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Acetylcysteine Acetylcysteine (N-Acetylcysteine) is a mucolytic agent which reduces the thickness of the mucus. Acetylcysteine is a ROS inhibitor. Acetylcysteine is a cysteine precursor, prevents hemin-induced ferroptosis by neutralizing toxic lipids generated by arachidonate-dependent activity of 5-lipoxygenases. Acetylcysteine induces cell apoptosis. Acetylcysteine also has anti- influenza virus activities. In addition, Acetylcysteine ??is the most stable form of cysteine ??during drug delivery and can be used in disulfidptosis studies [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Natural products. Alternative Names: N-Acetylcysteine; N-Acetyl-L-cysteine; NAC. CAS No. 616-91-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 10 g. Product ID: HY-B0215. MedChemExpress MCE
Acetylcysteine EP Impurity A Acetylcysteine EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,2'R)-3,3'-disulfanediylbis(2-aminopropanoic acid). CAS No. 56-89-3. Molecular Formula: C6H12N2O4S2. Mole Weight: 240.30. Catalog: APB56893. Alfa Chemistry Analytical Products 2
Acetylcysteine EP Impurity B Acetylcysteine EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-2-amino-3-mercaptopropanoic acid. CAS No. 52-90-4. Molecular Formula: C3H7NO2S. Mole Weight: 121.16. Catalog: APB52904. Alfa Chemistry Analytical Products 3
Acetylcysteine EP Impurity C Acetylcysteine EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,2'R)-3,3'-disulfanediylbis(2-acetamidopropanoic acid). CAS No. 5545-17-5. Molecular Formula: C10H16N2O6S2. Mole Weight: 324.37. Catalog: APB5545175. Alfa Chemistry Analytical Products 2
Acetylcysteine EP Impurity D Acetylcysteine EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-2-acetamido-3-(acetylthio)propanoic acid. CAS No. 18725-37-6. Molecular Formula: C7H11NO4S. Mole Weight: 205.23. Catalog: APB18725376. Alfa Chemistry Analytical Products
Acetylcysteine Impurity 1 Acetylcysteine Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,2'R)-3,3'-thiobis(2-acetamidopropanoic acid). Molecular Formula: C10H16N2O6S. Mole Weight: 292.31. Catalog: APB02823. Alfa Chemistry Analytical Products 3
Acetylcysteine Impurity 10 Acetylcysteine Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-2-acetamido-3-disulfanylpropanoic acid. Molecular Formula: C5H9NO3S2. Mole Weight: 195.26. Catalog: APB02816. Alfa Chemistry Analytical Products 3
Acetylcysteine Impurity 11 Acetylcysteine Impurity 11. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R) -2-acetamido-3- ( (2- ( (carboxymethyl) amino) acetyl) thio) propanoic acid. Molecular Formula: C9H14N2O6S. Mole Weight: 278.28. Catalog: APB02817. Alfa Chemistry Analytical Products 3
Acetylcysteine Impurity 12 Acetylcysteine Impurity 12. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-3-(acetylthio)-2-(N-ethylacetamido)propanoic acid. Molecular Formula: C9H15NO4S. Mole Weight: 233.28. Catalog: APB02818. Alfa Chemistry Analytical Products 3
Acetylcysteine Impurity13 Acetylcysteine Impurity13. Uses: For analytical and research use. Group: Impurity standards. CAS No. 137698-08-9. Molecular Formula: C8H14N2O5S. Mole Weight: 250.27. Catalog: APB137698089. Alfa Chemistry Analytical Products 2
Acetylcysteine Impurity 13 Acetylcysteine Impurity 13. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-2-acetamido-3-mercaptopropanoic acid. CAS No. 26117-28-2. Molecular Formula: C5H9NO3S. Mole Weight: 163.19. Catalog: APB26117282. Alfa Chemistry Analytical Products 2
Acetylcysteine Impurity14 Acetylcysteine Impurity14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2578-27-0. Molecular Formula: C6H13NO2Se. Mole Weight: 210.15. Catalog: APB2578270. Alfa Chemistry Analytical Products 2
Acetylcysteine Impurity 14 DiHCl S-(2-acetimidamidoethyl)-L-homocysteine Hydrochloride is one of Acetylcysteine impurities. It has potential anticancer activity against tumor cell growth. Synonyms: S-(2-acetimidamidoethyl)-L-homocysteine, hydrochloride (1:2). CAS No. 438542-17-7. Molecular formula: C8H17N3O2S.2HCl. Mole weight: 292.23. BOC Sciences
Acetylcysteine Impurity 15 Acetylcysteine Impurity 15. Uses: For analytical and research use. Group: Impurity standards. CAS No. 357172-63-5. Molecular Formula: C9H16N4O3S. Mole Weight: 260.31. Catalog: APB357172635. Alfa Chemistry Analytical Products 2
Acetylcysteine Impurity 16 Acetylcysteine Impurity 16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 14226-97-2. Molecular Formula: C5H7NO3S. Mole Weight: 161.18. Catalog: APB14226972. Alfa Chemistry Analytical Products
Acetylcysteine Impurity 17 Acetylcysteine Impurity 17. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C7H11NO6S. Mole Weight: 237.23. Catalog: APB06399. Alfa Chemistry Analytical Products 3
Acetylcysteine Impurity 18 Acetylcysteine Impurity 18. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C5H8N2O4S. Mole Weight: 192.19. Catalog: APB06400. Alfa Chemistry Analytical Products 3
Acetylcysteine Impurity 19 Acetylcysteine Impurity 19. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: sodium 2-methyl-4,5-dihydrothiazole-4-carboxylate. CAS No. 15058-19-2. Molecular Formula: C5H6NNaO2S. Mole Weight: 167.16. Catalog: APB15058192. Alfa Chemistry Analytical Products
Acetylcysteine Impurity 2 Acetylcysteine Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,2'R)-3,3'-thiobis(2-aminopropanoic acid). Molecular Formula: C6H12N2O4S. Mole Weight: 208.24. Catalog: APB02822. Alfa Chemistry Analytical Products 3
Acetylcysteine Impurity 20 (Monohydrate) Acetylcysteine Impurity 20 (Monohydrate). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R)-2-amino-3-sulfinopropanoic acid hydrate. CAS No. 207121-48-0. Molecular Formula: C3H7NO4S·H2O. Mole Weight: 171.17. Catalog: APB207121480. Alfa Chemistry Analytical Products 2
Acetylcysteine Impurity 21 Acetylcysteine Impurity 21. Uses: For analytical and research use. Group: Impurity standards. CAS No. 21612-28-2. Molecular Formula: C17H20N4O5. Mole Weight: 360.37. Catalog: APB21612282. Alfa Chemistry Analytical Products 2
Acetylcysteine Impurity 22 Acetylcysteine Impurity 22. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2304-94-1. Molecular Formula: C11H13NO4. Mole Weight: 223.23. Catalog: APB2304941. Alfa Chemistry Analytical Products 2
Acetylcysteine Impurity 23 Acetylcysteine Impurity 23. Uses: For analytical and research use. Group: Impurity standards. CAS No. 14997-59-2. Molecular Formula: C11H17N3O3. Mole Weight: 239.28. Catalog: APB14997592. Alfa Chemistry Analytical Products 2
Acetylcysteine Impurity 24 Acetylcysteine Impurity 24. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C10H16N2O6S. Mole Weight: 292.31. Catalog: APB06401. Alfa Chemistry Analytical Products 3
Acetylcysteine Impurity 25 Acetylcysteine Impurity 25. Uses: For analytical and research use. Group: Impurity standards. CAS No. 19547-88-7. Molecular Formula: C8H13NO4S. Mole Weight: 219.26. Catalog: APB19547887. Alfa Chemistry Analytical Products
Acetylcysteine Impurity 27 Acetylcysteine Impurity 27. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2467738-84-5. Molecular Formula: C15H19FN2O6. Mole Weight: 342.32. Catalog: APB2467738845. Alfa Chemistry Analytical Products 2
Acetylcysteine Impurity 3 (2R)-2-acetamido-3-sulfopropanoic acid is one of Acetylcysteine impurities. It has potential anticancer activity against tumor cell growth. Synonyms: acetyl(sulfo)-D-alanine. CAS No. 79560-92-2. Molecular formula: C5H9NO6S. Mole weight: 211.19. BOC Sciences
Acetylcysteine Impurity 3 Acetylcysteine Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R)-2-acetamido-3-sulfinopropanoic acid. CAS No. 282727-77-9. Molecular Formula: C5H9NO5S. Mole Weight: 195.19. Catalog: APB282727779. Alfa Chemistry Analytical Products 2
Acetylcysteine Impurity 4 Acetylcysteine Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-2-acetamido-3-sulfopropanoic acid. CAS No. 79560-92-2. Molecular Formula: C5H9NO6S. Mole Weight: 211.19. Catalog: APB79560922. Alfa Chemistry Analytical Products 3
Acetylcysteine Impurity 4 Disodium Salt Acetylcysteine Impurity 4 Disodium Salt is one of Acetylcysteine impurities. It has potential anticancer activity against tumor cell growth. Synonyms: Acetyl(sulfinato)-D-alaninate, sodium salt (1:2). Molecular formula: C5H7NO5SNa2. Mole weight: 239.16. BOC Sciences
Acetylcysteine Impurity 5 Acetylcysteine Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-2-methyl-4,5-dihydrothiazole-4-carboxylic acid. Molecular Formula: C5H7NO2S. Mole Weight: 145.18. Catalog: APB02821. Alfa Chemistry Analytical Products 3
Acetylcysteine Impurity 6 Acetylcysteine Impurity 6 is one of Acetylcysteine impurities. It has potential anticancer activity against tumor cell growth. Molecular formula: C5H9NO3S. Mole weight: 163.19. BOC Sciences
Acetylcysteine Impurity 6 Acetylcysteine Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: sodium (R)-2-methyl-4,5-dihydrothiazole-4-carboxylate. Molecular Formula: C5H6NNaO2S. Mole Weight: 167.16. Catalog: APB02820. Alfa Chemistry Analytical Products 3
Acetylcysteine Impurity 7 Acetylcysteine Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 66185-37-3(HCl salt); (R)-3-(acetylthio)-2-aminopropanoic acid. CAS No. 15312-11-5. Molecular Formula: C5H9NO3S. Mole Weight: 163.19. Catalog: APB15312115. Alfa Chemistry Analytical Products
Acetylcysteine Impurity 7 Acetylcysteine Impurity 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 74401-71-1. Molecular Formula: C7H11NO4S. Mole Weight: 205.23. Catalog: APB74401711. Alfa Chemistry Analytical Products 3
Acetylcysteine Impurity8 Acetylcysteine Impurity8. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C5H7NNa2O5S. Mole Weight: 239.15. Catalog: APB06398. Alfa Chemistry Analytical Products 3
Acetylcysteine Impurity 8 Acetylcysteine Impurity 8. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-Acetyl-L-cystine; (R)-2-acetamido-3-(((R)-2-amino-2-carboxyethyl)disulfanyl)propanoic acid. CAS No. 25779-79-7. Molecular Formula: C8H14N2O5S2. Mole Weight: 282.34. Catalog: APB25779797. Alfa Chemistry Analytical Products 2
Acetylcysteine Impurity 8 N-Acetyl-S-(3-amino-2-hydroxy-3-oxopropyl)-L-cysteineis one of Acetylcysteine impurities. It has potential anticancer activity against tumor cell growth. Synonyms: N-Acetyl-S-(2-carbamoyl-2-hydroxyethyl)cysteine; SCHEMBL21490409; DTXSID401025770; 137698-08-9; N-acetyl-S-(2-carbamoyl-2-hydroxyethyl)-cysteine; Q58328438. CAS No. 137698-08-9. Molecular formula: C8H14N2O5S. Mole weight: 250.27. BOC Sciences
Acetylcysteine Impurity9 Acetylcysteine Impurity9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 498-40-8. Molecular Formula: C3H7NO5S. Mole Weight: 169.15. Catalog: APB498408. Alfa Chemistry Analytical Products 2
Acetylcysteine Impurity 9 Acetylcysteine Impurity 9. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-4-(mercaptomethyl)-2-methyloxazol-5(4H)-one. Molecular Formula: C5H7NO2S. Mole Weight: 145.18. Catalog: APB02819. Alfa Chemistry Analytical Products 3
Acetylcysteine Impurity 9 Sodium Salt Acetylcysteine Impurity 9 Sodium Salt is one of Acetylcysteine impurities. It has potential anticancer activity against tumor cell growth. Synonyms: N-Acetyl-S-(3-hydroxypropyl)-L-cysteine, sodium salt (1:1). Molecular formula: C8H14NO4SNa. Mole weight: 243.26. BOC Sciences
Acetylcysteine Impurity D N,S-Diacetyl-L-cysteine is a double-prodrugs of L-cysteine: differential protection against acetaminophen-induced hepatotoxicity in mice. Synonyms: N,S-Diacetyl-L-cysteine; N-Acetylcysteine Acetate; Dacisteine; N,S-Diacetylcysteine; N-Acetylcysteine S-Acetate. Grades: > 95%. CAS No. 18725-37-6. Molecular formula: C7H11NO4S. Mole weight: 205.23. BOC Sciences
Captopril-N-acetylcysteine Disulfide Captopril-N-acetylcysteine Disulfide is a metabolite of Captopril, which is an orally active angiotensin-converting enzyme (ACE) inhibitor used as an antihypertensive agent. Synonyms: 1-[(2S)-3-[[(2R)-2-(Acetylamino)-2-carboxyethyl]dithio]-2-methyl-1-oxopropyl]-L-proline; ((S)-3-(((R)-2-acetamido-2-carboxyethyl)disulfaneyl)-2-methylpropanoyl)-L-proline; 1-[(2S)-3-{[(2R)-2-Acetamido-2-carboxyethyl]disulfanyl}-2-methylpropanoyl]-L-proline; Captopril Related Compound 10. Grades: 95%. CAS No. 78636-31-4. Molecular formula: C14H22N2O6S2. Mole weight: 378.46. BOC Sciences 8
N-Acetylcysteine amide N-Acetylcysteine amide is a cell membranes and blood brain barrier permeant thiol antioxidant and neuroprotective agent, reduces ROS production. Uses: Scientific research. Group: Signaling pathways. CAS No. 38520-57-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110256. MedChemExpress MCE
N-Acetylcysteine Amide N-Acetylcysteine amide is a blood brain barrier permeant and cell membranes thiol antioxidant with anti-inflamatory activity via regulation of activation of NF-κB and HIF-1α as well as modulation of ROS. It readily crosses cell membranes, replenishes intracellular GSH, and defends the cell from oxidative stress. It may be used in research and exploration for the treatment of radiation exposure, neurodegeneration and other oxidation-mediated disorders. It is also used for the treatment of acquired immune deficiency syndrome and HIV infection. It is also used as an authentic imaging probe for accurate tracing of cells viability from beginning to end to distinguish apoptotic and necrotic cells. It improves neuronal mitochondrial bioenergetics, reduces tissue damage and enhances behavioral recovery in rats following traumatic brain injury. It is a neuroprotective agent. Synonyms: (2R)-2-(Acetylamino)-3-mercaptopropanamide;N-Acetyl-L-cysteinamide. CAS No. 38520-57-9. Molecular formula: C5H10N2O2S. Mole weight: 162.21. BOC Sciences 9
Ac-AVP Ac-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Vasopressin, N-acetyl-8-L-arginine-; Vasopressin, 1-(N-acetyl-L-cysteine)-8-arginine; Vasopressin, 8-acetylarginine; 1-Acetylcysteine-8-arginine-vasopressin; N-Acetyl-Vasopressin; N-acetyl-L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide; Ac-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); Ac-Vasopressin; N-Acetyl-8-L-argininevasopressin. CAS No. 38106-69-3. Molecular formula: C48H67N15O13S2. Mole weight: 1126.28. BOC Sciences 2
Ac-Oxytocin Ac-Oxytocin is an impurity of Oxytocin, which is a mammalian neurohypophysial hormone used as a vasodilator agent. Synonyms: Acetyl-L-cystyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparginyl-L-cystyl-L-leucyl-L-prolyl-L-glycinamide (disulfide bridge between cysteines); Cys(Ac)-Oxytocin; Ac-Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Disulfide bridge: Cys1-Cys6); Oxytocin, N-acetyl-; N(alpha)-Acetyloxytocin; N-Acetyloxytocin; Oxytocin, 1-(N-acetylcysteine). Grades: ≥95%. CAS No. 10551-48-1. Molecular formula: C45H68N12O13S2. Mole weight: 1049.23. BOC Sciences 2
Cystine Pharmacopeia & Metrological Institutes Standards; European Pharmacopoeia (Ph. Eur.); Pharmacopoeial Standards. Uses: For analytical and research use. Group: Reagents. Alternative Names: Acetylcysteine Imp. A (EP),L-Cystine. CAS No. 56-89-3. Pack Sizes: 200MG. IUPAC Name: (2R)-2-amino-3-[[(2R)-2-amino-2-carboxyethyl]disulfanyl]propanoic acid. Alfa Chemistry Analytical Products
N-Acetyl-L-cysteine N-Acetyl-L-cysteine is an antioxidant and precursor to glutathione. It has potential anticancer activity against tumor cell growth. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Acetylcysteine; N-Acetylcysteine; Mercapturic acid; Acetadote; (2R)-2-acetamido-3-sulfanylpropanoic acid. Grades: 95%. CAS No. 616-91-1. Molecular formula: C5H9NO3S. Mole weight: 163.19. BOC Sciences 9
N-Acetyl-L-Cysteine N-Acetyl-L-Cysteine. Categories: n-acetyl-l-cysteine; acetylcysteine. Pharma Resources International LLC
CA, FL & NJ
N-Acetyl-L-cysteine ethyl ester N-Acetyl-L-cysteine ethyl ester, a derivative of N-acetylcysteine, is acknowledged for its highly efficacious anti-inflammatory and antioxidant properties. This potent compound has been employed in numerous treatments, including those for cystic fibrosis and HIV-associated neuropathy. Apart from that, it is widely consumed as a dietary supplement due to its potentiality in enhancing liver and lung health. Synonyms: L-Cysteine, N-acetyl-, ethyl ester; Ethyl (2R)-2-acetamido-3-sulfanylpropanoate. CAS No. 59587-09-6. Molecular formula: C7H13NO3S. Mole weight: 191.245. BOC Sciences 9
N-Acetyl-L-cysteine ethyl ester N-Acetyl-L-cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine (NAC). N-Acetyl-L-cysteine ethyl ester exhibits enhanced cell permeability, and produce NAC and cysteine. N-Acetyl-L-cysteine ethyl ester increases circulating hydrogen sulfide (H 2 S) and can be used as an H 2 S producer. N-Acetyl-L-cysteine ethyl ester has the potential to substitute NAC as a mucolytic agent, and as a GSH-related antioxidant [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-Acetylcysteine ethyl ester; NACET. CAS No. 59587-09-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-134495. MedChemExpress MCE
N-Acetyl-L-cysteine, USP (non-animal) Antioxidant; mucolytic agent; anti-viral against influenza A viruses. Group: Biochemicals. Alternative Names: ACC; Acetadote; Acetilcysteina; Acetylcysteine; Airbron; Broncholysin; Brunac; Exomuc; Fabrol; Fluatox; Fluibiotic; Fluimicil; Fluimicil Infantil; N.alpha.-Acetylcysteine; Parvolex; Respaire; Syntemucol; Tixair. Grades: USP. CAS No. 616-91-1. Pack Sizes: 100g, 250g. Molecular Formula: C5H9NO3S, Molecular Weight: 163.2. US Biological Life Sciences. USBiological 1
Worldwide
N,S-Diacetyl-L-cysteine A double-prodrugs of L-cysteine. Group: Biochemicals. Alternative Names: N-Acetylcysteine. Grades: Highly Purified. CAS No. 18725-37-6. Pack Sizes: 500mg. US Biological Life Sciences. USBiological 2
Worldwide
Sodium 2-Methyl-4,5-Dihydro-1,3-Thiazol-4-Carboxylate Sodium 2-Methyl-4,5-Dihydro-1,3-Thiazol-4-Carboxylate is an impurity of Acetylcysteine. Synonyms: 2-methyl-4,5-dihydro-1,3-thiazole-4-carboxylate; 2-Methyl-2-thiazoline-4-carboxylic acid sodium salt; Acetylcysteine Impurity 1 Sodium Salt. Grades: > 95%. CAS No. 15058-19-2. Molecular formula: C5H6NO2SNa. Mole weight: 167.16. BOC Sciences 8
Sodium L-ascorbyl-2-phosphate Sodium L-ascorbyl-2-phosphate is a stable and long-lasting vitamin C derivative. It may be used in cell differentiation and tissue engineering applications, such as the repression of dihydrotestosterone-induced dickkopf-1 expression. lt exhibits synergistic protection of hMSCs under oxidative stress in combination with N-acetylcysteine. It could increase myogenin gene expression and promote differentiation in L6 muscle cells. It is also used in biocatalytic dephosphorylation for electric power generation and electrochemical detection assays. Uses: Face care. Synonyms: L-Ascorbicacid, 2-(dihydrogenphosphate), trisodiumsalt; Sodium (R)-5-((S)-1,2-dihydroxyethyl)-4-hydroxy-2-oxo-2,5-dihydrofuran-3-yl phosphate; 2-Phospho-L-ascorbic acid trisodium salt. Grades: >98%. CAS No. 66170-10-3. Molecular formula: C6H6Na3O9P. Mole weight: 322.05. BOC Sciences
ZZW-115 ZZW-115 is a potent NUPR1 inhibitor. ZZW-115 induces ferroptosis in a mitochondria-dependent manner. ZZW-115 induces ROS accumulation followed by a ferroptotic cell death, which could be prevented by ferrostatin-1 (Fer-1) and ROS-scavenging agents. In addition, ZZW-115-treatment increases the accumulation of hydroperoxided lipids in these cells. ZZW-115-induced mitochondrial morphological changes, compatible with the ferroptotic process, as well as mitochondrial network disorganization and strong mitochondrial metabolic dysfunction, which are rescued by both Fer-1 and N-acetylcysteine (NAC). Of note, the expression of TFAM, a key regulator of mitochondrial biogenesis, is downregulated by ZZW-115. Group: Inhibitors. Alternative Names: ZZW-115; ZZW 115; ZZW115. CAS No. 801991-87-7. Molecular formula: C24H31F3N4S. Mole weight: 464.6. Appearance: Solid powder. Purity: >98%. IUPACName: N,N-dimethyl-2-(4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)piperazin-1-yl)ethan-1-amine. Canonical SMILES: FC (C (C=C1N2CCCN3CCN (CCN (C)C)CC3)=CC=C1SC4=C2C=CC=C4) (F)F. Catalog: ACM801991877. Alfa Chemistry.
HJC0197 HJC0197 is a erythromycin propionate-N-acetylcysteinate inhibitor (EPAC). IC50 value is 5.9 μM for Epac2. HJC0197 can inhibit Epac1-mediated Rap1-GDP exchange activity at 25 μM, but it has no effect on cAMP-induced type I and II PKA activity at this concentration. HJC0197 can be used to study the role of Epac signaling in chondrogenesis in chicken micromass cultures. EPAC inhibitor may prevent pancreatic cancer cell migration and invasion. Uses: Study the role of epac signaling. Synonyms: HJC0197; HJC-0197; HJC 0197. 4-cyclopentyl-2-((2,5-dimethylbenzyl)thio)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile. Grades: 98%. CAS No. 1383539-73-8. Molecular formula: C19H21N3OS. Mole weight: 339.45. BOC Sciences 9

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