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| Product | Description | |
|---|---|---|
| Apremilast | Apremilast (CC-10004) is an orally available inhibitor of type-4 cyclic nucleotide phosphodiesterase ( PDE-4 ) with an IC 50 of 74 nM. Apremilast inhibits TNF-α release by lipopolysaccharide (LPS) with an IC 50 of 104 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CC-10004. CAS No. 608141-41-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12085. |  |
| Apremilast | Apremilast is an orally available small molecule inhibitor of phosphodiesterase 4 (PDE4). Apremilast specifically inhibits PDE4 and inhibits spontaneous production of TNF-alpha from human rheumatoid synovial cells. Uses: Anti-inflammatory agents, non-steroidal; phosphodiesterase inhibitors. Synonyms: (S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione; (S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide; CC 10004; CC10004; CC-10004. Grades: >98%. CAS No. 608141-41-9. Molecular formula: C22H24N2O7S. Mole weight: 460.50. |  |
| Apremilast-d5 | 2H Labeled Compounds. CAS No. 1258597-47-5. Molecular formula: C22H19D5N2O7S. Mole weight: 465.53. Catalog: ACM1258597475. |  |
| Apremilast Dimer | Apremilast Dimer is an impurity of Apremilast, which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. Synonyms: (S)-N-(2'-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,1',3,3'-tetraoxo-[2,4'-biisoindolin]-4-yl)acetamide. CAS No. 1802246-60-1. Molecular formula: C30H27N3O9S. Mole weight: 605.6. | |
| Apremilast Impurity 11 | Apremilast Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 253168-83-1. Molecular Formula: C20H22N2O6S. Mole Weight: 418.46. Catalog: APB253168831. |  |
| Apremilast Impurity 18 | Apremilast Impurity 18. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(2-(1-(3,4-dimethoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide. Molecular Formula: C21H22N2O7S. Mole Weight: 446.47. Catalog: APB02691. | |
| Apremilast Impurity 18 | Apremilast Impurity 18. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1407140-51-5. Molecular Formula: C20H32N2O6S. Mole Weight: 428.54. Catalog: APB1407140515. | |
| Apremilast Impurity 19 | Apremilast Impurity 19. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(2-(1-(4-ethoxy-3-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide. Molecular Formula: C22H24N2O7S. Mole Weight: 460.5. Catalog: APB02689. | |
| Apremilast Impurity 2 | A metabolite of Apremilast. Synonyms: (R)-Apremilast; N-[2-[(1R)?-1-(3-Ethoxy-4-methoxyphenyl)?-2-(methylsulfonyl)?ethyl]?-2,?3-dihydro-1,?3-dioxo-1H-isoindol-4-yl]?-acetamide. Grades: > 95%. CAS No. 608141-44-2. Molecular formula: C22H24N2O7S. Mole weight: 460.51. | |
| Apremilast Impurity 20 | Apremilast Impurity 20. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-N-(2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-5-yl)acetamide. CAS No. 2201974-01-6. Molecular Formula: C22H24N2O7S. Mole Weight: 460.5. Catalog: APB2201974016. | |
| Apremilast Impurity 20 | Apremilast Impurity 20. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2169153-70-0. Molecular Formula: C10H15NO4S. Mole Weight: 245.29. Catalog: APB2169153700. | |
| Apremilast Impurity 21 | Apremilast Impurity 21. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-5-nitroisoindoline-1,3-dione. Molecular Formula: C20H20N2O8S. Mole Weight: 448.45. Catalog: APB01215. | |
| Apremilast Impurity 22 | Apremilast Impurity 22. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-nitrosophthalic acid. CAS No. 106860-70-2. Molecular Formula: C8H5NO5. Mole Weight: 195.13. Catalog: APB106860702. | |
| Apremilast Impurity 22 | Apremilast Impurity 22. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1450657-28-9. Molecular Formula: C12H16O5S. Mole Weight: 272.32. Catalog: APB1450657289. | |
| Apremilast Impurity 23 | Apremilast Impurity 23. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(hydroxyamino)phthalic acid. CAS No. 202262-76-8. Molecular Formula: C8H7NO5. Mole Weight: 197.14. Catalog: APB202262768. | |
| Apremilast Impurity 23 | Apremilast Impurity 23. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C12H18O5S. Mole Weight: 274.33. Catalog: APB06680. | |
| Apremilast Impurity 24 | Apremilast Impurity 24. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2651-55-0. Molecular Formula: C10H12O4. Mole Weight: 196.2. Catalog: APB2651550. | |
| Apremilast Impurity 25 | Apremilast Impurity 25. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-ethoxy-4-methoxybenzamide. Molecular Formula: C10H13NO3. Mole Weight: 195.22. Catalog: APB02690. | |
| Apremilast Impurity 26 | Apremilast Impurity 26. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-((2-amino-2-(3-ethoxy-4-methoxyphenyl)ethyl)sulfonyl)ethanol. CAS No. 2733250-84-3. Molecular Formula: C13H21NO5S. Mole Weight: 303.37. Catalog: APB2733250843. | |
| Apremilast Impurity 27 | Apremilast Impurity 27. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-acetamido-6- ( (1- (3-ethoxy-4-methoxyphenyl) -2- (methylsulfonyl) ethyl) carbamoyl) benzoic acid. Molecular Formula: C22H26N2O8S. Mole Weight: 478.52. Catalog: APB02688. | |
| Apremilast Impurity 27 | Apremilast Impurity 27. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1384440-16-7. Molecular Formula: C19H20N2O6S. Mole Weight: 404.44. Catalog: APB1384440167. | |
| Apremilast Impurity 29 | Apremilast Impurity 29. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine. CAS No. 608141-42-0. Molecular Formula: C12H19NO4S. Mole Weight: 273.35. Catalog: APB608141420. | |
| Apremilast Impurity 29 | Apremilast Impurity 29. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1384439-80-8. Molecular Formula: C17H16N2O6S. Mole Weight: 376.38. Catalog: APB1384439808. | |
| Apremilast Impurity 30 | Apremilast Impurity 30. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide. CAS No. 253168-86-4. Molecular Formula: C22H24N2O7S. Mole Weight: 460.5. Catalog: APB253168864. | |
| Apremilast Impurity 31 | Apremilast Impurity 31. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (E)-3,3'-(diazene-1,2-diyl)diphthalic acid. CAS No. 88687-92-7. Molecular Formula: C16H10N2O8. Mole Weight: 358.26. Catalog: APB88687927. | |
| Apremilast Impurity 32 | Apremilast Impurity 32. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3,3'-(hydrazine-1,2-diyl)diphthalic acid. Molecular Formula: C16H12N2O8. Mole Weight: 360.28. Catalog: APB02687. | |
| Apremilast Impurity 33 | Apremilast Impurity 33. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-1,2-bis(2,3-dicarboxyphenyl)diazene oxide. Molecular Formula: C16H10N2O9. Mole Weight: 374.26. Catalog: APB02686. | |
| Apremilast Impurity 34 | Apremilast Impurity 34. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-4-nitroisoindoline-1,3-dione. CAS No. 2095036-40-9. Molecular Formula: C20H20N2O8S. Mole Weight: 448.45. Catalog: APB2095036409. | |
| Apremilast Impurity 34 | Apremilast Impurity 34. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2469037-82-7. Molecular Formula: C20H20N2O7S. Mole Weight: 432.45. Catalog: APB2469037827. | |
| Apremilast Impurity 35 | Apremilast Impurity 35. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine. CAS No. 253168-94-4. Molecular Formula: C12H19NO4S. Mole Weight: 273.35. Catalog: APB253168944. | |
| Apremilast Impurity 36 | Apremilast Impurity 36. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-acetamidophthalic acid. CAS No. 15371-06-9. Molecular Formula: C10H9NO5. Mole Weight: 223.18. Catalog: APB15371069. | |
| Apremilast Impurity 37 | Apremilast Impurity 37. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(1,3-dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide. CAS No. 6296-53-3. Molecular Formula: C10H7NO4. Mole Weight: 205.17. Catalog: APB6296533. | |
| Apremilast Impurity 37 | Apremilast Impurity 37. Uses: For analytical and research use. Group: Impurity standards. CAS No. 67614-42-0. Molecular Formula: C10H9NO5. Mole Weight: 223.18. Catalog: APB67614420. | |
| Apremilast Impurity 38 | Apremilast Impurity 38. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N,N'-(2,2'-((propane-1,3-diyldisulfonyl)bis(1-(3-ethoxy-4-methoxyphenyl)ethane-2,1-diyl))bis(1,3-dioxoisoindoline-4,2-diyl))diacetamide. CAS No. 2487573-08-8. Molecular Formula: C45H48N4O14S2. Mole Weight: 933.01. Catalog: APB2487573088. | |
| Apremilast Impurity 39 | Apremilast Impurity 39. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N,N'-(2,2'-((propane-1,3-diyldisulfonyl)bis(2-(3-ethoxy-4-methoxyphenyl)ethane-2,1-diyl))bis(1,3-dioxoisoindoline-4,2-diyl))diacetamide. Molecular Formula: C45H48N4O14S2. Mole Weight: 933.01. Catalog: APB02685. | |
| Apremilast Impurity 40 | Apremilast Impurity 40. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethenamine. CAS No. 1450657-31-4. Molecular Formula: C12H17NO4S. Mole Weight: 271.33. Catalog: APB1450657314. | |
| Apremilast Impurity 41 | Apremilast Impurity 41. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (E)-1,2-bis(2,3-dicarboxyphenyl)diazene oxide. Molecular Formula: C16H10N2O9. Mole Weight: 374.26. Catalog: APB02684. | |
| Apremilast Impurity 42 | Apremilast Impurity 42. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-N-(2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-5-hydroxy-1,3-dioxoisoindolin-4-yl)acetamide. CAS No. 2096492-43-0. Molecular Formula: C22H24N2O8S. Mole Weight: 476.13. Catalog: APB2096492430. | |
| Apremilast Impurity 43 | Apremilast Impurity 43. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-amino-6-(ethoxycarbonyl)benzoic acid. CAS No. 208774-55-4. Molecular Formula: C10H11NO4. Mole Weight: 209.07. Catalog: APB208774554. | |
| Apremilast Impurity 44 | Apremilast Impurity 44. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-amino-2-(ethoxycarbonyl)benzoic acid. CAS No. 1822756-03-5. Molecular Formula: C10H11NO4. Mole Weight: 209.07. Catalog: APB1822756035. | |
| Apremilast Impurity 44 | Apremilast Impurity 44. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1258597-47-5. Molecular Formula: C22H19D5N2O7S. Mole Weight: 465.53. Catalog: APB1258597475. | |
| Apremilast Impurity 45 | Apremilast Impurity 45. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: diethyl 3-aminophthalate. CAS No. 62351-80-8. Molecular Formula: C12H15NO4. Mole Weight: 237.10. Catalog: APB62351808. | |
| Apremilast Impurity 46 | Apremilast Impurity 46. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-amino-6-(isopropoxycarbonyl)benzoic acid. Molecular Formula: C11H13NO4. Mole Weight: 223.08. Catalog: APB02683. | |
| Apremilast Impurity 47 | Apremilast Impurity 47. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-amino-2-(isopropoxycarbonyl)benzoic acid. Molecular Formula: C11H13NO4. Mole Weight: 223.08. Catalog: APB02682. | |
| Apremilast Impurity 48 | Apremilast Impurity 48. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: diisopropyl 3-aminophthalate. Molecular Formula: C14H19NO4. Mole Weight: 265.13. Catalog: APB02645. | |
| Apremilast Impurity 49 | Apremilast Impurity 49. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (E)-1-(3-ethoxy-4-methoxyphenyl)-2-((3-ethoxy-4-methoxystyryl)sulfonyl)ethanone. Molecular Formula: C22H26O7S. Mole Weight: 434.14. Catalog: APB02680. | |
| Apremilast Impurity 50 | Apremilast Impurity 50. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-2-((S)-2-acetamido-4-methylpentanamido)-4-methylpentanoic acid. Molecular Formula: C14H26N2O4. Mole Weight: 286.19. Catalog: APB02681. | |
| Apremilast Impurity 51 | Apremilast Impurity 51. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-2-((S)-2-acetamido-4-methylpentanamido)-4-methylpentanoic acid. Molecular Formula: C14H26N2O4. Mole Weight: 286.19. Catalog: APB02679. | |
| Apremilast Impurity 51 | Apremilast Impurity 51. Uses: For analytical and research use. Group: Impurity standards. CAS No. 247569-89-7. Molecular Formula: C10H13NO3. Mole Weight: 195.22. Catalog: APB247569897. | |
| Apremilast Impurity 53 | Apremilast Impurity 53. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-ethoxy-4-methoxybenzaldehyde. CAS No. 1131-52-8. Molecular Formula: C10H12O3. Mole Weight: 180.20. Catalog: APB1131528. | |
| Apremilast Impurity 54 | Apremilast Impurity 54. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3,4-diethoxybenzaldehyde. CAS No. 2029-94-9. Molecular Formula: C11H14O3. Mole Weight: 194.23. Catalog: APB2029949. | |
| Apremilast Impurity 55 | Apremilast Impurity 55. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanimine. Molecular Formula: C12H17NO4S. Mole Weight: 271.33. Catalog: APB01214. | |
| Apremilast Impurity 56 | Apremilast Impurity 56. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(3-ethoxy-4-methoxyphenyl)-2-((2-hydroxyethyl)sulfonyl)ethanone. Molecular Formula: C13H18O6S. Mole Weight: 302.34. Catalog: APB02678. | |
| Apremilast Impurity 57 | Apremilast Impurity 57. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-ethoxy-3-methoxybenzonitrile. CAS No. 81259-56-5. Molecular Formula: C10H11NO2. Mole Weight: 177.20. Catalog: APB81259565. | |
| Apremilast Impurity 57 | Apremilast Impurity 57. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2487573-01-1. Molecular Formula: C23H26N2O8S. Mole Weight: 490.53. Catalog: APB2487573011. | |
| Apremilast Impurity 58 | Apremilast Impurity 58. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3,4-diethoxybenzonitrile. CAS No. 60758-87-4. Molecular Formula: C11H13NO2. Mole Weight: 191.23. Catalog: APB60758874. | |
| Apremilast Impurity 58 | Apremilast Impurity 58. Uses: For analytical and research use. Group: Impurity standards. CAS No. 608142-27-4. Molecular Formula: C12H19NO4S. Mole Weight: 273.35. Catalog: APB608142274. | |
| Apremilast Impurity 59 | Apremilast Impurity 59. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3,4-dimethoxybenzonitrile. CAS No. 2024-83-1. Molecular Formula: C9H9NO2. Mole Weight: 163.17. Catalog: APB2024831. | |
| Apremilast Impurity 60 | Apremilast Impurity 60. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3,4-dihydroxybenzonitrile. CAS No. 17345-61-8. Molecular Formula: C7H5NO2. Mole Weight: 135.12. Catalog: APB17345618. | |
| Apremilast Impurity 61 | Apremilast Impurity 61. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-hydroxy-4-methoxybenzaldehyde. CAS No. 621-59-0. Molecular Formula: C8H8O3. Mole Weight: 152.15. Catalog: APB621590. | |
| Apremilast Impurity 62 | Apremilast Impurity 62. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-4-amino-2-(1-(3-hydroxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione. Molecular Formula: C18H18N2O6S. Mole Weight: 390.41. Catalog: APB02676. | |
| Apremilast Impurity 62 | Apremilast Impurity 62. Uses: For analytical and research use. Group: Impurity standards. CAS No. 608141-43-1. Molecular Formula: C20H34N2O7S. Mole Weight: 446.56. Catalog: APB608141431. | |
| Apremilast Impurity 63 | Apremilast Impurity 63. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (E)-2-ethoxy-1-methoxy-4-(2-(methylsulfonyl)vinyl)benzene. CAS No. 1831833-38-5. Molecular Formula: C12H16O4S. Mole Weight: 256.32. Catalog: APB1831833385. | |
| Apremilast Impurity 64 | Apremilast Impurity 64. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-ethoxy-4-(1-isopropoxy-2-(methylsulfonyl)ethyl)-1-methoxybenzene. Molecular Formula: C15H24O5S. Mole Weight: 316.41. Catalog: APB02677. | |
| Apremilast Impurity 65 | Apremilast Impurity 65. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine (S)-2-acetamido-4-methylpentanoate. Molecular Formula: C12H19NO4S·C8H15NO3. Mole Weight: 446.56. Catalog: APB02675. | |
| Apremilast Impurity 66 | Apremilast Impurity 66. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-N-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)acetamide. CAS No. 2097600-16-1. Molecular Formula: C14H21NO5S. Mole Weight: 315.39. Catalog: APB2097600161. | |
| Apremilast Impurity 66 | Apremilast Impurity 66. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2055542-18-0. Molecular Formula: C12H18O5S. Mole Weight: 274.33. Catalog: APB2055542180. | |
| Apremilast Impurity 67 | Apremilast Impurity 67. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(3-ethoxy-4,5-dimethoxyphenyl)-2-(methylsulfonyl)ethanone. Molecular Formula: C13H18O6S. Mole Weight: 302.34. Catalog: APB02673. | |
| Apremilast Impurity 68 | Apremilast Impurity 68. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2,2'-sulfonylbis(1-(3-ethoxy-4-methoxyphenyl)ethanone). Molecular Formula: C22H26O8S. Mole Weight: 450.50. Catalog: APB02672. | |
| Apremilast Impurity 68 | Apremilast Impurity 68. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1258597-45-3. Molecular Formula: C22H16D8N2O7S. Mole Weight: 468.55. Catalog: APB1258597453. | |
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