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Aflatoxin B1-[13C17] is the labelled analogue of Aflatoxin B1, which is an aflatoxin produced by Aspergillus flavus and A. parasiticus. Synonyms: Aflatoxin B1-13C17. Grade: 95% atom 13C. CAS No. 1217449-45-0. Molecular formula: [13C]17H12O6. Mole weight: 329.15.
Aflatoxin B1 aldehyde reductase member 2 from Human, Recombinant
Aflatoxin B1 aldehyde reductase member 2 catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Has NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). Can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro). Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen. Group: Enzymes. Synonyms: AFB1 aldehyde reductase 1; AFB1-AR 1; Aldoketoreductase 7; Succinic semialdehyde reductase. Enzyme Commission Number: EC 1.1.1.n11. AKR7A2. Mole weight: 39588.9 Da. Source: Human. AFB1 aldehyde reductase 1; AFB1-AR 1; Aldoketoreductase 7; Succinic semialdehyde reductase; EC 1.1.1.n11; AKR7A2; Aflatoxin B1 aldehyde reductase member 2. Cat No: NATE-1196.
9-Dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B1
9-Dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B1 is the major DNA adduct formed by the liver carcinogen aflatoxin B1. Synonyms: 2-Amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-6,9-dihydro-7-(1,2,3,6a,8,9,9a,11-octahydro-9-hydroxy-4-methoxy-1,11-dioxocyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-8-yl)-6-oxo-1H-purinium; AFB1-N7-Gua; Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran, 1H-purinium deriv. CAS No. 64585-66-6. Molecular formula: C27H26N5O11. Mole weight: 596.52.
3'-AdG, a DNA adduct of aflatoxin B1, a potent carcinogen, represents an essential biomarker for exposure to the mentioned carcinogen. Furthermore, it is a critical tool for studying the complex connection between aflatoxin B1 and liver cancer. With its unparalleled sensitivity and specificity, 3'-AdG offers the perfect platform for insightful analysis of this highly debated topic. Synonyms: 3'- Amino- 3'- deoxyguanosine. Grade: ≥ 98% by HPLC. CAS No. 80015-76-5. Molecular formula: C10H14N6O4. Mole weight: 282.3.
Isotope labelled 4-Methoxy-2-methyl-2, 3-dihydrocyclopenta [c]furo [3', 2': 4, 5]furo [2, 3-h]chromene-1, 11 (6aH, 9aH) -dione-d6 is an intermediate in the synthesis of Aflatoxin B1 (A357460), a group of very carcinogenic mycotoxins with hepatoxic effects. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250ug. US Biological Life Sciences.
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AFB-Guanine-13C,15N2
A labelled guanine adduct of Aflatoxin B1. Synonyms: (6aS,8R,9R,9aR)-8-(2-Amino-1,6-dihydro-6-oxo-7H-purin-7-yl)-2,3,6a,8,9,9a-hexahydro-9-hydroxy-4-methoxy-cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione-13C,15N2. Molecular formula: C21[13C]H17N3[15N]2O8. Mole weight: 482.38.
AFB-Guanine Acetic Acid Salt
Acetic acid of a guanine adduct of Aflatoxin B1. Synonyms: (6aS,8R,9R,9aR)-8-(2-Amino-1,6-dihydro-6-oxo-7H-purin-7-yl)-2,3,6a,8,9,9a-hexahydro-9-hydroxy-4-methoxy-cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione Acetic Acid. Grade: 95%. Molecular formula: C24H21N5O10. Mole weight: 539.45.
Aflatoxicol
Aflatoxin (Aflatoxin R0) is a metabolite of aflatoxin B1 produced from Rhizopus spp [1] , and is mutagenic and carcinogenic mycotoxin [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Aflatoxin R0. CAS No. 29611-03-8. Pack Sizes: 1 mg. Product ID: HY-N6695.
Aflatoxin B2
Aflatoxins B1, B2, G1, G2 as secondary metabolites of fungal species such as Aspergillus flavus or Aspergillus parasiticus growing on a variety of foods (peanuts, nuts, spices, cereals). Aflatoxins are a group of very carcinogenic mycotoxins with hepatotoxic effects. Group: Biochemicals. Alternative Names: (6aR, 9aS) -2, 3, 6a, 8, 9, 9a-Hexahydro-4-methoxycyclopenta [c]furo [3, 2: 4, 5]furo [2, 3-h] [1]benzopyran-1, 11-dione; Dihydroaflatoxin B1; Dihydroaflatoxine B1. Grades: Highly Purified. CAS No. 7220-81-7. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences.
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Aflatoxin B2-[13C17]
Aflatoxin B2-[13C17] is the labelled analogue of Aflatoxin B2, which is a mycotoxin found in A. terricola. Synonyms: Aflatoxin B2-13C17; (3S,7R)-11-methoxy-6,8,19-trioxapentacyclo[10.7.0.02,9.03,7.013,17]nonadeca-1,9,11,13(17)-tetraene-16,18-dione-13C17; Dihydroaflatoxine B1-13C17; 2,3,6aR,8,9,9aS-hexahydro-4-methoxy-cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione-13C17; Fully 13C-labelled Aflatoxin B2. Grade: ≥95%. CAS No. 1217470-98-8. Molecular formula: [13C]17H14O6. Mole weight: 331.16.
Aflatoxin G2
Aflatoxins B1, B2, G1, G2 as secondary metabolites of fungal species such as Aspergillus flavus or Aspergillus parasiticus growing on a variety of foods (peanuts, nuts, spices, cereals). Aflatoxins are a group of very carcinogenic mycotoxins with hepatotoxic effects. Group: Biochemicals. Alternative Names: (7aR, 10aS)-3, 4, 7a, 9, 10, 10a-Hexahydro-5-methoxy-1H, 12H-furo[3', 2':4, 5]furo[2, 3-h]pyrano[3, 4-c][1]benzopyran-1, 12-dione. Grades: Highly Purified. CAS No. 7241-98-7. Pack Sizes: 1mg. US Biological Life Sciences.
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Aflatoxin M1
An Aspergillus flavus metabolite. Aflatoxin M1 in milk as a secondary metabolite of the Aflatoxin B1 formed in moldy forages. It is cancerogenic, hepatotoxic, and immunosuppressive in animals and man. Group: Biochemicals. Alternative Names: (6aR, 9aR)-2, 3, 6a, 9a-Tetrahydro-9a-hydroxy-4-methoxy-cyclopenta[c]furo[3, 2:4, 5]furo[2, 3-h][1]benzopyran-1, 11-dione; AFM1. Grades: Highly Purified. CAS No. 6795-23-9. Pack Sizes: 250ug. US Biological Life Sciences.
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Aflatoxin M1
It is produced by the strain of Aspergillus flavus, Asp. parasiticus. The compound of aflatoxin has the activity of anti-gram-positive bacteria, inhibits cell mitosis, has the effect of liver necrosis and carcinogenesis, and is a mycotoxin which contaminates food. Synonyms: AFLATOXIN M1; 4-Hydroxyaflatoxin B1; 3020O28I3; CCRIS 15; (6aR,9aR)-9a-hydroxy-4-methoxy-2,3,6a,9a-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11-dione; (6aR-cis)-2,3,6a,9a-tetrahydro-9a-hydroxy-4-methoxycyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione; CHEBI:78576; Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione,2,3,6a,9a-tetrahydro-9a-hydroxy-4-methoxy-,(6ar,9ar)-. Grade: ≥95%. CAS No. 6795-23-9. Molecular formula: C17H12O7. Mole weight: 328.27.
Aflatoxin Q1
Aflatoxin Q1 is a metabolite of Aflatoxin B1. It is created in human body as a in-vivo detoxification process of Aflatoxin B1. Uses: A metabolite of aflatoxin b1; a hepatocarcinogen in many animal models and probably a human carcinogen. it is produced by the predominant forms of cytochrome p 450 enzymes responsible for the biotransformation of afb1. it shows potential predictive value. Synonyms: Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-3-hydroxy-4-methoxy-, (3S,6aR,9aS)-; Cyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-3-hydroxy-4-methoxy-, (3S-(3-alpha,6a-alpha,9a-alpha))-; (3S,6aR,9aS)-3-hydroxy-4-methoxy-2,3,6a,9a-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11-dione. Grade: ≥98%. CAS No. 52819-96-2. Molecular formula: C17H12O7. Mole weight: 328.27.
Averantin
Averantin is an anthraquinone fungal metabolite produced by Aspergillus sp. associated with Panax notoginseng. It is a mycotoxic intermediate in the pathway to aflatoxin B1. It displays antifungal activity against Fusariumsolani (pathogenic fungus of P. notoginseng) with minimum inhibitory concentrations of 16-32 ug/mL. It also shows antibacterial activity against Bacillus subtilis with minimum inhibitory concentrations of 16-32 ug/mL. Synonyms: 1,3,6,8-Tetrahydroxy-2-[(1S)-1-hydroxyhexyl]-9,10-anthracenedione; (-)-Averantin; (S)-1,3,6,8-Tetrahydroxy-2-(1-hydroxyhexyl)-9,10-anthracenedione; 9,10-Anthracenedione, 1,3,6,8-tetrahydroxy-2-[(1S)-1-hydroxyhexyl]-; (1'S)-averantin; (S)-(-)-averantin; (S)-averantin. Grade: ≥95%. CAS No. 5803-62-3. Molecular formula: C20H20O7. Mole weight: 372.37.
Mycotoxin. Intermediate of the biosynthetic pathway to aflatoxin B1. Cytotoxic against human solid tumor cell lines. Group: Biochemicals. Grades: Highly Purified. CAS No. 5803-62-3. Pack Sizes: 1mg, 5mg. US Biological Life Sciences.
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Standard Solution Aflatoxin Mixture
The acetonitrile solution of 0.5 ppm for each of four mixed Aflatoxin species: Aflatoxin B1, Aflatoxin B2, Aflatoxin G1 and Aflatoxin G2, could be commonly used as a standard solution.
Sterigmatocystin (NSC 201423, NSC 204985)
Intermediate of the biosynthetic pathway to aflatoxin B1. Mycotoxin. DNA synthesis inhibitor. Anticancer compound. Cytotoxic, carcinogenic and mutagenic. Acyl-CoA:cholesterol acyltransferase 2 (ACAT2) inhibitor. Shown to induce apoptosis in human peripheral lymphocytes and necrosis in rat liver. Induces sister chromatid exchanges in murine bone marrow cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 10048-13-2. Pack Sizes: 1mg, 5mg. US Biological Life Sciences.
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