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From the kiwi fruit or Chinese gooseberry (Actinidia chinensis). In peptidase family C1 (papain family). Group: Enzymes. Synonyms: actinidin; Actinidia anionic protease; proteinase A2 of Actinidia chinensis. Enzyme Commission Number: EC 3.4.22.14. CAS No. 39279-27-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4194; actinidain; EC 3.4.22.14; 39279-27-1; actinidin; Actinidia anionic protease; proteinase A2 of Actinidia chinensis. Cat No: EXWM-4194.
actin-like protein (12-21)
Actinobolin
Actinobolin is a broad-spectrum antibiotic isolated from Str. griseoviridus var. atrofaczens. Actinobolin has antibacterial activity, but it can be offset by a variety of amino acids or pyruvate. It has inhibitory effect on Ehrlich ascites tumor, sarcoma 180, etc. Synonyms: 4-(2-Aminopropionamido)-3,4,4a,5,6,7-hexahydro-5,6,8-trihydroxy-3-methylisocoumarin. CAS No. 24397-89-5. Molecular formula: C13H20N2O6. Mole weight: 300.31.
Actinoidin A
Actinoidin A is a glycopeptide antibiotic isolated from Nocardia sp.(SK&F-AAJ-193). Actinoidin A is mainly against Gram-positive bacteria, including Staphylococcus and Enterococcus bacteria. Synonyms: Avoparcinone alpha, 44-O-(2-O-(3-amino-2,3,6-trideoxy-alpha-L-arabino-hexopyranosyl)-beta-D-glucopyranosyl)-22-O-(3-amino-2,3,6-trideoxy-4-O-methyl-alpha-L-arabino-hexopyranosyl)-3-de(4-hydroxyphenyl)-62-demethyl-30-O-alpha-D-mannopyranosyl-3-(phenylmethyl)-. CAS No. 60382-78-7. Molecular formula: C84H94ClN9O31. Mole weight: 1761.14.
Actinomycin c3
Actinomycin c3. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ACTINOMYCIN C3. Product Category: Heterocyclic Organic Compound. CAS No. 6156-47-4. Molecular formula: C64H90N12O16. Mole weight: 1283.47. Product ID: ACM6156474. Alfa Chemistry ISO 9001:2015 Certified. Categories: Actinomycin C1.
Actinomycin D
25mg Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C62H86N12O16. CAS No. 50-76-0. Prepack ID 32117981-25mg. Molecular Weight 1255.42. See USA prepack pricing.
Actinomycin D
2mg Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C62H86N12O16. CAS No. 50-76-0. Prepack ID 32117981-2mg. Molecular Weight 1255.42. See USA prepack pricing.
Actinomycin D
5mg Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C62H86N12O16. CAS No. 50-76-0. Prepack ID 32117981-5mg. Molecular Weight 1255.42. See USA prepack pricing.
Actinomycin D
Actinomycin D is a chromopeptide antineoplastic antibiotic that exhibits high antibacterial and antitumor activity. Actinomycin D binds to single- and double-stranded DNA and subsequent inhibition of RNA and protein synthesis. Synonyms: Actinomycin; Cosmegen; Cosmegen Lyovac; Dactinomycin; Lyovac Cosmegen. CAS No. 50-76-0. Molecular formula: C62H86N12O16. Mole weight: 1255.41.
Actinomycin D, 7-Amino- - CAS 7240-37-1
7-Aminoactinomycin D, like its parent molecule, actinomycin D, is a DNA intercalator and has antibacterial properties. Exhibits growth-inhibitory activity against certain leukemias and sarcomas. Group: Fluorescence/luminescence spectroscopy.
Actinomycin D (Dactinomycin)
Suitable for use in nucleic acid inhibition. Actinomycin D inhibits the proliferation of cells in a cell-cycle nonspecific way by forming a stable complex with DNA (via deoxyguanosine residues), thus inhibiting DNA-primed RNA synthesis. It is used in cell culture as a selection agent. Antibiotic. Antitumor compound. Cytotoxic. Apoptosis inducer. RNA synthesis inhibitor. DNA intercalating agent. Mcl-1 expression inhibitor. p53 pathway activator. Source:Streptomyces sp. Group: Biochemicals. Alternative Names: Streptomyces antibioticus; 2-Amino- (N, N) -1-bis (hexadeca hydro-6, 13-diisopropyl -2, 5, 9-tri methyl -1, 4, 7, 11, 14-pentaoxo-1H-pyrrolo [2, 1] - [1, 4, 7, 10, 13] oxatetra azacyclohexadecin-10-yl ) -4, 6-di methyl -3-oxo-3H-phenoxazine-1, 9-dicarboxamide ; Dactinomycin, Actinomycin IV, Actinomycin C1; Actactinomycin A IV; Actinomycin 7; Dilactone Actinomycindioic D Acid; Lyovac Cosmegen; Cosmogen; Meractinomycin. Grades: Cell Culture Grade. CAS No. 50-76-0. Pack Sizes: 5mg, 10mg, 25mg, 100mg, 500mg. Molecular Formula: C62H86N12O16, Molecular Weight: 1255.43. US Biological Life Sciences.
Worldwide
Actinomycin e2
Actinomycin e2. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ACTINOMYCIN E2. Product Category: Heterocyclic Organic Compound. CAS No. 1402-42-2. Molecular formula: C66H94N12O16. Mole weight: 1311.52. Product ID: ACM1402422. Alfa Chemistry ISO 9001:2015 Certified. Categories: Actinomycine.
actinomycin lactonase
This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. Group: Enzymes. Enzyme Commission Number: EC 3.1.1.39. CAS No. 37288-09-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3465; actinomycin lactonase; EC 3.1.1.39; 37288-09-8. Cat No: EXWM-3465.
Actinonin
Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces. Actinonin inhibits aminopeptidase M , aminopeptidase N and leucine aminopeptidase. Actinonin is a potent reversible peptide deformylase (PDF) inhibitor with a K i of 0.28 nM. Actinonin also inhibits MMP-1 , MMP-3 , MMP-8 , MMP-9 , and hmeprin α with K i values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin is an apoptosis inducer. Actinonin has antiproliferative and antitumor activities [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Actinonin. CAS No. 13434-13-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113952.
Actinoplanones A
Actinoplanones were isolated from the Actinoplanes sp. R-304. Actinoplanone A was extremely cytotoxic against HeLa cells and also has antifungal and bacterial activity. Synonyms: (1R)-13-Amino-11-chloro-1alpha, 4beta-dimethoxy-12-methyl-3beta, 15, 16-trihydroxy-3, 4, 8abeta, 13-tetrahydro-1H-xantheno[4', 3', 2':4, 5][1, 3]benzodioxino[7, 6-g]isoquinoline-14, 17(2H, 9H)-dione. Molecular formula: C28H25N2O10Cl. Mole weight: 584.96.
Actinoplanones B
Actinoplanones were isolated from the Actinoplanes sp. R-304. Actinoplanone B was extremely cytotoxic against HeLa cells. Molecular formula: C28H25NO10Cl. Mole weight: 570.95.
Actinopyrone A
Actinopyrone A is a gamma-pyrone compound isolated from a Streptomyces sp. It shows selective (>10e6 fold) and potent (MIC 0.0001 ug/ml) activity against Helicobacter pylori, the principle cause of peptic ulcer disease. Actinopyrone A was originally identified for its coronary vasodilating activity and weak activity against some Gram-positive bacteria and dermatophytes. Group: Biochemicals. Grades: Highly Purified. CAS No. 88378-59-0. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Actinopyrone A
Actinopyrone A is an antibiotic isolated from Streptomyces pacttm. Actinopyrone has a relaxing effect on the coronary blood vessels of anesthetized dogs, and has weak anti-gram-positive bacteria and trichoderma activity. Synonyms: 4H-Pyran-4-one, 2-(10-hydroxy-3,7,9,11-tetramethyl-2,5,7,11-tridecatetraenyl)-6-methoxy-3,5-dimethyl-. Grades: >95%. CAS No. 88378-59-0. Molecular formula: C25H36O4. Mole weight: 400.55.
Actinopyrone b
Actinopyrone b. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ACTINOPYRONE B;2-(10-Hydroxy-3,7,9,11-tetramethyl-2,5,7,11-tridecatetrenyl)-6-methoxy-3-methyl-4H-pyran-4-one. Product Category: Heterocyclic Organic Compound. CAS No. 88378-60-3. Molecular formula: C24H34O4. Mole weight: 386.52. Product ID: ACM88378603. Alfa Chemistry ISO 9001:2015 Certified.
Actinopyrone B
Actinopyrone B is an antibiotic isolated from Streptomyces pacttm. Actinopyrone has a relaxing effect on the coronary blood vessels of anesthetized dogs, and has weak anti-gram-positive bacteria and trichoderma activity. Synonyms: 4H-Pyran-4-one, 2-(10-hydroxy-3,7,9,11-tetramethyl-2,5,7,11-tridecatetraenyl)-6-methoxy-3-methyl-. Grades: 95%. CAS No. 88378-60-3. Molecular formula: C24H34O4. Mole weight: 386.52.
Actinopyrone C
Actinopyrone C is an antibiotic isolated from Streptomyces pacttm. Actinopyrone has a relaxing effect on the coronary blood vessels of anesthetized dogs, and has weak anti-gram-positive bacteria and trichoderma activity. Synonyms: 4H-Pyran-4-one, 3-ethyl-6-(10-hydroxy-3,7,9,11-tetramethyl-2,5,7,11-tridecatetraenyl)-2-methoxy-5-methyl-. Grades: 95%. CAS No. 88378-61-4. Molecular formula: C26H38O4. Mole weight: 414.58.
Actinorhodin
Actinorhodin is a kind of benzoisochromanqunone antibiotic isolated from Str. coelicolor. Actinorhodin has weak antibacterial and antiviral (HIV) ability. Synonyms: UNII-G4HH387T6Z; G4HH387T6Z; 3,3,4,4,5,5,10,10-Octahydro-6,6,9,9-tetrahydroxy-1β,1β-dimethyl-5,5,10,10-tetraoxo-8,8-bi[1H-naphtho[2,3-c]pyran]-3α,3α-diacetic acid. CAS No. 1397-77-9. Molecular formula: C32H26O14. Mole weight: 634.54.
A unique tetrasaccharide with six tiglate esters from an Amycolatopsis sp., actinotetraose hexatiglate possesses a two-fold axis of symmetry and is a co-metabolite of quinaldopeptin. Group: Biochemicals. Grades: Highly Purified. CAS No. 216590-44-2. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Actinotetraose Hexatiglate
A unique tetrasaccharide with six tiglate esters isolated from an unidentified amycolatopsis culture. It is a potent antitumour agent. Synonyms: Tigloside; 2-[(2E)-2-Methyl-2-butenoate]-O-3,4-bis-O-[(2E)-2-methyl-1-oxo-2-buten-1-yl]-β-D-glucopyranosyl-(1?2)-6-O-[(2E)-2-methyl-1-oxo-2-buten-1-yl]-α-D-glucopyranosyl O-3,4-bis-O-[(2E)-2-methyl-1-oxo-2-buten-1-yl]-β-D-glucopyranosyl-(1?2)-α-D-Glucopyranoside; 2-O-[3,4-bis-O-[(2E)-2-methyl-1-oxo-2-butenyl]-β-D-glucopyranosyl]-6-O-[(2E)-2-methyl-1-oxo-2-butenyl]-α-D-glucopyranosyl 2-O-[3,4-bis-O-[(2E)-2-Methyl-1-oxo-2-butenyl]-β-D-glucopyranosyl]-α-D-Glucopyranoside 6-[(2E)-2-Methyl-2-butenoate]. Grades: >95% by HPLC. CAS No. 216590-44-2. Molecular formula: C54H78O27. Mole weight: 1159.18.
A potent in vivo inhibitor of collagenase. Group: Biochemicals. Alternative Names: N4-Hydroxy-N1-[(1S)-1[[(2S)-2-(hydroxymethyl)-1-pyrroldinyl]carbonyl]-2-methylpropyl]-2-pentyl-,(2R)-(9CI). Grades: Highly Purified. CAS No. 13434-13-4. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Alpha-actinin-4 (118-127)
Alpha-actinin-4 (118-127) is a bioactive peptide of Alpha-actinin-4. F-actin cross-linking protein is thought to anchor actin to a variety of intracellular structures. Alpha-actinin-4 also functions as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA. Synonyms: Non-muscle alpha-actinin 4 (118-127).
The enzyme, characterized from the fruit fly Drosophila melanogaster, is a multi-domain oxidoreductase that acts as an F-actin disassembly factor. The enzyme selectively reduces two L-Met residues of F-actin, causing fragmentation of the filaments and preventing repolymerization. Free methionine is not a substrate. The reaction is stereospecific and generates the (R)-sulfoxide. Group: Enzymes. Synonyms: MICAL (gene name). Enzyme Commission Number: EC 1.14.13.225. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0828; F-actin monooxygenase; EC 1.14.13.225; MICAL (gene name). Cat No: EXWM-0828.
Monoclonal Anti-Actin (20-33) antibody produced in rabbit
In enzymology, a creatinase (EC 3.5.3.3) is an enzyme that catalyzes the chemical reaction:creatine + H2O? sarcosine + urea. Thus, the two substrates of this enzyme are creatine and H2O, whereas its two products are sarcosine and urea. This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. Creatinase accelerates the conversion reaction of creatine and water molecule to sarcosine and urea. It always acts in homodimer state and is induced by choline chloride. Applications: Creatinase mixed with sarcosine oxidase may be used to determine the level of creatine in different ph, temperature, enzyme ratio, and buffer concentration. it may also be used to determine the plasma creatinine level by using a centrifugal analyser. Group: Enzymes. Synonyms: Creatine amidinohydrolase; creatinase; 37340-58-2; EC 3.5.3.3. Enzyme Commission Number: EC 3.5.3.3. CAS No. 37340-58-2. Mole weight: mol wt ~100 kDa. Activity: 6.0 U/mg-solid or more. Storage: -20°C. Form: Lyophilized powder containing sugars and EDTA as stabilizers. Source: Actinobacillus sp. Creatine amidinohydrolase; creatinase; 37340-58-2; EC 3.5.3.3. Cat No: NATE-0160.
O-O-Dibenzyl-(-)-actinonin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: O-O-DIBENZYL-(-)-ACTINONIN;N4-Benzyloxy-N1-[1-(2-(S)-benzyloxy-methyl-pyrrolidine-1-carbonyl)-2-(S)-methyl-propyl]-2-(R)-pentylsuccinamide. Product Category: Heterocyclic Organic Compound. Appearance: Colourless Solid. CAS No. 460754-33-0. Molecular formula: C33H47N3O5. Mole weight: 565.74338. Product ID: ACM460754330. Alfa Chemistry ISO 9001:2015 Certified.