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| Product | Description | |
|---|---|---|
| Amyloid ? 13-16 human | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Amyloid ? 1-40 rat | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Amyloid ? 1-42 rat | ?90% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Amyloid ? 17-42 human | ?80% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Amyloid ? 42-1 reverse human | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Amyloid β-peptide (1-40) rat | Amyloid β-peptide (1-40) (rat) is the rat form of the amyloid β-peptide found in plaques, which is the major constituent observed in the brain of Alzheimer's disease. It is the prone-to-aggregation product of amyloid precursor protein proteolytic cleavage. It is shown to have both neurotrophic and neurotoxic effects. Synonyms: β-Amyloid (1-40), rat; H-Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Glu-Val-Arg-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH; L-alpha-aspartyl-L-alanyl-L-alpha-glutamyl-L-phenylalanyl-glycyl-L-histidyl-L-alpha-aspartyl-L-seryl-glycyl-L-phenylalanyl-L-alpha-glutamyl-L-valyl-L-arginyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-valyl-glycyl-L-seryl-L-asparagyl-L-lysyl-glycyl-L-alanyl-L-isoleucyl-L-isoleucyl-glycyl-L-leucyl-L-methionyl-L-valyl-glycyl-glycyl-L-valyl-L-valine; Rat amyloid-beta peptide 1-40; Rat amyloid-β peptide 1-40; Amyloid b-Protein (1-40) (Mouse, rat). Grades: ≥95%. CAS No. 144409-98-3. Molecular formula: C190H291N51O57S. Mole weight: 4233.76. |  |
| Amyloid β-peptide (1-42) human | Amyloid β-Peptide (12-28) (human), an Amyloid β-peptide fragment, binds with high affinity to α7-nicotinic ACh receptors. It impairs memory retention following central administration in mice. Uses: Implicated in alzheimer's disease. Synonyms: β-Amyloid (1-42), human; beta-Amyloid (1-42) human; Amyloid Beta Protein Fragment 1-42; H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH; L-alpha-aspartyl-L-alanyl-L-alpha-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-alpha-aspartyl-L-seryl-glycyl-L-tyrosyl-L-alpha-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-valyl-glycyl-L-seryl-L-asparagyl-L-lysyl-glycyl-L-alanyl-L-isoleucyl-L-isoleucyl-glycyl-L-leucyl-L-methionyl-L-valyl-glycyl-glycyl-L-valyl-L-valyl-L-isoleucyl-L-alanine; Abeta 42 protein; amyloid beta-protein (1-42). Grades: ≥95%. CAS No. 107761-42-2. Molecular formula: C203H311N55O60S. Mole weight: 4514.04. | |
| Amyloid β-peptide (1-42) (rat) | Amyloid β-peptide (1-42) (rat) is the rat form of the predominant amyloid β-peptide found in plaques associated with Alzheimer's disease. It could lead to a large shift in the bax/bcl-2 ratio in favour of pro-apoptotic bax. It is neurotoxic. Synonyms: Amyloid β-Protein (1-42) (mouse, rat); beta-Amyloid Peptide (1-42) (rat/mouse). CAS No. 166090-74-0. Molecular formula: C199H307N53O59S. Mole weight: 4418.02. | |
| Amyloid β-Peptide (1-43) (human) | Amyloid β-Peptide (1-43) (human) is the minor component of neuritic plaques, which is the primary constituent of senile plaques and cerebrovascular deposits in Alzheimer's disease and Down's syndrome. It is neurotrophic and neurotoxic. Synonyms: β-Amyloid (1-43); Amyloid β-Protein Fragment 1-43; H-DL-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-D-Glu-D-Asp-D-Val-Gly-D-Ser-D-Asn-D-Lys-Gly-D-Ala-D-xiIle-D-xiIle-Gly-D-Leu-D-Met-D-Val-Gly-Gly-D-Val-D-Val-D-xiIle-D-Ala-D-xiThr-OH. CAS No. 134500-80-4. Molecular formula: C207H318N56O62S. Mole weight: 4615.19. | |
| Amyloid beta-peptide (25-35) | Amyloid beta-peptide(25-35), the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide, is functionally required for the neurotrophic and neurotoxic effects associated with Alzheimer's disease. Synonyms: H-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-OH; glycyl-L-seryl-L-asparagyl-L-lysyl-glycyl-L-alanyl-L-isoleucyl-L-isoleucyl-glycyl-L-leucyl-L-methionine; Amyloid β-Protein (25-35); Amyloid-Protein (25-35). CAS No. 131602-53-4. Molecular formula: C45H81N13O14S. Mole weight: 1060.27. | |
| Amyloid beta-peptide (25-35) 2TFA | Amyloid beta-peptide (25-35) 2TFA, the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide, is functionally required for the neurotrophic and neurotoxic effects associated with Alzheimer's disease. Synonyms: GSNKGAIIGLM 2TFA; H-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-OH.2TFA; glycyl-L-seryl-L-asparagyl-L-lysyl-glycyl-L-alanyl-L-isoleucyl-L-isoleucyl-glycyl-L-leucyl-L-methionine trifluoroacetic acid; Amyloid β-peptide (25-35) trifluoroacetate; Aβ25-35 trifluoroacetate; Eledoisin, 1-glycine-2-L-serine-3-L-asparagine-5-glycine-7-L-isoleucine-11-L-methionine-, trifluoroacetate; Human β-amyloid peptide (25-35) trifluoroacetate; β-Amyloid fragment(25-35) trifluoroacetate; β-Amyloid peptide(25-35) trifluoroacetate. Grades: ≥95%. Molecular formula: C49H83F6N13O18S. Mole weight: 1288.32. | |
| Amyloid β-peptide (42-1) human | Amyloid β-peptide (42-1) (human), is the predominant form of amyloid β-peptide found in the brains of patients with Alzheimer's disease. Uses: Implicated in alzheimer's disease. Synonyms: H-Ala-Ile-Val-Val-Gly-Gly-Val-Met-Leu-Gly-Ile-Ile-Ala-Gly-Lys-Asn-Ser-Gly-Val-Asp-Glu-Ala-Phe-Phe-Val-Leu-Lys-Gln-His-His-Val-Glu-Tyr-Gly-Ser-Asp-His-Arg-Phe-Glu-Ala-Asp-OH; L-alanyl-L-isoleucyl-L-valyl-L-valyl-glycyl-glycyl-L-valyl-L-methionyl-L-leucyl-glycyl-L-isoleucyl-L-isoleucyl-L-alanyl-glycyl-L-lysyl-L-asparagyl-L-seryl-glycyl-L-valyl-L-alpha-aspartyl-L-alpha-glutamyl-L-alanyl-L-phenylalanyl-L-phenylalanyl-L-valyl-L-leucyl-L-lysyl-L-glutaminyl-L-histidyl-L-histidyl-L-valyl-L-alpha-glutamyl-L-tyrosyl-glycyl-L-seryl-L-alpha-aspartyl-L-histidyl-L-arginyl-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-aspartic acid; Amyloid beta (42-1) human; Amyloid b-Protein (42-1). Grades: ≥95%. CAS No. 317366-82-8. Molecular formula: C203H311N55O60S. Mole weight: 4514.04. | |
| Amyloid β-Protein 10-20 | Amyloid β protein (10-20) is a fragment of Amyloid β peptide that may be used in the study of neurological diseases. Synonyms: H-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-OH; L-tyrosyl-L-alpha-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanine; Amyloid b-Protein (10-20); Amyloid B-protein fragment 10-20. Grades: ≥95%. CAS No. 152286-31-2. Molecular formula: C71H99N17O16. Mole weight: 1446.65. | |
| Amyloid β-Protein 10-20 acetate | Amyloid β-Protein (10-20) acetate is a fragment of Amyloid β peptide that may be used in the study of neurological diseases. Synonyms: H-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-OH.CH3CO2H; L-tyrosyl-L-alpha-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanine acetic acid. Grades: ≥95%. Molecular formula: C73H103N17O18. Mole weight: 1506.65. | |
| Amyloid β-Protein (1-12) | Synonyms: H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-OH; L-alpha-aspartyl-L-alanyl-L-alpha-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-alpha-aspartyl-L-seryl-glycyl-L-tyrosyl-L-alpha-glutamyl-L-valine. Grades: ≥95%. CAS No. 142047-91-4. Molecular formula: C61H85N17O23. Mole weight: 1424.45. | |
| Amyloid β-Protein (11-42) | Synonyms: β Amyloid (11-42); H-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH; L-alpha-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-valyl-glycyl-L-seryl-L-asparagyl-L-lysyl-glycyl-L-alanyl-L-isoleucyl-L-isoleucyl-glycyl-L-leucyl-L-methionyl-L-valyl-glycyl-glycyl-L-valyl-L-valyl-L-isoleucyl-L-alanine. Grades: ≥95%. CAS No. 157802-70-5. Molecular formula: C152H244N40O42S. Mole weight: 3335.87. | |
| Amyloid β-Protein (1-24) | Synonyms: β-Amyloid (1-24); H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-OH; L-alpha-aspartyl-L-alanyl-L-alpha-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-alpha-aspartyl-L-seryl-glycyl-L-tyrosyl-L-alpha-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-valine. Grades: ≥95%. CAS No. 138648-77-8. Molecular formula: C130H183N35O40. Mole weight: 2876.05. | |
| Amyloid β-Protein (1-37) | Amyloid β-Protein (1-37) is a fragment of amyloid β-protein cleaved from amyloid precursor protein (APP) that is moderately associated with Mini-Mental State Examination (MMSE) scores in Alzheimer disease. Synonyms: H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-OH; L-alpha-aspartyl-L-alanyl-L-alpha-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-alpha-aspartyl-L-seryl-glycyl-L-tyrosyl-L-alpha-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-valyl-glycyl-L-seryl-L-asparagyl-L-lysyl-glycyl-L-alanyl-L-isoleucyl-L-isoleucyl-glycyl-L-leucyl-L-methionyl-L-valyl-glycine. Grades: ≥90%. CAS No. 186359-67-1. Molecular formula: C182H274N50O55S. Mole weight: 4074.55. | |
| Amyloid β-Protein (1-39) | Synonyms: H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-OH. Grades: ≥95%. CAS No. 115427-62-8. Molecular formula: C189H286N52O57S. Mole weight: 4230.73. | |
| Amyloid β-Protein (1-40) amide | Synonyms: β-Amyloid (1-40), amide; H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-NH2. Grades: ≥95%. CAS No. 203460-31-5. Molecular formula: C194H296N54O57S. Mole weight: 4328.88. | |
| Amyloid β-Protein (1-40)-Lys(biotinyl) amide | Amyloid β-Protein (1-40)-Lys(biotinyl) amide is used for immobilization of Aβ40. The biotinylation of the peptide and the location of the biotin portion (N- or C-terminus) seem to influence aggregation behavior. Similar effects are observed at the N- or C-terminal of Aβ42 biotinylation. Synonyms: Abeta (1-40) Lys (Biotin) amide; H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Lys(biotinyl)-NH2. Grades: ≥95%. Molecular formula: C210H322N58O60S2. Mole weight: 4683.35. | |
| Amyloid β-Protein (1-42)-Lys(biotinyl) amide | Amyloid β-Protein (1-42)-Lys(biotinyl) amide is used for immobilization of Aβ42. N-terminal biotinylated and C-terminal biotinylated Aβ42 binding may behave differently on surfaces. Synonyms: Beta-Amyloid (1-42)-Lys(biotin) amide; H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-Lys(biotinyl)-NH2. Grades: ≥95%. Molecular formula: C219H338N60O62S2. Mole weight: 4867.53. | |
| Amyloid β-Protein (1-42) (scrambled) | Amyloid β-Protein (1-42) (scrambled) is the inactive control for Aβ1-42. Synonyms: β-Amyloid (1-42) Scrambled; H-Ala-Ile-Ala-Glu-Gly-Asp-Ser-His-Val-Leu-Lys-Glu-Gly-Ala-Tyr-Met-Glu-Ile-Phe-Asp-Val-Gln-Gly-His-Val-Phe-Gly-Gly-Lys-Ile-Phe-Arg-Val-Val-Asp-Leu-Gly-Ser-His-Asn-Val-Ala-OH. Grades: ≥95%. CAS No. 1678415-52-5. Molecular formula: C203H311N55O60S. Mole weight: 4514.10. | |
| Amyloid β-Protein (1-6) | The experiments using sub-peptides of Aβ42 reveals that the epitope identified by antibody A8 is located in the 1-6 region of A&beta. Synonyms: H-Asp-Ala-Glu-Phe-Arg-His-OH; L-α-Aspartylalanyl-L-α-glutamyl-L-phenylalanyl-L-arginyl-L-histidine; H-DAEFRH-OH. Grades: ≥95%. CAS No. 214550-64-8. Molecular formula: C33H47N11O11. Mole weight: 773.79. | |
| Amyloid β-Protein (16-22) | Amyloid β-Protein (16-22) is a self-assembling Aβ sequence. Synonyms: H-Lys-Leu-Val-Phe-Phe-Ala-Glu-OH; L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-glutamic acid. Grades: ≥95%. CAS No. 153247-41-7. Molecular formula: C43H64N8O10. Mole weight: 853.02. | |
| Amyloid β-Protein (1-6) amide | Experiments using sub-peptides of Aβ42 show that the epitope identified by antibody A8 is located in the 1-6 region of A&beta. Synonyms: L-Histidinamide, L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-L-arginyl-; H-Asp-Ala-Glu-Phe-Arg-His-NH2; H-DAEFRH-NH2; L-alpha-aspartyl-L-alanyl-L-alpha-glutamyl-L-phenylalanyl-L-arginyl-L-histidinamide. Grades: ≥95%. CAS No. 903883-21-6. Molecular formula: C33H48N12O10. Mole weight: 772.81. | |
| Amyloid β-Protein (17-40) | Cleavage of APP by alpha- and gamma-secretase (i.e. the non-amyloidogenic pathway) yields p3 peptide, a mix of Aβ 17-40 and Aβ 17-42. P3 is a major component of diffuse plaques observed in AD brains and preamyloid plaques in patients with Down syndrome. Synonyms: β-Amyloid (17-40); H-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH; L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-valyl-glycyl-L-seryl-L-asparagyl-L-lysyl-glycyl-L-alanyl-L-isoleucyl-L-isoleucyl-glycyl-L-leucyl-L-methionyl-L-valyl-glycyl-glycyl-L-valyl-L-valine; Amyloid β-Protein Fragment 17-40. Grades: ≥90%. CAS No. 156790-69-1. Molecular formula: C110H178N26O31S. Mole weight: 2392.85. | |
| Amyloid β-Protein (17-42) | Amyloid β-Protein (17-42) is the cleavage of APP by α- and γ-secretase (i.e. the non-amyloidogenic pathway) to produce P3 peptide, a mixture of Aβ 17-40 and Aβ 17-42. Aβ 17-42 contains two hydrophobic patches (L17-A21 and A30-A42) and a turn region (E22-G29), which are critical in determining aggregation and toxicity and form the strand-loop-strand conformation in the fibrils. Synonyms: H-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH; beta-Amyloid peptide 17-42; L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-valyl-glycyl-L-seryl-L-asparagyl-L-lysyl-glycyl-L-alanyl-L-isoleucyl-L-isoleucyl-glycyl-L-leucyl-L-methionyl-L-valyl-glycyl-glycyl-L-valyl-L-valyl-L-isoleucyl-L-alanine; Aβ 17-42. Grades: ≥90%. CAS No. 155178-13-5. Molecular formula: C119H194N28O33S. Mole weight: 2577.08. | |
| Amyloid beta-protein(29-40) | Amyloid beta-protein(29-40). Uses: Designed for use in research and industrial production. Additional or Alternative Names: Aβ(30-40). Product Category: Heterocyclic Organic Compound. CAS No. 184865-04-1. Molecular formula: C49H88N12O13S. Mole weight: 1085.36. Purity: 0.96. IUPACName: amyloid β-protein(30-40). Product ID: ACM184865041. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Amyloid β-Protein (33-42) | Amyloid β-Protein (33-42) is a partial sequence of β-amyloid protein, which is used to raise antibodies against Aβ 1-42. Synonyms: APP770 (704-713); H-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH; glycyl-L-leucyl-L-methionyl-L-valyl-glycyl-glycyl-L-valyl-L-valyl-L-isoleucyl-L-alanine; L-Alanine, glycyl-L-leucyl-L-methionyl-L-valylglycylglycyl-L-valyl-L-valyl-L-isoleucyl-; β-Amyloid (33-42). Grades: ≥95% by HPLC. CAS No. 178949-81-0. Molecular formula: C41H74N10O11S. Mole weight: 915.15. | |
| Amyloid β-Protein (3-40) | Synonyms: β-Amyloid (3-40); H-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH. Grades: ≥95%. CAS No. 157884-70-3. Molecular formula: C187H285N51O54S. Mole weight: 4143.63. | |
| Amyloid β-Protein (3-42) | With the development of AD, N-terminal truncation of Aβ42 may be formed in increased amounts. Amyloid β-Protein (3-42) is a precursor of Pyr-peptide. The resistance of (Pyr3)-Aβ 3-42 positive plaque to age-dependent degradation may be due to its high stability and aggregation tendency. Synonyms: Aβ (3-42); H-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH. Grades: ≥95%. CAS No. 157884-74-7. Molecular formula: C196H301N53O56S. Mole weight: 4327.94. | |
| Amyloid β-Protein (40-1) | Amyloid β-Protein (40-1) is an inactive control of Amyloid β-Protein (1-40). Synonyms: β-Amyloid (40-1); H-Val-Val-Gly-Gly-Val-Met-Leu-Gly-Ile-Ile-Ala-Gly-Lys-Asn-Ser-Gly-Val-Asp-Glu-Ala-Phe-Phe-Val-Leu-Lys-Gln-His-His-Val-Glu-Tyr-Gly-Ser-Asp-His-Arg-Phe-Glu-Ala-Asp-OH; L-valyl-L-valyl-glycyl-glycyl-L-valyl-L-methionyl-L-leucyl-glycyl-L-isoleucyl-L-isoleucyl-L-alanyl-glycyl-L-lysyl-L-asparagyl-L-seryl-glycyl-L-valyl-L-alpha-aspartyl-L-alpha-glutamyl-L-alanyl-L-phenylalanyl-L-phenylalanyl-L-valyl-L-leucyl-L-lysyl-L-glutaminyl-L-histidyl-L-histidyl-L-valyl-L-alpha-glutamyl-L-tyrosyl-glycyl-L-seryl-L-alpha-aspartyl-L-histidyl-L-arginyl-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-aspartic acid. Grades: ≥95%. CAS No. 144409-99-4. Molecular formula: C194H295N53O58S. Mole weight: 4329.86. | |
| Amyloid β-Protein (4-42) | Amyloid β-Protein (4-42) is one of the earliest and most prominent Aβ species deposited in AD brain. In familial AD patients with V261I PS1 mutation, it was found to be a component of cotton boll plaques. It has also been found in amyloid deposits in vascular dementia and familial Danish dementia patients. These results suggest that Aβ 4-42 May be involved in the development of various CNS diseases. Synonyms: Aβ (4-42); H-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH. Grades: ≥95%. CAS No. 157884-72-5. Molecular formula: C191H294N52O53S. Mole weight: 4198.82. | |
| Amyloid β-Protein (5-42) | Amyloid β-Protein (5-42), produced by caspase acting on amyloid precursor proteins, deposits in the alzheimer's brain but less prone to aggregation. Synonyms: Aβ (5-42); H-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH. Grades: ≥95% by HPLC. CAS No. 1678415-97-8. Molecular formula: C182H285N51O52S. Mole weight: 4051.64. | |
| Amyloid β-Protein Fragment 35-25 | Amyloid β-Protein Fragment 35-25, the reverse sequence of Aβ 25-35, serves as an inactive control. Synonyms: H-Met-Leu-Gly-Ile-Ile-Ala-Gly-Lys-Asn-Ser-Gly-OH; Amyloid β-Protein (35-25); β-Amyloid (35-25); L-methionyl-L-leucyl-glycyl-L-isoleucyl-L-isoleucyl-L-alanyl-glycyl-L-lysyl-L-asparagyl-L-seryl-glycine. Grades: ≥95%. CAS No. 147740-73-6. Molecular formula: C45H81N13O14S. Mole weight: 1060.27. | |
| Amyloid Bri Protein Precursor277 (89-106) | Synonyms: H-Cys-Gly-Ile-Lys-Tyr-Ile-Lys-Asp-Asp-Val-Ile-Leu-Asn-Glu-Pro-Ser-Ala-Asp-OH; L-cysteinyl-glycyl-L-isoleucyl-L-lysyl-L-tyrosyl-L-isoleucyl-L-lysyl-L-alpha-aspartyl-L-alpha-aspartyl-L-valyl-L-isoleucyl-L-leucyl-L-asparagyl-L-alpha-glutamyl-L-prolyl-L-seryl-L-alanyl-L-aspartic acid. Grades: ≥95% by HPLC. CAS No. 1802078-21-2. Molecular formula: C87H141N21O30S. Mole weight: 1993.24. | |
| Amyloid Precursor Protein ? (304-612), Secreted human | >90% (SDS-PAGE), recombinant, expressed in E. coli (N-terminal histidine tagged), buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Amyloid Precursor Protein N-Terminal Peptide | lyophilized powder. Group: Fluorescence/luminescence spectroscopy. | |
| Amyloid Precursor Protein ?, Secreted human | ?85% (SDS-PAGE), recombinant, expressed in E. coli (N-terminal histidine tagged), solution, sterile; 0.2 ?m filtered. Group: Fluorescence/luminescence spectroscopy. | |
| Amyloid Precursor Protein ?, Secreted human | >90% (SDS-PAGE), recombinant, expressed in E. coli (N-terminal histidine tagged), buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Amyloid ? Protein Fragment 1-40 | ?90% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| Amyloid ?-Protein Fragment 1-40 amide trifluoroacetate salt | ?95% (HPLC), lyophilized powder. Group: Fluorescence/luminescence spectroscopy. | |
| Amyloid ?-Protein Fragment 17-28 | ?90% (HPLC), lyophilized powder. Group: Fluorescence/luminescence spectroscopy. | |
| Amyloid ?-Protein Fragment 17-40 | ?87% (HPLC), lyophilized powder. Group: Fluorescence/luminescence spectroscopy. | |
| Amyloid ?-Protein Fragment 22-35 | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Amyloid ?-Protein Fragment 25-35 | ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Amyloid ?-Protein Fragment 35-25 | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Amyloid ?-Protein Fragment 40-1 | ?90% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Amyloid Protein Non-A? Component | ?80% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| 5-FAM-Amyloid β-Protein (1-40) | 5-FAM-Amyloid β-Protein (1-40) is a FAM-fluorescentially labeled β-amyloid (1-40) peptide (λex = 492 nm; λem= 518 nm). Synonyms: 5-FAM-Aβ40;β-Amyloid (1-40), FAM-labeled; Fluorescein-5-carbonyl-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH. Grades: ≥95%. CAS No. 1678416-08-4. Molecular formula: C215H305N53O64S. Mole weight: 4688.17. | |
| 5-FAM-Amyloid β-Protein (1-40)-Lys(εAhx-biotinyl) amide | 5-FAM-Amyloid β-Protein (1-40)-Lys(εAhx-biotinyl) amide is fluorescent-labeled Aβ40, which may be immobilized. Synonyms: 5-FAM-beta-Amyloid (1-40)-Lys(biotin LC) amide; Fluorescein-5-carbonyl-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Lys(εAhx-biotinyl)-NH2. Grades: ≥90%. Molecular formula: C237H343N59O67S2. Mole weight: 5154.82. | |
| 5-FAM-Amyloid β-Protein (1-42) | Synonyms: 5-FAM-Aβ42; Fluorescein-5-carbonyl-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH; N6-[(3',6'-Dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)carbonyl]-L-alpha-aspartyl-L-alanyl-L-alpha-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-alpha-aspartyl-L-serylglycyl-L-tyrosyl-L-alpha-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-valylglycyl-L-seryl-L-asparaginyl-L-lysylglycyl-L-alanyl-L-isoleucyl-L-isoleucylglycyl-L-leucyl-L-methionyl-L-valylglycylglycyl-L-valyl-L-valyl-L-isoleucyl-L-alanine. Grades: ≥95%. CAS No. 1802087-78-0. Molecular formula: C224H321N55O66S. Mole weight: 4872.41. | |
| 5-FAM-Amyloid β-Protein (1-42) (scrambled) | 5-FAM-Amyloid β-Protein (1-42) (scrambled) is a fluorescent dye-labeled inactive control for amyloid β42. Synonyms: 5-FAM-Beta-Amyloid (1-42), Scrambled, Human; Fluorescein-5-carbonyl-Ala-Ile-Ala-Glu-Gly-Asp-Ser-His-Val-Leu-Lys-Glu-Gly-Ala-Tyr-Met-Glu-Ile-Phe-Asp-Val-Gln-Gly-His-Val-Phe-Gly-Gly-Lys-Ile-Phe-Arg-Val-Val-Asp-Leu-Gly-Ser-His-Asn-Val-Ala-OH. Grades: ≥90%. Molecular formula: C224H321N55O66S. Mole weight: 4872.41. | |
| 5-TAMRA-Amyloid β-Protein (1-40) | Anderson and Webb were able to verify by transmission electron microscopy that the N-terminal labeling of Aβ40 with TAMRA and other fluorescent dyes could not prevent the formation of protofibrils and amyloid fibrils of various widths. Synonyms: 5-TAMRA-Aβ40; 5-TAMRA-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH. Grades: ≥95%. CAS No. 1802087-81-5. Molecular formula: C219H315N55O62S. Mole weight: 4742.31. | |
| 7-Methoxycoumarin-4-acetyl-[Asn670,Leu671]-Amyloid ?/A4 Precursor Protein 770 (667-676)-(2,4-dinitrophenyl)Lys-Arg-Arg Amide | ?96% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| 7-Methoxycoumarin-4-acetyl-[Asn670, Leu671]-Amyloid ?/A4 Precursor Protein 770 Fragment 667-674-(2,4-dinitrophenol)Dap | ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| 7-Methoxycoumarin-4-acetyl-[Asn670, Leu671]-Amyloid ?/A4 Precursor Protein 770 Fragment 667-676-(2,4-dinitrophenyl)Lys-Arg-Arg amide | ?90% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| 7-Methoxycoumarin-4-acetyl-[Asn670, Leu671]-Amyloid ?/A4 Precursor Protein 770 Fragment 669-674-(2,4-dinitrophenyl)Lys trifluoroacetate salt | ?96% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Abz-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (669-674)-EDDnp | Abz-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (669-674)-EDDnp is an intramolecularly quenched fluorescent substrate with the ortho-aminobenzoyl (Abz)/N-(2,4-dinitrophenyl)ethylenediamine (EDDnp) groups as the donor/acceptor pair. It corresponds to the Swedish-mutated (JMV2236) β-amyloid precursor protein (βAPP) sequence, which is targeted by β-secretase BACE (β-site APP-cleaving activity). It is more selectively cleaved by BACE1 and BACE2 than by cathepsin D, a disintegrin and metalloprotease 10 (ADAM10), tumor necrosis α-converting enzyme (TACE), presenilin-1 (PS1), or presenilin-2 (PS2). Synonyms: JMV2236; L-α-Glutamine, N-(2-aminobenzoyl)-L-valyl-L-asparaginyl-L-leucyl-L-α-aspartyl-L-alanyl-N-[2-[(2,4-dinitrophenyl)amino]ethyl]-; N-(2-Aminobenzoyl)-L-valyl-L-asparaginyl-L-leucyl-L-α-aspartyl-L-alanyl-N-{2-[(2,4-dinitrophenyl)amino]ethyl}-L-α-glutamine. Grades: ≥95%. CAS No. 1007306-20-8. Molecular formula: C42H58N12O16. Mole weight: 986.99. | |
| Acetyl-Amyloid β-Protein (1-6) amide | Experiments using sub-peptides of Aβ42 show that the epitope identified by antibody A8 is located in the 1-6 region of A&beta. Synonyms: Ac-DAEFRH-NH2; L-Histidinamide, N-acetyl-L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-L-arginyl-; N-acetyl-L-alpha-aspartyl-L-alanyl-L-alpha-glutamyl-L-phenylalanyl-L-arginyl-L-histidinamide. Grades: ≥95%. CAS No. 903883-22-7. Molecular formula: C35H50N12O11. Mole weight: 814.85. | |
| Acetyl-Amyloid ?-Protein Fragment 15-20 Amide | ?97% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| Acetyl-amyloid ss-protein(15-20)amide | Acetyl-amyloid ss-protein(15-20)amide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BETA-AMYLOID LIGAND;AMYLOID BETA-PROTEIN ACETYL-FRAGMENT 15-20 AMIDE;AC-QKLVFF;AC-AMYLOID BETA-PROTEIN (15-20) AMIDE;ACETYL-BETA-AMYLOID (15-20);ACETYL-AMYLOID BETA-PROTEIN (15-20) AMIDE;AC-GLN-LYS-LEU-VAL-PHE-PHE-NH2;AC-GLN-LYS-LEU-VAL-PHE-PHE-OH. Product Category: Heterocyclic Organic Compound. CAS No. 189064-06-0. Molecular formula: C42H62N8O9. Mole weight: 822.99. Purity: 0.96. IUPACName: (2S)-2-acetamido-N-[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]pentanediamide. Product ID: ACM189064060. Alfa Chemistry ISO 9001:2015 Certified. | |
| Acetyl-(N-Me-Leu17,N-Me-Phe19)-Amyloid β-Protein (16-20) amide | Acetyl-(N-Me-Leu17,N-Me-Phe19)-Amyloid β-Protein (16-20) amide is a membrane-permeable inhibitor of Aβ (1-40) fibrillogenesis. Synonyms: Ac-Lys-(NMe)Leu-Val-(NMe)Phe-Phe-NH2; N2-Acetyl-L-lysyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-phenylalanyl-L-phenylalaninamide; L-Phenylalaninamide, N2-acetyl-L-lysyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-phenylalanyl-. Grades: ≥95%. CAS No. 461640-33-5. Molecular formula: C39H59N7O6. Mole weight: 721.94. | |
| Acetyl-(Pro18,Asp21)-Amyloid β-Protein (17-21) amide | Acetyl-(Pro18,Asp21)-Amyloid β-Protein (17-21) amide is an analog of product H-4876 with small chemical modifications which enhance its stability against proteolytic degradation. It is a β-sheet breaker peptide that crosses the blood-brain barrier faster than most known proteins and peptides selectively absorbed by the brain, so it is assumed that the peptide is specifically transported to the brain. Synonyms: iAβ5p; Ac-LPFFD-NH2; N-acetyl-L-leucyl-L-prolyl-L-phenylalanyl-L-phenylalanyl-L-isoasparagine; L-α-Asparagine, N-acetyl-L-leucyl-L-prolyl-L-phenylalanyl-L-phenylalanyl-. Grades: ≥95%. CAS No. 339990-02-2. Molecular formula: C35H46N6O8. Mole weight: 678.78. | |
| Aftin-4 (N6-Methyl-(R)-roscovitine, Amyloid-beta Forty-Two Inducer 4) | Roscovitine-related purine with no activity on CDKs (used as control for roscovitine). Selectively and potently increases production of extracellular Abeta42 and decreases production of extracellular Abeta38 in cultured cells. Extracellular Abeta40 levels remain stable. Intracellular levels of these amyloids appear to remain stable. Alzheimer's Disease (AD) accelerator that interacts with VDAC1, prohibitin and mitofilin, possibly interfering with subcellular compartmentalization and lipid rafts properties, shifting gamma-secretase activity toward Abeta42 generation. Induces a reversible mitochondrial phenotype reminiscent of the one observed in AD brains. Tool to detect inhibitors of Aftin-induced actions (potential anti-AD compounds). Binds pyridoxal kinase. Group: Biochemicals. Grades: Highly Purified. CAS No. 866893-90-5. Pack Sizes: 1mg, 5mg, 25mg. US Biological Life Sciences. |  Worldwide |
| Aftin-5 ((2R)-2-[[9-Isopropyl-6-(N-methylanilino)purin-2-yl]amino]butan-1-ol, Amyloidbeta Forty-Two Inducer 5) | Roscovitine-related purine with no activity on CDKs (used as control for roscovitine). Selectively and potently increases production of extracellular Ab42 and decreases production of extracellular Ab38 in cultured cells. Extracellular Ab40 levels remain stable. Intracellular levels of these amyloids appear to remain stable. Alzheimer's Disease (AD) accelerator that interacts with VDAC1, prohibitin and mitofilin, possibly interfering with subcellular compartmentalization and lipid rafts properties, shifting gamma-secretase activity toward Ab42 generation. Induces a reversible mitochondrial phenotype reminiscent of the one observed in AD brains. Tool to detect inhibitors of Aftin-induced actions (potential anti-AD compounds). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| [Ala28]-Amyloid ? 25-35 | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| α-Amyloid Precursor Protein Modulator | α-Amyloid Precursor Protein Modulator is a cell-permeable benzolactam derived PKC activator (Ki = 11.9 nM for PKCα) that efficiently enhances non-amyloidogenic α-processing of amyloid precursor protein (APP) even at 100 nM in human fibroblast AG06848. α-Amyloid Precursor Protein Modulator displays a marked loss of tumor promoting activity. Applications: A cell-permeable benzolactam derived pkc activator. Group: Coenzymes. Synonyms: (2S,5S)-(E,E)-8-(5-(4-(Trifluoromethyl)phenyl)-2,4-pentadienoylamino)benzolactam; PKC Activator V. CAS No. 497259-23-1. Purity: ≥95%. Mole weight: 501.55. Form: Solid. (2S,5S)-(E,E)-8-(5-(4-(Trifluoromethyl)phenyl)-2,4-pentadienoylamino)benzolactam; PKC Activator V; α-Amyloid Precursor Protein Modulator; 497259-23-1. Cat No: COEC-109. |  |
| α-Amyloid Precursor Protein Modulator | α-Amyloid Precursor Protein Modulator is a cell-permeable protein kinase C (PKC) activator. It was shown to induce differentiation of hESCs into Pdx-1 expressing pancreatic progenitor cells. Synonyms: TPPB; alpha-APP Modulator; (2E,4E)-N-[(2S,5S)-5-(hydroxymethyl)-1-methyl-3-oxo-2-propan-2-yl-2,4,5,6-tetrahydro-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]penta-2,4-dienamide. Grades: >98%. CAS No. 497259-23-1. Molecular formula: C27H30F3N3O3. Mole weight: 501.55. | |
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