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Androstane-3-a, 17b-diol 3-O-b-D-glucuronide-D3 is a pivotal compound in the biomedical field assuming a fundamental function in the exploration of the metabolic processes, pharmacokinetics and therapeutic impacting of androstenediol as well as comparable steroids. In biological samples, it predominantly serves as a reference standard or analytical instrument to precisely assess the levels of androstane-3-a,17b-diol 3-O-b-D-glucuronide-D3, thereby significantly facilitating drug development endeavors and furthering disease research. Synonyms: androstanediol-17g;(2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[[(3R,5S,8R,9S,10S,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]oxy]oxane-2-carboxylic acid; 5alpha-androstane-3alpha,17beta-diol 17-glucuronide; 5alpha-androstane-3alpha,17beta-diol 17-glucuronoside; 5alpha-androstane-3alpha,17beta-diol 17-glucosiduronic acid; 3alpha-hydroxy-5alpha-androstan-17beta-yl beta-D-glucopyranosiduronic acid; (3alpha,5alpha,17beta)-3-hydroxyandrostan-17-yl beta-D-glucopyranosiduronic acid; androstane -3,17- diol 17- glucuronide ; Androstane- 3alpha,17 beta-diol glucuronide. CAS No. 148616-25-5. Molecular formula: C25H37O8D3. Mole weight: 471.60.
1, 1'-[ (2b, 3a, 5a, 16b, 17b)-3, 17-Bis (acetyloxy)androstane-2, 16-diyl]bis (1-methylpiperidinium) dibromide. Group: Biochemicals. Alternative Names: Pancuronium bromide; Mioblock; NA 97. Grades: Highly Purified. CAS No. 15500-66-0. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C35H60Br2N2O4. US Biological Life Sciences.
Worldwide
11-Hydroxy-3-oxo-androstane-17-carboxylic Acid
11-hydroxy-3-oxo-androstane-17-carboxylic Acids an intermediate in the synthesis of 11 β-Hydroxy-3-oxo-androsta-1,4-diene-17 β-carboxylic Acid which is itself an impurity of Prednisolone (P703740), which is a synthetic glucocorticoid, a derivative of cortisol, and can be used to treat a variety of inflammatory and auto-immune conditions. It is also the active metabolite of the drug prednisone. Group: Biochemicals. Grades: Highly Purified. CAS No. 1620520-25-3. Pack Sizes: 25mg, 50mg. Molecular Formula: C20H30O4. US Biological Life Sciences.
Worldwide
17α-Methyl-5α-androstane-2 β,3α,17 β)-triol
17α-Methyl-5α-androstane-2 β,3α,17 β)-triol is a derivative of Madol (M108000, which is an anabolic steroid recently identified to be misused as a doping agent. The potency of Madol (DMT) to transactivate androgen receptor (AR) dependent reporter gene expression was two times lower as compared to dihydrotestosterone (DHT). Group: Biochemicals. Grades: Highly Purified. CAS No. 1375064-29-1. Pack Sizes: 10mg, 25mg. Molecular Formula: C20H34O3, Molecular Weight: 322.48. US Biological Life Sciences.
Worldwide
17α-Methyl-5α-androstane-2 β,3α,17 β)-triol-d3
17α-Methyl-5α-androstane-2 β,3α,17 β)-triol-d3 is the isotope labelled analog of 17α-Methyl-5α-androstane-2 β,3α,17 β)-triol. 17α-Methyl-5α-androstane-2 β,3α,17 β)-triol is a derivative of Madol (M108000, which is an anabolic steroid recently identified to be misused as a doping agent. The potency of Madol (DMT) to transactivate androgen receptor (AR) dependent reporter gene expression was two times lower as compared to dihydrotestosterone (DHT). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C20H31D3O3, Molecular Weight: 325.5. US Biological Life Sciences.
Worldwide
17α-Methyl-5α-androstane-3 β,6α,17 β-triol
17α-Methyl-5α-androstane-3 β,6α,17 β-triol is an intermediate in the synthesis of 6-α-Hydroxy Stanozolol (H953580). 6-α-Hydroxy Stanozolol is a metabolite of Stanozolol (S684500), an androgenic/anabolic steroid used for treating conditions such as anaemia and hereditary angioedema. Group: Biochemicals. Grades: Highly Purified. CAS No. 89267-40-3. Pack Sizes: 25mg, 50mg. Molecular Formula: C20H34O3, Molecular Weight: 322.48. US Biological Life Sciences.
Worldwide
17 β-Methyl-5 β-androstane-3α,17α-diol
17 β-Methyl-5 β-androstane-3α,17α-diol is derived from 17 β-Methyl epi-Testosterone (M326405), which is a metabolite of 17α-Methyltestosterone (M326400). Group: Biochemicals. Grades: Highly Purified. CAS No. 88729-26-4. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C20H34O2, Molecular Weight: 306.48. US Biological Life Sciences.
Worldwide
17 β-Methyl-5 β-androstane-3α,17α-diol-d5
17 β-Methyl-5 β-androstane-3α,17α-diol-d5 is the isotope labelled analog of 17 β-Methyl-5 β-androstane-3α,17α-diol. 17 β-Methyl-5 β-androstane-3α,17α-diol is derived from 17 β-Methyl epi-Testosterone (M326405), which is a metabolite of 17α-Methyltestosterone (M326400). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C20H29D5O2, Molecular Weight: 311.51. US Biological Life Sciences.
Worldwide
17-Methyl-5α-androstane-3α,17 β-diol
17-Methyl-5α-androstane-3α,17 β-diol is an anabolic androgenic steroid (AAS) and a metabolite of 17α-Methyl Testosterone (M326400). Group: Biochemicals. Grades: Highly Purified. CAS No. 641-82-7. Pack Sizes: 25mg, 250mg. Molecular Formula: C20H34O2, Molecular Weight: 306.48. US Biological Life Sciences.
Worldwide
17-Methyl-5α-androstane-3α,17 β-diol-d3
17-Methyl-5α-androstane-3α,17 β-diol-d3 is the isotope labelled analog of 17-Methyl-5α-androstane-3α,17 β-diol (M287845); an anabolic androgenic steroid (AAS) and metabolite of 17α-Methyl Testosterone (M326400). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C20H31D3O2, Molecular Weight: 309.5. US Biological Life Sciences.
Worldwide
17-Methyl-5α-androstane-3 β,16α,17 β-triol
A metabolite of 17α-Methyltestosterone (M326400). Group: Biochemicals. Grades: Highly Purified. CAS No. 188525-77-1. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C20H34O3, Molecular Weight: 322.48. US Biological Life Sciences.
Worldwide
17-Methyl-5α-androstane-3 β,16α,17 β-triol-d3
A labelled metabolite of 17α-Methyltestosterone (M326400). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C20H31D3O3, Molecular Weight: 325.5. US Biological Life Sciences.
Worldwide
17-Methyl-5α-androstane-3 β,16 β,17 β-triol
A metabolite of 17α-Methyltestosterone (M326400). Group: Biochemicals. Grades: Highly Purified. CAS No. 38863-74-0. Pack Sizes: 25mg, 250mg. Molecular Formula: C20H34O3, Molecular Weight: 322.48. US Biological Life Sciences.
Worldwide
17-Methyl-5α-androstane-3 β,16 β,17 β-triol-d3
A labelled metabolite of 17α-Methyltestosterone (M326400). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C20H31D3O3, Molecular Weight: 325.5. US Biological Life Sciences.
Worldwide
17-Methyl-5 β-androstane-3α,17 β-diol
17-Methyl-5 β-androstane-3α,17 β-diol is found in urine and is a metabolite of 17α-Methyltestosterone (M326400), an androgenic agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 641-84-9. Pack Sizes: 50mg, 500mg. Molecular Formula: C20H34O2, Molecular Weight: 306.48. US Biological Life Sciences.
Worldwide
17-Methyl-5 β-androstane-3 β,16 β,17 β-triol
A metabolite of 17α-Methyltestosterone (M326400). Group: Biochemicals. Grades: Highly Purified. CAS No. 923572-10-5. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C20H34O3, Molecular Weight: 322.48. US Biological Life Sciences.
Worldwide
17-Methyl-5 β-androstane-3 β,16 β,17 β-triol-d3
A labelled metabolite of 17α-Methyltestosterone (M326400). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C20H31D3O3, Molecular Weight: 325.5. US Biological Life Sciences.
An intermediate in the preparation of Dacuronium Bromide (D102700), a metabolite of neuromuscular blocking agent Pancuronium (P178500). Group: Biochemicals. Alternative Names: 2α, 3α:16α, 17α-Bisepoxy-5α-androstan-17 β-ol acetate; 2α, 3α:16α, 17α-Diepoxy-17-acetoxy-5α-androstane. Grades: Highly Purified. CAS No. 50588-22-2. Pack Sizes: 100mg. US Biological Life Sciences.
Intermediate in the preparation of Dacuronium Bromide (D102700), a metabolite of neuromuscular blocking agent Pancuronium (P178500) with much weaker activity. Group: Biochemicals. Alternative Names: (2 β, 3α, 5α, 16 β,17 β)-2,16-Di-1-piperidinyl-androstane-3,17-diol 3-Acetate. Grades: Highly Purified. CAS No. 53357-31-6. Pack Sizes: 10mg. US Biological Life Sciences.
This compound is used in the synthesis of the neuromuscular blocking agent rocuronium bromide. Group: Biochemicals. Alternative Names: 2 β-(4-Morpholinyl)-16 β-(1-pyrrolidinyl)-5α-androstane-3α,17 β-diol; (2 β, 3α, 5α, 16 β,17 β)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstan-3,17-diol; Desacetyl Desallyl Rocuronium. Grades: Highly Purified. CAS No. 119302-20-4. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
3α-hydroxy-5β-androstane-17-one 3α-dehydrogenase
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. This enzyme participates in androgen and estrogen metabolism. Group: Enzymes. Synonyms: etiocholanolone 3α-dehydrogenase; etiocholanolone 3α-dehydrogenase; 3α-hydroxy-5β-steroid dehydrogenase. Enzyme Commission Number: EC 1.1.1.152. CAS No. 37250-77-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0057; 3α-hydroxy-5β-androstane-17-one 3α-dehydrogenase; EC 1.1.1.152; 37250-77-4; etiocholanolone 3α-dehydrogenase; etiocholanolone 3α-dehydrogenase; 3α-hydroxy-5β-steroid dehydrogenase. Cat No: EXWM-0057.
A Cortisol metabolite. Group: Biochemicals. Alternative Names: 5α-Androstane-3,11,17-trione. Grades: Highly Purified. CAS No. 1482-70-8. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
5-Alpha-androstane-alpha-nor-2,17-dione
Heterocyclic Organic Compound. Alternative Names: 5 A NDROSTANE-A-NOR-2,17-DIONE; 5-ALPHA-ANDROSTANE-ALPHA-NOR-2,17-DIONE; 5ANDROSTANE-A-NOR-2,17-DIONE. CAS No. 1032-12-8. Molecular formula: C18H26O2. Mole weight: 274.398. Purity: 0.96. IUPACName: A-nor-5α-androstan-2,17-dione. Catalog: ACM1032128.
5 β,19-Cycloandrostane-3,17-dione-d2
Labeled hydroaromatic steroid hormone. Group: Biochemicals. Alternative Names: 5,19-Cyclo-5 β-androstane-3,17-dione-d2; 5,19-Cycloandrostane-3,17-dione-19,19-d2. Grades: Highly Purified. CAS No. 71995-57-8. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
5β-Androstane-3α,17β-diol 3-Glucuronide
5β-Androstane-3α,17β-diol 3-Glucuronide can be used in biological study of steroid glucuronides of the seminal vesicle as olfactory stimuli in African catfish, Clarias gariepinus. Synonyms: Androstane β-D-Glucopyranosiduronic Acid deriv.; (3α,?5β,?17β)?-17-Hydroxyandrostan-3-yl β-D-Glucopyranosiduronic Acid. Grades: 97%. CAS No. 114761-91-0. Molecular formula: C25H40O8. Mole weight: 468.58.
7a,17a-Dimethyl-5b-androstane-3a-17b-diol
7a,17a-Dimethyl-5b-androstane-3a-17b-diol. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg, 25mg, 50mg. US Biological Life Sciences.
7-a,17-a-Dimethyl-5-b-androstane-3-a,17-b-diol glucuronide is a prominent glucuronide conjugate of 7-a,17-a-Dimethyl-5-b-androstane-3-a,17-b-diol, acting as a catalyst in the exploration of androgenic steroid metabolism, bioavailability and elimination. Molecular formula: C27H43O8.Na. Mole weight: 518.62.
7α,17α-Dimethyl-5-androstane-3α,17-diol
7α,17α-Dimethyl-5-androstane-3α,17-diol. Uses: For analytical and research use. Group: Impurity standards. CAS No. 13611-10-4. Molecular Formula: C21H36O2. Mole Weight: 320.52. Catalog: APB13611104.
7-b,17-a-Dimethyl-5-b-androstane-3-a,17-b-diol glucuronide is a vital compound playing a crucial role in the research of hormone-related disorders, particularly those involving impaired androgen metabolism. Molecular formula: C27H43O8.Na. Mole weight: 518.62.
17-Hydroxy-6-methylene-pregna-1,4-diene-3,20-dione is a steroid that can be used in the synthetic preparation of Androstane derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 1204325-01-8. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C22H28O3, Molecular Weight: 340.46. US Biological Life Sciences.
Worldwide
1α-Methyl-5α-androstan-3α,17 β-diol
1α-Methyl-5α-androstan-3α,17 β-diol is an metabolite of anabolic androgenic steroid, testosterone (T155000). 1α-Methyl-5α-androstan-3α,17 β-diol is also the methylated analogue of 5α-Androstane-3 β,17 β-diol (A637526). Group: Biochemicals. Grades: Highly Purified. CAS No. 4349-94-4. Pack Sizes: 5mg, 10mg. Molecular Formula: C20H34O2. US Biological Life Sciences.
Worldwide
1α-Methyl-5α-androstan-3α,17 β-diol-d3
Isotope labelled 1α-Methyl-5α-androstan-3α,17 β-diol (M287920) is an metabolite of anabolic androgenic steroid, testosterone (T155000). 1α-Methyl-5α-androstan-3α,17 β-diol is also the methylated analogue of 5α-Androstane-3 β,17 β-diol (A637526). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C20H31D3O2, Molecular Weight: 309.5. US Biological Life Sciences.
Worldwide
2,3-Seco-5-androstan-17-one-2,3-dicarboxylic acid
Heterocyclic Organic Compound. Alternative Names: 17-Oxo-2,3-seco-5-androstan-2,3-dioic acid;2,3-Seco-5-androstan-17-one-2,3-dicarboxylic acid;2,3-SECO-5A-ANDROSTANE-17-ONE-2,3-DIOIC ACID. CAS No. 1165-38-4. Catalog: ACM1165384.
2-Carboxy mestanolone methyl ester
2-Carboxy mestanolone methyl ester. Group: Biochemicals. Alternative Names: (5a,17b)-17-Hydroxy-17-methyl-3-oxo-androstane-2-carboxylic acid methyl ester. Grades: Highly Purified. CAS No. 145553-00-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C22H34O4. US Biological Life Sciences.
(2S) -3-Bromo-N-[4-cyano-3- (trifluoromethyl) phenyl]-2-hydroxy-2-methyl-propanamide is a reactant used in the preparation of hydroxy (phenylthio) propionanilides as affinity ligands for the androstane receptor. Group: Biochemicals. Alternative Names: (S) -3-Bromo-N-[4-cyano-3- (trifluoromethyl) phenyl]-2-hydroxy-2-methyl-propanamide. Grades: Highly Purified. CAS No. 113181-02-5. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
(3a,5a,17Z)-Pregn-17(20)-en-3-ol
(3a,5a,17Z)-Pregn-17(20)-en-3-ol. Group: Biochemicals. Alternative Names: (17Z)-17-Ethylidene-3a-hydroxy-5a-androstane; (3a,5a,17Z)-Pregn-17(20)-en-3-ol. Grades: Highly Purified. CAS No. 68199-34-8. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C21H34O. US Biological Life Sciences.
Worldwide
(3α, 5α, 17Z)-Pregn-17(20)-en-3-ol
(3α, 5α, 17Z)-Pregn-17(20)-en-3-ol. Group: Biochemicals. Alternative Names: (17Z)-17-Ethylidene-3α-hydroxy-5α-androstane; (3α, 5α, 17Z)-Pregn-17(20)-en-3-ol. Grades: Highly Purified. CAS No. 68199-34-8. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
3α-Hydroxysteroid Dehydrogenase from B. choshinensis, Recombinant
In enzymology, a 3alpha-hydroxysteroid dehydrogenase (B-specific) (EC 1.1.1.50) is an enzyme that catalyzes the chemical reaction: androsterone + NAD(P)+ <-> 5alpha-androstane-3,17-dione + NAD(P)H + H+. The 3 substRates of this enzyme are androsterone, NAD+, and NADP+, whereas its 4 products are 5alpha-androstane-3,17-dione, NADH, NADPH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor, more specifically it is part of the group of hydroxysteroid dehydrogenases. Group: Enzymes. Synonyms: hydroxyprostaglandin dehydrogenase; 3α-hydroxysteroid oxidoreductase; sterognost 3α; 3α-hydroxysteroid dehydrogenas. Enzyme Commission Number: EC 1.1.1.50. CAS No. 9028-56-2. 3α-Hydroxysteroid Dehydrogenase. Mole weight: ca. 41 kDa. Activity: > 30 U/mg lyophilizate. Stability: stable at 37°C for at least four weeks. Appearance: White lyophilizate. Storage: at -20°C. Source: B. choshinensis. Species: B. choshinensis. hydroxyprostaglandin dehydrogenase; 3α-hydroxysteroid oxidoreductase; sterognost 3α; 3α-hydroxysteroid dehydrogenase (B-specific); 3α-hydroxysteroid 3-dehydrogenase (B-specific); 3α-hydroxysteroid:NAD(P)+ 3-oxidoreductase (B-specific); EC 1.1.1.50. Cat No: DIA-413.
3α-Hydroxysteroid Dehydrogenase, Recombinant
In enzymology, a 3alpha-hydroxysteroid dehydrogenase (B-specific) (EC 1.1.1.50) is an enzyme that catalyzes the chemical reaction: androsterone + NAD (P)+ ? 5alpha-androstane-3,17-dione + NAD (P)H + H+. The 3 substRates of this enzyme are androsterone, NAD+, and NADP+, whereas its 4 products are 5alpha-androstane-3,17-dione, NADH, NADPH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor, more specifically it is part of the group of hydroxysteroid dehydrogenases. Applications: Bile acid is one of the substrates of 3α-hydroxy steroiddehydrogenase. 3α-hydroxy ste...3-dehydrogenase (B-specific); 3α-hydroxysteroid:NAD (P)+ 3-oxidoreductase (B-specific); EC 1.1.1.50. Enzyme Commission Number: EC 1.1.1.50. Purity: 90% (SDS-PAGE test). Mole weight: About 28 kDa (SDS-PAGE detection). Activity: About 50U/mg powder. Appearance: White powder, lyophilized. Storage: 4°C, store at -20°C for long-term preservation. Form: Freeze dried powder. hydroxyprostaglandin dehydrogenase; 3α-hydroxysteroid oxidoreductase; sterognost 3α; 3α-hydroxysteroid dehydrogenase (B-specific); 3α-hydroxysteroid 3-dehydrogenase (B-specific); 3α-hydroxysteroid:NAD (P)+ 3-oxidoreductase (B-specific); EC 1.1.1.50. Cat No: NATE-1138.
3α(or 20β)-hydroxysteroid dehydrogenase
The 3α-hydroxy group or 20β-hydroxy group of pregnane and androstane steroids can act as donor. Group: Enzymes. Synonyms: cortisone reductase; (R)-20-hydroxysteroid dehydrogenase; dehydrogenase, 20β-hydroxy steroid; Δ4-3-ketosteroid hydrogenase; 20β-hydroxysteroid dehydrogenase; 3α,20β-hydroxysteroid:NAD+-oxidoreductase; NADH-20β-hydroxysteroid dehydrogenase; 20β-HSD. Enzyme Commission Number: EC 1.1.1.53. CAS No. 9028-42-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0338; 3α(or 20β)-hydroxysteroid dehydrogenase; EC 1.1.1.53; 9028-42-6; cortisone reductase; (R)-20-hydroxysteroid dehydrogenase; dehydrogenase, 20β-hydroxy steroid; Δ4-3-ketosteroid hydrogenase; 20β-hydroxysteroid dehydrogenase; 3α,20β-hydroxysteroid:NAD+-oxidoreductase; NADH-20β-hydroxysteroid dehydrogenase; 20β-HSD. Cat No: EXWM-0338.
3b-tert-Butyldimethylsilyloxy epiandrosterone
3b-tert-Butyldimethylsilyloxy epiandrosterone. Group: Biochemicals. Alternative Names: (3b, 5a) -3-[[ (1, 1-Dimethylethyl) dimethylsilyl]oxy]-androstan-17-one; 3b-[ (tert-Butyldimethylsilyl) oxy]-17-oxo-5a-androstane. Grades: Highly Purified. CAS No. 57711-44-1. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C25H44O2Si. US Biological Life Sciences.
Worldwide
3(or 17)α-hydroxysteroid dehydrogenase
Acts on the 3α-hydroxy group of androgens of the 5α-androstane series; and also, more slowly, on the 17α-hydroxy group of both androgenic and estrogenic substrates (cf. EC 1.1.1.51 3(or 17)β-hydroxysteroid dehydrogenase). Group: Enzymes. Synonyms: 3(17)α-hydroxysteroid dehydrogenase. Enzyme Commission Number: EC 1.1.1.209. CAS No. 83294-77-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0113; 3(or 17)α-hydroxysteroid dehydrogenase; EC 1.1.1.209; 83294-77-3; 3(17)α-hydroxysteroid dehydrogenase. Cat No: EXWM-0113.
Steroidal Compounds. Alternative Names: 11-KETOANDROSTERONE;5-ALPHA-ANDROSTAN-3-ALPHA-OL-11,17-DIONE;3-ALPHA-HYDROXY-5-ALPHA-ANDROSTANE-11,17-DIONE;Androstane-11,17-dione, 3-hydroxy-, (3alpha,5alpha)-;3α-Hydroxy-5α-androstane-11,17-dione, 5α-Androstan-3α-ol-11,17-dione;3α-Hydroxy-5α-androstan. CAS No. 1231-82-9. Molecular formula: C19H28O3. Mole weight: 304.42. Appearance: White Solid. Purity: 95%+. IUPACName: 11-Oxo Androsterone. Density: 1.152g/cm³. Catalog: ACM1231829.
5α-Androstan-3 β-ol
An Androstane metabolite. Group: Biochemicals. Alternative Names: (3 β,5α)-. Grades: Highly Purified. CAS No. 1224-92-6. Pack Sizes: 100mg. US Biological Life Sciences.
Cholanoic Acid is an impurity of Ursodeoxycholic Acid, which is used as an anticholelithogenic. Synonyms: 5β-Cholan-24-oic acid; 5β-Cholanic acid; 5β-Cholanoic acid; (5β,17β)-γ-Methyl-androstane-17-butanoic Acid; L 596205-0; NSC 18161; Ursocholanic Acid. Grades: > 95%. CAS No. 546-18-9. Molecular formula: C24H40O2. Mole weight: 360.59.
CITCO, an imidazothiazole derivative, is a selective Constitutive androstane receptor (CAR) agonist. CITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC 50 of 49?nM over pregnane X receptor (PXR) , and no activity on other nuclear receptors [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 338404-52-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103244.
CITCO
CITCO is a constitutive androstane receptor (CAR) agonist (EC50 = 49 nM), inducing nuclear translocation of human CAR in hepatocytes, followed by increased expression of CAR-regulated genes, including several cytochrome P450 isoforms. Uses: Constitutive androstane receptor (car) agonist. Synonyms: 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime. Grades: ≥98%. CAS No. 338404-52-7. Molecular formula: C19H12Cl3N3OS. Mole weight: 436.74.
Δ4-Abiraterone
Δ4-Abiraterone (D4A) is an active metabolite of the CYP17A1 inhibitor abiraterone (Item No. 9002768).1 D4A is an androgen receptor antagonist (IC50 = 5.3 nM) that reduces expression of the androgen receptor target genes PSA, TMPRSS2, and FKBP5 in LNCaP, LAPC4, and C4-2 cell lines. It inhibits the cytochrome P450 (CYP) isoform CYP17A1 by 66.5% when used at a concentration of 1 nM. D4A (10 μM) also blocks SRD5A conversion of Δ4-androstenedione to 5α-androstanedione in LAPC4 cells. In vivo, D4A delays tumor progression in a VCaP mouse xenograft model and increases progression-free survival in a C4-2 mouse xenograft model. Synonyms: CB 7627; D4A. Grades: ≥98%. CAS No. 154229-21-7. Molecular formula: C24H29NO. Mole weight: 347.49.
The reduced product of Finasteride : a mechanism-based inhibitor of human prostate and skin steroid 5α-reductase. It forms an enzyme-bound NADP-dihydrofinasteride adduct during this inhibitory process. Group: Biochemicals. Alternative Names: (4aR, 4bS, 6aS, 7S, 9aS, 9bS, 11aR) -N- (1, 1-Dimethylethyl) hexadecahydro-4a, 6a-dimethyl-2-oxo-1H-indeno[5, 4-f]quinoline-7-carboxamide; Dihydroproscar; (5α,17 β)-N-(1,1-Dimethylethyl)-3-oxo-4-azaandrostane-17-carboxamide; [4aR-(4aα,4b β, 6aα, 7α, 9a β,9bα,11a β ) ]-N- (1, 1-Dimethylethyl) hexadecahydro-4a, 6a-dimethyl-2-oxo-1H-indeno[5, 4-f]quinoline-7-carboxamide; 1,2-Dihydrofinasteride; 3-Oxo-4-aza-5α-androstan-17 β-carboxylic acid N-(tert-butyl)amide; N-(tert-Butyl)-3-oxo-4-aza-5α-androstane-17 β-carboxamide. Grades: Highly Purified. CAS No. 98319-24-5. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Epitestosterone-d3 Glucuronide
Epitestosterone-d3 Glucuronide. Group: Biochemicals. Alternative Names: (17α)-3-oxoandrost-4-en-17-y-d3 β-D-Glucopyranosiduronic Acid; Androstane, β-D-Glucopyranosiduronic-d3 Acid Deriv.; Epi-Testosterone-d3 Glucosiduronate; Epitestosterone-d3 Glucuronoside. Grades: Highly Purified. CAS No. 1101127-63-2. Pack Sizes: 1mg. Molecular Formula: C25H33D3O8, Molecular Weight: 467.57. US Biological Life Sciences.
Worldwide
Epitestosterone Glucuronide
Epitestosterone Glucuronide. Group: Biochemicals. Alternative Names: (17α)-3-oxoandrost-4-en-17-yl β-D-Glucopyranosiduronic Acid; Androstane, β-D-Glucopyranosiduronic Acid Deriv.; Epi-Testosterone Glucosiduronate; Epitestosterone Glucuronoside. Grades: Highly Purified. CAS No. 16996-33-1. Pack Sizes: 2.5mg. Molecular Formula: C25H36O8, Molecular Weight: 464.55. US Biological Life Sciences.
Worldwide
HE-3235
HE3235 is an orally bioavailable adrenal steroid analogue with potential antineoplastic activity. Androstane steroid HE3235 appears to bind the androgen receptor (AR), down-regulating anti-apoptotic genes, such as Bcl-2, while increasing the expression of pro-apoptotic genes, such as caspases. In vitro and in vivo studies indicate that this agent inhibits androstenediol-dependent LNCaP cell tumor growth. In addition, HE3235 may potentiate chemotherapeutic agents by down-regulating ABCG2, the gene encoding the multi-drug resistant (MDR) protein MDR2. Synonyms: HE 3235; HE3235; Apoptone; (17R)-5alpha-Pregnane-20-yne-3alpha,17-diol. CAS No. 183387-50-0. Molecular formula: C21H32O2. Mole weight: 316.48.
Isobutylparaben
Isobutylparaben (Isobutyl 4-hydroxybenzoate) is a constitutive androstane receptor (CAR) activator. Isobutylparaben has a broad-spectrum antimicrobial activity and widely used in personal care products and cosmetics [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Isobutyl-P-Hydroxybenzoate. CAS No. 4247-2-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W015026.
Istaroxime
Istaroxime, also called as PST 2744, is an inhibitor of sodium-potassium ATPase that exhibits the unique property of increasing SERCA2a activity. This has been demonstrated in sarcoplasmic reticulum vesicles from normal guinea pigs, where istaroxime incre. Synonyms: PST-2744; PST 2744; PST2744; Istaroxime; (3E,5S,8R,9S,10R,13S,14S)-3-(2-aminoethoxyimino)-10,13-dimethyl-1,2,4,5,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-6,17-dione3-((2-aminoethoxy)imino)androstane-6,17-dione3-((2-aminoethoxy)imino)androstane-6,17-dione hydrochlorideIstaroxi. CAS No. 203737-93-3. Molecular formula: C21H32N2O3. Mole weight: 360.49.
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