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| Product | Description | |
|---|---|---|
| ADPS | ADPS is a kind of new Trinder's reagents, which are high water-soluble aniline derivatives, widely used in diagnostic and biochemical tests. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: ESPAS. CAS No. 82611-88-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-15904. |  |
| ADPS | It is a novel Trinder's reagent used as a water-soluble reagent for the determination of hydrogen peroxide by enzyme spectrophotometry, and is widely used in diagnostic detection and biochemical test. Synonyms: N-Ethyl-N-(3-sulfopropyl)-3-methoxyaniline sodium salt; 3-[Ethyl(3-methoxyphenyl)amino]-1-propanesulfonic Acid Sodium Salt; N-Ethyl-N-(3-sulfopropyl)-m-anisidine Sodium Salt. Grades: ≥ 95 %. CAS No. 82611-88-9. Molecular formula: C12H18NNaO4S. Mole weight: 295.33. |  |
| N-Ethyl-N-(3-sulfopropyl)-3-methoxyaniline sodium salt | N-Ethyl-N-(3-sulfopropyl)-3-methoxyaniline sodium salt. Group: Biochemicals. Alternative Names: ADPS. Grades: Highly Purified. CAS No. 82611-88-9. Pack Sizes: 2g, 5g, 10g. Molecular Formula: C12H18NO4S·Na. US Biological Life Sciences. |  Worldwide |
| (1-{1'-Adamantyl}-1-methyl-ethoxycarbonyl)-L-tryptophan | Synonyms: Adpoc-L-Trp-OH. Grades: 95%. CAS No. 68388-91-0. Molecular formula: C25H32N2O4. Mole weight: 424.54. | |
| 1,2-diepi-ent-Ticagrelor | 1,2-diepi-ent-Ticagrelor is the 1,2-diepi enantiomer of Ticagrelor (T437700); the first reversible oral P2Y12 receptor antagonist that provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C23H28F2N6O4S, Molecular Weight: 522.57. US Biological Life Sciences. | Worldwide |
| 1,2-diepi-ent-Ticagrelor-d7 | 1,2-diepi-ent-Ticagrelor-d7 is the isotope labelled analog of 1,2-diepi-ent-Ticagrelor (T437705); the 1,2-diepi enantiomer of Ticagrelor (T437700) which is the first reversible oral P2Y12 receptor antagonist that provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 5mg. Molecular Formula: C23H21D7F2N6O4S, Molecular Weight: 529.61. US Biological Life Sciences. | Worldwide |
| 1, ?2-?Piperidinedicarboxyl ?ic Acid 1-?(Phenylmethyl) Ester | 1, ?2-?Piperidinedicarboxyl ?ic Acid 1-?(Phenylmethyl) Ester is used to prepare disubstituted azetidinones as selective inhibitors of cysteine protease cathepsin K. It is also used to synthesize 2-?[(R)?-?2-?methylpyrrolidin-?2-?yl]?-?1H-?benzimidazole-?4-?carboxamide (ABT-?888) as the Poly(ADP-?ribose) Polymerase (PARP) inhibitor for the treatment of cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 28697-07-6. Pack Sizes: 25g, 100g. Molecular Formula: C14H17NO4, Molecular Weight: 263.29. US Biological Life Sciences. | Worldwide |
| 15-deoxy-Δ12,14-Prostaglandin D2 | 15-deoxy-Δ12,14-Prostaglandin D2 (15-Deoxy-Δ12,14-PGD2), a metabolite of PGD2 (HY-101988), is an agonist of prostaglandin receptor 2 (DP2). 15-deoxy-Δ12,14-Prostaglandin D2 binds to DP2 (Ki=50 nM) and induces eosinophil activation ( EC 50 =8 nM). 15-deoxy-Δ12,14-Prostaglandin D2 also stimulates the recruitment of steroid receptor coactivator-1 ( SRC-1 ) to peroxisome proliferator-activated receptor γ ( PPARγ ), inducing PPARγ-mediated transcription. 15-deoxy-Δ12,14-Prostaglandin D2 (15-Deoxy-Δ12,14-PGD2) is cytotoxic to L1210 murine leukemia cells ( IC 50 =0.3 μg/ml) and inhibits ADP-induced platelet aggregation ( IC 50 =320 ng/mL). Uses: Scientific research. Group: Signaling pathways. Alternative Names: 15-Deoxy-Δ12,14-PGD2. CAS No. 85235-11-6. Pack Sizes: 1 mg (2.99 mM * 1 mL in Methyl acetate). Product ID: HY-116028. | |
| 1,5-Isoquinolinediol | 1,5-Isoquinolinediol is a PARP1 inhibitor (IC50 value 0.39 - 1.00 μM) and neuroprotective agent leading to an increase up to 8-fold in the absolute frequency of gene targeting in the correction of the mutation at the stable integrated HSV tk gene in mouse Ltk cells. 1,5-Isoquinolinediol is also an inducible nitric oxide synthase (NOS2) inhibitor. 1,5-Isoquinolinediol significantly inhibited mitochondrial membrane potential loss, AIF (apoptosis inducing factor) and cytochrome c release from the mitochondria. Uses: Poly(adp-ribose) polymerase inhibitors. Synonyms: 1,5-Dihydroxyisoquinoline; Isoquinoline-1,5-diol; 5-Hydroxy-1(2H)-isoquinolinone; 5-Hydroxyisocarbostyril. Grades: 99%. CAS No. 5154-2-9. Molecular formula: C9H7NO2. Mole weight: 161.16. | |
| 1-? (Benzyloxycarbonyl) ?pyrrolidine-?3-?carboxylic Acid | 1-? (Benzyloxycarbonyl) ?pyrrolidine-?3-?carboxylic Acid is a reagent used in the synthesis of cyclin-dependent kinase 4-inhibitors (CDK4) for cancer treatments. Also used towards the discovery of a potent inhibitor of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer pased upon benzimidazole carboxamide moieties. Group: Biochemicals. Grades: Highly Purified. CAS No. 188527-21-1. Pack Sizes: 100mg, 250mg. Molecular Formula: C13H15NO4, Molecular Weight: 249.26. US Biological Life Sciences. | Worldwide |
| 1,N6-Ethenoadenosine-5'-diphosphate, Sodium salt | 1,N6-Ethenoadenosine-5'-diphosphate, Sodium salt. Group: Biochemicals. Alternative Names: Etheno-ADP. Grades: Highly Purified. CAS No. 103213-52-1. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C12H15N5O10P2. US Biological Life Sciences. | Worldwide |
| 1,N6-Ethenoadenosine-5'-diphosphate, Sodium salt | 1,N6-Ethenoadenosine-5'-diphosphate, Sodium salt is a P2Y2 and P2Y6 receptor agonist, used in studying purinergic signaling mechanisms. It is also utilized in research and development targeting ureteral obstruction and pulmonary diseases. Synonyms: Etheno-ADP; sodium ((2R,3S,4R,5R)-3,4-dihydroxy-5-(3H-imidazo[1,2-i]purin-3-yl)tetrahydrofuran-2-yl)methyl diphosphate. Grades: ≥98%. CAS No. 103213-52-1. Molecular formula: C12H12N5Na3O10P2. Mole weight: 517.17. | |
| (1R,2R)-2-(3,4-Difluorophenyl)-cyclopropanecarbonyl Azide | (1R,2R)-2-(3,4-Difluorophenyl)-cyclopropanecarbonyl Azide is a useful synthetic intermediate in the synthesis of Ticagrelor (T437700); the first reversible oral P2Y12 receptor antagonist that provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is also used in the treatment of acute coronary syndromes (ACS). Group: Biochemicals. Grades: Highly Purified. CAS No. 378236-67-0. Pack Sizes: 5mg, 50mg. Molecular Formula: C10H7F2N3O, Molecular Weight: 223.18. US Biological Life Sciences. | Worldwide |
| (1R, 2R) -2- (3, 4-Difluorophenyl) cyclopropane carboxamide | (1R, 2R) -2- (3, 4-Difluorophenyl) cyclopropane carboxamide is a part of the synthetic preparation of the synthesis and inhibitory effect on ADP-induced platelet aggregation of ticagrelor derivatives as antiplatelets agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 1006376-62-0. Pack Sizes: 50mg, 100mg. Molecular Formula: C10H9F2NO, Molecular Weight: 197.181. US Biological Life Sciences. | Worldwide |
| (1S, 2S, 3R, 5S) -3- ( (6-Chloro-5- ( (3- ( (1R, 2S, 3S, 4S) -2, 3-dihydroxy-4- (2-hydroxyethoxy) cyclopentyl) -5- (propylthio) -3H-[1, 2, 3]triazolo[4, 5-d]pyrimidin-7-yl) amino) -2- (propylthio) pyrimidin-4-yl) amino) -5- (2-hydroxyethoxy) cyclopentane-1, 2-diol | (1S, 2S, 3R, 5S) -3- ( (6-Chloro-5- ( (3- ( (1R, 2S, 3S, 4S) -2, 3-dihydroxy-4- (2-hydroxyethoxy) cyclopentyl) -5- (propylthio) -3H-[1, 2, 3]triazolo[4, 5-d]pyrimidin-7-yl) amino) -2- (propylthio) pyrimidin-4-yl) amino) -5- (2-hydroxyethoxy) cyclopentane-1, 2-diol is pyrimidine dimer impurity of Ticagrelor (T437700), which is the first reversible oral P2Y12 receptor antagonist that provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C28H42ClN9O8S2, Molecular Weight: 732.27. US Biological Life Sciences. | Worldwide |
| (1S,2S,3R,5S)-3-[7-Chloro-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol | (1S,2S,3R,5S)-3-[7-Chloro-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol is an intermediate in the synthesis of metaboltes of Ticagrelor (T437700) which is the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Group: Biochemicals. Grades: Highly Purified. CAS No. 1354945-69-9. Pack Sizes: 100mg, 250mg. Molecular Formula: C14H20ClN5O4S. US Biological Life Sciences. | Worldwide |
| (1S, 2S, 3R, 5S) -3-Amino-5- (2-hydroxyethoxy) cyclopentane-1, 2-diol Hydrochloride | (1S, 2S, 3R, 5S) -3-Amino-5- (2-hydroxyethoxy) cyclopentane-1, 2-diol Hydrochloride is used in the synthesis of Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg, 250mg. Molecular Formula: C7H16ClNO4, Molecular Weight: 213.66. US Biological Life Sciences. | Worldwide |
| (1S,2S,3S,5R)-3-(2-Hydroxyethoxy)-5-[7-methoxy-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-1,2-cyclopentanediol | (1S,2S,3S,5R)-3-(2-Hydroxyethoxy)-5-[7-methoxy-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-1,2-cyclopentanediol is an intermediate in the synthesis of (1S,2S,3R,5S)-3-[7-Chloro-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol which is used in preparation of metaboltes of Ticagrelor (T437700) which is the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Group: Biochemicals. Grades: Highly Purified. CAS No. 2024557-22-8. Pack Sizes: 250mg, 500mg. Molecular Formula: C15H23N5O5S. US Biological Life Sciences. | Worldwide |
| 1S-epi-Ticagrelor | 1S-epi-Ticagrelor is an impurity of Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C23H28F2N6O4S, Molecular Weight: 522.57. US Biological Life Sciences. | Worldwide |
| 1-Tritylpiperidin-4-one | 1-Tritylpiperidin-4-one is an intermediate in the synthesis of trans R-138727, (Prasugrel Metabolite) (R070195), which is the active metabolite of Prasugrel; inhibits ADP-stimulated thrombo-inflammatory markers of platelet activation: influence of other blood cells, calcium, and aspirin. Group: Biochemicals. Grades: Highly Purified. CAS No. 112257-60-0. Pack Sizes: 100mg, 500mg. Molecular Formula: C24H23NO. US Biological Life Sciences. | Worldwide |
| 2-[1-(4,4-Difluorocyclohexyl)-4-piperidinyl]-6-fluoro-2,3-dihydro-3-oxo-1H-isoindole-4-carboxamide | 2-[1-(4,4-Difluorocyclohexyl)-4-piperidinyl]-6-fluoro-2,3-dihydro-3-oxo-1H-isoindole-4-carboxamide is a nuclear protein poly(ADP-ribose) polymerase-1 (PARP-1) inhibitor. PARP-1 is involved with the signaling and repair of DNA and a target in oncology. Group: Biochemicals. Grades: Highly Purified. CAS No. 1262417-51-5. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C20H24F3N3O2, Molecular Weight: 395.42. US Biological Life Sciences. | Worldwide |
| 2-[[(3aR,4R,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol (R,R)-Tartrate Salt | 2-[[(3aR,4R,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol (R,R)-Tartrate Salt is an impurity of Ticagrelor (T437700). Ticagrelor, the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 10mg. Molecular Formula: C14H25NO10, Molecular Weight: 367.35. US Biological Life Sciences. | Worldwide |
| 2-((3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yloxy)ethanol L-tartaric acid | An impurity of Ticagrelor which rapidly produced and maintained greater inhibition of adenosine diphosphate (ADP)-induced platelet aggregation compared with clopidogrel without increasing major bleeding risk. Synonyms: 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]-ethanol (2R,3R)-2,3-dihydroxybutanedioate; (2R,3R)-2,3-dihydroxybutanedioic acid; 2-{[(3aR,4S,6R,6aS)-6-amino-2,2-dimethyl-hexahydrocyclopenta[d][1,3]dioxol-4-yl]oxy}ethan-1-ol. CAS No. 376608-65-0. Molecular formula: C14H25NO10. Mole weight: 367.35. | |
| 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol | 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol is an enantiomer of an intermediate for Ticagrelor, which is the first reversible oral P2Y12 receptor antagonist that provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C10H19NO4, Molecular Weight: 217.26. US Biological Life Sciences. | Worldwide |
| 2,3-DCPE hydrochloride | 2,3-DCPE hydrochloride is a compound that selectively induces apoptosis and downregulates Bcl-XL protein expression in multiple human cancer cells versus normal cells in vitro. It also specifically cleaves caspase-8, caspase-3, caspase-9, and poly(ADP-ribose) polymerase in cancer cells. Uses: Antitumor agent. Synonyms: 2,3-DCPE HCl; 2-((3-(2,3-Dichlorophenoxy)propyl)amino)ethan-1-ol hydrochloride. Grades: ≥99% by HPLC. CAS No. 1009555-55-8. Molecular formula: C11H16Cl3NO2. Mole weight: 300.61. | |
| 2,?3-?Diaminobenzamide Dihydrochloride | 2,?3-?Diaminobenzamide Dihydrochloride can be used in synthesis and evaluation of (heteroaryl phenyl ) benzimidazolecarboxami de s as orally efficacious poly(ADP-ribose) polymerase-1 inhibitors and anticancer agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 266993-72-0. Pack Sizes: 25mg, 50mg. Molecular Formula: C7H9N3O; 2(HCl), Molecular Weight: 151.1723646. US Biological Life Sciences. | Worldwide |
| 2,3-Isopropylidene Adenosine-13C5 | 2,3-Isopropylidene Adenosine-13C5 is an intermediate in the synthesis of Adenosine 5-Diphosphate-13C5 Ammonium Salt Hydrate (A281697), which is the isotope labelled analog of Adenosine 5-Diphosphate Ammonium Salt Hydrate (A281700); a nucleoside diphosphate that interacts with a family of ADP receptors found on platelets (P2Y1, P2Y12 and P2X1), to induce platelet activation. ADP in the blood is converted to adenosine by the action of ecto-ADPases, inhibiting further platelet activation via adenosine receptors. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C813C5H17N5O4. US Biological Life Sciences. | Worldwide |
| 2'/3'-O-Acetyl ADP Ribose-d3. (A mixture of 2'/3'-O-Acetyl ADP Ribose-d3) | 2'/3'-O-Acetyl ADP Ribose-d3(A mixture of 2'/3'-O-Acetyl ADP Ribose-d3). Group: Biochemicals. Alternative Names: Adenosine 5'-(trihydrogen diphosphate) P'?5-Ester with D-ribose 2-Acetate-d3 Sodium Salt (1:2). Grades: Highly Purified. Pack Sizes: 500ug. Molecular Formula: C17H20D3N5Na2O15P2, Molecular Weight: 648.33. US Biological Life Sciences. | Worldwide |
| 2'/3'-O-Acetyl ADP Ribose, Disodium Salt(A mixture of 2' and 3'-O-Acetyl ADP Ribose) | 2'/3'-O-Acetyl ADP Ribose, are the metabolites produced from NAD as a product of sirtuin-mediated protein deacetylation. Synonyms: Adenosine 5'-(trihydrogen diphosphate) P'?5-Ester with D-ribose 2-Acetate Sodium Salt (1:2). Grades: 95%. CAS No. 1312013-29-8. Molecular formula: C17H23N5Na2O15P2. Mole weight: 645.32. | |
| 2',3'-O-Isopropylidene-5'-O-tosyladenosine | 2',3'-O-Isopropylidene-5'-O-tosyladenosine is an intermediate in the synthesis of Adenosine 5-Diphosphate-13C5 Ammonium Salt Hydrate (A281697), which is the isotope labelled analog of Adenosine 5-Diphosphate Ammonium Salt Hydrate (A281700); a nucleoside diphosphate that interacts with a family of ADP receptors found on platelets (P2Y1, P2Y12 and P2X1), to induce platelet activation. ADP in the blood is converted to adenosine by the action of ecto-ADPases, inhibiting further platelet activation via adenosine receptors. Group: Biochemicals. Grades: Highly Purified. CAS No. 5605-63-0. Pack Sizes: 2.5g, 5g. Molecular Formula: C20H23N5O6S. US Biological Life Sciences. | Worldwide |
| 2',3'-O-Isopropylidene-5'-O-tosyladenosine-13C5 | 2',3'-O-Isopropylidene-5'-O-tosyladenosine-13C5 is an intermediate in the synthesis of Adenosine 5-Diphosphate-13C5 Ammonium Salt Hydrate (A281697), which is the isotope labelled analog of Adenosine 5-Diphosphate Ammonium Salt Hydrate (A281700); a nucleoside diphosphate that interacts with a family of ADP receptors found on platelets (P2Y1, P2Y12 and P2X1), to induce platelet activation. ADP in the blood is converted to adenosine by the action of ecto-ADPases, inhibiting further platelet activation via adenosine receptors. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C1513C5H23N5O6S. US Biological Life Sciences. | Worldwide |
| 2',3'-O-(N-Methylanthraniloyl)-adenosine-5'-diphosphate triethylammonium salt | 2',3'-O-(N-Methylanthraniloyl)-adenosine-5'-diphosphate triethylammonium salt is an accomplished antagonist of P2Y1, assuming a pivotal role in research of cardiovascular perspicacity. Synonyms: MANT-ADP. Molecular formula: C18H22N6O11P2. Mole weight: 560.35. | |
| 2-(4-Hydroxyphenyl)-1H-benzimidazole-7-carboxamide | 2-(4-Hydroxyphenyl)-1H-benzimidazole-7-carboxamide is a poly(ADP-ribose) polymerase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 188106-83-4. Pack Sizes: 100mg, 250mg. Molecular Formula: C14H11N3O2, Molecular Weight: 253.26. US Biological Life Sciences. | Worldwide |
| 2-?Chloro-?1-?(3-?fluorobenzyloxy)?-?4-?nitrobenzene | 2-?Chloro-?1-?(3-?fluorobenzyloxy)?-?4-?nitrobenzene is a reagent used in the synthesis of novel indole-2-carboxamide derivative as anti-inflammatory agents used in the treatment of sepsis. Also an intermediate of Niraparib (N481400), a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors. Group: Biochemicals. Grades: Highly Purified. CAS No. 443882-99-3. Pack Sizes: 5g, 10g. Molecular Formula: C13H9ClFNO3, Molecular Weight: 281.67. US Biological Life Sciences. | Worldwide |
| 2-Chlorobenzylamine | An impurity of Ticlopidine which is believed to inhibit the binding of adenosine 5'-diphosphate (ADP) to its platelet receptor. Synonyms: (2-chlorophenyl)methanamine. Grades: > 95 %. CAS No. 89-97-4. Molecular formula: C7H8ClN. Mole weight: 141.60. | |
| 2-Cl-ADP | 2-Cl-ADP is an analogue of adenosine-5'-diphosphate and a precursor for 2-modified ADP derivatives. Synonyms: 2- Chloroadenosine- 5'- O- diphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 16506-88-0. Molecular formula: C10H14ClN5O10P2 (free acid). Mole weight: 461.7 (free acid). | |
| (2E)-2-[1-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4-mercapto-3-piperidinylidene]-acetic Acid Ethyl Ester Hydrochloride | (2E)-2-[1-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4-mercapto-3-piperidinylidene]-acetic Acid Ethyl Ester Hydrochloride is an intermediate in the synthesis of trans R-138727, (Prasugrel Metabolite) (R070195), which is the active metabolite of Prasugrel; inhibits ADP-stimulated thrombo-inflammatory markers of platelet activation: influence of other blood cells, calcium, and aspirin. Group: Biochemicals. Grades: Highly Purified. CAS No. 204206-07-5. Pack Sizes: 500ug, 1mg. Molecular Formula: C20H24FNO3S; (HCl), Molecular Weight: 377.473645999999. US Biological Life Sciences. | Worldwide |
| (2E)-[4-Bromo-1-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-3-piperidinylidene]-acetic Acid Ethyl Ester | (2E)-[4-Bromo-1-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-3-piperidinylidene]-acetic Acid Ethyl Ester is an intermediate in the synthesis of trans R-138727, (Prasugrel Metabolite) (R070195), which is the active metabolite of Prasugrel; inhibits ADP-stimulated thrombo-inflammatory markers of platelet activation: influence of other blood cells, calcium, and aspirin. Group: Biochemicals. Grades: Highly Purified. CAS No. 239466-57-0. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C20H23BrFNO3, Molecular Weight: 424.3. US Biological Life Sciences. | Worldwide |
| 2-Ethynyl-ATP (2-EATP) | 2-Ethynyl-ATP (2-EATP), a modified nucleotide, finds its utility in enzymatic assays intended to scrutinize ATP-binding proteins, namely kinases and phosphatases. It also serves as a powerful instrument to investigate ATP-dependent enzymes implicated in numerous pathological conditions, viz. cancer and neurological disorders. Synonyms: 2-Ethynyl-adenosine-5'-triphosphate, Sodium salt. Grades: ≥ 90% by HPLC, contains approx. 6% 2-Ethynyl-ADP. Molecular formula: C12H16N5O13P3. Mole weight: 531.2. | |
| 2-Fluoro-5-[ (3-oxo-1 (3H) -isobenzofuranylidene) methyl]-benzonitrile | Intermediate in the preparation of poly (ADP-ribose) polymerase (PARP) inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 763114-25-6. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 2-Fluoro-5-(4-oxo-3,4-dihydrophthalazin-1-ylmethyl)benzoic Acid | 2-Fluoro-5-(4-oxo-3,4-dihydrophthalazin-1-ylmethyl)benzoic Acid is an intermediate used in the synthesis of phthalazinone scaffolds that are potent inhibitors of poly(ADP-ribose) polymerase, and also in the design of isocorydine derivatives with anticancer effect. Group: Biochemicals. Grades: Highly Purified. CAS No. 763114-26-7. Pack Sizes: 250mg, 500mg. Molecular Formula: C16H11FN2O3, Molecular Weight: 298.27. US Biological Life Sciences. | Worldwide |
| 2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzonitrile | 2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzonitrile is an intermediate used in the synthesis of phthalazinone scaffolds that are potent inhibitors of poly(ADP-ribose) polymerase. Group: Biochemicals. Grades: Highly Purified. CAS No. 1021298-68-9. Pack Sizes: 25mg, 250mg. Molecular Formula: C16H10FN3O, Molecular Weight: 279.27. US Biological Life Sciences. | Worldwide |
| 2-MeS-5'-AMP | 2-MeS-5'-AMP is a potent antagonist of adenylate cyclase-coupled platelet ADP P2Y purinoceptor. Synonyms: 2- Methylthioadenosine- 5'- O- monophosphate, sodium salt. Grades: ≥ 97% by HPLC. CAS No. 22140-20-1. Molecular formula: C11H16N5O7PS (free acid). Mole weight: 393.3 (free acid). | |
| 2-MeS-ADP | 2-MeS-ADP is an agonist of P2Y1, P2Y12 and P2Y13 receptors. Synonyms: 2-Methylthio-adenosine-5'-diphosphate; 2-MeSADP; 2MeSADP; 2-methylthio-ADP. Grades: ≥ 95% by HPLC. CAS No. 34983-48-7. Molecular formula: C11H17N5O10P2S (free acid). Mole weight: 473.30. | |
| 2-Methylcitric acid | 2-Methylcitric acid (Methylcitric acid) is an endogenous metabolite in the 2-methylcitric acid cycle. 2-Methylcitric acid accumulates in methylmalonic and propionic acidemias and acts as a marker metabolite. 2-Methylcitric acid markedly inhibits ADP-stimulated and uncoupled respiration in mitochondria supported by glutamate [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Methylcitric acid. CAS No. 6061-96-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-113371. | |
| 2-Methylthioadenosine | 2-Methylthioadenosine is an adenosine precursor to 2-MeS-ATP, 2-MeS-ADP and 2-MeS-AMP. Synonyms: 2-(Methylthio)adenosine; NSC 36900; (2R,3R,4S,5R)-2-(6-amino-2-(methylthio)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; Adenosine, 2-(methylthio)-; 2-MeS-adenosine. Grades: ≥95%. CAS No. 4105-39-9. Molecular formula: C11H15N5O4S. Mole weight: 313.33. | |
| 2-Methylthioadenosine diphosphate trisodium salt | 2-Methylthioadenosine diphosphate trisodium salt is a potent purinergic agonist displaying selectivity for P2Y1, P2Y12 and P2Y13 receptors (pEC50 = 8.29 and 9.05 for P2Y1 and P2Y12, EC50 = 19 nM for P2Y13), which induces platelet aggregation and shape change and inhibits cyclic AMP accumulation in platelets exposed to prostaglandin E1. Synonyms: 2-(Methylthio)adenosine-5'-(trihydrogen diphosphate) trisodium salt; 2-MeS-ADP; 2 MeS ADP; 2MeSADP; 2-Methylthio-ADP; 2 Methylthio ADP. Grades: ≥98% by HPLC. CAS No. 475193-31-8. Molecular formula: C11H14N5Na3O10P2S. Mole weight: 539.24. | |
| 2-Methylthio-ADP Trisodium Salt | 2-Methylthio-ADP trisodium salt is a P2Y1, P2Y12 and P2Y13 agonist. It is used in biological study of activation of P2Y1 P2Y12 and P2Y13 protein promoted purinergic ATP signal transduction mediated calcium flux in podocyte isolated from rat glomerulus. Group: Biochemicals. Alternative Names: 2-(Methylthio)adenosine 5'-Diphosphate Trisodium Salt; 2-MeSADP; 2-Methylthio-ADP. Grades: Highly Purified. CAS No. 475193-31-8. Pack Sizes: 10mg. Molecular Formula: C??H??N?Na?O??P?S, Molecular Weight: 539.24. US Biological Life Sciences. | Worldwide |
| 2'-NH2-ADP | 2'-NH2-ADP is a ligand in affinity chromatography and can be modified with fluorophores or other markers. Synonyms: 2'- Amino- 2'- deoxyadenosine- 5'- O- diphosphate. Grades: ≥ 95% by HPLC. CAS No. 63545-57-3. Molecular formula: C10H16N6O9P2 (free acid). Mole weight: 426.2 (free acid). | |
| 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase | This multiunctional enzyme catalyses both the removal of nicotinamide from NADP+, forming 2'-phospho-cyclic ADP-ribose, and the addition of nicotinate to the cyclic product, forming NAADP+, a calcium messenger that can mobilize intracellular Ca2+ stores and activate Ca2+ influx to regulate a wide range of physiological processes. In addition, the enzyme also catalyses EC 3.2.2.6, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase. Group: Enzymes. Synonyms: diphosphopyridine nucleosidase (ambiguous); CD38 (gene name); BST1 (gene name). Enzyme Commission Number: EC 2.4.99.20. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2705; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; EC 2.4.99.20; diphosphopyridine nucleosidase (ambiguous); CD38 (gene name); BST1 (gene name). Cat No: EXWM-2705. |  |
| 2'-phosphotransferase | Catalyses the final step of tRNA splicing in the yeast Saccharomyces cerevisiae. The reaction takes place in two steps: in the first step, the 2'-phosphate on the RNA substrate is ADP-ribosylated, causing the relase of nicotinamide and the formation of the reaction intermediate, ADP-ribosylated tRNA. In the second step, dephosphorylated (mature) tRNA is formed along with ADP ribose 1''-2''-cyclic phosphate. Highly specific for oligonucleotide substrates bearing an internal 2'-phosphate. Oligonucleotides with only a terminal 5'- or 3'-phosphate are not substrates. Group: Enzymes. Synonyms: yeast 2'-phosphotransferase; Tpt1; Tpt1p; 2'-phospho-tRNA:NAD+ phosphotransferase. Enzyme Commission Number: EC 2.7.1.160. CAS No. 126905-00-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2990; 2'-phosphotransferase; EC 2.7.1.160; 126905-00-8; yeast 2'-phosphotransferase; Tpt1; Tpt1p; 2'-phospho-tRNA:NAD+ phosphotransferase. Cat No: EXWM-2990. | |
| 2R-epi-Ticagrelor | 2R-epi-Ticagrelor is an impurity of Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C23H28F2N6O4S, Molecular Weight: 522.57. US Biological Life Sciences. | Worldwide |
| 3-Methoxybenzamide | 3-Methoxybenzamide is a competitive inhibitor of poly(ADP-ribose) synthetase with Ki values of less than 2 μM and also inhibits ADP-ribosyltransferase (ADPRT). Uses: Poly(adp-ribose) polymerase inhibitors. Synonyms: 3-methoxybenzamide. CAS No. 5813-86-5. Molecular formula: C8H9NO2. Mole weight: 151.16. | |
| 3-METHOXYBENZAMIDE | 3-Methoxybenzamide (3-MBA), an inhibitor of ADP-ribosyltransferase (ADPRTs) and PARP, inhibits cell division in Bacillus subtilis, leading to filamentation and eventually lysis of cells. 3-Methoxybenzamide (3-MBA) enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum). Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 5813-86-5. Molecular formula: C8H9NO2. Mole weight: 151.16. Purity: MP 132.5-135.5deg. Canonical SMILES: O=C(N)C1=CC=CC(OC)=C1. Product ID: ACM5813865. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 3'-NH2-ADP | 3'-NH2-ADP is a ligand in affinity chromatography and can be modified with fluorophores or other markers. Synonyms: 3'- Amino- 3'- deoxyadenosine- 5'- O- diphosphate. Grades: ≥ 95% by HPLC. CAS No. 4360-6-9. Molecular formula: C10H16N6O9P2 (free acid). Mole weight: 426.2 (free acid). | |
| 4-Amino-1,8-naphthalimide | The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species. 4-Amino-1,8-naphthalimide (4-ANI) is an inhibitor of PARP (IC50 = 180 nM). Synonyms: 4-Aminonaphthalimide; 4-ANI; 6-aminobenzo[de]isoquinoline-1,3-dione. Grades: ≥95%. CAS No. 1742-95-6. Molecular formula: C12H8N2O2. Mole weight: 212.2. | |
| 4H,5H,6H,7H-Thieno[3,2-c]pyridin-4-one | An impurity of Ticlopidine which is an orally P2 receptor inhibitor against ADP-induced platelet aggregation with IC50 of ~2 μM. Synonyms: 6,7-dihydro-5H-thieno[3,2-c]pyridin-4-one; 6,7-dihydro-5H-thieno[3,2-c]pyridin-4-one. Grades: > 95 %. CAS No. 68559-60-4. Molecular formula: C7H7NOS. Mole weight: 153.20. | |
| 4-Hydroxyquinazoline | 4-HQN is a poly(ADP-ribose) polymerase (PARP) inhibitor (IC50 = 9.5 μM). 4-HQN exhibits antianti-ischemic activity and reduces ROS production, subsequent mitochondrial and cell damage in rat heart. It also blocks NF-κB and AP-1 activation. Synonyms: 3H-quinazolin-4-one. Grades: ≥ 99 % by HPLC. CAS No. 491-36-1. Molecular formula: C8H6N2O. Mole weight: 146.15. | |
| 6-(1-MeBu)-ADP | 6-(1-MeBu)-ADP is a precursor in the synthesis of the corresponding radio-labelled triphosphate used in the chemical genetics approach. Grades: ≥ 95% by HPLC. Molecular formula: C15H25N5O10P2 (free acid). Mole weight: 497.3 (free acid). | |
| 6-(2-MeBu)-ADP | 6-(2-MeBu)-ADP is a precursor in the synthesis of the corresponding radio-labelled triphosphate used in the chemical genetics approach. Grades: ≥ 95% by HPLC. CAS No. 681175-77-9. Molecular formula: C15H25N5O10P2 (free acid). Mole weight: 497.3 (free acid). | |
| 6-(3-MeBn)-ADP | 6-(3-MeBn)-ADP is a precursor in the synthesis of the corresponding radio-labelled triphosphate used in the chemical genetics approach. Grades: ≥ 95% by HPLC. CAS No. 681175-78-0. Molecular formula: C18H23N5O10P2 (free acid). Mole weight: 531.4 (free acid). | |
| 6-AB-ADP | 6-AB-ADP is a ligand in affinity chromatography and can be modified with fluorophores or other markers. Synonyms: N6- (4- Aminobutyl)adenosine- 5'- O- diphosphate. Grades: ≥ 95% by HPLC. CAS No. 767272-34-4. Molecular formula: C14H24N6O10P2 (free acid). Mole weight: 498.3 (free acid). | |
| 6-Biotin-20-ADP | 6-Biotin-20-ADP, a nucleotide derivative deployed extensively in the realm of biomedicine, possesses a formidable repertoire of implications. This compound is an indispensable tool in studying the intricate interplay between proteins and nucleotides, especially when delving into the intricate binding proceedings of proteins to both ATP and ADP. Of significance, such inquiry holds a critical lens into the realm of pathology, touching on a gamut of neurodegenerative disorders in addition to the menacing shadow of cancer. Grades: ≥ 95% by HPLC. Molecular formula: C34H58N8O17P2S (free acid). Mole weight: 944.9 (free acid). | |
| 6-Biotin-4-ADP | 6-Biotin-4-ADP is an indispensable nucleotide with significant importance in energy metabolism by serving as a substrate for multiple enzymes. As the essential building block for ATP synthesis, 6-Biotin-4-ADP plays a vital role in producing and distributing energy throughout cells. Moreover, being utilized in the investigation of enzymes, especially those participating in carbohydrates, lipids, and proteins metabolism, this compound serves as an essential tool to provide insight into various biological processes. Grades: ≥ 95% by HPLC. Molecular formula: C23H36N8O12P2S (free acid). Mole weight: 710.6 (free acid). | |
| 6-cHe-ADP | 6-cHe-ADP is a precursor in the synthesis of the corresponding radio-labelled triphosphate used in the chemical genetics approach. Grades: ≥ 95% by HPLC. Molecular formula: C16H25N5O10P2 (free acid). Mole weight: 509.3 (free acid). | |
| 6-Cl-PuDP | 6-Cl-PuDP is an analogue of adenosine-5'-diphosphate and can be used as a precursor for 6- modified ADP derivatives. Synonyms: 6- Chloropurine riboside- 5'- O- diphosphate. Grades: ≥ 95% by HPLC. CAS No. 59128-86-8. Molecular formula: C10H13ClN4O10P2 (free acid). Mole weight: 446.6 (free acid). | |
| 6-cPe-5'-AMP | 6-cPe-5'-AMP is an analogue of AMP and a potential metabolite of 6-cPe-ATP and 6-cPe-ADP. Grades: ≥ 97 % by HPLC. CAS No. 117778-38-8. Molecular formula: C15H22N5O7P (free acid). Mole weight: 415.3 (free acid). | |
| 6-cPe-ADP / cpADP | 6-cPe-ADP is a precursor in the synthesis of the corresponding radio-labelled triphosphate used in the chemical genetics approach. Grades: ≥ 95% by HPLC. CAS No. 681175-79-1. Molecular formula: C15H23N5O10P2 (free acid). Mole weight: 495.3 (free acid). | |
| 6-Fu-ADP | 6-Fu-ADP is a precursor of the corresponding radio-labelled triphosphate that can be used for studies on kinase-substrate relationships (chemical genetics approach). Grades: ≥ 95% by HPLC. Molecular formula: C15H19N5O11P2 (free acid). Mole weight: 507.3 (free acid). | |
| 6-Hydroxykaempferol 3,6-diglucoside | 6-Hydroxykaempferol 3,6-diglucoside is a flavonoid compound isolated and purified from the herbs of Chrysactinia tinctorius. It shows weak inhibitory effects on the adenosine 5'-diphosphate (ADP)- induced platelet aggregation. Synonyms: 4H-1-Benzopyran-4-one, 3,?6-bis(β-D-glucopyranosyloxy)?-5,?7-dihydroxy-2-(4-hydroxyphenyl)?-. Grades: > 98%. CAS No. 142674-16-6. Molecular formula: C27H30O17. Mole weight: 626.5. | |
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