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1kg Pack Size. Group: Analytical Reagents, Diagnostic Raw Materials. Formula: C. CAS No. 7440-44-0. Prepack ID 90021896-1kg. Molecular Weight 12.01. See USA prepack pricing.
Active Carbon (Granulate 1-2 mm)
100g Pack Size. Group: Analytical Reagents, Biochemicals, Building Blocks, Organics. Formula: C. CAS No. 7440-44-0. Prepack ID 90025254-100g. Molecular Weight 12.01. See USA prepack pricing.
Palladium (on active carbon,
Palladium (on active carbon. Group: Biochemicals. Grades: Highly Purified. CAS No. 7440-5-3. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences.
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1-Chloroethylcyclohexyl-d11 Carbonate
1-Chloroethylcyclohexyl-d11 Carbonate is used in the synthesis of Candesartan Cilexetil-d11 (C175582), the labeled analogue of Candesartan Cilexetil (C175580), an ester prodrug; hydrolized in vivo to the active carboxylic acid. Used in treatment of congestive heart failure. Antihypertensive. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C9H4D11ClO3, Molecular Weight: 217.73. US Biological Life Sciences.
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1-Chloroethyl Isopropyl-d7 Carbonate
1-Chloroethyl Isopropyl-d7 Carbonate is an intermediate in the synthesis of Cefpodoxime Proxetil-d7 (C243862). Cefpodoxime Proxetil-d7 is the labelled form of Cefpodoxime Proxetil (C243860), an antibacterial. Cefpodoxime Proxetil is a broad spectrum, orally absorbed third generation cephalosporin, ester prodrug of the active free acid metabolite, Cefpodoxime (C243850). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C6H4D7ClO3, Molecular Weight: 173.65. US Biological Life Sciences.
Worldwide
1-Iodoethyl Isopropyl-d7 Carbonate
1-Iodoethyl Isopropyl-d7 Carbonate is an intermediate in the synthesis of Cefpodoxime Proxetil-d7 (C243862). Cefpodoxime Proxetil-d7 is the labelled form of Cefpodoxime Proxetil (C243860), an antibacterial. Cefpodoxime Proxetil is a broad spectrum, orally absorbed third generation cephalosporin, ester prodrug of the active free acid metabolite, Cefpodoxime (C243850). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C6H4D7IO3, Molecular Weight: 265.1. US Biological Life Sciences.
(1R, 4R) -4-[[ (1, 1-Dimethylethoxy) carbonyl]amino]-2-cyclopentene-1-carboxylic Acid Methyl Ester is an intermediate in synthesizing trans-Abacavir Dihydrochloride (A104995), which is an impurity of Abacavir. Abacavir (A104990) is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Group: Biochemicals. Grades: Highly Purified. CAS No. 168958-19-8. Pack Sizes: 10mg, 25mg. Molecular Formula: C12H19NO4. US Biological Life Sciences.
An optically active resolving agent. Group: Biochemicals. Alternative Names: [1S]-3-Oxo-4, 7, 7-trimethyl-2-oxabicyclo[2. 2. 1]heptane-1-carbonyl Chloride. Grades: Highly Purified. Pack Sizes: 5g. US Biological Life Sciences.
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2-(2-(2-Aminoethoxy)ethoxy)acetic acid
H2N-PEG2-CH2COOH belongs to a polyethylene glycol (PEG) linker covalently bound to E3 Ligase binding group (E3LB) and protein binding group (PB). H2N-PEG2-CH2COOH is a PEG derivative containing an amino group with a terminal carboxylic acid. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. PEG Linkers may be useful in the development of antibody drug conjugates and PROTACs. Synonyms: Amino-PEG2-CH2CO2H; Amino-PEG2-CH2COOH; Amino-PEG2-acetic acid. Grades: ≥95%. CAS No. 134978-97-5. Molecular formula: C6H13NO4. Mole weight: 163.17.
2- [2-Methoxy-4- [ [ [ (2-methylphenyl) sulfonyl] amino] carbonyl] phenyl] methyl] Zafirlukast is an impurity of Zafirlukast (Z125000); a potent, selective and orally active cysteinyl leukotriene type 1 receptor antagonist. Also used as an antiasthmatic. Group: Biochemicals. Grades: Highly Purified. CAS No. 1160235-26-6. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C47H48N4O10S2, Molecular Weight: 893.03. US Biological Life Sciences.
2- [2-Methoxy-4- [ [ [ (2-methylphenyl) sulfonyl] amino] carbonyl] phenyl] methyl] Zafirlukast-d3 is the isotope labelled analog of 2- [2-Methoxy-4- [ [ [ (2-methylphenyl) sulfonyl] amino] carbonyl] phenyl] methyl] Zafirlukast (M265710); an impurity of Zafirlukast (Z125000) which is a potent, selective and orally active cysteinyl leukotriene type 1 receptor antagonist. Also used as an antiasthmatic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C47H45D3N4O10S2, Molecular Weight: 896.05. US Biological Life Sciences.
2-Acetamido-3,4,6-tri-O-acetyl-1-O-(N-Cbz-6-aminohexyl)-2-deoxy-b-D-galactopyranose is a substantial chemical entity that exhibits immense significance in the biomedical research realm. This versatile compound serves as an active constituent in the bio-synthesis of glycosidase inhibitors, investigating glycosylation and glycoprotein metabolism in various malignant, diabetic and infectious disorders, and as a substrate for synthesizing carbohydrate-based therapeutics. The intricate composition of the chemical is a subject of intense interest among researchers, making it a valuable addition in the scientific community. Synonyms: (2R, 3R, 4R, 5R, 6R) -5-Acetamido-2- (acetoxymethyl) -6- ( (6- ( ( (benzyloxy) carbonyl) amino) hexyl) oxy) tetrahydro-2H-pyran-3, 4-diyl diacetate; [ (2R, 3R, 4R, 5R, 6R) -5-Acetamido-3, 4-diacetyloxy-6-[6- (phenylmethoxycarbonylamino) hexoxy]oxan-2-yl]methyl acetate; Carbamic acid, N-[6-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-beta-D-galactopyranosyl]oxy]hexyl]-, phenylmethyl ester; MFCD30489047; SCHEMBL1389482; BS-51431; CS-0226116; D96146; (2R, 3R, 4R, 5R, 6R) -5-Acetamido-2- (acetoxymethyl) -6- ( (6- ( ( (benzyloxy) carbonyl) amino) hexyl) oxy) tetrahydro-2H-pyran-3, 4-diyldiacetate; Carbamic acid, N-[6-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-|A-D-galactopyranosyl]oxy]hexyl]-, phenylmethyl ester; N-[6-[[3,4,6-Tri-O-acetyl-2-(acetylamino)-2-deoxy-beta-D-galactopyranosyl]oxy]hexyl]carbamic acid phenylmethyl ester. CAS No. 159173-77-0. Molecular formula: C28H40N2O11. Mole weight: 580.62.
2-Desaminosulfonyl 3-Aminosulfonyl Dorzolamide
2-Desaminosulfonyl 3-Aminosulfonyl Dorzolamide is a useful synthetic compound. Also, it is derived from (4R,6S)-5,6-Dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol 7,7-Dioxide (T344510), which is an analog of topically-active carbonic anhydrase inhibitor MK-507, commonly known Dorzolamide (D535100). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2mg. Molecular Formula: C10H16N2O4S3. US Biological Life Sciences.
2-Desaminosulfonyl 3-Aminosulfonyl N-Acetyl Dorzolamide is an intermediate in the synthesis of 2-Desaminosulfonyl 3-Aminosulfonyl Dorzolamide (D288235), which is derived from (4R,6S)-5,6-Dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol 7,7-Dioxide (T344510), which is an analog of topically-active carbonic anhydrase inhibitor MK-507, commonly known Dorzolamide (D535100). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C12H18N2O5S3. US Biological Life Sciences.
(2E) -6-[[ (1, 1-Dimethylethoxy) carbonyl]amino]-2-hexenoic Acid is an intermediate in the synthesis of (E)-6-Amino-2-hexenoic Acid, used in the preparation of anti-collagenase active agent. Group: Biochemicals. Alternative Names: (E) -6-[[ (1, 1-Dimethylethoxy) carbonyl]amino]-2-hexenoic Acid. Grades: Highly Purified. CAS No. 145119-17-1. Pack Sizes: 250mg. Molecular Formula: C??H??NO?, Molecular Weight: 229.27. US Biological Life Sciences.
(2E) -6-[[ (1, 1-Dimethylethoxy) carbonyl]amino]-2-hexenoic Acid Ethyl Ester is an intermediate in the synthesis of (E)-6-Amino-2-hexenoic Acid (A609990), used in the preparation of anti-collagenase active agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 1008751-73-2. Pack Sizes: 50mg, 250mg. Molecular Formula: C13H23NO4. US Biological Life Sciences.
Worldwide
2-?Hydroxyethyl-d4 Benzoate
2-?Hydroxyethyl-d4 Benzoate is a labelled analogue of 2-?Hydroxyethyl Benzoate (E917525), a reagent that can be used as an intermediate in a variety of chemical and biochemical reactions. It is used as an intermediate in the preparation of 1,2-Ethanediol Disodium Salt (E890125), which is the result of the nucleophilic attack on its carbonyl group. It can be also used as an intermediate in synthesizing Acyclovir-d4, an orally active acyclic labelled nucleoside with inhibitory activity towards several herpes viruses. Antiviral. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C9H6D4O3. US Biological Life Sciences.
[2R-[2α(S*),4 β ]]-4-[[ (2, 2-Dimethyl-1-oxopropoxy) methoxy]carbonyl]-α -[[ (hexahydro-1H-azepin-1-yl) methylene]amino]-5, 5-dimethyl-2-thiazolidineacetic Acid is an impurity of Pivmecillinam (P550700), an orally active prodrug of Amdinocillin (A576300), an broad spectrum penicillin antibiotic that binds specifically to penicillin binding protein 2. Group: Biochemicals. Grades: Highly Purified. CAS No. 72584-25-9. Pack Sizes: 1mg, 5mg. Molecular Formula: C21H35N3O6S, Molecular Weight: 457.58. US Biological Life Sciences.
Pivmecillinam EP Impurity B is an impurity of Pivmecillinam, which is an orally active prodrug of the broad-spectrum penicillin antibiotic Mecillinam. Synonyms: Pivmecillinam Impurity B; [2R-[2α(S*),4β]]-4-[[(2,2-Dimethyl-1-oxopropoxy)methoxy]carbonyl]-α-[[(hexahydro-1H-azepin-1-yl)methylene]amino]-5,5-dimethyl-2-thiazolidineacetic Acid; 2-Thiazolidineacetic acid, 4-[[(2,2-dimethyl-1-oxopropoxy)methoxy]carbonyl]-α-[[(hexahydro-1H-azepin-1-yl)methylene]amino]-5,5-dimethyl-, [2R-[2α(S*),4β]]-. CAS No. 72584-25-9. Molecular formula: C21H35N3O6S. Mole weight: 457.58.
3,4-Ethylenedioxythiophene
3,4-Ethylenedioxythiophene (EDOT) is an electro-active conductive monomer with a thiol group that combines an electron donor and electron acceptor in a donor-acceptor-donor arrangement. Monomer used in the synthesis of conducting polymers. Uses: Edot can be polymerized to form poly(3,4-ethylenedioxythiophene) (pedot) for use as an electrochromic polymer (ec) based coating for a variety of s like solid state organic electrochemical supercapacitors (oescs), electrochromic devices (ecds), and carbon nanotubes (cnts) based electrochemical devices for diabetes monitoring. it can be used: as a reductant in a one-pot synthesis of gold nanoparticles from haucl4 (254169). as a starting material used in palladium-catalyzed mono- and bis-arylation reactions. in the synthesis of conjugated polymers and copolymers, with potential optical s. Group: Electroluminescence materials synthetic tools and reagents polymers. Alternative Names: EDOT. CAS No. 126213-50-1. Pack Sizes: Packaging 10 g in glass bottle. Product ID: 2,3-Dihydrothieno[3,4-b][1,4]dioxine. Molecular formula: 142.18. Mole weight: C6H6O2S. C1COC2=CSC=C2O1. InChI=1S/C6H6O2S/c1-2-8-6-4-9-3-5 (6)7-1/h3-4H, 1-2H2. GKWLILHTTGWKLQ-UHFFFAOYSA-N. 95%+.
3-Chlorophenol
3-Chlorophenol is a halophenol with antifungal activity. 3-Chlorophenol is commonly used as a building block in the preparation of variety of biologically active compounds. Studies suggest that 3-Chlorophenol can be used in the regeneration of vegetal activated carbons. Group: Biochemicals. Alternative Names: 3-Hydroxychlorobenzene; NSC 59700; m-Chlorophenic Acid; m-Chlorophenol. Grades: Highly Purified. CAS No. 108-43-0. Pack Sizes: 50g. US Biological Life Sciences.
Worldwide
4'-Bromo-4-cyanobiphenyl
4'-Bromo-4-cyanobiphenyl is a biologically active agent that serves as a crucial constituent in the synthesis of medicinal drugs utilized in the remedy of different ailments, including cancer, autoimmune disorders, and arthritis. Its versatile chemical properties allow for enhanced efficacy in drug development, making it a valuable pharmaceutical intermediate. Synonyms: 4'-bromo-[1,1'-Biphenyl]-4-carbonitrile. CAS No. 57774-35-3. Molecular formula: C13H8BrN. Mole weight: 258.11.
The enzyme, characterized from yeast and mammals, catalyses the hydroxylation of carbon 2 of long- or very-long-chain fatty acids attached to (4R)-4-hydroxysphinganine during de novo ceramide synthesis. The enzymes from yeast and from mammals contain an N-terminal cytochrome b5 domain that acts as the direct electron donor to the desaturase active site. The newly introduced 2-hydroxyl group has R-configuration. cf. EC 1.14.18.7, dihydroceramide fatty acyl 2-hydroxylase. Group: Enzymes. Synonyms: FA2H (gene name); SCS7 (gene name). Enzyme Commission Number: EC 1.14.18.6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0968; 4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase; EC 1.14.18.6; FA2H (gene name); SCS7 (gene name). Cat No: EXWM-0968.
7-(2,2,2-Trichloroethyloxycarbonyl)-10-deacetylbaccatin III
7-(2,2,2-Trichloroethyloxycarbonyl)-10-deacetylbaccatin III is an impurity of Cephalomannine, which is an active anticancer agent extracted from Taxus yunnanensis with antitumor effects on tumors in mice. Synonyms: Cephalomannine Impurity 4; [(1S, 2S, 3R, 4S, 7R, 9S, 10S, 12R, 15S)-4-acetyloxy-1, 12, 15-trihydroxy-10, 14, 17, 17-tetramethyl-11-oxo-9-(2, 2, 2-trichloroethoxycarbonyloxy)-6-oxatetracyclo[11.3.1.03, 10.04, 7]heptadec-13-en-2-yl] benzoate; (2α, 5β, 7β, 10β, 13α)-4-Acetoxy-1, 10, 13-trihydroxy-9-oxo-7-{[(2, 2, 2-trichloroethoxy)carbonyl]oxy}-5, 20-epoxytax-11-en-2-yl benzoate. Grades: ≥95%. CAS No. 114915-19-4. Molecular formula: C32H37Cl3O12. Mole weight: 719.99.
A cobalt complex used as a chiral selector of PVC membrane electrode. A highly active catalysts for the copolymerization of propylene oxide and carbon dioxide. (R,R)-(-)-N,N?-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine (B431500) derivative, a ligand used in the preparation of Jacobsen's catalyst. Group: Biochemicals. Alternative Names: (Acetato-κ O) [[2, 2'-[1, 2-cyclohexanediylbis[ (nitrilo-κ N) methylidyne]]bis[4, 6-bis (1, 1-dimethylethyl) phenolato-κ O]] (2-) ]-, [SP-5-13-(1R-trans)]-cobalt. Grades: Highly Purified. CAS No. 201870-82-8. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
acetoacetate decarboxylase
Acetoacetate decarboxylase (AAD or ADC) is an enzyme involved in both the ketone body production pathway in humans and other mammals, and solventogenesis in bacteria. Acetoacetate decarboxylase plays a key role in solvent production by catalyzing the decarboxylation of acetoacetate, yielding acetone and carbon dioxide. This enzyme has been of particular interest because it is a classic example of how pKa values of ionizable groups in the enzyme active site can be significantly perturbed. Specifically, the pKa value of lysine 115 in the active site is unusually low, allowing for the formation of a Schiff base intermediate and catalysis. Group: Enzymes. Synonyms: acetoacetic acid decarboxylase; acetoacetate carboxy-lyase. Enzyme Commission Number: EC 4.1.1.4. CAS No. 9025-03-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4784; acetoacetate decarboxylase; EC 4.1.1.4; 9025-03-0; acetoacetic acid decarboxylase; acetoacetate carboxy-lyase. Cat No: EXWM-4784.
Active Charcoal Mask
Active Charcoal Mask. Product ID: CDC10-0632. Category: Black Mask. Product Keywords: Cosmetic Ingredients; Cosmetic packaging material; Active Charcoal Mask; CDC10-0632; Black Mask; Activated carbon fibers.
acyl-[acyl-carrier-protein] 6-desaturase
The enzyme, characterized from the endosperm of the plant Thunbergia alata (black-eyed Susan vine), introduces a cis double bond at carbon 6 of several saturated acyl-[acp]s. It is most active with palmitoyl-[acp] (16:0), but can also act on myristoyl-[acp] (14:0) and stearoyl-[acp] (18:0). The position of the double bond is determined by its distance from the carboxyl end of the fatty acid. Group: Enzymes. Synonyms: DELTA6 palmitoyl-ACP desaturase; DELTA6 16:0-ACP desaturase. Enzyme Commission Number: EC 1.14.19.26. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0989; acyl-[acyl-carrier-protein] 6-desaturase; EC 1.14.19.26; DELTA6 palmitoyl-ACP desaturase; DELTA6 16:0-ACP desaturase. Cat No: EXWM-0989.
acyl-CoA 6-desaturase
An iron protein. The enzyme introduces a cis double bond at carbon 6 of acyl-CoAs. It is a front-end desaturase, introducing the new double bond between a pre-existing double bond and the carboxyl-end of the fatty acid. The human enzyme has a broad substrate range. It also acts on palmitoyl-CoA, generating sapienoyl-CoA, and on (9Z,12Z,15Z,18Z,21Z)-tetracosa-9,12,15,18,21-pentaenoyl-CoA, converting it to (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosa-6,9,12,15,18,21-hexaenoyl-CoA as part of a pathway that produces docosahexaenoate. The enzyme contains a cytochrome b5 domain that is assumed to act in vivo as the electron donor to the active site of the desaturase. Group: Enzymes. Synonyms: Δ6-desatu. Enzyme Commission Number: EC 1.14.19.3. CAS No. 9082-66-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0993; acyl-CoA 6-desaturase; EC 1.14.19.3; 9082-66-0; Δ6-desaturase; Δ6-fatty acyl-CoA desaturase; Δ6-acyl CoA desaturase; fatty acid Δ6-desaturase; fatty acid 6-desaturase; linoleate desaturase; linoleic desaturase; linoleic acid desaturase; linoleoyl CoA desaturase; linoleoyl-coenzyme A desaturase; long-chain fatty acid Δ6-desaturase; linoleoyl-CoA,hydrogen-donor:oxygen oxidoreductase; linoleoyl-CoA desaturase; FADS2 (gene name). Cat No: EXWM-0993.
acyl-CoA (8-3)-desaturase
The enzyme introduces a cis double bond at carbon 5 of acyl-CoAs that contain a double bond at position 8. The enzymes from algae, mosses, mammals and the protozoan Leishmania major catalyse the desaturation of dihomo-γ-linoleate [(8Z,11Z,14Z)-icosa-8,11,14-trienoate] and (8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoate to generate arachidonate and (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoate, respectively. The enzyme contains a cytochrome b5 domain that acts as the direct electron donor to the desaturase active site and does not require an external cytochrome. cf. EC 1.14.19.37, acyl-CoA 5-desaturase. Group: Enzymes. Synonyms: FADS1 (gene name); acyl-CoA 5-desaturase (methylene-interrupted). Enzyme Commission Number: EC 1.14.19.44. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1009; acyl-CoA (8-3)-desaturase; EC 1.14.19.44; FADS1 (gene name); acyl-CoA 5-desaturase (methylene-interrupted). Cat No: EXWM-1009.
Acyl-Coenzyme A Dehydrogenase 8 from Human, Recombinant
Acyl CoA dehydrogenase is the enzymeused to catalyzethe first step of β-oxidationin Fatty acid metabolism. Acyl-coenzyme A (CoA) dehydrogenases (ACADs) are a family of mitochondrial enzymes that catalyze the first dehydrogenation step in the bets-oxidation of fatty acyl-CoA derivatives. Several human ACADs exist and all ACADs catalyze the same initial dehydrogenation of the substrate at the beta-carbon atom and require electron transfer flavoprotein as an alectron acceptor. The predicted 415-amino acid ACAD8 protein contains many of the residues conserved in most other ACADs, including an active site glutamic acid residue and residues important for tetramer f...mber 8 mitochondrial; ACAD-8; Isobutyryl-CoA dehydrogenase; Activator-recruited cofactor 42 kDa component; ARC42; FLJ22590. Purity: Greater than 95.0% as determined by SDS-PAGE. ACAD-8. Mole weight: 47.7 kDa. Stability: ACAD8 although stable at 4°C for 1 week, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. Appearance: Sterile Filtered clear solution. Source: E. coli. Species: Human. Acyl-CoA dehydrogenase family member 8 mitochondrial; ACAD-8; Isobutyryl-CoA dehydrogenase; Activator-recruited cofactor 42 kDa component; ARC42; FLJ22590. Cat No: NATE-0801.
acyl-lipid (11-3)-desaturase
The enzyme, characterized from the protist Euglena gracilis and the microalga Rebecca salina, introduces a cis double bond at the 8-position in 20-carbon fatty acids that are incorporated into a glycerolipid and have an existing Δ11 desaturation. The enzyme is a front-end desaturase, introducing the new double bond between the pre-existing double bond and the carboxyl-end of the fatty acid. It contains a cytochrome b5 domain that acts as the direct electron donor to the active site of the desaturase, and does not require an external cytochrome. Involved in alternative pathways for the biosynthesis of the polyunsaturated fatty acids arachidonate and icosapentaenoate. Group: Enzymes. Synonyms: acyl-lipid 8-desaturase; Δ8 fatty acid desaturase; Δ8-desaturase; Δ8-fatty-acid desaturase; efd1 (gene name); D8Des (gene name); phytosphinganine,hydrogen donor:oxygen Δ. Enzyme Commission Number: EC 1.14.19.4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1004; acyl-lipid (11-3)-desaturase; EC 1.14.19.4; acyl-lipid 8-desaturase; Δ8 fatty acid desaturase; Δ8-desaturase; Δ8-fatty-acid desaturase; efd1 (gene name); D8Des (gene name); phytosphinganine,hydrogen donor:oxygen Δ8-oxidoreductase (incorrect); SLD. Cat No: EXWM-1004.
acyl-lipid (7-3)-desaturase
The enzymes from several algae introduce a cis double bond at the 4-position in 22-carbon polyunsaturated fatty acids that contain a Δ7 double bond. The enzyme from the fresh water alga Chlamydomonas reinhardtii acts on the 16 carbon fatty acid (7Z,10Z,13Z)-hexadeca-7,10,13-trienoate. The enzyme contains an N-terminal cytochrome b5 domain that acts as the direct electron donor to the active site of the desaturase, and does not require an external cytochrome. Group: Enzymes. Synonyms: D4Des (gene name); des1 (gene name); CrΔ4FAD (gene name); acyl-lipid 4-desaturase. Enzyme Commission Number: EC 1.14.19.31. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0995; acyl-lipid (7-3)-desaturase; EC 1.14.19.31; D4Des (gene name); des1 (gene name); CrΔ4FAD (gene name); acyl-lipid 4-desaturase. Cat No: EXWM-0995.
acyl-lipid (8-3)-desaturase
The enzyme, which has been characterized from multiple organisms including the moss Physcomitrella patens, the marine microalga Rebecca salina, and the filamentous fungus Mortierella alpina, introduces a cis double bond at the 5-position in 20-carbon polyunsaturated fatty acids incorporated in a glycerolipid that contain a Δ8 double bond. The enzyme contains a cytochrome b5 domain that acts as the direct electron donor to the active site of the desaturase, and does not require an external cytochrome. Group: Enzymes. Synonyms: acyl-lipid 5-desaturase; Δ5-fatty-acid desaturase; DES5 (gene name); D5des (gene name); FADS1. Enzyme Commission Number: EC 1.14.19.30. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0994; acyl-lipid (8-3)-desaturase; EC 1.14.19.30; acyl-lipid 5-desaturase; Δ5-fatty-acid desaturase; DES5 (gene name); D5des (gene name); FADS1. Cat No: EXWM-0994.
acyl-lipid (9-3)-desaturase
The enzyme, characterized from the moss Physcomitrella patens and the plant Borago officinalis (borage), introduces a cis double bond at carbon 6 of several acyl-lipids that contain an existing Δ9 cis double bond. The enzyme contains a cytochrome b5 domain that acts as the electron donor for the active site of the desaturase. Group: Enzymes. Synonyms: acyl-lipid 6-desaturase; Δ6-desaturase; DES6 (gene name). Enzyme Commission Number: EC 1.14.19.47. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1012; acyl-lipid (9-3)-desaturase; EC 1.14.19.47; acyl-lipid 6-desaturase; Δ6-desaturase; DES6 (gene name). Cat No: EXWM-1012.
acyl-lipid ω-(9-4) desaturase
The enzyme, characterized from the green alga Chlamydomonas reinhardtii, is a front-end desaturase that introduces a cis double bond in ω9 unsaturated C18 or C20 fatty acids incorporated into lipids, at a position 4 carbon atoms from the existing ω9 bond, towards the carboxy end of the fatty acid (at the ω13 position). When acting on 20:2Δ(11,14) and 20:3Δ(11,14,17) substrates it introduces the new double bond between carbons 7 and 8. The enzyme contains a cytochrome b5 domain that acts as the direct electron donor for the active site of the desaturase. Group: Enzymes. Synonyms: acyl-lipid ω-13 desaturase; acyl-lipid 7-desaturase (ambiguous). Enzyme Commission Number: EC 1.14.19.12. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0974; acyl-lipid ω-(9-4) desaturase; EC 1.14.19.12; acyl-lipid ω-13 desaturase; acyl-lipid 7-desaturase (ambiguous). Cat No: EXWM-0974.
AD-mix-α
AD-mix-α is a mixture of organic compounds, commonly used to distinguish and identify asymmetric carbon atoms in chiral compounds. It consists of compounds containing catalytically active metals and chiral ligands. AD-mix-α is widely used in various organic synthesis reactions, such as hydrogenation, addition, and carbonylation reactions, to increase yield and reduce the formation of side reaction products. Although it has no direct application in the medical field, it plays an important role in the pharmaceutical industry and chemical research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 153130-59-7. Pack Sizes: 1 g; 5 g. Product ID: HY-24312.
AM-206
AM-206 is a bio-active chemical but no detailed data has been published yet. Synonyms: AM-206; AM 206; AM206; 3-Pyridineacetic acid, 5- (2- ( (ethyl ( (phenylmethoxy) carbonyl) amino) methyl) -4- (trifluoromethyl) phenyl) -, sodium salt (1:1); UNII-NCZ7ZWF0CR;1219935-54-2 (AM-206 free acid). Grades: 98%. CAS No. 1224977-86-9. Molecular formula: C25H22F3N2NaO4. Mole weight: 494.44.
Ambuic acid
Ambuic acid is a cyclohexanone originally isolated from Pestalotiopsis and Monochaetia species. Antibiotic medications are widely used in the treatment and prevention of such infections. They may either kill or inhibit the growth of bacteria. It is active against P. ultimum (MIC = 7.5 μg/ml) and inhibits the growth of a variety of other phytopathogenic fungi. Ambuic acid inhibits the biosynthesis of cyclic peptides involved in quorum sensing, including gelatinase biosynthesis-activating pheromone (GBAP). Synonyms: (+)-Ambuic acid; (2E,5R,6R,7R,8E,10E)-2-Methyl-5,9-carbonyl-5,6-epoxy-7-hydroxy-8-(hydroxymethyl)-2,8,10-hexadecatrienoic acid. Grades: ≥95%. CAS No. 340774-69-8. Molecular formula: C19H26O6. Mole weight: 350.41.
AMG-009
AMG-009 is an orally active, small molecule dual D prostanoid(DP) receptor and chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2) antagonist. It was in preclinical development for the treatment of asthma and allergic rhinitis. It was developed by Amgen Inc. Uses: Amg-009 was in preclinical development for the treatment of asthma and allergic rhinitis. Synonyms: AMG-009; AMG 009; AMG009; 2-[4-[4- (Butylcarbamoyl) -2-[ (2, 4-dichlorophenyl) sulfonylamino]phenoxy]-3-methoxyphenyl]acetic acid;AMG009;Benzeneacetic acid, 4- (4- ( (butylamino) carbonyl) -2- ( ( (2, 4-dichlorophenyl) sulfonyl) amino) phenoxy) -3-methoxy-. Grades: >98 %. CAS No. 1027847-67-1. Molecular formula: C26H26Cl2N2O7S. Mole weight: 581.46.
Amino-PEG3-t-butyl acetate
NH2-PEG3-C1-Boc is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 5 can be used in the synthesis of a series of PROTACs. NH2-PEG3-C1-Boc is a PEG derivative containing an amino group with a t-butyl protected carboxyl group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions. PEG Linkers may be useful in the development of antibody drug conjugates, PROTACs and drug delivery methods. Synonyms: NH2-PEG3-C1-Boc; PROTAC Linker 5; Amino-PEG3-CH2CO2-t-butyl ester; H2N-PEG3-CH2COOtBu; Acetic acid, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester. Grades: >95%. CAS No. 189808-70-6. Molecular formula: C12H25NO5. Mole weight: 263.33.
Apimostinel
Apimostinel is a selective partial agonist of an allosteric site of the glycine site of the NMDA receptor complex under investigation by Naurex. Its mechanism of action and effects are similar to those of rapastinel. But Apimostinel is 100-fold more potent by weight and, unlike rapastinel (which must be administered via intravenous injection), is orally-active. Phase II clinical trials for the treatment of Major depressive disorder is on-going. Uses: Major depressive disorder. Synonyms: NRX-1074; NRX 1074; NRX1074; AGN-241660; AGN241660; AGN 241660. Apimostinel;(2R)-1-[(2S)-1-[(2S,3R)-2-amino-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]-N-[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]-2-benzylpyrrolidine-2-carboxamide. Grades: 98%. CAS No. 1421866-48-9. Molecular formula: C25H37N5O6. Mole weight: 503.60.
Azido-PEG4-Amine
N3-PEG4-C2-NH2 is a polyethylene glycol (PEG)-based PROTAC linker. N3-PEG4-C2-NH2 can be used in the synthesis of a series of PROTACs. N3-PEG4-C2-NH2 is a PEG derivative containing an amino group with an azide group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. Synonyms: 14-Azido-3,6,9,12-tetraoxatetradecan-1-amine; O-(2-Aminoethyl)-O'-(2-azidoethyl)triethylene Glycol; N3-PEG4-C2-NH2; N3-PEG4-CH2CH2NH2; 14-Amino-3,6,9,12-tetraoxatetradecanyl Azide; 1-Amino-14-azido-3,6,9,12-tetraoxatetradecane. Grades: ≥95%. CAS No. 951671-92-4. Molecular formula: C10H22N4O4. Mole weight: 262.31.
Bacitracin B1
It is produced by the strain of Bacillus sp. It is a highly purified form of bacitracin B1 and a compound present in standard grade bacitracin. It together with bacitracin B2 is slightly less active than bacitracin A. Synonyms: Bacitracin F, 1-[N-[[2-(1-amino-2-methylbutyl)-4,5-dihydro-4-thiazolyl]carbonyl]-L-leucine]-6-L-valine-; Bacitracin B1a; L-Asparagine, N-[[2-(1-amino-2-methylbutyl)-4,5-dihydro-4-thiazolyl]carbonyl]-L-leucyl-D-a-glutamyl-L-isoleucyl-L-lysyl-D-ornithyl-L-valyl-D-phenylalanyl-L-histidyl-D-a-aspartyl-, cyclic (10,4)-peptide, [4R-[2(1S*,2S*),4R*]]-; Unk-Leu-D-Glu-Ile-Lys(1)-D-Orn-Val-D-Phe-His-D-Asp-Asn-(1). Grades: ≥98.0% by HPLC. CAS No. 57762-79-5. Molecular formula: C65H101N17O16S. Mole weight: 1408.66.
BAY-721973
BAY-721973 is a bio-active chemical,but few detailed information has been published yet. Synonyms: BAY-721973; BAY 721973; BAY721973; Sorafenib metabolite M3; UNII-83F1Z938Q0; 4- (4- ( ( ( (4-chloro-3- (trifluoromethyl) phenyl) amino) carbonyl) amino) phenoxy) -N- (hydroxymethyl) -2-Pyridinecarboxamide. Grades: 98%. CAS No. 1380310-94-0. Molecular formula: C21H16ClF3N4O4. Mole weight: 480.83.
BAY 85-8501
This active molecular is a highly selective neutrophil elastase inhibitor.IC50 for HNE is 0.065 nM, LipE is 7.2. BAY 85-8501 was being tested in clinical studies for the treatment of pulmonary diseases. In Feb 2013, Phase-II clinical trials in Bronchiectasis in Spain were on going. In Mar 2013, Phase-II clinical trials in Bronchiectasis in France, Germany and Italy were on going. In Jun 2014, Bayer completed a phase IIa trial in Bronchiectasis in United Kingdom, Spain, France, Germany and Italy. Uses: The treatment of pulmonary diseases. Synonyms: BAY 85-8501; BAY85-8501; BAY-85-8501; BAY 858501; BAY858501; BAY-858501. (S)-4-(4-cyano-2-(methylsulfonyl)phenyl)-3,6-dimethyl-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydropyrimidine-5-carbonitrile. Grades: 98%. CAS No. 1161921-82-9. Molecular formula: C22H17F3N4O3S. Mole weight: 474.46.
benzil reductase [(R)-benzoin forming]
The enzyme from the bacterium Xanthomonas oryzae is able to reduce enantioselectively only one of the two carbonyl groups of benzil to give optically active (R)-benzoin. Group: Enzymes. Enzyme Commission Number: EC 1.1.1.321. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0234; benzil reductase [(R)-benzoin forming]; EC 1.1.1.321. Cat No: EXWM-0234.
Bis(4-nitrophenyl)carbonate
Bis(4-nitrophenyl) Carbonate is used for synthesis of 4-nitrophenyl active esters of amino acids. It can also be used in the preparation of symmetrical and unsymmetrical ureas. Synonyms: Carbonic Acid Bis(4-nitrophenyl) Ester; 4,4'-Dinitrodiphenyl Carbonate; Bis(p-nitrophenyl) Carbonate; Di-4-nitrophenyl Carbonate; Di-p-nitrophenyl Carbonate; NSC 1730; NPC; p,p'-Dinitrodiphenylcarbonate; p-nitrophenylcarbonate; SCHEMBL26374. Grades: 98 % (HPLC). CAS No. 5070-13-3. Molecular formula: C13H8N2O7. Mole weight: 304.21.
BMS-275183
BMS-275183 is an oral C-4 methyl carbonate analogue of paclitaxel that has the same mechanism of action, stabilization of tubulin polymerization. BMS-275183 given p.o. was active in a human, hormone-dependent, prostate tumor model, CWR-22, and just as effective as anti-androgen chemotherapy. BMS-275185 is lack of evidence of clinical benefit with the occurrence of two fatal events of neutropenic sepsis. Synonyms: BMS 275183; BMS275183. CAS No. 355113-98-3. Molecular formula: C43H59NO16. Mole weight: 845.94.
Boc-3,4-dichloro-D-phenylalanine
Boc-3,4-dichloro-D-phenylalanine is used to prepare fluorinated β-aminoacyl 1,2,4-triazolo[4,3-a]piperazine amides as dipeptidyl peptidase IV inhibitors and antidiabetic agents. It is also used in the synthesis of N-[(R,R)-(E)-1-(3,4-dichlorobenzyl)-3-(2-oxoazepan-3-yl)carbamoyl]allyl-N-methyl-3,5-bis(trifluoromethyl)benzamide as a potent and orally active dual neurokinin NK1/NK2 receptor antagonist. Synonyms: Boc-D-Phe(3,4-DiCl)-OH; Boc-D-Phe(3,4-Cl2)-OH; (R)-Boc-2-amino-3-(3,4-dichlorophenyl)propionic acid; Boc-D-Phe(3,4-Cl2)-OH; (R)-2-((tert-Butoxycarbonyl)amino)-3-(3,4-dichlorophenyl)propanoic acid; D-Phenylalanine, 3,4-dichloro-N-[(1,1-dimethylethoxy)carbonyl]-; Boc-D-3,4-Dichlorophenylalanine; AK162594; N-BOC-3,4-DICHLORO-D-PHENYLALANINE. Grades: ≥ 98% (HPLC). CAS No. 114873-13-1. Molecular formula: C14H17Cl2NO4. Mole weight: 334.20.
Boc-β-cyclohexyl-L-alanine
Boc-β-cyclohexyl-L-alanine, is an Alanine derivative, that can be used as an intermediate in the synthesis of pharmaceutical and biologically active compounds, including inhibitors. It is used in the synthesis of a novel class of piperidine or morpholine-based renin inhibitors, and also for the preparation of Remikiren. Synonyms: Boc-L-Cha-OH; Boc-3-cyclohexyl-L-alanine; (S)-2-tert-Butoxycarbonylamino-3-cyclohexyl-propionic acid; Boc-Cha-OH; BOC-BETA-CYCLOHEXYL-ALA-OH; Boc-L-cyclohexylalanine; (S)-2-(tert-butoxycarbonylamino)-3-cyclohexylpropanoic acid; Cyclohexanepropanoic acid, a-[[(1,1-dimethylethoxy)carbonyl]amino]-,(aS)-; N-BOC-b-cyclohexylalanine; AK-76930; Boc-3-cyclohexyl-L-alanine; N-BOC-beta-cyclohexylalanine; Boc L Cha OH. Grades: 99%. CAS No. 37736-82-6. Molecular formula: C14H25NO4. Mole weight: 271.35.
C60 Pyrrolidine tris-acid
97%. Uses: C60 pyrrolidine tris-acid may be used as a cathode buffer layer in solar cells. it may be used as a wetting layer in an organic photovoltaics.cpta can be used as a cathodic buffer that forms a conductive layer between the active layer and the electrode layer for the fabrication of polymeric solar cells and perovskite based solar cells. Group: Carbon nano materials. Pack Sizes: 100 mg. Molecular formula: 909.76 g/mol.
Candesartan Cilexetil
Ester prodrug; hydrolized in vivo to the active carboxylic acid. Used in treatment of congestive heart failure. Antihypertensive. Group: Biochemicals. Alternative Names: 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid 1-[[ (Cyclohexyloxy) carbonyl]oxy]ethyl Ester; Atacand; Blopress; TCV 116. Grades: Highly Purified. CAS No. 145040-37-5. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
Capecitabine
Capecitabine is an oral proagent that is converted to its active metabolite, 5-FU, by thymidine phosphorylase. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-DEOXY-5-FLUOROCYTISINE;5-DEOXY-5-FLUORO-N-[(PENTYLOXY)CARBONYL]CYTIDINE;CAPECITABINE;RO-9-1978;pentyl [1-(3,4-dihydroxy-5-methyl-oxolan-2-yl)-5-fluoro-2-oxo-pyrimidin-4-yl]aminoformate;XELODA;Cpecitabine;5Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine, Ro-9-1978, Xeloda. Product Category: Inhibitors. Appearance: Solid. CAS No. 154361-50-9. Molecular formula: C15H22FN3O6. Mole weight: 359.35. Purity: 0.9987. Canonical SMILES: O[C@H]1[C@@H](O)[C@H](N2C=C(C(NC(OCCCCC)=O)=NC2=O)F)O[C@@H]1C. Product ID: ACM154361509. Alfa Chemistry ISO 9001:2015 Certified.
Capecitabine-d11
Capecitabine-d11 is the deuterium labeled Capecitabine. Capecitabine is an oral proagent that is converted to its active metabolite, 5-FU, by thymidine phosphorylase. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5'-DEOXY-5-FLUORO-N-[(PENTYLOXY)CARBONYL]CYTIDINE-D11;CAPECITABINE-D11. Product Category: Inhibitors. Appearance: Off-White Solid. CAS No. 1132662-08-8. Molecular formula: C15H11D11FN3O6. Mole weight: 372.43. Canonical SMILES: C[C@@H]1[C@H]([C@H]([C@H](N2C(N=C(C(F)=C2)NC(OC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O)=O)O1)O)O. Product ID: ACM1132662088. Alfa Chemistry ISO 9001:2015 Certified.
The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides. The enzyme from Escherichia coli has three separate active sites, which are connected by a molecular tunnel that is almost 100 ? in length. The amidotransferase domain within the small subunit of the enzyme hydrolyses glutamine to ammonia via a thioester intermediate. The ammonia migrates through the interior of the protein, where it reacts with carboxyphosphate to produce the carbamate intermediate. The carboxyphosphate intermediate is formed by the phosphorylation of hydrogencarbonate by ATP at a site contained within the N-terminal half of the large ... (gene name); CAD (gene name); hydrogen-carbonate:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating). Enzyme Commission Number: EC 6.3.5.5. CAS No. 37233-48-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5808; carbamoyl-phosphate synthase (glutamine-hydrolysing); EC 6.3.5.5; 37233-48-0; carbamoyl-phosphate synthetase (glutamine-hydrolysing); carbamyl phosphate synthetase (glutamine); carbamoylphosphate synthetase II; glutamine-dependent carbamyl phosphate synthetase; carbamoyl phosphate synthetase; CPS; carbon-dioxide:L-glutamine amido-ligase (ADP-forming, carbam
Carbobenzoxy-Pro-Lys-Phe-Y(Po2)-Ala-Pro-Ome
Carbobenzoxy-Pro-Lys-Phe-Y(Po2)-Ala-Pro-Ome is an intricate biomedical substance, finding utility in studying cancer and autoimmune ailments. It actively operates as a potent inhibitor, selectively targeting enzymes or pathways implicated in the advancement of such afflictions. Synonyms: Methyl N-{[(1R)-1-({1-[(benzyloxy)carbonyl]-L-prolyl-6-ammonio-L-norleucyl}amino)-2-phenylethyl](hydroxy)phosphoryl}-L-alanyl-L-prolinate. Molecular formula: C36H52N6O9P. Mole weight: 743.81.
Carbonic acid di-2-pyridyl ester
Carbonic acid di-2-pyridyl ester is used as a coupling agent in the esterification of carboxylic acids. Di-2-pyridyl carbonate is also used as a reagent to synthesize active carbonates and carbamates. Synonyms: DPC; 2-Pyridinol-2,2'-carbonate; 2-Pyridinol Carbonate; Bis(pyrid-2-yl) Carbonate; Bis(pyridin-2-yl) Carbonate; Di-2-pyridyl Carbonate; 2-Pyridinol, carbonate (2:1) (ester) (9CI); Carbonic acid, di-2-pyridyl ester (7CI,8CI). Grades: 98 % (HPLC). CAS No. 1659-31-0. Molecular formula: C11H8N2O3. Mole weight: 216.19.
Carbonic anhydrase from E. coli, recombinant
The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs relatively slowly in the absence of a catalyst. The active site of most carbonic anhydrases contains a zinc ion; they are therefore classified as metalloenzymes. Group: Enzymes. Synonyms: Carbonate dehydratase; CAN; yadF. Enzyme Commission Number: EC 4.2.1.1. Purity: > 95% by SDS-PAGE. Carbonic Anhydrase. Mole weight: This protein is fused with 6x His tag at N terminus and the protein has a calculated MW of 27 kDa (240aa). Activity: >1,000 pmol/min/ug. Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -70°C. Avoid repeated freezing and thawing cycles. Form: Liquid. Source: E. coli. Species: E. coli. carbonic anhydrases; carbonate dehydratases; EC 4.2.1.1; anhydrase; carbonate anhydrase; carbonic acid anhydrase; carboxyanhydrase; carbonic anhydrase A; carbonate hydro-lyase; CA; CAN; yadF. Cat No: NATE-1669.
Carbonic Anhydrase II from Bovine, Recombinant
The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs relatively slowly in the absence of a catalyst. The active site of most carbonic anhydrases contains a zinc ion; they are therefore classified as metalloenzymes. Carbonic anhydrase is a zinc-containing enzyme that catalyzes the reversible conversion of carbon dioxide to bicarbonate. one of its main physiological roles is to maintain the acid-base balance in blood and other tissues. lack of carbonic anhydrase results in carbonic anhydrase type ii defi...ns: Carbonic anhydrase is used to create carbon dioxide capture systems and to research various purification techniques. carbonic anhydrase is also used to study acid-base regulation in fish and carbonic anhydrase type ii deficiency syndrome. bovine carbonic anhydrase ii (ca II), has been widely used as a model protein in the investigation of the protein folding process. Group: Enzymes. Synonyms: carbonic anhydrases; carbonate dehydratases; EC 4.2.1.1; anhydrase; carbonate anhydrase; carbonic acid anhydrase; carboxyanhydrase; carbonic anhydrase A; carbonate hydro-lyase. Enzyme Commission Number: EC 4.2.1.1. CAS No. 9001-03-0. Purity: >90% by SDS-PAGE. Carbonic Anhydras
CCT244747
CCT244747 is a novel potent, highly selective, orally active ATP-competitive CHK1 inhibitor with potential anticancer activity. CCT244747 inhibited cellular CHK1 activity (IC(50) 29-170 nmol/L), significantly enhanced the cytotoxicity of several anticancer drugs, and abrogated drug-induced S and G(2) arrest in multiple tumor cell lines. CCT244747 represents the first structural disclosure of a highly selective, orally active CHK1 inhibitor and warrants further evaluation alone or combined with genotoxic anticancer therapies. Synonyms: CCT-244747; CCT 244747; 3-{[(2R)-1-(Dimethylamino)-2-propanyl]oxy}-5-{[4-methoxy-5-(1-methyl-1H-pyrazol-4-yl)-2-pyridinyl]amino}-2-pyrazinecarbonitrile; 3-[(1R)-2-(Dimethylamino)-1-methylethoxy]-5-[[4-methoxy-5-(1-methyl-1H-pyrazol-4-yl)-2-pyridinyl]amino]-2-pyrazinecarbonitrile; (R)-3-((1-(dimethylamino)propan-2-yl)oxy)-5-((4-methoxy-5-(1-methyl-1H-pyrazol-4-yl)pyridin-2-yl)amino)pyrazine-2-carbonitrile. Grades: ≥98%. CAS No. 1404095-34-6. Molecular formula: C20H24N8O2. Mole weight: 408.46.
CCT245737
CCT245737 is an orally bioactive CHK1 inhibitor (IC50 of 1.4 nM), displaying >1,000-fold selectivity against CHK2 and CDK1. It potently inhibits cellular CHK1 activity (IC50 30-220nM) and enhances gemcitabine and SN38 cytotoxicity in multiple human tumor cell lines and human tumor xenograft models. It causes inhibition of tumor growth in an Eμ-Myc mouse model of human B-cell lymphocytic leukemia. Synonyms: CCT-245737; CCT 245737; CCT245737; 5-[(4-{[(2R)-morpholin-2-ylmethyl]amino}-5-(trifluoromethyl)pyridin-2-yl)amino]pyrazine-2-carbonitrile. CAS No. 1489389-18-5. Molecular formula: C16H16F3N7O. Mole weight: 379.347.
CCT-251236
CCT-251236 is an orally active Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen, which exhibited efficacy in a human ovarian carcinoma xenograft model. Uses: The potential treatment of ovarian carcinoma. Synonyms: CCT251236; CCT 251236; N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamido)-2-methylphenyl)-2-(2-(pyrrolidin-1-yl)ethoxy)quinoline-6-carboxamide; N-[5-(2,3-dihydro-1,4-benzodioxine-6-amido)-2-methylphenyl]-2-[2-(pyrrolidin-1-yl)ethoxy]quinoline-6-carboxamide; 6-Quinolinecarboxamide, N-[5-[[(2,3-dihydro-1,4-benzodioxin-6-yl)carbonyl]amino]-2-methylphenyl]-2-[2-(1-pyrrolidinyl)ethoxy]-. Grades: ≥95%. CAS No. 1693731-40-6. Molecular formula: C32H32N4O5. Mole weight: 552.62.
CDDO Imidazolide
CDDO Imidozolide is a synthetic triterpenoid as a Nrf2 signaling activator with highly active in suppressing cellular proliferation of human leukemia and breast cancer cell. Uses: Nrf2 signaling activator. Synonyms: 1-(2-Cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl)-1H-imidazole; (4aR,6aR,6aS,6bR,8aS,12aS,14bS)-8a-(imidazole-1-carbonyl)-4,4,6a,6b,11,11,14b-heptamethyl-3,13-dioxo-4a,5,6,6a,7,8,9,10,12,12a-decahydropicene-2-carbonitrile. Grades: ≥98 %. CAS No. 443104-02-7. Molecular formula: C34H43N3O3. Mole weight: 541.72.
Cefotetan disodium
Cefotetan is a second-generation cephalosporin. It can bind to penicillin-binding proteins and disrupts the cell wall synthesis. Cefotetan is active against some strains of β-lactamase producing bacteria. Cefotetan shows anti-microbial activity against Gram-positive and Gram-negative bacteria and it is more efficacious against Gram-negative and anaerobic bacteria. Uses: Antibacterial. Synonyms: ICI156834; ICI 156834; ICI-156834; YM 09330; YM09330; YM-09330; Yamatetan; Cefotan; Apatef; 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, sodium salt (1:2), (6R,7S)-; 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, disodium salt, (6R,7S)-; 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, disodium salt, [6R-(6α,7α)]-; Cefotetan sodium; Ceftenon; Cepan Darvilen. Grades: 98%. CAS No. 74356-00-6. Molecular formula: C17H15N7Na2O8S4. Mole weight: 619.59.
Cefpodoxime proxetil
It is produced by the strain of Semisynthetic third generation cephalosporin. Cefpodoxime is active against most Gram-positive and Gram-negative organisms. It can be used to treat acute otitis media, pharyngitis, sinusitis, and gonorrhea. Uses: Antibacterial agent. Synonyms: Antibiotic CS 807; Banan; CS 807; Cefodox; Cefoprox; Cephpodoxime Proxetil; Cepodem; Orelox; Otreon; RU 51807; U 76252; Vantin; 1-{[(propan-2-yloxy)carbonyl]oxy}ethyl (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate. Grades: 98%. CAS No. 87239-81-4. Molecular formula: C21H27N5O9S2. Mole weight: 557.60.
CGI1746
CGI1746 is a small-molecule Btk inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation. CGI1746 has exquisite selectivity for Btk and inhibits both auto- and transphosphorylation steps necessary for enzyme activation. Synonyms: CGI1746; CGI-1746; CGI 1746. 4-(tert-Butyl)-N-(2-methyl-3-(4-methyl-6-((4-(morpholine-4-carbonyl)phenyl)amino)-5-oxo-4,5-dihydropyrazin-2-yl)phenyl)benzamide. Grades: 98%. CAS No. 910232-84-7. Molecular formula: C34H37N5O4. Mole weight: 579.69.
CGI1746
CGI1746 is a small-molecule Btk inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation. CGI1746 has exquisite selectivity for Btk and inhibits both auto- and transphosphorylation steps necessary for enzyme activation. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CGI1746; CGI-1746; CGI 1746. Product Category: Inhibitors. Appearance: White to off-white solid powder. CAS No. 910232-84-7. Molecular formula: C34H37N5O4. Mole weight: 579.69. Purity: >98%. IUPACName: 4-(tert-butyl)-N-(2-methyl-3-(4-methyl-6-((4-(morpholine-4-carbonyl)phenyl)amino)-5-oxo-4,5-dihydropyrazin-2-yl)phenyl)benzamide. Canonical SMILES: O=C(NC1=CC=CC(C(N=C2NC3=CC=C(C(N4CCOCC4)=O)C=C3)=CN(C)C2=O)=C1C)C5=CC=C(C(C)(C)C)C=C5. Product ID: ACM910232847. Alfa Chemistry ISO 9001:2015 Certified.
Cgp-17520
Cgp-17520 is a new bio-active cephalosporin anti-biotic chemical comound synthesized by Ciba Geigy Ltd. Synonyms: Cgp 17520; Cgp-17520; Cgp17520. 7-(2-(4-(((2-Amino-2-carboxyethoxy)carbonyl)amino)phenyl)-2-hydroxyacetamido)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt. Grades: >98 %. CAS No. 101706-66-5. Molecular formula: C22H24N8NaO9S2. Mole weight: 631.59.
Chlorfenapyr
Chlorfenapyr is a halogenated pyrrole based pro-insecticide. Chlorfenapyr functions by metabolizing into an active insecticide after entering the host. Chlorfenapyr is used primarily as a means of pest control on cotton. Group: Biochemicals. Alternative Names: 4-Bromo-2- (p-chlorophenyl) -1- (ethoxymethyl) -5- (trifluoromethyl) pyrrole-3-carbonitrile; AC 303-630; AC 303630; CL 303630; Chlorfenapyr; Citrex (acaricide); Kotetsu; Mystox MP; Phantom; Pirate 3F; Pylon; Rampage; Secure 360SC Insecticide-Miticide; Stealth. Grades: Highly Purified. CAS No. 122453-73-0. Pack Sizes: 1g. US Biological Life Sciences.
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