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(2E)-5-Hydroxy-2-pentenoic Acid Methyl Ester is an intermediate in the preparation of unusual amino acids that are potential Michael acceptor based antiplasmodial and antitrypanosomal cysteine protease inhibitors. Group: Biochemicals. Alternative Names: (E)-5-Hydroxy-2-pentenoic Acid Methyl Ester. Grades: Highly Purified. CAS No. 62592-80-7. Pack Sizes: 50mg. US Biological Life Sciences.
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3-Methyl Glutaconyl CoA (mixture of regioisomers)
3-Methylglutaconyl CoA is an intermediate produced by dehydration of 3-Hydroxy-3-methylglutaconyl CoA during the production of Isovaleryl CoA metabolite by myxobacteria. Synonyms: Mixture of S-(5-Hydrogen 3-Methyl-2-pentenedioate) Coenzyme A and S-(5-Hydrogen 3-Methyl-3-pentenedioate) Coenzyme A; Mixture of (E) -5- ( (2- (3- ( (2R) -4- ( ( ( ( ( ( (2R, 3S, 4R, 5R) -5- (6-amino-9H-purin-9-yl) -4-hydroxy-3- (phosphonooxy) tetrahydrofuran-2-yl) methoxy) (hydroxy) phosphoryl) oxy) (hydroxy) phosphoryl) oxy) -2-hydroxy-3, 3-dimethylbutanamido) propanamido) ethyl) thio) -3-methyl-5-oxopent-3-enoic Acid and (E) -5- ( (2- (3- ( (2R) -4- ( ( ( ( ( ( (2R, 3S, 4R, 5R) -5- (6-amino-9H-purin-9-yl) -4-hydroxy-3- (phosphonooxy) tetrahydrofuran-2-yl) methoxy) (hydroxy) phosphoryl) oxy) (hydroxy) phosphoryl) oxy) -2-hydroxy-3, 3-dimethylbutanamido) propanamido) ethyl) thio) -3-methyl-5-oxopent-2-enoic Acid. CAS No. 6247-73-0. Molecular formula: C27H42N7O19P3S. Mole weight: 893.64.
Thailanstatin A is a splicesosome inhibitor that acts via suppressing RNA-polymerase II. It is effective against cancers, and can be used as a payload for ADCs. Synonyms: 1,6-Dioxaspiro[2.5]octane-5-acetic acid, 7-[(1E,3E)-5-[(2S,3S,5R,6R)-5-[[(2Z,4S)-4-(acetyloxy)-1-oxo-2-penten-1-yl]amino]tetrahydro-3,6-dimethyl-2H-pyran-2-yl]-3-methyl-1,3-pentadien-1-yl]-8-hydroxy-, (3R,5S,7R,8R)-. Grades: 95%. CAS No. 1426953-21-0. Molecular formula: C28H41NO9. Mole weight: 535.63.
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