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A cell-permeable 3-phenyl-aminobenzoate compound that acts as a potent, competitive, reversible, active-site targeting inhibitor of aldo-keto reductase 1C3 (AKR1C3; type 5 17b-hydroxysteroid dehydrogenase) (IC50 = 60nM) with excellent selectivity over other closely related human AKR isoforms (IC50 = 22.7, 15.4, 62.7, >50, and >50uM for and AKR1C1, AKR1C2, AKR1C4, AKR1B1 and AKR1B10, respectively. Exhibits a weak inhibitory effect on cyclooxygenase 1 and 2 (IC50 = 100uM). Shown to efficiently block the AKR1C3-mediated production of testosterone in LNCaP-AKR1C3 cells (~10uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
A metabolite of Celebrex, a Cox-2 inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 170571-01-4. Pack Sizes: 10mg. US Biological Life Sciences.
Effective ligand for the Pd-catalyzed arylation of pyrazoles, indazoles and amino heterocycles. Ligand used in the Pd-catalyzed synthesis of phenols from aryl halides and KOH. Ligand used in the Pd-catalyzed of benzoicacids from aryl halides and CO2. Ligand used in the Pd-catalyzed trifluoromethylation of vinyl sulfonates. Ligand used in the Pd-catalyzed arylation of nitroacetates. Ligand used in the Pd-catalyzed Suzuki-Miyaura cross-coupling of allylboronates and aryl halides. Ligand used in the Pd-catalyzed cyanation of (hetero)arylchlorides and bromides. Ligand used in the Pd-catalyzed C-N cross coupling of sulfinamides and aryl halides. Ligand used in the Pd-catalyzed arylation of cyanamides. Group: Organic phosphine compounds. Alternative Names: DTXSID70469549; t-Bu XPhos; FT-0689983; TC-121258; 2-Di-tert-butylphosphino-2 inverted exclamation marka,4 inverted exclamation marka,6 inverted exclamation marka-triisopropylbiphenyl; tBuXPhos; ditert-butyl-[2-(2,4,6-triisopropylphenyl)phenyl]phosphane; ZINC56961724; 2-Di-tert-butylphosphino-2',4',6'-triisopropylbiphenyl; 2-(di-tert-butylphosphino)-2', 4',6'-triisopropylbiphenyl. CAS No. 564483-19-8. Molecular formula: C29H45P. Mole weight: 424.653g/mol. IUPACName: ditert-butyl-[2-[2,4,6-tri(propan-2-yl)phenyl]phenyl]phosphane. Canonical SMILES: CC (C)C1=CC (=C (C (=C1)C (C)C)C2=CC=CC=C2P (C (C) (C)C)C (C) (C)C)C (C)C. Catalog: ACM5644
Antrafenine dihydrochloride
Antrafenine dihydrochloride. Group: Biochemicals. Alternative Names: 2- [ [7- (Trifluoromethyl) -4-quinolinyl] amino] benzoicacid [4-[3- (trifluoromethyl) phenyl]-1-piperazinyl]ethyl ester hydrochloride. Grades: Highly Purified. CAS No. 55300-30-6. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C30H28Cl2F6N4O2. US Biological Life Sciences.
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Antrafenine Dihydrochloride
Antrafenine Dihydrochloride is the dihydrochloride form of Antrafenine, which is a piperazine derivative drug. It acts as an analgesic and anti-inflammatory drug, but is not widely used. Uses: Antrafenine dihydrochloride acts as an analgesic and anti-inflammatory drug. Synonyms: 2-[[7-(TrifluoroMethyl)-4-quinolinyl]amino]benzoicAcid [4-[3-(TrifluoroMethyl)phenyl]-1-piperazinyl]ethyl Ester dihydrochloride; Benzoicacid, 2-((7-(trifluoromethyl)-4-quinolinyl)amino)-, 2-(4-(3-(trifluoromethyl)phenyl)-1-piperazinyl)ethyl ester, dihydrochloride. Grades: 98%. CAS No. 55300-30-6. Molecular formula: C30H28Cl2F6N4O2. Mole weight: 661.47.
Carboxylic acid celecoxib
Celecoxib Carboxylic Acid is a metabolite of Celecoxib, a Cox-2 inhibitor. Synonyms: 4-[1-[4-(Aminosulfonyl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-5-yl]benzoicAcid; Celebrex Carboxylic Acid. Grades: > 95%. CAS No. 170571-01-4. Molecular formula: C17H12F3N3O4S. Mole weight: 411.36.
Celecoxib carboxylic acid
Celecoxib carboxylic acid. Group: Biochemicals. Alternative Names: 4-[1-[4-(Aminosulfonyl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-5-yl]benzoicacid; Celebrex carboxylic acid. Grades: Highly Purified. CAS No. 170571-01-4. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C17H12F3N3O4S. US Biological Life Sciences.
Worldwide
Celecoxib Carboxylic Acid Methyl Ester
Intermediate for the preparation of Celebrex Carboxylic Acid. Group: Biochemicals. Alternative Names: 4-[1-[4-(Aminosulfonyl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-5-yl]benzoicAcid Methyl Ester; Celebrex Carboxylic Acid Methyl Ester. Grades: Highly Purified. CAS No. 1189893-75-1. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
E7046
E7046 is an orally bioavailable and specific type 4 prostaglandin E2 (PGE2) receptor EP antagonist (IC50= 13.5 nM) (Ki= 23.14 nM), with anti-tumor activities. Synonyms: E7046; E-7046; E 7046. 4-[(1S)-1-[[3-(difluoromethyl)-1-methyl-5-[3-(trifluoromethyl)phenoxy]pyrazole-4-carbonyl]amino]ethyl]benzoicacid. CAS No. 1369489-71-3. Molecular formula: C22H18F5N3O4. Mole weight: 483.39.
Medication used to alleviate joint and muscle pain. Group: Biochemicals. Alternative Names: 2-[[3- (Trifluoromethyl) phenyl]amino]benzoicAcid 2-(2-Hydroxyethoxy)ethyl Ester; 2-(2-Hydroxyethoxy)ethyl Fufenamate; Bayrogel; Reumon; Rheumon; Traumon Gel. Grades: Highly Purified. CAS No. 30544-47-9. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
Etofenamate
Medication used to alleviate joint and muscle pain. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: TVX485; TVX-485; TVX 485; WHR-5020; WHR 5020; WHR5020; Etofenamate; Bay d 1107; Bayrogel; Rheumon. 2-[[3- (Trifluoromethyl) phenyl]amino]benzoicAcid 2-(2-Hydroxyethoxy)ethyl Ester; 2-(2-Hydroxyethoxy)ethyl Fufenamate; Bayrogel; Reumon; Rheumon; Traumon Gel. Grades: >98%. CAS No. 30544-47-9. Molecular formula: C18H18F3NO4. Mole weight: 369.34.
Etofenamate O-Glucuronide
A derivative of Etofenamate. Etofenamate is a non-steroidal anti-inflammatory drug used for the treatment of joint and muscular pain. Synonyms: 2-[[3- (Trifluoromethyl) phenyl]amino]benzoicAcid 2-(2-Hydroxyethoxy)ethyl Ester O-β-D-Glucuronide; 2-(2-Hydroxyethoxy)ethyl Fufenamate O-β-D-Glucuronide. Grades: > 95%. Molecular formula: C24H27F3NO10. Mole weight: 546.48.