Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
1-(2-Chloro-4-nitrophenyl)ethanone is used in the preparation of Propiconazole (P770100) as haptens in manufacture of antibodies with hybridomas for immunoassay. Group: Biochemicals. Grades: Highly Purified. CAS No. 67818-41-1. Pack Sizes: 500mg, 1g. Molecular Formula: C8H6ClNO3, Molecular Weight: 199.59. US Biological Life Sciences.
Worldwide
1,2-Dimethyl-1,4,5,6-tetrahydropyrimidine
1,2-Dimethyl-1,4,5,6-tetrahydropyrimidine is a reagent used in the synthesis of pyrantel derivatives with nematocidal activity. Also used as a reactant in the preparation of hapten antibodies that evoke terpenoid cyclization. Group: Biochemicals. Grades: Highly Purified. CAS No. 4271-96-9. Pack Sizes: 1g, 5g. Molecular Formula: C6H12N2. US Biological Life Sciences.
Worldwide
1,4-Benzoquinone Monoguanylhydrazone
1,4-Benzoquinone monoguanylhydrazone is a hydrazone derivative of p-Benzoquinone (B206580), an aromatic compound that is used to couple antigens and antibodies to marker substances such as erythrocytes. Group: Biochemicals. Grades: Highly Purified. CAS No. 7316-92-9. Pack Sizes: 100mg, 250mg. Molecular Formula: C7H8N4O, Molecular Weight: 164.16. US Biological Life Sciences.
1- (Difluoromethyl) -4- [ [ (1, 1-dimethylethyl) dimethylsilyl] oxy] benzene is an analog of 4-(Difluoromethyl)-phenol (D447525), a reagent used in the design and synthesis of haptens to elicit catalytic antibodies with phosphatase activity against nerve agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 2055829-99-5. Pack Sizes: 500mg, 1g. Molecular Formula: C13H20F2OSi, Molecular Weight: 258.38. US Biological Life Sciences.
Worldwide
2',3'-cGAMP sodium salt
2',3'-cGAMP sodium is an endogenous cGAMP in mammalian cells. 2',3'-cGAMP sodium binds to STING with a high affinity and is a potent inducer of interferon-&beta. 2',3'-cGAMP is an effective adjuvant that boosts the production of antigen-specific antibodies and T cell responses in mice. Synonyms: Cyclic [G(2',5')pA(3',5')p] sodium; cyclic GMP-AMP sodium; 2',3'-cyclic GMP-AMP sodium; 2',3'-Cyclic guanosine monophosphate-adenosine monophosphate sodium salt. Grades: 95%. CAS No. 2734858-36-5. Molecular formula: C20H22N10Na2O13P2. Mole weight: 718.38.
2,5-Dihydro-2,5-dioxo- β-sulfo-1H-pyrrole-1-butanoic Acid 1-(2,5-Dioxo-1-pyrrolidinyl) Ester is used in the synthesis of hydrophilic heterobifunctional crosslinkers for conjugation of antibodies with highly cytotoxic agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 1193111-53-3. Pack Sizes: 1mg. Molecular Formula: C12H12N2O9S, Molecular Weight: 360.3. US Biological Life Sciences.
2-Acetonyl-1,3,4,6-tetra-O-acetyl-2-deoxy-b-D-galactopyranoside: an indispensable chemical compound that plays a vital role in the synthesis and glycosylation of biologically significant molecules like proteins and antibodies. Its versatile usage extends to the analysis of complex carbohydrate structures and their intricate interplay in various biological processes - making it an eminent research tool for carbohydrate chemists and biochemists alike.
2-Amino-N-(2-aminoethyl)benzamide Hydrochloride
2-Amino-N-(2-aminoethyl)benzamide hydrochloride is used in biological studies for immunization with recombinantly expressed glycan antigens from Schistosoma mansoni which induces glycan-specific antibodies against parasite. Group: Biochemicals. Grades: Highly Purified. CAS No. 1175543-63-1. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H14ClN3O, Molecular Weight: 215.68. US Biological Life Sciences.
Worldwide
3'-(6-TAMRA) CPG 1000
3'-(6-TAMRA) CPG 1000 is a specialized product that plays a pivotal role in biomedicine to treat various diseases like cancer, rheumatoid arthritis, and asthma. It is used in research pertaining to the development of vaccines, therapeutic antibodies, and gene therapy extensively.
3-Aminopropyltriethoxysilane
3-Aminopropyltriethoxysilane (APTES) acts as a strong glue to immobilize biomolecules such as antibodies and enzymes to silicon and silicon derivatives such as silicon nitride (Si 3 N 4 )) on. 3-Aminopropyltriethoxysilane also acts as a spacer, providing biomolecules with more spatial freedom during immobilization for higher specific activity. 3-Aminopropyltriethoxysilane can form a more stable, sensitive, and highly biocompatible bioanalytical platform by immobilizing biomolecules onto some solid materials, electrode materials, nanomaterials, and nanocomposites [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: γ-Aminopropyltriethoxysilane; APTES. CAS No. 919-30-2. Pack Sizes: 10 g; 50 g; 100 g. Product ID: HY-D0175.
(3-Aminopropyl)trimethoxysilane
97%. Uses: Aptms can be multilayered on siox substrates by a layer by layer self assembly. aptms has also been used as a silane coupling agent on silver nanoparticles.aptms is used for the synthesis of gold nano-bipyramids which can be used as substrates for c-reactive protein (crp) antibodies that were detected by localized surface plasmon resonance(lspr). mesoporous silica matrix can be incorporated with aptms for the removal of chromium (cr) from waste water. it can also be used to silanize magnetic iron oxide nanoparticles(mionps) for the separation of cross-linked enzyme aggregations (cleas) from the reaction medium. it may be coated on tio2 to improve the power conversion efficiency (pce) as a critical parameter to assess the overall performance of heterojunction perovskite solar cells (pscs). Group: Saltself-assembly materials. Alternative Names: 3-(Trimethoxysilyl)propylamine. CAS No. 13822-56-5. Pack Sizes: 5 mL/100 mL/500 mL. Product ID: 3-trimethoxysilylpropan-1-amine. Molecular formula: 179.29 g/mol. Mole weight: C6H17NO3Si. CO[Si](CCCN)(OC)OC. InChI=1S/C6H17NO3Si/c1-8-11(9-2, 10-3)6-4-5-7/h4-7H2, 1-3H3. SJECZPVISLOESU-UHFFFAOYSA-N. 0.97.
3-Bromo-L-tyrosine
3-Bromo-L-tyrosine is used in the preparation and synthesis of polyclonal antibodies that work against brominated protein related allergic responses and afflictions. Also effective in asthma control and prediction in children. Synonyms: H-Tyr(3-Br)-OH; H-Phe(3-Br,4-OH)-OH; 3-Bromo-4-hydroxy-L-phenylalanine. Grades: 98%. CAS No. 38739-13-8. Molecular formula: C9H10BrNO3. Mole weight: 260.08.
3-Tri-N-butylstannyl-phenylisothiocyanate
A compound used potentially for the radioiodination of monoclonal antibodies. Used in Antibody labelling. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
4-Bromobenzoic Acid Methyl Ester
4-Bromobenzoic Acid Methyl Ester is halogenated benzoate used as a reagent in organic synthesis. 4-Bromobenzoic Acid Methyl Ester can be used to stimulate microbial dechlorination of PCBs. 4-Bromobenzoic Acid Methyl Ester is also used in the preparation of stable radioiodinating reagent to label monoclonal antibodies for radiotherapy of cancer. Group: Biochemicals. Alternative Names: 1-Bromo-4- (methoxycarbonyl) benzene; 4-Methoxycarbonyl-1-bromobenzene; 4-Methoxycarbonylphenyl Bromide; Methyl 4-Bromobenzoate; Methyl p-Bromobenzoate; NSC 9392; p-Bromobenzoic Acid Methyl Ester. Grades: Highly Purified. CAS No. 619-42-1. Pack Sizes: 10g. US Biological Life Sciences.
Worldwide
4-Hydroxybutyryl-L-carnitine-13C3
4-Hydroxybutyryl-L-carnitine-13C3 is carbon-13 labeled 4-Hydroxybutyryl-L-carnitine (H824652) is an aryl carnitine, which is an important metabolite used as a diagnostic tool for detecting inherited metabolic disorders. Antibodies can be raised against L-carnitine and other carnitine-related compounds to measure the quantity of L-carnitine in biological samples and serum. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C813C3H21NO5, Molecular Weight: 250.27. US Biological Life Sciences.
Worldwide
5(6)-FITC
5(6)-FITC (Fluorescein 5(6)-isothiocyanate) is an amine-reactive derivative of a fluorescent dye, characterized by high absorbance and excellent fluorescence quantum yield. The isothiocyanate group of FITC can react with various functional groups on proteins, including amines, thiols, imidazoles, tyrosines and carbonyls, enabling the labeling of proteins such as antibodies and lectins. 5(6)-FITC has a wide range of applications, including flow cytometry, immunofluorescence, protease assays and conjugation. The maximum excitation/emission wavelengths are 492/518 nm [1] [2] [3] [4]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Fluorescein 5(6)-isothiocyanate; Fluorescein isothiocyanate 5- and 6- isomers. CAS No. 27072-45-3. Pack Sizes: 100 mg; 500 mg. Product ID: HY-15941.
5'-Amino-Modifier C12-PDA
5'-Amino-Modifier C12-PDA, a biomedical research reagent, is adept at oligonucleotide and DNA modification. Its versatility manifests in facilitating the conjugation of multiple molecules such as antibodies and fluorescent dyes, henceforth enabling diagnostic and therapeutic interventions. Synonyms: 12-(N²-methyl-N¹-phthalimidyl)-dodecyl-1-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C30H51N4O4P. Mole weight: 562.7.
5-Bromo-3-indolyl phosphate p-toluidine salt
5-Bromo-3-indolyl phosphate p-toluidine salt, an imperative compound extensively employed in the biomedical sector, assumes a pivotal role as a substrate for alkaline phosphatase. This facilitates the accurate identification of phosphatase activities and enzyme-labeled antibodies, thereby enabling precise detection. With its widespread application in immunohistochemistry experiments, this product seamlessly discerns specific antigens or proteins within tissues or cells. Synonyms: Lapis phosphate. CAS No. 80008-69-1. Molecular formula: C8H6BrNO4P.C7H10N. Mole weight: 399.18.
5-Bromo-5-nitro-1,3-dioxane
5-bromo-5-nitro-1,3-Dioxane is an antimicrobial compound that is effective against Gram-positive and Gram-negative bacteria and fungi, including yeast.1 Its mode of action occurs via the oxidation of essential protein thiols causing inhibition of enzyme activity and subsequent inhibition of microbial growth.1 This compound has been used as a preservative for biological molecules and solutions such as antibodies and antisera. Group: Biochemicals. Grades: Highly Purified. CAS No. 30007-47-7. Pack Sizes: 50g, 100g, 250g, 500g, 1Kg. Molecular Formula: C?H?BrNO?, Molecular Weight: 212. US Biological Life Sciences.
Worldwide
5-Bromo-UTP
5-Bromo-UTP is commonly used to label RNA through being incorporated into RNA for the detection with anti-5-Bromo-UTP antibodies and for the random-mutation introduction. Synonyms: (5Br-UTP); 5-Bromo-uridine-5'-triphosphate, Sodium salt; 5-BrUTP. Grades: ≥ 95% by HPLC. Molecular formula: C9H14N2O15P3Br (free acid). Mole weight: 563.03 (free acid).
6-a-Sialyl-N-acetyllactosamine-PAA-biotin
6-a-Sialyl-N-acetyllactosamine-PAA-biotin is a groundbreaking and indispensable compound, facilitating the study of glycoproteins and glycolipids' sialylation processes. This extraordinary compound manifests as a meticulously engineered ligand, exhibiting exceptional selectivity towards lectins and antibodies that essentially target sialic acid residues. Synonyms: Neu5Ac-a-2-6-Gal-b-1-4-GlcNAc-O(CH2)3-PAA-(CH2)6-biotin 6-SLN-biotin.
6-Azidohexanoic acid sulfo-NHS ester
6-Azidohexanoic Acid Sulfo-NHS Ester is an azido-containing building block that can be used to derivatize primary amines with an azido group via a stable amide bond. 6-Azidohexanoic Acid Sulfo-NHS Ester is used to modify proteins, antibodies, and other amine-containing biopolymers in aqueous media. Grades: ≥ 95% (HPLC). Molecular formula: C11H14N4NaO7S. Mole weight: 356.28.
6-O-Sulfated Lewisa
6-O-Sulfated Lewisa, a carbohydrate antigen prone to cancer cell overexpression, has been identified as a possible target for cancer immunotherapy medications like monoclonal antibodies. This perplexing and bursty substance has been a key subject of exploration for treating various cancers, including all too common and fatal forms such as ovarian, pancreatic, and breast cancer. As an added benefit, this complex carbohydrate antigen also presents itself as an effective diagnostic tool for detecting cancer cells. Grades: ≥95%. Molecular formula: C20H34NNaO18S. Mole weight: 631.53.
ATTO-488 is a fluorescent probe commonly used in biomedical research to visualize cellular structures and monitor biological processes in living cells. Its excitation and emission spectra are well-suited for live-cell imaging studies, and it has been used to track the localization and trafficking of proteins and organelles. Additionally, ATTO-488 can be conjugated to antibodies and used for flow cytometry and immunoassays, making it a valuable tool for drug discovery and disease diagnosis. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-2',5'-bisphosphate, labeled with ATTO 488, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C41H50N10O19P2S2 (free acid). Mole weight: 1112.22 (free acid).
8-[(6-Amino)hexyl]-amino-ATP - ATTO-620
ATTO-620 is a highly effective fluorescent dye known for its meticulous labeling of biomolecules comprising a number of previously insurmountable substances such as proteins, nucleotides, and antibodies in the field of biomedical research. This extraordinary dye radiates emissions solely in the near-infrared spectrum championing its relevance in immunohistochemistry as well as in vivo imaging research. Additionally, this product has played a vital role in studying life-altering diseases such as cancer, Alzheimer's disease, and infectious diseases, igniting a new wave of scientific research. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-5'-triphosphate, labeled with ATTO 620, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H30N7O13P3- ATTO 620 (free acid). Mole weight: 1114.37 (free acid).
9-(2-Carboxy-2-cyanovinyl)julolidine
9-(2-Carboxy-2-cyanovinyl)julolidine is a fluorescent molecular rotor. 9-(2-Carboxy-2-cyanovinyl)julolidine can be used to bind to IgG and Fab, and preparing antibodies [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 142978-18-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-D0054.
AADvac-1
AADvac-1 is an active vaccine designed to raise antibodies against pathological tau protein (the primary constituent of neurofibrillary pathology in AD). These antibodies are expected to prevent tau protein from aggregating, to facilitate the removal of tau protein aggregates and prevent the spreading of pathology, slowing or halting the progress of the disease. Synonyms: AADvac-1; Alzheimer's disease vaccine - Axon Neuroscience; Axon peptide 108 conjugated to KLH; Axon peptide 108 coupled to KLH. CAS No. 2307465-24-1.
Abagovomab
Abagovomab (Anti-Human CA-125 Recombinant Antibody) is a murine monoclonal anti-idiotypic antibody, against the tumor-associated antigen, CA-125. Abagovomab is generated by a mouse hybridoma, can imitate the human TAA, CA-125. Abagovomab can elicit humoral and cellular immune responses against ovarian cancer (oc) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human CA-125 Recombinant Antibody. CAS No. 792921-10-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P99276.
Abatacept
Abatacept (CTLA4lg) is a soluble fusion protein consisting of the extra-cellular domain of human CTLA4 and a fragment of the Fc portion of human IgG1 (hinge and CH2 and 3 domains) [1]. Abatacept is a selective T-cell co-stimulation modulator and a protein agent for the autoimmune diseases [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CTLA4lg; BMS-188667. CAS No. 332348-12-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-108829.
Abatacept (powder)
Abatacept (CTLA4lg; BMS-188667) powder is a soluble fusion protein consisting of the extra-cellular domain of human CTLA4 and a fragment of the Fc portion of human IgG1 (hinge and CH2 and 3 domains). Abatacept powder is a selective T-cell co-stimulation modulator and a protein agent for the autoimmune diseases [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CTLA4lg (powder); BMS-188667 (powder). CAS No. 332348-12-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-108829A.
Abciximab
Abciximab (C7E3), a chimeric mouse/human monoclonal antibody fragment, is a glycoprotein (GP) IIb/IIIa inhibitor. Abciximab inhibits platelet aggregation and leucocyte adhesion by binding to the glycoprotein IIb/IIIa, vitronectin and Mac-1 receptors [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: C7E3. CAS No. 143653-53-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9934.
Abelacimab
Abelacimab (MAA868) is a fully human IgG1 monoclonal antibody that binds with high affinity to the catalytic structural domain of FXI and locks it in the zymogen conformation, thereby preventing its activation by FXIIa or thrombin. Abelacimab can be used in thromboembolic disease studies [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MAA868. CAS No. 2098724-83-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99415.
Abiprubart
Abiprubart is an anti- CD40 human IgG4 κ monoclonal antibody [1]. Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2765071-95-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990726.
Abituzumab
Abituzumab (DI17E6) is a humanised anti- integrin αV monoclonal antibody (IgG2 type). Abituzumab effectively reduces the phosphorylation of FAK , Akt and ERK. Abituzumab can be used in cancer research, particularly in prostate cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: EMD 525797; DI17E6. CAS No. 1105038-73-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99183.
Abrilumab
Abrilumab is a fully human monoclonal antibody directed against α4β7. Abrilumab selectively binds the α4β7 integrin heterodimer. Abrilumab can be used for the research of inflammatory bowel disease (IBD) [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1342290-43-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99184.
Acapatamab
Acapatamab (AMG-160) is an anti- CD3E/FOLH1 monoclonal antibody [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AMG-160. CAS No. 2314491-93-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99418.
Acasunlimab
Acasunlimab (GEN1046) is a bispecific antibody (bsAb) targeting PD-L1 and 4-1BB. Acasunlimab enhances T-cell and NK-cell function through conditional 4-1BB stimulation while constitutively blocking the PD-1/PD-L1 inhibitory axis. Acasunlimab can be used in research of cancer [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: GEN1046. CAS No. 2253937-12-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99419.
ACI-35
ACI-35 is a liposome-based vaccine designed to stimulate a patient's immune system to produce antibodies against the misfolded and phosphorylated pathogenic forms of Tau protein. Synonyms: Anti-pTau vaccine - AC Immune.
ACT017
ACT017 is a Fab fragment of humanized anti- GPVI monoclonal antibody. ACT017 inhibits collagen-induced platelet aggregation. ACT017 has the potential for the research of acute ischemic stroke [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2101829-58-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99644.
Actoxumab
Actoxumab (Anti-C. difficile Toxin A Recombinant Antibody) is a antitoxin antibody against C. difficile toxin A by neutralizing TcdA. Actoxumab prevents both the damage to the gut wall and the inflammatory response, which are associated with C. difficile. Actoxumab has synergy effect with Bezlotoxumab (HY-P9929) targeting TcdB [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-C. difficile Toxin A Recombinant Antibody. CAS No. 1245634-25-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99277.
Adakitug
Adakitug (BMS-986253) is a CHO-expressed human antibody targeting CXCL8/IL-8. Adakitug contains huIgG1 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 144.94 kDa. The isotype control for Adakitug can refer to Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BMS-986253; HuMax-IL-8. CAS No. 2231258-73-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990598.
Adalimumab
Adalimumab is a human monoclonal IgG1 antibody targeting tumour necrosis factor?α ( TNF-α ). Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human TNF-alpha, Human Antibody. CAS No. 331731-18-1. Pack Sizes: 1 mg; 5 mg; 25 mg; 50 mg. Product ID: HY-P9908.
Adebrelimab
Adebrelimab (SHR-1316) is a humanized IgG4 monoclonal PD-L1 ( PD-1/PD-L1 ) antibody. Adebrelimab has promising antitumor activity in solid tumors including extensive-stage small-cell lung cancer (SCLC) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SHR-1316. CAS No. 2247114-85-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99422.
Adecatumumab
Adecatumumab (Anti-Human EPCAM Recombinant Antibody; MT201) is a full human monoclonal antibody of the IgG1 isotype, targeting human EpCAM. Adecatumumab is expressed in almost all adenocarcinomas, and its activity is not dependent of K-Ras status [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MT 201; Anti-Human EPCAM Recombinant Antibody. CAS No. 503605-66-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99278.
Adintrevimab
Adintrevimab (ADG 20) is a human IgG1 monoclonal SARS-CoV ( SARS-CoV ) antibody. Adintrevimab inhibits SARS-CoV-2 variants and other SARS-like coronaviruses with pandemic potential [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ADG 20. CAS No. 2516243-54-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99423.
Aducanumab
Aducanumab (BIIB037) is a human monoclonal antibody that selectively targets aggregated amyloid-beta (Aβ). Aducanumab shows brain penetration, and can be used for Alzheimer's disease (AD) research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BIIB037. CAS No. 1384260-65-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9967.
AF488 azide
AF488 is a fluorescent dye. AF488 is a fluorophore pH-insensitive over a broad pH range (from 4 to 10). It has an absorption maximum at 495 nm and an emission maximum at 519 nm in the green spectrum region. The dye is hydrophilic and can be used to introduce the fluorescent label into various molecules, including proteins and antibodies. Conjugates of molecules with AF488 have high brightness and photostability and are commonly used in flow cytometry and microscopy. This allows the detection of biological objects with high sensitivity at a longer imaging time.,AF488 azide interacts with alkynyl derivatives of biomolecules in Click Chemistry reactions either in the presence of copper (I) catalyst (with terminal alkynes) or without catalyst (with cyclooctynes), leading to the formation of stable adducts. Grades: NMR 1H, HPLC-MS (95%). CAS No. 1679326-36-3 (with azidohexyl group). Molecular formula: C36H56N8O10S2. Mole weight: 825.01.
AF594 activated ester, 5-isomer
AF594 is a bright water-soluble dye that is not sensitive to pH changes within the range from 4 to 10. This red-fluorescent dye is the best alternative to Texas Red, so it is commonly used for flow cytometry and fluorescent microscopy.,AF594 activated ester is used for labeling proteins, peptides, antibodies, and any molecules containing an -NH2 group (such as amino-modified oligonucleotides); it results in the formation of stable amide bonds between the dye and the target molecule. The best result in conjugation reaction achieved at pH from 7 to 9.,AF594 can be used for protein labeling with a high molar dye-to-protein ratio. The resulting conjugates with a high degree of labeling (DOL) do not exhibit significant fluorescence quenching. In contrast, the conjugates have brighter fluorescence, which allows increasing the lowest limit of detection of the labeled product. Grades: NMR 1H, HPLC-MS (95%). CAS No. 1638544-48-5. Molecular formula: C51H67N5O13S2. Mole weight: 1022.23.
Afelimomab
Afelimomab (MAK 195F) is an anti-tumor necrosis factor F(ab')2 monoclonal antibody fragment. Afelimomab can be used for the research of sepsis [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MAK 195F. CAS No. 156227-98-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99425.
Aflibercept
Aflibercept (VEGF Trap) is a soluble decoy VEGFR constructed by fusing the Ig domains of VEGFR 1 and VEGFR 2 with the Fc region of human IgG1. Aflibercept inhibits VEGF signaling by reducing VEGF-regulated processes. Aflibercept can be used for thr research of age-related macular degeneration (AMD) and cardiovascular disease [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: VEGF Trap; VEGF-TRAPR1R2; VEGF-trapR1. CAS No. 862111-32-8. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-108801.
Aflibercept (VEGF Trap)
Aflibercept (VEGF Trap) is a soluble decoy VEGFR constructed by fusing the Ig domains of VEGFR 1 and VEGFR 2 with the Fc region of human IgG1. Aflibercept inhibits VEGF signaling by reducing VEGF-regulated processes. Aflibercept can be used for thr research of age-related macular degeneration (AMD) and cardiovascular disease [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 862111-32-8. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-108801A.
AGN 194310
A high affinity pan-RAR antagonist (AGN194310, K(d) for binding to RARs = 2-5 nM) inhibited colony formation (by 50%) by all three lines at 16-34 nM, and led to a transient accumulation of flask-cultured cells in G1 followed by apoptosis. AGN194310 is 12-22 fold more potent than all-trans retinoic acid (ATRA) against cell lines and also more potent in inhibiting the growth of primary prostate carcinoma cells. The administration of all-trans retinoic acid to VAD mice resulted in a transient reduction in NF-kappaB activity and, conversely, a single dose of the RAR-pan-antagonist, AGN 194310, administered to control mice, led to a marked, transient induction of whole-body luminescence. Mice were treated with AGN194310, a synthetic retinoid that antagonises the physiological function of the three RAR isotypes (alpha, beta, gamma) but does not interact with RXRs. Analyses of the granulocytic lineage using Gr-1, c-Kit and CD11b antibodies, demonstrated that granulocyte numbers were strikingly increased across haemopoietic compartments in all AGN194310-treated mice. A significant increase in the frequency of progenitor cells containing granulocytes was observed in the bone marrow of mice following treatment with AGN194310. Synonyms: AGN194310; AGN-194310; VTP194310; VTP 194310; VTP-194310. Grades: >98%. CAS No. 229961-45-9. Molecular formula: C28H24O2S. Mole weight: 424.55.
Aldafermin
Aldafermin (NGM282) is an analog of fibroblast growth factor 19. Aldafermin can be used for the research of nonalcoholic steatohepatitis (NASH) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: NGM282. CAS No. 1616639-03-2. Pack Sizes: 500 μg; 1 mg. Product ID: HY-P99428.
Alefacept
Alefacept (BG 9273) is a human lymphocyte function-associated antigen 3/immunoglobulin 1 fusion protein. Alefacept can be used for the research of chronic plaque psoriasis [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BG 9273; Human LFA 3IgG fusion protein; LFA 3TIP. CAS No. 222535-22-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99429.
Alemtuzumab
Alemtuzumab (Campath-IH) is a humanized monoclonal antibody against CD52. Alemtuzumab does not cross-react with murine CD52. Alemtuzumab selectively targets the CD52 antigen to induce profound lymphocyte depletion, followed by recovery of T and B cells with regulatory phenotypes. Alemtuzumab is capable of complement-dependent cytotoxicity and antibody-dependent cell-mediated cytotoxicity (ADCC), as well as induction of apoptosis. Alemtuzumab has the potential for B-cell chronic lymphocytic leukaemia research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Campath-IH. CAS No. 216503-57-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P9948.
Alirocumab
Alirocumab is an anti-PCSK9 human monoclonal antibody. Alirocumab inhibits PCSK9. Alirocumab reduces NLRP3 inflammasome , regulates Nrf2/HO-1 , HMGB1/NF-κB and Fractalkine/CX3CR1. Alirocumab increases the ability of the liver to bind LDL-cholesterol (LDL-C) and reduces levels of LDL-C in blood. Alirocumab improves atherosclerosis and inflammation [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN 727; SAR 236553. CAS No. 1245916-14-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9928.
Alirocumab (anti-PCSK9)
Alirocumab (anti-PCSK9) is an anti-PCSK9 human monoclonal antibody. Alirocumab (anti-PCSK9) inhibits PCSK9. Alirocumab (anti-PCSK9) reduces NLRP3 inflammasome , regulates Nrf2/HO-1 , HMGB1/NF-κB and Fractalkine/CX3CR1. Alirocumab (anti-PCSK9) increases the ability of the liver to bind LDL-cholesterol (LDL-C) and reduces levels of LDL-C in blood. Alirocumab (anti-PCSK9) improves atherosclerosis and inflammation [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN 727(anti-PCSK9); SAR 236553(anti-PCSK9). CAS No. 1245916-14-6. Pack Sizes: 1 mg; 2 mg; 5 mg. Product ID: HY-P9928A.
Alkaline Phosphatase from Bovine, Recombinant
Alkaline phosphatase (ALP, ALKP, ALPase, Alk Phos) (EC 3.1.3.1) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. The process of removing the phosphate group is called dephosphorylation. As the name suggests, alkaline phosphatases are most effective in an alkaline environment. It is sometimes used synonymously as basic phosphatase. Applications: Alkaline phosphatase is used for conjugation to antibodies and other proteins for elisa, western blotting, and hist ochemical detection. it is routinely used to dephosphorylate proteins and nucleic acids. it may be used for protein label...ic acid phosphatase using a fluorogenic assay. it is commonly used as a "reporter" in detection systems, in which it is conjugated to a protein (antibody, streptavidin, etc.) that specifically recognizes a target molecule. alkaline phosphatase has also been used to dephosphorylate casein. Group: Enzymes. Synonyms: Alkaline phosphatase; ALP; ALKP; ALPase; Alk Phos; EC 3.1.3.1; Alkaline phosphomonoesterase; Glycerophosphatase; Phosphomonoesterase. Enzyme Commission Number: EC 3.1.3.1. CAS No. 9001-78-9. ALP. Mole weight: apparent mol wt 160 kDa. Activity: > 4000 units/mg protein. Storage: 2-8°C. Source: Pichia pastoris. Species: Bovine. Alkaline phosphatase; ALP; ALKP; AL
Alnuctamab
Alnuctamab (EM901) is an asymmetric 2-arm, humanized IgG T-cell engager (TCE). Alnuctamab can be used for immune research, serving as a B-cell maturation antigen (BCMA) x CD3 T-cell engager (TCE). Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: EM901; CC-93269. CAS No. 2296827-07-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99430.
α-2,3-Sialyltransferase, Recombinant
Sialyltransferases are enzymes that transfer sialic acid to nascent oligosaccharide. Each sialyltransferase is specific for a particular sugar substrate. Sialyltransferases add sialic acid to the terminal portions of the sialylated glycolipids (gangliosides) or to the N-or O-linked sugar chains of glycoproteins. Sialyltransferases belong to glycosyltransferase family 29 (CAZY GT_29) which use a nucleotide monophosphosugar as the donor (CMP-NeuA) instead of a nucleotide diphosphosugar. Α-2,3-sialyltransferase is used for in vitro sialylation of all galβ1-4glcnac units on glycoproteins, such as monoclonal antibodies (mabs). clear colorless to slightly colored so...d. Group: Enzymes. Synonyms: α (2,3)-Sialyltransferase; Beta-galactoside alpha-2,3-sialyltransferase; Beta-galactosamide alpha-2,3-sialyltransferase; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase. Purity: > 90%. α-Sialyltransferase. Mole weight: 34.5 kDa. Activity: > 80 U/ug (1 Unit = pmol / min, using 10 ug enzyme in Sialyltransferase activity assay). Stability: at -15°C to -25°C: within specification range for 12 months. Appearance: clear, colorless to slightly colored solution. α-2,3-Sialyltransferase; α (2,3)-Sialyltransferase; Beta-galactoside alpha-2,3-sialyltransferase; Beta-galactosamide alpha-2,3-sialyltransferase
Alsevalimab
Alsevalimab is a human monoclonal antibody against B7-H4 [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2254029-91-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99242.
Alum Adjuvant
Alum Adjuvant is insoluble white colloidal suspension of aluminum hydroxide used to potentiate immune response. Antigen adsorbs on the aluminum hydroxide precipitate and when injected form a depot of insoluble antigen at injection site which attracts immune cells and enhance immune response. It is used to raise polyclonal and monoclonal antibodies and is less toxic when compared to Freunds complete adjuvant. Synonyms: Mixture of Aluminum Hydroxide and Magnesium Hydroxide.
AM-8508
AM-8508 is a selective Phosphatidylinositol-3-kinase delta (PI3Kδ) inhibitor. AM-8508 exhibits good cellular potency (in vitro pAKT IC50 = 4.6 nM ) and excellent HWB potency (HWB (pAKT) IC50 = 2.7 nM). AM-8508 inhibits KLH-specific antibodies in animal models and it may become a drug candidate for the treatment of human inflammatory diseases. Uses: Inflammatory diseases. Synonyms: AM-8508; AM 8508; AM8508. (S)-4-amino-6-((1-(6-fluoro-1-(pyridin-3-yl)-1H-benzo[d]imidazol-2-yl)ethyl)amino)pyrimidine-5-carbonitrile. Grades: 98%. CAS No. 1338483-67-2. Molecular formula: C19H15FN8. Mole weight: 374.14.
AM-9635
AM-9635 is a selective Phosphatidylinositol-3-kinase delta (PI3Kδ) inhibitor. AM-9635 exhibits good cellular potency (in vitro pAKT IC50 = 4.2 nM ). AM-9635 can inhibit KLH-specific IgG and IgM in a dosedependent manner and it is well tolerated at all doses. AM-96352 shows significantly reduced IgG and IgM specific antibodies. Synonyms: AM-9635; AM 9635; AM9635. (S)-4-amino-6-((1-(6-fluoro-1-(5-fluoropyridin-3-yl)-1H-benzo[d]imidazol-2-yl)ethyl)amino)pyrimidine-5-carbonitrile. Grades: 98%. CAS No. 1338483-10-5. Molecular formula: C19H14F2N8. Mole weight: 392.36.
Amatuximab
Amatuximab (MORab-009) is a chimeric, humanized IgG1/k MAb that targets the cell surface mesothelin (MSLN). Mesothelin is a glycosylphosphatidyl inositol (GPI)-anchored membrane glycoprotein, which is present in a restricted set of normal adult tissues such as the mesothelium [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MORab-009. CAS No. 931402-35-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99006.
Amine-Doxorubicin Liposome (PEGylated)
This formulation is Doxorubicin Liposome (PEGylated) with the amine group, which can react with peptides, antibodies and other NHS-containing biomolecules or nanoparticles. The free carboxyl group on the antibody, peptide or protein can be activated by EDC/sulfo-NHS, and then covalently conjugated to the lipids through displacement of sulfo-NHS groups by amine groups of the liposome. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes.
Amivantamab
Amivantamab (JNJ-61186372) is a human EGFR-MET bispecific antibody with immune anticancer activity. Amivantamab inhibits ligand binding, promotes endocytosis and degradation of receptor-antibody complexes, and induces Fc-dependent cytokinesis in macrophages and antibody-dependent cytotoxicity in natural killer cells [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: JNJ-61186372. CAS No. 2171511-58-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9977.
Amlitelimab
Amlitelimab () is an anti- OX40 Ligand (OX40L) monoclonal antibody (mAb). Amlitelimab inhibits OX40-OX40L interaction, and can be used in the research of atopic dermatitis [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: KY1005; SAR445229. CAS No. 2378692-15-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99434.
Ammonium Sulfate, ACS
Used for the precipitation or fractionation of proteins or for purification of antibodies. Useful for crystallographic analysis of nucleic acids and proteins. Group: Biochemicals. Grades: ACS Grade. CAS No. 7783-20-2. Pack Sizes: 500g, 1Kg, 2.5Kg, 5Kg. Molecular Formula: (NH4)2SO4, Molecular Weight: 132.14. US Biological Life Sciences.
Worldwide
Amubarvimab
Amubarvimab (BRII-196) is a human IgG1 mAb that bind to non-competing epitopes on the receptor binding domain (RBD) of spike protein , with a K D of 5.88 nM. Amubarvimab can effectively neutralize SARS-CoV-2 variants [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BRII-196. CAS No. 2509447-07-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99435.
Would you like to list your products on USA Chemical Suppliers?
Our database is helping our users find suppliers everyday.