Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| AG 490 | AG 490. Group: Biochemicals. Grades: Purified. CAS No. 133550-30-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| AG 490 - CAS 133550-30-8 | A cell-permeable, reversible, substrate competitive, and potent inhibitor of epidermal growth factor receptor kinase autophosphorylation (IC?? = 100 nM). Group: Fluorescence/luminescence spectroscopy. |  |
| AG 490, m-CF? - CAS 581797-29-7 | A cell-permeable, reversible, substrate competitive, m-trifluoromethyl derivative of AG 490 that displays apoptotic and antiproliferative properties. Group: Fluorescence/luminescence spectroscopy. | |
| AG 490 (Tyrphostin B42, N-benzyl-3, 4-dihydroxy-benzylidene cyanoacetamide) | Specific and potent JAK2 protein tyrosine kinase inhibitor. Also, inhibits EGF receptor autophosphorylation, with IC50 of 100nM. Inhibits DNA synthesis and cell growth; induces apoptosis. Blocks growth of leukemic cells in vitro and in vivo. Group: Biochemicals. Alternative Names: Tyrphostin B42. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| AG-490 | Tyrphostin AG490 is a JAK-2 specific inhibitor, which inhibits phosphorylation of EGFR and signal transducer and activator of transcription 3 [STAT-3], and subsequently reduce invasion and adhesion potential of malignant cells. Uses: Antineoplastic agents. Synonyms: Tyrphostin AG 490; AG-490; AG490. Grade: 0.98. CAS No. 133550-30-8. Molecular formula: C17H14N2O3. Mole weight: 294.31. |  |
| Tyrphostin AG 490 | solid. Group: Fluorescence/luminescence spectroscopy. | |
| (11 β , ?16α ) ?-9-?Fluoro-?11-?hydroxy-?17, ?21-?[ (1-?methoxypentylidene) ?bis (oxy) ?]?-?16-?methyl-pregna-?1, ?4-?diene-?3, ?20-?dione | (11 β , ?16α ) ?-9-?Fluoro-?11-?hydroxy-?17, ?21-?[ (1-?methoxypentylidene) ?bis (oxy) ?]?-?16-?methyl-pregna-?1, ?4-?diene-?3, ?20-?dione is an intermediate in synthesizing Dexamethasone Valerate (D298870), an impurity of Dexamethasone (D298800), which is a glucocorticoid that is used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase. Group: Biochemicals. Grades: Highly Purified. CAS No. 1062-64-2. Pack Sizes: 25mg, 50mg. Molecular Formula: C28H39FO6, Molecular Weight: 490.6. US Biological Life Sciences. | Worldwide |
| 1-Methoxy-4-nitronaphthalene | 1-Methoxy-4-nitronaphthalene is used as a reagent in the synthesis of UMI-77 (U700850); a small molecule inhibitor of Mcl-1 which blocks and attenuates pancreatic cell cancer growth. Also an anticancer agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 4900-63-4. Pack Sizes: 500mg, 1g. Molecular Formula: C11H9NO3, Molecular Weight: 203.19. US Biological Life Sciences. | Worldwide |
| 2-Bromo-5-methyl-4-nitropyridine | 2-Bromo-5-methyl-4-nitropyridine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-BROMO-5-METHYL-4-NITROPYRIDINE, 66092-62-4, AGN-PC-00MI1W, CTK5C3503, MolPort-020-000-063, ANW-44635, 2-bromanyl-5-methyl-4-nitro-pyridine, AKOS015966431, AG-G-49008, PB26621, Pyridine, 2-bromo-5-methyl-4-nitro-, AK-64558, KB-229020, C-8741, A835332. Product Category: Heterocyclic Organic Compound. CAS No. 66092-62-4. Molecular formula: C6H5BrN2O2. Mole weight: 217.020100 [g/mol]. Purity: 0.96. IUPACName: 2-bromo-5-methyl-4-nitropyridine. Density: 1.709g/cm³. Product ID: ACM66092624. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 3,4-O-Isopropylidene-1,2-di-O-methyl-6-O-trityl-a-D-galactopyranoside | 3,4-O-Isopropylidene-1,2-di-O-methyl-6-O-trityl-α-D-galactopyranoside, a widely utilized compound in the biomedical industry, finds its place as a fundamental component in research endeavors. Renowned for its distinct chemical structure, it fuels the synthesis of innovative pharmaceutical agents targeting a wide array of specific diseases and disorders. Within the realm of biomedicine, its applications extend to encompass cancer, viral infections, and metabolic anomalies. Synonyms: Methyl 3,4-O-Isopropylidene-2-O-methyl-6-O-trityl-alpha-D-galactopyranoside; Methyl 3,4-O-Isopropylidene-2-O-methyl-6-O-trityl-?-D-galactopyranoside; (3aS,4R,6S,7R,7aS)-6,7-dimethoxy-2,2-dimethyl-4-(trityloxymethyl)-4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyran. CAS No. 69182-49-6. Molecular formula: C30H34O6. Mole weight: 490.60. | |
| 3,5,6-Tri-O-benzyl-1,2-O-Isopropylidene-a-D-glucofuranose | 3,5,6-Tri-O-benzyl-1,2-O-Isopropylidene-a-D-glucofuranose is an invaluable compound extensively employed in the biomedical sector. This compound assumes a pivotal function in the synthesis of glycosides and glycoconjugates, thus facilitating drug development and disease management. Remarkably, it serves as a fundamental component in the formulation and exploration of innovative therapeutic agents aimed at combating diverse ailments such as cancer, bacterial infections, and viral ailments. Synonyms: 3,5,6-Tri-O-benzyl-1,2-O-isopropylidene-alpha-D-glucofuranose. CAS No. 53928-30-6. Molecular formula: C30H34O6. Mole weight: 490.59. | |
| 3,6-Difluoro-2-(trifluoromethyl)pyridine | 3,6-Difluoro-2-(trifluoromethyl)pyridine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3,6-Difluoro-2-(trifluoromethyl)pyridine, 1099597-92-8, CTK7B9620, ZINC30714852, AKOS005255234, 3,6-Difluoro-2-trifluoromethylpyridine, AG-A-49026, FT-0678626, I02-4747. Product Category: Heterocyclic Organic Compound. CAS No. 1099597-92-8. Molecular formula: C6H2F5N. Mole weight: 183.08. Purity: 0.96. IUPACName: 3,6-difluoro-2-(trifluoromethyl)pyridine. Canonical SMILES: C1=CC(=NC(=C1F)C(F)(F)F)F. Product ID: ACM1099597928. Alfa Chemistry ISO 9001:2015 Certified. | |
| 4-Chloro-5-(1-methylhydrazino)-2-(4-methylphenyl)-2,3-dihydropyridazin-3-one | 4-Chloro-5-(1-methylhydrazino)-2-(4-methylphenyl)-2,3-dihydropyridazin-3-one. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 41933-01-1, 4-chloro-5-(1-methylhydrazino)-2-(4-methylphenyl)-2,3-dihydropyridazin-3-one, ZINC00153216, AC1MCP3S, SureCN11732577, CTK4I5438, AG-F-49050, OR21715, KB-190832, 5-[amino(methyl)amino]-4-chloro-2-(4-methylphenyl)pyridazin-3-one, 3(2H)-Pyridazinone,4-chloro-5-(1-methylhydrazinyl)-2-(4-methylphenyl)-, 4-chloro-5-(1-methylhydrazin-1-yl)-2-(4-methylphenyl)pyridazin-3-one, 3(2H)-Pyridazinone,4-chloro-5-(1-methylhydrazino)-2-(4-methylphenyl)- (9CI). Product Category: Heterocyclic Organic Compound. CAS No. 41933-01-1. Molecular formula: C12H13ClN4O. Mole weight: 264.71. Purity: 0.96. IUPACName: 5-[amino(methyl)amino]-4-chloro-2-(4-methylphenyl)pyridazin-3-one. Canonical SMILES: CC1=CC=C(C=C1)N2C(=O)C(=C(C=N2)N(C)N)Cl. Density: 1.34g/cm³. Product ID: ACM41933011. Alfa Chemistry ISO 9001:2015 Certified. | |
| Adenanthin | Adenanthin can induce differentiation of acute promyelocytic leukemia (APL) cells, which is isolated from the leaves of Rabdosia adenantha, it also can serve as what is to our knowledge the first lead natural compound for the development of Prx I -and Prx II - targeted therapeutic agents, which may represent a promising approach to inducing differentiation of APL cells. Uses: Anti-inflammatory, anti-tumour, anti-leukemic. Synonyms: Actinodephnine Acuminatin Acuminatoside Adenanthin. Grade: >98%. CAS No. 111917-59-0. Molecular formula: C26H34O9. Mole weight: 490.6. | |
| ADPM06 | ADPM06 is a nonporphyrin photodynamic therapeutic (PDT) agent, which is an established treatment modality for cancer. It exhibits IC50s in the micro-molar range in human tumor cells and induces apoptosis. Synonyms: ADPM-06; ADPM 06; Azadipyrromethane. CAS No. 490035-90-0. Molecular formula: C34H24BBr2F2N3O2. Mole weight: 715.2. | |
| Apyramide | Apyramide is a non-steroidal anti-inflammatory agent (NSAID) that is a prodrug of indomethacin. Indomethacin is a potent, blood-brain permeable, non-selective inhibitor of COX1 and COX2. Synonyms: 4-(Acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate; 1-(p-Chlorobenzoyl)-2-methyl-5-methoxyindole-3-p-acetamidophenol acetate; 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid 4-(acetylamino)phenyl ester; 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 4-(acetylamino)phenyl ester. Grade: ≥95%. CAS No. 68483-33-0. Molecular formula: C27H23ClN2O5. Mole weight: 490.93. | |
| β-Tocotrienol | β-Tocotrienol is isolated from the stem bark of Garcinia virgata. It inhibits the growth of both A549 (GI50=1.38±0.334μM) and U87MG (GI50=2.53±0.604μM) cells at rather low concentrations. β-Tocotrienol can serve as a new anticancer agent for treating human lung and brain cancers. Synonyms: (2R)-3,4-Dihydro-2,5,8-trimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrien-1-yl]-2H-1-benzopyran-6-ol; 2,5,8-Trimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-6-chromanol; D-β-Tocotrienol; ε-Tocopherol; ε-Tokoferol. Grade: 97.5%. CAS No. 490-23-3. Molecular formula: C28H42O2. Mole weight: 410.63. | |
| Clopidogrel Impurity D | Clopidogrel Carboxylic Acid [Methyl (R)-o-chloromandelate] Ester is an impurity of Clopidogrel, an antithrombotic agent. Synonyms: Clopidogrel Carboxylic Acid [Methyl (R)-o-chloromandelate] Ester. Grade: > 95%. CAS No. 1421283-60-4. Molecular formula: C24H21Cl2NO4S. Mole weight: 490.4. | |
| Cycloastragenol | Cycloastragenol, belongs to the triterpene saponins, is mainly obtained from the hydrolysis of Astragaloside IV. Cycloastradiol is the only telomerase activator found today. It delays the shortening of telomeres by increasing telomerase. Cycloastradiol is believed to have anti-aging effects. Cycloastragenol can be used in cosmetics material. Synonyms: 9,19-Cyclolanostane-3,6,16,25-tetrol, 20,24-epoxy-, (3β,6α,16β,20R,24S)-; (3β,6α,16β,20R,24S)-20,24-Epoxy-9,19-cyclolanostane-3,6,16,25-tetrol; Astramembrangenin; Cyclosieversigenin; Cyclosiversigenin; Cyloastragenol; (2aR,3R,4S,5aS,5bS,7S,7aR,9S,11aR,12aS)-3-((2R,5S)-5-(2-hydroxypropan-2-yl)-2-methyltetrahydrofuran-2-yl)-2a,5a,8,8-tetramethyltetradecahydro-1H,12H-cyclopenta[a]cyclopropa[e]phenanthrene-4,7,9-triol. Grade: 98%. CAS No. 78574-94-4. Molecular formula: C30H50O5. Mole weight: 490.72. | |
| Dexamethasone 21-tert-Butylacetate | Dexamethasone 21-tert-Butylacetate is a derivative of Dexamethasone, which is a glucocorticoid used as an anti-inflammatory agent. Synonyms: Dexamethasone tebutate; (11β,16α)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl 3,3-dimethylbutanoate; Butanoic acid, 3,3-dimethyl-, (11β,16α)-9-fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl ester; Dexamethasone tert-Butylacetate. Grade: ≥95%. CAS No. 24668-75-5. Molecular formula: C28H39FO6. Mole weight: 490.60. | |
| Dilithium disodium 4,4'-bis[(4-hydroxyphenyl)azo]stilbene-2,2'-disulfonate | Dilithium disodium 4,4'-bis[(4-hydroxyphenyl)azo]stilbene-2,2'-disulfonate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CTK5C3531, AG-G-49092, DILITHIUM DISODIUM 4,4-BIS[(4-HYDROXYPHENYL)AZO]STILBENE-2,2-DISULPHONATE, 66104-72-1. Product Category: Heterocyclic Organic Compound. CAS No. 66104-72-1. Molecular formula: C52H36Li2N8Na2O16S4. Mole weight: 1217.007779 [g/mol]. Purity: 0.96. IUPACName: dilithium;disodium;5-[2-(4-oxocyclohexa-2,5-dien-1-ylidene)hydrazinyl]-2-[2-[4-[2-(4-oxocyclohexa-2,5-dien-1-ylidene)hydrazinyl]-2-sulfonatophenyl]ethenyl]benzenesulfonate. Canonical SMILES: [Li+].[Li+].C1=CC(=O)C=CC1=NNC2=CC(=C(C=C2)C=CC3=C(C=C(C=C3)NN=C4C=CC(=O)C=C4)S(=O)(=O)[O-])S(=O)(=O)[O-].C1=CC(=O)C=CC1=NNC2=CC(=C(C=C2)C=CC3=C(C=C(C=C3)NN=C4C=CC(=O)C=C4)S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+].[Na+]. ECNumber: 266-159-5. Product ID: ACM66104721. Alfa Chemistry ISO 9001:2015 Certified. | |
| EC-17 disodium salt | EC-17 disodium salt is a folate receptor alpha (FR?) targeting contrast agent with fluorescent properties in the visible light spectrum. The EC-17 maximum excitation and emission wavelengths are 490 nm and 520 nm, respectively[1][2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 910661-33-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13615A. |  |
| Edasalonexent | Edasalonexent, also known as CAT-1004, is a NF-kappa B inhibitor under the development of Catabasis Pharmaceuticals and Sarepta Therapeutics. It is a Inflammation mediator inhibitor and could be an anti-inflammatory drug candidate. In Apr 2016, Phase-II clinical trials in Duchenne muscular dystrophy (In children) in USA were on-going. In Sep 2016, Catabasis Pharmaceuticals and Sarepta Therapeutics agreed to co-develop edasalonexent with an exon skipping treatment together in USA for Duchenne muscular dystrophy. Uses: Anti-inflammatory; duchenne muscular dystrophy. Synonyms: CAT-1004; CAT1004; CAT 1004; Edasalonexent; Sodium salicylate-docosahexaenoic acid conjugate; N-(2-((4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenamido)ethyl)-2-hydroxybenzamide. Grade: 98%. CAS No. 1204317-86-1. Molecular formula: C31H42N2O3. Mole weight: 490.69. | |
| (-)-Epicatechin | Potent antioxidant and antineoplastic agent. Group: Biochemicals. Alternative Names: (2R,3R)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol; epi-Catechin; epi-Catechol; l-Acacatechin; l-Epicatechin; l-Epicatechol. Grades: Highly Purified. CAS No. 490-46-0. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Homoquinolinic acid | Homoquinolinic acid is a potent NMDA receptor agonist and neurotoxic agent. Synonyms: 3-Pyridineacetic acid, 2-carboxy-; 2-carboxy-3-Pyridineacetic acid; Homoquinolinate; 3-(carboxymethyl)pyridine-2-carboxylic acid. Grade: ≥99% by HPLC. CAS No. 490-75-5. Molecular formula: C8H7NO4. Mole weight: 181.15. | |
| Homoquinolinic Acid (3-Carboxymethylpyridine-2-carboxylic Acid, 3-Pyridineacetic Acid, 2-carboxy-Homoquinolinate) | A potent agonist fornMDA receptor with subunit-selectivity of NR2A/B (EC50 = 26uM) over NR2C (EC50 = 60uM). Used as a potent neurotoxic agent and for identifying endogenous receptors containing the NR2C subunit. Group: Biochemicals. Grades: Highly Purified. CAS No. 490-75-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| JAK Inhibitor I (P6, DBI, (2-(1,1-Dimethylethyl)-9-fluoro-3,6-dihydro-7H-benz[h]-imidaz[4,5-f]isoquinolin-7-one, Pyridone 6, JAK1 Inhibitor I, JAK3 Inhibitor VII, JAK2 Inhibitor I) | A potent, reversible, cell-permeable, and ATP-competitive inhibitor of Janus protein tyrosine kinases (JAKs). Displays potent inhibitory activity against JAK1 (IC50=15nM for murine JAK1), JAK2 (IC50=1nM), JAK3 (Ki=5nM), and Tyk2 (IC50=1nM). Inhibits other kinases at much higher concentrations. Shown to inhibit IL2- and IL4-dependent proliferation of CTLL cells and block the phosphorylation of STAT5; and further induce growth inhibition of multiple myeloma cells expressing activated JAKs and STAT3, unlike AG 490. A 10mM solution of JAK Inhibitor I in DMSO is also available. Group: Biochemicals. Grades: Highly Purified. CAS No. 457081-03-7. Pack Sizes: 500ug, 1mg. US Biological Life Sciences. | Worldwide |
| Kresoxim-methyl | An agricultural fungicide. Group: Biochemicals. Alternative Names: (α E) -α - (methoxyimino) -2-[ (2-methylphenoxy) methyl]benzeneacetic acid methyl ester; BAS 490-02F; BAS 490F; Candit; Cygnus; Discus; Discus (fungicide); RIL-FA 200; Strob 1; Stroby; Stroby WG. Grades: Highly Purified. CAS No. 143390-89-0. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea | N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 330796-24-2, AG-F-11158, N-[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]-N-[[3-(4-FLUOROPHENYL)-3,4-DIHYDRO -4-OXO-2-QUINAZOLINYL]METHYL]UREA, N-[4-Chloro-3-(trifluoromethyl)phenyl]-N-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea, SureCN1483882, CHEMBL270928, CTK4G9897, ZINC20272111, AKOS015891430, KB-10992, FT-0664996, I01-9533, N-[4-Chloro-3-(trifluoromethyl)phenyl]-NAA inverted exclamation markAA -[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea, Urea,N-[4-chloro-3-(trifluoromethyl)phenyl]-N-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]-. Product Category: Heterocyclic Organic Compound. CAS No. 330796-24-2. Molecular formula: C23H15ClF4N4O2. Mole weight: 490.84. Purity: 0.96. IUPACName: 1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[[3-(4-fluorophenyl)-4-oxoquinazolin-2-yl]methyl]urea. Canonical SMILES: C1=CC=C2C(=C1)C(=O)N(C(=N2)CNC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)C4=CC=C(C=C4)F. Density: 1.469g/cm³. Product ID: ACM330796242. Alfa Chemistry ISO 9001:2015 Certified. | |
| Pyridostatin hydrochloride | Pyridostatin (RR82) hydrochloride is a G-quadruplex DNA stabilizing agent (Kd=490 nM) and can target DNA and RNA G4s in cells. Pyridostatin hydrochloride promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin hydrochloride targets the proto-oncogene Src. Pyridostatin hydrochloride reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RR82 hydrochloride. CAS No. 1781882-65-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15176A. | |
| SODIUM CARBONATE-13C | SODIUM CARBONATE-13C. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Sodium carbonate-13C, 93673-48-4, 490768_ALDRICH, CTK8G3145, AG-H-82730. Product Category: Heterocyclic Organic Compound. CAS No. 93673-48-4. Molecular formula: CNa2O3. Mole weight: 107. Purity: 0.96. IUPACName: disodium;oxomethanediolate. Canonical SMILES: C(=O)([O-])[O-].[Na+].[Na+]. Product ID: ACM93673484. Alfa Chemistry ISO 9001:2015 Certified. | |
| Tetraheptylammonium bromide | Tetraheptylammonium bromide is a quaternary ammonium compound (QAC) mainly used as a phase-transfer agent. Uses: Tetraheptylammonium bromide is a catalyst in organic polymer synthesis involving redox-active crystals of polymetalate. reagent used in the preparation of ionic liquids as novel quartz collectors. Group: Electrolytesbattery materials. Alternative Names: Tetra-n-heptylammoniumbromide. CAS No. 4368-51-8. Product ID: tetraheptylazanium; bromide. Molecular formula: 490.69. Mole weight: C28H60BrN. CCCCCCC[N+] (CCCCCCC) (CCCCCCC)CCCCCCC. [Br-]. InChI=1S/C28H60N. BrH/c1-5-9-13-17-21-25-29 (26-22-18-14-10-6-2, 27-23-19-15-11-7-3) 28-24-20-16-12-8-4; /h5-28H2, 1-4H3; 1H/q+1; /p-1. YQIVQBMEBZGFBY-UHFFFAOYSA-M. ≥99%. |  |
| Triptolide | Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii. It has immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is an NF-κB activation inhibitor. Uses: Adcs cytotoxin. Synonyms: NSC 163062; PG490; Trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-, (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-; (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-3b,4,4a,6,6a,7a,7b,8b,9,10-Decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one; (-)-Triptolide; PG 490; Triptolide. Grade: >98%. CAS No. 38748-32-2. Molecular formula: C20H24O6. Mole weight: 360.40. | |
| WP1066 ((2E)-3-(6-Bromo-2-pyridinyl)-2-cyano-N-[(1S)-1-phenylethy]-2-propenamide) | A potent, cell-permeable JAK2 inhibitor. A novel analog of the JAK2 inhibitor AG490 that blocks STAT3 and phosphoinositide-3-kinase pathways. It is significantly more potent and active against human malignant glioma cells in vitro and in vivo than AG 490. Similar to AG490, WP1066 inhibits the phosphorylation of JAK2, but unlike AG490, WP1066 also degrades JAK2 protein, thus blocking its downstream signal transducer and activator of transcription (STAT) and phosphoinositide-3-kinase pathways to results in the activation of the caspase pathway. Group: Biochemicals. Grades: Purified. CAS No. 857064-38-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| (Z)-Guggulsterone | Z-Guggulsterone is a broad spectrum steroid receptor ligand that acts as a mineralocorticoid, progesterone and glucocorticoid receptor antagonist (Ki = 37, 224 and 252 nM, respectively) and weak androgen receptor agonist (Ki = 315 nM). Z-Guggulsterone is also a selective antagonist of farnesoid X receptor (FXR) exhibiting antilipidemic, antiseptic, antirheumatic and anti-inflammatory activity in vivo. Synonyms: (Z)-Guggulsterone; Z-Guggulsterone; Guggulsterone; 39025-23-5; 95975-55-6; Guggulsterones Z; Cis-Guggulsterone; Guggulsterone E&Z; GUGGULSTERONE Z; Guggulsterone, (Z)-; Z/E-Guggulsterone; (Z)-Pregna-4,17(20)-diene-3,16-dione; 6CST3U34GN; DTXSID1033539; Pregna-4,17(20)-diene-3,16-dione, (17Z)-; Pregna-4,17(20)-diene-3,16-dione; (8R,9S,10R,13S,14S,17Z)-17-ethylidene-10,13-dimethyl-1,2,6,7,8,9,11,12. Grade: ≥98% by HPLC. CAS No. 39025-23-5. Molecular formula: C28H22N6O3. Mole weight: 490.5. | |
Our database is helping our users find suppliers everyday.
