Acid Transaminase Suppliers USA
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Product | Description | |
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Vigabatrin (GABA Transaminase Inhibitor, Vigabatrin, gamma-Vinyl-GABA, Sabril, 4-Amino-5-hexenoic Acid) Quick inquiry Where to buy Suppliers range | A selective, irreversible inhibitor of GABA transaminase with antiepileptic properties. Covalently binds to the active site of GABA tansaminase to inactivate it in a dose-dependent manner and increases extracellular GABA levels in the brain. Rapidly absorbed following oral administration and is shown to inhibit [3H]GABA uptake across the apical membrane of Caco-2 cell monolayers in a concentration-dependent manner (IC50 = 2.9mM). Group: Biochemicals. Grades: Highly Purified. CAS No. 68506-86-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Aminooxyacetic Acid Quick inquiry Where to buy Suppliers range | Aminooxyacetic acid, often abbreviated AOA or AOAA, is a GABA transaminase (GABA-T) inhibitor (Ki = 9.16 μM) that inhibits 4-aminobutyrate aminotransferase (GABA-T) activity in vitro and in vivo, leading to less gamma-aminobutyric acid (GABA) being broken down. Subsequently, the level of GABA is increased in tissues. At concentrations high enough to fully inhibit 4-aminobutyrate aminotransferase activity, aminooxyacetic acid is indicated as a useful tool to study regional GABA turnover in rats. AOAA is also an inhibitor of pyridoxal phosphate (PLP)-dependent enzymes, which serve as an inhibitor by attacking the Schiff base linkage between PLP and the enzyme, forming oxime type complexes. Uses: Gaba agents. Synonyms: Aminooxyacetate; AOAA; 2-Aminooxyacetic acid; U 7524; U7524; U-7524. Grades: ≥95%. CAS No. 645-88-5. Molecular formula: C2H5NO3. Mole weight: 91.07. | |
Divalproex sodium Quick inquiry Where to buy Suppliers range | Divalproex Sodium, consisting of a compound of sodium valproate and valproic acid in a 1:1 molar relationship in an enteric coated form, is a HDAC inhibitor used in the treatment of epilepsy. It acts via binding to and inhibiting gamma-aminobutyric acid (GABA) transaminase. Uses: The treatment of epilepsy. Synonyms: NSC 694279; NSC-694279; NSC694279; EP 475; EP475; EP-475; Valproate semisodium; Depakote; Epival; Depakote ER. Grades: >98%. CAS No. 76584-70-8. Molecular formula: C16H31NaO4. Mole weight: 310.41. | |
D,L-Gabaculine, Hydrochloride (3-Amino-2,3-dihydrobenzoic Acid) Quick inquiry Where to buy Suppliers range | An irreversible inhibitor of mouse brain alpha-aminobutyric acid (GABA)-alpha-ketoglutarate transaminase. Group: Biochemicals. Alternative Names: 3-Amino-2,3-dihydrobenzoic Acid. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
L-2,4-Diaminobutyric acid dihydrochloride Quick inquiry Where to buy Suppliers range | . Uses: A pharmacological tool and potential chiral building block. it is also used as an internal standard for amino acid analysis. also found to inhibit gaba transaminase, thus producing an elevation of gaba level, and to have an antitumor activity in vitro a. Synonyms: L-Dab-OH 2HCl; (S)-2,4-Diaminobutyric acid dihydrochloride. Grades: ≥ 98% (HPLC). CAS No. 1883-09-6. Molecular formula: C4H10N2O2·2HCl. Mole weight: 191.14. | |
L-DABA Quick inquiry Where to buy Suppliers range | L-DABA, (L-2,4-Diaminobutyric acid) is a noncompetitive GABA transaminase inhibitor (IC50 > 500 μM) with antitumor activity in vivo and in vitro. Synonyms: (2S)-2,4-diaminobutanoic acid; 2,4-diaminobutyric acid; 2,4-diaminobutyric acid dihydrochloride, (+-)-isomer; 2,4-diaminobutyric acid dihydrochloride, (S)-isomer; 2,4-diaminobutyric acid monohydrochloride, (+-)-isomer; 2,4-diaminobutyric acid monohydrochloride, (S)-isomer; 2,4-diaminobutyric acid, (+)-isomer; 2,4-diaminobutyric acid, (+-)-isomer; 2,4-diaminobutyric acid, (R)-isomer; 2,4-diaminobutyric acid, (S)-isomer; L-2,4-diaminobutyric acid. CAS No. 1758-80-1. Molecular formula: C4H10N2O2. Mole weight: 118.13. | |
Phenelzine Sulfate Quick inquiry Where to buy Suppliers range | A hydrazine derivative that is a non-selective and irreversible monoamine oxidase inhibitor (MAOI) and also inhibits GABA-transaminase (GABA-T), markedly increasing brain GABA levels. It is an antidepressant and anxiolytic used in the treatment of major depressive disorder (MDD) as well as other neural disorders. Group: Biochemicals. Alternative Names: (2-Phenylethyl)hydrazine dihydrogen sulfate; ( β-Phenylethyl)hydrazine dihydrogen sulfate; 2-Phenethylhydrazine sulfate; Estinerval; Fenelzin; Kalgan; Mao-rem; NSC 170957; Nardelzine; Nardil; Phenelzine Acid Sulfate; Phenelzine Bisulfate; Phenelzine Dihydrogen Sulfate; Phenelzine Hydrogen Sulfate; Phenethylhydrazine Sulfate; Stinerval; W 1544A. Grades: Highly Purified. CAS No. 156-51-4. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
Schisantherin B Quick inquiry Where to buy Suppliers range | Schisantherin B shows good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffering from chronic virus hepatitis. Uses: Hepatoprotection. Synonyms: SCHISANTHERIN B; 2-BUTENOIC ACID, 2-METHYL-, (5S,6S,7S,13AS)-5,6,7,13A-TETRAHYDRO-6-HYDROXY-1,2,3,13-TETRAMETHOXY-6,7-DIMETHYLBENZO[3,4]CYCLOOCTA[1,2-F][1,3]BENZODIOXOL-5-YL ESTER, (2Z)-; SCHISANTHERIN B 98.0% BY HPLC; GOMISINB; (5S)-5,6,7,8-Tetrahydro-1,2,3,13-tetramethoxy-6,7β-dimethylbenzo[3,4]cycloocta[1,2-f][1,3]benzodioxole-5α,6β-diol 5-[(Z)-2-methyl-2-butenoate]; (5S)-6α,7β-Dimethyl-1,2,3,12-tetramethoxy-10,11-methylenedioxy(5,6,7,8-tetrahydrodibenzo[a,c]cyclooctene)-5α,6β-diol 5-[(Z)-2-methyl-2-butenoate]; 2-Butenoic acid, 2-methyl-, (5S,6S,7S,13as)-5,6,7,13A-tetrahydro-6-hydroxy-1,2,3,13-tetramethoxy-6,7-dimethylbenzo[3,4]cycloocta[1,2-F][1,3]benzodioxol-5-yl ester, (2Z)-; (2Z)-2-Methyl-2-butenoic acid(5S,6S,7S,13aS)-5,6,7,8-tetrahydro-6-hydroxy-1,2,3,13-tetramethoxy-6,7-dimethylbenzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-5-yl ester. Grades: >98%. CAS No. 58546-55-7. Molecular formula: C28H34O9. Mole weight: 514.56. | |
Vigabatrin Quick inquiry Where to buy Suppliers range | Vigabatrin is an analogue of gamma-aminobutyric acid(GABA) and is an irreversible inhibitor of 4-aminobutyrate transaminase. It is used in combination with other agents as therapy of refractory complex partial seizures and as monotherapy for infantile spasms. It is an antiepileptic drug that inhibits the breakdown of GABA by acting as a suicide inhibitor of GABA transaminase (GABA-T). It increases brain concentrations of GABA, an inhibitory neurotransmitter in the CNS, by irreversibly inhibiting enzymes that catabolize GABA or block the reuptake of GABA into glia and nerve endings. It may also work by suppressing repetitive neuronal firing through inhibition of voltage-sensitive sodium channels. It is a racemic compound, and its [S]-enantiomer is pharmacologically active. It has been listed. Uses: Vigabatrin is used in combination with other agents as therapy of refractory complex partial seizures and as monotherapy for infantile spasms. it is an antiepileptic drug. Synonyms: γ-Vinyl-GABA; 4-Amino-5-hexenoic Acid; (±)-4-Amino-5-hexenoic Acid; Sabril; Vigabatrine; 4-Aminohexenoic acid; rac-Vigabatrin; (±)-Vigabatrin; (±)-4-Aminohexenoic acid. Grades: ≥98%. CAS No. 68506-86-5. Molecular formula: C6H11NO2. Mole weight: 129.16. | |
Vigabatrin EP Impurity B Quick inquiry Where to buy Suppliers range | An impurity of Vigabatrin. Vigabatrin is an inhibitor of the enzyme GABA transaminase (GABA-T) used as an antiepileptic drug. Synonyms: UNII-6GON7WT3C8; (2E)-2-(2-Aminoethyl)but-2-enoic acid; 2-(2-Aminoethyl)but-2-enoic acid, (2E)-; 6GON7WT3C8; (E)-2-(2-aminoethyl)but-2-enoic acid. CAS No. 1379504-35-4. Molecular formula: C6H11NO2. Mole weight: 129.16. | |
Vigabatrin EP Impurity E Quick inquiry Where to buy Suppliers range | Vigabatrin EP Impurity E is a derivative of Vigabatrin. Vigabatrin is an inhibitor of the enzyme GABA transaminase (GABA-T) used as an antiepileptic drug. Synonyms: 2-(2-Aminobut-3-enyl)malonic Acid. CAS No. 1378466-25-1. Molecular formula: C7H11NO4. Mole weight: 173.17. | |
Vigabatrin EP Impurity F Quick inquiry Where to buy Suppliers range | An impurity of Vigabatrin. Vigabatrin is an inhibitor of the enzyme GABA transaminase (GABA-T) used as an antiepileptic drug. Synonyms: 4-(4-Amino-hex-5-enoylamino)-hex-5-enoic Acid; 4-[(4-Amino-1-oxo-5-hexenyl)amino]-5-hexenoic Acid; 4-[(4-Amino-1-oxo-5-hexen-1-yl)amino]-5-hexenoic Acid. CAS No. 794466-81-2. Molecular formula: C12H20N2O3. Mole weight: 240.3. |