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This bacterial enzyme is involved in the 7-dehydroxylation process associated with bile acid degradation. The enzyme has very little activity with unconjugated bile acid substrates. It has similar activity with choloyl-CoA, chenodeoxycholoyl-CoA, deoxycholoyl-CoA, and lithocholoyl-CoA. Group: Enzymes. Synonyms: baiA1 (gene name); baiA2 (gene name); baiA3 (gene name). Enzyme Commission Number: EC 1.1.1.395. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0315; 3α-hydroxy bile acid-CoA-ester 3-dehydrogenase; EC 1.1.1.395; baiA1 (gene name); baiA2 (gene name); baiA3 (gene name). Cat No: EXWM-0315.
3-hydroxy aciddehydrogenase
The enzyme, purified from the bacterium Escherichia coli and the yeast Saccharomyces cerevisiae, shows activity with a range of 3- and 4-carbon 3-hydroxy acids. The highest activity is seen with L-allo-threonine and D-threonine. The enzyme from Escherichia coli also shows high activity with L-serine, D-serine, (S)-3-hydroxy-2-methylpropanoate and (R)-3-hydroxy-2-methylpropanoate. The enzyme has no activity with NAD+ or L-threonine (cf. EC 1.1.1.103, L-threonine 3-dehydrogenase). Group: Enzymes. Synonyms: ydfG (gene name); YMR226c (gene name). Enzyme Commission Number: EC 1.1.1.381. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0300; 3-hydroxy aciddehydrogenase; EC 1.1.1.381; ydfG (gene name); YMR226c (gene name). Cat No: EXWM-0300.
D-2-hydroxyaciddehydrogenase (NAD+)
The enzymes, characterized from bacteria (Peptoclostridium difficile, Enterococcus faecalis and from lactic acid bacteria) prefer substrates with a main chain of 5 carbons (such as 4-methyl-2-oxopentanoate) to those with a shorter chain. It also utilizes phenylpyruvate. The enzyme from the halophilic archaeon Haloferax mediterranei prefers substrates with a main chain of 3-4 carbons (pyruvate and 2-oxobutanoate). cf. EC 1.1.1.272, (D)-2-hydroxyaciddehydrogenase (NADP+). Group: Enzymes. Synonyms: LdhA; HdhD; D-2-hydroxyisocaproate dehydrogenase; R-HicDH; D-HicDH; (R)-2-hydroxy-4-methylpentanoate:NAD+ oxidoreductase; (R)-2-hydroxyisocaproate dehydrogenase; D-mandelate dehydrogenase (ambiguous). Enzyme Commission Number: EC 1.1.1.345. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0260; D-2-hydroxyaciddehydrogenase (NAD+); EC 1.1.1.345; LdhA; HdhD; D-2-hydroxyisocaproate dehydrogenase; R-HicDH; D-HicDH; (R)-2-hydroxy-4-methylpentanoate:NAD+ oxidoreductase; (R)-2-hydroxyisocaproate dehydrogenase; D-mandelate dehydrogenase (ambiguous). Cat No: EXWM-0260.
D-2-hydroxyaciddehydrogenase (NADP+)
This enzyme, characterized from the halophilic archaeon Haloferax mediterranei and the mold Aspergillus oryzae, catalyses a stereospecific reduction of 2-oxocarboxylic acids into the corresponding D-2-hydroxycarboxylic acids. The enzyme prefers substrates with a main chain of 5 carbons (such as 4-methyl-2-oxopentanoate) to those with a shorter chain, and can use NADH with much lower efficiency. cf. EC 1.1.1.345, (D)-2-hydroxyaciddehydrogenase (NAD+). Group: Enzymes. Synonyms: ddh (gene name). Enzyme Commission Number: EC 1.1.1.272. CAS No. 81210-65-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0179; D-2-hydroxyaciddehydrogenase (NADP+); EC 1.1.1.272; 81210-65-3; ddh (gene name). Cat No: EXWM-0179.
D-2-hydroxyaciddehydrogenase (quinone)
The enzyme from mammalian kidney contains one mole of FAD per mole of enzyme.(R)-lactate, (R)-malate and meso-tartrate are good substrates. Ubiquinone-1 and the dye 2,6-dichloroindophenol can act as acceptors; NAD+ and NADP+ are not acceptors. Group: Enzymes. Synonyms: (R)-2-hydroxy aciddehydrogenase; (R)-2-hydroxy-acid:(acceptor) 2-oxidoreductase; D-lactate dehydrogenase (ambiguous). Enzyme Commission Number: EC 1.1.5.10. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0428; D-2-hydroxyaciddehydrogenase (quinone); EC 1.1.5.10; (R)-2-hydroxy aciddehydrogenase; (R)-2-hydroxy-acid:(acceptor) 2-oxidoreductase; D-lactate dehydrogenase (ambiguous). Cat No: EXWM-0428.
D-2-Hydroxyglutarate Dehydrogenase from Acidaminococcus fermentans, Recombinant
D-2-hydroxyglutarate (D2HG) level is significantly increased in metabolic diseases and various cancers such as acute myeloid leukemia. Studies suggest that the detection of D2HG serves as a biomarker assay related to IDH (isocitrate dehydrogenase) mutations. D2HGDH is a special NAD-dependent enzyme which reacts with D2HG specifically and converts D2HG to α-ketoglutarate. D2HGDH is a key enzyme to distinguish between two metabolites, D2HG and L-2-hydroxyglutarate (L2HG), during biomarker assays. Group: Enzymes. Synonyms: D-2-hydroxyglutarate dehydrogenase; D2HGDH; D2HGD. Enzyme Commission Number: EC 1.1.99.39. Purity: > 99% by SDS - PAGE. Mole weight: 39 kDa. Activity: > 90,000 mU/mg. Storage: Can be stored at 4°C up to 2 weeks. For long term storage, aliquot and store at -20°C. Avoid repeated freezing and thawing cycles. Form: Lyophilized in 50mM Tris, pH 8 without any additives. Source: E. coli. Species: Acidaminococcus fermentans. D-2-hydroxyglutarate dehydrogenase; D2HGDH; D2HGD. Cat No: NATE-1660.
This product with the indicated enzyme activity was briefly purified from engineered E. coli. Group: Enzymes. Enzyme Commission Number: EC 1.1.1.x. Activity: Undetermined. Appearance: Clear to translucent yellow solution. Storage: at -20 °C or lower, for at least 1 month. Source: E. coli. Hydroxyisocaproic AcidDehydrogenase. Pack: 100ml. Cat No: NATE-1798.
D-amino AcidDehydrogenase
synthesis of D-amino acids from ketoacids. Group: Enzymes. Synonyms: D-amino AcidDehydrogenase; D-AADH. Form: 1. Enzyme Powder: 17 items*50mg / item, or other quantity2. Screening Kit: 17 items*1mg / item. D-amino AcidDehydrogenase; D-AADH; Screening Kit; library of enzyme; enzyme library. Cat No: ENLC-012.
D-amino aciddehydrogenase (quinone)
An iron-sulfur flavoprotein (FAD). The enzyme from the bacterium Helicobacter pylori is highly specific for D-proline, while the enzyme from the bacterium Escherichia coli B is most active with D-alanine, D-phenylalanine and D-methionine. This enzyme may be the same as EC 1.4.99.6. Group: Enzymes. Synonyms: DadA. Enzyme Commission Number: EC 1.4.5.1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1486; D-amino aciddehydrogenase (quinone); EC 1.4.5.1; DadA. Cat No: EXWM-1486.
D-Amino aciddehydrogenase, Recombinant
D-amino-aciddehydrogenase (EC 1.4.99.1) is a bacterial enzyme that catalyses the oxidation of D-amino acids into their corresponding oxoacids. It contains both flavin and nonheme iron as cofactors. The enzyme has a very broad specificity and can act on most D-amino acids. D-amino acid + H2O + acceptor <=> a 2-oxo acid + NH3 + reduced acceptor. This reaction is distinct from the oxidation reaction catalysed by D-amino acid oxidase that uses oxygen as a second substrate, as the dehydrogenase can use many different compounds as electron acceptors, with the physiological substrate being coenzyme Q. D-amino-aciddehydrogenase is used in enzyme assays to measure substrate specificity of D-amino acids, such as DauA. Applications: D-amino-aciddehydrogenase is a bacterial enzyme that catalyses the oxidation of d-amino acids into their corresponding oxoacids. it contains flavin and nonheme iron as cofactors and has a broad specificity thereby acting on most d-amino acids. Group: Enzymes. Synonyms: D-Amino aciddehydrogenase; EC 1.4.99.1; 37205-44-0. Enzyme Commission Number: EC 1.4.99.1. CAS No. 37205-44-0. D-Amino aciddehydrogenase. Activity: >26 U/g. Storage: Store at 2-8°C. Source: E. coli. D-Amino aciddehydrogenase; EC 1.4.99.1; 37205-44-0. Cat No: NATE-0825.
A quinolinecarboxylic acid derivative with immunosuppressive and anti-neoplastic properties. Inhibits pyrimidine synthesis by blocking the activity of mammalian mitochondrial dihydroorotate dehydrogenase (DHODH; IC50 = 12nM). Does not affect DHODH in non-mammalian species. Also reported to inhibit glycosylation of adhesion molecules. Potentiates the sensitivity of U1690 small cell lung cancer cells to TRAIL-induced apoptosis and synergistically enhances the anti-tumor effects of doxorubicin ( ~100uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 96201-88-6. Pack Sizes: 10mg. Molecular Formula: C??H??F?NNaO?, Primary Target: DHODH. US Biological Life Sciences.
This product with the indicated enzyme activity was briefly purified from engineered E. coli. Applications: Synthesis. Group: Enzymes. Synonyms: (R)-sulfolactate:NAD + oxidoreductase; L-sulfolactate dehydrogenase; (R)-sulfolactate dehydrogenase; L-2-hydroxyaciddehydrogenase (NAD + ); ComC. Enzyme Commission Number: EC 1.1.1.337. CAS No. 81210-65-3. Activity: Undetermined. Appearance: Clear to translucent yellow solution. Storage: at -20 °C or lower, for at least 1 month. Source: E. coli. (R)-sulfolactate:NAD + oxidoreductase; L-sulfolactate dehydrogenase; (R)-sulfolactate dehydrogenase; L-2-hydroxyaciddehydrogenase (NAD + ); ComC. Pack: 100ml. Cat No: NATE-1797.
L-amino-aciddehydrogenase
Acts on aliphatic amino acids. Group: Enzymes. Enzyme Commission Number: EC 1.4.1.5. CAS No. 9029-13-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1460; L-amino-aciddehydrogenase; EC 1.4.1.5; 9029-13-4. Cat No: EXWM-1460.
(R)-2-hydroxy-fatty-aciddehydrogenase
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (R)-2-hydroxystearate:NAD+ oxidoreductase. Other names in common use include D-2-hydroxy fatty aciddehydrogenase, and 2-hydroxy fatty acid oxidase. Group: Enzymes. Synonyms: D-2-hydroxy fatty aciddehydrogenase; 2-hydroxy fatty acid oxidase. Enzyme Commission Number: EC 1.1.1.98. CAS No. 37250-32-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0382; (R)-2-hydroxy-fatty-aciddehydrogenase; EC 1.1.1.98; 37250-32-1; D-2-hydroxy fatty aciddehydrogenase; 2-hydroxy fatty acid oxidase. Cat No: EXWM-0382.
(R)-3-hydroxyacid-ester dehydrogenase
Also acts on ethyl (R)-3-oxobutanoate and some other (R)-3-hydroxy acid esters. The (R)- symbol is allotted on the assumption that no substituents change the order of priority from O-3 > C-2 > C-4. A subunit of yeast fatty acid synthase EC 2.3.1.86 fatty-acyl-CoA synthase). cf. EC 1.1.1.280 (S)-3-hydroxyacid ester dehydrogenase. Group: Enzymes. Synonyms: 3-oxo ester (R)-reductase. Enzyme Commission Number: EC 1.1.1.279. CAS No. 114705-02-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0186; (R)-3-hydroxyacid-ester dehydrogenase; EC 1.1.1.279; 114705-02-1; 3-oxo ester (R)-reductase. Cat No: EXWM-0186.
(S)-2-hydroxy-fatty-aciddehydrogenase
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (S)-2-hydroxystearate:NAD+ oxidoreductase. Other names in common use include dehydrogenase, L-2-hydroxy fatty acid, L-2-hydroxy fatty aciddehydrogenase, and 2-hydroxy fatty acid oxidase. Group: Enzymes. Synonyms: dehydrogenase, L-2-hydroxy fatty acid; L-2-hydroxy fatty aciddehydrogenase; 2-hydroxy fatty acid oxidase. Enzyme Commission Number: EC 1.1.1.99. CAS No. 37250-33-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0383; (S)-2-hydroxy-fatty-aciddehydrogenase; EC 1.1.1.99; 37250-33-2; dehydrogenase, L-2-hydroxy fatty acid; L-2-hydroxy fatty aciddehydrogenase; 2-hydroxy fatty acid oxidase. Cat No: EXWM-0383.
(S)-3-hydroxyacid-ester dehydrogenase
Also acts on 4-oxo- and 5-oxo-fatty acids and their esters. cf. EC 1.1.1.279 (R)-3-hydroxyacid-ester dehydrogenase. Group: Enzymes. Synonyms: 3-oxo ester (S)-reductase. Enzyme Commission Number: EC 1.1.1.280. CAS No. 114705-03-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0188; (S)-3-hydroxyacid-ester dehydrogenase; EC 1.1.1.280; 114705-03-2; 3-oxo ester (S)-reductase. Cat No: EXWM-0188.
The activity is part of a bifunctional enzyme also performing the reaction of EC 2.1.2.13 (UDP-4-amino-4-deoxy-L-arabinose formyltransferase). Group: Enzymes. Synonyms: UDP-GlcUA decarboxylase; ArnADH; UDP-glucuronate:NAD+ oxidoreductase (decarboxylating). Enzyme Commission Number: EC 1.1.1.305. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0216; UDP-glucuronic aciddehydrogenase (UDP-4-keto-hexauronic acid decarboxylating); EC 1.1.1.305; UDP-GlcUA decarboxylase; ArnADH; UDP-glucuronate:NAD+ oxidoreductase (decarboxylating). Cat No: EXWM-0216.
1, 1'-[ (2-Ethyl-1, 3-propanediyl) bis (oxymethylene) ]bisbenzene
1, 1'-[ (2-Ethyl-1, 3-propanediyl) bis (oxymethylene) ]bisbenzene is an intermediate in the synthesis of 2- (Hydroxymethyl) butanoic Acid (H946455), a substrate used to study the activity of 2-methyl-3hydroxybutyryl-CoA dehydrogenase deficiency in patients and carriers. Group: Biochemicals. Grades: Highly Purified. CAS No. 33498-90-7. Pack Sizes: 1g, 10g. Molecular Formula: C19H24O2. US Biological Life Sciences.
As an IMP dehydrogenase inhibitor, 1-(2,?3,?5-Tri-O-acetyl-β-D-ribofuranosyl)?-1,?2,?4-triazole-3-carboxylic Acid Methyl Ester is a reactant used in the synthesis of azole nucleoside 5'-MP mimics (P1Ms). Synonyms: Methyl 1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)?-1,2,4-triazole-3-carboxylate; 1-(2,3,5-Tri-O-acetyl-β-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxylic Acid Methyl Ester. Grades: 96%. CAS No. 39925-10-5. Molecular formula: C15H19N3O9. Mole weight: 385.33.
1-?(2,?3,?5-?Tri-?O-?acetyl-? β-?D-?ribofuranosyl)?-?1,?2,?4-?triazole-?3-?carboxylic Acid Methyl Ester is a reactant used in the synthesis of azole nucleoside 5'-?MP mimics (P1Ms) as IMP dehydrogenase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 39925-10-5. Pack Sizes: 10mg, 100mg. Molecular Formula: C15H19N3O9, Molecular Weight: 385.33. US Biological Life Sciences.
1-?(2,?3,?5-?Tri-?O-?acetyl-? β-?D-?ribofuranosyl)?-?1,?2,?4-?triazole-?3-?carboxylic Acid Methyl Ester-13C2 is the labeled analogue of 1-?(2,?3,?5-?Tri-?O-?acetyl-? β-?D-?ribofuranosyl)?-?1,?2,?4-?triazole-?3-?carboxylic Acid Methyl Ester (T767035), a reactant used in the synthesis of azole nucleoside 5'-?MP mimics (P1Ms) as IMP dehydrogenase inhibitors. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C1313C2H19N3O9, Molecular Weight: 387.31. US Biological Life Sciences.
Worldwide
12α-hydroxysteroid dehydrogenase
Catalyses the oxidation of the 12α-hydroxy group of bile acids, both in their free and conjugated form. Also acts on bile alcohols. Group: Enzymes. Synonyms: 12α-hydroxy steroid dehydrogenase; NAD+-dependent 12α-hydroxysteroid dehydrogenase; NADP+-12α-hydroxysteroid dehydrogenase. Enzyme Commission Number: EC 1.1.1.176. CAS No. 61642-40-8. 12α-Hydroxysteroid Dehydrogenase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0079; 12α-hydroxysteroid dehydrogenase; EC 1.1.1.176; 61642-40-8; 12α-hydroxy steroid dehydrogenase; NAD+-dependent 12α-hydroxysteroid dehydrogenase; NADP+-12α-hydroxysteroid dehydrogenase. Cat No: EXWM-0079.
12β-hydroxysteroid dehydrogenase
Acts on a number of bile acids, both in their free and conjugated forms. Group: Enzymes. Synonyms: 12β-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase. Enzyme Commission Number: EC 1.1.1.238. CAS No. 118390-62-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0145; 12β-hydroxysteroid dehydrogenase; EC 1.1.1.238; 118390-62-8; 12β-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase. Cat No: EXWM-0145.
15-hydroxyicosatetraenoate dehydrogenase
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate:NAD(P)+ 15-oxidoreductase. This enzyme is also called 15-hydroxyeicosatetraenoate dehydrogenase. This enzyme participates in arachidonic acid metabolism. Group: Enzymes. Synonyms: 15-hydroxyeicosatetraenoate dehydrogenase. Enzyme Commission Number: EC 1.1.1.232. CAS No. 117910-46-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0139; 15-hydroxyicosatetraenoate dehydrogenase; EC 1.1.1.232; 117910-46-0; 15-hydroxyeicosatetraenoate dehydrogenase. Cat No: EXWM-0139.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (1R,6R)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate:NAD+ oxidoreductase (decarboxylating). Other names in common use include 3,5-cyclohexadiene-1,2-diol-1-carboxylate dehydrogenase, 3,5-cyclohexadiene-1,2-diol-1-carboxylic aciddehydrogenase, dihydrodihydroxybenzoate dehydrogenase, DHBDH, cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase, 2-hydro-1,2-dihydroxybenzoate dehydrogenase, cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate:NAD+, oxidoreductase, and dihyd...Commission Number: EC 1.3.1.25. CAS No. 60496-16-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1299; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase; EC 1.3.1.25; 60496-16-4; 3,5-cyclohexadiene-1,2-diol-1-carboxylate dehydrogenase; 3,5-cyclohexadiene-1,2-diol-1-carboxylic aciddehydrogenase; dihydrodihydroxybenzoate dehydrogenase; DHBDH; cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase; 2-hydro-1,2-dihydroxybenzoate dehydrogenase; cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate:NAD+ oxidoreductase; dihydrodihydroxybenzoate dehydrogenase; (1R
1-Bromo-3,4-dimethoxy-2-propylbenzene
1-Bromo-3,4-dimethoxy-2-propylbenzene is an intermediate formed in the synthesis of 2,3-Dihydroxy-6-methyl-7-(phenylmethyl)-4-propyl-1-naphthalenecarboxylic Acid (D453265), which is used in the synthesis of novel lactate dehydrogenase A inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 142601-49-8. Pack Sizes: 100mg, 250mg. Molecular Formula: C11H15BrO2. US Biological Life Sciences.
Worldwide
1-Cyclopropane Mycophenolic Acid
1-Cyclopropane Mycophenolic Acid is a non-active analogue of Mycophenolic Acid (M831500), an antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. A selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase, an enzyme involved in the de novo synthesis of purine nucleotides. Group: Biochemicals. Grades: Highly Purified. CAS No. 125198-40-5. Pack Sizes: 10mg, 100mg. Molecular Formula: C18H22O6. US Biological Life Sciences.
Worldwide
1-deoxy-11β-hydroxypentalenate dehydrogenase
Isolated from the bacterium Streptomyces avermitilis and present in many other Streptomyces species. Part of the pathway for pentalenolactone biosynthesis. Group: Enzymes. Synonyms: 1-deoxy-11β-hydroxypentalenic aciddehydrogenase; ptlF (gene name); penF (gene name). Enzyme Commission Number: EC 1.1.1.340. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0255; 1-deoxy-11β-hydroxypentalenate dehydrogenase; EC 1.1.1.340; 1-deoxy-11β-hydroxypentalenic aciddehydrogenase; ptlF (gene name); penF (gene name). Cat No: EXWM-0255.
1H-Indazole-6-boronic Acid
It is commonly used in the preparation of reactants such as dicyclic hydroxybenzophenone derivatives as hydroxysteroid dehydrogenase inhibitors. Synonyms: 6-Indazolyboronic acid; 1H-Indazol-6-yl-6-boronic acid; (1H-indazol-6-yl)boronic acid; Indazole-6-boronic acid; Boronic acid, 1H-indazol-6-yl-; MFCD04972419; J-500188; (2H-indazol-6-yl)boronic acid; AMBA00083; CTK5G0023. Grades: > 97 % (HPLC). CAS No. 885068-10-0. Molecular formula: C7H7BN2O2. Mole weight: 161.95.
1-O-D-Sorbitol Mycophenolate
1-O-D-Sorbitol Mycophenolate is an impurity or sugar conjugate of Mycophenolic Acid (M831500), which is an antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. It is a selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C23H32O11, Molecular Weight: 484.49. US Biological Life Sciences.
(1R, 4R) -4-[[ (1, 1-Dimethylethoxy) carbonyl]amino]-2-cyclopentene-1-carboxylic Acid Methyl Ester is an intermediate in synthesizing trans-Abacavir Dihydrochloride (A104995), which is an impurity of Abacavir. Abacavir (A104990) is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Group: Biochemicals. Grades: Highly Purified. CAS No. 168958-19-8. Pack Sizes: 10mg, 25mg. Molecular Formula: C12H19NO4. US Biological Life Sciences.
Worldwide
20-Carboxy arachidonic acid
20-Carboxy arachidonic acid (20-COOH-AA) is the major metabolite of 20-HETE that is produced in renal tubular epithelial, endothelial, and microvascular smooth muscle cell cultures. This ω-oxidation conversion can take place using purified alcohol dehydrogenases three and four or by microsomes containing recombinant human CYP4F3B. Synonyms: 20-carboxy AA; 20-COOH-AA; 5Z,8Z,11Z,14Z-Eicosatetraenedioic acid; Arachidonic acid-20-carboxylic acid. Grades: >98%. CAS No. 79551-84-1. Molecular formula: C20H30O4. Mole weight: 334.5.
2-(3,5-Diformyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic Acid s an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C17H17NO5S, Molecular Weight: 347.39. US Biological Life Sciences.
2,3-Dihydroxy-6-methyl-7-(phenylmethyl)-4-propyl-1-naphthalenecarboxylic Acid-d5 is the labeled analogue of 2,3-Dihydroxy-6-methyl-7-(phenylmethyl)-4-propyl-1-naphthalenecarboxylic Acid (D453265), used in the synthesis of novel lactate dehydrogenase A inhibitors. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C22H17D5O4, Molecular Weight: 355.44. US Biological Life Sciences.
2,3-Dimethoxy-6-methyl-7-(phenylmethyl)-4-propyl-1-naphthalenecarboxylic Acid is an intermediate formed in the synthesis of 2,3-Dihydroxy-6-methyl-7-(phenylmethyl)-4-propyl-1-naphthalenecarboxylic Acid (D453265), which is used in the synthesis of novel lactate dehydrogenase A inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 213971-47-2. Pack Sizes: 5mg, 25mg. Molecular Formula: C24H26O4. US Biological Life Sciences.
2,3-Dimethoxy-7-methyl-6-(phenylmethyl)-1-propylnaphthalene is an intermediate formed in the synthesis of 2,3-Dihydroxy-6-methyl-7-(phenylmethyl)-4-propyl-1-naphthalenecarboxylic Acid, which is used in the synthesis of novel lactate dehydrogenase A inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 213971-42-7. Pack Sizes: 5mg, 25mg. Molecular Formula: C23H26O2. US Biological Life Sciences.
Worldwide
2,3-Xylohydroquinone
2,3-Xylohydroquinone is a useful synthetic intermediate. It was used in the synthesis of mycophenolic acid analogs with IMP dehydrogenase-inhibiting activities. It is a metabolite of butylamino (dimethylphenoxy) propanol, a new adrenergic β-blocking agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 608-43-5. Pack Sizes: 1g, 2.5g. Molecular Formula: C8H10O2. US Biological Life Sciences.
Worldwide
2,4-diaminopentanoate dehydrogenase
Also acts, more slowly, on 2,5-diaminohexanoate forming 2-amino-5-oxohexanoate, which then cyclizes non-enzymically to 1-pyrroline-2-methyl-5-carboxylate. Group: Enzymes. Synonyms: 2,4-diaminopentanoic acid C4 dehydrogenase. Enzyme Commission Number: EC 1.4.1.12. CAS No. 39346-26-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1445; 2,4-diaminopentanoate dehydrogenase; EC 1.4.1.12; 39346-26-4; 2,4-diaminopentanoic acid C4 dehydrogenase. Cat No: EXWM-1445.
2,4-Dichlorobenzeneboronic Acid
2,4-Dichlorobenzeneboronic Acid is an intermediate used to prepare N-hydroxyindole-2-carboxylates for use as lactate dehydrogenase inhibitors and Non-ATP competitive MK2 inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 68716-47-2. Pack Sizes: 1g, 5g. Molecular Formula: C6H5BCl2O2, Molecular Weight: 190.82. US Biological Life Sciences.
Worldwide
2,6-Dimethylheptanoyl-CoA Sodium Salt
2,6-Dimethylheptanoyl-CoA Sodium Salt is a sodium salt analog of 2,6-Dimethylheptanoyl-CoA , which is a specific substrate for long-chain acyl-CoA dehydrogenase (LCAD) which plays a major role in branched-chain fatty acid oxidation. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C30H52N7O17P3S; x(Na). US Biological Life Sciences.
Worldwide
2-Aminotetraline-2-carboxylic acid
2-Aminotetraline-2-carboxylic acid is a potent and selective IDH1 (isocitrate dehydrogenase 1) mutant inhibitor for the treatment of acute myeloid leukemia. Synonyms: Atc-OH; 2-Amino-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid; 2-Aminotetralin-2-carboxylic acid; D,L-2-Aminotetralin-2-carboxylic acid; 2-AMINOTETRALINE-2-CARBOXYLIC ACID; 2-Amino-1,2,3,4-tetrahydro-2-naphthalenecarboxylicacid; 2-amino-3,4-dihydro-1H-naphthalene-2-carboxylic acid; (R)-2-Amino-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid; (+/-)-2-Amino-1,2,3,4-tetrahydro-2-naphthoic acid; GSK 321; Atc OH. Grades: ≥ 98% (HPLC). CAS No. 6331-63-1. Molecular formula: C11H13NO2. Mole weight: 191.22.
2-Bromo-1,6-dimethyl Ester Hexanedioic Acid
2-Bromo-1,6-dimethyl Ester Hexanedioic Acid is an intermediate in the synthesis of 2-Hydroxyhexanedioic Acid Disodium Salt (H943015). Accumulation and excretion of 2-Hydroxyhexanedioic Acid (with 2-ketoadipic and 2-aminoadipic) in urine can be caused by 2-ketoadipic acidemia, probably without adverse phenotypic effects, due to deficiency of 2-ketoadipic dehydrogenase. Group: Biochemicals. Grades: Highly Purified. CAS No. 3196-19-8. Pack Sizes: 100mg, 250mg. Molecular Formula: C8H13BrO4. US Biological Life Sciences.
Worldwide
2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase
The enzyme from Pseudomonas acts equally well on NAD+ or NADP+, while that from Erwinia chrysanthemi and Escherichia coli is more specific for NAD+. Group: Enzymes. Synonyms: 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxy-D-gluconate dehydrogenase; 2-keto-3-deoxygluconate (nicotinamide adenine dinucleotide (phosphate)) dehydrogenase; 2-keto-3-deoxy-D-gluconate (3-deoxy-D-glycero-2,5-hexodiulosonic acid) dehydrogenase. Enzyme Commission Number: EC 1.1.1.127. CAS No. 37250-56-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0031; 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase; EC 1.1.1.127; 37250-56-9; 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxy-D-gluconate dehydrogenase; 2-keto-3-deoxygluconate (nicotinamide adenine dinucleotide (phosphate)) dehydrogenase; 2-keto-3-deoxy-D-gluconate (3-deoxy-D-glycero-2,5-hexodiulosonic acid) dehydrogenase. Cat No: EXWM-0031.
2-Ethyl-1,3-propanediol-d5
2-Ethyl-1,3-propanediol-d5 is a labelled analogue of 2-Ethyl-1,3-propanediol (E678665), which is an intermediate in the synthesis of Peloruside A related compounds, novel anti mitotic agents with Paclitaxel (P132500)-like microtubule-stabilizing activity. 2-Ethyl-1,3-propanediol-d5 is also an intermediate in synthesizing 2- (Hydroxymethyl) butanoic-d5 Acid (H946457), which is used as a substrate to study the activity of 2-methyl-3hydroxybutyryl-CoA dehydrogenase deficiency in patients and carriers. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C5H7D5O2. US Biological Life Sciences.
Worldwide
2-Fluoro-3-Methoxyphenylboronic acid
2-Fluoro-3-methoxyphenylboronic acid was used as the reactant to participate in the regional selective suzuki coupling, the preparation of 17 hydroxysteroid dehydrogenase type 1 inhibitors, and the preparation of boron esters. Synonyms: 2-fluoro-3-methoxybenzeneboronic acid; Boronic acid, (2-fluoro-3-methoxyphenyl)-; MFCD02094728; 2-fluoro-3-methoxy-phenyl-boronic acid; AK-34813; BC000799. Grades: 98 % (HPLC). CAS No. 352303-67-4. Molecular formula: C7H8BFO3. Mole weight: 169.95.
2-Hydroxy-4-(methylthio)butyric acid
2-Hydroxy-4-(methylthio)butyric acid is a dietary essential amino acid which is converted to Methionine (HY-13694) by 2-hydroxy aciddehydrogenase and 2-hydroxy acid oxidase. 2-Hydroxy-4-(methylthio)butyric acid is promising for research of gut disease [1]. Uses: Scientific research. Group: Natural products. CAS No. 583-91-5. Pack Sizes: 10 mM * 1 mL; 10 g; 25 g; 50 g. Product ID: HY-116688.
2-Hydroxyhexanedioic Acid Disodium Salt
Accumulation and excretion of 2-Hydroxyhexanedioic Acid (with 2-ketoadipic and 2-aminoadipic) in urine can be caused by 2-ketoadipic acidemia, probably without adverse phenotypic effects , due to deficiency of 2-ketoadipic dehydrogenase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg, 500mg. Molecular Formula: C6H8Na2O5. US Biological Life Sciences.
Worldwide
2-Ketobutyric Acid
A substrate for the determination of lactate dehydrogenase isoenzymes.This compound is suitable for lactate dehydrogenase (LDH) related research. Group: Biochemicals. Alternative Names: 2-Oxobutanoic Acid; 2-Oxobutyric Acid; 2-Ketobutanoic Acid; 2-Ketobutyric Acid; 2-Oxo-n-butyric Acid; 2-Oxobutanoic Acid; 2-Oxobutyric Acid; 3-Methylpyruvic Acid; NSC 60533; Propionylformic Acid; α-Ketobutyric Acid; α-Oxo-n-butyric Acid; α-Oxobutanoic Acid; α-Oxobutyric Acid; α-keto-n-Butyric Acid. Grades: Reagent Grade. CAS No. 600-18-0. Pack Sizes: 5g, 10g, 25g. US Biological Life Sciences.
Worldwide
2-Ketoglutaric Acid-d2 Cacium Salt (d3 major)
2-Ketoglutaric Acid-d2 Cacium Salt is a isotope labelled derivative of glutaric acid and is an intermediate in the krebs cycle catalyzed by glutamate dehydrogenase enzyme on glutamate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 25mg. Molecular Formula: C5H2D2CaO5. US Biological Life Sciences.
Worldwide
2-NH2-6-Cl-5'-PuMP
2-NH2-6-Cl-5'-PuMP is an analogue of guanosine-5'-O-monophosphate and an inhibitor of IMP dehydrogenase. It is often used as the precursor for 6-modified 5'-GMP derivatives. Synonyms: 2-Amino-6-chloropurine riboside-5'-O-monophosphate, sodium salt. Grades: ≥ 97% by HPLC. CAS No. 16321-98-5. Molecular formula: C10H13ClN5O7P (free acid). Mole weight: 381.67.
2-[ (Phenylmethoxy)methyl]-1-butanol
2-[ (Phenylmethoxy)methyl]-1-butanol is an intermediate in the synthesis of 2- (Hydroxymethyl) butanoic Acid (H946455), a substrate used to study the activity of 2-methyl-3hydroxybutyryl-CoA dehydrogenase deficiency in patients and carriers. Group: Biochemicals. Grades: Highly Purified. CAS No. 14058-59-4. Pack Sizes: 25mg, 250mg. Molecular Formula: C12H18O2. US Biological Life Sciences.
Worldwide
2-[ (Phenylmethoxy) methyl]butanoic Acid
2-[ (Phenylmethoxy) methyl]butanoic Acid is an intermediate in the synthesis of 2- (Hydroxymethyl) butanoic Acid (H946455), a substrate used to study the activity of 2-methyl-3hydroxybutyryl-CoA dehydrogenase deficiency in patients and carriers. Group: Biochemicals. Grades: Highly Purified. CAS No. 1598357-06-2. Pack Sizes: 10mg, 100mg. Molecular Formula: C12H16O3. US Biological Life Sciences.
Worldwide
(2R,3S)-3-Methylmalic Acid
(2R,3S)-3-Methylmalic Acid is used as one of determinants of performance in isocitrate dehydrogenase of Escherichia coli. Group: Biochemicals. Grades: Highly Purified. CAS No. 152204-30-3. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C5H8O5, Molecular Weight: 148.11. US Biological Life Sciences.
3-[[[3-[4-[ (Methylsulfonyl) amino]phenyl]-4-oxo-4H-chromen-7-yl]oxy]methyl]benzoic Acid is a highly selective reversible aldehyde dehydrogenase 2 (ALDH-2) inhibitor that reduce alcohol and cocaine intake in rats. It also has anxiolytic properties as well as reduces excessive alcohol drinking. Group: Biochemicals. Grades: Highly Purified. CAS No. 1005334-57-5. Pack Sizes: 1mg, 5mg. Molecular Formula: C24H19NO7S, Molecular Weight: 465.48. US Biological Life Sciences.
Worldwide
3-Acetylpyridine-adenine dinucleotide phosphate, reduced form, tetrasodium salt (APADPH)
Molecular Formula: C22H32N6O17P3. Group: Coenzymes. Synonyms: APADPH. Enzyme Commission Number: EC 1.1.1.1. Purity: > 92% when determined by enzymatic analysis with glutamate dehydrogenase at pH 7.5. APADPH. Mole weight: 745.45 (as anhydrous free acid) 886.41 (APADPH.Na4.3H2O). Storage: Keep tightly stoppered in the dark below 5°C. Moisture will accelerate the purity reduction. For prolonged storage keep below - 20°C. APADPH. Cat No: NATE-0080.
3α(17β)-hydroxysteroid dehydrogenase (NAD+)
Also acts on other 17β-hydroxysteroids and on the 3α-hydroxy group of pregnanes and bile acids. Different from EC 1.1.1.50 3α-hydroxysteroid dehydrogenase (Si-specific) or EC 1.1.1.213 3α-hydroxysteroid dehydrogenase (Re-specific). Group: Enzymes. Synonyms: 3α,17β-hydroxy steroid dehydrogenase; 3α(17β)-HSD; 17-ketoreductase (ambiguous); 17β-HSD (ambiguous); HSD17B6 (gene name); HSD17B8 (gene name). Enzyme Commission Number: EC 1.1.1.239. CAS No. 126469-82-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0146; 3α(17β)-hydroxysteroid dehydrogenase (NAD+); EC 1.1.1.239; 126469-82-7; 3α,17β-hydroxy steroid dehydrogenase; 3α(17β)-HSD; 17-ketoreductase (ambiguous); 17β-HSD (ambiguous); HSD17B6 (gene name); HSD17B8 (gene name). Cat No: EXWM-0146.
This enzyme forms part of the rat peroxisomal multifunctional enzyme perMFE-2, which also exhibits a dehydrogenase activity. The enzyme is involved in the β-oxidation of the cholesterol side chain in the cholic-acid-biosynthesis pathway. Group: Enzymes. Synonyms: 46 kDa hydratase 2; (24R,25R)-3α,7α,12α,24-tetrahydroxy-5β-cholestanoyl-CoA hydro-lyase. Enzyme Commission Number: EC 4.2.1.107. CAS No. 152787-68-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4946; 3α,7α,12α-trihydroxy-5β-cholest-24-enoyl-CoA hydratase; EC 4.2.1.107; 152787-68-3; 46 kDa hydratase 2; (24R,25R)-3α,7α,12α,24-tetrahydroxy-5β-cholestanoyl-CoA hydro-lyase. Cat No: EXWM-4946.
3α-hydroxycholanate dehydrogenase (NAD+)
Also acts on other 3α-hydroxysteroids with an acidic side-chain. cf. EC 1.1.1.392, 3α-hydroxycholanate dehydrogenase (NADP+). Group: Enzymes. Synonyms: α-hydroxy-cholanate dehydrogenase; lithocholate:NAD+ oxidoreductase; 3α-hydroxycholanate dehydrogenase. Enzyme Commission Number: EC 1.1.1.52. CAS No. 9028-57-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0337; 3α-hydroxycholanate dehydrogenase (NAD+); EC 1.1.1.52; 9028-57-3; α-hydroxy-cholanate dehydrogenase; lithocholate:NAD+ oxidoreductase; 3α-hydroxycholanate dehydrogenase. Cat No: EXWM-0337.
3α-hydroxycholanate dehydrogenase (NADP+)
This bacterial enzyme is involved in the modification of secondary bile acids to form 3β-bile acids (also known as iso-bile acids) via a 3-oxo intermediate. The enzyme catalyses a reversible reaction in vitro. Also acts on related bile acids. cf. EC 1.1.1.52, 3α-hydroxycholanate dehydrogenase (NAD+). Group: Enzymes. Synonyms: α-hydroxy-cholanate dehydrogenase (ambiguous). Enzyme Commission Number: EC 1.1.1.392. CAS No. 9028-57-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0312; 3α-hydroxycholanate dehydrogenase (NADP+); EC 1.1.1.392; 9028-57-3; α-hydroxy-cholanate dehydrogenase (ambiguous). Cat No: EXWM-0312.
3α-Hydroxysteroid Dehydrogenase, Recombinant
In enzymology, a 3alpha-hydroxysteroid dehydrogenase (B-specific) (EC 1.1.1.50) is an enzyme that catalyzes the chemical reaction: androsterone + NAD (P)+ ? 5alpha-androstane-3,17-dione + NAD (P)H + H+. The 3 substRates of this enzyme are androsterone, NAD+, and NADP+, whereas its 4 products are 5alpha-androstane-3,17-dione, NADH, NADPH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor, more specifically it is part of the group of hydroxysteroid dehydrogenases. Applications: Bile acid is one of the substrates of 3α-hydroxy steroiddehydrogenase. 3α-hydroxy ste...3-dehydrogenase (B-specific); 3α-hydroxysteroid:NAD (P)+ 3-oxidoreductase (B-specific); EC 1.1.1.50. Enzyme Commission Number: EC 1.1.1.50. Purity: 90% (SDS-PAGE test). Mole weight: About 28 kDa (SDS-PAGE detection). Activity: About 50U/mg powder. Appearance: White powder, lyophilized. Storage: 4°C, store at -20°C for long-term preservation. Form: Freeze dried powder. hydroxyprostaglandin dehydrogenase; 3α-hydroxysteroid oxidoreductase; sterognost 3α; 3α-hydroxysteroid dehydrogenase (B-specific); 3α-hydroxysteroid 3-dehydrogenase (B-specific); 3α-hydroxysteroid:NAD (P)+ 3-oxidoreductase (B-specific); EC 1.1.1.50. Cat No: NATE-1138.
3-Amino-3-methylbutanoic Acid, 90%
3-Amino-3-methylbutanoic Acid acts as a reagent in the preparation of arylsulfonyl methylbutanamides of cycloalkylamines, particularly adamantylamines, as selective inhibitors of human and murine 11 β-hydroxysteroid dehydrogenase type 1. Synthesis of acetylcholine and carbamoylcholine analogs as a functionally selective α4 β2 nicotinic acetylcholine receptor agonist. Phenamide preparation by coupling reaction. Group: Biochemicals. Grades: Highly Purified. CAS No. 625-05-8. Pack Sizes: 250mg, 1g. Molecular Formula: C5H11NO2. US Biological Life Sciences.
3-(Aminocarbonyl)-1-(2,3,5-tri-O-acetyl- β-D-ribofuranosyl)-pyridinium-d4 Triflate is an intermediate in the synthesis of β-NADH-d5 (d5-major) Diammonium Salt (N201487). β-NADH-d4 is labelled β-NADH (N201480, Disodium salt). β-NADH is one of the biologically active forms of nicotinic acid. Serves as a coenzyme of hydrogenases and dehydrogenases. NAD usually acts as a hydrogen acceptor, forming NADH which then serves as a hydrogen donor in the respiratory chain. Present in living cells primarily in the reduced form (NADPH) and is involved in synthetic reactions. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C17H17D4N2O8+; CF3O3S-. US Biological Life Sciences.
Worldwide
3β-hydroxycholanate 3-dehydrogenase (NAD+)
This bacterial enzyme is involved, along with EC 1.1.1.52, 3α-hydroxycholanate dehydrogenase (NAD+), or EC 1.1.1.392, 3α-hydroxycholanate dehydrogenase (NADP+), in the modification of secondary bile acids to form 3β-bile acids (also known as iso-bile acids). The enzyme catalyses the reaction in the reduction direction in vivo. Also acts on related 3-oxo bile acids. cf. EC 1.1.1.393, 3β-hydroxycholanate 3-dehydrogenase (NADP+). Group: Enzymes. Synonyms: 3β-hydroxysteroid dehydrogenase. Enzyme Commission Number: EC 1.1.1.391. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0311; 3β-hydroxycholanate 3-dehydrogenase (NAD+); EC 1.1.1.391; 3β-hydroxysteroid dehydrogenase. Cat No: EXWM-0311.
3β-hydroxycholanate 3-dehydrogenase (NADP+)
This bacterial enzyme is involved, along with EC 1.1.1.52, 3α-hydroxycholanate dehydrogenase (NAD+), or EC 1.1.1.392, 3α-hydroxycholanate dehydrogenase (NADP+), in the modification of secondary bile acids to form 3β-bile acids (also known as iso-bile acids). The enzyme catalyses the reaction in the reduction direction in vivo. Also acts on related 3-oxo bile acids. cf. EC 1.1.1.391, 3β-hydroxycholanate 3-dehydrogenase (NAD+). Group: Enzymes. Synonyms: 3β-hydroxysteroid dehydrogenase (ambiguous). Enzyme Commission Number: EC 1.1.1.393. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0313; 3β-hydroxycholanate 3-dehydrogenase (NADP+); EC 1.1.1.393; 3β-hydroxysteroid dehydrogenase (ambiguous). Cat No: EXWM-0313.
3-Bicyclo[3.2.1]octanone
3-Bicyclo[3.2.1]octanone is used as a reactant in the synthesis of polycyclic acid derivatives as selective inhibitors of human 11 β-hydroxysteroid dehydrogenase type 1 (11 β-HSD-1). Group: Biochemicals. Grades: Highly Purified. CAS No. 14252-05-2. Pack Sizes: 250mg, 2.5g. Molecular Formula: C8H12O, Molecular Weight: 124.18. US Biological Life Sciences.
Worldwide
3-Bromobenzoic Acid Methyl Ester-d4
3-Bromobenzoic Acid Methyl Ester-d4, is the labeled analogue of 3-Bromobenzoic Acid Methyl Ester (B680250), an halogenated benzoate derivative used as a reagent in organic synthesis. 3-Bromobenzoic Acid Methyl Ester is used in the synthesis of a novel series of tetra hydrodibenzazocine as inhibitors of 17 β-hydroxysteroid dehydrogenase type 3. Group: Biochemicals. Grades: Highly Purified. CAS No. 1643575-37-4. Pack Sizes: 100mg, 500mg. Molecular Formula: , Molecular Weight: US Biological Life Sciences.
Worldwide
3-Butynoic acid
3-Butynoic acid is an inhibitor of acyl CoA dehydrogenase [1]. 3-Butynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Natural products. CAS No. 2345-51-9. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg; 1 g. Product ID: HY-W004784.
3-(Difluoromethyl)-1H-pyrazole-4-carboxylic Acid
3-(Difluoromethyl)-1H-pyrazole-4-carboxylic Acid is an intermediate in synthesizing Sedaxane (S242000), a broad-spectrum seed treatment fungicide used for control of seed- and soil-borne diseases in a broad range of crops. It inhibits fungal respiration by binding to the succinate dehydrogenase complex in the fungal mitochondrium. Group: Biochemicals. Grades: Highly Purified. CAS No. 151734-02-0. Pack Sizes: 2.5g, 5g. Molecular Formula: C6H6F2N2O2. US Biological Life Sciences.
Worldwide
3-hydroxyacyl-CoA dehydrogenase
Also oxidizes S-3-hydroxyacyl-N-acylthioethanolamine and S-3-hydroxyacyl-hydrolipoate. Some enzymes act, more slowly, with NADP+. Broad specificity to acyl chain-length (cf. EC 1.1.1.211 [long-chain-3-hydroxyacyl-CoA dehydrogenase]). Group: Enzymes. Synonyms: β-hydroxyacyl dehydrogenase; β-keto-reductase; 3-keto reductase; 3-hydroxyacyl coenzyme A dehydrogenase; β-hydroxyacyl-coenzyme A syn. Enzyme Commission Number: EC 1.1.1.35. CAS No. 9028-40-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0265; 3-hydroxyacyl-CoA dehydrogenase; EC 1.1.1.35; 9028-40-4; β-hydroxyacyl dehydrogenase; β-keto-reductase; 3-keto reductase; 3-hydroxyacyl coenzyme A dehydrogenase; β-hydroxyacyl-coenzyme A synthetase; β-hydroxyacylcoenzyme A dehydrogenase; β-hydroxybutyrylcoenzyme A dehydrogenase; 3-hydroxyacetyl-coenzyme A dehydrogenase; L-3-hydroxyacyl coenzyme A dehydrogenase; L-3-hydroxyacyl CoA dehydrogenase; β-hydroxyacyl CoA dehydrogenase; 3β-hydroxyacyl coenzyme A dehydrogenase; 3-hydroxybutyryl-CoA dehydrogenase; β-ketoacyl-CoA reductase; β-hydroxy aciddehydrogenase; 3-L-hydroxyacyl-CoA dehydrogenase; 3-hydroxyisobutyryl-CoA dehydrogenase; 1-specific DPN-linked β-hydroxybutyric dehydrogenase. Cat No: EXWM-0265.
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