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The reaction is effectively irreversible, favouring oxopropanoate (malonic semialdehyde) and its tautomers. Also acts on but-3-ynoate forming acetoacetate. The mechanism appears to involve hydration of the acetylene to 3-hydroxypropenoate, which will spontaneously tautomerize to 3-oxopropanoate. It is thus analogous to EC 4.1.1.78, acetylenedicarboxylate decarboxylase, in its mechanism. Group: Enzymes. Synonyms: acetylenemonocarboxylate hydratase; alkynoate hydratase; acetylenemonocarboxylate hydrase; acetylenemonocarboxylic acid hydrase; malonate-semialdehyde dehydratase; 3-oxopropanoate hydro-lyase. Enzyme Commission Number: EC 4.2.1.27. CAS No. 9024-26-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5018; acetylenecarboxylate hydratase; EC 4.2.1.27; 9024-26-4; acetylenemonocarboxylate hydratase; alkynoate hydratase; acetylenemonocarboxylate hydrase; acetylenemonocarboxylic acid hydrase; malonate-semialdehyde dehydratase; 3-oxopropanoate hydro-lyase. Cat No: EXWM-5018.
acetylenedicarboxylate decarboxylase
The mechanism appears to involve hydration of the acetylene and decarboxylation of the oxaloacetic acid formed, although free oxaloacetate is not an intermediate. It is thus analogous to EC 4.2.1.27 (acetylenecarboxylate hydratase) in its mechanism. Group: Enzymes. Synonyms: acetylenedicarboxylate hydratase; acetylenedicarboxylate hydrase; acetylenedicarboxylate carboxy-lyase. Enzyme Commission Number: EC 4.1.1.78. CAS No. 72561-10-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4826; acetylenedicarboxylate decarboxylase; EC 4.1.1.78; 72561-10-5; acetylenedicarboxylate hydratase; acetylenedicarboxylate hydrase; acetylenedicarboxylate carboxy-lyase. Cat No: EXWM-4826.
Acetylenedicarboxylic acid
Acetylenedicarboxylic acid (CAS# 142-45-0) is used as an electrolyte in the fabrication of anodic nanoporous alumina. It is also used as a reagent in the synthesis of several organic compounds including that of derivatives of metronodazole (antibiotic and antiprotozoal medication) which display increased antimicrobial and antiparasitic properties. Synonyms: but-2-ynedioic acid. CAS No. 142-45-0. Molecular formula: C4H2O4. Mole weight: 114.06.
Acetylenedicarboxylic acid
Acetylenedicarboxylic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 142-45-0. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C4H2O4. US Biological Life Sciences.
Acetylenedicarboxylic acid monopotassium salt (CAS# 928-04-1) is a useful research chemical. Synonyms: potassium;4-hydroxy-4-oxobut-2-ynoate. CAS No. 928-04-1. Molecular formula: C4HKO4. Mole weight: 152.15.
acetylene hydratase
This is a non-redox-active enzyme that contains two molybdopterin guanine dinucleotide (MGD) cofactors, a tungsten centre and a cubane type [4Fe-4S] cluster.The tungsten centre binds a water molecule that is activated by an adjacent aspartate residue, enabling it to attack acetylene bound in a distinct hydrophobic pocket. Ethylene cannot act as a substrate. Group: Enzymes. Synonyms: AH; acetaldehyde hydro-lyase. Enzyme Commission Number: EC 4.2.1.112. CAS No. 75788-81-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4952; acetylene hydratase; EC 4.2.1.112; 75788-81-7; AH; acetaldehyde hydro-lyase. Cat No: EXWM-4952.
1-Iodo-2- (trimethylsilyl) acetylene is a useful chemical reagent. Group: Biochemicals. Grades: Highly Purified. CAS No. 18163-47-8. Pack Sizes: 250mg, 1g. Molecular Formula: C5H9ISi, Molecular Weight: 224.11. US Biological Life Sciences.
(2-Hydroxyethyl)acetylene 98+% (GC). Group: Biochemicals. Grades: GC. Pack Sizes: 5g, 25g, 100g, 250g, 1Kg. US Biological Life Sciences.
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3-Ethynylaniline (3-Aminophenyl acetylene)
5g Pack Size. Group: Building Blocks, Organics. Formula: C8H7N. CAS No. 54060-30-9. Prepack ID 19109849-5g. Molecular Weight 117.15. See USA prepack pricing.
The enzyme, characterized from the plant Crepis alpina, converts the double bond at position 12 of linoleate into a triple bond. The product is the main fatty acid found in triacylglycerols in the seed oil of Crepis alpina. Group: Enzymes. Enzyme Commission Number: EC 1.14.19.39. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1003; acyl-lipid Δ12-acetylenase; EC 1.14.19.39. Cat No: EXWM-1003.
acyl-lipid Δ6-acetylenase
The enzyme, characterized from the moss Ceratodon purpureus, converts the double bond at position 6 of γ-linolenate and stearidonate into a triple bond. The product of the latter, dicranin, is the main fatty acid found in C. purpureus. The enzyme contains a cytochrome b5 domain that acts as the direct electron donor to the desaturase active site. The enzyme also has the activity of EC 1.14.19.47, acyl-lipid (9-3)-desaturase. Group: Enzymes. Enzyme Commission Number: EC 1.14.19.38. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1002; acyl-lipid Δ6-acetylenase; EC 1.14.19.38. Cat No: EXWM-1002.
Bis(trimethylsilyl)acetylene is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 14630-40-1. Pack Sizes: 5 g; 10 g. Product ID: HY-W016961.
Cyclopropyl acetylene. Group: Biochemicals. Grades: Highly Purified. CAS No. 6746-94-7. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C5H6. US Biological Life Sciences.
Worldwide
Dimethyl acetylene dicarboxylate
Dimethyl acetylene dicarboxylate. Group: Biochemicals. Grades: Highly Purified. CAS No. 762-42-5. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C6H6O4. US Biological Life Sciences.
Worldwide
Dimethyl acetylenedicarboxylate 98+%
Dimethyl acetylenedicarboxylate 98+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g, 250g, 1Kg. US Biological Life Sciences.
Worldwide
γ-Acetylenic GABA hydrochloride
γ-Acetylenic GABA (GAG) hydrochloride is an irreversible inhibitor of GABA-transaminase. γ-Acetylenic GABA hydrochloride can increase the concentration of GABA in rat brain [1] [2] [3]. γ-Acetylenic GABA (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GAG hydrochloride. CAS No. 103451-26-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-131693A.
hex-5-enoyl-[acyl-carrier protein] acetylenase
The enzyme, characterized from the marine cyanobacterium Moorea producens, is involved in production of the ion channel blocker jamaicamide A. It is specific for hexanoate or hex-5-enoate loaded onto a dedicated acyl-carrier protein (JamC), which is encoded by a gene in the same operon. Group: Enzymes. Synonyms: jamB (gene name). Enzyme Commission Number: EC 1.14.19.40. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1005; hex-5-enoyl-[acyl-carrier protein] acetylenase; EC 1.14.19.40; jamB (gene name). Cat No: EXWM-1005.
hydroxyl surface groups. Uses: They adopt nanometer-scale dimensions, and can be ideal candidates for drug delivery, gene transfection applications. Group: Dendrimers. Alternative Names: Dendron-G5-Acetylene-OH. Pack Sizes: 250 mg in glass insert. Molecular formula: 3655.64. Mole weight: C158H252O94. 0.97.
Dendrimers and dendrons are symmetrically branched polymer structures that possess a well-defined spatial distribution of functional groups. Dendrimers are chemically modified by attaching poly ethylene glycol (PEG) molecule to increase its solubility and prolong circulation half-life."Clickable groups", such as primary acetylenes, are introduced to the mono dispersed dendritic structures, using "click" chemistry. These acetylene groups, attached to Bis-MPA based dendrons, allow it to form the conjugates with bioactive moieties such as carbohydrate, fluorescent dyes, disaccharides etc. Uses: The proposed uses are: as an efficient drug delivery system. in vitro toxicological studies; in vivo via radionuclide labeling and optical imaging biosensors;dip pen nanolithography. Group: Dendrimers. Alternative Names: PFD-G3-PEG6k-Acetylene, Dendron functionalized PEG acetylene, generation 3, Bis[2,2-bis(hydroxymethyl)propanoic acid] PEG, PEG-6000, Bis-MPA poly(ethylene glycol). Pack Sizes: Packaging 500 mg in glass insert. Molecular formula: PEG average Mn 6000 (n~130, esterified with 16 acetylene groups) Mn 7500-9500 (by NMR) average Mn 8000.
10-Undecyn-1-ol is an acetylenic alcohol with antifungal activity. 10-Undecyn-1-ol is used in the esterification of pentanoic and stearic acids in the presence of various lipase. Group: Biochemicals. Alternative Names: 1-Undecyn-11-ol; 11-Hydroxy-1-undecyne; Undec-10-yn-1-ol. Grades: Highly Purified. CAS No. 2774-84-7. Pack Sizes: 1g. US Biological Life Sciences.
1,2-Bis(4-methoxyphenyl)ethyne, a pharmacological compound exhibiting compelling prospects for biomedical study. Through its demonstrated inhibition of cell proliferation, it holds potential as a novel therapeutic approach towards quenching breast and lung cancer. An exciting candidate warranting continued investigation. Synonyms: Bis(4-methoxyphenyl)acetylene; 1,1'-(1,2-Ethindiyl)bis(4-methoxybenzol); 1,1'-(1,2-Ethynediyl)bis(4-methoxybenzene); Acetylene, bis(p-methoxyphenyl)-; 1,2-Bis(4-methoxyphenyl)acetylene; 1,2-Bis(p-anisyl)acetylene. Grades: 95%. CAS No. 2132-62-9. Molecular formula: C16H14O2. Mole weight: 238.28.
1,2-Diphenyl-3,5-pyrazolidinedione
1,2-Diphenyl-3,5-pyrazolidinedione is a reactant used in organic synthesis such as in the the preparation of inhibitors of UDP-N-acetylenolpyruvyl glucosamine reductase. Group: Biochemicals. Grades: Highly Purified. CAS No. 2652-77-9. Pack Sizes: 250mg, 1g. Molecular Formula: C15H12N2O2, Molecular Weight: 252.27. US Biological Life Sciences.
Worldwide
1,4-Dichloro-2-butyne
1,4-Dichloro-2-butyne used in the synthesis of 1,4-disubstituted 1,2,3-triazoles. Also, it is used in the approach of the 20S-camptothecin family of antitumor agents. Group: Biochemicals. Alternative Names: 1,4-Dichloro-2-butyne; 1,4-Dichlorobutyne; Bis (chloromethyl) acetylene; NSC 30603. Grades: Highly Purified. CAS No. 821-10-3. Pack Sizes: 5g. US Biological Life Sciences.
1-Ethynylcyclohexanol. Group: Biochemicals. Alternative Names: (1-Hydroxycyclohexyl) acetylene; (1-Hydroxycyclohexyl) ethyne; 1-Ethynyl-1-cyclohexanol; 1-Ethynyl-1-hydroxycyclohexane; 1-Ethynylcyclohexanol; 1-Hydroxy-1-ethynylcyclohexane; Ethynylcyclohexanol; NSC 8194. Grades: Highly Purified. CAS No. 78-27-3. Pack Sizes: 10g. Molecular Formula: C8H12O, Molecular Weight: 124.18. US Biological Life Sciences.
Worldwide
1-Ethynylpyrene
1-Ethynylpyrene is an aryl acetylenic inhibitor of cytochromes P450 1A1 , 1A2 , and 2B1 with IC 50 s of 0.18, 0.32, and 0.04 μM, respectively [1]. 1-Ethynylpyrene is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 34993-56-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg. Product ID: HY-131452.
(1'R,2'R,3aS,3"aS,8aR,8"aR)-(+)-3,3",3a,3"a,8,8",8a,8"a-Octahydrodispiro{2H-indeno[1,2-d]oxazole-2,1'-cyclohexane-2',2"-[2H]indeno[1,2-d]oxazole} WOLF BISOXAZOLIDINE
Catalyst used in the asymmetric addition of diethylzinc to aldehydes - synthesis of chiral alcohols. Catalysts used in the asymmetric addition of acetylenes and silylacetylenes to aldehydes. Catalyst used in the asymmetric addition of nitromethane to aldehydes - synthesis of β-hydroxynitromethanes. Group: Heterocyclic organic compound. Alternative Names: WOLF Bisoxazolidine;MFCD11973793;(1'R, 2'R, 3aS, 3"aS, 8aR, 8"aR)-(+)-3, 3".3a, 3"a, 8, 8", 8a, 8"a-Octahydrodispiro{2H-indeno[1, 2-d]oxazole-2, 1'-cyclohexane-2', 2"-[2H]indeno[1, 2-d]oxazole};947515-50-6. CAS No. 947515-50-6. Molecular formula: C24H26N2O2. Mole weight: 374.484g/mol. Canonical SMILES: C1CCC2 (C3 (C1)NC4C (O3)CC5=CC=CC=C45)NC6C (O2)CC7=CC=CC=C67. Catalog: ACM947515506.
2,4,6-Collidine is an reagent used for various synthetic preparations such as the synthesis of methylated pyridines by three-componet catalytic condensation of acetylene, acetone and ammonia. Group: Biochemicals. Alternative Names: 2,4,6-Trimethylpyridine; NSC 460; s-Collidine; sym-Collidine; α, γ, α'-Collidine; γ-Collidine. Grades: Highly Purified. CAS No. 108-75-8. Pack Sizes: 10g. US Biological Life Sciences.
Worldwide
2,4,7,9-Tetramethyl-5-decyne-4,7-diol
An acetylene glycol derivative used in water-based coatings and has both antifoaming and surfactant properties. It is highly toxic and have been found in acrylic adhesives used for food packaging multilayers manufacturing. Group: Polymer/macromolecule. Alternative Names: Surfynol 104. CAS No. 126-86-3. Molecular formula: C14H26O2. Mole weight: 226.35. Appearance: Waxy-like white crystal. Purity: 0.98. IUPACName: 2,4,7,9-tetramethyldec-5-yne-4,7-diol. Canonical SMILES: CC(C)CC(C)(O)C#CC(C)(O)CC(C)C. Density: 0.89. ECNumber: 204-809-1. Catalog: ACM126863.
2,4,7,9-Tetramethyl-5-decyne-4,7-diol
An acetylene glycol derivative used in water-based coatings and has both antifoaming and surfactant properties. It is highly toxic and have been found in acrylic adhesives used for food packaging multilayers manufacturing. Group: Self-assembly materials. Alternative Names: Surfynol 104. CAS No. 126-86-3. Product ID: 2,4,7,9-tetramethyldec-5-yne-4,7-diol. Molecular formula: 226.35. Mole weight: C14H26O2. CC(C)CC(C)(O)C#CC(C)(O)CC(C)C. LXOFYPKXCSULTL-UHFFFAOYSA-N. 98%.
2,4,7,9-Tetramethyl-5-decyne-4,7-diol ethoxylate
2,4,7,9-Tetramethyl-5-decyne-4,7-diol ethoxylate. Uses: Surfactant. reduces surface tension; wetting agent, defoamer, and emulsifier for emulsion polymerization. Group: Self-assembly materials. Alternative Names: 2,4,7,9-tetramethyl-5-decyne-4,7-diol, Acetylenol EL, 2,4,7,9-Tetramethyl-5-decyne-4,7-diol-ethylene oxide adduct. CAS No. 9014-85-1. Pack Sizes: Packaging 100 mL in poly bottle. Product ID: ethane-1,2-diol; 2,4,7,9-tetramethyldec-5-yne-4,7-diol. Molecular formula: 288.42g/mol. Mole weight: (CH3)2CHCH2C (CH3)[ (-OCH2CH2-)mOH]C?CC (CH3)[ (-OCH2CH2-)nOH]CH2CH (CH3)2. OCCO.CC(C)CC(C)(O)C#CC(C)(O)CC(C)C. 1S/C14H26O2.C2H6O2/c1-11(2)9-13(5, 15)7-8-14(6, 16)10-12(3)4;3-1-2-4/h11-12, 15-16H, 9-10H2, 1-6H3;3-4H, 1-2H2. SUHUKEQAOUOUJO-UHFFFAOYSA-N.
2,4,7,9-Tetramethyl-5-decyne-4,7-diol ethoxylate
Surfactant. Reduces surface tension; wetting agent, defoamer, and emulsifier for emulsion polymerization. Group: Polymer/macromolecule. Alternative Names: 2,4,7,9-tetramethyl-5-decyne-4,7-diol, Acetylenol EL, 2,4,7,9-Tetramethyl-5-decyne-4,7-diol-ethylene oxide adduct. CAS No. 9014-85-1. Molecular formula: (CH3)2CHCH2C (CH3)[ (-OCH2CH2-)mOH]C?CC (CH3)[ (-OCH2CH2-)nOH]CH2CH (CH3)2. Mole weight: 288.42g/mol. IUPACName: ethane-1,2-diol;2,4,7,9-tetramethyldec-5-yne-4,7-diol. Canonical SMILES: OCCO.CC(C)CC(C)(O)C#CC(C)(O)CC(C)C. Density: 1.04 g/mL at 25 °C. ECNumber: 500-022-5. Catalog: ACM9014851-1.
2-Nonyne is used in the studies of certian bisubstituted acetylenic hydrocarbons. Group: Biochemicals. Grades: Highly Purified. CAS No. 19447-29-1. Pack Sizes: 1g, 2.5g. Molecular Formula: C9H16, Molecular Weight: 124.22. US Biological Life Sciences.
Heterocyclic Organic Compound. CAS No. 1102-00-2. Molecular formula: C22H22O4. Mole weight: 350.408. Purity: 0.98. IUPACName: Addukt aus dimerem Cyclooctatetraen (F: 76grad) und Acetylendicarbonsa. Catalog: ACM1102002.
3-Amino-3-methyloxetane
3-Amino-3-methyloxetane is a useful reagent in study of allosteric agonism structure-activity relationships in an acetylene series of metabotropic glutamate receptor 5 Positive Allosteric Modulator (PAMs). Group: Biochemicals. Grades: Highly Purified. CAS No. 874473-14-0. Pack Sizes: 100mg, 250mg. Molecular Formula: C4H9NO, Molecular Weight: 87.12. US Biological Life Sciences.
Worldwide
3-Ethynylaniline
Reagent in the preparation of a metabolite of Erlotinib. Group: Biochemicals. Alternative Names: (3-Ethynylphenyl)amine; (m-Aminophenyl)acetylene; 1-Amino-3-ethynylbenzene; 3-Acetylenylaniline-d4; 3-Amino-1-ethynylbenzene; 3-Ethynylaniline; 3-Ethynylbenzenamine; m-Ethynylaniline. Grades: Highly Purified. CAS No. 54060-30-9. Pack Sizes: 10mg, 100mg, 1g, 5g. Molecular Formula: C8H7N, Form: Brown Oil. US Biological Life Sciences.
4-Decyn-1-ol is an intermediate in the synthesis of (Z)-4-decenyl acetate, sex pheromone of Batrachedra amydraula (Lesser date moth). Group: Pheromone ingredients. Alternative Names: 4-Decynol - Dec-4-yn-1-ol - 4-Decyne-1-ol - 1-Pentyl-2-(3-hydroxypropyl)acetylene. CAS No. 69222-06-6. Molecular formula: C10H18O. Mole weight: 154.25. Appearance: Clear, colourless to pale yellow liquid. Purity: 95.0% minimum. Catalog: ACM69222066.
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