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| Product | Description | |
|---|---|---|
| Afatinib | Afatinib (BIBW 2992) is an orally active, potent and irreversible dual specificity inhibitor of ErbB family ( EGFR and HER2 ), with IC 50 values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFR wt , EGFR L858R , EGFR L858R/T790M and HER2, respectively. Afatinib can be used for the research of esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC) and gastric cancer [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BIBW 2992. CAS No. 850140-72-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10261. |  |
| Afatinib | Afatinib irreversibly inhibits EGFR/HER2 including EGFR, EGFR(L858R), EGFR(L858R/T790M) and HER2. It is 100-fold more active against Gefitinib-resistant L858R-T790M EGFR mutant. Uses: Antineoplastic agents. Synonyms: 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-, (2E)-; (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide; BIBW 2992; Gilotrif; Giotrif; Tovok; (S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide. Grades: >98%. CAS No. 850140-72-6. Molecular formula: C24H25ClFN5O3. Mole weight: 485.94. |  |
| Afatinib-[d6] | Afatinib-[d6] is the labelled analogue of Afatinib. Afatinib is a medication approved for the treatment of metastatic non-small cell lung cancer (NSCLC) that has certain EGFR mutations. It acts via inhibiting EGFR and HER2. Synonyms: Afatinib-d6; (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide-d6; BIBW 2992-d6; Tovok-d6; Tomtovok-d6. Grades: 97%; ≥99% atom D. CAS No. 1313874-96-2. Molecular formula: C24H19D6ClFN5O3. Mole weight: 491.98. | |
| Afatinib-des(4-dimethylamino-2-en-1-oxo)butyl (Contained ~8.5% Ethanol) | Afatinib-des(4-dimethylamino-2-en-1-oxo)butyl is a reactant in the synthesis of Afatinib (A355300), an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder. Group: Biochemicals. Grades: Highly Purified. CAS No. 314771-76-1. Pack Sizes: 100mg, 1g. Molecular Formula: C18H16ClFN4O2. US Biological Life Sciences. |  Worldwide |
| Afatinib dimaleate | Afatinib (BIBW 2992) dimaleate is an orally active, potent and irreversible dual specificity inhibitor of ErbB family ( EGFR and HER2 ), with IC 50 values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFR wt , EGFR L858R , EGFR L858R/T790M and HER2, respectively. Afatinib dimaleate can be used for the research of esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC) and gastric cancer [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BIBW 2992MA2. CAS No. 850140-73-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10261A. | |
| Afatinib Impurity 2 | An analogue of Afatinib. Synonyms: 7-Quinazolinol, 4-[(3-chloro-4-fluorophenyl)?amino]?-6-nitro-. Grades: > 95%. CAS No. 1449430-45-8. Molecular formula: C14H8ClFN4O3. Mole weight: 334.7. | |
| Afatinib impurity 20 | Afatinib impurity 20. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1027929-81-2. Molecular formula: C8H4FN3O3. Mole weight: 209.14. Catalog: APB1027929812. |  |
| Afatinib Impurity 2F3Cl-1 | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: 4-Quinazolinamine, N-(3-chloro-2-fluorophenyl)-7-fluoro-6-nitro-. Grades: ≥95%. CAS No. 936558-43-9. Molecular formula: C14H7ClF2N4O2. Mole weight: 336.68. | |
| Afatinib Impurity 5 | An analogue of Afatinib. Synonyms: 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)?-7-methoxy-6-nitro-. Grades: > 95%. CAS No. 179552-74-0. Molecular formula: C15H10ClFN4O3. Mole weight: 348.72. | |
| Afatinib Impurity 52 | Afatinib Impurity 52 is an impurity of Afatinib, a drug used to treat non-small cell lung cancer (NSCLC). Synonyms: (S)-diethyl 2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamino)-2-oxoethylphosphonate; Diethyl {[4-(3-Chloro-4-Fluoro-Phenylamino)-7-((S)-Tetrahydrofuran-3-Yloxy)-Quinazolin-6-Ylcarbamoyl]-Methyl}-Phosphonate. Grades: 95%. CAS No. 618061-76-0. Molecular formula: C24H27ClFN4O6P. Mole weight: 552.92. | |
| Afatinib impurity 69 | Afatinib impurity 69. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-4-chloro-3-hydroxybutanoic acid. CAS No. 106941-19-9. Molecular formula: C4H7ClO3. Mole weight: 138.55. Catalog: APB106941199. | |
| Afatinib Impurity A | An analogue of Afatinib. Synonyms: 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)?-6-nitro-7-[[(3R)?-tetrahydro-3-furanyl]?oxy]?-. Grades: > 95%. CAS No. 402855-07-6. Molecular formula: C18H14ClFN4O4. Mole weight: 404.79. | |
| Afatinib Impurity AFT-8 | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: Afatinib Impurity QJJ; N-[4-((3-Chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)-3-hydroxybutenamide; Butanamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-3-hydroxy-. Grades: ≥95%. CAS No. 2323570-72-3. Molecular formula: C24H27ClFN5O4. Mole weight: 503.95. | |
| Afatinib Impurity B | An analogue of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: Afatinib-des(4-dimethylamino-2-en-1-oxo)butyl; N4-(3-Chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]-4,6-quinazolinediamine; (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine. Grades: > 95%. CAS No. 314771-76-1. Molecular formula: C18H16ClFN4O2. Mole weight: 374.81. | |
| Afatinib Impurity C | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)?amino]?-7-[[(3R)?-tetrahydro-3-furanyl]?oxy]?-6-quinazolinyl]?-4-(dimethylamino)?-, (2E)?-. Grades: > 95%. CAS No. 945553-91-3. Molecular formula: C24H25ClFN5O3. Mole weight: 485.95. | |
| Afatinib Impurity CSEJXA | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: (S)-N1-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-N2,N2-dimethyloxalamide (Afatinib Impurity; (S)-N1-(4-((3-CHLORO-4-FLUOROPHENYL)AMINO)-7-((TETRAHYDROFURAN-3-YL)OXY)QUINAZOLIN-6-YL)-N2,N2-DIMETHYLOXALAMIDE; Afatinib Impurity CSEJXA; CS-0164258; E82032; (S)-N1-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-N2,N2-dimethyloxalamide (Afatinib Impurity pound(c). Grades: ≥95%. CAS No. 2223677-66-3. Molecular formula: C22H21ClFN5O4. Mole weight: 473.88. | |
| Afatinib Impurity CSZ | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Grades: ≥95%. Molecular formula: C22H20ClFN4O5. Mole weight: 474.87. | |
| Afatinib impurity D | Afatinib impurity D. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S,Z)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide; Z-Afatinib. CAS No. 1680184-59-1. Molecular formula: C24H25ClFN5O3. Mole weight: 485.94. Catalog: APB1680184591. | |
| Afatinib Impurity D | An analogue of Afatinib, a medication indicated for the treatment of non-small cell lung carcinoma (NSCLC). Synonyms: (2Z)-Afatinib; Z-Afatinib; (S,Z)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide. Grades: > 95%. CAS No. 1680184-59-1. Molecular formula: C24H25ClFN5O3. Mole weight: 485.95. | |
| Afatinib Impurity ESS | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Grades: ≥95%. Molecular formula: C30H34ClFN6O4. Mole weight: 597.09. | |
| Afatinib Impurity I | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: Bromo-Afatinib; (S,E)-4-bromo-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide. Grades: ≥95%. CAS No. 1637254-93-3. Molecular formula: C22H19BrClFN4O3. Mole weight: 521.78. | |
| Afatinib Impurity J | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: (2E)-N-[3,4-Dihydro-4-oxo-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide; (S,E)-4-(DIMETHYLAMINO)-N-(4-HYDROXY-7-((TETRAHYDROFURAN-3-YL)OXY)QUINAZOLIN-6-YL)BUT-2-ENAMIDE; (S,e)-4-(dimethylamino)-N-(4-oxo-7-((tetrahydrofuran-3-yl)oxy)-3,4-dihydroquinazolin-6-yl)but-2-enamide; Afatinib Impurity J; SCHEMBL17352060; SCHEMBL17352063; GSUSIQVMAQBROU-PCAWENJQSA-N; CS-0164268; E82037; (S,E)-4-(Dimethylamino)-N-(4-hydroxy-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide (Afatinib Impurity). Grades: > 95%. CAS No. 1456696-14-2. Molecular formula: C18H22N4O4. Mole weight: 358.4. | |
| Afatinib Impurity JXH | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]formamide; Des(N,N-Dimethylprop-2-enyl-1-Amine) Afatinib. Grades: ≥95%. CAS No. 2223677-60-7. Molecular formula: C19H16ClFN4O3. Mole weight: 402.81. | |
| Afatinib Impurity N-Oxide | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: (S,E)-4-((4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)amino)-N,N-dimethyl-4-oxobut-2-en-1-amine oxide. Grades: ≥95%. CAS No. 2413212-11-8. Molecular formula: C24H25ClFN5O4. Mole weight: 501.94. | |
| Afatinib Impurity O | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: (S,E)-4-broMo-N-(4-((3-chloro-4-fluorophenyl)aMino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enaMide; (E)-4-bromo-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]but-2-enamide; Bromo-Afatinib; C22H19BrClFN4O3; AFATINIB IMPURITY O; SCHEMBL16398947; SCHEMBL16398952; IQJWAIKYBNTYPG-YUKKFKLSSA-N; CS-0164267; (2E)-4-Bromo-N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-2-butenamide; (S,E)-4-Bromo-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide (Afatinib Impurity). Grades: ≥95%. Molecular formula: C18H15FN4O4. Mole weight: 370.34. | |
| Afatinib Impurity Q | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Grades: ≥95%. Molecular formula: C14H7ClF2N4O2. Mole weight: 336.68. | |
| Afatinib Impurity QA | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Grades: ≥95%. Molecular formula: C18H16ClFN4O3. Mole weight: 390.80. | |
| Afatinib Impurity SCl | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: (S,E)-N-(4-((3,4-Dichlorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide. Grades: ≥95%. CAS No. 2223677-63-0. Molecular formula: C24H25Cl2N5O3. Mole weight: 502.39. | |
| Afatinib Impurity SM2A | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: 2-Butenamide, 4-(dimethylamino)-N,N-dimethyl-. Grades: ≥95%. CAS No. 1862246-17-0. Molecular formula: C8H16N2O. Mole weight: 156.23. | |
| Afatinib Impurity WZYGNH2 | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Grades: ≥95%. Molecular formula: C18H16ClFN4O2. Mole weight: 370.80. | |
| Afatinib Impurity WZYGNO2 | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Grades: ≥95%. Molecular formula: C18H14ClFN4O4. Mole weight: 404.78. | |
| (2Z)-Afatinib | (2Z)-Afatinib is a structural analogue of Afatinib (A355300), an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder. Group: Biochemicals. Grades: Highly Purified. CAS No. 1680184-59-1. Pack Sizes: 500ug, 1mg. Molecular Formula: C24H25ClFN5O3. US Biological Life Sciences. | Worldwide |
| (2Z)-Afatinib-d6 | (2Z)-Afatinib-d6 is the labeled analogue of (2Z)-Afatinib (A355305), a structural analogue of Afatinib (A355300), an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C24H19D6ClFN5O3, Molecular Weight: 491.98. US Biological Life Sciences. | Worldwide |
| 4-Chloro-3-fluoro Afatinib | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Grades: ≥95%. CAS No. 2406199-31-1. Molecular formula: C24H25ClFN5O3. Mole weight: 485.94. | |
| Des(dimethylamino)-Afatinib | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-2-butenamide; Afatinib Impurity H. Grades: ≥95%. CAS No. 2223677-64-1. Molecular formula: C22H20ClFN4O3. Mole weight: 442.87. | |
| 1-(4-((3-chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-5-hydroxypyrrolidin-2-one | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: Des-(4-dimethylamino-2-en-1-oxo)butylamino 6-(5-Hydroxy-pyrrolidin-2-on-1-yl) Afatinib; 2-Pyrrolidinone, 1-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-5-hydroxy-. Grades: ≥95%. CAS No. 2223677-58-3. Molecular formula: C22H20ClFN4O4. Mole weight: 458.87. | |
| (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide | (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide. Group: Biochemicals. Alternative Names: Afatinib; BIBW 2992. Grades: Highly Purified. CAS No. 439081-18-2,850140-72-6. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C24H25ClFN5O3. US Biological Life Sciences. | Worldwide |
| (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-fluoro-6-quinazolinyl]-4-(dimethylamino)-2-butenamide | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: Afatinib Impurity C. Grades: ≥95%. CAS No. 2170273-17-1. Molecular formula: C20H18ClF2N5O. Mole weight: 417.84. | |
| 3- ( (4- ( (3-Chloro-4-fluorophenyl) amino) -7- ( ( (S) -tetrahydrofuran-3-yl) oxy) quinazolin-6-yl) amino) -4- (dimethylamino) butanoic Acid | 3- ( (4- ( (3-Chloro-4-fluorophenyl) amino) -7- ( ( (S) -tetrahydrofuran-3-yl) oxy) quinazolin-6-yl) amino) -4- (dimethylamino) butanoic Acid is an intermediate in the synthesis of analogues of Afatinib (A355300). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg, 100mg. Molecular Formula: C24H27ClFN5O4. US Biological Life Sciences. | Worldwide |
| 3-Dimethylamino-1-propyne | 3-Dimethylamino-1-propyne is used as a reactant in the synthesis of quinazoline derivatives such as (2Z)-Afatinib (A355305) which may be used in the treatment of some cancers. Group: Biochemicals. Grades: Highly Purified. CAS No. 7223-38-3. Pack Sizes: 1g, 5g. Molecular Formula: C5H9N, Molecular Weight: 83.13. US Biological Life Sciences. | Worldwide |
| 4-N-(3-Chloro-4-fluorophenyl)-7-[(3R)-oxolan-3-yl]oxyquinazoline-4,6-diamine | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: (R)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diamine; (R)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine. CAS No. 402855-03-2. Molecular formula: C18H16ClFN4O2. Mole weight: 374.8. | |
| Becotatug | Becotatug (JMT-101) is an IgG1 antibody targeting EGFR that can also be conjugated to Afatinib (HY-10261) and Osimertinib (HY-15772) as a synthetic ADC [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: JMT-101. CAS No. 2648260-93-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990049. | |
| (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-hydroxyquinazolin-6-yl)-4-(dimethylamino)but-2-enamide | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: Afatinib Impurity L. Grades: ≥95%. CAS No. 2223677-61-8. Molecular formula: C20H19ClFN5O2. Mole weight: 415.85. | |
| N-(3-Chloro-4-fluorophenyl)-7-ethoxy-6-nitro-4-quinazolinamine | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: Afatinib Impurity YYJX. Grades: ≥95%. CAS No. 1360430-70-1. Molecular formula: C16H12ClFN4O3. Mole weight: 362.74. | |
| N4-(3-Chloro-4-Fluorophenyl)-7-Ethoxyquinazoline-4,6-Diamine | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: Afatinib Impurity YYJA. Grades: ≥95%. CAS No. 1269662-90-9. Molecular formula: C16H14ClFN4O. Mole weight: 332.76. | |
| N4-(3-Chloro-4-Fluorophenyl)-7-Methoxyquinazoline-4,6-Diamine | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-aminoquinazolin-4-amine; 4,6-Quinazolinediamine, N4-(3-chloro-4-fluorophenyl)-7-methoxy-; Afatinib Impurity JYJ-2. Grades: ≥95%. CAS No. 179552-75-1. Molecular formula: C15H12ClFN4O. Mole weight: 318.73. | |
| (S,E)-4-(dimethylamino)-N-(4-((4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: Afatinib Impurity 18. Grades: ≥95%. CAS No. 2413212-25-4. Molecular formula: C24H26FN5O3. Mole weight: 451.50. | |
| (S,E)-N-(4-((3,4-Difluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: 4-(Dimethylamino)but-2-enamide, (S,E)-N-(4-((3,4-difluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-; Afatinib Difluoro Analog; Afatinib Impurity SF. Grades: ≥95%. CAS No. 2223677-62-9. Molecular formula: C24H25F2N5O3. Mole weight: 469.48. | |
| (S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(methylamino)but-2-enamide | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(methylamino)-, (2E)-; Afatinib Impurity YJA. Grades: ≥95%. CAS No. 2413212-13-0. Molecular formula: C23H23ClFN5O3. Mole weight: 471.91. | |
| (S)-N4-(4-Fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: 4,6-Quinazolinediamine, N4-(4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]; Afatinib Impurity P. Grades: ≥95%. CAS No. 2413212-07-2. Molecular formula: C18H17FN4O2. Mole weight: 340.35. | |
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