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| Product | Description | |
|---|---|---|
| Ansamycin | 25mg Pack Size. Group: Antibiotics, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C46H62N4O11. CAS No. 72559-06-9. Prepack ID 11006783-25mg. Molecular Weight 847. See USA prepack pricing. |  |
| Rifabutin (Rifamycin XIV, Ansamycin) | An antibacterial. Group: Biochemicals. Alternative Names: Rifamycin XIV, Ansamycin. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. |  Worldwide |
| 17-AG | An orally bioavailable formulation of the ansamycin derivative 17-amino-17-demethoxygeldanamycin (17-AG) with potential antineoplastic activity. Oral Hsp90 inhibitor IPI-493 binds to and inhibits Hsp90, which may result the in growth inhibition in sensitive tumor cell populations. Synonyms: 17 AG; 17AG; 17-AG; IPI493; IPI 493; IPI-493; NSC 255109; NSC255109; NSC-255109; 17-Aminogeldanamycin; 17-Amino Geldanamycin; 17-Aminodemethoxygeldanamycin; 17-Amino-17-demethoxygeldanamycin. Grade: >98%. CAS No. 64202-81-9. Molecular formula: C28H39N3O8. Mole weight: 545.62. |  |
| 3-Amino-4-fluoro-5-hydroxybenzoic Acid | 3-Amino-4-fluoro-5-hydroxybenzoic Acid is used for study of novel ansamycins produced by genetically engineered Streptomyces hygroscopicus geldanus strains. Group: Biochemicals. Grades: Highly Purified. CAS No. 1025127-41-6. Pack Sizes: 10mg, 25mg. Molecular Formula: C7H6FNO3, Molecular Weight: 171.13. US Biological Life Sciences. | Worldwide |
| Ansamitocin PDM-3 | Ansamitocin PDM-3 is an ansamycin antibiotic isolated from Actinosynnema pretiosum, and exhibits antitumor activity. Synonyms: Ansamitocin P-3; N-Demethylansamitocin P 3; N-Demethylansamitocin P-3. CAS No. 77353-69-6. Molecular formula: C31H41ClN2O9. Mole weight: 621.1. | |
| Damavaricin D | Damavaricin D is an ansamycin antibiotic isolated from the Streptovaricin complex produced by Streptomyces spectabilis. It is the biosynthetic precursor of Streptomycin D, and also has anti-Gram-positive bacteria, anti-Gram-negative bacteria and anti-fungal effects. CAS No. 59556-95-5. Molecular formula: C37H47NO12. Mole weight: 697.77. | |
| Geldanamycin | Geldanamycin is a benzoquinone ansamycin antibiotic that inhibits heat shock protein 90 (HSP90). Geldanamycin has been shown to promote survival of neural stem cells from oxidative stress via inhibition of HSP90. It displays potent antineoplastic properties and inhibits myeloma cell growth. Uses: Antibiotics, antineoplastic. Synonyms: geldanomycin; NSC 122750; [(3R,5S,6R,7S,8E,10S,11S,12Z,14E)-6-hydroxy-5,11,21-trimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate. Grade: >98%. CAS No. 30562-34-6. Molecular formula: C29H40N2O9. Mole weight: 560.64. | |
| Geldanamycin (Streptomyces hygroscopicus) 98+% | Geldanamycin is benzoquinone ansamycin antibiotic isolated from Streptomyces hygroscopicus. A potent antitumor 1 and potent inhibitor of p60c-crc tyrosine kinase, erb B2,2 EGF receptor tyrosine kinase and non-receptor tyrosine kinases. 3, Geldanamycin binds specifically and inhibits the chaperone protein Hsp90.2. Group: Biochemicals. Alternative Names: 9, 13-Dihydroxy-8, 14, 19-trimethoxy-4, 10, 12, 16-tetramethyl-2-azabicyclo[16. 3. 1]docosa-4, 6, 10, 18, 21-pentaene-3, 20, 22-trione 9-Carbamate; (+)-Geldanamycin; NSC 122750; NSC 212518; BRN1633093. Grades: Highly Purified. CAS No. 30562-34-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Halomicin A | It is produced by the strain of Micromonospora halophytica var. nigra. It's an ansamycin antibiotic. Halomicin complex has activity against gram-positive and gram-negative bacteria (individual). Synonyms: SP-30-A; 4-Deoxy-4-[3-hydroxy-2-(1-hydroxyethyl)-1-pyrrolidinyl]rifamycin; Rifamycin, 4-deoxy-4-(3-hydroxy-2-(1-hydroxyethyl)-1-pyrrolidinyl)-. CAS No. 56411-51-9. Molecular formula: C43H58N2O13. Mole weight: 810.93. | |
| Halomicin B | It is produced by the strain of Micromonospora halophytica var. nigra. It's an ansamycin antibiotic. Halomicin complex has activity against gram-positive and gram-negative bacteria (individual). Synonyms: Rifamycin, 4-deoxy-4-(2-(1-hydroxyethyl)-1-pyrrolidinyl)-, (4(2R(1S)))-. CAS No. 54356-09-1. Molecular formula: C43H58N2O12. Mole weight: 794.92. | |
| Halomicin C | It is produced by the strain of Micromonospora halophytica var. nigra. It's an ansamycin antibiotic. Halomicin complex has activity against gram-positive and gram-negative bacteria (individual). Synonyms: 4-Deoxy-20-hydroxy-4-[2-(1-hydroxyethyl)-1-pyrrolidinyl]rifamycin. CAS No. 64419-06-3. Molecular formula: C43H58N2O13. Mole weight: 810.93. | |
| Halomicin D | It is produced by the strain of Micromonospora halophytica var. nigra. It's an ansamycin antibiotic. Halomicin complex has activity against gram-positive and gram-negative bacteria (individual). Synonyms: N,2-Didehydro-1,4-dideoxy-1,2-dihydro-4-[(2R)-2-[(S)-1-hydroxyethyl]-1-pyrrolidinyl]-1-oxorifamycin. CAS No. 56413-94-6. Molecular formula: C43H56N2O12. Mole weight: 792.91. | |
| Herbimycin A | Herbimycin A, an ansamycin antibiotic , acts as a Src family kinase inhibitor. Herbimycin A binds to the SH domain and inhibits the activity of p60 v-src and p210 BCR-ABL Herbimycin A inhibits Hsp90 and impairs recovery from heat shock. Herbimycin A exhibits antiangiogenic activity in endothelial cells in vitro. Uses: Scientific research. Group: Natural products. CAS No. 70563-58-5. Pack Sizes: 1 mg; 2.5 mg; 500 μg; 100 μg. Product ID: HY-108486. |  |
| Herbimycin A | Herbimycin A is produced by the strain of Streptomyces hygroscopicus. It is an ansamycin antibiotic that acts as a Src family kinase inhibitor and Hsp90 inhibitor. It has herbicidal effect on most monocotyledons and dicotyledons, inhibits the activity of tobacco Mosaic virus (TMV), HeLa cells and Ehrlich cells. Uses: Enzyme inhibitors. Synonyms: Herbimycin; Antibiotic Tan 420F; NSC 305978. Grade: >98%. CAS No. 70563-58-5. Molecular formula: C30H42N2O9. Mole weight: 574.67. | |
| Herbimycin A (Antibiotic TAN 420F, (15R)-17-Demethoxy-15-methoxy-11-O-methyl-geldanamycin) | Benzoquinone ansamycin antibiotic. Herbicidal compound. Potent, selective, irreversible and cell permeable protein tyrosine kinase inhibitor. Inhibitor of v-Src, Yes, Fps, Ros, Bcr-Abl and ErbB oncogene products. Antitumor compound. Antiangiogenic. Inhibits NF-kappaB activation and phosphorylation of phospholipase C-gamma1. Inhibitor of heat shock protein 90 (Hsp90). Binds Hsp90 and destabilizes client proteins leading to their ubiquitination and proteasomal degradation. Increases the sensitivity of certain cancer cells to chemotherapeutic agents. Neuroprotective. Antiparasitic, antischistosomal agent. Antiviral. Increase microtubules sensitivity to cold in plants. Group: Biochemicals. Grades: Highly Purified. CAS No. 70563-58-5. Pack Sizes: 100ug, 1mg. Molecular Formula: C30H42N2O9. US Biological Life Sciences. | Worldwide |
| Herbimycin A (Herbimycin, Antibiotic TAN 420F) | Herbimycin A is the major analogue of a complex of benzoquinone ansamycin antibiotics isolated from a Streptomyces hygroscopicus. Herbimycin A inhibits the 90-kD heat-shock protein (Hsp90) which provides essential chaperone support to various signal transduction molecules, including including certain steroid hormone receptors and select kinases. Herbimycin has also been shown to inhibit protein tyrosine kinase and angiogensis. Group: Biochemicals. Alternative Names: Herbimycin, Antibiotic TAN 420F. Grades: Highly Purified. CAS No. 70563-58-5. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Herbimycin B | It is produced by the strain of Streptomyces hygroscopicus. It is an ansamycin antibiotic that acts as a Src family kinase inhibitor. It has herbicidal effect on most monocotyledons and dicotyledons, inhibits the activity of tobacco Mosaic virus (TMV), HeLa cells and Ehrlich cells. Synonyms: Geldanamycin, 17-demethoxy-. Grade: ≥95%. CAS No. 76207-83-5. Molecular formula: C28H38N2O8. Mole weight: 530.61. | |
| Herbimycin C | It is produced by the strain of Streptomyces hygroscopicus. It is an ansamycin antibiotic that acts as a Src family kinase inhibitor. It has herbicidal effect on most monocotyledons and dicotyledons, inhibits the activity of tobacco Mosaic virus (TMV), HeLa cells and Ehrlich cells. Synonyms: Geldanamycin, 17-demethoxy-15-methoxy-, (15R)-. Grade: >98% by HPLC. CAS No. 91700-92-4. Molecular formula: C29H40N2O9. Mole weight: 560.64. | |
| Naphthomycin B (2-Demethylnaphthomycin A) | Ansamycin antibiotic. Antibacterial and antifungal. Group: Biochemicals. Grades: Highly Purified. CAS No. 86825-88-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Rifabutin | Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-N-ISOBUTYLSPIROPIPERIDYLRIFAMYCIN S;RIFABUTIN;RIFABUTINE;1,4-dihydro-1-deoxy-1',4-didehydro-5'-(2-methylpropyl)-1-oxo-rifamycinxi;1,4-dihydro-1-deoxy-1',4-didehydro-5'-(2-methylpropyl)-1-oxorifamycinxiv;1',4-Didehydro-1-deoxy-1,4-dihydro-5'-(2-methylpropyl)-1-oxo-;4-deoxo-3,4-(2-spiro(n-isobutyl-4-piperidyl)-2,5-dihydro-1h-imidazo)-rifamyc;Ansamycin. Product Category: Inhibitors. Appearance: Solid. CAS No. 72559-06-9. Molecular formula: C46H62N4O11. Mole weight: 847. Purity: 0.992. Canonical SMILES: C[C@H]1/C=C/C=C(C)\C(/N=C2C(O)=C3C(C4=C(O[C@@](O/C=C/[C@H](OC)[C@@H](C)[C@@H](OC(C)=O)[C@H](C)[C@H](O)[C@H](C)[C@H]1O)(C)C4=O)C(C)=C3O)=C5C/2=NC6(CCN(CC(C)C)CC6)N5)=O. Product ID: ACM72559069. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Rifabutin | Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ansamycin; LM-427. CAS No. 72559-06-9. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-17025. | |
| Rifabutin-[d7] | An isotope labelled Rifabutin. Rifabutin is an antibiotic used to prevent and treat Mycobacterium avium and tuberculosis infection. Synonyms: 1',4-Didehydro-1-deoxy-1,4-dihydro-5'-(2-methylpropyl)-1-oxorifamycin XIV-d7; Ansatipine-d7; Ansamycin-d7; Antibiotic LM 427-d7; LM 427-d7; Mycobutin-d7. Grade: 95% by HPLC; 98% atom D. Molecular formula: C46H55D7N4O11. Mole weight: 854.04. | |
| Rifamycin sodium | Rifamycin sodium (Rifamycin SV monosodium) belongs to the family of ansamycin antibiotics and has been isolated from the fermentation of A. mediterranei or its mutants. Rifamycin sodium displays a broad spectrum of antibiotic activity against Gram-positive and, to a lesser extent, Gram-negative bacteria [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Rifamycin SV sodium. CAS No. 14897-39-3. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-B1907. | |
| Streptovaricin U | Streptovaricin U is an acyclic ansamycin produced by Str. spectabilis. CAS No. 74200-47-8. Molecular formula: C36H49NO10. Mole weight: 655.77. | |
| TMC-135A | TMC-135A is a triene-ansamycin antibiotic produced by Streptomyces sp. TC 1190. It is cytotoxic to HCT-116, SK-BR-3, HeLa S3, WiDr, HT29 and HL-60 with IC50 values of 0.07, 0.88, 0.11, 0.20, 0.15 and 0.05 μmol/L, respectively. Synonyms: TMC-135 A. Molecular formula: C39H49N3O8S. Mole weight: 719.9. | |
| TMC-135B | TMC-135B is a triene-ansamycin antibiotic produced by Streptomyces sp. TC 1190. It is cytotoxic to HCT-116, SK-BR-3, HeLa S3, WiDr, HT29 and HL-60. Synonyms: TMC-135 B. Molecular formula: C39H49N3O8S. Mole weight: 719.9. | |
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