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| Product | Description | |
|---|---|---|
| Antibody Drug Conjugate | Antibody Drug Conjugate. Group: Single wall cnt. >80% (SWNT). |  |
| Antibody Drug Conjugate Prostate Cancer | Antibody Drug Conjugate Prostate Cancer. Group: Single wall cnt. >90% (SWNT). | |
| Pancreatic Cancer Antibody Drug Conjugate | Pancreatic Cancer Antibody Drug Conjugate. Group: Single wall cnt. >95% (SWNT). | |
| 1,?1-?Dimethylethyl Ester 3-?Bromo-?6-?fluoro-?2-pyridinecarboxylic Acid | 1,?1-?Dimethylethyl Ester 3-?Bromo-?6-?fluoro-?2-pyridinecarboxylic Acid is a useful reagent in preparation of cell peremeable Bcl-xl inhibitor and antibody drug conjugates. Group: Biochemicals. Grades: Highly Purified. CAS No. 1430753-76-6. Pack Sizes: 25mg, 50mg. Molecular Formula: C10H11BrFNO2, Molecular Weight: 276.1. US Biological Life Sciences. |  Worldwide |
| 1-Boc-azetidine-3-carboxylic acid | 1-Boc-azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-Boc-azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 142253-55-2. Pack Sizes: 1 g; 5 g. Product ID: HY-40141. |  |
| 1-Cbz-azetidine-3-carboxylic acid | 1-Cbz-azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-Cbz-azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 97628-92-7. Pack Sizes: 10 g; 25 g. Product ID: HY-W004868. | |
| 1-N-Boc-3-hydroxyazetidine | 1-N-Boc-3-hydroxyazetidine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-N-Boc-3-hydroxyazetidine is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Group: Signaling pathways. CAS No. 141699-55-0. Pack Sizes: 25 g; 50 g. Product ID: HY-40142. | |
| 2-(2-(2-Aminoethoxy)ethoxy)acetic acid | H2N-PEG2-CH2COOH belongs to a polyethylene glycol (PEG) linker covalently bound to E3 Ligase binding group (E3LB) and protein binding group (PB). H2N-PEG2-CH2COOH is a PEG derivative containing an amino group with a terminal carboxylic acid. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. PEG Linkers may be useful in the development of antibody drug conjugates and PROTACs. Synonyms: Amino-PEG2-CH2CO2H; Amino-PEG2-CH2COOH; Amino-PEG2-acetic acid. Grades: ≥95%. CAS No. 134978-97-5. Molecular formula: C6H13NO4. Mole weight: 163.17. |  |
| (2R,4R)-4-Hydroxypyrrolidine-2-carboxylic acid hydrochloride | cis-4-Hydroxy-D-proline hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). cis-4-Hydroxy-D-proline hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Group: Signaling pathways. CAS No. 77449-94-6. Pack Sizes: 25 g; 100 g. Product ID: HY-76104. | |
| (2R,4S)-1-(tert-Butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid | N-tert-Butoxycarbonyl-trans-4-hydroxy-D-proline is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-tert-Butoxycarbonyl-trans-4-hydroxy-D-proline is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Group: Signaling pathways. CAS No. 147266-92-0. Pack Sizes: 5 g; 10 g; 25 g. Product ID: HY-77593. | |
| 6-Azidohexanoic acid NHS ester | A noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: N3-C5-NHS ester. Grades: ≥ 95% (HPLC). CAS No. 866363-70-4. Molecular formula: C10H14N4O4. Mole weight: 254.24. | |
| 7-MAD-MDCPT | 7-MAD-MDCPT, a Camptothecin analog, is a toxin payload in antibody drug conjugates (ADCs)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 765871-81-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-132162. | |
| ADC Control Human IgG1-Deruxtecan (DAR 4) | ADC Control Human IgG1-Deruxtecan (DAR 4) is a humanized monoclonal antibody that is an isotype control of ADC human IgG1-Deruxtecan and can inhibit DNA topoisomerase I. The antibody portion is Human IgG1 kappa, Isotype Control (HY-P99001), and the drug-linker conjugate for ADC is Deruxtecan (HY-13631E)[1]. Uses: Scientific research. Group: Inhibitory antibodies. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-164152. | |
| ADC Control Human IgG1-Deruxtecan (DAR 8) | ADC Control Human IgG1-Deruxtecan (DAR 8) is a humanized monoclonal antibody that is an isotype control of ADC human IgG1-Deruxtecan and can inhibit DNA topoisomerase I. The antibody portion is Human IgG1 kappa, Isotype Control (HY-P99001), and the drug-linker conjugate for ADC is Deruxtecan (HY-13631E)[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-164152A. | |
| ADC Control Human IgG1-DM4 | ADC Control Human IgG1-DM4 is an isotype control of ADC Human IgG1-DM4. The antibody portion is Human IgG1 kappa, Isotype Control (HY-P99001), and the drug-linker conjugate for ADC is SPDB-DM4 (HY-12460). Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-164669. | |
| ADC Control Human IgG1-SN-38 | ADC Control Human IgG1-SN-38 is an isotype control of ADC Human IgG1-SN-38. The antibody portion is Human IgG1 kappa, Isotype Control (HY-P99001), and the drug-linker conjugate for ADC is CL2A-SN-38 (HY-128946). Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-164668. | |
| ADC Control Human IgG1-vcMMAE | ADC Control Human IgG1-vcMMAE is a humanized monoclonal antibody that is an isotype control of ADC human IgG1-vcMMAE and can inhibit tubulin polymerization. The antibody portion is Human IgG1 kappa, Isotype Control (HY-P99001), and the drug-linker conjugate for ADC is vcMMAE (HY-15575)[1]. Uses: Scientific research. Group: Inhibitory antibodies. Pack Sizes: 1 mg; 5 mg. Product ID: HY-164153. | |
| ADC Control Human IgG1-vcMMAF | ADC Control Human IgG1-vcMMAF is a humanized monoclonal antibody that is an isotype control of ADC human IgG1-vcMMAF and can inhibit tubulin polymerization. The antibody portion is Human IgG1 kappa, Isotype Control (HY-P99001), and the drug-linker conjugate for ADC is MC-Val-Cit-PAB-MMAF (vcMMAF; HY-112786)[1]. Uses: Scientific research. Group: Inhibitory antibodies. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-164154. | |
| AEEA-AEEA | AEEA-AEEA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: 17-amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecan-1-oic acid. CAS No. 1143516-05-5. Molecular formula: C12H24N2O7. Mole weight: 308.33. | |
| Amine-Doxorubicin Liposome (PEGylated) | This formulation is Doxorubicin Liposome (PEGylated) with the amine group, which can react with peptides, antibodies and other NHS-containing biomolecules or nanoparticles. The free carboxyl group on the antibody, peptide or protein can be activated by EDC/sulfo-NHS, and then covalently conjugated to the lipids through displacement of sulfo-NHS groups by amine groups of the liposome. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes. |  |
| Amino-PEG3-t-butyl acetate | NH2-PEG3-C1-Boc is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 5 can be used in the synthesis of a series of PROTACs. NH2-PEG3-C1-Boc is a PEG derivative containing an amino group with a t-butyl protected carboxyl group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions. PEG Linkers may be useful in the development of antibody drug conjugates, PROTACs and drug delivery methods. Synonyms: NH2-PEG3-C1-Boc; PROTAC Linker 5; Amino-PEG3-CH2CO2-t-butyl ester; H2N-PEG3-CH2COOtBu; Acetic acid, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester. Grades: >95%. CAS No. 189808-70-6. Molecular formula: C12H25NO5. Mole weight: 263.33. | |
| Amino-PEG4-alcohol | Amino-PEG4-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Amino-PEG4-alcohol is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Uses: Designed for use in research and industrial production. Additional or Alternative Names: 11-Amino-3,6,9-trioxaundecanol. Product Category: Amino PEG Linkers. Appearance: Liquid. CAS No. 86770-74-3. Molecular formula: C8H19NO4. Mole weight: 193.24. Purity: >90%. IUPACName: 2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethanol. Canonical SMILES: C(COCCOCCOCCO)N. Density: 1.1±0.1 g/cm3. Product ID: ACM86770743. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Amino-PEG4-CH2COOH | Amino-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Amino-PEG4-CH2COOH is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Uses: Designed for use in research and industrial production. Additional or Alternative Names: Amino-PEG4-acetic acid. Product Category: Amino PEG Linkers. Appearance: Liquid. CAS No. 195071-49-9. Molecular formula: C10H21NO6. Mole weight: 251.28. Purity: >90%. IUPACName: 2-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethoxy]acetic acid. Canonical SMILES: C(COCCOCCOCCOCC(=O)O)N. Density: 1.156±0.06 g/cm3. Product ID: ACM195071499. Alfa Chemistry ISO 9001:2015 Certified. | |
| Amino-PEG6-alcohol | Amino-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Uses: Designed for use in research and industrial production. Additional or Alternative Names: Amino-PEG6-OH. Product Category: Amino PEG Linkers. Appearance: Liquid. CAS No. 39160-70-8. Molecular formula: C12H27NO6. Mole weight: 281.35. Purity: >90%. IUPACName: 2-[2-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol. Canonical SMILES: C(COCCOCCOCCOCCOCCO)N. Density: 1.1±0.1 g/cm3. Product ID: ACM39160708. Alfa Chemistry ISO 9001:2015 Certified. | |
| Anetumab | Anetumab (Anti-MSLN Antibody) is an anti-mesothelin ( MSLN ) antibody. MSLN is a tumor-associated antigen. Anetumab can be used to synthesis Anetumab ravtansine, a MSLN-targeting antibody-drug conjugate (ADC). Anetumab can be used for the research of malignant tumor [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-MSLN Antibody. CAS No. 1954758-84-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99352. | |
| Anti-SEZ6 Antibody (SC17) | Anti-SEZ6 Antibody (SC17) is an anti-SEZ6 IgG1 monoclonal antibody. Anti-SEZ6 Antibody (SC17) can be used to synthesize antibody-drug conjugates (ADC) product, ABBV-011[1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ABBV-011 antibody; ABBV-706 antibody. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P991041. | |
| ATFB-SE | A useful protective group in antibody drug conjugates. Synonyms: N-Succinimidyl 4-Azido-2,3,5,6-tetrafluorobenzoate;4-azido-2,3,5,6-tetrafluorobenzoic acid 2,5-dioxo-pyrrolidin-1-yl ester. Grades: ≥98%. CAS No. 126695-58-7. Molecular formula: C11H4F4N4O4. Mole weight: 332.17. | |
| Auristatin F | Auristatin F, a synthetic analog of dolastatin 10, is a cytotoxic tubulin modifier with potent and selective antitumor activity. It is an MMAF analog and cytotoxin in Antibody-drug conjugates. Uses: Adcs cytotoxin. Synonyms: N,N-Dimethyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-L-phenylalanine; L-Valinamide, N,N-dimethyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-; N,N-Dimethyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S)-1-carboxy-2-phenylethyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}-3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide. Grades: ≥97% by HPLC. CAS No. 163768-50-1. Molecular formula: C40H67N5O8. Mole weight: 745.99. | |
| AZ14170133 | AZ14170133 (SG 3932) is a Drug-Linker Conjugates for ADC, which comprises a topoisomerase inhibitor and a linker for ligand unit connecting. AZ14170133 can be used to synthesis antibody-drug conjugate (ADC)[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SG 3932; AZ-0133. CAS No. 2495742-34-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145399. | |
| Azetidine-3-carboxylic acid | Azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2. Uses: Scientific research. Group: Signaling pathways. CAS No. 36476-78-5. Pack Sizes: 10 g; 25 g. Product ID: HY-Y0530. | |
| Azido-PEG10-amine | Azido-PEG10-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: N3-PEG10-CH2CH2NH2; 32-Azido-3,6,9,12,15,18,21,24,27,30-decaoxadotriacontan-1-amine; O-(2-Aminoethyl)-O-(2-azidoethyl)nonaethylene Glycol; N3-PEG10-NH2. Grades: >97%. CAS No. 912849-73-1. Molecular formula: C22H46N4O10. Mole weight: 526.62. | |
| Azido-PEG2-C2-amine | Azido-PEG2-C2-amine (N3-PEG2-CH2CH2NH2) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG2-C2-amine is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2]. Azido-PEG2-C2-amine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N3-PEG2-CH2CH2NH2. CAS No. 166388-57-4. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-140213. | |
| Azido-PEG2-NHS ester | Azido-PEG2-NHS ester is a non-cleavable 2-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs). Synonyms: Azido-PEG2-CH2CO2-NHS; N3-PEG2-C2-NHS ester; Propanoic acid, 3-[2-(2-azidoethoxy)ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester; N3-PEG2-CH2CH2COONHS Ester; Azido-PEG2-NHS; N3-PEG2-SPA; 1-({3-[2-(2-Azidoethoxy)ethoxy]propanoyl}oxy)-2,5-pyrrolidinedione; 2,5-Pyrrolidinedione, 1-[3-[2-(2-azidoethoxy)ethoxy]-1-oxopropoxy]-; 2,5-Dioxo-1-pyrrolidinyl 3-[2-(2-azidoethoxy)ethoxy]propanoate; N-Succinimido 9-azido-4,7-dioxanonanoate. Grades: ≥98%. CAS No. 1312309-64-0. Molecular formula: C11H16N4O6. Mole weight: 300.27. | |
| Azido-PEG3-NHS ester | N3-PEG3-C2-NHS ester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). Uses: Designed for use in research and industrial production. Additional or Alternative Names: N3-PEG3-C2-NHS ester. Product Category: Azido PEG Linkers. Appearance: Solid or viscous liquid. CAS No. 1245718-89-1. Molecular formula: C13H20N4O7. Mole weight: 344.32. Purity: >90%. IUPACName: (2,5-Dioxopyrrolidin-1-yl) 3-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]propanoate. Canonical SMILES: C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCN=[N+]=[N-]. Product ID: ACM1245718891. Alfa Chemistry ISO 9001:2015 Certified. | |
| Azido-PEG3-Val-Cit-PAB-PNP | Azido-PEG3-Val-Cit-PAB-PNP is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG3-Val-Cit-PAB-PNP is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2]. Azido-PEG3-Val-Cit-PAB-PNP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2055047-18-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-140150. | |
| Azido-PEG4-NHS ester | N3-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). Uses: Designed for use in research and industrial production. Additional or Alternative Names: N3-PEG4-C2-NHS ester. Product Category: Azido PEG Linkers. Appearance: Solid or viscous liquid. CAS No. 944251-24-5. Molecular formula: C15H24N4O8. Mole weight: 388.37. Purity: >90%. IUPACName: (2,5-Dioxopyrrolidin-1-yl) 3-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]propanoate. Canonical SMILES: C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCN=[N+]=[N-]. Product ID: ACM944251245. Alfa Chemistry ISO 9001:2015 Certified. | |
| Azido-PEG5-alcohol | Azido-PEG5-alcohol is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG5-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2]. Azido-PEG5-alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 86770-68-5. Pack Sizes: 250 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-130211. | |
| Azido-PEG5-alcohol | Azido-PEG5-alcohol is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG5-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-Azidohexaethylene glycol. Product Category: Azido PEG Linkers. Appearance: Oil. CAS No. 86770-68-5. Molecular formula: C10H21N3O5. Mole weight: 263.29. Purity: >90%. IUPACName: 2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethanol. Canonical SMILES: C(COCCOCCOCCOCCO)N=[N+]=[N-]. Product ID: ACM86770685. Alfa Chemistry ISO 9001:2015 Certified. | |
| Azido-PEG6-alcohol | Azido-PEG6-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG6-alcohol is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Uses: Designed for use in research and industrial production. Additional or Alternative Names: N3-PEG6-OH. Product Category: Azido PEG Linkers. Appearance: Liquid. CAS No. 86770-69-6. Molecular formula: C12H25N3O6. Mole weight: 307.34. Purity: >90%. IUPACName: 2-[2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol. Canonical SMILES: C(COCCOCCOCCOCCOCCO)N=[N+]=[N-]. Product ID: ACM86770696. Alfa Chemistry ISO 9001:2015 Certified. | |
| Azido-PEG8-amine | Azido-PEG8-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: O-(2-Aminoethyl)-O'-(2-azidoethyl)heptaethylene glycol; N3-PEG8-CH2CH2NH2; Azido-PEG8-NH2; N3-PEG8-NH2; 26-Azido-3,6,9,12,15,18,21,24-octaoxahexacosan-1-amine. Grades: ≥90%. CAS No. 857891-82-8. Molecular formula: C18H38N4O8. Mole weight: 438.52. | |
| Azintuxizumab | Azintuxizumab is an anti- SLAMF7 human IgG4κ monoclonal antibody. Azintuxizumab can be used in the synthesis of antibody-drug conjugate (ADC), Azintuxizumab vedotin [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1826819-57-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99453. | |
| Azintuxizumab vedotin | Azintuxizumab vedotin (ABBV-838) is an antibody-drug conjugate (ADC) targeting a unique epitope of CD2 subset 1, a cell-surface glycoprotein expressed on multiple myeloma cells[1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ABBV-838. CAS No. 1826819-58-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99454. | |
| BCN-PEG3-Biotin | BCN-PEG3-Biotin is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. BCN-PEG3-Biotin is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1263166-92-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130924. | |
| β-Amanitin | β-Amanitin is a cyclic peptide toxin in the poisonous Amanita phalloides mushroom. β-Amanitin inhibits eukaryotic RNA polymerase II and III. β-Amanitin inhibits protein synthesis. β-Amanitin can be used as a cytotoxic component of antibody-drug conjugates (ADCs). Synonyms: 2-[34-butan-2-yl-13-(3, 4-dihydroxybutan-2-yl)-8, 22-dihydroxy-2, 5, 11, 14, 27, 30, 33, 36, 39-nonaoxo-27lambda4-thia-3, 6, 12, 15, 25, 29, 32, 35, 38-nonazapentacyclo[14.12.11.06, 10.018, 26.019, 24]nonatriaconta-18(26), 19(24), 20, 22-tetraen-4-yl]acetic acid. Grades: >98.0%. CAS No. 21150-22-1. Molecular formula: C39H53N9O15S. Mole weight: 919.95. | |
| β-Amanitin | β-Amanitin is a cyclic peptide toxin in the poisonous Amanita phalloides mushroom. β-Amanitin inhibits inhibits eukaryotic RNA polymerase II and III. β-Amanitin inhibits protein synthesis. β-Amanitin can be used as a cytotoxic component of antibody-drug conjugates (ADCs) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 21150-22-1. Pack Sizes: 100 μg; 500 μg; 1 mg. Product ID: HY-125586. | |
| β-D-glucuronide-pNP-carbonate | ?-D-glucuronide-pNP-carbonate is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 894095-98-8. Pack Sizes: 50 mg; 100 mg; 250 mg; 1 g. Product ID: HY-136329. | |
| Biotin-PEG1-NH2 | Biotin-PEG1-NH2 is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 811442-85-0. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W096135. | |
| BMPS | BMPS is a nonclaevable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Uses: Scientific research. Group: Signaling pathways. CAS No. 55750-62-4. Pack Sizes: 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-42146. | |
| Boc-Cystamine | Boc-Cystamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 485800-26-8. Pack Sizes: 100 mg; 250 mg. Product ID: HY-140098. | |
| Boc-Gly-Gly-Phe-Gly-OH | Boc-Gly-Gly-Phe-Gly-OH, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC). Uses: Scientific research. Group: Peptides. CAS No. 187794-49-6. Pack Sizes: 100 mg; 250 mg; 1 g; 5 g; 10 g. Product ID: HY-P1449. | |
| Boc-Gly-Gly-Phe-Gly-OH | Boc-Gly-Gly-Phe-Gly-OH is a self-assembly of N- and C-protected tetrapeptide. It is also a protease-cleavable linker for antibody-drug conjugates (ADCs). Synonyms: N-tert-butoxycarbonyl-glycyl-glycyl-L-phenylalanyl-glycine; N-(tert-butoxycarbonyl)-glycylglycyl-L-phenylalanylglycine; (S)-12-Benzyl-2,2-dimethyl-4,7,10,13-tetraoxo-3-oxa-5,8,11,14-tetraazahexadecan-16-oic acid. Grades: >95%. CAS No. 187794-49-6. Molecular formula: C20H28N4O7. Mole weight: 436.46. | |
| Boc-Gly-Gly-Phe-Gly-OH TFA | Boc-Gly-Gly-Phe-Gly-OH TFA, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC). Synonyms: Boc-Gly-Gly-Phe-Gly-OH trifluoroacetic acid; N-tert-butoxycarbonyl-glycyl-glycyl-L-phenylalanyl-glycine trifluoroacetic acid. Grades: >98%. Molecular formula: C22H29F3N4O9. Mole weight: 550.48. | |
| BOC-L-Hydroxyproline | Boc-L-Hydroxyproline 13726-69-7 is Powder. it is also known as N-Boc-L-Hydroxyproline and trans-N-tert-Butoxycarbonyl-4-hydroxy-L-proline. it is use in API Synthesis and Synthesis Industry. Storage: Keep container tightly closed. CAS No. 13726-69-7. Product ID: PAP-0013. Molecular formula: C10H17NO5. Category: Amino acid. Product Keywords: Amino Acid Series; BOC-L-Hydroxyproline; PAP-0013; Amino acid; C10H17NO5; 13726-69-7. Color: White to off-white. EC Number: 604-011-7. Physical State: Powder. Solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. Storage: Keep in dark place,Sealed in dry,Room Temperature. Applications: Boc-Hyp-OH is a non-cleavable ADC connector used to synthesize antibody drug conjugates (ADCs). Boc Hyp OH is also an alkyl chain-based PROTAC linker that can be used to synthesize PROTAC. Boiling Point: 390.9±42.0 °C(Predicted). Melting Point: 123-127 °C(lit.). Density: 1.312±0.06 g/cm3(Predicted). Product Description: Boc-Hyp-OH is a non-cleavable ADC connector used to synthesize antibody drug conjugates (ADCs). Boc Hyp OH is also an alkyl chain-based PROTAC linker that can be used to synthesize PROTAC. |  |
| Boc-NH-PEG4-CH2CH2COOH | Boc-NH-PEG4-CH2CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC[1]. Boc-NH-PEG4-CH2CH2COOH is also a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC)[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 756525-91-4. Pack Sizes: 100 mg; 250 mg. Product ID: HY-W040132. | |
| Boc-NH-PEG4-CH2CH2NH2 | Boc-NH-PEG4-CH2CH2NH2 a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-NH-PEG4-CH2CH2NH2 is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 811442-84-9. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W008352. | |
| Boc-Val-Cit-OH | Boc-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: (2S) -5- (carbamoylamino) -2- [ [ (2S) -3-methyl-2- [ (2-methylpropan-2-yl) oxycarbonylamino] butanoyl] amino] pentanoic acid. Grades: ≥95.0%. CAS No. 870487-08-4. Molecular formula: C16H30N4O6. Mole weight: 374.43. | |
| Brentuximab | Brentuximab is a monoclonal antibody targeting CD30. Brentuximab is conjugated with monomethyl auristatin E (MMAE) (HY-15162) to form the antibody-drug conjugate Brentuximab vedotin (HY-P99107), which can induce apoptosis in primary effusion lymphoma cells. Brentuximab vedotin exhibits antitumor activity with an IC 50 of 10 nM against human CD30+ cancer cells [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2088770-90-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99151. | |
| BS3 Crosslinker | BS3 Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 82436-77-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124329. | |
| Cetuximab MMAE | Cetuximab MMAE is an antibody-drug conjugate (ADC) consisting of the EGFR-targeting humanized monoclonal antibody Cetuximab (HY-P9905) conjugated to VcMMAE (HY-15575). Cetuximab MMAE exhibits antitumor activity[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-171135. | |
| Dap-NE hydrochloride | Dap-NE hydrochloride is a dipeptide hydrochloride and a cleavable ADC Linker.Dap-NE hydrochloride can be used to connect Antibody and toxin molecules (Cytotoxin) to synthesize Antibody-Drug Conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2019182-02-4. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-78932A. | |
| Datopotamab | Datopotamab (CDP7657) is a humanized anti trophoblast cell surface antigen 2 ( TROP2 ) antibody. Datopotamab can generate antibody drug conjugates (ADC) (HY-141598) with DNA topoisomerase I inhibitor Deruxtecan (HY-13631E). Datopotamab can be used in the study of triple negative breast cancer and non-small cell lung cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2267989-53-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99843. | |
| Datopotamab deruxtecan | Datopotamab deruxtecan (DS-1062; Dato-DXd) is a trophoblast cell surface antigen 2 (TROP2)-directed antibody-drug conjugate (ADC). Datopotamab deruxtecan has a potent antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DS-1062; Dato-DXd. CAS No. 2238831-60-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-141598. | |
| DBCO-amine | DBCO-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. DBCO-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1255942-06-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-W000423. | |
| DBCO-Maleimide | DBCO-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. DBCO-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1395786-30-7. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-116270. | |
| DBCO-NHS ester | DBCO-NHS ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. DBCO-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1353016-71-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-42973. | |
| DBCO-NHS ester 2 | DBCO-NHS ester 2 is a cleavable linker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 2 is a derivative of Dibenzylcyclooctyne (DBCO) used in copper-free click chemistry[1]. DBCO-NHS ester 2 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1384870-47-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115524. | |
| DBCO-PEG3-NHS ester | DBCO-PEG3-NHS ester (cpmpd 45) is a ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2163772-16-3. Pack Sizes: 25 mg; 50 mg. Product ID: HY-156507. | |
| DBCO-PEG4-DBCO | DBCO-PEG4-DBCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. DBCO-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2182601-68-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-130346. | |
| DBCO-PEG4-Maleimide | DBCO-PEG4-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. DBCO-PEG4-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1480516-75-3. Pack Sizes: 25 mg. Product ID: HY-120770. | |
| DBCO-PEG4-Val-Cit-PAB-MMAF | DBCO-PEG4-Val-Cit-PAB-MMAF consists a cleavable 4 unit PEG ADC linker (DBCO-PEG4-Val-Cit-PAB) and a potent tubulin polymerization inhibitor (MMAF). DBCO-PEG4-Val-Cit-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG4-Val-Cit-PAB-MMAF is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2244602-23-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-130990. | |
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