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| Product | Description | |
|---|---|---|
| Aconitic acid | Aconitic acid (NSC 7616) is an organic acid, and can be isolated from seeds of Brassica oleracea var. acephala (kale). Aconitic acid has antifungal activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC 7616. CAS No. 499-12-7. Pack Sizes: 25 mg; 50 mg. Product ID: HY-W016814A. |  |
| Aconitic Acid | Solid;Solid;colourless or yellow crystals, leaves, or plates; pleasant winey acid taste; almost odourless. Group: Polymers. Product ID: (Z)-prop-1-ene-1,2,3-tricarboxylic acid. Molecular formula: 174.11g/mol. Mole weight: C6H6O6. C(C(=CC(=O)O)C(=O)O)C(=O)O. InChI=1S/C6H6O6/c7-4 (8)1-3 (6 (11)12)2-5 (9)10/h1H, 2H2, (H, 7, 8) (H, 9, 10) (H, 11, 12)/b3-1-. GTZCVFVGUGFEME-IWQZZHSRSA-N. |  |
| cis-Aconitic acid | 5g Pack Size. Group: Analytical Reagents, Biochemicals, Building Blocks, Organics. Formula: HO2CCH2C(CO2H)=CHCO2H. CAS No. 585-84-2. Prepack ID 49708657-5g. Molecular Weight 174.11. See USA prepack pricing. |  |
| cis-Aconitic Acid | cis-Aconitic Acid. Group: Biochemicals. Alternative Names: (Z)-Aconitic Acid; NSC 227901; (1Z)-1-Propene-1,2,3-tricarboxylic Acid. Grades: Highly Purified. CAS No. 585-84-2. Pack Sizes: 1g. Molecular Formula: C6H6O6, Molecular Weight: 174.11. US Biological Life Sciences. |  Worldwide |
| trans-Aconitic acid | 25g Pack Size. Group: Aroma Chemicals, Building Blocks, Organics. Formula: C6H6O6. CAS No. 4023-65-8. Prepack ID 16739536-25g. Molecular Weight 174.11. See USA prepack pricing. | |
| trans-Aconitic acid | trans-Aconitic acid is present in normal human urine, and it has been suggested that is present in larger amounts with Reye's syndrome and organic aciduria. trans-Aconitic acid is a substrate of enzyme trans-aconitate 2-methyltransferase. Uses: Scientific research. Group: Natural products. CAS No. 4023-65-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W016813. | |
| trans-Aconitic Acid | Solid;Solid;colourless or yellow crystals, leaves, or plates; pleasant winey acid taste; almost odourless. Group: Heterocyclic organic compounddicarboxylic acid monomers. Alternative Names: (E)-1-Propene-1,2,3-tricarboxylic Acid. CAS No. 4023-65-8. Molecular formula: C6H6O6. Mole weight: 174.11 g/mol. Appearance: White to Light Yellow Powder to Crystal. Purity: 98.0%(T)(HPLC). IUPACName: (E)-Prop-1-ene-1,2,3-tricarboxylic acid. Canonical SMILES: C(C(=CC(=O)O)C(=O)O)C(=O)O. Density: 0.56 g/cm³ at 20 °C. ECNumber: 223-688-6;207-877-0. Catalog: ACM-MO-4023658. |  |
| trans-Aconitic Acid | trans-Aconitic Acid. Group: Biochemicals. Alternative Names: (1E)-1-Propene-1,2,3-tricarboxylic Acid; (E)-Aconitic Acid; trans-1-Propene-1,2,3-tricarboxylic Acid. Grades: Highly Purified. CAS No. 4023-65-8. Pack Sizes: 5g. Molecular Formula: C6H6O6, Molecular Weight: 174.11. US Biological Life Sciences. | Worldwide |
| Trans-Aconitic Acid | Solid;Solid;colourless or yellow crystals, leaves, or plates; pleasant winey acid taste; almost odourless. Group: Monomers. Alternative Names: Achilleic acid. CAS No. 4023-65-8. Product ID: (E)-Prop-1-ene-1,2,3-tricarboxylic acid. Molecular formula: 174.11. Mole weight: C6H6O6. C(C(=CC(=O)O)C(=O)O)C(=O)O. InChI=1S/C6H6O6/c7-4 (8)1-3 (6 (11)12)2-5 (9)10/h1H, 2H2, (H, 7, 8) (H, 9, 10) (H, 11, 12)/b3-1+. GTZCVFVGUGFEME-HNQUOIGGSA-N. 98%. | |
| aconitate decarboxylase | This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. This enzyme participates in c5-branched dibasic acid metabolism. Group: Enzymes. Synonyms: cis-aconitic decarboxylase; CAD; cis-aconitate carboxy-lyase. Enzyme Commission Number: EC 4.1.1.6. CAS No. 9025-1-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4806; aconitate decarboxylase; EC 4.1.1.6; 9025-01-8; cis-aconitic decarboxylase; CAD; cis-aconitate carboxy-lyase. Cat No: EXWM-4806. |  |
| Triethyl aconitate | Triethyl aconitate (CAS# 5349-99-5 ) is a useful research chemical. Synonyms: cis-propene-1,2,3-tricarboxylicacidtriethylester; cispropene-1,2,3-tricarboxylicacidtriethylester; triethyl 1-propene-1,2,3-tricarboxylate; 1-Propene-1,2,3-tricarboxylic acid triethyl ester; Aconitic acid triethyl ester. CAS No. 5349-99-5. Molecular formula: C12H18O6. Mole weight: 258.27. |  |
| Trimethyl Aconitate | Protected Aconitic Acid. Group: Biochemicals. Alternative Names: 1-Propene-1,2,3-tricarboxylic Acid 1,2,3-Trimethyl Ester; Aconitic Acid Trimethyl Ester; NSC 67343. Grades: Highly Purified. CAS No. 20820-77-3. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
| Trimethyl (E)-Aconitate | Protected trans-Aconitic Acid. Group: Biochemicals. Alternative Names: (1E)-1-Propene-1,2,3-tricarboxylic Acid 1,2,3-Trimethyl Ester; Trimethyl trans-Aconitate; trans-Aconitic Acid Trimethyl Ester. Grades: Highly Purified. CAS No. 4271-99-2. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
| 4-Octyl itaconate | 4-Octyl itaconate is a prodrug form of itaconate, an endogenous cellular metabolite produced via decarboxylation of cis-aconitate by the enzyme encoded by IRG1. It activates Nrf2. It inhibits LPS-induced increases in IL-1β mRNA, HIF-1α and IL-10 in macrophages. It decreases cytokine production in response to LPS in mice and prolongs survival. Synonyms: Itaconic acid 4-octyl ester; 2-Methylidene-4-octoxy-4-oxobutanoic acid. Grades: ≥98%. CAS No. 3133-16-2. Molecular formula: C13H22O4. Mole weight: 242.3. | |
| Acetylaconitine | Acetylaconitine is a diterpenoid alkaloid that is extracted from the roots of aconite plants. It has been used as a medicine for centuries in China and Japan. Acetylaconitine has shown anti-inflammatory properties and has been used clinically to treat inflammatory diseases, such as cancer and arthritis. Acetylaconitine binds to fatty acids, which may be due to its unsaturated alkyl chain. Acetylaconitine also blocks the action of calcium ions on cells, preventing them from releasing histamine. This drug also blocks the synthesis of prostaglandins by inhibiting cyclooxygenase activity in the cell membrane. Acetylaconitine is toxic to humans and animals because it inhibits respiration by blocking cellular respiration at mitochondria level. Group: Other alkaloids. CAS No. 77181-26-1. Molecular formula: C36H49NO12. Mole weight: 687.77 g/mol. Canonical SMILES: CCN1C[C@@]2 ([C@@H] (C[C@@H] ([C@@]34[C@@H]2[C@H] ([C@@H] (C31)[C@@]5 ([C@@H]6[C@H]4C[C@@] ([C@@H]6OC (=O)C7=CC=CC=C7) ([C@H] ([C@@H]5O)OC)O)OC (=O)C)OC)OC)OC (=O)C)COC. Catalog: ACM77181261. | |
| cis-Aconitic Anhydride | This product is suitable for scientific research. Group: Polymer/macromoleculeanhydride monomers. Alternative Names: 2,5-Dihydro-2,5-dioxo-3-furanacetic Acid. CAS No. 6318-55-4. Molecular formula: C6H4O5. Mole weight: 156.09 g/mol. Appearance: Powder or Crystalline. Purity: 0.98. Canonical SMILES: OC(=O)CC1=CC(=O)OC1=O. ECNumber: 228-663-3. Catalog: ACM-MO-6318554. | |
| Denudatine | Denudatine is an alkaloid found in the plant families, Aconitum and Veratrum. It is a diterpenoid alkaloid with a structural skeleton that contains an asymmetric carbon atom. Denudatine can be synthesized by reacting acetylacetone with acetic acid and hydrogen chloride gas in a reaction solution. The nmr spectra of denudatine show signals at δ 5.6 (1H), 3.2 (3H), 1.32 (3H) and 1.06 ppm (3H). The chemical reactions of denudatine involve the formation of fatty acids, which are used to produce various substances such as carotenoids, steroids, and vitamin D2. Denudatine has been shown to have receptor binding activity, similar to that of aconitine alkaloids from the genus Aconitum or c19-diterpenoid alkaloids from the genus Ver. Group: Other alkaloids. CAS No. 26166-37-0. Molecular formula: C22H33NO2. Mole weight: 343.5 g/mol. Canonical SMILES: CCN1C[C@@]2 (CCC[C@@]34[C@@H]2C[C@@H] (C31)[C@]56[C@H]4[C@H] ([C@H] (CC5)C (=C)[C@H]6O)O)C. Catalog: ACM26166370. | |
| Ds(+)-threo-Isocitric acid trisodium salt | Anticoagulant that retains platelets functionality. Buffers Ca2+ activity in physiological range (~1mM). Bypasses the metabolic blockade, may permit heme biosynthesis but does not suffice to reverse the iron-restriction response. Stabilizes the iron-sulfur cluster and is predicted to restore aconitase to its 'high iron' conformation and thereby dissociates the PKC-associated signaling complexes whose hyperactivation impairs Epo responsiveness. Binds IDH (isocitrate dehydrogenase), an excellent candidate for participating, along with aconitase and PKC, in an iron restriction signalosome. Contributes to heme biosynthesis which may account for its greater potency in restoring erythroid differentiation. Group: Biochemicals. Alternative Names: (1R,2S)-1-Hydroxy-1,2,3-propanetricarboxylic acid; (2R,3S)-Isocitric acid trisodium salt. Grades: Highly Purified. CAS No. 903507-52-8. Pack Sizes: 25mg, 100mg. Molecular Formula: C6H5O7 3Na, Molecular Weight: 258.1. US Biological Life Sciences. | Worldwide |
| Jesaconitine | Jesaconitine is a natural compound that has been shown to have anti-inflammatory properties. It has been shown to inhibit the activity of cyclooxygenase and lipoxygenase enzymes, which are involved in the production of prostaglandins. Jesaconitine also inhibits the expression of nuclear DNA and suppresses myeloma cells by inhibiting their ability to synthesize proteins. Jesaconitine has also been shown to inhibit chronic arthritis in animal models by suppressing inflammation and preventing joint damage. This compound is not active against nonsteroidal anti-inflammatory drugs such as ibuprofen, diclofenac, and naproxen. Jesaconitine can be extracted from the plant Angelica Dahurica or synthesized in laboratories. It is soluble in trifluoroacetic acid (TFA) and can be analyzed using nuclear magnetic resonance spectroscopy with high values for matrix effect and control analysis. Group: Other alkaloids. Alternative Names: Diesaconitine(1a,3a,6a,14a,15a,16b)-20-Ethyl-1,6,16-triMethoxy-4-(MethoxyMethyl)-aconitane-3,8,13,14,15-pentol 8-Acetate 14-(4-Meth oxybenzoate). CAS No. 16298-90-1. Molecular formula: C35H49NO12. Mole weight: 675.76 g/mol. Canonical SMILES: CCN1C[C@@]2 ([C@@H] (C[C@@H] ([C@@]34[C@@H]2[C@H] ([C@@H] ([C@H]31)[C@@]5 ([C@@H]6[C@H]4C[C@@] ([C@@H]6OC (=O)C7=CC=C (C=C7)OC) ([C@H] ([C@@H]5O)OC)O)OC (=O)C)OC)OC)O)COC. Catalog: ACM16298901. | |
| Native Porcine Aconitase | Aconitase catalyses the stereo-specific isomerization of Citrate to Isocitrate via cis-aconitate in the tricarboxylic acid cycle. Aconitase is inhibited by cyanide, sulfide and copper and mercury at low concentRations. It is competitively inhibited by trans-aconitate. Aconitase contains an internal Fe-S cluster which is responsible for its activity. Crude preparation containing aconitase activity. Applications: Aconitase may be usefull in diabetes research as well as to study structural conservation between iron-responsive element binding proteins (ire-bp) and isomerases. Group: Enzymes. Synonyms: cis-aconitase; aconitase; Citrate hydro-lyase; Citrate (Isocitrate) hydro-lyase; EC 4.2.1.3; 9024-25-3; aconitate hydRatase. Enzyme Commission Number: EC 4.2.1.3. CAS No. 9024-25-3. Aconitase. Storage: -20°C. Source: Porcine heart. Species: Porcine. cis-aconitase; aconitase; Citrate hydro-lyase; Citrate (Isocitrate) hydro-lyase; EC 4.2.1.3; 9024-25-3; aconitate hydRatase. Cat No: NATE-0024. | |
| Oxalomalic acid sodium salt | Oxalomalic acid is an inhibitor of both aconitase and NADP-dependent isocitrate dehydrogenase, At 5 mM, oxalomalic acid inhibition of aconitase leads to a decrease in the binding activity of IRP1 and a decrease in glutamate secretion in cultured lens epithelial cells, retinal pigment epithelial cells, and neurons. Synonyms: Oxalomalic acid trisodium salt. Grades: ≥95%. CAS No. 89304-26-7. Molecular formula: C6H6O8·3Na. Mole weight: 275. | |
| Oxalomalic acid trisodium | Oxalomalic acid (Oxalomalate) trisodium is a aconitase and NADP-dependent isocitrate dehydrogenase inhibitor. Oxalomalic acid trisodium inhibits nitrite production and iNOS protein expression in lipopolysaccharide (HY-D1056)-activated J774 macrophages [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Oxalomalate trisodium. CAS No. 89304-26-7. Pack Sizes: 5 mg. Product ID: HY-131521. | |
| phosphinomethylmalate isomerase | The enzyme, characterized from the bacterium Streptomyces viridochromogenes, is involved in bialaphos biosynthesis. The enzyme from the bacterium Kitasatospora phosalacinea participates in the biosynthesis of the related compound phosalacine. Both compounds contain the nonproteinogenic amino acid L-phosphinothricin that acts as a potent inhibitor of EC 6.3.1.2, glutamine synthetase. The similar enzyme EC 4.2.1.3, aconitate hydratase, cannot catalyse this reaction. Group: Enzymes. Synonyms: pmi (gene name). Enzyme Commission Number: EC 4.2.1.166. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5007; phosphinomethylmalate isomerase; EC 4.2.1.166; pmi (gene name). Cat No: EXWM-5007. | |
| Tricarballylic acid | Tricarballylic acid, a conjugate acid of a tricarballylate, is a competitive inhibitor of the enzyme aconitate hydratase (aconitase; EC 4.2.1.3) with a K i value of 0.52 mM [1]. Uses: Scientific research. Group: Natural products. CAS No. 99-14-9. Pack Sizes: 10 mM * 1 mL; 5 g. Product ID: HY-W020215. | |
| Xanthotoxol | A hydroxylated psoralen that inhibits neutrophil infiltration and brain edema induced by focal cerebral ischemia-reperfusion injury in rats. A potentially useful antiarrhythmic agent. It has been shown to be effective in the prevention of ventricular fibrillation of mice induced by chloroform, of rats induced by calcium chloride, and in treatment of rat arrhythmia induced by aconitine. Recent studies show that it may also have antioxidant and anticancer activities. Group: Biochemicals. Alternative Names: 9-Hydroxy-7H-furo[3,2-g][1]benzopyran-7-one; 6,7-Dihydroxy-5-benzofuranacrylic Acid δ-Lactone; 3-(6,7-Dihydroxy-5-benzofuranyl)-2-propenoic Acid δ-Lactone; 8-Hydroxypsoralen; NSC 401269. Grades: Highly Purified. CAS No. 2009-24-7. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
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