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| Product | Description | |
|---|---|---|
| Adjuvant Peptide | Adjuvant Peptide is an immunomodulatory factor that can be used as a vaccine adjuvant to enhance immune response. It inhibits HIV replication in CD4+H9 lymphocytes. Uses: Adjuvants, immunologic. Synonyms: D-α-Glutamine, N-(N-acetylmuramoyl)-L-alanyl-; D-α-Glutamine, N2-[N-(N-acetylmuramoyl)-L-alanyl]-; N-(N-Acetylmuramoyl)-L-alanyl-D-α-glutamine; Acetylmuramoyl-L-alanyl-D-isoglutamine; MDP; MDP-D; Muramoyl dipeptide; N-(Acetylmuramoyl)-L-alanyl-D-isoglutamine; N-(Acetylmuramoyl)alanyl-D-isoglutamine; N-Acetylmuramoyl dipeptide; N-Acetylmuramoyl-L-alanine-D-isoGln; N-Acetylmuramoylalanyl-D-isoglutamine; (4R,5R,7R,10S,13R)-13-carbamoyl-4-formyl-7,10-dimethyl-2,8,11-trioxo-5-((1R,2R)-1,2,3-trihydroxypropyl)-6-oxa-3,9,12-triazahexadecan-16-oic acid; N-Ac-Mur-Ala-D-Glu-NH2; N-Acetylmuramyl-L-Ala-D-Glu-NH2; Muramyl dipeptide. Grades: ≥95%. CAS No. 53678-77-6. Molecular formula: C19H32N4O11. Mole weight: 492.48. |  |
| Alum Adjuvant | Alum Adjuvant is insoluble white colloidal suspension of aluminum hydroxide used to potentiate immune response. Antigen adsorbs on the aluminum hydroxide precipitate and when injected form a depot of insoluble antigen at injection site which attracts immune cells and enhance immune response. It is used to raise polyclonal and monoclonal antibodies and is less toxic when compared to Freunds complete adjuvant. Synonyms: Mixture of Aluminum Hydroxide and Magnesium Hydroxide. | |
| Aluminum Hydroxide Adjuvant | Aluminum hydroxide adjuvant is a white hydrogel that sediments slowly and forms a clear supernatant. Synonyms: Alhydrogel; aluminii hydroxidum hydricum ad adsorptionem; aluminium hydroxide adjuvant; aluminium oxyhydroxide; poorly crystalline boehmite; pseudoboehmite; Rehydragel. CAS No. 21645-51-2. Product ID: PE0377. Molecular formula: AlO(OH). Mole weight: 59.99. Category: Adsorbents. Product Keywords: Pharmaceutical Excipients; Excipients for Solid Dosage Form; Filler Excipients; Absorbent; Aluminum Hydroxide Adjuvant; PE0377; 5QB0T2IUN0; 21645-51-2; 21645-51-2. UNII: 5QB0T2IUN0. Chemical Name: Aluminum oxyhydroxide. Grade: Pharmceutical Excipients. Stability and Storage Conditions: Aluminum hydroxide adjuvant is stable when stored at 4-30°C in well-sealed inert containers. It must not be allowed to freeze as the hydrated colloid structure will be irreversibly damaged. Applications: Aluminum hydroxide adjuvant is used in parenteral human and veterinary vaccines. Safety: Aluminum hydroxide adjuvant is intended for use in parenteral vaccines and is generally regarded as nontoxic. |  |
| Aluminum Phosphate Adjuvant | Aluminum phosphate adjuvant is a white hydrogel that sediments slowly and forms a clear supernatant. Synonyms: Adju-Phos; aluminum hydroxyphosphate; aluminium hydroxyphosphate; Rehydraphos. Product ID: PE0379. Molecular formula: Al(OH)x(PO4)y. Category: Adsorbents. Product Keywords: Pharmaceutical Excipients; Excipients for Solid Dosage Form; Filler Excipients; Absorbent; Aluminum Phosphate Adjuvant; PE0379. Chemical Name: Aluminum phosphate. Grade: Pharmceutical Excipients. Stability and Storage Conditions: Aluminum phosphate adjuvant is stable fwhen stored at 4-30°C in well-sealed inert containers. It must not be allowed to freeze as the hydrated colloid structure will be irreversibly damaged. Applications: Aluminum phosphate adjuvant is used in parenteral human and veterinary vaccines. Safety: Aluminum phosphate adjuvant is intended for use in parenteral vaccines and is generally regarded as safe. It may cause mild irritation, dryness, and dermatitis on skin contact. It may also cause redness, conjunctivitis, and short-term mild irritation on eye contact. Ingestion of large amounts of aluminum phosphate adjuvant may cause respiratory irritation with nausea, vomiting, and constipation. Inhalation is unlikely, although the dried product may cause respiratory irritation and cough. Type I hypersensitivity reactions following parenteral administration have also been reported. | |
| AS 15 (immune adjuvant) | AS 15 (immune adjuvant) is a liposomal immune adjuvant contg. CpG 7909, monophosphoryl lipid A, and Quillaja saponin 21. Synonyms: AS 15. CAS No. 1351362-53-2. | |
| FREUND'S COMPLETE ADJUVANT | FREUND'S COMPLETE ADJUVANT. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ADJUVANT, COMPLETE(FREUND);ADJUVANT, COMPLETE, FREUND, H37 RV;IMJECT FREUND'S COMPLETE ADJUVANT;FCA;FREUNDS COMPLETE ADJUVANT;FREUND'S COMPLETE ADJUVANT;FREUND'S COMPLETE ADJUVANT, MODIFIED;FREUND'S COMPLETE ADJUVANT, MODIFIED, MYCOBACTERIUM BUTYRICUM. Product Category: Heterocyclic Organic Compound. CAS No. 9007-81-2. Product ID: ACM9007812. Alfa Chemistry ISO 9001:2015 Certified. |  |
| MPLA (Synthetic) Sterile Solution (Monophosphoryl Lipid A, Phosphorylated Hexaacyl Disaccharide, Glycopyranoside Lipid A, Glucopyranosyl Lipid Adjuvant, GLA) | Toll-like receptor 4 (TLR4) activator. Activates TLR4 but does not activate TLR2 even at high concentrations. Defined structure of MPLA. Synthetic lipid A is structurally very similar to natural MPLA but does not exist in nature. Group: Biochemicals. Grades: Cell Culture Grade. CAS No. 1246298-63-4. Pack Sizes: 100ug. US Biological Life Sciences. |  Worldwide |
| 16:0 EPC chloride | 16:0 EPC chloride, a P-O-ethyl derivative, is a saturated cationic lipid. 16:0 EPC chloride can serve as a DNA and RNA transfecting agent. 16:0 EPC chloride can be used as a co-adjuvant for preparing vaccines and promote drug delivery [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 328250-18-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144016. |  |
| 1-Amino-1-deoxy-D-galactitol hydrochloride | 1-Amino-1-deoxy-D-galactitol hydrochloride is a vital compound in the biomedical industry. Widely recognized for its potential in treating Type 2 diabetes and diabetic complications, this product acts as a promising adjuvant therapy due to its ability to control blood glucose levels effectively. Synonyms: (2R,3S,4R,5S)-6-aminohexane-1,2,3,4,5-pentol; 1-Amino-1-deoxy-D-galactitol; rel-(2R,3S,4R,5S)-6-aminohexane-1,2,3,4,5-pentaol;1-amino-1-deoxygalactose; 1-amino-1-deoxygalactitol;(2R,3S,4R,5S)-6-Aminohexane-1,2,3,4,5-pentaol. CAS No. 488-42-6. Molecular formula: C6H15NO5.HCl. Mole weight: 217.65. | |
| 2',3'-cGAMP sodium salt | 2',3'-cGAMP sodium is an endogenous cGAMP in mammalian cells. 2',3'-cGAMP sodium binds to STING with a high affinity and is a potent inducer of interferon-&beta. 2',3'-cGAMP is an effective adjuvant that boosts the production of antigen-specific antibodies and T cell responses in mice. Synonyms: Cyclic [G(2',5')pA(3',5')p] sodium; cyclic GMP-AMP sodium; 2',3'-cyclic GMP-AMP sodium; 2',3'-Cyclic guanosine monophosphate-adenosine monophosphate sodium salt. Grades: 95%. CAS No. 2734858-36-5. Molecular formula: C20H22N10Na2O13P2. Mole weight: 718.38. | |
| 2-Hydroxy Imiquimod | 1-(4-Amino-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol, has been shown to activate a toll-like receptor 7/8 Independent Cytokine, which can be used in the design of immunomodulating agents for use as vaccine adjuvants and anticancer treatments. Group: Biochemicals. Grades: Highly Purified. CAS No. 112668-45-8. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C14H16N4O. US Biological Life Sciences. | Worldwide |
| (2S)-2-(2-Chlorophenyl)-2-(1-methoxy-1-methylethoxy)Ethyl Ester 1H-Imidazole-1-carboxylic Acid | (2S)-2-(2-Chlorophenyl)-2-(1-methoxy-1-methylethoxy)Ethyl Ester 1H-Imidazole-1-carboxylic Acid is an intermediate in the synthesis of (S)-Carisbamate (C183510). Carisbamate is being developed for adjuvant treatment of partial onset epilepsy. Carisbamate produces anticonvulsant effects in primary generalized, complex partial and absence-type seizure models, and exhibits neuroprotective and antiepileptogenic properties in rodent epilepsy models. Group: Biochemicals. Grades: Highly Purified. CAS No. 1146981-97-6. Pack Sizes: 10mg, 25mg. Molecular Formula: C16H19ClN2O4, Molecular Weight: 338.79. US Biological Life Sciences. | Worldwide |
| (2S,3R,4E)-2-Amino-4-hepten-1,3-diol | An intermediate for immunological adjuvant compounds. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| (2S,3R,4E)-2-Amino-4-hepten-1,3-diol Ethyl Ether | An intermediate for immunological adjuvant compounds. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| (2S,3R,4E)-2-Butyrylamino-4-hepten-1,3-diol | An intermediate for immunological adjuvant compounds. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| (2S,3R,4E)-2-Butyrylamino-4-tetradecene-1,3-diol | An intermediate for immunological adjuvant compounds. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 3-(7-Ethyl-3-(2-hydroxyethyl)-1H-indol-2-yl)pent-2-enoic Acid | 3-(7-Ethyl-3-(2-hydroxyethyl)-1H-indol-2-yl)pent-2-enoic Acid is a a double bond isomer of Etodolac Impurity L which is an impurity of Etodolac (racemic, E933100), a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2 (COX-2). Etodolac displays anti-inflammatory effects in both adjuvant arthritic and normal rats. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C17H21NO3, Molecular Weight: 287.35. US Biological Life Sciences. | Worldwide |
| 3'-CPR II CPG | 3'-CPR II CPG, a vital tool in molecular biology, is renowned for unraveling the elusive role of Toll-like receptor 9 (TLR9) in shaping the immune system. In the domain of immunotherapy, the adjuvant supplements DNA vaccines and jumpstarts immune responses to eradicate cancer and infections. Dive into the intriguing world of 3'-CPR II CPG as its therapeutic potential has undergone rigorous scrutiny in pre-clinical and clinical trials. Synonyms: 3-(4,4'-Dimethoxytrityloxy)-2,2-(dicarboxymethylamido)propyl-1-O-succinoyl-long chain alkylamino-CPG. Mole weight: 79.98. | |
| 3'-QD-1 CPG 1000 | 3'-QD-1 CPG 1000, a phosphorothioate oligodeoxynucleotide, has consistently garnered attention in the field of biomedical research. Its immunostimulatory effects on dendritic cells have been ardently examined, and it has been postulated as a potent adjuvant in cancer immunotherapy. The sheer magnitude of research that has been conducted on this ochreous substance can leave one quite breathless. | |
| 3'-QD-3 CPG 1000 | 3'-QD-3 CPG 1000 is a synthetic oligonucleotide used as an immune modulator in the treatment of cancer and infectious diseases. It enhances the activation of immune cells to increase anti-tumor and anti-viral responses. It is also used as an adjuvant therapy with vaccine treatments for various types of cancer. | |
| 4A-MPLA | 4A-MPLA, the synthetic antigen-adjuvant, is employed in vaccines that bolster immune responses to infectious agents and cancers. The toll-like receptor 4 (TLR4) is vigorously activated by this powerful agonist, which, when given with other adjuvants, augments vaccine effectiveness during vaccination programs intended to combat bacterial and viral infections, including tuberculosis, influenza, and meningitis. Synonyms: Monophosphoryl Tetra-acyl Lipid A. Grades: 98%. CAS No. 2260669-09-6. Molecular formula: C68H132N3O19P. Mole weight: 1326.76. | |
| 7DW8-5 | 7DW8-5, a novel glycolipid, an analog of α-galactosylceramide (α-GalCer), is an immunostimulate iNKT agonist and a vaccine adjuvant that can harness and amplify the immunotherapeutic potential of NKT cells to treat certain microbial infections such as malaria and HIV. Studies have shown that the adjuvant effect of 7DW8-5 wasmediated by CD1dmolecules. Synonyms: [(2S,3S,4R)-1-O-(α-D-galactopyranosyl)-N-(11-(4-fluorophenyl)undecanoyl)-2-amino-1,3,4-octadecanetriol)]; N-[(2S,3S,4R)-3,4-dihydroxy-1-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoctadecan-2-yl]-11-(4-fluorophenyl)undecanamide; 11-(4-Fluorophenyl)-N-[(2s,3s,4r)-1-(Alpha-D-Galactopyranosyloxy)-3,4-Dihydroxyoctadecan-2-Yl]undecanamide; CHEBI:86489; 7DW8-5; 7DW. CAS No. 1056025-00-3. Molecular formula: C41H72FNO9. Mole weight: 742. | |
| 8-Hydroxyguanosine | It is a representative metabolite derived by the oxidation of Guanosine (G) and is regarded as a marker of oxidative stress in the cells. It is also an RNA adduct. Uses: Adjuvants, immunologic. Synonyms: 2-Amino-9-β-D-ribofuranosyl-purine-6,8(1H,9H)-dione; 8-OHG; 8-Oxo-7,8-dihydroguanosine; 8-Oxoguanosine; NSC 90393; 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-hydroxy-1H-purin-6(9H)-one; 7,8-dihydro-8-oxoguanosine. Grades: ≥97%. CAS No. 3868-31-3. Molecular formula: C10H13N5O6. Mole weight: 299.24. | |
| 8-Thioguanosine | 8-Thioguanosine is a significant compound exhibiting remarkable capabilities in studying viral infections and cancer. By proficiently curtailing viral RNA and DNA replication, it effectively subdues the menace of virulence, while concurrently impeding the enhancement of nucleic acids within cancerous cells. Uses: Adjuvants, immunologic. Synonyms: 8-Mercaptoguanosine; 8-SH-Guo; 2-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-mercapto-1H-purin-6(9H)-one; 7,8-Dihydro-8-thioxoguanosine; 8-Mercapto-7,8-dihydroguanosin; 8-Tio-Guanosine. Grades: ≥97% by HPLC. CAS No. 26001-38-7. Molecular formula: C10H13N5O5S. Mole weight: 315.31. | |
| 9-Aminoacridine | 9-Aminoacridine, a fluorescent probe, acts as an indicator of pH for quantitative determination of transmembrane pH gradients (inside acidic). 9-Aminoacridine is an antimicrobial. 9-Aminoacridine exerts its antimicrobial activity by interacting with specific bacterial DNA and disrupting the proton motive force in K. pneumoniae. 9-Aminoacridine is a HIV-1 inhibitor and inhibits HIV LTR transcription highly dependent on the presence and location of the amino moiety. 9-Aminoacridine inhibits virus replication in HIV-1 infected cell lines. 9-Aminoacridine is used as a Rifampin (RIF; HY-B0272) adjuvant for the multidrug-resistant K. pneumoniae infections [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Aminacrine. CAS No. 90-45-9. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg; 1 g. Product ID: HY-B1422. | |
| 9-cis Retinol Acetate | A retinal derivative for treatment of visual disorders. Uses: Adjuvants, immunologic. Synonyms: 9-cis-Retinyl Acetate; 9-cis-Vitamin A Acetate; 9-cis-Vitamin A1 Acetate. Grades: > 95%. CAS No. 29584-22-3. Molecular formula: C22H32O2. Mole weight: 328.5. | |
| A22 hydrochloride | A22 is an inhibitor of MreB, an actin-like bacterial protein, and has been shown to act as an antiobiotic adjuvant. A22 inhibition of MreB disrupts the bacterial actin cytoskeleton, which can cause an increase in cell permeability and altered transport. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MreB Perturbing Compound A22; A22 hydrochloride. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 22816-60-0. Molecular formula: C8H9Cl3N2S. Mole weight: 271.58. Purity: >98%. IUPACName: S-(3,4-Dichlorobenzyl)isothiourea hydrochloride. Canonical SMILES: N=C(N)SCC1=CC=C(Cl)C(Cl)=C1.[H]Cl. Product ID: ACM22816600-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| A740003 (N-(1-{[(cyanoimino)(5-quinolinylamino) methyl] amino}-2, 2-dimethylpropyl) -2- (3, 4-dimethoxyphenyl) acetamide, A 740003, P2X7 Purinegic Receptor, A740003, A740003) | A highly potent, selective, competitive antagonist of P2X7 purinegic receptor (IC50 = 18nM and 40nM, respectively as measured by Bz-ATP-stimulated Ca2+ flux). Does not affect other P2 receptors even at 10uM concentrations. Blocks agonist-evoked IL-1b release (IC50 = 156nM) and pore formation (IC50 = 92nM) in differentiated human THP-1 cells. Also shown to reduce carrageenan and Freund's adjuvant -induced thermal hyperalgesia (ED50 = 38-54mg/kg, i.p) and neuropathic pain induced by chronic constriction injury (CIC) of the sciatic nerve. Group: Biochemicals. Grades: Highly Purified. CAS No. 861393-28-4. Pack Sizes: 5mg. Molecular Formula: C??H??N?O?, Primary Target: P2X7. US Biological Life Sciences. | Worldwide |
| A 841720 | A 841720 is a potent non-competitive mGlu1 receptor antagonist (IC50 = 10 nM) exhibiting 34-fold selectivity over mGluR5 and inactive to other mGluR receptors, neurotransmitter receptors, ion channels, and transporters. It inhibits complete Freund's adjuvant-induced inflammatory pain (ED50 = 23 μmol/kg) and decreases mechanical allodynia (ED50 = 28 μmol/kg) in mouse models. Synonyms: A-841720; A 841720; A841720; 3-(azepan-1-yl)-9-(dimethylamino)pyrido[1,2]thieno[3,4-d]pyrimidin-4-one. Grades: 99%. CAS No. 869802-58-4. Molecular formula: C17H21N5OS. Mole weight: 343.45. | |
| Acedoben | Acedoben is a biochemical agent. Acedoben and iron ions can construct a fast self-assembled coordination complex. The Fe-Ace coordination complex can not only serve as a carrier of tumor antigens, but also enhance antigen-specific anti-tumor immunity due to its inherent adjuvant properties [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 556-08-1. Pack Sizes: 10 mM * 1 mL; 10 g. Product ID: HY-B1250. | |
| Acedoben sodium | Acedoben sodium is the sodium salt form of Acedoben. Acedoben and iron ions can construct a rapidly self-assembled coordination complex, and the Fe-Ace coordination complex can not only serve as a carrier of tumor antigens, but also enhance antigen-specific anti-tumor immunity due to its inherent adjuvant properties [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 29305-16-6. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1250A. | |
| Agatolimod sodium | Agatolimod sodium selectively targets Toll-like receptor 9 (TLR9). It has potential antineoplastic and immunostimulatory activity and is used as an anticancer adjuvant and immunostimulant. Synonyms: DNA, d(P-thio)(T-C-G-T-C-G-T-T-T-T-G-T-C-G-T-T-T-T-G-T-C-G-T-T), tricosasodium salt; ODN 7909; AS 07A; CpG 2006 sodium salt; CpG ODN 7909; CpG 7909; PF-3512676; ProMune; ProMune CpG 7909. Grades: 98%. CAS No. 541547-35-7. Molecular formula: C238H291N75Na23O127P23S23. Mole weight: 8212.89. | |
| AJS75 | AJS75, the most adjuvant-active fraction of AJSt, could improve antigen-specific both cellular and humoral immune responses and simultaneously elicit a Th1/Th2 response by inducing cytokine and chemokine at the site of injection. | |
| α-Carotene | α-Carotene, a precursor of vitamin A, is used as an anti-metastatic agent or as an adjuvant for anti-cancer agents. α-Carotene is isolated from yellow-orange and dark-green vegetables [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 7488-99-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-113462. | |
| Aluminium phosphate | Aluminium phosphate occurs in nature as the mineral, berlinite. Also, it occurs in nature in minerals, amblygonite, [NaAl(PO4)(OH)]; augelite, [Al2(PO4)(OH)3]; lazulite, [(Mg,Fe)Al2(PO4)2(OH)2]; variscite [(Al,Fe3+)(PO4) 2H2O]; and wavellite, [Al3(OH)3 (PO4)2 5H2O]. It is used as flux for ceramics; as cement in combination with calcium sulfate and sodium silicate; and in the manufacture of special glasses. It is also used in dried gel and therapeutically as an antacid. Product ID: PE-0677. Molecular formula: AlPO4. Mole weight: 121.9529. Category: Antacid; vaccine adjuvant. Product Keywords: Vaccine Adjuvants; PE-0677; Aluminium phosphate. Chemical Name: Aluminium phosphate. Grade: Pharmaceutical grade. Administration route: Accepted for use in human and veterinary vaccines. Dosage Form: Accepted for use in human and veterinary vaccines. Stability and Storage Conditions: Aluminum phosphate adjuvant is stable for at least 2 years when stored at 4-308°C in well-sealed inert containers. It must not be allowed to freeze as the hydrated colloid structure will be irreversibly damaged. Source and Preparation: Aluminum phosphate adjuvant is formed by the reaction of a solution of aluminum chloride and phosphoric acid with alkali hydroxide. Applications: Aluminum Phosphate is an odorless, white crystalline solid which is often used in liquid or gel form. It is used in ceramics, dental cements, cosmetics, paints, paper an | |
| Aluminum Hydroxide | Aluminum Hydroxide is an orally active main form of aluminum used as adjuvant. Aluminum hydroxide-based adjuvant researches include the repository effect, pro-phagocytic effect, and activation of the pro-inflammatory NLRP3 pathway. Aluminum Hydroxide also acts as adjuvant to compensate low inherent immunogenicity of subunit vaccines [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 21645-51-2. Pack Sizes: 500 mg; 1 g. Product ID: HY-B1521. | |
| Amino-PEG7-alcohol | Amino-PEG7-alcohol (CAS# 1425973-14-3) is a reagent used in pharmaceutical preparations such as the preparation of a water-soluble cancer vaccine adjuvant. Synonyms: 2- [2- [2- [2- [2- [2- (2-aminoethoxy) ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethanol; 2- [2- [2- [2- [2- [2- (2-aminoethoxy) ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethanol. Grades: >97%. CAS No. 1425973-14-3. Molecular formula: C14H31NO7. Mole weight: 325.40. | |
| Amorphous aluminum hydroxyphosphate sulfate | Amorphous aluminum hydroxyphosphate sulfate (AAHS) is an aluminum-containing adjuvant produced by Merck & Company (Rahway, NJ, USA), and is used in several commercial vaccines, including Recombivax, Gardasil, and Vaxelis. Synonyms: AAHS; aluminum hydroxyphosphate sulfate. CAS No. 150828-31-2. Molecular formula: AlHO9PS-3. Mole weight: 235.03. | |
| AS03 | AS03 is an Adjuvant System composed of α-tocopherol, squalene and polysorbate 80 in an oil-in-water emulsion. AS03 has been shown to trigger transient NF-κB-dependent innate immune responses. | |
| Atropine sulfate hydrate (2:1:1) | Atropine is a medication used to treat certain types of nerve agent and pesticide poisonings, some types of slow heart rate, and to decrease saliva production during surgery. Uses: Adjuvants, anesthesia. Synonyms: Atropine sulfate monohydrate; Atropini sulfas; Isopto Atropine; Atropinum sulphuricum; Atropine sulfate. Grades: >98%. CAS No. 5908-99-6. Molecular formula: 2C17H23NO3.H2O4S.H2O. Mole weight: 694.837. | |
| Atropine sulfate hydrate (2:1:2) | . Uses: Adjuvants, anesthesia. Synonyms: endo-8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 3-hydroxy-2-phenylpropanoate sulfate dihydrate(2:1:2). CAS No. 73791-47-6. Molecular formula: 2C17H23NO3.H2O4S.2H2O. Mole weight: 712.852. | |
| Autotaxin Inhibitor III, PF-8380 (Atx Inhibitor III, PF-8380, 6-(3-(Piperazin-1-yl)propanoyl)-benzo[d]oxazol-2(3H)-one) | An orally bioavailable piperazinyl benzoxazolone compound that acts as a substrate competitive and tight-binding inhibitor of autotaxin activity {IC50=2.8 and 1.7nM for recombinant human enzyme-b isoform employing FS-3 and LPC (lysophosphatidyl choline) as substrates, respectively; 1.16 and 1.15nM for rat/murine enzyme-FS-3 and fetal fibroblast cell-LPC; 101nM for human whole blood}. Displays desirable pharmacokinetics properties and efficiently blocks inflammation-induced LPA (lysophosphatidic acid) production both in plasma and at the site of inflammation by 95% in rat adjuvant-induced arthritis model (30mg/kg, p.o.).CAS No:1144035-53-9. Group: Biochemicals. Grades: Highly Purified. CAS No. 1144035-53-9. Pack Sizes: 10mg. Molecular Formula: C??H??Cl?N?O?. US Biological Life Sciences. | Worldwide |
| Avridine | A potent synthetic non-immunogenic adjuvant that can induce arthritis in most rat strains; immunomodulator and interferon-inducing. Group: Biochemicals. Alternative Names: 2, 2'- [ [3- (Dioctadecylamino) propyl] imino] bisethanol; CP 20961; CP-20961; N,N-Dioctadecyl-N',N'-bis(2-hydroxyethyl)-1,3-diaminopropane; N, N-Dioctadecyl-N', N'-bis (2-hydroxyethyl) propanediamine. Grades: Highly Purified. CAS No. 35607-20-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Avridine | Avridine is a potent synthetic non-immunogenic adjuvant that used to induce arthritis in Lewis (LEW) and DA rats. Uses: A potent synthetic non-immunogenic adjuvant that can induce arthritis in most rat strains; immunomodulator and interferon-inducing. Synonyms: CP 20961; CP20961; CP-20961;N,N-Dioctadecyl-N',N'-bis(2-hydroxyethyl)-1,3-diaminopropane. Grades: ≥98%. CAS No. 35607-20-6. Molecular formula: C43H90N2O2. Mole weight: 667.19. | |
| b-D-Glucan - from Yeast (Saccharomyces Cerevisiae) | b-D-Glucan - from Yeast (Saccharomyces Cerevisiae): b-D-Glucan, derived from Saccharomyces cerevisiae yeast, is a natural compound utilized in the biomedical industry. Widely recognized for its immunomodulatory properties, b-D-Glucan is extensively employed as an adjuvant in vaccines and therapeutics for enhancing immune responses. Uses: Adjuvants, immunologic. Synonyms: 1,3-b-D-Glucan; b-1,3-D-Glucan. CAS No. 9012-72-0. Molecular formula: (C6H10O5)n. Mole weight: 472.4. | |
| Benfotiamine | Benfotiamine is an amphiphilic S-acyl thiamine derivative used as a lipid soluble alternative source of bioavailable thiamine. Benfotiamine is being investigated in a variety of therapeutic applications. Uses: Adjuvants, immunologic. Synonyms: Benzenecarbothioic acid, S-[2-[[(4-amino-2-methyl-5-pyrimidinyl)methyl]formylamino]-1-[2-(phosphonooxy)ethyl]-1-propen-1-yl] ester; Benzoylthiamine monophosphate; Berdi; Betivina; Bietamine; Biotamin; Milgamma; Nitanevril; S-Benzoylthiamine O-monophosphate; Tabiomyl; Vitanevril; BTMP; Benzenecarbothioic acid, S-[2-[[(4-amino-2-methyl-5-pyrimidinyl)methyl]formylamino]-1-[2-(phosphonooxy)ethyl]-1-propenyl] ester; Benzoic acid, thio-, S-ester with N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-(4-hydroxy-2-mercapto-1-methyl-1-butenyl)formamide dihydrogen phosphate (ester); Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-(4-hydroxy-2-mercapto-1-methyl-1-butenyl)-, S-benzoate O-(dihydrogen phosphate); 8088CB; Benfothiamine; Benzoylthiamine O-monophosphate; N-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-(4-hydroxy-2-mercapto-1-methyl-1-butenyl)formamide S-benzoate O-phosphate; Neurostop; S-Benzoylthiamine monophosphate. Grades: >98%. CAS No. 22457-89-2. Molecular formula: C19H23N4O6PS. Mole weight: 466.45. | |
| Bifendate | Bifendate is a synthetic intermediate of schisandrin C, a dibenzocyclooctadiene derivative derived from lignans used in traditional medicine and also a anti-HBV drug used in the treatment of chronic hepatitis B. It has been used in some countries as a hepatoprotectant adjuvant in the treatment of liver diseases, such as chronic viral hepatitis or drug-induced hepatic damage. Uses: Cytochrome p-450 enzyme inhibitors. Synonyms: 7,7'-Dimethoxy-[4,4'-Bi-1,3-benzodioxole]-5,5'-dicarboxylic Acid 5,5'-Dimethyl Ester; DDB; Dimethyl 4,4'-Dimethoxy-5,6,5',6'-di(methylenedioxy)biphenyl-2,2'-dicarboxylate; Dimethyl dicarboxylate Biphenyl; α-DDB. Grades: 97.0%~103.0%. CAS No. 73536-69-3. Molecular formula: C20H18O10. Mole weight: 418.36. | |
| Bindarit | Bindarit shows anti-inflammatory activity due to a selective inhibition of a subfamily of inflammatory chemokines. Bindarit is a also protein antidenaturant agent. Bindarit modulates the NFkB pathway and has been shown to reduce secondary phase of adjuvant arthritis in rats. Group: Biochemicals. Alternative Names: 2-Methyl-2-[[1-(phenylmethyl)-1H-indazol-3-yl]methoxy]propanoic Acid; 2-[(1-Benzyl-1H-indazol-3-yl)methoxy]-2-methylpropanoic Acid; 2-[(1-Benzyl-1H-indazol-3-yl)methoxy]-2-methylpropionic Acid; AF 2838. Grades: Highly Purified. CAS No. 130641-38-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| BMS-566419 | Potent inosine monophosphate dehydrogenase (IMPDH) inhibitor (IC50 = 17 nM). Inhibits proliferation of human T-lymphoblasts and PBMCs in vitro. Reduces paw swelling in a rat adjuvant arthritis model. Synonyms: BMS 566419; BMS566419; N-(1-(6-(4-Ethyl-1-piperazinyl)-3-pyridinyl)-1-methylethyl)-2-fluoro-9,10-dihydro-9-oxo-3-acridinecarboxamide. Grades: >98%. CAS No. 566161-24-8. Molecular formula: C28H30FN5O2. Mole weight: 487.57. | |
| Bryostatin 1 | Bryostatin 1, a structurally unique macrolactone marine natural product, is a protein kinase C (PKC) activator that binds with high affinity (Ki = 1.35 nM). Bryostatin 1 fails to mimic many effects caused by PMA and actually blocks some PMA-induced response in a variety of cells and tissues. Animal tests have shown bryostatin 1 may alleviate brain damage after a stroke. Uses: Adjuvants, immunologic. Synonyms: Bryostatin-1; Bryostatin1; NSC-339555; NSC 339555; NSC339555; AC1L8WCW. Grades: ≥99%. CAS No. 83314-01-6. Molecular formula: C47H68O17. Mole weight: 905.04. | |
| Bupirimate | Bupirimate possesses antifungal activity. Bupirimate is compatible with most of fungicides, insecticides and adjuvants, with very limited exceptions on some crops [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 41483-43-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133216. | |
| C6 Ceramide | C6 Ceramide (C6-Cer) is a short-chain, cell-permeable ceramide pathway activator with anticancer activity. C6 Ceramide-mediated miR-29b expression participates in the progression of multiple myeloma through suppressing the proliferation, migration and angiogenesis of endothelial cells by targeting Akt signal pathway. C6 Ceramide exhibits multiple anti-cancer properties including cell cycle arrest, Apoptosis , inhibition of tumor growth and enhances the effects of chemotherapy in drug-resistant cancer cells. C6-ceramide can be used as an adjuvant for chemotherapeutic agents, to enhance anti-tumor effects [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: C6-Cer; N-Hexanoylsphingosine. CAS No. 124753-97-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19542. | |
| Calcium Levofolinate | Calcium Levofolinate is a calcium salt of folinic acid that is an adjuvant used in cancer chemotherapy. Synonyms: Saponins. Grades: >98%. CAS No. 80433-71-2. Molecular formula: C20H21CaN7O7. Mole weight: 511.5. | |
| Calcium Phosphate | Calcium phosphate was used as an adjuvant in France in diphtheria, tetanus, pertussis, and poliomyelitis vaccines. Synonyms: Phosphoric acid, calcium salt (1:x); Phosphoric acid, calcium salt; Budal MW 500; Calcium phosphate; Crodax DP 30; Dikal 21; Dynafos; E 341; Halox 430; HAP 05NP; HAP 60NPG; KDV 15u; LF-CP-ZA; Man-Gill 51504; Mecahl P; Mekaru P; Osteon GBC0305; Toppufuro K. Grades: 95%. CAS No. 10103-46-5. Molecular formula: Ca.xH3O4P. Mole weight: 97.99 (free acid). | |
| c-di-IMP | c-diIMP is an analogue of c-diAMP and c-diGMP, the bacterial second messengers, which is potentially used as an adjuvant for mucosal vaccination. Synonyms: Cyclic diinosine monophosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 79940-41-3. Molecular formula: C20H22N8O14P2 (free acid). Mole weight: 660.4 (free acid). | |
| Chamigrenal | Chamigrenal, a pharmacological treatment of anxiety disorders, intricately works towards ameliorating the perturbed functioning of the GABA receptors that ensue due to the hyperactivity of the brain. The convoluted mechanism of action mediates a stupor gently and minimizes the manifestation of anxiety symptoms. Additionally, it occasionally serves as an adjuvant in the management of insomnia. Synonyms: Spiro[5.5]?undec-2-ene-3-carboxaldehyde, 7,?7-dimethyl-11-methylene-, (-)?-. Grades: >98%. CAS No. 19912-84-6. Molecular formula: C15 H22 O. Mole weight: 218.33. | |
| Chitosan | Chitosan is a deacetylated derivative of chitin. Chitosan is a polysaccharide present in the exoskeleton of a variety of crustaceans and cell walls of fungi. It can be used in the medical field and cosmetics manufacturing. In addition to its role in drug delivery, chitosan can also act as an adjuvant due to its immune-stimulating activity. Chitosan stimulates the immune system by activating the NLRP3 inflammasome, which produces potent IL-1b. When tested in an experimental model of vaccination, chitosan elicits a balanced Th1/Th2 response. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Deacetylated chitin; Poly(D-glucosamine); Poly-b-(1,4)-2-Amino-2-deoxy-D-glucose; 2-Amino-2-deoxy-(1,4)-b-D-glucopyranan; deacetylchitin; b-1,4-poly-D-glucosamine; poly-D-glucosamine; poly-(1,4-b-D-glucopyranosamine). Grades: DAC degree?90%+. CAS No. 9012-76-4. Molecular formula: [C7H15NO4]n. Mole weight: 60-120 kDa. | |
| Cimetidine | Cimetidine, a histamine congener, competitively inhibits histamine binding to histamine H2 receptors. Uses: Adjuvants, immunologic; analgesics, non-narcotic; anti-ulcer agents; enzyme inhibitors; histamine h2 antagonists. Synonyms: SKF-92334; SKF 92334; SKF92334. Grades: >98%. CAS No. 51481-61-9. Molecular formula: C10H16N6S. Mole weight: 252.34. | |
| Clenbuterol(N) (HRP) | Clenbuterol belongs to the group of agonists. In livestock production clenbuterol improves the meat/fat ratio in fattened animals or accelerate the growth. Up to now agonists have not been authorized as adjuvants for fattening. In addition to its lipolytic and anabolic effect, clenbuterol has a relaxing effect on non-striated musculature on which is based its therapeutic use as an antiasthmatic and a tocolytic agent. When employed as a fattening adjuvant, as compared with the therapeutic use, clenbuterol is administered in a 5 to 10 times higher dose. Therefore, it is possible that clenbuterol residues may lead to a risk for consumers after illegal administration.Using the clenbuterol monocalantibody, it is possible to detect clenbuterol and other agonists in urine, muscle and liver both rapidly and with accuracy. Group: Biochemicals. Grades: Purified. Pack Sizes: 500ul. US Biological Life Sciences. | Worldwide |
| CS 2100 | CS 2100 has been found to be a S1P1 agonist and exhibit activities in animal's adjuvant-induced arthritis model. Synonyms: CS-2100; CS 2100; CS2100. 1-[[4-Ethyl-5-[5-(4-phenoxyphenyl)-1,2,4-oxadiazol-3-yl]-2-thienyl]methyl]-3-azetidinecarboxylic acid. Grades: ≥97% by HPLC. CAS No. 913827-99-3. Molecular formula: C25H23N3O4S. Mole weight: 461.53. | |
| DBM 1285 dihydrochloride | DBM 1285 dihydrochloride is a p38 MAPK inhibitor supressing p38 phosphorylation and LPS-induced TNF-α production in macrophages and in vivo. It was shown to attenuate zymosan-induced inflammation and adjuvant-induced arthritis in murine models. Synonyms: DBM 1285 dihydrochloride; DBM1285 dihydrochloride; DBM-1285 dihydrochloride; N-Cyclopropyl-4-[4-(4-fluorophenyl)-2-(4-piperidinyl)-5-thiazolyl]-2-pyrimidinamine dihydrochloride. Grades: ≥98% by HPLC. CAS No. 1782532-29-9. Molecular formula: C21H22FN5S.2HCl. Mole weight: 468.42. | |
| Delta Inulin | Delta Inulin. CAS No. 9005-80-5. Product ID: 8-05072. Molecular formula: (C6H10O5)n. Mole weight: [162.14]n. Properties: adjuvant. Reference: Sci Rep 7, 8582, 2017; Mucosal Immunol 14, 762-773, 2021, Mucosal Immunol 15, 1405-1415, 2022. |  |
| Dextran sulfate | Dextran sulfate. CAS No. 9011-18-1. Product ID: 4-00038. Mole weight: Mw 40,000. Properties: Inhibits virus growth and cell aggregation, acts as adjuvant, and precipitates serum lipoproteins, suited for nucleic acid hybridizations; displays anti-HIV activity. Reference: Br. J. Nutr.; 76, 797, 1996; Carbohydr. Polym., 25, 331, 1994; Chemistry and Biology of (1,3)-b-Glucans, B. A. Stone and A. E. Clarke, La Trobe University Press, Australia, 1992. | |
| Diallyl thiosulfinate | Source from bulb of Allium sativum L. Extracts of fresh garlic are more potent inhibitors of Staphylococcus epidermidis biofilms than pure Allicin, but Allicin exerts a unique bactericidal effect on biofilm-embedded bacteria. It could have clinical applications in controlling P. mirabilis infections. The beneficial role of Allicin as an adjuvant to Tamoxifen in cancer treatment by alleviating liver injury. Uses: Antibacterial anti-inflammatory, for a variety of pathogenic bacteria has high bactericidal activity. Synonyms: Allicin; 2-Propene-1-sulfinothioic Acid S-2-Propen-1-yl Ester; Allimed; Alliosan; Allisure Liquid; Thio-2-propene-1-sulfinic Acid S-Allyl Ester; S-allyl prop-2-ene-1-sulfinothioate; Diallyldisulfid-S-oxid; Allylthiosulphinic acid allyl ester; DADSO; S-Allyl acrylo-1-sulphinothioate; S-allyl 2-propene-1-sulfinothioate; 3-prop-2-enylsulfinylsulfanylprop-1-ene. Grades: >98%. CAS No. 539-86-6. Molecular formula: C6H10OS2. Mole weight: 162.26. | |
| dI-CPG 1000 | dI-CPG 1000, a powerful synthetic immunostimulatory oligonucleotide that serves to activate the natural immune system. Its unique ability to act as a Toll-like receptor 9 (TLR9) agonist initiates the production of an array of cytokines and chemokines, which in turn create a domino effect that stimulates immune responses effectively. Its extensive application in cancer immunotherapy as an adjuvant and also as a vaccine adjuvant against a vast range of infectious diseases amplifies its importance in the scientific community. Synonyms: 5'-Dimethoxytrityl-2'-deoxyInosine, 3'-succinoyl-long chain alkylamino-CPG 1000. Mole weight: 314.19. | |
| dI-CPG 500 | dI-CPG 500, a fascinating synthetic molecule, is widely acknowledged as an immunostimulatory agent, leveraging Toll-like receptor 9 (TLR9) signaling to trigger immune responses in different cell types. Scientific studies propose dI-CPG 500's potential ability to be utilized as an adjuvant in cancer immunotherapy, with an emphasis on using it to treat ovarian and breast cancer. Moreover, research suggests that the molecule showcases promising prospects of treating infectious diseases such as hepatitis B and C and herpes simplex virus. Synonyms: 5'-Dimethoxytrityl-2'-deoxyInosine, 3'-succinoyl-long chain alkylamino-CPG 500. Mole weight: 314.19. | |
| Difucosyllacto-N-hexaose (b) | Difucosyllacto-N-hexaose (b) is a compound widely employed sector, used for studying a plethora of afflictions, including cancer and viral infections. As an adjuvant, this compound exerts its influence by amplifying the immune response, thus rendering it indispensable in the realm of drug discovery for immunotherapy and vaccine formulation. Synonyms: DFLNH (b); Cluster Lewis x-Lewis a octasaccharide branched. Molecular formula: C52H88N2O39. Mole weight: 1365.25. | |
| Ditiocarb sodium | Ditiocarb sodium (Sodium diethyldithiocarbamate) is a copper reagent. The reaction with Cu 2+ solution resulted in the formation of a complex, which increased the copper displacement precipitation rate. Ditiocarb sodium can reduce HIV infection and can be used in adjuvant immune research of high-risk breast cancer [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Sodium diethyldithiocarbamate. CAS No. 148-18-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B1637. | |
| D-Mannuronic acid sodium | D-Mannuronic acid sodium, isolated from Macrocystis pyrifera , has the potential in autoimmune encephalomyelitis (EAE), adjuvant induced arthritis (AIA), nephrotic syndrome, and acute glomerulonephritis studies [1]. Uses: Scientific research. Group: Natural products. CAS No. 921-56-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N7703. | |
| DOTAP | DOTAP is a cationic lipid structure, used for in vitro and in vivo nucleic acid and protein delivery. DOTAP is a good immunomodulator, the antigen presenting capacity of antigen presenting cells can be obviously improved by preparing cationic liposome by packaging polypeptide or protein antigens and the DOTAP, and the DOTAP can activate the antigen presenting cells through a mitogen-activated protein kinase (MAP) pathway to induce specific immune response, unlike the traditional adjuvant which activates the antigen presenting cells through a Toll-like receptor pathway. Synonyms: 1,2-Dioleoyloxy-3-(trimethylammonium)propane; 1,2-Dotap; N,N,N-Trimethyl-2,3-bis((-1-oxo-octadecenyl)oxy)-(Z,Z)-1-propanaminium; N,N,N-Trimethyl-2,3-bis(oleoyloxy)propan-1-aminium. CAS No. 113669-21-9. Molecular formula: C42H80NO4. Mole weight: 663.09. | |
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