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100mg Pack Size. Group: Analytical Reagents, Biochemicals, Building Blocks. Formula: CH3(CH2)4(CH=CHCH2)4CH2CH2CO2H. CAS No. 506-32-1. Prepack ID 89988669-100mg. Molecular Weight 304.47. See USA prepack pricing.
Arachidonicacid
Arachidonicacid (Immunocytophyt) is a polyunsaturated omega-6 fatty acid and a major constituent of biomembranes. Arachidonicacid also acts as the substrate for various lipid mediators, such as prostaglandins (PGs). Arachidonicacid improves cognitive response and cardiovascular function [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Immunocytophyt. CAS No. 506-32-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-109590.
Arachidonicacid
Arachidonicacid is an essential fatty acid and a precursor in the biosynthesis of thromboxanes, prostaglandins and leukotrienes. It is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. It is an important cellular signaling mediator in a variety of biological processes, including smooth chemotaxis, muscle contraction, apoptosis, cell proliferation and differentiation. It exits in liver, brain, glandular organs, and depot fats of animals and a constituent of animal phosphatides. It could bind to the subunit of G protein and inhibit the activity of Ras GTPase-activating proteins (GAPs). It stimulates adhesion of MDA-MB-435 human metastatic cancer cells to extracellular matrix molecules. Synonyms: Arachidonate. Grades: 98 %. CAS No. 506-32-1. Molecular formula: C20H32O2. Mole weight: 304.47.
ArachidonicAcid 10%
ArachidonicAcid 10%.
CA, FL & NJ
Arachidonicacid-[13C20]
Labelled Arachidonicacid. Arachidonicacid is an essential fatty acid and a precursor in the biosynthesis of thromboxanes, prostaglandins and leukotrienes. It is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. It is an important cellular signaling mediator in a variety of biological processes, including smooth chemotaxis, muscle contraction, apoptosis, cell proliferation and differentiation. It exits in liver, brain, glandular organs, and depot fats of animals and a constituent of animal phosphatides. It could bind to the subunit of G protein and inhibit the activity of Ras GTPase-activating proteins (GAPs). It stimulates adhesion of MDA-MB-435 human metastatic cancer cells to extracellular matrix molecules. Grades: > 98%. Molecular formula: [13C]20H32O2. Mole weight: 324.32.
ArachidonicAcid, >97%
ArachidonicAcid, >97%. Uses: For analytical and research use. Group: Mycotoxins; building blocks. Alternative Names: Arachidonicacid,5,8,11,14-Eicosatetraenoic acid, (all-Z)- (8CI), 5,8,11,14-all-cis-Eicosatetraenoic acid, (5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenoic acid, all-cis-5,8,11,14-Eicosatetraenoic acid, (all-Z)-5,8,11,14-Eicosatetraenoic acid, cis-Δ5,8,11,14-Eicosatetraenoic acid, Vevodar, Immunocytophyt, 20:4n-6, 5-cis,8-cis,11-cis,14-cis-Eicosatetraenoic acid, 5Z,8Z,11Z,14Z-Eicosatetraenoic acid, A 0871, Immunocytophyte. CAS No. 506-32-1. Pack Sizes: 10MG. IUPAC Name: (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid. Molecular Formula: C20H32O2. Mole Weight: 304.47. Catalog: APS506321. SMILES: CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC (=O)O. Format: Neat. Shipping: Dry ice.
arachidonicacid-alkyne
arachidonicacid-alkyne is a modified lipid containing omega terminal alkynes. Synonyms: 5Z,8Z,11Z,14Z-eicosatetraen-19-ynoic acid. Grades: >99%. CAS No. 1219038-32-0. Molecular formula: C20H28O2. Mole weight: 300.44.
ArachidonicAcid Alkyne
ArachidonicAcid Alkyne. CAS No. 1219038-32-0. Catalog: ACM1219038320.
ArachidonicAcid Alkyne
ArachidonicAcid Alkyne is a metabolite of ArachidonicAcid (A3303). ArachidonicAcid is an essential fatty acid and a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. ArachidonicAcid occurs in liver, brain, glandular organs, and depot fats of animals, in small amounts in human depot fats, and ArachidonicAcid is also a constituent of animal phosphatides. Group: Biochemicals. Grades: Highly Purified. CAS No. 1219038-32-0. Pack Sizes: 100ug, 500ug. Molecular Formula: C20H28O2, Molecular Weight: 300.44. US Biological Life Sciences.
Worldwide
ArachidonicAcid-biotinamide
ArachidonicAcid-biotinamide. CAS No. 1217901-28-4. Catalog: ACM1217901284.
Arachidonicacid-d11
Arachidonicacid-d 11 is the deuterium labeled Arachidonicacid. Arachidonicacid is an essential fatty acid and a major constituent of biomembranes[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Immunocytophyt-d11. CAS No. 2692624-11-4. Pack Sizes: 100 μg (3.17 mM * 100 μL in Ethanol). Product ID: HY-109590S2.
Arachidonicacid-d8
Arachidonicacid-d 8 is the deuterium labeled Arachidonicacid. Arachidonicacid is an essential fatty acid and a major constituent of biomembranes[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Immunocytophyt-d8. CAS No. 69254-37-1. Pack Sizes: 1 mg (32.00 mM * 100 μL in Methyl acetate). Product ID: HY-109590S.
arachidonicacid-EDTA
arachidonicacid-EDTA. CAS No. 105028-29-3. Catalog: ACM105028293.
Arachidonicacid (Immunocytophyt) sodium salt is a polyunsaturated omega-6 fatty acid and a major constituent of biomembranes. Arachidonicacid sodium salt also acts as the substrate for various lipid mediators, such as prostaglandins (PGs). Arachidonicacid sodium salt improves cognitive response and cardiovascular function [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Immunocytophyt sodium salt. CAS No. 6610-25-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-109590A.
Arachidonicacid (Standard)
Arachidonicacid (Immunocytophyt) (Standard) is the analytical standard of Arachidonicacid (HY-109590). This product is intended for research and analytical applications. Arachidonicacid is an essential fatty acid and a major constituent of biomembranes. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Immunocytophyt (Standard). CAS No. 506-32-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109590R.
20-carboxy ArachidonicAcid
20-carboxy ArachidonicAcid is a PPARα and PPARγ activator. Group: Biochemicals. Grades: Highly Purified. CAS No. 79551-84-1. Pack Sizes: 25ug, 50ug. Molecular Formula: C20H30O4, Molecular Weight: 334.45. US Biological Life Sciences.
Worldwide
20-Carboxy arachidonicacid
20-Carboxy arachidonicacid (20-COOH-AA) is the major metabolite of 20-HETE that is produced in renal tubular epithelial, endothelial, and microvascular smooth muscle cell cultures. This ω-oxidation conversion can take place using purified alcohol dehydrogenases three and four or by microsomes containing recombinant human CYP4F3B. Synonyms: 20-carboxy AA; 20-COOH-AA; 5Z,8Z,11Z,14Z-Eicosatetraenedioic acid; Arachidonicacid-20-carboxylic acid. Grades: >98%. CAS No. 79551-84-1. Molecular formula: C20H30O4. Mole weight: 334.5.
5,6-Dehydro arachidonicacid
5,6-Dehydro arachidonicacid is an analog of arachidonicacid with an acetylene in the 5,6 position. Synonyms: 5,6-dehydro AA; 8Z,1Z1,14Z-Eicosatrien-5-ynoic acid. Grades: ≥98%. CAS No. 58688-54-3. Molecular formula: C20H30O2. Mole weight: 302.5.
11(R)-HETE is a kind of arachidonicacid [1]. Uses: Scientific research. Group: Natural products. CAS No. 73347-43-0. Pack Sizes: 100 μg (312.04 μM * 1 mL in Ethanol). Product ID: HY-113453.
12-HETE
12-HETE, a major metabolic product of arachidonicacid using 12-LOX catalysis, inhibits cell apoptosis in a dose-dependent manner. 12-HETE promotes the activation and nuclear translocation of NF-κB through the integrin-linked kinase (ILK) pathway [1].12-HETE has both anti-thrombotic and pro-thrombotic effects [2]. 12-HETE is a neuromodulator [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 71030-37-0. Pack Sizes: 50 μg (312.04 μM * 0.5 mL in Ethanol); 100 μg (312.04 μM * 1 mL in Ethanol). Product ID: HY-113439.
(+/-)12-HpETE
(+/-)12-HpETE is one of the six monohydroperoxy fatty acids and metabolite of arachidonicacid. Group: Biochemicals. Alternative Names: 12-hydroperoxy-5Z,8Z,10E,14Z-eicosatetraenoic acid. Grades: Highly Purified. CAS No. 71030-35-8. Pack Sizes: 25ug, 50ug, 100ug. Molecular Formula: C20H32O4, Molecular Weight: 336.47. US Biological Life Sciences.
Worldwide
12(R)-HETE
12(R)-HETE is a metabolite of Arachidonicacid, AA (HY-109590) and can be found in skin from psoriatic lesions. 12(R)-HETE induces lymphocytes chemotaxis, stimulates calcium mobilization and chemotaxis in neutrophils via the BLT1 receptor, activates the aryl hydrocarbon receptor, and inhibits Na+/K+ ATPase activity in the corneal epithelium [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 82337-46-0. Pack Sizes: 5 μg (312.04 μM * 50 μL in Ethanol); 10 μg (312.04 μM * 100 μL in Ethanol); 25 μg (312.04 μM * 250 μL in Ethanol); 50 μg (312.04 μM * 500 μL in Ethanol). Product ID: HY-124404.
12(S),20-DiHETE
12(S),20-DiHETE is an arachidonicacid metabolite which engages in transcellular biosynthesis. Group: Biochemicals. Grades: Highly Purified. CAS No. 89614-44-8. Pack Sizes: 50ug, 100ug. Molecular Formula: C20H32O4, Molecular Weight: 336.47. US Biological Life Sciences.
Worldwide
12(S)-HETE
12(S)-HETE is the 12-lipoxygenase metabolite of arachidonicacid and has a mitogenic effect on cancer cell proliferation. 12(S)-HETE induces tyrosine phosphorylation of cellular proteins, promotes ERK and P38 MAPK phosphorylation, increases DNA synthesis, and stimulates the proliferation of pancreatic cancer cells [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 54397-83-0. Pack Sizes: 100 μg (312.04 μM * 1 mL in Ethanol). Product ID: HY-124404A.
12(S)-HHTrE
12(S)-HHTrE is a metabolite of arachidonicacid (A3303), which is an essential fatty acid and a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. ArachidonicAcid occurs in liver, brain, glandular organs, and depot fats of animals, in small amounts in human depot fats, and ArachidonicAcid is also a constituent of animal phosphatides. Group: Biochemicals. Grades: Highly Purified. CAS No. 54397-84-1. Pack Sizes: 500ug, 5mg. Molecular Formula: C17H28O3, Molecular Weight: 280.399999999999. US Biological Life Sciences.
Worldwide
12(S)-HHTrE
12(S)-HHTrE is a product of the cyclooxygenase (COX) pathway and one of the primary arachidonicacid metabolites of human platelets. It is biosynthesized by thromboxane (TXA2) synthase from prostaglandin H2 (PGH2) concurrently with TXA2. Synonyms: 12(S)-HHT; 12-hydroxyheptadecatrienoic acid. Grades: ≥95%. CAS No. 54397-84-1. Molecular formula: C17H28O3. Mole weight: 280.4.
12(S)-HpETE
12(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of platelet or leukocyte 12-lipoxygenase (12-LO) on arachidonicacid. It mediates the inhibitory synaptic response to FMRF-amide in Aplysia sensory neurons6 and inhibits Ca2+/calmodulin-dependent protein kinase II from rat brain cortex. Synonyms: 12-Hydroperoxyicosatetraenoate; (5Z,8Z,10E,12S,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoic acid. Grades: ≥98%. CAS No. 71774-10-2. Molecular formula: C20H32O4. Mole weight: 336.5.
14,15-Dehydro leukotriene B4
14,15-Dehydro leukotriene B4 is a dihydroxy fatty acid derived from arachidonicacid through the 5-lipoxygenase pathway. Synonyms: 14,15-dehydro LTB4; 5S,12R-dihydroxy-6Z,8E,10E-eicosatrien-14-ynoic acid. Grades: ≥97%. CAS No. 114616-11-4. Molecular formula: C20H30O4. Mole weight: 334.5.
(±)14,15-Epoxyeicosatrienoic acid
(±)14,15-Epoxyeicosatrienoic acid ((±)14(15)-EET) is the Cytochrome P450 metabolite of arachidonicacid. While CYP3A4 may be involved in breast cancer cell growth, (±)14,15-Epoxyeicosatrienoic acid may promote mitosis and anchorage-dependent cloning through STAT3 affected by CYP3A4. (±)14,15-Epoxyeicosatrienoic acid exhibits STAT3-dependent cell growth promotion and may also participate in the autocrine/paracrine pathway that drives cell growth [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (±)14(15)-EET. CAS No. 197508-62-6. Pack Sizes: 50 μg (312.04 μM * 500 μL in Ethanol). Product ID: HY-150084.
14,15-Epoxyeicosatrienoic Acid (±14,15-EET)
Epoxyeicosatrienoic Acid (EET) has antihypertensive and anti-inflammatory properties and play a role in the maintenance of renal vascular function. N,?N'-?dicyclohexylurea (DCU) increased release of 14,15-EET when the cells were stimulated with a calcium ionophore. Also, it is derived from ArachidonicAcid, which is an essential fatty acid and a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. ArachidonicAcid occurs in liver, brain, glandular organs, and depot fats of animals, in small amounts in human depot fats, and ArachidonicAcid is also a constituent of animal phosphatides. Group: Biochemicals. Alternative Names: (5Z,8Z,11Z)-13-(3-Pentyl-2-oxiranyl)-5,8,11-tridecatrienoic Acid; 14(15)-EET; 14(15)-Epoxy-5Z,8Z,11Z-eicosatrienoic Acid; (±)14,15-EET; (±)14,15-EpETrE; (all-Z)-13-(3-Pentyloxiranyl)-5,8,11-tridecatrienoic Acid. Grades: Highly Purified. CAS No. 197508-62-6. Pack Sizes: 50ug, 100ug, 500ug. Molecular Formula: C??H??O?, Molecular Weight: 320.47. US Biological Life Sciences.
Worldwide
15-hydroxyicosatetraenoate dehydrogenase
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate:NAD(P)+ 15-oxidoreductase. This enzyme is also called 15-hydroxyeicosatetraenoate dehydrogenase. This enzyme participates in arachidonicacid metabolism. Group: Enzymes. Synonyms: 15-hydroxyeicosatetraenoate dehydrogenase. Enzyme Commission Number: EC 1.1.1.232. CAS No. 117910-46-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0139; 15-hydroxyicosatetraenoate dehydrogenase; EC 1.1.1.232; 117910-46-0; 15-hydroxyeicosatetraenoate dehydrogenase. Cat No: EXWM-0139.
15-KETE (15-oxo-ETE)
15-KETE (15-oxo-ETE) is a major metabolite of arachidonicacid that is formed through the Lipoxygenase pathway. Group: Biochemicals. Grades: Highly Purified. CAS No. 81416-72-0. Pack Sizes: 50ug, 100ug. Molecular Formula: C20H30O3, Molecular Weight: 318.45. US Biological Life Sciences.
Worldwide
15-Keto Prostaglandin E2
15-Keto Prostaglandin E2 is a lipid compound derived from arachidonicacid by the action of cyclooxygenases. Prostaglandins act locally as messenger molecules in a variety of physiological processes. Group: Biochemicals. Grades: Highly Purified. CAS No. 26441-05-4. Pack Sizes: 10mg, 25mg. Molecular Formula: C20H30O5, Molecular Weight: 350.45. US Biological Life Sciences.
Worldwide
15-Lipoxygenase-2 from human, Recombinant
Two types of 15-lipoxygenase (15-LO) have been discovered and characterized, both of which metabolize arachidonicacid (AA) to produce 15(S)-hydroxyeicosatetraenoic acid (15(S)-HETE). 15-LO-1 oxygenates AA at both C-15 and C-12, whereas 15-LO-2 exclusively oxygenates C-15 of AA. Human 15-LO-2 has a molecular mass of approximately 76 kDa and exhibits approximately 40% identity to the reticulocyte 15-LO-1. Expression of 15-LO-2 appears to be restricted to prostate, lung, skin, and cornea and may play a role in the normal development of these tissues. The protein levels and enzymatic activity of 15-LO-2 are both down-regulated in prostate cancer compared with normal and benign prostate tissues, implicating a possible protective role for 15-LO-2 against tumor formation. Group: Enzymes. Synonyms: Arachidonate 15-lipoxygenase type II; 15-lipoxygenase-2; 15-LO-2; 15-LOX-2; ALOX15B. Enzyme Commission Number: EC 1.13.11.33. Purity: > 95% estimated by SDS-PAGE. Lipoxygenase. Mole weight: 76 kDa. Activity: 234.15 U/ml. Stability: As supplied, 6 months from the QC date provided on the Certificate of Analysis, when stored properly. Storage: at -80°C. Form: PBS, pH 7.4, 1 mM DTT and 20% glycerol. Source: E. coli. Species: Human. Arachidonate 15-lipoxygenase type II; 15-lipoxygenase-2; 15-LO-2; 15-LOX-2; ALOX15B. Cat No: NATE-1248.
15(R)-HETE
15(R)-HETE is an isomer of 15-HETE. 15-HETE is a lipid mediator derived from arachidonicacid and can be used for the study of asthma [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 83603-31-0. Pack Sizes: 25 μg (312.04 μM * 250 μL in Ethanol); 50 μg (312.04 μM * 500 μL in Ethanol); 100 μg (312.04 μM * 1 mL in Ethanol). Product ID: HY-113336A.
15(S)-HETE
15(S)-HETE is an arachidonicacid metabolite with immunosuppressive activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 54845-95-3. Pack Sizes: 50ug, 100ug. Molecular Formula: C20H32O3, Molecular Weight: 320.47. US Biological Life Sciences.
Worldwide
15(S)-HpETE
15(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonicacid. Synonyms: (S)-15-hpete; 15-Hydroperoxyicosatetraenoate; 15-Hydroperoxyeicosatetraenoate. Grades: ≥98%. CAS No. 70981-96-3. Molecular formula: C20H32O4. Mole weight: 336.5.
15(S)-HPETE
15(S)-HPETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonicacid. It is either metabolized to 14,15-leukotriene A41 or reduced to 15(S)-HETE by peroxidases.2,1 15(S)-HpETE mediates a number of biological functions including the induction of c-fos and c-jun, and activation of AP-1.3 15(S)-HpETE inhibits prostacyclin synthesis in porcine aortic microsomes and bovine endothelial cells, and can cause the suicide inactivation of porcine 12-LO. Uses: Scientific research. Group: Signaling pathways. CAS No. 70981-96-3. Pack Sizes: 25 μg (297.20 μM * 250 μL in Ethanol). Product ID: HY-113438.
15(S)-HPETE
15(S)-HPETE is a primary metabolite of arachidonicacid shown to inhibit arachidonicacid induced platelet aggregation. Group: Biochemicals. Grades: Highly Purified. CAS No. 70981-96-3. Pack Sizes: 50ug, 100ug. Molecular Formula: C20H32O4, Molecular Weight: 336.47. US Biological Life Sciences.
Worldwide
(±)16-HETE
Electrolyte and fluid transport in the kidney are regulated in part by arachidonicacid and its metabolites. Synonyms: 5,8,11,14-Eicosatetraenoicacid, 16-hydroxy-, (5Z,8Z,11Z,14Z)-. Grades: ≥98%. CAS No. 128914-46-5. Molecular formula: C20H32O3. Mole weight: 320.5.
16(R)-HETE
16-HETE is a minor CYP450 metabolite of arachidonicacid released by the kidney upon angiotensin II stimulation that demonstrates stereospecific biological activity. Synonyms: 16R-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid; (5Z,8Z,11Z,14Z)-(16R)-16-Hydroxyeicosa-5,8,11,14-tetraenoic acid. Grades: ≥98%. CAS No. 183509-22-0. Molecular formula: C20H32O3. Mole weight: 320.5.
16(S)-HETE
16-HETE is a minor CYP450 metabolite of arachidonicacid released by the kidney upon angiotensin II stimulation that demonstrates stereospecific biological activity. Synonyms: (16S)-hydroxyarachidonicacid; (5Z,8Z,11Z,14Z,16S)-16-hydroxyicosa-5,8,11,14-tetraenoic acid. Grades: ≥98%. CAS No. 183509-23-1. Molecular formula: C20H32O3. Mole weight: 320.5.
16(S)-HETE
16(S)-HETE is an arachidonicacid metabolite with stereospecific biological activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 183509-23-1. Pack Sizes: 25ug, 50ug. Molecular Formula: C20H32O3, Molecular Weight: 320.47. US Biological Life Sciences.
Worldwide
(±)17-HETE
Electrolyte and fluid transport in the kidney are regulated in part by arachidonicacid and its metabolites. (±)17-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonicacid that has stereospecific effects on sodium transport in the kidney. Synonyms: 17-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid; (5Z,8Z,11Z,14Z)-17-hydroxyicosa-5,8,11,14-tetraenoic Acid; 17-hydroxyeicosa-all-cis-5,8,11,14-tetraenoic acid. Grades: ≥98%. CAS No. 128914-47-6. Molecular formula: C20H32O3. Mole weight: 320.5.
17-ODYA
17-ODYA is a CYP450 ω-hydroxylase inhibitor. 17-ODYA is also a potent inhibitor (IC 50 <100 nM) of the formation of 20-hydroxyeicosatetraenoic acid (20-HETE), epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids by rat renal cortical microsomes incubated with arachidonicacid. 17-ODYA completely attenuates the isoproterenol (ISO)-induced apoptosis, and necrosis in cultured cardiomyocytes [1] [2] [3]. 17-ODYA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 34450-18-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-101016.
17(R)-HETE
17-HETE is a cytochrome P450 (CYP450) metabolite of arachidonicacid that has stereospecific effects on sodium transport in the kidney. Synonyms: (5Z,8Z,11Z,14Z,17R)-17-hydroxyicosa-5,8,11,14-tetraenoic acid. Grades: ≥98%. CAS No. 183509-24-2. Molecular formula: C20H32O3. Mole weight: 320.5.
17(S)-HETE
17-HETE is a cytochrome P450 (CYP450) metabolite of arachidonicacid that has stereospecific effects on sodium transport in the kidney.17(S)-HETE inhibits proximal tubule ATPase activity by as much as 70% at a concentration of 2 μM. Synonyms: 17-hydroxyicosa-5,8,11,14-tetraenoic acid. Grades: ≥98%. CAS No. 183509-25-3. Molecular formula: C20H32O3. Mole weight: 320.5.
17(S)-HETE
17(S)-HETE is a cytochrome P450 (CYP450) metabolite of arachidonicacid. Group: Biochemicals. Grades: Highly Purified. CAS No. 183509-25-3. Pack Sizes: 25ug, 50ug. Molecular Formula: C20H32O3, Molecular Weight: 320.47. US Biological Life Sciences.
Worldwide
1-Aminobenzotriazole
1-Aminobenzotriazole is a cytochrome P450 inhibitor that acts as a suicide substrate of CYP. It exhibits an inhibitory effect on oxidative drug metabolism and suppresses ω-oxidation of arachidonicacid devoid of epoxidation. Synonyms: 1H-Benzotriazol-1-amine; Benzotriazol-1-amine; ABT. Grades: ≥98% by HPLC. CAS No. 1614-12-6. Molecular formula: C6H6N4. Mole weight: 134.14.
1-Arachidonoyl glycerol
The glyceryl esters of arachidonicacid have been proposed as endogenous cannabinoid ligands. 2-AG is 10 to 100 times more potent than 1-AG in ligand binding affinity and agonist activity at the CB1 receptor, and is thus considered to be the natural ligand. Synonyms: 1-AG; glyceryl 1-arachidonate. Grades: ≥95%. CAS No. 35474-99-8. Molecular formula: C23H38O4. Mole weight: 378.6.
1-(Benzo[b]thien-2-yl)ethanol
1-(Benzo[b]thien-2-yl)ethanol is an intermediate used to prepare amino sugar and related sugar derivatives of indolopyrrolocarbazole s as antitumors. It is also an impurity of Zileuton (Z420000), an inhibitor of 5-lipoxygenase, the initial enzyme in the biosynthesis of leukotrienes from ArachidonicAcid. Zileuton is used as an antiasthmatic. Group: Biochemicals. Grades: Highly Purified. CAS No. 51868-95-2. Pack Sizes: 5mg, 25mg. Molecular Formula: C10H10OS, Molecular Weight: 178.25. US Biological Life Sciences.
Worldwide
1-Bromo-2,5,8,11,14,17,20-tricosaheptayne
1-Bromo-2,5,8,11,14,17,20-tricosaheptayne is an unsaturated compound that is related to Arachidonicacid (A3303). Arachidonicacid is membrane phospholipid component of mammalian cells that is known to give the cell membranes their correct fluidity. Arachidonicacid also directly activates potassium channels in smooth muscle. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C23H19Br, Molecular Weight: 375.3. US Biological Life Sciences.
Worldwide
1-Bromo-2,5,8,11,14,17-icosahexayne
1-Bromo-2,5,8,11,14,17-icosahexayne is an unsaturated compound that is related to Arachidonicacid (A3303). Arachidonicacid is membrane phospholipid component of mammalian cells that is known to give the cell membranes their correct fluidity. Arachidonicacid also directly activates potassium channels in smooth muscle. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C20H17Br, Molecular Weight: 337.25. US Biological Life Sciences.
Worldwide
1-Bromo-2,5,8,11,14-heptadecapentayne
1-Bromo-2,5,8,11,14-heptadecapentayne is an unsaturated compound that is related to Arachidonicacid (A3303). Arachidonicacid is membrane phospholipid component of mammalian cells that is known to give the cell membranes their correct fluidity. Arachidonicacid also directly activates potassium channels in smooth muscle. Group: Biochemicals. Grades: Highly Purified. CAS No. 93322-84-0. Pack Sizes: 25mg, 250mg. Molecular Formula: C17H15Br, Molecular Weight: 299.2. US Biological Life Sciences.
Worldwide
2,5,8,11,14,17,20-Tricosaheptayn-1-ol
2,5,8,11,14,17,20-Tricosaheptayn-1-ol is an unsaturated compound that is related to Arachidonicacid (A3303). Arachidonicacid is membrane phospholipid component of mammalian cells that is known to give the cell membranes their correct fluidity. Arachidonicacid also directly activates potassium channels in smooth muscle. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C23H20O, Molecular Weight: 312.399999999999. US Biological Life Sciences.
Worldwide
2,5,8,11,14,17-Icosahexayn-1-ol
2,5,8,11,14,17-Icosahexayn-1-ol is an unsaturated compound that is related to Arachidonicacid (A3303). Arachidonicacid is membrane phospholipid component of mammalian cells that is known to give the cell membranes their correct fluidity. Arachidonicacid also directly activates potassium channels in smooth muscle. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C20H18O, Molecular Weight: 274.36. US Biological Life Sciences.
Worldwide
2,5,8,11,14-Heptadecapentayn-1-ol
2,5,8,11,14-Heptadecapentayn-1-ol is an unsaturated compound that is related to Arachidonicacid (A3303). Arachidonicacid is membrane phospholipid component of mammalian cells that is known to give the cell membranes their correct fluidity. Arachidonicacid also directly activates potassium channels in smooth muscle. Group: Biochemicals. Grades: Highly Purified. CAS No. 93318-79-7. Pack Sizes: 25mg, 250mg. Molecular Formula: C17H16O, Molecular Weight: 236.31. US Biological Life Sciences.
Worldwide
4-Hydroxy Diclofenac Acyl Glucuronide
4-Hydroxy Diclofenac acyl glucuronide is a derivative of Diclofenac. Diclofenac is the first non-steroidal anti-inflammatory drug (NSAID) that is derived from phenylacetic acid. Diclofenac, like other NSAIDs, primarily works by targeting the cyclo-oxygenase pathway in the arachidonicacid cascade, reducing the formation of inflammation mediators in the body. Grades: 98%. Molecular formula: C20H19Cl2NO9. Mole weight: 488.27.
(±)5(6)-EET
5(6)-EET is a fully racemic version of the enantiomeric forms biosynthesized from arachidonicacid by cytochrome P450 enzymes. Synonyms: (±)5,6-EpETrE. Grades: ≥95% (mixture of free acid and lactone). CAS No. 87173-80-6. Molecular formula: C20H32O3. Mole weight: 320.5.
5,6-Epoxyeicosatrienoic acid
5,6-Epoxyeicosatrienoic acid (5,6-EET; (±)5,6-EpETrE) is a fully racemic version of the enantiomeric forms biosynthesized from arachidonicacid by cytochrome P450 enzymes. In solution, 5,6-Epoxyeicosatrienoic acid degrades into 5,6-DiHET and 5,6-δ-lactone, which can be converted to 5,6-DiHET and quantified by GC-MS. In neuroendocrine cells, such as the anterior pituitary and pancreatic islets, 5,6-Epoxyeicosatrienoic acid has been implicated in the mobilization of calcium and hormone secretion. 5,6-Epoxyeicosatrienoic acid is an inhibitor of T-type voltage-gated calcium channels (Cav3) that inhibits isoforms Cav3.1, Cav3.2 ( IC 50 =0.54 μM), and Cav3. and decreases nifedipine-resistant phenylephrine-induced vasoconstriction in isolated mouse mesenteric arteries via Cav3.2 blockade when used at a concentration of 3 μM. In addition, it is a substrate of COX-1 and COX-2. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 5,6-EET; (±)5,6-EpETrE. CAS No. 87173-80-6. Pack Sizes: 25 μg (312.04 μM * 250 μL in Ethanol); 50 μg (312.04 μM * 500 μL in Ethanol); 100 μg (312.04 μM * 1 mL in Ethanol). Product ID: HY-132184.
5(S)?-?HPETE
5(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid ( PUFA ) produced by the action of 5-LO on arachidonicacid. 5(S)-HpETE is metabolized to leukotriene A4 (LTA4), a key intermediate in the formation of LTs. Uses: Scientific research. Group: Natural products. CAS No. 71774-08-8. Pack Sizes: 25 μg (297.20 μM * 250 μL in Ethanol). Product ID: HY-125770.
6-ROX is a selective fluorescent probe and potential inhibitor of COX-2. 6-ROX binds to the active site of COX-2 and inhibits its conversion of arachidonicacid into prostaglandins. 6-ROX is often used in the field of optical imaging related to tumors and inflammation, and helps detect diseased tissues with high expression of COX-2 [1] [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: 6-Carboxy-X-rhodamine. CAS No. 194785-18-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-D0053.
8,11,14-Eicosatriynoic acid
8,11,14-Eicosatriynoic acid is an inhibitor of prostaglandin and leukotriene biosynthesis as well as arachidonicacid induced platelet aggregation. Synonyms: 8,11,14-ETI; Eicosa-8,11,14-triynoic acid. Grades: ≥98%. CAS No. 34262-64-1. Molecular formula: C20H28O2. Mole weight: 300.4.
8,11-Eicosadiynoic acid
8,11-Eicosadiynoic acid is an acetylenic fatty acid which inhibits arachidonicacid metabolism at several unrelated stages. 8,11-Eicosadiynoic acid inhibits the enzymes, arachidonoyl synthase, acyl-CoA synthase, Δ-5-desaturase, COX, and also arachidonicacid uptake by platelets. Synonyms: EDYA; Eicosa-8,11-diynoic acid. Grades: ≥95%. CAS No. 82073-91-4. Molecular formula: C20H32O2. Mole weight: 304.5.
(±)8(9)-EET
(±)8(9)-EET is a fully racemic version of the R/S enantiomeric forms biosynthesized from arachidonicacid. (±)8(9)-EET is a major cytochrome P450 (CYP450) metabolite in the renal cortex. Synonyms: (±)8,9-EpETrE; (±)8,9-epoxy-5Z,11Z,14Z-eicosatrienoic acid; 8S,9R-epoxy-5Z,11Z,14Z-eicosatrienoic acid; (Z)-7-[(2S,3R)-3-[(2Z,5Z)-undeca-2,5-dienyl]oxiran-2-yl]hept-5-enoic acid. Grades: ≥98%. Molecular formula: C20H32O3. Mole weight: 320.5.
8-Isoprostaglandin F2α
8-Isoprostaglandin F2α is an isoprostane produced by the non-enzymatic peroxidation of arachidonicacid in membrane phospholipids. 8-Isoprostaglandin F2α is present in human plasma in two distinct forms - esterified in phospholipids and as the free acid. 8-Isoprostaglandin F2α is a weak TP receptor agonist in vascular smooth muscle. Uses: Scientific research. Group: Natural products. CAS No. 27415-26-5. Pack Sizes: 500 μg; 1 mg. Product ID: HY-113209.
AACOCF
AACOCF, an anlogue of arachidonicacid, is a slow-binding inhibitor of cytosolic (85 kDa) phospholipase A2. It also inhibits fatty acid amide hydrolase (FAAH, anandamide amidase) in vitro. Synonyms: 1,1,1-Trifluoro-6Z,9Z,12Z,15Z-heneicosateraen-2-one; Arachidonyl trifluoromethyl ketone; Arachidonyltrifluoromethane. CAS No. 149301-79-1. Molecular formula: C21H31F3O. Mole weight: 356.47.
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