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| Product | Description | |
|---|---|---|
| Aldosterone | 25mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C21H28O5. CAS No. 52-39-1. Prepack ID 12239606-25mg. Molecular Weight 360.44. See USA prepack pricing. |  |
| Aldosterone | Aldosterone is the primary mineralocorticoid. Aldosterone is a steroid hormone, and it is synthesized and secreted in response to renin-angiotensin system activation (RAS) or high dietary potassium by the zona glomerulosa (ZG) of the adrenal cortex. Aldosterone activity is dependent by the binding and activation of the cytoplasmic/nuclear mineralocorticoid receptor (MR) at cellular level [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 52-39-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-113313. |  |
| Aldosterone | An adrenocortical steroid which exerts regulatory influence on metabolism of electrolytes and water. Biologically active aldosterone isomer; a mineralocorticoid produced by the adrenal cortex that induces urinary excretion of K+ and renal reabsorptioon of Na+. Exists as an equilibrium mixture of the aldehyde and the hemiacetal. Group: Biochemicals. Alternative Names: 4-Pregnen-11β, 21-Diol-3, 18, 20-Trione; (11 β)-11,21-Dihydroxy-3,20-dioxopregn-4-en-18-al; 11 β,21-Dihydroxypregn-4-ene-3,18,20-trione; 18-Formyl-11 β,21-dihydroxy-4-pregnene-3,20-dione; 18-Oxocorticosterone; Aldocorten; Aldocortene; Aldocortin; Electrocortin; Elektrocortin; NSC 73856; Reichstein X. Grades: Highly Purified. CAS No. 52-39-1. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C??H??O?, Molecular Weight: 360.44. US Biological Life Sciences. |  Worldwide |
| Aldosterone | An adrenocortical steroid which exerts regulatory influence on metabolism of electrolytes and water. Synonyms: (11β)-11,21-Dihydroxy-3,20-dioxopregn-4-en-18-al; 11β,21-Dihydroxypregn-4-ene-3,18,20-trione; 18-Formyl-11β,21-dihydroxy-4-pregnene-3,20-dione; 18-Oxocorticosterone; Electrocortin; Aldocortin; Aldocorten. Grades: > 95%. CAS No. 52-39-1. Molecular formula: C21H28O5. Mole weight: 360.45. |  |
| Aldosterone 18-Oxime 21-Acetate | Used in the preparation of Aldosterone, an adrenocortical steroid which exerts regulatory influence on metabolism of electrolytes and water. Group: Biochemicals. Alternative Names: Aldosterone Oxime 21-Acetate; (11 β)-21-(Acetyloxy)-11-hydroxy-3,20-dioxo-pregn-4-en-18-al 18-Oxime. Grades: Highly Purified. CAS No. 74220-49-8. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Aldosterone 21-Acetate | Aldosterone derivative. Group: Biochemicals. Alternative Names: Aldosterone 21-Monoacetate; (11 β)-21-(Acetyloxy)-11,18-epoxy-18-hydroxy-pregn-4-ene-3,20-dione. Grades: Highly Purified. CAS No. 2827-21-6. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Aldosterone-d7 (Major) | A labeled adrenocortical steroid which exerts regulatory influence on metabolism of electrolytes and water. Biologically active aldosterone isomer; a mineralocorticoid produced by the adrenal cortex that induces urinary excretion of K+ and renal reabsorptioon of Na+. Exists as an equilibrium mixture of the aldehyde and the hemiacetal. Group: Biochemicals. Alternative Names: (11 β)-11,21-Dihydroxy-3,20-dioxopregn-4-en-18-al-d7; 11 β,21-Dihydroxypregn-4-ene-3,18,20-trione-d7; 18-Formyl-11 β,21-dihydroxy-4-pregnene-3,20-dione-d7; 18-Oxocorticosterone-d7; Aldocortene-d7; Electrocortin-d7; Elektrocortin-d7; NSC 73856-d7; Reichstein X-d7. Grades: Highly Purified. Pack Sizes: 25ug. US Biological Life Sciences. | Worldwide |
| Aldosterone secretion inhibiting factor(1-35)(bovine) | Heterocyclic Organic Compound. Alternative Names: ALDOSTERONE SECRETION INHIBITING FACTOR (1-35) (BOVINE);ALDOSTERONE SECRETION INHIBITORY FACTOR (1-35) (BOVINE);H-ALA-LEU-ARG-GLY-PRO-LYS-MET-MET-ARG-ASP-SER-GLY-CYS-PHE-GLY-ARG-ARG-LEU-ASP-ARG-ILE-GLY-SER-LEU-SER-GLY-LEU-GLY-CYS-ASN-VAL-LEU-ARG-ARG-TYR-. CAS No. 120249-06-1. Molecular formula: C164H278N58O45S4. Mole weight: 3910.58. Catalog: ACM120249061. |  |
| 1-Dehydroaldosterone | A metabolite of Aldosterone. Synonyms: (11β)-11,21-Dihydroxy-3,20-dioxopregna-1,4-dien-18-al; Δ1-Aldosterone; 11β,21-Dihydroxy-3,20-dioxopregna-1,4-dien-18-al; 1-Dehydroaldosterone. Grades: > 95%. CAS No. 76959-24-5. Molecular formula: C21H26O5. Mole weight: 358.44. | |
| Tetrahydro Aldosterone | A metabolite of Aldosterone. Synonyms: (3α,5β,11β)-11,18-Epoxy-3,18,21-trihydroxypregnan-20-one; 11β,18-Epoxy-3α,18,21-Τrihydroxy-5β-pregnan-20-one; 3α,5β-Tetrahydro- aldosterone; Tetrahydroaldosterone. Grades: > 95%. CAS No. 13489-75-3. Molecular formula: C21H32O5. Mole weight: 364.49. | |
| 11-Deoxy-18-hydroxycorticosterone | 11-Deoxy-18-hydroxycorticosterone is an analog of Corticosterone (C695700); a glucocorticoid and intermediate in the biosynthesis of Aldosterone (A514700) which is an adrenocortical steroid isolated from the adrenal cortex. Group: Biochemicals. Grades: Highly Purified. CAS No. 379-68-0. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C21H30O4, Molecular Weight: 346.46. US Biological Life Sciences. | Worldwide |
| 11-Deoxy Corticosterone | A mineralocorticoid that occurs in adrenal cortex. It acts as a precursor to Aldosterone. Group: Biochemicals. Grades: Highly Purified. CAS No. 64-85-7. Pack Sizes: 10mg, 50mg, 100mg, 500mg. Molecular Formula: C??H??O?. US Biological Life Sciences. | Worldwide |
| 11-Deoxy Corticosterone-d7 | Labelled Deoxycorticosterone. A mineralocorticoid that occurs in adrenal cortex. It acts as a precursor to Aldosterone (A514700). Group: Biochemicals. Alternative Names: 21-Hydroxypregn-4-ene-3,20-dione-d7; 11-Deoxycorticosterone-d7; 11-Dehydroxy-corticosterone-d7; 11-Desoxycorticosterone-d7; 21-Hydroxy-3,20-dioxopregn-4-ene-d7; 21-Hydroxy-4-pregnane-3,20-dione-d7. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 11-Deoxy Corticosterone-d8 | Labeled Deoxycorticosterone. A mineralocorticoid that occurs in adrenal cortex. It acts as a precursor to Aldosterone. Group: Biochemicals. Alternative Names: 21-Hydroxypregn-4-ene-3,20-dione-d8; 11-Deoxycorticosterone-d8; 11-Dehydroxy-corticosterone-d8; 11-Desoxycorticosterone-d8; 21-Hydroxy-3,20-dioxopregn-4-ene-d8; 21-Hydroxy-4-pregnane-3,20-dione-d8. Grades: Highly Purified. CAS No. 55487-63-3. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 16-Hydroxycorticosterone 20-Hydroxy-21-Acid (Mixture of Diastereomers) | 16-Hydroxycorticosterone 20-Hydroxy-21-Acid is an oxidized derivative of corticosterone (007040), an intermediate in the biosynthesis of aldosterone (001762), isolated from the adrenal cortex. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| (17α)-17-Hydroxy-3-oxo-pregna-4,6,20-triene-21-carboxylic Acid γ-Lactone | (17α)-17-Hydroxy-3-oxo-pregna-4,6,20-triene-21-carboxylic Acid γ-Lactone is an intermediate in synthesizing 20,21-Dehydro Spironolactone (D229405), which is an impurity of Spironolactone (S683000), a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conns syndrome. Group: Biochemicals. Grades: Highly Purified. CAS No. 52845-58-6. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C22H26O3. US Biological Life Sciences. | Worldwide |
| (17α)-7-Cyano-17-hydroxy-3-oxo-pregna-4,9(11)-diene-21-carboxylic acid γ-Lactone | Used in the preparation of 17-spirosteroids as aldosterone receptor antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 1197900-95-0. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 17α-Ethoxymethyl 6-Dehydrotestosterone | 17α-Ethoxymethy 6-Dehydrotestosterone is an intermediate in the synthesis of 7 β-Acetylthio-17α-ethoxymethy Testosterone which is an impurity of Spironolactone (S683000), which is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conns syndrome. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C22H32O3. US Biological Life Sciences. | Worldwide |
| 17α-Ethynyltestosterone Acryl Ester | 17α-Ethynyltestosterone Acryl Ester is an intermediate in synthesizing 20,21-Dehydro Spironolactone (D229405), which is an impurity of Spironolactone (S683000), a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conns syndrome. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C24H30O3. US Biological Life Sciences. | Worldwide |
| 17α-Vinyltestosterone Acryl Ester | 17α-Vinyltestosterone Acryl Ester is an intermediate in synthesizing 20,21-Dehydro Spironolactone (D229405), which is an impurity of Spironolactone (S683000), a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conns syndrome. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C24H32O3. US Biological Life Sciences. | Worldwide |
| 17 β-Spiro[5-androsten-17,2'-oxiran]-3 β-ol | 17 β-Spiro[5-androsten-17,2'-oxiran]-3 β-ol is an intermediate in the synthesis of 7 β-Acetylthio-17α-ethoxymethy Testosterone which is an impurity of Spironolactone (S683000), which is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conns syndrome. Group: Biochemicals. Grades: Highly Purified. CAS No. 847-75-6. Pack Sizes: 25mg, 50mg. Molecular Formula: C20H30O2. US Biological Life Sciences. | Worldwide |
| 17-Deoxycortolone | 17-Deoxycortolone, is a metabolite of Corticosterone (C695700), an intermediate in the biosynthesis of aldosterone, isolated from the adrenal cortex. Group: Biochemicals. Grades: Highly Purified. CAS No. 600-68-0. Pack Sizes: 1mg. Molecular Formula: C21H34O4, Molecular Weight: 350.49. US Biological Life Sciences. | Worldwide |
| 17-(Ethoxymethyl) Androst-5-ene-3 β,17 β-diol | 17-(Ethoxymethyl) Androst-6-ene-3 β,17 β-diol is an intermediate in the synthesis of 7 β-Acetylthio-17α-ethoxymethy Testosterone which is an impurity of Spironolactone (S683000), which is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conns syndrome. Group: Biochemicals. Grades: Highly Purified. CAS No. 855-49-2. Pack Sizes: 10mg, 25mg. Molecular Formula: C22H36O3. US Biological Life Sciences. | Worldwide |
| 17-Hydroxy-3-oxo-17α-pregna-4,20-diene-21-carboxylic Acid γ-Lactone | 17-Hydroxy-3-oxo-17α-pregna-4,20-diene-21-carboxylic Acid γ-Lactone is an intermediate in synthesizing 20,21-Dehydro Spironolactone (D229405), which is an impurity of Spironolactone (S683000), a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conns syndrome. Group: Biochemicals. Grades: Highly Purified. CAS No. 52845-59-7. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C22H28O3. US Biological Life Sciences. | Worldwide |
| 17-Hydroxypregn-5-ene-3,20-dione | 17-Hydroxypregn-5-ene-3,20-dione is used in the synthesis of physiologically active steroid esters and spirolactones that functions as potential aldosterone antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 641-80-5. Pack Sizes: 10mg, 25mg. Molecular Formula: C21H30O3. US Biological Life Sciences. | Worldwide |
| 18-Oxocortisol | 18-Oxocortisol is a derivative of cortisol that is produced by aldosterone synthase (CYP11B2). 18-Oxocortisol is a naturally occurring mineralocorticoid agonist. 18-Oxocortisol is a biomarker in adrenal vein sampling [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 2410-60-8. Pack Sizes: 500 μg; 1 mg. Product ID: HY-113151. | |
| 1-Cycloocten-1-ol 1-Acetate | 1-Cycloocten-1-ol 1-Acetate is a derivative of cyclooctanone (C988345), a aliphatic cycle that exhibited inhibitory activity towards aldosterone synthase, a promising therapeutic target for the treatment of cardiovascular diseases related to abnormally high aldosterone level. Group: Biochemicals. Alternative Names: 1-Cycloocten-1-ol Acetate; 1-Acetoxycyclooctene; 1-Cycloocten-1-yl Acetate; 1-Cyclooctenyl Acetate. Grades: Highly Purified. CAS No. 14478-13-8. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 20,21-Dehydro Spironolactone | 20,21-Dehydro Spironolactone (Spironolactone EP Impurity A) is an impurity of Spironolactone (S683000), a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conns syndrome. Group: Biochemicals. Grades: Highly Purified. CAS No. 132458-33-4. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C24H30O4S. US Biological Life Sciences. | Worldwide |
| 21 β-Hydroxyeplerenone | 21 β-Hydroxyeplerenone is a derivative of the parent compound Eplerenone (E588775), which is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure. Group: Biochemicals. Grades: Highly Purified. CAS No. 1633889-97-0. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C24H30O7. US Biological Life Sciences. | Worldwide |
| 21-(Cyclohex-1-enyl)pregn-4-ene-3,20-dione | 21-(Cyclohex-1-enyl)pregn-4-ene-3,20-dione, is a derivative of deoxycorticosterone (D232590), a mineralocorticoid that occurs naturally in the adrenal cortex. It acts as a precursor to Aldosterone (A514700). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C27H38O2, Molecular Weight: 394.59. US Biological Life Sciences. | Worldwide |
| 21-Hydroxy Eplerenone | A metabolite of Eplerenone. Eplerenone is a potassium-sparing diuretic that selectively blocks aldosterone activation of the mineralcorticoid receptor, demonstrating little activity towards other steroid receptors. Synonyms: (7α,11α,17α)-9,11-epoxy-17, 21-hydroxy- -3-oxo-pregn-4-ene-7,21-dicarboxylic acid, γ-lactone, 7-methyl ester. Grades: > 95%. Molecular formula: C24H30O7. Mole weight: 430.50. | |
| 21-Hydroxyeplerenone (α, β mixture) | 21-Hydroxyeplerenone is a metabolite of Eplerenone (E588775), which is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure. 21-Hydroxyeplerenone is a metabolite of eplerenone in humans and dogs. Group: Biochemicals. Grades: Highly Purified. CAS No. 334678-67-0. Pack Sizes: 500ug, 1mg. Molecular Formula: C24H30O7. US Biological Life Sciences. | Worldwide |
| 3-(1H-Imidazol-1-ylmethyl)aniline | 3-(1H-Imidazol-1-ylmethyl)aniline functions as a selective aldosterone synthase inhibitors. Research on antibacterial and antifungal agents (benzenamine derivatives). Group: Biochemicals. Grades: Highly Purified. CAS No. 120107-85-9. Pack Sizes: 100mg, 250mg. Molecular Formula: C10H11N3, Molecular Weight: 173.21. US Biological Life Sciences. | Worldwide |
| 3 β,5-Dihydroxy-15 β,16 β-methylene-5 β-androst-6-en-17-one | An impurity of the synthetic progestogen Drospirenone. It is used in the preparation of aldosterone antagonists. Group: Biochemicals. Alternative Names: (3 β,5 β, 15α, 16α)-15, 16-Dihydro-3, 5-dihydroxy-3'H-cycloprop[15, 16]androsta-6, 15-dien-17-one; 15 β,16 β-Methylene-3 β,5 β-dihydroxyandrost-6-en-17-one. Grades: Highly Purified. CAS No. 82543-15-5. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 3-Bromo-1,2-dihydroacenapthylene | 3-Bromo-1,2-dihydroacenapthylene is an aldosterone synthase (CYP11B2) inhibitor for the treatment of congestive heart failure and myocardial fibrosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 5209-31-4. Pack Sizes: 10mg, 25mg. Molecular Formula: C12H9Br, Molecular Weight: 233.1. US Biological Life Sciences. | Worldwide |
| 6β-Hydroxy Eplerenone | A metabolite of Eplerenone. Eplerenone is a potassium-sparing diuretic that selectively blocks aldosterone activation of the mineralcorticoid receptor, demonstrating little activity towards other steroid receptors. Synonyms: (6β, 7α, 11α, 17α)-9, 11-Epoxy-6, 17-dihydroxy-3-oxo-pregn-4-ene-7, 21-dicarboxylic Acid γ-Lactone Methyl Ester. Grades: > 95%. CAS No. 209253-80-5. Molecular formula: C24H30O7. Mole weight: 430.50. | |
| Anacetrapib | Anacetrapib (MK0859) is a potent, selective, reversible rhCETP and mutant CETP(C13S) inhibitor with IC50 of 7.9 nM and 11.8 nM, increases HDL-C and decreases LDL-C, does not increase aldosterone or blood pressure. Synonyms: MK-0859; MK 0859; MK0859; Anacetrapib. Grades: 0.99. CAS No. 875446-37-0. Molecular formula: C30H25F10NO3. Mole weight: 637.518. | |
| Angiotensin Acetate | Angiotensin acetate is an angiotensin II analog that is an agonist at angiotensin receptors. It is an oligopeptide and is a hormone and a powerful dipsogen. It is derived from the precursor molecule angiotensinogen, a serum globulin produced in the liver. It is a peptide hormone that causes vasoconstriction and a subsequent increase in blood pressure. It is part of the renin-angiotensin system, which is a major target for drugs that lower blood pressure. It plays an important role in the renin-angiotensin system. It also stimulates the release of aldosterone, another hormone, from the adrenal cortex. Uses: Angiotensin acetate causes vasoconstriction and a subsequent increase in blood pressure. it plays an important role in the renin-angiotensin system. Synonyms: ASP-ARG-VAL-TYR-VAL-HIS-PRO-PHE;H-ASP-ARG-VAL-TYR-VAL-HIS-PRO-PHE-OH;Angiotensin II 5-valine;Valine angiotensin II;5-L-Valine angiotensin II. Grades: 98%. CAS No. 58-49-1. Molecular formula: C49H69N13O12. Mole weight: 1032.15. | |
| Baxdrostat | Baxdrostat is a aldosterone synthase inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CIN-107. CAS No. 1428652-17-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132809. | |
| Baxdrostat | Baxdrostat is an aldosterone synthase inhibitor. Synonyms: N-[(8R)-4-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-5,6,7,8-tetrahydroisoquinolin-8-yl]propanamide; (R)-N-(4-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-5,6,7,8-tetrahydroisoquinolin-8-yl)propionamide; N-[(8R)-4-(1-Methyl-2-oxo-1,2,3,4-tetrahydro-6-quinolinyl)-5,6,7,8-tetrahydro-8-isoquinolinyl]propanamide; Propanamide, N-[(8R)-5,6,7,8-tetrahydro-4-(1,2,3,4-tetrahydro-1-methyl-2-oxo-6-quinolinyl)-8-isoquinolinyl]-. CAS No. 1428652-17-8. Molecular formula: C22H25N3O2. Mole weight: 363.45. | |
| Brain natriuretic peptide (1-32) (human) | An agonist at atrial natriuretic peptide (ANP) receptor A (NRP1) which is secreted from cardiac ventricles in response to volume increase and pressure overload. It exhibits natriuretic, vasodilatory and lusitropic activity and suppresses sympathetic and renin-angiotensin-aldosterone systems in vivo, and decreases de novo collagen synthesis as well as increases MMP gene expression in vitro. Synonyms: Brain Natriuretic Peptide-32 human; BNP-32 (human); Nesiritide; H-Ser-Pro-Lys-Met-Val-Gln-Gly-Ser-Gly-Cys(1)-Phe-Gly-Arg-Lys-Met-Asp-Arg-Ile-Ser-Ser-Ser-Ser-Gly-Leu-Gly-Cys(1)-Lys-Val-Leu-Arg-Arg-His-OH; L-seryl-L-prolyl-L-lysyl-L-methionyl-L-valyl-L-glutaminyl-glycyl-L-seryl-glycyl-L-cysteinyl-L-phenylalanyl-glycyl-L-arginyl-L-lysyl-L-methionyl-L-alpha-aspartyl-L-arginyl-L-isoleucyl-L-seryl-L-seryl-L-seryl-L-seryl-glycyl-L-leucyl-glycyl-L-cysteinyl-L-lysyl-L-valyl-L-leucyl-L-arginyl-L-arginyl-L-histidine (10->26)-disulfide. Grades: ≥99% by HPLC. CAS No. 124584-08-3. Molecular formula: C143H244N50O42S4. Mole weight: 3464.04. | |
| Canrenoate potassium | Canrenoate (Aldadiene) potassium, a proagent that releases canrenone, is a potent, competitive mineralocorticoid receptor (aldosterone receptor) antagonist. Potassium canrenoate, as a diuretic, is used for the research of hypertension [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Aldadiene potassium; SC-14266. CAS No. 2181-4-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1582A. | |
| Canrenoic Acid Potassium Salt | Canrenoic acid is an aldosterone antagonist. Canrenoic acid is used as an diuretic. Group: Biochemicals. Alternative Names: (17α)-17-Hydroxy-3-oxopregna-4,6-diene-21-carboxylic Acid Potassium Salt; Aldadiene Kalium; Aldadiene Potassium; CB 8109; Canrenoate Potassium; Kanrenol; MF 465 a; Potassium 17-Hydroxy-3-oxo-17α-pregna-4,6-diene-21-carboxylate; Potassium 3-(17 β-Hydroxy-3-oxoandrosta-4,6-dien-17-yl)propionate; Potassium 3-(3-oxo-17 β-hydroxy-4,6-androstadien-17α-yl)propionate; Potassium Aldadiene; Potassium Canrenoate; Potassium β-(3-Oxo-17 β-hydroxyandrosta-4,6-dien-17α-yl)Propionate; SC 14266; SC 14266/371; Soldactona; Soldactone; Soludactone; Venactone. Grades: Highly Purified. CAS No. 2181-04-6. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| Canrenone | Canrenone (Aldadiene) is an aldosterone antagonist extensively used as a diuretic agent. Uses: Scientific research. Group: Natural products. Alternative Names: Aldadiene; SC9376. CAS No. 976-71-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1438. | |
| Canrenone ((7a)-17-Hydroxy-3-oxo-pregna-4,6-diene-21-carboxylic Acid g-Lactone; 17a-(2-Carboxyethyl-17b-hydroxyandrosta-4,6-dien-3-one Lactone, Phanurane) | Aldosterone antagonist. Diuretic. Group: Biochemicals. Alternative Names: (7a)-17-Hydroxy-3-oxo-pregna-4,6-diene-21-carboxylic Acid g-Lactone; 17a-(2-Carboxyethyl-17b-hydroxyandrosta-4,6-dien-3-one Lactone; Phanurane. Grades: Highly Purified. CAS No. 976-71-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Canrenone-d6 (Major) | Labeled Aldosterone antagonist. Diuretic. Group: Biochemicals. Alternative Names: (7α)-17-Hydroxy-3-oxo-pregna-4,6-diene-21-carboxylic Acid γ-Lactone-d6; 17α-2-Carboxyethyl-17 β-hydroxyandrosta-4,6-dien-3-one Lactone-d6; Phanurane-d6. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Canrenone (Standard) | Canrenone (Standard) is the analytical standard of Canrenone. This product is intended for research and analytical applications. Canrenone (Aldadiene) is an aldosterone antagonist extensively used as a diuretic agent. Uses: Scientific research. Group: Natural products. Alternative Names: Aldadiene(Standard); SC9376 (Standard). CAS No. 976-71-6. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1438R. | |
| Cenderitide | Cenderitide is a potent agonist of particulate guanylyl cyclase receptor (pGC). Cenderitide is a natriuretic peptide (NP) composed of C-type natriuretic peptide (CNP) fused to the C-terminus of Dendroaspis natriuretic peptide (DNP). Cenderitide activates both pGC-A and pGC-B , activates the second messenger cGMP , suppresses aldosterone , and preserves GFR without reducing blood pressure. Cenderitide can be used for heart failure research [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 507289-11-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3624. | |
| Corticosterone 21-Acetate | Corticosterone derivative. An intermediate in the biosynthesis of aldosterone, isolated from the adrenal cortex. Group: Biochemicals. Alternative Names: Cort A; NSC 81764; SKF 5654; (11 β)-21-(Acetyloxy)-11-hydroxy-pregn-4-ene-3,20-dione. Grades: Highly Purified. CAS No. 1173-26-8. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Corticosterone-d8 (Major) | Labeled Corticosterone. Glucocorticoid; an intermediate in the biosynthesis of aldosterone, isolated from the adrenal cortex. Group: Biochemicals. Alternative Names: (11 β)-11,21-Dihydroxy-pregn-4-ene-3,20-dione-d8; 11,21-Dihydroxyprogesterone-d8; 17-Deoxycortisol-d8; 4-Pregnene-11 β,21-diol-3,20-dione-d8; Corticosteron-d8; Kendall's compound B-d8; NSC 9705-d8. Grades: Highly Purified. CAS No. 1271728-07-4. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Cyclooctanone | Cyclooctanone is a aliphatic cycle that exhibited inhibitory activity towards aldosterone synthase, a promising therapeutic target for the treatment of cardiovascular diseases related to abnormally high aldosterone level. Group: Biochemicals. Alternative Names: NSC 9475. Grades: Highly Purified. CAS No. 502-49-8. Pack Sizes: 25g. US Biological Life Sciences. | Worldwide |
| Δ4-3-oxosteroid 5β-reductase | The enzyme from human efficiently catalyses the reduction of progesterone, androstenedione, 17α-hydroxyprogesterone and testosterone to 5β-reduced metabolites; it can also act on aldosterone, corticosterone and cortisol, but to a lesser extent. The bile acid intermediates 7α,12α-dihydroxy-4-cholesten-3-one and 7α-hydroxy-4-cholesten-3-one can also act as substrates. Group: Enzymes. Synonyms: 3-oxo-Δ4-steroid 5β-reductase; 5β-reductase; androstenedione 5β-reductase; cholestenone 5β-reductase; cortis. Enzyme Commission Number: EC 1.3.1.3. CAS No. 9029-8-7. 3-oxo-5-beta-steroid 4-dehydrogenase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1303; Δ4-3-oxosteroid 5β-reductase; EC 1.3.1.3; 9029-08-7; 3-oxo-Δ4-steroid 5β-reductase; 5β-reductase; androstenedione 5β-reductase; cholestenone 5β-reductase; cortisone 5β-reductase; cortisone β-reductase; cortisone Δ4-5β-reductase; steroid 5β-reductase; testosterone 5β-reductase; Δ4-3-ketosteroid 5β-reductase; Δ4-5β-reductase; Δ4-hydrogenase; 4,5β-dihydrocortisone:NADP+ Δ4-oxidoreductase; 3-oxo-5β-steroid:NADP+ Δ4-oxidoreductase. Cat No: EXWM-1303. |  |
| Δ9-Canrenone | Intermediate in the preparation of steroidal aldosterone blockers. Group: Biochemicals. Alternative Names: 17 β-Hydroxy-4,6,9(11)-trien-3-one 21-carboxylic Acid γ-Lactone; Δ9-11-Canrenone. Grades: Highly Purified. CAS No. 95716-71-5. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Deoxycorticosterone | Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor. Deoxycorticosterone is an agonist for O. mykiss mineralocorticoid receptor ( rtMR ) transcription with EC 50 of 0.16 nM [3]. Deoxycorticosterone could acts as an immune stimulator in fish [4]. Uses: Scientific research. Group: Natural products. CAS No. 64-85-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-113414. | |
| Deoxycorticosterone acetate | Deoxycorticosterone acetate (DOCA) is an adrenocortin, acts as a precursor to aldosterone. Deoxycorticosterone acetate is a mineralocorticoid receptor agonist. Deoxycorticosterone acetate can cause severe renal injury, including inflammation, fibrosis, glomerular damage, and proteinuria [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 11-Deoxycorticosterone acetate; DOC acetate; Cortexone acetate. CAS No. 56-47-3. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1472. | |
| Deserpidine | Deserpidine is an antihypertensive drug related to Reserpine. It is naturally found in Rauvolfia spp. Deserpidine is a competitive ACE (angiotensin converting enzyme) inhibitor. Deserpidine can block the conversion of angiotensin I to angiotensin II as a potent vasoconstrictor through competing with angiotensin I for ACE. Reduced level of serum angiotensin II leads to a decrease in blood pressure. Deserpidine can also decrease angiotensin II-induced aldosterone secretion by the adrenal cortex. Uses: Antihypertensive drug. Synonyms: (3β, 16β, 17α, 18β, 20α)-17-methoxy-18-[(3, 4, 5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic Acid Methyl Ester; Deserpidic Acid Methyl Ester 3,4,5-Trimethoxybenzoate; Deserpidin; 1-Demethoxyreserpine; 11-Desmethoxyreserpine; Canescin; Canescine; Canescine (Rauwolfia); Harmonyl; NSC 72138; Raunormin; Raunormine; Recanescin; Recanescine; Reserpidine. Grades: 95%. CAS No. 131-01-1. Molecular formula: C32H38N2O8. Mole weight: 578.66. | |
| Dexfadrostat | Dexfadrostat ((R)-Fadrozole) is a potent nonsteroidal inhibitor [1]. Dexfadrostat also inhibits human placental aromatase (pIC 50 = 6.17) and aldosterone biosynthesis. Dexfadrostat reverses cardiac fibrosis in spontaneously hypertensive heart failure rats. [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-Fadrozole; (R)-CGS 16949A free base; FAD286. CAS No. 102676-87-9. Pack Sizes: 10 mM * 1 mL; 1 mg. Product ID: HY-113986. | |
| Enalkiren | Enalkiren: Introducing Enalkiren is an efficacious and exclusive suppressor of human renin, a pivotal enzyme within the renin-angiotensin-aldosterone system. Its indispensable role lies in studying hypertension (increased blood pressure) and congestive heart failure. Uses: Protease inhibitors. Synonyms: Enalquireno; Enalkirene; 3-amino-N-[(2S)-1-[[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-(4-methoxyphenyl)-1-oxopropan-2-yl]-3-methylbutanamide. CAS No. 113082-98-7. Molecular formula: C35H56N6O6. Mole weight: 656.86. | |
| Eplerenone | Eplerenone (Epoxymexrenone) is a selective, highly specific and orally active aldosterone blocker (SAB). Eplerenone also is a selective mineralocorticoid receptor antagonist (MRA) with IC 50 value of 0.081 μM. Eplerenone can be used for the research of hypertension, atherosclerosis, chronic systolic heart failure (HF) and cardiovascular (CV) [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Epoxymexrenone. CAS No. 107724-20-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0251. | |
| Eplerenone | Selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure. Group: Biochemicals. Alternative Names: (7α, 11α, 17α)-9, 11-Epoxy-17-hydroxy-3-oxopregn-4-ene-7, 21-dicarboxylic Acid; γ-Lactone 7-Methyl Ester; CGP 30083; Epoxymexrenone; Inspra; SC-66110. Grades: Highly Purified. CAS No. 107724-20-9. Pack Sizes: 250mg, 500mg, 1g, 5g. Molecular Formula: C??H??O?, Molecular Weight: 414.49. US Biological Life Sciences. | Worldwide |
| Eplerenone EP Impurity A | An impurity of Eplerenone. Eplerenone is a potassium-sparing diuretic that selectively blocks aldosterone activation of the mineralcorticoid receptor, demonstrating little activity towards other steroid receptors. Synonyms: (7α,17α)- 9,17-Dihydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Di-γ-lactone. Grades: > 95%. CAS No. 209253-67-8. Molecular formula: C23H28O5. Mole weight: 384.48. | |
| Eplerenone EP Impurity B | An impurity of Eplerenone. Eplerenone is a potassium-sparing diuretic that selectively blocks aldosterone activation of the mineralcorticoid receptor, demonstrating little activity towards other steroid receptors. Synonyms: (7α, 11α, 12α, 17α)-11, 12-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7, 21-dicarboxylic Acid Lactone, Methyl Ester. Grades: > 95%. CAS No. 192704-82-8. Molecular formula: C24H30O6. Mole weight: 414.50. | |
| Eplerenone EP Impurity C | An impurity of Eplerenone. Eplerenone is a potassium-sparing diuretic that selectively blocks aldosterone activation of the mineralcorticoid receptor, demonstrating little activity towards other steroid receptors. Synonyms: Δ9,11-7β-Eplerenone; (2'R,7R,8R,10S,13S,14S)-Methyl 10,13-dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,10,12,13,14,15,16-tetradecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-carboxylate; (7a,17a)-17-Hydroxy-3-oxo-pregna-4,9(11)-diene-7,21-dicarboxylic acid g-lactone methyl ester. Grades: > 95%. CAS No. 95716-70-4. Molecular formula: C24H30O5. Mole weight: 398.50. | |
| Eplerenone EP Impurity D | An impurity of Eplerenone. Eplerenone is a potassium-sparing diuretic that selectively blocks aldosterone activation of the mineralcorticoid receptor, demonstrating little activity towards other steroid receptors. Synonyms: Eplerenone 7-Carboxylic Acid; 9,11-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid γ-Lactone. Grades: > 95%. CAS No. 209253-82-7. Molecular formula: C23H28O6. Mole weight: 400.48. | |
| Eplerenone EP Impurity E | An impurity of Eplerenone. Eplerenone is a potassium-sparing diuretic that selectively blocks aldosterone activation of the mineralcorticoid receptor, demonstrating little activity towards other steroid receptors. Synonyms: 7β-Eplerenone; (7β,11α,17α)-9,11-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid γ-Lactone Methyl Ester. Grades: > 95%. CAS No. 209253-81-6. Molecular formula: C24H30O6. Mole weight: 414.50. | |
| Eplerenone EP Impurity F Potassium Salt | An impurity of Eplerenone. Eplerenone is a potassium-sparing diuretic that selectively blocks aldosterone activation of the mineralcorticoid receptor, demonstrating little activity towards other steroid receptors. Synonyms: (7α,11α,17α)-9,11-Epoxy-17-hydroxy-3-oxopregn-4-ene-7,21-dicarboxylic Acid; 7-Methyl Ester Monopotassium Salt; SC 70303; Eplerenone EP Impurity F Potassium Salt. Grades: > 95%. CAS No. 95716-98-6. Molecular formula: C24H31O7K. Mole weight: 470.6. | |
| Eplerenone EP Impurity G | An impurity of Eplerenone. Eplerenone is a potassium-sparing diuretic that selectively blocks aldosterone activation of the mineralcorticoid receptor, demonstrating little activity towards other steroid receptors. Synonyms: Mexrenone; Spiro[17H-cyclopenta[a]phenanthrene-17,2'(5'H)-furan], pregn-4-ene-7,21-dicarboxylic acid deriv.; 17-Hydroxy-3-oxo-17α-pregn-4-ene-7α,21-dicarboxylic acid methyl ester γ-lactone. Grades: > 95%. CAS No. 41020-65-9. Molecular formula: C24H32O5. Mole weight: 400.52. | |
| Eplerenone Impurity 1 | An impurity of Eplerenone. Eplerenone is a potassium-sparing diuretic that selectively blocks aldosterone activation of the mineralcorticoid receptor, demonstrating little activity towards other steroid receptors. Synonyms: (2'R,7S,10R,11R,13S,14S)-methyl 11-hydroxy-10, 13-dimethyl-3, 5'-dioxo-1, 2, 3, 4', 5', 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16-hexadecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17, 2'-furan]-7-carboxylate. Grades: > 95%. Molecular formula: C24H32O6. Mole weight: 416.52. | |
| Forasartan | Forasartan, a tetrazol derivative, has been found to be a angiotensin II receptor antagonist that could be effective against hypertension through influencing the vasoconstriction and the formation of aldosterone. Uses: Forasartan has been found to be a angiotensin ii receptor antagonist that could be effective against hypertension through influencing the vasoconstriction and the formation of aldosterone. Synonyms: Forasartan; SC-52458; SC 52458; SC52458. UNII-065F7WPT0B; CHEMBL315021; 5-[(3,5-dibutyl-1,2,4-triazol-1-yl)methyl]-2-[2-(2H-tetrazol-5-yl)phenyl]pyridine. Grades: 98%. CAS No. 145216-43-9. Molecular formula: C23H28N8. Mole weight: 416.52. | |
| Lorundrostat | Lorundrostat (MT-4129) is an orally active aldosterone synthase inhibitor. Lorundrostat can be used in studies of high blood pressure [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MT-4129. CAS No. 1820940-17-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147277. | |
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