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2-Aminoquinoline (2-Quinolinamine) is a promising compound as bioavailable nNOS inhibitor but suffers from low human nNOS inhibition, low selectivity versus human eNOS, and significant binding to other CNS targets. 2-Aminoquinoline exhibits antiviral activity against the vaccinia virus. 2-Aminoquinoline has the potential for the research of antineurodegenerative agents [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2-Quinolinamine. CAS No. 580-22-3. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-W007524.
2-Aminoquinoline
2-Aminoquinoline (2-Quinolinamine) is a promising compound as bioavailable nNOS inhibitor but suffers from low human nNOS inhibition, low selectivity versus human eNOS, and significant binding to other CNS targets. 2-Aminoquinoline exhibits antiviral activity against the vaccinia virus. 2-Aminoquinoline has the potential for the research of antineurodegenerative agents. Group: Inhibitors. CAS No. 580-22-3. Molecular formula: C9H8N2. Mole weight: 144.17. Appearance: White to Brown Powder or Solid. Purity: 0.97. Canonical SMILES: NC1=NC2=CC=CC=C2C=C1. Catalog: ACM580223.
2-Aminoquinoline
2-Aminoquinoline. Group: Biochemicals. Grades: Reagent Grade. CAS No. 580-22-3. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
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2-Chloro-3-aminoquinoline
Heterocyclic Organic Compound. CAS No. 116632-54-3. Catalog: ACM116632543.
4-Aminoquinoline ≥95% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g, 25g. US Biological Life Sciences.
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5-Aminoquinoline
5-Aminoquinoline. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5g. US Biological Life Sciences.
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5-Chloro-8-aminoquinoline
Heterocyclic Organic Compound. Alternative Names: 5-Chloro-8-aminoquinoline;5-Chloroquinolin-8-amine. CAS No. 5432-9-7. Molecular formula: C9H7ClN2. Catalog: ACM1290288.
6-Aminoquinoline
25g Pack Size. Group: Amines, Analytical Reagents. Formula: C9H8N2. CAS No. 580-15-4. Prepack ID 88324018-25g. Molecular Weight 144.17. See USA prepack pricing.
6-Aminoquinoline
5g Pack Size. Group: Amines, Analytical Reagents. Formula: C9H8N2. CAS No. 580-15-4. Prepack ID 88324018-5g. Molecular Weight 144.17. See USA prepack pricing.
6-Aminoquinoline
6-Aminoquinoline is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 580-15-4. Pack Sizes: 10 g; 25 g. Product ID: HY-W007404.
6-Aminoquinoline
6-Aminoquinoline is used in the preparation of diaminopyrimidine derivatives as 5-HT4 receptor agonists. Group: Biochemicals. Alternative Names: (Quinolin-6-yl)amine; 6-Quinolylamine; NSC 58388. Grades: Highly Purified. CAS No. 580-15-4. Pack Sizes: 5g. US Biological Life Sciences.
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6-Aminoquinoline 99+% (HPLC)
6-Aminoquinoline 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g, 250g. US Biological Life Sciences.
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6-Aminoquinoline-N-hydroxy-succinimidyl carbamate
6-Aminoquinoline-N-hydroxy-succinimidyl carbamate is suitable for amino acid or protein sequence analysis by HPLC with fluorescence detection. Uses: 6-aminoquinoline-n-hydroxy-succinimidyl carbamate is used as derivatization regent for detecting hydrogen cyanamide in fruit. Synonyms: 2,5-Dioxopyrrolidin-1-yl quinolin-6-ylcarbamate; AQC; AHC reagent; AccQ.Fluor; AccQ·Tag. Grades: 95%. CAS No. 148757-94-2. Molecular formula: C14H11N3O4. Mole weight: 285.25.
6-Chloro-8-aminoquinoline
6-Chloro-8-aminoquinoline. Group: Biochemicals. Alternative Names: 6-Chloro-8-quinolinamine; 8-Amino-6-chloroquinoline; NSC 2798. Grades: Highly Purified. CAS No. 5470-75-7. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C9H7ClN2. US Biological Life Sciences.
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7-Aminoquinoline
7-Aminoquinoline. Group: Biochemicals. Grades: Highly Purified. CAS No. 580-19-8. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C9H8N2. US Biological Life Sciences.
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8-Aminoquinoline
8-Aminoquinoline. Group: Biochemicals. Grades: Highly Purified. CAS No. 578-66-5. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C9H8N2. US Biological Life Sciences.
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8-Aminoquinoline
8-Aminoquinoline is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 578-66-5. Pack Sizes: 5 g; 10 g. Product ID: HY-W007317.
8-Aminoquinoline has been used in: preparation of base-stabilized terminal borylene complex of osmium spectrophotometric determination of bivalent palladium. Group: Quinolines. Alternative Names: DTXSID4060369; AN-21475; AC1Q51CD; A3000/0126362; 8-amino quinoline; PS-5383; PubChem7574; quinolin-8-yl-amine; RTC-062235; AB00375631-02. CAS No. 578-66-5. Molecular formula: C9H8N2. Mole weight: 144.177g/mol. IUPACName: quinolin-8-amine. Canonical SMILES: C1=CC2=C(C(=C1)N)N=CC=C2. ECNumber: 209-427-9. Catalog: ACM578665.
1,4-bis(7-Chloroquinolin-4-yl)piperazine
1,4-bis(7-Chloroquinolin-4-yl)piperazine, is a derivative of aminoquinolines, that have been shown to have antiparasitic, antimicrobial and antifungal activities. Group: Biochemicals. Grades: Highly Purified. CAS No. 31502-87-1. Pack Sizes: 25mg, 250mg. Molecular Formula: C22H18Cl2N4, Molecular Weight: 409.31. US Biological Life Sciences.
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2-(Benzo[b]thiophen-5-yl)ethanol
2-(Benzo[b]thiophen-5-yl)ethanol is derived from 5-Bromobenzo[b]thiophene (B680425), which is used as a reactant in the preparation of 4-aminoquinolines and tetraoxanes displaying antimalarial activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 96803-30-4. Pack Sizes: 50mg, 250mg. Molecular Formula: C10H10OS, Molecular Weight: 178.25. US Biological Life Sciences.
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3-Bromoquinolin-8-amine
3-Bromoquinolin-8-amine acts as a reagent for the synthesis and structure activity relationship of 3-(arylsulfonyl)-8-(piperidin-4-yl amino)quinoline derivatives as 5-HT6 receptor antagonists for the treatment of Alzheimer's disease and Schizophrenia. Also acts as a reagent for the synthesis of certain 8-aminoquinolines and antimalarias. Group: Biochemicals. Grades: Highly Purified. CAS No. 139399-67-0. Pack Sizes: 50mg, 250mg. Molecular Formula: C9H7BrN2, Molecular Weight: 223.07. US Biological Life Sciences.
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4,7-Dichloroquinoline
4,7-dichloroquinoline is used in the synthesis of hybrid aminoquinoline-triazine derivatives that show anti-microbial activity. In addition, it is used in the synthesis of novel oxazolidinones as anti-microbial agents showing efficacy against common bacterial strains. Chloroquinoline impurity. Group: Quinolines. Alternative Names: 4,7-dichloRCHINOLIN;4,7-dichloroQUINOLINE FOR SYNTHESIS;4,7-dichloroquinoline,tech.;4,7-dichloLROQUINOLINE. CAS No. 86-98-6. Molecular formula: C9H5Cl2N. Mole weight: 198.05. Appearance: Yellow to brown crystals. Purity: ≥99%. Density: 1.407 g/cm³. ECNumber: 201-714-7. Catalog: ACM86986.
4,7-Dichloroquinoline (NSC 593)
4,7-Dichloroquinoline is used in the synthesis of hybrid aminoquinoline-triazine derivatives that show anti-microbial activity. In addition, it is used in the synthesis of novel oxazolidinones as anti-microbial agents showing efficacy against common bacterial strains. Chloroquinoline impurity. Group: Biochemicals. Alternative Names: NSC 593. Grades: Highly Purified. CAS No. 86-98-6. Pack Sizes: 50g, 100g, 250g, 500g, 1Kg. Molecular Formula: C?H?Cl?N. US Biological Life Sciences.
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8-Amino-6-methoxyquinoline-d5
Isotope labelled 8-Amino-6-methoxyquinoline exhibits oxidizing properties as well as potential anti-tuberculosis application with its antimycobacterial messages as well. Group: Biochemicals. Alternative Names: 6-Methoxy-8-quinolinamine-d5; 8-Amino-6-methoxy-quinoline-d5; 6-Methoxy-8-aminoquinoline-d5; 6-Methoxyquinolin-8-amine-d5; 6-Methoxyquinolin-8-ylamine-d5; 8-Amino-6-methoxyquinoline-d5; Amichin-d5; NSC 119507-d5; NSC 119508-d5; NSC 13573-d5; WR 15081-d5. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
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Amodiaquine
Amodiaquine (Amodiaquin), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor. Amodiaquine is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC 50 of ~20 μM. Anti-inflammatory effect [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Amodiaquin. CAS No. 86-42-0. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B1322A.
Amodiaquine
Amodiaquine (Amodiaquin), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor. Amodiaquine is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC50 of ~20 μM. Anti-inflammatory effect. Group: Inhibitors. Alternative Names: 4- ( (7-chloro-4-quinolyl)amino)-alpha- (diethylamino)-o-creso; 4- ( (7-Chloro-4-quinolyl)amino)-alpha- (diethylamino)-o-cresol; 4-[ (7-Chloro-4-quinolinyl)amino]-alpha- (diethylamino)-o-cresol; 7-Chloro-4- (3-diethylaminomethyl-4-hydroxyphenylamino)quinoline; Amodia. CAS No. 86-42-0. Molecular formula: C20H22ClN3O. Mole weight: 355.86. Appearance: Cyrstalline Solid. Canonical SMILES: OC1=CC=C (NC2=CC=NC3=CC (Cl)=CC=C23)C=C1CN (CC)CC. Density: 1.258. Catalog: ACM86420.
Amodiaquine-d10
Amodiaquine-d 10 is the deuterium labeled Amodiaquine. Amodiaquine (Amodiaquin), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor. Amodiaquine is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC50 of ~20 μM. Anti-inflammatory effect[1][2][3][4]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1189449-70-4. Pack Sizes: 1 mg. Product ID: HY-B1322AS.
Amodiaquine-d10
Amodiaquine-d10 is the deuterium labeled Amodiaquine. Amodiaquine (Amodiaquin), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor. Amodiaquine is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC50 of ~20 μM. Anti-inflammatory effect. Group: Inhibitors. Alternative Names: 4-[(7-Chloro-4-quinolinyl)amino]-2-[(diethylamino-d10)methyl]phenol; 4-[(7-Chloro-4-quinolyl)amino]-α -(diethylamino-d10)-o-cresol; Camochin-d10; Camoquin-d10; Camoquinal-d10; Camoquine-d10; Flavoquine-d10; Miaquin-d10; NSC 13453-10; SN-10751-d10. CAS No. 1189449-70-4. Molecular formula: C20H12D10ClN3O. Mole weight: 365.92. Appearance: Pale Yellow Solid. Purity: ≥97.0%. Canonical SMILES: ClC (C=C1)=CC2=C1C (NC3=CC (CN (C ([2H]) ([2H])C ([2H]) ([2H])[2H])C ([2H]) ([2H])C ([2H]) ([2H])[2H])=C (C=C3)O)=CC=N2. Catalog: ACM1189449704.
Amodiaquine dihydrochloride
Amodiaquine dihydrochloride (Amodiaquin dihydrochloride), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor with a K i of 18.6 nM. Amodiaquine dihydrochloride is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC 50 of ~20 μM. Anti-inflammatory effect [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Amodiaquin dihydrochloride. CAS No. 69-44-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1322B.
AQ-13 dihydrochloride
AQ-13 dihydrochloride is an aminoquinoline antimalarial agent that is effective against drug-resistant strains of Plasmodium falciparum. Uses: Scientific research. Group: Signaling pathways. CAS No. 169815-40-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100358.
Carbostyril 124
Suitable as a laser dye. Group: Biochemicals. Alternative Names: 7-Amino-4-methyl-2(1H)-quinolinone; 7-Amino-4-methyl-carbostyril; 2-Hydroxy-4-methyl-7-aminoquinoline; 4-Methyl-7-aminocarbostyril; 7-Amino-2-hydroxy-4-methylquinoline; Carbostyryl 7. Grades: Highly Purified. CAS No. 19840-99-4. Pack Sizes: 200mg. US Biological Life Sciences.
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Hydroxychloroquine
An antimalarial; antirheumatic; lupus erythematosus suppressant. Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer.2 Hydroxychloroquine is an aminoquinoline like chloroquine. It is a commonly prescribed medication in the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and systemic lupus erythematosus.12 Hydroxychloroquine is also used for the prophylaxis of malaria in regions where chloroquine resistance is unlikely. It was developed during World War II as a derivative of quinacrine with less severe side effects. Chloroquine and hydroxychloroquine are both being investigated for the treatment of SARS-CoV-2. Hydroxychloroquine was granted FDA approval on 18 April 1955. Hydroxychloroquine is indicated for the prophylaxis of malaria where chloroquine resistance is not reported, treatment of uncomplicated malaria (caused by P. falciparum, P. malariae, P. ovale, or P. vivax), chronic discoid lupus erythematosus, system Group: Biochemicals. Alternative Names: 2-[{4-[ (7-Chloroquinolin-4-yl)amino]pentyl} (ethyl)amino]ethanol; 7-Chloro-4-[4-[ethyl(2-hydroxyethyl)amino]-1-methylbutylamino]-quinoline; Plaquenil; Oxichloroquine; Oxychloro. Grades: Highly Purified. CAS No. 118-42-3. Pack Sizes: 10mg, 50mg, 100mg. Molecular Formula: C??H??ClN?O, Molecular Weight: 335.87. US Biological Life Sciences.
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Piperaquine Tetraphosphate
Piperaquine is a 4-aminoquinoline derivative used as an antimalarial agent. Piperaquine interferes with physiological function of the food vacuole membrane of the trophozoites leading to autophagocytosis of the parasites. It is commonly used in combination with Dihydroartemisinin for the treatment of multi-drug resistant falciparum malaria. Group: Biochemicals. Alternative Names: 4,4'-(1,3-Propanediyldi-4,1-piperazinediyl)bis[7-chloroquinoline] Tetraphosphate. Grades: Highly Purified. CAS No. 911061-10-4. Pack Sizes: 10mg, 100mg, 250mg, 1g. Molecular Formula: C29H32Cl2N6 4H3PO4, Form: Supplied as an off-white to light beige. US Biological Life Sciences.
Ro 90-7501, under the IUPCA name 2-[2-(4-aminophenyl)-3H-benzimidazol-5-yl]-3H-benzimidazol-5-amine, a type of aminoquinolines, is an inhibitor of Aβ42 fibril assembly so that can reduce Aβ42-induced toxicity (EC50 = 2 μM). Uses: Anti-alzheimer agents; amyloid-β inhibitor. Synonyms: RO 90-7501; RO 90 7501; RO 907501; RO907501; RO-90-7501; 2-[2-(4-aminophenyl)-3H-benzimidazol-5-yl]-3H-benzimidazol-5-amine; Ro 90-7501; 293762-45-5; GNF-Pf-5510; STK367782; CBChromo1_000149; AC1LGN68; Cambridge id 5180073; CBDivE_006377; R0529_SIGMA; CHEMBL578741; SCHEMBL10002475; STOCK2S-20922; CTK8E9490; DTXSID80356431; HMS3262E21; HMS3269A19; Tox21_500670; ZINC18206988; AKOS000635167; AKOS001483260; CCG-221974; LP00670; MCULE-7528949788; NCGC00094031-06; NCGC00261355-01; BAS 03420670; HE063215; HE332505; ST078196; AB00074940-01; AG-690/09405007; BRD-K58299615-001-02-7; 3B1-004024; 2'-(4-aminophenyl)-[2,5'-bi-1H-benzimidazol]-5-amine; 2'-(4-aminophenyl)-1H,1'H-2,5'-bibenzimidazol-5-amine; 2-[2-(4-aminophenyl)benzimidazol-6-yl]benzimidazole-6-ylamine; 2'-(4-Amino-phenyl)-3H,3'H-[2,5']bibenzoimidazolyl-5-ylamine; 2-[2-(4-aminophenyl)-3H-benzimidazol-5-yl]-3H-benzimidazol-5-amine; Ro 90-7501|2'-(4-Aminophenyl)-[2,5'-bi-1H-benzimidazol]-5-amine; 2-[2-(4-aminophenyl)-1H-1,3-benzodiazol-6-yl]-1H-1,3-benzodiazol-6-amine; 2-[2-(4-AMINOPHENYL)-3H-1,3-BENZODIAZOL-5-YL]-3H-1,3-BENZODIAZOL-5-AMINE. CAS No. 293762-45-5. Molecular formula: C20H16N6. Mole weight: 340.39.
Tafenoquine
Tafenoquine is an oral active and an 8-aminoquinoline antimalaria drug. It is being investigated as a potential treatment for malaria, as well as for malaria prevention.It is for treatment of the hypnozoite stages of Plasmodium vivax and Plasmodium ovale that are responsible for relapse of these malaria species even when the blood stages are successfully cleared. It targets leishmania respiratory complex III and induces apoptosis. It has a long half-life of approximately 14 days and is generally safe and well tolerated, thus therefore a single treatment may be sufficient to clear hypnozoites. It was manufactured by GlaxoSmithKline and in clinic phase 3 trials. Uses: Tafenoquine is being investigated as a potential treatment for malaria, as well as for malaria prevention.it is for treatment of the hypnozoite stages of plasmodium vivax and plasmodium ovale. Synonyms: 4-[5-[3-(Trifluoromethyl)phenoxy]-2, 6-dimethoxy-4-methyl-8-quinolinylamino]-1-pentanamine; 8-[(4-Amino-1-methylbutyl)amino]-2, 6-dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinoline; N4-(2, 6-diMethoxy-4-Methyl-5-(3-(trifluoroMethyl)phenoxy)quinolin-8-yl)pentane-1, 4-diamine; WR-238605; WR238605; Etaquine. Grades: >98%. CAS No. 106635-80-7. Molecular formula: C24H28F3N3O3. Mole weight: 463.50.
Tafenoquine
Tafenoquine (WR 238605) is an 8-aminoquinoline. Tafenoquine is an anti-malarial prophylactic agent [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WR 238605. CAS No. 106635-80-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111529.
Tafenoquine Succinate
Tafenoquine Succinate (WR 238605 Succinate) is an 8-aminoquinoline. Tafenoquine is an anti-malarial prophylactic agent [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WR 238605 Succinate. CAS No. 106635-81-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111529A.
WH-15
WH-15 is a fluorogenic PLC reporter with K m value of 49; 30, 86.1 μM for PLC-γ1, PLC-δ1, PLC-β2, respectively. WH-15 can be cleaved in a cascade reaction to generate fluorescent 6-aminoquinoline. WH-15 can be used to respond to imaging PLC activity in live cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1264748-47-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-135799.
1-(5-Aminoquinolin-6-yl)piperidin-4-ol
1-(5-Aminoquinolin-6-yl)piperidin-4-ol. Group: Biochemicals. Grades: Highly Purified. CAS No. 1157642-42-6. Pack Sizes: 100mg, 250mg. Molecular Formula: C14H17N3O, Molecular Weight: 243.3. US Biological Life Sciences.
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1-(5-Aminoquinolin-8-yl)piperidin-4-ol
1-(5-Aminoquinolin-8-yl)piperidin-4-ol. Group: Biochemicals. Grades: Highly Purified. CAS No. 1154632-96-8. Pack Sizes: 100mg, 250mg. Molecular Formula: C14H17N3O, Molecular Weight: 243.3. US Biological Life Sciences.
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3-Amino-6-nitro-4-phenyl-2(H)-quinolinone
3-Amino-6-nitro-4-phenyl-2(H)-quinolinone is a chemical reagent used in the preparation of 3-aminoquinolin-2-one derivatives as ways to stave off parasitic infections like leishmaniasis and trypanosomiasis. Nitrazepam (N490140), impurity. Group: Biochemicals. Grades: Highly Purified. CAS No. 36020-93-6. Pack Sizes: 5mg, 10mg. Molecular Formula: C15H11N3O3, Molecular Weight: 281.27. US Biological Life Sciences.