindole-2,3-dione. Grades: > 95 %. CAS No. 2058-74-4. Molecular formula: C9H7NO2. Mole weight: 161.16. | |
| (1S)-N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-1,2,3,4-tetrahydro-1-naphthalenecarboxamide | (1S)-N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-1,2,3,4-tetrahydro-1-naphthalenecarboxamide is an intermediate of Palonosetron. Palonosetron (INN, trade name Aloxi) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: (S)-N-((R)-quinuclidin-3-yl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide; 1-Naphthalenecarboxamide, N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-1,2,3,4-tetrahydro-, (1S)-. Molecular formula: C18H24N2O. Mole weight: 284.40. | |
| (1S)-N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-1,2,3,4-tetrahydro-1-naphthalenecarboxamide | (1S)-N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-1,2,3,4-tetrahydro-1-naphthalenecarboxamide is an intermediate of Palonosetron. Palonosetron (INN, trade name Aloxi) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Uses: Palonosetron intermediate. Synonyms: [S-(R*,R*)]-N-1-Azabicyclo[2.2.2]oct-3-yl-1,2,3,4-tetrahydro-1-naphthalenecarboxamide; (S)-N-((S)-quinuclidin-3-yl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide; 1-Naphthalenecarboxamide, N-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-1,2,3,4-tetrahydro-, (1S)-; Palonosetron Impurity 4. Grades: ≥95%. CAS No. 177793-79-2. Molecular formula: C18H24N2O. Mole weight: 284.40. | |
| 2- [1- (4-Piperonyl) piperazinyl] benzothiazole | 5-HT4 receptor agonist with moderate activity as a 5-HT3 antagonist. Has no affinity at 5-HT1 or dopamine D2 receptors. Potential gastrokinetic agent. Group: Biochemicals. Grades: Purified. CAS No. 155106-73-3. Pack Sizes: 10mg, 50mg. Molecular Formula: C19H19N3O2S. US Biological Life Sciences. | Worldwide |
| 2-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-2,4,5,6-tetrahydro-1H-benz[de]isoquinolin-1-one Hydrochloride | 2-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-2,4,5,6-tetrahydro-1H-benz[de]isoquinolin-1-one Hydrochloride is an intermediate in the synthesis of Palonosteron (P165805), an serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting. Group: Biochemicals. Grades: Highly Purified. CAS No. 135729-66-7. Pack Sizes: 5mg, 10mg. Molecular Formula: C19H23ClN2O. US Biological Life Sciences. | Worldwide |
| 2-Aminomethyl-4-(4-fluorobenzyl)morpholine | 2-Aminomethyl-4-(4-fluorobenzyl)morpholine is an intermediate of Mosapride, which is a selective agonist of 5-HT4 receptor, could be used as an astroprokinetic agent. It is also found to be a 5-HT3 receptor antagonist. Uses: Mosapride intermediate. Synonyms: 4-[(4-Fluorophenyl)methyl]-2-morpholinemethanamine; 1-[4-(4-Fluorobenzyl)-2-morpholinyl]methanamine; 1-[4-(4-Fluorobenzyl)morpholin-2-yl]methanamine; 2-Morpholinemethanamine, 4-[(4-fluorophenyl)methyl]-. Grades: ≥95%. CAS No. 112914-13-3. Molecular formula: C12H17FN2O. Mole weight: 224.27. | |
| (2E,2'E)-4,4'-(Methylimino)bis-2-butenoic Acid Dimethyl Ester | (2E,2'E)-4,4'-(Methylimino)bis-2-butenoic Acid Dimethyl Ester is an intermediate in the synthesis of Indisetron (I532500), which is a 5-HT3 receptor antagonist as an antiemetic agent. It is used for treatment of digestive tract disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 852052-29-0. Pack Sizes: 50mg, 100mg. Molecular Formula: C11H17NO4. US Biological Life Sciences. | Worldwide |
| 2-((S)-Quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinoline | 2-((S)-Quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinoline is an intermediate in the synthesis of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: 2-[(3S)-1-Azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinoline; 1H-Benz[de]isoquinoline, 2-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-; Palonosetron Impurity 15. Grades: ≥95%. CAS No. 1796933-62-4. Molecular formula: C19H26N2. Mole weight: 282.42. | |
| 3a,4,5,6-Tetrahydro-1H,3H-naphtho[1,8-cd]pyran-1-one | 3a,4,5,6-Tetrahydro-1H,3H-naphtho[1,8-cd]pyran-1-one is an intermediate in the synthesis of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: 3a,4,5,6-tetrahydro-1H,3H-benzo[de]isochromen-1-one; 1H,3H-Naphtho[1,8-cd]pyran-1-one, 3a,4,5,6-tetrahydro-; Palonosetron Impurity 55. CAS No. 81603-30-7. Molecular formula: C12H12O2. Mole weight: 188.22. | |
| 3-Aminomethyl-4-(4-fluorobenzyl)morpholine | 3-Aminomethyl-4-(4-fluorobenzyl)morpholine is an impurity of Mosapride, which is a selective agonist of 5-HT4 receptor, could be used as an astroprokinetic agent. It is also found to be a 5-HT3 receptor antagonist. Uses: Mosapride (a616180) impurity. Synonyms: 4-[(4-Fluorophenyl)methyl]-3-morpholinemethanamine. Grades: ≥95%. CAS No. 174561-70-7. Molecular formula: C12H17FN2O. Mole weight: 224.27. | |
| 3-AQC | 3-AQC has been found to be a competitive 5-HT3 antagonist with widely differing activity in various tissues. Synonyms: 2-Quinoxalinecarbonitrile, 3-[4-(2-propen-1-yl)-1-piperazinyl]-, (2Z)-2-butenedioate (1:1); 3 AQC; 3AQC; 3-(4-Allylpiperazin-1-yl)-2-quinoxalinecarbonitrile maleate; 2-Quinoxalinecarbonitrile, 3-[4-(2-propenyl)-1-piperazinyl]-, (2Z)-2-butenedioate (1:1); 2-Quinoxalinecarbonitrile, 3-[4-(2-propenyl)-1-piperazinyl]-, (Z)-2-butenedioate (1:1); 3-(4-allylpiperazin-1-yl)quinoxaline-2-carbonitrile maleate. Grades: ≥95% by HPLC. CAS No. 201216-42-4. Molecular formula: C16H17N5.C4H4O4. Mole weight: 395.42. | |
| 3-Bromo-7-methoxy-1H-indazole | 3-Bromo-7-methoxy-1H-indazole is an intermediate in the synthesis of 7-Hydroxy Granisetron (H942675), a metabolite of Granisetron (G780000), a specific serotonin (5HT3) receptor antagonist. Used as an antiemetic. Granisetron HCl is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptor. Group: Biochemicals. Grades: Highly Purified. CAS No. 133841-06-2. Pack Sizes: 250mg, 2.5g. Molecular Formula: C8H7BrN2O, Molecular Weight: 227.06. US Biological Life Sciences. | Worldwide |
| (3S)-Aminoquinuclidine Dihydrochloride | (3S)-Aminoquinuclidine Dihydrochloride is an intermediate in the synthesis of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Uses: Palonosetron intermediate. Synonyms: (S)-quinuclidin-3-amine dihydrochloride; (3S)-1-Azabicyclo[2.2.2]octan-3-amine Hydrochloride (1:2); (3S)-3-Amino-1-azabicyclo[2.2.2]octane Dihydrochloride; (3S)-quinuclidin-3-amine Dihydrochloride; 1-Azabicyclo[2.2.2]octan-3-amine, (3S)-, hydrochloride (1:2). Grades: ≥95%. CAS No. 119904-90-4. Molecular formula: C7H16Cl2N2. Mole weight: 199.12. | |
| (3S)-N-[[(1S)-1,2,3,4-Tetrahydro-1-naphthalenyl]methyl]-1-azabicyclo[2.2.2]octan-3-amine | (3S)-N-[[(1S)-1,2,3,4-Tetrahydro-1-naphthalenyl]methyl]-1-azabicyclo[2.2.2]octan-3-amine is an intermediate of Palonosetron. Palonosetron (INN, trade name Aloxi) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Uses: Palonosetron intermediate. Synonyms: [S-(R*,R*)]-N-[(1,2,3,4-Tetrahydro-1-naphthalenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine; (S)-N-(((S)-1,2,3,4-tetrahydronaphthalen-1-yl)methyl)quinuclidin-3-amine; Palonosetron Impurity 5. Grades: ≥95%. CAS No. 177793-80-5. Molecular formula: C18H26N2. Mole weight: 270.41. | |
| 4,5,6,7-Tetrahydro-1H-benzoimidazole-5-carboxylic Acid | An impurity of Ramosetron.Ramosetron is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting. Synonyms: 4,5,6,7-tetrahydro-3H-benzimidazole-5-carboxylic acid; 4,5,6,7-tetrahydro-3H-benzimidazole-5-carboxylic acid. Grades: > 95 %. CAS No. 26751-24-6. Molecular formula: C8H10N2O2. Mole weight: 166.18. | |
| 5,6,7,8-Tetrahydronaphthalene-1-carboxylic Acid | (3S)-N-[[(1S)-1,2,3,4-Tetrahydro-1-naphthalenyl]methyl]-1-azabicyclo[2.2.2]octan-3-amine is an intermediate of Palonosetron. Palonosetron (INN, trade name Aloxi) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: 5,6,7,8-Tetrahydro-1-naphthalenecarboxylic Acid; 5,6,7,8-Tetrahydro-1-naphthoic Acid; 5,6,7,8-Tetrahydro-1-naphthalenecarboxylic Acid; 5,6,7,8-Tetrahydro-1-naphthoic Acid; 5,6,7,8-Tetrahydronaphthalen-1-carboxylic Acid; NSC 44874. Grades: ≥95%. CAS No. 4242-18-6. Molecular formula: C11H12O2. Mole weight: 176.21. | |
| 5,6-Dihydronaphthalene-1-carbonyl Chloride | 5,6-Dihydronaphthalene-1-carbonyl Chloride is an intermediate in the synthesis of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: 5,6-Dihydro-1-naphthalenecarbonyl chloride; 1-Naphthalenecarbonyl chloride, 5,6-dihydro-. Molecular formula: C11H9ClO. Mole weight: 192.64. | |
| 5,6-Dihydronaphthalene-1-carboxylic Acid | 5,6-Dihydronaphthalene-1-carboxylic Acid is an intermediate in the synthesis of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: 1-Naphthalenecarboxylic acid, 5,6-dihydro-; 5,6-Dihydro-1-naphthalenecarboxylic Acid. CAS No. 444914-74-3. Molecular formula: C11H10O2. Mole weight: 174.20. | |
| 6,7,8,8a-Tetrahydro-2H-naphtho[1,8-bc]furan-2-one | 6,7,8,8a-Tetrahydro-2H-naphtho[1,8-bc]furan-2-one is an intermediate in the synthesis of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: 2H-Naphtho[1,8-bc]furan-2-one, 6,7,8,8a-tetrahydro-. Grades: ≥95%. CAS No. 74145-12-3. Molecular formula: C11H10O2. Mole weight: 174.20. | |
| 6-Hydroxy ondansetron | An impurity of Ondansetron, which is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic. Synonyms: 1,2,3,9-Tetrahydro-6-hydroxy-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one. Grades: > 95%. CAS No. 110708-17-3. Molecular formula: C19H20N2O2. Mole weight: 311.39. | |
| 6-Hydroxy-(S,S)-Palonosetron | 6-Hydroxy-(S,S)-Palonosetron is a metabolite of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: (3aR)-2-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-6-hydroxy-1H-benz[de]isoquinolin-1-one; (3aR)-6-hydroxy-2-((S)-quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one; 1H-Benz[de]isoquinolin-1-one, 2-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-6-hydroxy-, (3aR)-. Molecular formula: C19H24N2O2. Mole weight: 312.41. | |
| 6-Oxo-(S,S)-Palonosetron | 6-Oxo-(S,S)-Palonosetron is an impurity of Palonosetron, which is a potent, single stereoisomeric 5-HT3 receptor antagonist developed to prevent chemotherapy-induced nausea and vomiting. Synonyms: 6-Oxo-(S,S)-Palonosetron (~90%); (S)-2-((S)-Quinuclidin-3-yl)-3,3a,4,5-tetrahydro-1H-benzo[de]isoquinoline-1,6(2H)-dione. Grades: 90%. CAS No. 848074-10-2. Molecular formula: C19H22N2O2. Mole weight: 310.39. | |
| (6R)-Hydroxy (R,S)-Palonosetron | (6R)-Hydroxy (R,S)-Palonosetron is a metabolite of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: [3aR-[2(S*),3aα,6α]]-2-(1-azabicyclo[2.2.2]oct-3-yl)-2,3,3a,4,5,6-hexahydro-6-hydroxy-1H-Benz[de]isoquinolin-1-one; Palonosetron Impurity 46; 1H-Benz[de]isoquinolin-1-one, 2-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-6-hydroxy-, (3aR,6R)-. Grades: ≥95%. CAS No. 175873-26-4. Molecular formula: C19H24N2O2. Mole weight: 312.41. | |
| (6R)-Hydroxy (S,S)-Palonosetron | (6R)-Hydroxy (S,S)-Palonosetron is a metabolite of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: [3aS-[2(S*),3aα,6α]]-2-(1-azabicyclo[2.2.2]oct-3-yl)-2,3,3a,4,5,6-hexahydro-6-hydroxy-1H-Benz[de]isoquinolin-1-one; 1H-Benz[de]isoquinolin-1-one, 2-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-6-hydroxy-, (3aS,6R)-; (3aS,6R)-2-[(3S)-1-Azabicyclo[2.2.2]oct-3-yl]-6-hydroxy-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one. Grades: ≥95%. CAS No. 176019-33-3. Molecular formula: C19H24N2O2. Mole weight: 312.41. | |
| (6S)-Hydroxy (R,S)-Palonosetron | (6S)-Hydroxy (R,S)-Palonosetron is a metabolite of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: (3aR,6S)-2-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-6-hydroxy-1H-benz[de]isoquinolin-1-one; (3aR,6S)-6-hydroxy-2-((S)-quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one; 1H-Benz[de]isoquinolin-1-one, 2-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-6-hydroxy-, (3aR,6S)-. Molecular formula: C19H24N2O2. Mole weight: 312.41. | |
| 7-Hydroxy Ondansetron | An impurity of Ondansetron, which is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic. Synonyms: 1,2,3,9-Tetrahydro-7-hydroxy-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]- 4H-carbazol-4-one. Grades: > 95%. CAS No. 126702-17-8. Molecular formula: C19H20N2O2. Mole weight: 311.39. | |
| 8-Hydroxy Ondansetron | An impurity of Ondansetron, which is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic. Synonyms: 1,2,3,9-Tetrahydro-8-hydroxy-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one. Grades: > 95%. CAS No. 126671-71-4. Molecular formula: C19H20N2O2. Mole weight: 311.39. | |
| Alosetron | Alosetron, an effective 5-HT3 receptor antagonist, could be commonly used against irritable bowel syndrome. Uses: Alosetron is an effective 5-ht3 receptor antagonist and could be commonly used against irritable bowel syndrome. Synonyms: Alosetron, GR 68755, GR68755, GR-68755, Lotronex;ALOSETRON2,3,4,5-Tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one. Grades: 95%. CAS No. 122852-42-0. Molecular formula: C17H18N4O. Mole weight: 294.36. | |
| Alosetron HCl | The hydrochloride salt form of Alosetron which is an effective 5-HT3 receptor antagonist and could be commonly used against irritable bowel syndrome. Uses: The hydrochloride salt form of alosetron which is an effective 5-ht3 receptor antagonist and could be commonly used against irritable bowel syndrome. Synonyms: 2,3,4,5-Tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-1H-pyrido[4,3-b]indol-1-one Hydrochloride. Grades: > 95%. CAS No. 122852-69-1. Molecular formula: C17H18N4O. HCl. Mole weight: 330.81. | |
| Alosetron Hydrochloride | Alosetron Hydrochloride (GR 68755C) is a potent and highly selective serotonin 5-HT3 receptor antagonist. Alosetron Hydrochloride is used for the research of irritable bowel syndrome (IBS). Alosetron blocks the fast 5HT3-mediated depolarisation of guinea-pig myenteric and submucosal neurons, with IC 50 at ~55 nM. Alosetron Hydrochloride attenuates the visceral nociceptive effect of rectal distension in conscious or anaesthetised dogs. Anti-inflammatory effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GR 68755C; GR 68755 Hydrochloride; GR 68755X Hydrochloride. CAS No. 122852-69-1. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-70050C. | |
| Alosetron (Z)-2-butenedioate | The maleic acid salt form of Alosetron which is an effective 5-HT3 receptor antagonist and could be commonly used against irritable bowel syndrome. Uses: The maleic acid salt form of alosetron which is an effective 5-ht3 receptor antagonist and could be commonly used against irritable bowel syndrome. Synonyms: (Z)-but-2-enedioicacid;5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4-dihydropyrido[4,3-b]indol-1-one;Alosetron((Z)-2-butenedioate);122852-43-1;SCHEMBL1045;Alosetron(Z)-2-butenedioate. Grades: 95%. CAS No. 122852-43-1. Molecular formula: C21H22N4O5. Mole weight: 410.42. | |
| Anpirtoline hydrochloride | Anpirtoline hydrochloride is the hydrochloride salt of anpirtoline, which is a highly potent 5-HT1B receptor agonist with Ki values of 28 nM. It decreases central serotonin synthesis and attenuates aggressive behavior in vivo. It also acts as an antagonist at 5-HT3 receptors with Ki value of 29.5 nM and is brain penetrant. It is a receptor agonist with antinociceptive/antidepressant-like actions in rodents. Synonyms: Pyridine, 2-chloro-6-(4-piperidinylthio)-, hydrochloride (1:1); Pyridine, 2-chloro-6-(4-piperidinylthio)-, monohydrochloride; 2-Chloro-6-(piperidin-4-ylsulfanyl)pyridine hydrochloride; 2-Chloro-6-(piperidin-4-ylthio)pyridine hydrochloride; D16949; D-16949; D 16949. Grades: ≥99% by HPLC. CAS No. 99201-87-3. Molecular formula: C10H14Cl2N2S. Mole weight: 265.20. | |
| Azasetron-13C,D3 Hydrochloride | A 5-HT3 receptor antagonist. Used as an antiemetic. Group: Biochemicals. Alternative Names: N-1-Azabicyclo[2.2.2]-oct-3-yl-6-chloro-3,4-dihydro-4-(methyl-13C,d3)-3-oxo-2H-1,4-benzoxazine-8-carboxamide Hydrochloride. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Azasetron-d3, Hydrochloride (N-1-Azabicyclo[2.2.2]-oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-2H-1,4-benzoxazine-8-carboxamide-d3, Hydrochloride) | A 5-HT3 receptor antagonist. Used as an antiemetic. Group: Biochemicals. Alternative Names: N-1-Azabicyclo[2.2.2]-oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-2H-1,4-benzoxazine-8-carboxamide-d3, Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| (-)-Azasetron hydrochloride | The (-)-enantiomer of Azasetron hydrochloride, which is a selective 5-HT3 antagonist. Grades: 99%. CAS No. 123040-96-0. Molecular formula: C17H20ClN3O3.HCl. Mole weight: 386.27. | |
| (+)-Azasetron hydrochloride | The (+)-enantiomer of Azasetron hydrochloride, which is a selective 5-HT3 antagonist. Uses: Antiemetics. Synonyms: azasetron hydrochloride; 123040-16-4; Azasetron HCl; 123040-69-7; Serotone; Y-25130 hydrochloride; 141922-90-9; Azasetron (hydrochloride); AZASETRONHYDROCHLORIDE; Azasetron hydrochloride [JAN]; D-erythro-Sphingosine (Brain, Porcine); 123040-93-7; 477243-03-1; 123040-96-0; 2BSS7XL60S; 123040-94-8; Y-25130 HCl; 2H-1,4-Benzoxazine-8-carboxamide, N-1-azabicyclo[2.2.2]oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-, hydrochloride (1:1); N-(1-azabicyclo[2.2.2]octan-3-yl)-6-chloro-4-methyl-3-oxo-1,4-benzoxazine-8-carboxamide; hydrochloride; 6-chloro-4-methyl-3-oxo-N-(quinuclidin-3-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-8-carboxamide hydrochloride; Azasetron hydrochloride (JAN); Y-25130; 2H-1,4-Benzoxazine-8-carboxamide,N-1-azabicyclo[2.2.2]oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-,monohydrochloride, (+)-; 2H-1,4-Benzoxazine-8-carboxamide,N-1-azabicyclo[2.2.2]oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-,monohydrochloride,n. Grades: 99%. CAS No. 123040-94-8. Molecular formula: C17H20ClN3O3.HCl. Mole weight: 386.27. | |
| Azasetron hydrochloride | Azasetron HCl is a selective 5-HT3 receptor antagonist with IC50 of 0.33 nM used in the management of nausea and vomiting induced by cancer chemotherapy. Uses: Antiemetics. Synonyms: Azasetron hydrochloride;Y 25130; Y-25130; Y25130. Y-25130 HCl. Grades: >98%. CAS No. 123040-16-4. Molecular formula: C17H20ClN3O3.HCl. Mole weight: 386.27. | |
| Azasetron hydrochloride | Azasetron (Y-25130) hydrochloride, a benzamide derivative, is a potent and selective 5-HT3 receptor antagonist. Azasetron is used in the study for Chemotherapy-induced nausea and vomiting (CINV) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Y-25130 hydrochloride. CAS No. 123040-16-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0068. | |
| Azasetron, Hydrochloride (N-1-Azabicyclo[2.2.2]-oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-2H-1,4-benzoxazine-8-carboxamide, Hydrochloride) | A 5-HT3 receptor antagonist. Used as an antiemetic. Group: Biochemicals. Alternative Names: N-1-Azabicyclo[2.2.2]-oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-2H-1,4-benzoxazine-8-carboxamide, Hydrochloride. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| beta-Tropisetron | Tropisetron, also known as ICS-205930, is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic to treat nausea and vomiting following chemotherapy, although it has been used experimentally as an analgesic in cases of fibromyalgia. Uses: Antiemetics. Synonyms: Navoban. ICS 205-930. (1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 1methyl-indole-3-carboxylate. Grades: >98%. CAS No. 89565-68-4. Molecular formula: C17H20N2O2. Mole weight: 284.35. | |
| Capecitabine | N(4)-Pentyloxycarbonyl-5'-deoxy-5-fluorocytidine; Pentyl N-[1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-methyl-oxolan-2-yl]-5-fluoro-2-oxo-pyrimidin-4-yl]carbamate. antinauseant and antiemetic highly specific and selective serotonin subtype 3 (5-HT3) receptor antagonist. CAS No. 158798-73-3. Product ID: 8-04318. Molecular formula: C15H22FN3O6. Mole weight: 359.35. Properties: mp 236-237°C. |  |
| Clozapine hydrochloride | Clozapine (HF 1854) is an antipsychotic used to treat schizophrenia. Clozapine is a potent antagonist of dopamine and a number of other receptors. Clozapine is also a potent and selective agonist at the muscarinic M4 receptor. Clozapine is a partial agonist of the serotonin (5-HT) receptor subtype 5-HT1A. It also binds to the 5-HT2A, 5-HT2C, 5-HT3, 5-HT6, and 5-HT7 receptors, as well as the histamine H1 and α1-adrenergic receptors. Synonyms: 8-chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine dihydrochloride; HF 1854 dihydrochloride. Grades: ≥98%. Molecular formula: C18H19ClN4·2HCl. Mole weight: 399.74. | |
| Dalasetron Mesylate hydrate | Dalasetron Mesylate hydrate is a serotonin 5-HT3 receptor antagonist. It is used to treat nausea and vomiting following chemotherapy. Uses: Dalasetron mesylate hydrate is used to treat nausea and vomiting following chemotherapy. Synonyms: rel-(6R,9aS)-Octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl 1H-indole-3-carboxylate methanesulfonate hydrate. Grades: >98 %. CAS No. 878143-33-0. Molecular formula: C20H26N2O7S. Mole weight: 438.49. | |
| Des-5'-chloro-4-fluorobenzyl Mosapride | Des-5'-chloro-4-fluorobenzyl Mosapride is an intermediate of Mosapride, which is a selective agonist of 5-HT4 receptor, could be used as an astroprokinetic agent. It is also found to be a 5-HT3 receptor antagonist. Uses: Intermediate in the preparation of mosapride and its metabolites. Synonyms: 4-Amino-2-ethoxy-N-(2-morpholinylmethyl)benzamide; Benzamide, 4-amino-2-ethoxy-N-(2-morpholinylmethyl)-. Grades: 98%. CAS No. 170799-30-1. Molecular formula: C14H21N3O3. Mole weight: 279.33. | |
| Desoxy-Palonosetron Dihydrochloride | Desoxy-Palonosetron Dihydrochloride is a derivative of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: (S)-2-((S)-quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinoline dihydrochloride. Grades: ≥95%. Molecular formula: C19H28Cl2N2. Mole weight: 355.34. | |
| Desoxy-Palonosetron Dihydrochloride | Hydrochloride salt of Desoxy-Palonosetron is a derivative of Palonosetron (P165800) a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Dolasetron | Dolasetron, a pseudopelletierine derivative, is a 5-HT3 receptor antagonist that could be used to relieve the nausea and vomiting caused by chemotherapy. Synonyms: 1H-Indole-3-carboxylic acid, octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester, stereoisomer; 1H-Indole-3-carboxylic acid, octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester, (2α, 6α, 8α, 9aβ)-; Anemet; MDL 73147. Grades: 95%. CAS No. 115956-12-2. Molecular formula: C19H20N2O3. Mole weight: 324.37. | |
| Dolasetron | Dolasetron(MDL-73147) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MDL-73147. CAS No. 115956-12-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B0750. | |
| Dolasetron mesylate | The mesylate salt form of Dolasetron which is a pseudopelletierine derivative and could be used to relieve the nausea and vomiting caused by chemotherapy for behaving as a 5-HT3 receptor antagonist. Synonyms: Dolasetron methanesulfonate; Dolasetron mesilate. Grades: 98%. CAS No. 115956-13-3. Molecular formula: C19H20N2O3.CH4O3S. Mole weight: 420.48. | |
| Dolasetron Mesylate hydrate | Dolasetron Mesylate hydrate (MDL-73147EF hydrate) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MDL-73147EF hydrate. CAS No. 878143-33-0. Pack Sizes: 100 mg; 200 mg. Product ID: HY-B0750B. | |
| GR 113808 | GR 113808 is a potent and selective 5-HT4 receptor antagonist (pKB = 9.43 in human colonic muscle, Kd=0.15 nM for binding to cloned human 5-HT4 receptors). GR 113808 displays > 300-fold selectivity for 5-HT4 over 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2C and 5-HT3 receptors. Uses: Serotonin antagonists. Synonyms: GR 113808; GR113808; GR-113808. 1-methyl-1H-indole-3-carboxylic acid, [1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl]methyl ester. Grades: ≥98% by HPLC. CAS No. 144625-51-4. Molecular formula: C19H27N3O4S. Mole weight: 393.5. | |
| Granisetron | Granisetron (BRL 43694) is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BRL 43694. CAS No. 109889-09-0. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B0071. | |
| Granisetron | Granisetron is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medull. Uses: Granisetron is an antagonist of serptpmom 5-ht3 receptor and could be used to relieve the nausea and vomiting symptom after receving chemotherapy by decreasing the activity of the vagus nerve. Synonyms: 1-methyl-n-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-indazole-3-carboxamide; 1H-Indazole-3-carboxamide, 1-methyl-N-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-, endo-; BRL 43694. Grades: > 95%. CAS No. 109889-09-0. Molecular formula: C18H24N4O. Mole weight: 312.42. | |
| Granisetron hydroChloride | Granisetron HCl is a serotonin 5-HT3 receptor antagonist. Grades: >98%. CAS No. 107007-99-8. Molecular formula: C18H24N4O.HCl. Mole weight: 348.87. | |
| Granisetron Hydrochloride | Granisetron (Hydrochloride) (BRL 43694A) is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BRL 43694A. CAS No. 107007-99-8. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B0071A. | |
| GTS-21 dihydrochloride | GTS-21 dihydrochloride is a selective alpha7 nicotinic acetylcholine receptor (α7-nAChR) agonist with anti - inflammatory and cognition - enhancing activities. GTS-21 dihydrochloride is also a α4β2 ( K i =20 nM for humanα4β2) and 5-HT3A receptor ( IC 50 =3.1 μM) antagonist [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DMXB-A; DMBX-anabaseine. CAS No. 156223-05-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14564A. | |
| Lerisetron | Lerisetron is a serotonin type 3 (5-HT3) receptor antagonist with antiemetic activity. Lerisetron specifically binds to 5-HT3 receptors, located peripherally on vagus nerve terminals and centrally in the chemoreceptor trigger zone (CTZ) of the area postrema, which may result in suppression of chemotherapy-induced nausea and vomiting. Synonyms: 1-Benzyl-2-(piperazin-1-yl)-1H-benzo[d]imidazole; 1-benzyl-2-(piperazin-1-yl)-1H-benzimidazole. CAS No. 143257-98-1. Molecular formula: C18H20N4. Mole weight: 292.39. | |
| LY 278584 | LY 278584 is a 5-HT3-receptor antagonist and no detailed information has been published yet. Synonyms: LY 278584; LY-278584; LY278584. 1-methyl-N-[(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl]indazole-3-carboxamide. Grades: 98%. CAS No. 119193-37-2. Molecular formula: C17H22N4O. Mole weight: 298.39. | |
| MDL 72222 | MDL 72222 is a 5-HT3 receptor antagonist. Synonyms: MDL72222; MDL 72222; MDL-72222; Tropanyl 3,5-dichlorobenzoate; Bemesetron; endo-3,5-Dichloro-benzoic Acid 8-Methyl-8-azabicyclo[3.2.1]oct-3-yl Ester. Grades: ≥99% by HPLC. CAS No. 40796-97-2. Molecular formula: C15H17Cl2NO2. Mole weight: 314.21. | |
| Methyl 4-Acetamido-2-hydroxybenzoate | Methyl 4-Acetamido-2-hydroxybenzoate is a reagent used in the synthesis of Mosapride, which is a 5-HT4 receptor agonist and 5-HT3 receptor antagonist used as a gastroprokinetic agent. Synonyms: 4-(Acetylamino)-2-hydroxy-benzoic Acid Methyl Ester; 4-Acetylaminosalicylic Acid Methyl Ester; Methyl 2-Hydroxy-4-(acetylamino)benzoate; Methyl 4-(Acetylamino)salicylate; Methyl 4-Acetamidosalicylate; USP Ethopabate Related Compound A. Grades: ≥95%. CAS No. 4093-28-1. Molecular formula: C10H11NO4. Mole weight: 209.20. | |
| Methyl 5,6,7,8-tetrahydronaphthalene-1-carboxylate | Methyl 5,6,7,8-tetrahydronaphthalene-1-carboxylate is used in the preparation of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: 1-Naphthalenecarboxylic acid, 5,6,7,8-tetrahydro-, Methyl ester; Methyl tetralin-5-carboxylate; Methyl 5,6,7,8-tetrahydro-1-naphthalenecarboxylate; Methyl 1,2,3,4-tetrahydro-5-naphthalenecarboxylate; 5,6,7,8-tetrahydro-[1]naphthoic acid methyl ester. Grades: ≥95%. CAS No. 66193-59-7. Molecular formula: C12H14O2. Mole weight: 190.24. | |
| Mirisetron maleate | Mirisetron maleate, an oxoquinoline derivative, has been found to be a 5-HT3 receptor antagonist that could probably be effective against anxiety disorders and sleep disorders. It has been already discontinued by Wyeth. Synonyms: MIRISETRON MALEATE; 148611-75-0; UNII-0B4615FL1S; Mirisetron maleate (USAN); AC1O5KJ1; SCHEMBL121861; (Z)-but-2-enedioic acid;1-cyclohexyl-N-[(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl]-4-oxoquinoline-3-carboxamide. Grades: 98%. CAS No. 148611-75-0. Molecular formula: C28H35N3O6. Mole weight: 509.60. | |
| Mosapride | Mosapride, a selective agonist of 5-HT4 receptor, could be used as a gastroprokinetic agent. It is also found to be a 5-HT3 receptor antagonist. Synonyms: 4-amino-5-chloro-2-ethoxy-N-((4-(4-fluorobenzyl)-2-morpholinyl)methyl)benzamide. Grades: 98%. CAS No. 112885-41-3. Molecular formula: C21H25ClFN3O3. Mole weight: 421.90. | |
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