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| Product | Description | |
|---|---|---|
| Apremilast | Apremilast (CC-10004) is an orally available inhibitor of type-4 cyclic nucleotide phosphodiesterase ( PDE-4 ) with an IC 50 of 74 nM. Apremilast inhibits TNF-α release by lipopolysaccharide (LPS) with an IC 50 of 104 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CC-10004. CAS No. 608141-41-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12085. |  |
| Apremilast | Apremilast is an orally available small molecule inhibitor of phosphodiesterase 4 (PDE4). Apremilast specifically inhibits PDE4 and inhibits spontaneous production of TNF-alpha from human rheumatoid synovial cells. Uses: Anti-inflammatory agents, non-steroidal; phosphodiesterase inhibitors. Synonyms: (S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione; (S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide; CC 10004; CC10004; CC-10004. Grades: >98%. CAS No. 608141-41-9. Molecular formula: C22H24N2O7S. Mole weight: 460.50. |  |
| Apremilast Dimer | Apremilast Dimer is an impurity of Apremilast, which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. Synonyms: (S)-N-(2'-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,1',3,3'-tetraoxo-[2,4'-biisoindolin]-4-yl)acetamide. CAS No. 1802246-60-1. Molecular formula: C30H27N3O9S. Mole weight: 605.6. | |
| Apremilast Impurity 18 | Apremilast Impurity 18. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1407140-51-5. Molecular formula: C20H32N2O6S. Mole weight: 428.54. Catalog: APB1407140515. |  |
| Apremilast Impurity 2 | A metabolite of Apremilast. Synonyms: (R)-Apremilast; N-[2-[(1R)?-1-(3-Ethoxy-4-methoxyphenyl)?-2-(methylsulfonyl)?ethyl]?-2,?3-dihydro-1,?3-dioxo-1H-isoindol-4-yl]?-acetamide. Grades: > 95%. CAS No. 608141-44-2. Molecular formula: C22H24N2O7S. Mole weight: 460.51. | |
| Apremilast Impurity 22 | Apremilast Impurity 22. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-nitrosophthalic acid. CAS No. 106860-70-2. Molecular formula: C8H5NO5. Mole weight: 195.13. Catalog: APB106860702. | |
| Apremilast Impurity 36 | Apremilast Impurity 36. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-acetamidophthalic acid. CAS No. 15371-06-9. Molecular formula: C10H9NO5. Mole weight: 223.18. Catalog: APB15371069. | |
| Apremilast Impurity 53 | Apremilast Impurity 53. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-ethoxy-4-methoxybenzaldehyde. CAS No. 1131-52-8. Molecular formula: C10H12O3. Mole weight: 180.20. Catalog: APB1131528. | |
| Apremilast Impurity 86 | Apremilast Impurity 86. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1852533-96-0. Molecular formula: C8H12ClNO6. Mole weight: 253.64. Catalog: APB1852533960. | |
| Apremilast Impurity B | Apremilast Impurity B. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(3,4-dimethoxyphenyl)-2-(methylsulfonyl)ethanamine. CAS No. 1255909-25-1. Molecular formula: C11H17NO4S. Mole weight: 259.32. Catalog: APB1255909251. | |
| (+/-)-Apremilast | (+/-)-Apremilast is the racemic form of Apremilast, an orally available small molecule inhibitor of phosphodiesterase 4 (PDE4). Synonyms: Apremilast, (+/-)-; N-(2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide; Acetamide, N-(2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl)-. CAS No. 253168-86-4. Molecular formula: C22H24N2O7S. Mole weight: 460.5. | |
| Des-acetyl Apremilast | Des-acetyl Apremilast is an impurity of Apremilast, which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. Synonyms: 4-Amino-2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1H-isoindole-1,3(2H)-dione; (S)-4-amino-2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione. CAS No. 635705-72-5. Molecular formula: C20H22N2O6S. Mole weight: 418.46. | |
| N-Desacetyl-N-formyl Apremilast | N-Desacetyl-N-formyl Apremilast is an impurity of Apremilast, which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. Synonyms: (S)-N-(2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)formamide; N-{2-[(1S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}formamide. CAS No. 2077897-94-8. Molecular formula: C21H22N2O7S. Mole weight: 446.47. | |
| 1- (3-Ethoxy-4-methoxy-phenyl) -2-methane sulfonylethylamine | 1- (3-Ethoxy-4-methoxy-phenyl) -2-methane sulfonylethylamine is used in the enantioselective synthesis of Apremilast (A729700) aminosulfone using catalytic asymetric hydrogenation. Apremilast EP Impurity H. Group: Biochemicals. Grades: Highly Purified. CAS No. 253168-94-4. Pack Sizes: 250mg, 1g. Molecular Formula: C12H19NO4S, Molecular Weight: 273.35. US Biological Life Sciences. |  Worldwide |
| (1S)-1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethylamine | (1S)-1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethylamine is an Apremilast (A729700) intermediate. Apremilast, an oral phosphodiesterase 4 inhibitor is used in the treatment of psoriatic arthritis. Group: Biochemicals. Grades: Highly Purified. CAS No. 608141-42-0. Pack Sizes: 1mg, 5mg. Molecular Formula: C12H19NO4S. US Biological Life Sciences. | Worldwide |
| 2- (Acetylamino) -6-[[[ (1S) -1- (3-ethoxy-4-methoxyphenyl) -2- (methylsulfonyl) ethyl]amino]carbonyl]-benzoic Acid | 2- (Acetylamino) -6-[[[ (1S) -1- (3-ethoxy-4-methoxyphenyl) -2- (methylsulfonyl) ethyl]amino]carbonyl]-benzoic Acid is an impurity of Apremilast (A729700), which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1809170-71-5. Pack Sizes: 10mg, 100mg. Molecular Formula: C22H26N2O8S. US Biological Life Sciences. | Worldwide |
| (2S,3S,4S,5R,6S)-6-(5-((R)-1-(4-Acetamido-1,3-dioxoisoindolin-2-yl)-2-(methylsulfonyl)ethyl)-2-ethoxyphenoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid | (2S,3S,4S,5R,6S)-6-(5-((R)-1-(4-Acetamido-1,3-dioxoisoindolin-2-yl)-2-(methylsulfonyl)ethyl)-2-ethoxyphenoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid is a related compound of Apremilast (A729700), which is an oral phosphodiesterase 4 inhibitor used in the treatment of psoriatic arthritis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C27H30N2O13S, Molecular Weight: 622.6. US Biological Life Sciences. | Worldwide |
| 3-acetamidophthalic acid | Apremilast Impurity 18 is an impurity of Apremilast, which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. Synonyms: 3-(Acetylamino)phthalic acid; 3-(Acetylamino)-1,2-benzenedicarboxylic Acid; 1,2-Benzenedicarboxylic acid, 3-(acetylamino)-. CAS No. 15371-06-9. Molecular formula: C10H9NO5. Mole weight: 223.18. | |
| 3-Acetamidophthalic Acid | 3-Acetamidophthalic Acid is an impurity of Apremilast (A729700); an oral phosphodiesterase 4 inhibitor used in the treatment of psoriatic arthritis. Apremilast EP Impurity B. Group: Biochemicals. Grades: Highly Purified. CAS No. 15371-06-9. Pack Sizes: 5mg, 25mg. Molecular Formula: C10H9NO5. US Biological Life Sciences. | Worldwide |
| 3-(Acetylamino)-1,2-benzenedicarboxylic Acid Methyl Ester | 3-(Acetylamino)-1,2-benzenedicarboxylic Acid Methyl Ester α S) -3-Ethoxy-4-methoxy-α -[ (methylsulfonyl) methyl]-N-[ (1S) -1-phenylethyl]-benzenemethanamine which is an impurity of Apremilast (A729700), which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. Group: Biochemicals. Grades: Highly Purified. CAS No. 144841-10-1. Pack Sizes: 5mg, 10mg. Molecular Formula: C11H11NO5. US Biological Life Sciences. | Worldwide |
| 3-Acetylaminophthalic Anhydride | 3-Acetylaminophthalic Anhydride is used in the synthesis of Apremilast, a potent phosphodiesterase 4 and tumor necrosis Factor-α inhibitor used in the treatment of psoriatic arthritis. Also a reagent in the preparation of Tillivalline. Apremilast Impurity 2. Group: Biochemicals. Grades: Highly Purified. CAS No. 6296-53-3. Pack Sizes: 1g, 10g. Molecular Formula: C10H7NO4, Molecular Weight: 205.17. US Biological Life Sciences. | Worldwide |
| (E)-2-ethoxy-1-methoxy-4-(2-(methylsulfonyl)vinyl)benzene | (E)-2-ethoxy-1-methoxy-4-(2-(methylsulfonyl)vinyl)benzene is an impurity of Apremilast, which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. Synonyms: 1831833-38-5; 2-Ethoxy-1-methoxy-4-(2-methylsulfonylethenyl)benzene; DS-018767. Grades: 95%. CAS No. 1831833-38-5. Molecular formula: C12H16O4S. Mole weight: 256.32. | |
| N-(1,3-dioxoisoindolin-4-yl)acetamide | N-(1,3-dioxoisoindolin-4-yl)acetamide is an impurity of Apremilast, which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. Synonyms: 3-Acetamidophthalimide; N-(1,3-dioxo-4-isoindolyl)acetamide. CAS No. 6118-65-6. Molecular formula: C10H8N2O3. Mole weight: 204.18. | |
| (S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione | (S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione. Group: Biochemicals. Alternative Names: Apremilast. Grades: Highly Purified. CAS No. 608141-41-9. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C22H24N2O7. US Biological Life Sciences. | Worldwide |
| (S)-2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione | (S)-2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione is an impurity of Apremilast, which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. CAS No. 2077897-93-7. Molecular formula: C20H21NO6S. Mole weight: 403.45. | |
| (S) -2-acetamido-6- ( (1- (3-ethoxy-4-methoxyphenyl) -2- (methylsulfonyl) ethyl) carbamoyl) benzoic acid | (S) -2-acetamido-6- ( (1- (3-ethoxy-4-methoxyphenyl) -2- (methylsulfonyl) ethyl) carbamoyl) benzoic acid is an impurity of Apremilast, which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. Synonyms: 2-Acetamido-6-{[ (1S) -1- (3-ethoxy-4-methoxyphenyl) -2- (methylsulfonyl) ethyl]carbamoyl}benzoic acid. CAS No. 1809170-71-5. Molecular formula: C22H26N2O8S. Mole weight: 478.52. | |
| (S) -3-acetamido-2- ( (1- (3-ethoxy-4-methoxyphenyl) -2- (methylsulfonyl) ethyl) carbamoyl) benzoic acid | (S) -3-acetamido-2- ( (1- (3-ethoxy-4-methoxyphenyl) -2- (methylsulfonyl) ethyl) carbamoyl) benzoic acid is an impurity of Apremilast, which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. Synonyms: 3-Acetamido-2-{[ (1S) -1- (3-ethoxy-4-methoxyphenyl) -2- (methylsulfonyl) ethyl]carbamoyl}benzoic acid. CAS No. 2096492-41-8. Molecular formula: C22H26N2O8S. Mole weight: 478.52. | |
| (S)-N-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)acetamide | (S)-N-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)acetamide is an impurity of Apremilast, which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. Synonyms: (S)-N-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)acetamide; SCHEMBL15198848; 2097600-16-1. CAS No. 2097600-16-1. Molecular formula: C14H21NO5S. Mole weight: 315.38. | |
| (S)-N-(2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-5-yl)acetamide | (S)-N-(2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-5-yl)acetamide is an impurity of Apremilast, which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. CAS No. 2201974-01-6. Molecular formula: C22H24N2O7S. Mole weight: 460.50. | |
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