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| Product | Description | |
|---|---|---|
| 3-deoxy-D-manno-octulosonic acid kinase | The enzyme phosphorylates the 4-OH position of Kdo in (Kdo)-lipid IVA. Group: Enzymes. Synonyms: kdkA (gene name); Kdo kinase. Enzyme Commission Number: EC 2.7.1.166. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2996; 3-deoxy-D-manno-octulosonic acid kinase; EC 2.7.1.166; kdkA (gene name); Kdo kinase. Cat No: EXWM-2996. |  |
| anhydro-N-acetylmuramic acid kinase | This enzyme, along with EC 4.2.1.126, N-acetylmuramic acid 6-phosphate etherase, is required for the utilization of anhydro-N-acetylmuramic acid in proteobacteria. The substrate is either imported from the medium or derived from the bacterium's own cell wall murein during cell wall recycling. The product N-acetylmuramate 6-phosphate is produced as a 7:1 mixture of the α- and β-anomers. Group: Enzymes. Synonyms: anhMurNAc kinase; AnmK. Enzyme Commission Number: EC 2.7.1.170. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3001; anhydro-N-acetylmuramic acid kinase; EC 2.7.1.170; anhMurNAc kinase; AnmK. Cat No: EXWM-3001. | |
| branched-chain-fatty-acid kinase | 3-Methylbutanoate, 2-methylbutanoate, pentanoate, butanoate and propanoate can also act as acceptors (cf. EC 2.7.2.7 butyrate kinase). Group: Enzymes. Synonyms: isobutyrate kinase. Enzyme Commission Number: EC 2.7.2.14. CAS No. 84177-54-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3172; branched-chain-fatty-acid kinase; EC 2.7.2.14; 84177-54-8; isobutyrate kinase. Cat No: EXWM-3172. | |
| Casein Kinase II Inhibitor VIII (4- (2- (4-Methoxybenzamido) thiazol-5-yl) benzoic acid, CK2 Inhibitor VIII, DYRK1B Inhibitor, Flt-3 Inhibitor VII) | A cell-permeable thiazolamide compound that acts as a potent, reversible, and ATP-competitive inhibitor against casein kinase-2/CK2 (IC50=32 and 46nM against CK2a and CK2a', respectively), as well as DYRK1B and FLt-3 (82% and 76% inhibition, respectively, at 30nM), while diplaying reduced or little potency toward other targets in a 70-kinase panel selectivity profile study. Shown to effectively block the proliferation of a variety of cancer cells (IC50=2.6, 1.6, and 2.4uM, in A549, HCT116, and MCF-7 cultures, respectively). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| SKI-I, Sphingosine Kinase Inhibitor (5-naphthalen-2-yl-2H-pyrazole-3-carboxylic acid (2-hydroxy-naphthalen-1-ylmethylene)-hydrazide) | Cell-permeable. SKI-I is a non-lipid pan-sphingosine kinase (SK) inhibitor that inhibits both SK1 and SK2 to suppress the production of pro-mitogenic sphingosine 1-phosphate (S1P) and promote cell death. Also induces autophagy. Group: Biochemicals. Grades: Highly Purified. CAS No. 306301-68-8. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| 1,1,1-Trifluoro-methanesulfonic Acid 3-[[ (1, 1-Dimethylethoxy) carbonyl]amino]-1-cyclohexen-1-yl Ester | 1,1,1-Trifluoro-methanesulfonic Acid 3-[[ (1, 1-Dimethylethoxy) carbonyl]amino]-1-cyclohexen-1-yl Ester is an intermediate in synthesizing tert-Butyl (3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-en-1-yl)carbamate (T302650), which is a reactant in the preparation of furo[3,2-c]pyridine derivatives as protein kinase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 1803033-60-4. Pack Sizes: 25mg, 50mg. Molecular Formula: C12H18F3NO5S. US Biological Life Sciences. | Worldwide |
| 1,1,1-Trifluoro-methanesulfonic Acid 5-[[ (1, 1-Dimethylethoxy) carbonyl]amino]-1-cyclohexen-1-yl Ester | 1,1,1-Trifluoro-methanesulfonic Acid 5-[[ (1, 1-Dimethylethoxy) carbonyl]amino]-1-cyclohexen-1-yl Ester is an intermediate in synthesizing tert-Butyl (3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-en-1-yl)carbamate (T302650), which is a reactant in the preparation of furo[3,2-c]pyridine derivatives as protein kinase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 1803033-59-1. Pack Sizes: 25mg, 50mg. Molecular Formula: C12H18F3NO5S. US Biological Life Sciences. | Worldwide |
| 1, 1, 1-Trifluoromethane sulfonic Acid (E) -4-[1-[4-[2- (Dimethylamino) ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenyl Ester | 1, 1, 1-Trifluoromethane sulfonic Acid (E) -4-[1-[4-[2- (Dimethylamino) ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenyl Ester is an impurity of Tamoxifen (T006000), a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1370699-80-1. Pack Sizes: 5mg, 25mg. Molecular Formula: C27H28F3NO4S. US Biological Life Sciences. | Worldwide |
| 1, 1, 1-Trifluoromethane sulfonic Acid Tris(1-methylethyl)silyl Ester | 1, 1, 1-Trifluoromethane sulfonic Acid Tris(1-methylethyl)silyl Ester is used in the synthesis of potent BRAF kinase inhibitors used in the therapeutic treatment of melanoma. Also used in the synthesis of antitumor antibiotic (+)-FR900482. Group: Biochemicals. Alternative Names: TIPSOTf; Triisopropyl (trifluoromethane sulfonato) silane ; Triisopropylsilyl Triflate; Triisopropylsilyl Trifluoromethane sulfonate. Grades: Highly Purified. CAS No. 80522-42-5. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| 1,1,1-Trimethoxybutane | 1,1,1-Trimethoxybutane is used in the synthesis of angiotensin II receptor antagonists affecting blood pressure. Also used in the preparation of inhibitors of cyclin-dependant kinases. Group: Biochemicals. Alternative Names: Trimethyl Ester Orthobutyric Acid; 1,1,1-Trimethoxybutane; Methyl Orthobutyrate; Trimethyl Orthobutanoate; Trimethyl Orthobutyrate. Grades: Highly Purified. CAS No. 43083-12-1. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| 1,2-Benzisoxazole-5-carboxylic Acid | 1,2-Benzisoxazole-5-carboxylic Acid is used as a reagent in the synthesis of pyrazolopyrimidinone compounds for the inhibition of PAS Kinase (PASK) activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 933744-95-7. Pack Sizes: 100mg, 1g. Molecular Formula: C8H5NO3, Molecular Weight: 163.13. US Biological Life Sciences. | Worldwide |
| 12-HETE | 12-HETE, a major metabolic product of arachidonic acid using 12-LOX catalysis, inhibits cell apoptosis in a dose-dependent manner. 12-HETE promotes the activation and nuclear translocation of NF-κB through the integrin-linked kinase (ILK) pathway [1].12-HETE has both anti-thrombotic and pro-thrombotic effects [2]. 12-HETE is a neuromodulator [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 71030-37-0. Pack Sizes: 50 μg (312.04 μM * 0.5 mL in Ethanol); 100 μg (312.04 μM * 1 mL in Ethanol). Product ID: HY-113439. |  |
| 1-(2-Methyl-5-nitrophenyl)guanidine Nitrate | Protein kinase inhibitors. Synonyms: 2-(2-methyl-5-nitrophenyl)guanidine;nitric acid; 2-(2-methyl-5-nitrophenyl)guanidine;nitric acid. Grades: > 95 %. CAS No. 152460-08-7. Molecular formula: C8H11N5O5. Mole weight: 257.20. |  |
| 12(S)-HpETE | 12(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of platelet or leukocyte 12-lipoxygenase (12-LO) on arachidonic acid. It mediates the inhibitory synaptic response to FMRF-amide in Aplysia sensory neurons6 and inhibits Ca2+/calmodulin-dependent protein kinase II from rat brain cortex. Synonyms: 12-Hydroperoxyicosatetraenoate; (5Z,8Z,10E,12S,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoic acid. Grades: ≥98%. CAS No. 71774-10-2. Molecular formula: C20H32O4. Mole weight: 336.5. | |
| 1,3-Dioleoyl-rac-glycerol | 1,3-Dioleoyl-rac-glycerol is a diacylglycerol that contains oleic acid at the sn-1 and sn-3 positions. It activates protein kinase C (PKC) by approximately 30% when used at a concentration of 50 μM. It was used in the synthesis of amphiphilic gadolinium complexes as MRI contrast agents. Synonyms: 2-Hydroxy-1,3-propanediyl dioleate; Glycerol 1,3-dioleate; 1,3-Diolein. Grades: ≥98%. CAS No. 2465-32-9. Molecular formula: C39H72O5. Mole weight: 620.99. | |
| 1,3-Dipalmitoyl-rac-glycerol | 1,3-Dipalmitoyl-rac-glycerol is a diacylglycerol that contains palmitic acid at the sn-1 and sn-3 positions. It activates protein kinase C α (PKCα) in vitro (Ka = 3.8 μM). 1,3-Dipalmitoyl-rac-glycerol (0.25-2 μM) inhibits apoptosis and production of reactive oxygen species (ROS) and pro-inflammatory mediators induced by oxygen-glucose deprivation and reperfusion (OGD/R) in SH-SY5Y neuroblastoma cells. An acyl acceptor for the unspecific bifunctional wax ester synthase/acyl-CoA:Diacylglycerol acyltransferase. Synonyms: 1,3-Dipalmitin; Dipalmitin; 1,3-Dipalmitoyl-glycerol; Glyceryl 1,3-dipalmitate. Grades: ≥98%. CAS No. 502-52-3. Molecular formula: C35H68O5. Mole weight: 568.91. | |
| (1α, 3α, 5α)-3, 5-dihydroxy-cyclohexanecarboxylic Acid Methyl Ester | (1α, 3α, 5α)-3, 5-dihydroxy-cyclohexanecarboxylic Acid Methyl Ester can be used as a starting material to synthesize pyrimido[4,5-d]pyrimidinones as selective inhibitors of both KDR and FGFR kinases. Group: Biochemicals. Grades: Highly Purified. CAS No. 156526-48-6. Pack Sizes: 500mg, 5g. Molecular Formula: C8H14O4, Molecular Weight: 174.19. US Biological Life Sciences. | Worldwide |
| 1-Benzyl -4-benzyl oxycarbonyl aminopiperidine | Intermediate used in the preparation p-38 kinase inhibitors and serotonin antagonists. Group: Biochemicals. Alternative Names: [1-(Phenylmethyl)-4-piperidinyl]carbamic Acid Phenylmethyl Ester; [1-(Benzyl)-4-piperidinyl]carbamic Acid Benzyl Ester; Benzyl (1-Benzylpiperidin-4-yl)carbamate; N-(Benzyloxycarbonyl)-1-benzylpiperidin-4-ylamine. Grades: Highly Purified. CAS No. 182223-53-6. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
| 1-Benzylindole-5-boronic Acid Pinacol Ester | 1-Benzylindole-5-boronic Acid Pinacol Ester acts as a reagent in the synthesis of 3,3-difluoro-2-oxindoles via electrophilic fluorination of indoles using N-fluoro Benzene sulfonimide. Preparation of triazolopyridine compounds as JAK kinase inhibitors useful in the treatment of neurodegenerative and inflammatory diseases. Group: Biochemicals. Grades: Highly Purified. CAS No. 1206163-56-5. Pack Sizes: 100mg, 250mg. Molecular Formula: C21H24BNO2, Molecular Weight: 333.23. US Biological Life Sciences. | Worldwide |
| 1-? (Benzyloxycarbonyl) ?pyrrolidine-?3-?carboxylic Acid | 1-? (Benzyloxycarbonyl) ?pyrrolidine-?3-?carboxylic Acid is a reagent used in the synthesis of cyclin-dependent kinase 4-inhibitors (CDK4) for cancer treatments. Also used towards the discovery of a potent inhibitor of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer pased upon benzimidazole carboxamide moieties. Group: Biochemicals. Grades: Highly Purified. CAS No. 188527-21-1. Pack Sizes: 100mg, 250mg. Molecular Formula: C13H15NO4, Molecular Weight: 249.26. US Biological Life Sciences. | Worldwide |
| 1-Boc-pyrazole-4-boronic Acid Pinacol Ester | 1-Boc-pyrazole-4-boronic Acid Pinacol Ester is used as a reagent in the synthesis of several inhibitors including thieno[3,2-c]pyridin-4-amines which are a novel series of Brutons tyrosine kinase (BTK) inhibitors which can be used in drug design. Group: Biochemicals. Grades: Highly Purified. CAS No. 552846-17-0. Pack Sizes: 1g, 2.5g. Molecular Formula: C14H23BN2O4, Molecular Weight: 294.149999999999. US Biological Life Sciences. | Worldwide |
| 1H-?Pyrazole-?3-?carboxaldehyde | 1H-?Pyrazole-?3-?carboxaldehyde is an intermediate used to prepare fused pyrrole carboxylic acids as novel, potent D-?amino acid oxidase (DAO) inhibitors. It is also a building block to synthesize α-?substituted benzylidene malononitrile tyrphostins as potent inhibitors of EGF receptor and ErbB2?/neu tyrosine kinases. Group: Biochemicals. Grades: Highly Purified. CAS No. 3920-50-1. Pack Sizes: 1g, 5 g. Molecular Formula: C4H4N2O, Molecular Weight: 96.09. US Biological Life Sciences. | Worldwide |
| 1H-Pyrrolo[3,2-b]pyridine-6-carboxylic Acid | 1H-Pyrrolo[3,2-b]pyridine-6-carboxylic Acid is an analog of 4-azaindole and can be used as a novel inhibitor of c-Met kinase. Group: Biochemicals. Grades: Highly Purified. CAS No. 112766-32-2. Pack Sizes: 100mg, 1 g. Molecular Formula: C8H6N2O2, Molecular Weight: 162.15. US Biological Life Sciences. | Worldwide |
| 1-Methyl-1H-indazole-6-carboxylic Acid Methyl Ester | 1-Methyl-1H-indazole-6-carboxylic Acid Methyl Ester is a useful synthetic intermediate. It is an analog of Indazole-3-carboxylic Acid Methyl Ester (I505250) which has potential as application of N-benzoylindazole derivatives and analogues as inhibitors of human neutrophil elastase. Indazole-3-carboxylic Acid Methyl Ester (I505250) is also used in the preparation of indazole-pyridine based protain kinase/Akt inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 1007219-73-9. Pack Sizes: 500mg, 5g. Molecular Formula: C10H10N2O2, Molecular Weight: 190.2. US Biological Life Sciences. | Worldwide |
| 1- methyl cyclohexanecarboxylic Acid | 1- methyl cyclohexanecarboxylic Acid is used in the synthesis of p38 map kinase. Group: Biochemicals. Alternative Names: 1-Methyl-1-cyclohexanecarboxylic Acid; 1- methyl cyclohexanecarboxylic Acid; 1- methyl cyclohexylcarboxylic Acid. Grades: Highly Purified. CAS No. 1123-25-7. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| 1- methyl cyclohexanecarboxylic Acid-d10 | Isotope labelled 1- methyl cyclohexanecarboxylic Acid is used in the synthesis of p38 map kinase. Group: Biochemicals. Alternative Names: 1-Methyl-1-cyclohexanecarboxylic Acid-d10; 1- methyl cyclohexanecarboxylic Acid-d10; 1- methyl cyclohexylcarboxylic Acid-d10. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 1-Oleoyl lysophosphatidic acid | 1-Oleoyl lysophosphatidic acid is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of phospholipase D (PLD) or through a two step process involving liberation of diacylglycerol (DAG) by phospholipase C (PLC) followed by phosphorylation of DAG by diglycerol kinase. Synonyms: 1-Oleoyl-sn-glycerol 3-phosphate; Oleoyl LPA; 18:1 LPA; 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate; LysoPA(18:1). Grades: ≥95%. CAS No. 65528-98-5. Molecular formula: C21H41O7P. Mole weight: 436.50. | |
| 1-Palmitoyl-d9-2-Palmitoyl-sn-glycerol | 1-Palmitoyl-d9-2-palmitoyl-sn-glycerol is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycerol by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycerol is a diacylglycerol that contains palmitic acid at the sn-1 and sn-2 positions. It activates protein kinase C (PKC) by 15% when used at a concentration of 25 μM. Synonyms: 1,2-Dipalmitoyl-sn-glycerol-d9; DG(16:0-d9/16:0/0:0). Grades: ≥99% atom D. CAS No. 1872379-48-0. Molecular formula: C35H59D9O5. Mole weight: 578. | |
| ((1R,3R)-3-Amino-cyclopentyl)-carbamic Acid tert-Butyl Ester | ((1R,3R)-3-Amino-cyclopentyl)-carbamic Acid tert-Butyl Ester is used in the preparation of quinoline-3-carboxoamides as H-PGDS inhibitors as well as novel triazolo-pyrrolopyridines as Janus kinase 1 inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 1009075-44-8. Pack Sizes: 5mg, 10mg. Molecular Formula: C10H20N2O2, Molecular Weight: 200.28. US Biological Life Sciences. | Worldwide |
| (1R, 3S) -3- [ (tert-Butoxycarbonyl) amino] cyclopentanecarboxylic Acid | (1R, 3S) -3- [ (tert-Butoxycarbonyl) amino] cyclopentanecarboxylic Acid is used as a reagent in the sunthesis of Jak1 kinase inhibitors stemming from tricyclic pyrrolopyrazines. Group: Biochemicals. Grades: Highly Purified. CAS No. 161660-94-2. Pack Sizes: 50mg, 100mg. Molecular Formula: C11H19NO4, Molecular Weight: 229.27. US Biological Life Sciences. | Worldwide |
| (1R) -N-Boc-1-[4- (hydroxymethyl) cyclohexyl]ethan-1-amine | Intermediate in the production of Rho kinase inhibitors and neurite outgrowth promoters. Group: Biochemicals. Alternative Names: (1R) -N- (tert-Butyloxycarbonyl) -1-[4- (hydroxymethyl) cyclohexyl]ethan-1-amine; [ (1R) -1- [4- (Hydroxymethyl) cyclohexyl] ethyl] carbamic Acid 1,1-Dimethylethyl Ester. Grades: Highly Purified. CAS No. 627314-62-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| (1R) -trans-4- [N-Boc-1-aminoethyl] cyclohexanecarboxylic Acid | Intermediate in the production of Rho kinase inhibitors and neurite outgrowth promoters. Group: Biochemicals. Alternative Names: trans-4- [ (1R) -1- [ [ (1, 1-Dimethylethoxy) carbonyl] amino] ethyl] cyclohexanecarboxylic Acid; trans-4- [ (R) -1- [ (tert-Butyloxycarbonyl) amino] ethyl] cyclohexanecarboxylic Acid. Grades: Highly Purified. CAS No. 671815-99-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| (1R)-trans-4-[N-Boc-1-aminoethyl]-N-4-pyridinyl-cyclohexanecarboxamide | Protected Y-27632, a Rho kinase inhibitor (ROCK) for the treatment of ischemia-reperfusion disorders. Group: Biochemicals. Alternative Names: [ (1R) -1- [trans-4- [ (4-Pyridinylamino) carbonyl] cyclohexyl] ethyl] carbamic Acid 1,1-Dimethylethyl Ester; N-Boc-Y-27632. Grades: Highly Purified. CAS No. 671816-04-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 20-Hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoic acid | 20-Hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoic acid is a potent vasoconstrictor produced in vascular smooth muscle cells. Its EC50 value is < 10 nM. It is a cytochrome P450 metabolite. It induces diuresis by inhibiting Na+-K+-ATPase in proximal tubules and Na+/K+/Cl+ cotransporter in the thick ascending limb of Henle's loop in kidney. It is involved in the regulation of sodium, potassium, and chloride transport in the renal tubules. It is a vasoconstrictor that mediates pressure-induced autoregulatory vasoconstriction in rat cerebral microvessels. It is excreted mainly as the glucuronide conjugate. It can be further metabolized by cyclooxygenase to 20-hydroxy PGG2 and 20-hydroxy PGH2. It regulates blood pressure in a complex way. It sensitizes smooth muscle cells to the constrictor stimuli and promotes the proliferation of endothelial cells. It has the ability to induce proinflammatory changes. It blocked the 70 pS K+ channel localized in the apical membrane in TALH cells. It was found to be a potent vasoconstrictor through activating the kinase pathways that contribute to the vascular tone regulation including MAPK, PKC, rho kinase and src-type tyrosine kinase. It may similarly regulate blood pressure and contribute to the development of stroke and heart attacks. Synonyms: 20-Hydroxyeicosatetraeonic acid; 20 Hydroxyeicosatetraeonic acid; 20Hydroxyeicosatetraeonic acid; 20HETE; 20 HETE; 20-HETE;(5Z,8Z,11Z,14Z)-20-hydroxyicosa-5,8,11,14-tetraenoic acid;20-Hydroxyeicosatetraenoic acid;20-hydroxy-5,8,11,14-eicosatetraenoic acid. Grades: >98%. CAS No. 79551-86-3. Molecular formula: C20H32O3. Mole weight: 320.47. | |
| 2-(1-Hexyn-1-yl)benzoic Acid | 2-(1-Hexyn-1-yl)benzoic Acid is an intermediate in synthesizing Apigenin 5-O- β-D-Glucuronide (A426510), a metabolite of Apigenin (A726500), Induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5 uM) by inhibiting MAP kinase activity. Also inhibits the proliferation of malignant tumor cells by G2/M arrest and induces morphological differentiation. Apigenin has also been reported to enhance the gap junction intracellular communication in liver cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 120870-47-5. Pack Sizes: 250mg, 500mg. Molecular Formula: C13H14O2. US Biological Life Sciences. | Worldwide |
| 2-(1-Methyl-2-oxoindolin-5-yl)-2-oxoacetic Acid | 2-(1-Methyl-2-oxoindolin-5-yl)-2-oxoacetic Acid is a derivative of 1-Methyl-2-indolone (M305490), a reactant for preparation of fluorescent analogues of strigolactones as affectors of parasitic weed germination and fungal branching, irreversible Nek2 Kinase Inhibitors and anticancer agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 1152495-80-1. Pack Sizes: 100mg, 1g. Molecular Formula: C11H9NO4, Molecular Weight: 219.19. US Biological Life Sciences. | Worldwide |
| 2-(1-Piperidino)aniline | 2-(1-Piperidino)aniline is used to prepare oxalylarylaminobenzoic acids as inhibitors of protein tyrosine phosphatase 1B. It is also used to synthesize benzimidazole derivatives as AMP-activated protein kinase activators. Group: Biochemicals. Grades: Highly Purified. CAS No. 39643-31-7. Pack Sizes: 100mg, 250mg. Molecular Formula: C11H16N2. US Biological Life Sciences. | Worldwide |
| 2,2-Dimethylcyclohexanone | 2,2-Dimethylcyclohexanone is a useful synthetic intermediate. It is used as a reagent to prepare 9-cis-retinoic acid ring-demethylated analogs. It is also used to prepare selective Janus kinase inhibitors for the treatment of autoimmune diseases and organ transplant rejection. Group: Biochemicals. Grades: Highly Purified. CAS No. 1193-47-1. Pack Sizes: 250mg, 1g. Molecular Formula: C8H14O. US Biological Life Sciences. | Worldwide |
| (2, 3, 4-Trimethoxyphenyl) boronic Acid | (2, 3, 4-Trimethoxyphenyl) boronic Acid is a reagent used in the synthesis of heteroaryl, mono and bicyclic compounds which may be used as inhibitors for EGF and PDGF receptor tyrosine kinases. Also used in the synthesis of non-steroidal CYP 17 inhibitors in the treatment of prostate cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 118062-05-8. Pack Sizes: 1g, 5g. Molecular Formula: C9H13BO5. US Biological Life Sciences. | Worldwide |
| 2,3,4-Tri-O-acetyl- β-D-glucuronic Acid Methyl Ester Propan-2-ol-D6 | 2,3,4-Tri-O-acetyl- β-D-glucuronic Acid Methyl Ester Propan-2-ol-D6 is an intermediate in the synthesis of Propylene Glycol-d6 1-Glucuronide (Mixture of Diastereomers) Sodium Salt (P835237). Isotope labelled Propylene Glycol 1-Glucuronide is a metabolite of propylene glycol, used in the synthesis of N-terminal kinase inhibitors with cellular activity. Acts as a solvent for various pharmaceutical compounds. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C16H18D6O11. US Biological Life Sciences. | Worldwide |
| 2-(3-Amino-4-chlorobenzoyl)benzoic Acid | 2-(3-Amino-4-chlorobenzoyl)benzoic Acid is used as a synthetic intermediate in the preparation of protein kinase C phosphorylates synthetic fluorescent reporter. Synonyms: 2-(3-Amino-4-chlorobenzoyl)benzoic acid; 118-04-7; Benzoic acid, 2-(3-amino-4-chlorobenzoyl)-; o-(3-Amino-4-chlorobenzoyl)benzoic acid; 2-(3-Amino-4-chlorobenzoyl)benzoic Acid); 2-(3'-Amino-4'-chlorobenzoyl)benzoic acid; Benzoic acid, o-(3-amino-4-chlorobenzoyl)-; 25WF7LMF9K; MFCD00007672; NSC-74496; 2-(3-Amino-4-chloro-benzoyl)benzoic acid; NSC74496; EINECS 204-230-4; NSC 74496; 2-(3-Amino-4-chlorobenzoyl)benzoioc acid; UNII-25WF7LMF9K; Oprea1_159790; SCHEMBL614963; DTXSID9059466; MQECGSWGDQIHHD-UHFFFAOYSA-N; AKOS000987621; 2-(3-Amino-4-chlorobenzoyl)benzoicacid; AC-15866; AS-12897; SY107325; 2-(3-Amino-4-chlorobenzoyl)benzoic acid #; Benzoic acid,2-(3-amino-4-chlorobenzoyl)-; CS-0156716; FT-0608536; O10462; SR-01000025110; SR-01000025110-1; W-108550; Z56754085. Grades: > 95%. CAS No. 118-04-7. Molecular formula: C14H10ClNO3. Mole weight: 275.69. | |
| 2-(3-Amino-4-chlorobenzoyl)benzoic Acid) | 2-(3-Amino-4-chlorobenzoyl)benzoic Acid is a useful synthetic intermediate. It is used to prepare protein kinase C phosphorylates synthetic fluorescent reporter. Group: Biochemicals. Grades: Highly Purified. CAS No. 118-04-7. Pack Sizes: 2.5g, 5g. Molecular Formula: C14H10ClNO3. US Biological Life Sciences. | Worldwide |
| 2,3-Dihydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylic Acid tert-Butyl Ester | Intermediate for the preparation of deazapurines, thienopyrimidines and furopyrimidines as phosphoinositide 3-kinase inhibitors useful in the treatment of diseases. Group: Biochemicals. Alternative Names: tert-Butyl 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)indoline-1-carboxylate; 2,3-Dihydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylic Acid 1,1-Dimethylethyl Ester. Grades: Highly Purified. CAS No. 1235451-62-3. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 2,3-O-Isopropylidene-L-ribono-1,4-lactone | 2,3-O-Isopropylidene-L-ribono-1,4-lactone, a versatile and imperative precursor compound, is widely utilized for synthesizing diverse carbohydrate-based therapeutics. It exerts immunomodulatory properties via the up-regulation of Itk kinase activity and is efficacious in treating myriad immune-related disorders, including autoimmunity and allergic diseases. Thus, it is a pivotal tool in the armamentarium of drug discovery and development. Synonyms: (3aS,6S,6aS)-6-(hydroxymethyl)-2,2-dimethyl-6,6a-dihydro-3aH-furo[3,4-d][1,3]dioxol-4-one; 2-O,3-O-Isopropylidene-L-ribonic acid 1,4-lactone; L-Ribonic acid, 2,3-O-(1-methylethylidene)-, γ-lactone; 2,3-O-Isopropylidene-L-ribonic acid-1,4-lactone. Grades: ≥95%. CAS No. 83085-15-8. Molecular formula: C8H12O5. Mole weight: 188.18. | |
| 2-(3-Phenyl-4,5-dihydroisoxazol-5-yl)acetic Acid | 2-(3-Phenyl-4,5-dihydroisoxazol-5-yl)acetic Acid reduces the secretion of IL-1 β, TNF-α and IL-10 from purified murine macrophages but not of T cells; and reduces the activation of NF-κB and p38 MAP kinase pathways along with up-regulation of ERK pathways. 2-(3-Phenyl-4,5-dihydroisoxazol-5-yl)acetic Acid inhibits proliferation of enterobacterial antigen-reactive CD4+CD25- T cells in vitro. Group: Biochemicals. Grades: Highly Purified. CAS No. 6501-72-0. Pack Sizes: 5mg, 10mg. Molecular Formula: C11H11NO3, Molecular Weight: 205.21. US Biological Life Sciences. | Worldwide |
| 2-(4-Boronophenyl)-2-methylpropanoic Acid | 2-(4-Boronophenyl)-2-methylpropanoic Acid is a reagent used in the synthesis of serum and glucocorticoid-related kinase 1 (SGK1) inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 1187209-18-2. Pack Sizes: 10mg, 25mg. Molecular Formula: C10H13BO4, Molecular Weight: 208.02. US Biological Life Sciences. | Worldwide |
| (2,4-Difluorophenoxy)acetic Acid Methyl Ester | (2,4-Difluorophenoxy)acetic Acid Methyl Ester is an intermediate in the synthesis of Pamapimod (P167500), a selective inhibitor of the α-isoform of p38 MAP kinase. Group: Biochemicals. Grades: Highly Purified. CAS No. 449811-63-6. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H8F2O3. US Biological Life Sciences. | Worldwide |
| 2-?(4-?Ethyl-?3-?iodophenyl)?-?2-?methylpropanoic Acid | 2-?(4-?Ethyl-?3-?iodophenyl)?-?2-?methylpropanoic Acid is an intermediate of Alectinib (C183360), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth. Group: Biochemicals. Grades: Highly Purified. CAS No. 1256584-73-2. Pack Sizes: 10mg, 50mg. Molecular Formula: C12H15IO2, Molecular Weight: 318.149999999999. US Biological Life Sciences. | Worldwide |
| 2-?(4-?Ethylphenyl)?-?2-?methylpropanoic Acid | 2-?(4-?Ethylphenyl)?-?2-?methylpropanoic Acid an intermediate of Alectinib (C183360), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth. Group: Biochemicals. Grades: Highly Purified. CAS No. 1247119-83-0. Pack Sizes: 25mg, 50mg. Molecular Formula: C12H16O2, Molecular Weight: 192.25. US Biological Life Sciences. | Worldwide |
| 2-(4-Methylpiperazin-1-ylmethyl)benzoic Acid | 2-(4-Methylpiperazin-1-ylmethyl)benzoic Acidis a reagent used in organic synthesis such as kinase inhibitors for hyperproliferative diseases. Group: Biochemicals. Grades: Highly Purified. CAS No. 514209-40-6. Pack Sizes: 100mg, 250mg. Molecular Formula: C13H18N2O2, Molecular Weight: 234.29. US Biological Life Sciences. | Worldwide |
| 2-((4R,6S)-6-((E)-2-(2-Cyclopropyl-4-phenylquinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic Acid tert-Butyl Ester | 2-((4R,6S)-6-((E)-2-(2-Cyclopropyl-4-phenylquinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic Acid tert-Butyl Ester is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Molecular formula: C32H37NO4. Mole weight: 499.64. | |
| 2,5-Dibromobenzoic Acid | 2,5-Dibromobenzoic Acid is an intermediate used to prepare benzo[c]chromenone and benzo[c]chromene derivatives as estrogen β-receptor-selective agonists in comparison with effusol and estradiol. It is also used in the synthesis of aminopyridine-based c-Jun N-terminal kinase inhibitors with cellular activity and minimal cross-kinase activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 610-71-9. Pack Sizes: 1g, 5g. Molecular Formula: C7H4Br2O2, Molecular Weight: 279.91. US Biological Life Sciences. | Worldwide |
| 2,7-Diazaspiro[3.5]nonane-7-carboxylic Acid tert-Butyl Ester | 2,7-Diazaspiro[3.5]nonane-7-carboxylic Acid tert-Butyl Ester is a reagent in the synthesis of RET kinase inhibitors. In addition it is used in the preparation of CDK4/6 inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 896464-16-7. Pack Sizes: 100mg, 250mg. Molecular Formula: C12H22N2O2, Molecular Weight: 226.32. US Biological Life Sciences. | Worldwide |
| 2-Acetamido-5-chloroisonicotinic Acid | 2-Acetamido-5-chloroisonicotinic Acid is a chemical reagent used in the synthesis of p38a protein kinase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 944390-08-3. Pack Sizes: 1g, 5g. Molecular Formula: C8H7ClN2O3, Molecular Weight: 214.61. US Biological Life Sciences. | Worldwide |
| 2-(Acetyloxy)-3-nitrobenzoic Acid Methyl Ester | 2-(Acetyloxy)-3-nitrobenzoic Acid Methyl Este is disubsituted benzoic acid derivative used in the preparation of various pharmaceutical compounds such as sphingosine kinase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 22621-42-7. Pack Sizes: 250mg, 500mg. Molecular Formula: C10H9NO6. US Biological Life Sciences. | Worldwide |
| 2-Amino-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-5-carboxylic Acid tert-Butyl Ester | 2-Amino-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-5-carboxylic Acid tert-Butyl Ester is a reagent used in the synthesis of 2-(thiazol-2-amino)-4-arylaminopyrimidines, which are anaplastic lymphoma kinase (ALK) inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 365996-05-0. Pack Sizes: 250mg, 500mg. Molecular Formula: C11H17N3O2S, Molecular Weight: 255.34. US Biological Life Sciences. | Worldwide |
| 2-Amino-4,5-bis(2-methoxyethoxy)benzoic Acid Ethyl Ester | 2-Amino-4,5-bis(2-methoxyethoxy)benzoic Acid Ethyl Ester is an intermediate in the synthesis of Erlotinib (E625000, HCl); a selective epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor and antineoplastic agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 179688-27-8. Pack Sizes: 250mg, 500mg. Molecular Formula: C15H23NO6, Molecular Weight: 313.35. US Biological Life Sciences. | Worldwide |
| 2-Amino-4-trifluoromethylbenzoic Acid Methyl Ester | 2-Amino-4-trifluoromethylbenzoic Acid Methyl Ester is an intermediate used to prepare quinazolinedione sulfonamides as competitive AMPA receptor antagonists. It is also used in the synthesis of (arylamino) pyrimidobenzazepinones and pyrimidobenzazepinethi ones as inhibitors of polo-like kinase 1 and potential antitumor agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 61500-87-6. Pack Sizes: 1g, 5g. Molecular Formula: C9H8F3NO2, Molecular Weight: 219.16. US Biological Life Sciences. | Worldwide |
| 2-Amino-5-thiazoleacetic Acid Ethyl Ester | 2-Amino-5-thiazoleacetic Acid Ethyl Ester is an intermediate used to synthesize thiazoloquinazoline derivatives as potent selective aurora A and B kinase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 62557-32-8. Pack Sizes: 100mg, 1g. Molecular Formula: C7H10N2O2S, Molecular Weight: 186.23. US Biological Life Sciences. | Worldwide |
| 2-Amino-5-(trifluoromethyl)-4-thiazolecarboxylic Acid | 2-Amino-5-(trifluoromethyl)-4-thiazolecarboxylic Acid is a derivative of 2-Aamino-4-thiazolecarboxylic Acid Ethyl Ester (E678465), a chemical reagent used in the preparation fo SAR thiazolamino arylaminopyrimidines as anaplastic lymphoma kinase inhibitors. As well as in the synthesis of 4-bicyclick piperadine derivatives as potent stearoyl-CoA desaturase (SCD1) inhibitors in the treatment of cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 1086380-23-5. Pack Sizes: 10mg, 100mg. Molecular Formula: C5H3F3N2O2S, Molecular Weight: 212.15. US Biological Life Sciences. | Worldwide |
| 2-Amino-6-bromo-3-fluoro-benzoic Acid | 2-Amino-6-bromo-3-fluoro-benzoic Acid is an intermediate used to prepare 2, 4-diaminopyrimidinyl aminoethyl quinazolin-4 (3H) -one derivatives as phosphatidylinositol 3-kinase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 1153974-98-1. Pack Sizes: 25mg, 50mg. Molecular Formula: C7H5BrFNO2, Molecular Weight: 234.02. US Biological Life Sciences. | Worldwide |
| 2-Aminopyridine-4-boronic Acid Pinacol Ester | 2-Aminopyridine-4-boronic Acid Pinacol Ester acts as a reagent in the preparation of indole- and 7-azaindolecarboxamides as Rho kinase inhibitors, 3D pharmacophore model-assisted discovery of novel heteroaryl dihydrothieno-pyridinones as CDC7 inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 1195995-72-2. Pack Sizes: 100mg, 250mg. Molecular Formula: C11H17BN2O2, Molecular Weight: 220.08. US Biological Life Sciences. | Worldwide |
| 2-Aminopyrimidine-5-boronic Acid Pinacol Ester | 2-Aminopyrimidine-5-boronic Acid Pinacol Ester is used in the preparation of phosphoinositide-3-kinases (PI3K) inhibitors. Group: Biochemicals. Alternative Names: (2-Aminopyrimidin-5-yl)boronic Acid Pinacol Ester; 2-(2-Aminopyrimidin-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2-amine; [5-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)pyrimidin-2-yl]amine. Grades: Highly Purified. CAS No. 402960-38-7. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| 2- ( ( (Benzyloxy) carbonyl) amino) -3- ( (diphenoxyphosphoryl) oxy) propanoic Acid Benzyl Ester-13C,15N | Isotope labelled 2- ( ( (Benzyloxy) carbonyl) amino) -3- ( (diphenoxyphosphoryl) oxy) propanoic Acid Benzyl Ester is an intermediate in the synthesis of L-O-Phosphoserine (P361202), the catalytic domain of human protein kinase C β II when complexed with a malemide inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 5mg. Molecular Formula: C2713C3H2815NO8P, Molecular Weight: 565.49. US Biological Life Sciences. | Worldwide |
| 2-Benzyloxyphenylboronic Acid | Reagent used in the preparation of different kinase inhibitors. Group: Biochemicals. Alternative Names: [2-[ (Phenylmethyl) oxy]phenyl]boronic Acid; B-[2- (Phenylmethoxy) phenyl]boronic Acid; 2- (Phenylmethoxy) benzeneboronic Acid. Grades: Highly Purified. CAS No. 190661-29-1. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| (2-Chloro-4-cyanophenyl)boronic Acid | (2-Chloro-4-cyanophenyl)boronic Acid is an intermediate used to prepare fused imidazole derivatives as TTK kinase inhibitors. It is also used in the synthesis of pyrimidothiophenes as HSP90 inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 677743-50-9. Pack Sizes: 100mg, 500mg. Molecular Formula: C7H5BClNO2, Molecular Weight: 181.38. US Biological Life Sciences. | Worldwide |
| 2-Chloroisonicotinic Acid | 2-Chloroisonicotinic Acid is a derivative of Isonicotinic Acid (I821760) and is used as a reagent in the synthesis of (phenylmorpholinyl) pyrimidinones as selective and orally active glycogen synthase kinase-3 β inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 6313-54-8. Pack Sizes: 1g, 5 g. Molecular Formula: C6H4ClNO2, Molecular Weight: 157.55. US Biological Life Sciences. | Worldwide |
| 2-Chloromethylbenzoic Acid | 2-Chloromethylbenzoic Acid acts as a reagent for the synthesis of (azolyl) methyl) arylbenzamides as dual inhibitors of VEGFR-1/2 kinases. Group: Biochemicals. Grades: Highly Purified. CAS No. 85888-81-9. Pack Sizes: 500mg, 1g. Molecular Formula: C8H7ClO2, Molecular Weight: 170.59. US Biological Life Sciences. | Worldwide |
| (2-?Chlorophenyl)?acetic Acid Ethyl Ester | (2-?Chlorophenyl)?acetic Acid Ethyl Ester is used to prepare clotrimazole analogs with antimalarial activities. It is also used to prepare non-nucleoside adenosine kinase inhibitors of aminoaryl aryl ethynyl pyrimidines. Group: Biochemicals. Grades: Highly Purified. CAS No. 40061-54-9. Pack Sizes: 100mg, 1g. Molecular Formula: C10H11ClO2, Molecular Weight: 198.65. US Biological Life Sciences. | Worldwide |
| 2-Cyclopropyl-4-phenyl-3-quinolinecarboxylic Acid Methyl Ester | 2-Cyclopropyl-4-phenyl-3-quinolinecarboxylic Acid Methyl Ester is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Methyl 2-cyclopropyl-4-phenylquinoline-3-carboxylate; 2-Cyclopropyl-4-phenyl-3-quinolinecarboxylic Acid Methyl Ester; DTXSID00857071; AKOS022175172; SB72967; Methyl2-cyclopropyl-4-phenylquinoline-3-carboxylate. CAS No. 868536-53-2. Molecular formula: C20H17NO2. Mole weight: 303.35. | |
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