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2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid is an impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: 2-(4-hydroxyphenyl)-4-methyl-5-thiazolecarboxylic acid; 2-(4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic acid. CAS No. 886501-78-6. Molecular formula: C11H9NO3S. Mole weight: 235.26.
3-Acetylpyridine-adenine dinucleotide phosphate, reduced form, tetrasodium salt (APADPH)
Molecular Formula: C22H32N6O17P3. Group: Coenzymes. Synonyms: APADPH. Enzyme Commission Number: EC 1.1.1.1. Purity: > 92% when determined by enzymatic analysis with glutamate dehydrogenase at pH 7.5. APADPH. Mole weight: 745.45 (as anhydrous free acid) 886.41 (APADPH.Na4.3H2O). Storage: Keep tightly stoppered in the dark below 5°C. Moisture will accelerate the purity reduction. For prolonged storage keep below - 20°C. APADPH. Cat No: NATE-0080.
Adenosine A2A Receptor Agonist I, Hydrochloride (CGS 21680)
A xanthin derivative that acts as a potent agonist of adenosine A2A receptors (Ki = 27nM). Exhibits reduced affinity for A2B receptors (Ki = 67nM), but offers greater selectivity over A1R (Ki = 290nM) and A3R (88.8uM). Exerts an anti-inflammatory effect during chronic inflammation and ameliorates the tissue damage associated with collagen-induced arthritis. Also shown to reduce CCR7 Protein Expression in THP1 macrophages. Shown to delay the progressive deterioration of motor performance and prevent a reduction in brain weight in murine model of Huntington's disease. Group: Biochemicals. Alternative Names: CGS-21680; 3- (4- (2- ( (6-amino-9- ( (2R, 3R, 4S, 5S) -5- (ethylcarbamoyl) -3, 4-di hydroxytetra hydrofuran-2-yl) -9H-purin-2-yl) amino) ethyl) phenyl) propanoic acid). Grades: Highly Purified. CAS No. 124182-57-6. Pack Sizes: 5mg. Molecular Formula: C23H29N7O6 HCl, Molecular Weight: 536. US Biological Life Sciences.
Worldwide
Atorvastatin EP Impurity F
Atorvastatin EP Impurity F is an impurity of Atorvastatin, which is an HMG-CoA reductase inhibitor used to reduce cholesterol and prevent cardiovascular-related disease. Synonyms: (3R,5R)-7-[[(3R,5R)-7-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoyl]amino]-3,5-dihydroxyheptanoic acid; Atorvastatin EP Impurity F; Atorvastatin calcium trihydrate impurity F [EP]; Heptanoic acid, 7-[[(3R,5R)-7-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-3,5-dihydroxy-1-oxoheptyl]amino]-3,5-dihydroxy-, (3R,5R)-; (3R,5R)-7-((3R,5R)-7-(2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanamido)-3,5-dihydroxyheptanoic acid; Atorvastatin diamino [USP impurity]; Atorvastatin amide. Grades: ≥95%. CAS No. 887196-24-9. Molecular formula: C40H48FN3O8. Mole weight: 717.82.
Atorvastatin EP Impurity G
Atorvastatin EP Impurity H is an impurity of Atorvastatin, which is an HMG-CoA reductase inhibitor used to reduce cholesterol and prevent cardiovascular-related disease. Synonyms: (3R,5R)-7-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-5-hydroxy-3-methoxyheptanoic acid; 3-O-Methylatorvastatin; Atorvastatin Impurity G; Atorvastatin calcium trihydrate impurity G [EP]; 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-δ-hydroxy-β-methoxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, (βR,δR)-; (βR,δR)-2-(4-Fluorophenyl)-δ-hydroxy-β-methoxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid; (3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-5-hydroxy-3-methoxyheptanoic acid. Grades: ≥95%. CAS No. 887324-53-0. Molecular formula: C34H37FN2O5. Mole weight: 572.67.
Atorvastatin USP Related Compound B
Atorvastatin USP Related Compound B is an impurity of Atorvastatin, which is an HMG-CoA reductase inhibitor used to reduce cholesterol and prevent cardiovascular-related disease. Synonyms: (3S,5R)-7-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid; (3S,5R)-Atorvastatin; Atorvastatin 3S,5R Isomer; 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, (βS,δR)-; (βS,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid. Grades: ≥95%. CAS No. 887324-52-9. Molecular formula: C33H35FN2O5. Mole weight: 558.64.
Boc-L-thyroxine
Boc-T4 is a synthetic prodrug of thyroxine, a hormone produced by the thyroid gland that plays a crucial role in regulating metabolism and other physiological processes. Boc-T4 is designed to be a prodrug that can be activated by enzymes in the body to release thyroxine slowly over a prolonged period. This approach can reduce the dosage frequency and provide a more sustained release of the hormone. Uses: Boc-t4 has potential applications in various fields of research and industry, including drug development, biomedical research, and agriculture. the compound can be used as a prodrug for thyroxine, providing a more sustained release of the hormone and reducing the dosage frequency. boc-t4 can also serve as a tool for studying the role of thyroxine in various physiological processes. Group: Amino acids. Alternative Names: N-(tert-Butyloxy)carbonyl-L-thyroxine, Boc-T4. CAS No. 88404-22-2. Molecular formula: C20H19I4NO6. Mole weight: 877. Purity: Peak Area by HPLC ≥95%. IUPACName: (2S)-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid. Canonical SMILES: CC (C) (C)OC (=O)N[C@@H] (CC1=CC (=C (C (=C1)I)OC2=CC (=C (C (=C2)I)O)I)I)C (=O)O. Catalog: ACM88404222.
Clodronate disodium tetrahydrate
Clodronate is a non-nitrogenous bisphosphonate that can bind to bone to reduce the bone resorption. It is used as an anti-osteoporotic drug for the prevention of osteoporosis in post-menopausal women and men. Uses: The treatment of osteoporosis. Synonyms: (Dichloromethylene)bisphosphonic Acid Disodium Salt Tetrahydrate; Sodium clodronate hydrate; Disodium [dichloro (phosphonato)methyl]phosphonic acid tetrahydrate. Grades: >98%. CAS No. 88416-50-6. Molecular formula: CH10Cl2Na2O10P2. Mole weight: 360.908.
Eptifibatide acetate
Eptifibatide acetate, an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class, is a cyclic heptapeptide constructed from 6 amino acids and a mercaptopropionyl residue. It reversibly binds to platelets to reduce the risk of cardiac ischemic events. Synonyms: L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-, cyclic (1?6)-disulfide, acetate (1:x); deamino-Cys(1)-hArg-Gly-Asp-Trp-Pro-Cys(1)-NH2.xCH3CO2H; deamino-cysteinyl-L-homoarginyl-glycyl-L-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide (1->7)-disulfide acetic acid; Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2 acetate. Grades: ≥95%. CAS No. 881997-86-0. Molecular formula: C35H49N11O9S2.xC2H4O2. Mole weight: 831.97 (free base).
Erythrosine B
Erythrosine B. Group: Biochemicals. Alternative Names: 3',6'-Dihydroxy-2',4',5',7'-tetraiodo-spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one; rythrosine B (6CI); Fluorescein, 2',4',5',7'-tetraiodo-, disodium salt (8CI); 1427 Red; 1671 Red; 2,4,5,7-Tetraiodofluorescein Disodium Salt; 2',4',5',7'-Tetraiodofluorescein Disodium Salt; AcidRed 51; Aizen Erythrosine; Aizen Food Red 3; Basovit Red 425E; C.I. 45430; C.I. AcidRed 51; C.I. Food Red 14; Calcocid Erythrosine N; Canacert Erythrosine BS; Ceplac; Cilefa Pink B; Cogilor Red 312.10; D and C Red No. 3; D&C Red No. 3; Dolkwal Erythrosine; E 127; Edicol Supra Erythrosin AS; Edicol Supra Erythrosine A; Erythrosin; Erythrosin B; Erythrosin B sodium salt; Erythrosin BS; Erythrosine; Erythrosine 307046; Erythrosine 36003; Erythrosine 37003; Erythrosine 3B; Erythrosine B-FO; Erythrosine BS; Erythrosine Bluish; Erythrosine Extra; Erythrosine Extra Conc. A Export; Erythrosine Extra Pure A; Erythrosine I; Erythrosine K-FO; Erythrosine TB; Erythrosine TB Extra; Erythrosine extra bluish; Eurocert Erythrosine 311807; FD & C Red No. 3-307020; FD and C Red 3; FD and C Red No. 3; FD&C Red No. 3; FD&C Red No. 3-37003; FDC Red 3; FDC Red 3 dye; Food Color Red 3; Food Dye Red 3; Food Red 14; Food Red 3; Food Red No. 3; Hexacert Red No. 3; Hexacol Erythrosine BS; Japan Food Red No. 3; Japan Red 3; Japan Red No. 3; Maple Erythrosine; Necol Erythrosine; Neelicol Erythrosine; New Pink Bluish Geigy; Red 1799; Red 3; Red No. 3; S 887; Simacid Pink 24107; Synerid; Tetraiodofluorescein Sodium Salt; Usacert FD & C Red No. 3-310116; Usacert Red No. 3; Water Pink 176575. Grades: Highly Purified. CAS No. 16423-68-0. Pack Sizes: 1g. Molecular Formula: C20H8I4Na2O5, Molecular Weight: 879.86. US Biological Life Sciences.
Worldwide
n-Propyl Alcohol, Reagent Grade, 500 mL
Formula: CH3CH2CH2OH, Formula Wt: 60. 09, Storage Code: Red; flammable. Group: chem-category alcohols. Alternative Names: 1-Propanol; Propylic acid. Grades: chem-grade reagent. CAS No. 71-23-8. Product ID: 884990. -- SOLD FOR EDUCATIONAL USE ONLY --
OAT-889
OAT-889 is a dual inhibitor of acidic mammalian chitinase (AMCase) and chitotriosidase-1 (CHIT1) (hAMCase IC50 = 9 nM;hCHIT1 IC50 = 26 nM), which has the potential to treat asthma. OAT-889 reduced the number of infiltrating leukocytes in bronchoalveolar lavage fluid (BALF) in an acute mouse model of lung inflammation, as well as decreased mRNA of proinflammatory cytokines, such as interleukin-13, interleukin-1 and Muc5AC in lung tissue. Uses: The treatment of asthma. Synonyms: OAT 889; OAT889.
PG490-88
PG490-88 is a semisynthetic derivative of the novel compound PG490 (triptolide) purified from a Chinese herb. It has been shown to prolong acute allograft survival in multiple experimental organ transplant models. However, the effect of PG490-88 on prevention of acute and chronic renal allograft rejection has not been determined. Kidneys of ACI or F344 rats were transplanted into bilaterally nephrectomized LEW recipients as the acute or chronic allograft rejection models, respectively. Treatment of LEW recipients with PG490-88 significantly prolonged ACI kidney graft survival in a dose-dependent manner when compared with the untreated allograft controls. LEW recipients of F344 kidney grafts who received PG490-88 for 90 days with a brief course of low-dose FK506 showed normal serum creatinine levels and markedly reduced histological changes of chronic rejection at day 90 after transplantation. These results suggest that PG490-88 significantly prolongs kidney allograft survival in an acute rejection model and prevents chronic allograft rejection in rats. Synonyms: Omtriptolide; PG490 88; YM 262; YM-262; YM262; 4-{[(3bS, 4aS, 5aR, 6R, 6aS, 7aS, 7bS, 8aS, 8bS)-6a-Isopropyl-8b-methyl-1-oxo-1, 3, 3b, 4, 4a, 6, 6a, 7a, 7b, 8b, 9, 10-dodecahydrotrisoxireno[6, 7:8a, 9:4b, 5]phenanthro[1, 2-c]furan-6-yl]oxy}-4-oxobutanoic acid. Grades: ≥98%. CAS No. 195883-06-8. Molecular formula: C24H28O9. Mole weight: 460.47.
Propionic Acid, Laboratory Grade, 500 mL
Formula: CH3CH2COOH. F. W: 74. 08. Characteristics: Colorless, oily liquid. Notes: Inhibits the growth of mold and some bacteria at the levels between 0. 1 and 1% by weight. Storage Code: Red; flammable. Alternative Names: Propanoic acid, methyl acetic acid. Grades: chem-grade laboratory. CAS No. 79-09-4. Product ID: 884938. -- SOLD FOR EDUCATIONAL USE ONLY --
(±)-Z-α-phosphonoglycine trimethyl ester
Starting material for the synthesis of (Z)-dehydroamino acids by Wittig-Horner reaction with aldehydes; the dehydroamino acids can be stereoselectively reduced to amino acids. Synonyms: (±)-Methyl 2-benzyloxycarbonylamino-2-(dimethoxyphosphinyl)acetate; (±)-Trimethyl Z-α-phosphonoglycinate; Methyl 2-(((benzyloxy)carbonyl)amino)-2-(dimethoxyphosphoryl)acetate; (+/-)-BENZYLOXYCARBONYL-ALPHA-PHOSPHONOGLYCINE TRIMETHYL ESTER; N-Cbz-2-phosphonoglycine Trimethyl Ester; (+/-)-Cbz-alpha-phosphonoglycine trimethyl ester; Cbz-alpha-Phosphono-DL-glycine trimethyl ester; (+/-)-N-Cbz-alpha-phosphonoglycine Trimethyl Ester. Grades: ≥ 99% (HPLC). CAS No. 88568-95-0. Molecular formula: C13H18NO7P. Mole weight: 331.27.
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