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Ac-Arg-Leu-Arg-AMC is a fluorogenic substrate for the determination of the trypsin-like activity of purified proteasomes (Km = 78 μM). Synonyms: Ac-RLR-AMC; N2-Acetyl-L-arginyl-L-leucyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-argininamide; L-Argininamide, N2-acetyl-L-arginyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-. Grades: ≥95%. CAS No. 929903-87-7. Molecular formula: C30H46N10O6. Mole weight: 642.76.
Ac-Gly-Ala-Val-Ile-Leu-Arg-Arg-NH2
Ac-Gly-Ala-Val-Ile-Leu-Arg-Arg-NH2, a cone-shaped amphiphilic peptide, consists of a hydrophobic tail and a large cationic head group, forming donut-like aggregates. Synonyms: Ac-GAVILRR-amide; N-Acetylglycyl-L-alanyl-L-valyl-L-isoleucyl-L-leucyl-L-arginyl-L-argininamide. Grades: ≥95%. CAS No. 1092658-86-0. Molecular formula: C36H68N14O8. Mole weight: 825.01.
Ac-Leu-Arg-AMC
Ac-Leu-Arg-AMC is a fluorogenic peptide substrate. Synonyms: L-Argininamide, N-acetyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-. Grades: ≥95%. CAS No. 929621-79-4. Molecular formula: C24H34N6O5. Mole weight: 486.56.
Ac-Lys-Gln-Leu-Arg-AFC
Ac-Lys-Gln-Leu-Arg-AFC is the optimal substrate for human Hepsin, because KQLR/VVNG corresponds to its cleavage site. Excitation at 395-400 nm, emission at 495-505 nm. Hepsin is a membrane-anchored serine protease that is overexpressed in ovarian, prostate cancer and renal cell carcinomas, and therefore can be used as a prognostic marker. Synonyms: Ac-KQLR-AFC; L-Argininamide, N2-acetyl-L-lysyl-L-glutaminyl-L-leucyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-; N2-Acetyl-L-lysyl-L-glutaminyl-L-leucyl-N-[2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl]-L-argininamide. Grades: ≥95%. CAS No. 1802078-38-1. Molecular formula: C35H51F3N10O8. Mole weight: 796.84.
Ac-Thr-Ile-Nle-psi(CH2NH)Nle-Gln-Arg-NH2
Ac-Thr-Ile-Nle-psi(CH2NH)Nle-Gln-Arg-NH2 is an HIV-1 protease inhibitor whose sequence is derived from the cleavage site of the viral gag-pol poly-protein. Electron density studies have shown that this inhibitor binds to the active site of the HIV-1 protease. Synonyms: MVT-101; N-acetyl-Thr-Ile-Nle-psi(CH2-NH)-Nle-Gln-Arg-amide; N-acetyl-threonyl-isoleucyl-norleucyl-psi(CH2-NH)-norleucyl-glutaminyl-argininamide; N-{(2S)-2-[(N-Acetyl-L-threonyl-L-isoleucyl)amino]hexyl}-L-norleucyl-L-glutaminyl-L-argininamide; L-Argininamide, N-[(2S)-2-[[(2S,3S)-2-[[(2S,3R)-2-(acetylamino)-3-hydroxy-1-oxobutyl]amino]-3-methyl-1-oxopentyl]amino]hexyl]-L-norleucyl-L-glutaminyl-. Grades: 95%. CAS No. 128657-47-6. Molecular formula: C35H67N11O8. Mole weight: 769.98.
Ac-Val-Arg-Pro-Arg-AMC
Ac-Val-Arg-Pro-Arg-AMC is a fluorogenic substrate for Arabidopsis thaliana metacaspase-9 (AtMC9) (kcat/Km = 4.6·105 M-1s-1). Synonyms: 7-[(Ac-Val-Arg-Pro-Arg-)Amino]-4-methylcoumarin; Ac-VRPR-AMC; N-Acetyl-L-valyl-L-arginyl-L-prolyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-argininamide; (S)-1-((S)-2-((S)-2-acetamido-3-methylbutanamido)-5-guanidinopentanoyl)-N-((S)-5-guanidino-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxopentan-2-yl)pyrrolidine-2-carboxamide; L-Argininamide, N-acetyl-L-valyl-L-arginyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-. Grades: ≥95%. CAS No. 919515-51-8. Molecular formula: C34H51N11O7. Mole weight: 725.85.
ALX 40-4C
ALX 40-4C is a small peptide inhibitor of the chemokine receptor CXCR4, which inhibits the binding of SDF-1 to CXCR4 and inhibits the replication of X4 strain HIV-1. It is also an APJ receptor antagonist. Synonyms: Ac-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-NH2; N-acetyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-argininamide; Ac-(D-Arg)9-NH2; ALX40-4C; N-alpha-Acetyl-nona-D-arginine amide. Grades: ≥95%. CAS No. 143413-49-4. Molecular formula: C56H113N37O10. Mole weight: 1464.74.
ALX 40-4C Trifluoroacetate
ALX 40-4C Trifluoroacetate is a small peptide inhibitor of the chemokine receptor CXCR4, which inhibits the binding of SDF-1 to CXCR4 and inhibits the replication of X4 strain HIV-1. It is also an APJ receptor antagonist. Synonyms: Ac-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-NH2.TFA; N-acetyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-argininamide trifluoroacetic acid; ALX 40-4C TFA. Grades: >98%. Molecular formula: C56H113N37O10.C2HF3O2. Mole weight: 1578.76.
Anthranilyl-HIV Protease Substrate
Anthranilyl-HIV Protease Substrate is a hexapeptide FRET substrate derived from the p24/p15 cleavage site of the gag-pol polyprotein of the virus (excitation at 280 nm, emission at >435 nm). Synonyms: Abz-TI-Nle-F(4-NO2)-QR-NH2; (2-aminobenzoyl)-L-threonyl-L-isoleucyl-L-norleucyl-4-nitro-L-phenylalanyl-L-glutaminyl-L-argininamide; H-2Abz-Thr-Ile-Nle-Phe(4-NO2)-Gln-Arg-NH2; L-Argininamide, N-(2-aminobenzoyl)-L-threonyl-L-isoleucyl-L-norleucyl-4-nitro-L-phenylalanyl-L-glutaminyl-. Grades: 95%. CAS No. 133233-38-2. Molecular formula: C43H65N13O11. Mole weight: 940.06.
Antileukinate
Antileukinate is a synthetic hexapeptide with an acetylated amino terminus and an amidated carboxyl terminus. Antileukinate can inhibit acute lung injury by suppressing neutrophil mobilization induced by CXC-chemokines. It inhibits IL-8 binding to neutrophils, which prevents neutrophil chemotaxis and β-glucuronidase release, and blocks IL-8-induced skin edema in rabbits. When antileukinate was added to melanoma cells, it inhibited the binding of MGSA/GRO&alpha. Synonyms: Interleukin-8 Inhibitor; N2-Acetyl-L-arginyl-L-arginyl-L-tryptophyl-L-tryptophyl-L-cysteinyl-L-argininamide; IL-8 (inhibitor). Grades: ≥95%. CAS No. 138559-60-1. Molecular formula: C45H66N18O7S. Mole weight: 1003.2.
AP 811
AP 811 has been found to be an NPR3 antagonist and could restrain Na+/K+ pump activity in rabbit ventricular cardiomyocytes. Synonyms: N2-[[4-[ (2-Naphthalenylcarbonyl) amino]phenyl]acetyl]-L-arginyl-L-isoleucyl-L-α -aspartyl-N-[ (2S) -2-methylbutyl]-L-argininamide; (S) -N2-[[4-[ (2-Naphthalenylcarbonyl) amino]phenyl]acetyl]-L-arginyl-L-isoleucyl-L-α -aspartyl-N- (2-methylbutyl) -L-argininamide; AP811; AP-811. Grades: ≥95% by HPLC. CAS No. 124833-45-0. Molecular formula: C46H66N12O8. Mole weight: 915.09.
Arg-Arg β-Naphthylamide Trihydrochloride
A specific substrate for dipeptidyl peptidase III. Synonyms: Arg-Arg beta-naphthylamide trihydrochloride; H-Arg-Arg-βNA 3 HCl; L-Argininamide,L-arginyl-N-2-naphthalenyl-, trihydrochloride (9CI). Grades: 95%. CAS No. 100900-26-3. Molecular formula: C22H36Cl3N9O2. Mole weight: 564.94.
Big Endothelin-3 (22-41) amide (human)
Synonyms: Big ET-3 (22-41) amide (human); H-Ile-Asn-Thr-Pro-Glu-Gln-Thr-Val-Pro-Tyr-Gly-Leu-Ser-Asn-Tyr-Arg-Gly-Ser-Phe-Arg-NH2; L-isoleucyl-L-asparagyl-L-threonyl-L-prolyl-L-alpha-glutamyl-L-glutaminyl-L-threonyl-L-valyl-L-prolyl-L-tyrosyl-glycyl-L-leucyl-L-seryl-L-asparagyl-L-tyrosyl-L-arginyl-glycyl-L-seryl-L-phenylalanyl-L-argininamide. Grades: ≥95%. CAS No. 174283-52-4. Molecular formula: C102H156N30O31. Mole weight: 2298.51.
Boc-Gln-Ala-Arg-7-amido-4-methylcoumarin.
Boc-Gln-Ala-Arg-7-amido-4-methylcoumarin. Group: Biochemicals. Alternative Names: N2-[ (1, 1-Dimethylethoxy) carbonyl]-L-glutaminyl-L-alanyl-N- (4-methyl-2-oxo-2H-1-benzopyran-7-yl) -L-argininamide. Grades: Highly Purified. CAS No. 113866-20-9. Pack Sizes: 5mg. Molecular Formula: C29H42N8O8, Molecular Weight: 630.69. US Biological Life Sciences.
Worldwide
Boc-Gln-Ala-Arg-pNA
Boc-Gln-Ala-Arg-pNA is a chromogenic substrate for trypsin and matriptase-2. Synonyms: Boc-QAR-pNA; L-Argininamide, N2-[(1,1-dimethylethoxy)carbonyl]-L-glutaminyl-L-alanyl-N-(4-nitrophenyl)-; N2-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-glutaminyl-L-alanyl-N-(4-nitrophenyl)-L-argininamide; N-Boc-Gln-Ala-Arg-p-nitroanilide. Grades: ≥95% by HPLC. CAS No. 1926163-47-4. Molecular formula: C25H39N9O8. Mole weight: 593.63.
BZ-ILE-GLU-GLY-ARG-PNA
Bz-IEGR-pNA is a substrate for plasma kallikrein and coagulation factor XIIa. Synonyms: Nalpha-Benzoyl-L-isoleucyl-L-glutamyl-glycyl-L-arginine-4-nitroanilide; L-Argininamide, N-benzoyl-L-isoleucyl-L-alpha-glutamylglycyl-N-(4-nitrophenyl)-. CAS No. 59068-47-2. Molecular formula: C32H43N9O9. Mole weight: 697.74.
CJC1295 Without DAC
CJC-1295 is a 30-amino acid peptide and a growth hormone releasing hormone (GHRH) analog. It prolongs stimulation of growth hormone (GH) and insulin-like growth factor I secretion. It also extends the half-life and bioavailability of growth-hormone-releasing hormone 1-29. Synonyms: CJC 1295; CJC1295; L-tyrosyl-D-alanyl-L-alpha-aspartyl-L-alanyl-L-isoleucyl-L-phenylalanyl-L-threonyl-L-glutaminyl-L-seryl-L-tyrosyl-L-arginyl-L-lysyl-L-valyl-L-leucyl-L-alanyl-L-glutaminyl-L-leucyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-isoleucyl-L-leucyl-L-seryl-L-argininamide. Grades: >98%. CAS No. 863288-34-0. Molecular formula: C152H252N44O42. Mole weight: 3367.9.
Cys(Npys)-(Arg)9
It is a peptide composed of 9 arginine residues synthesized from an activated cysteine residue C(Npys), where Npys is 3-Nitro-2-pyridinesulfenyl protective cysteine. The S(Npys) group of this cysteine-containing 9R is capable of reacting selectively with the free thiol group of another cysteine-containing peptide to form an unsymmetrical disulfide bond. Coupling of sulfhydrils has been studied as an effective means to deliver/release therapeutic agents such as siRNA in the reducing environment within the cell. Synonyms: H-Cys(Nyps)-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-NH2; S-(3-nitropyridin-2-yl)sulfanyl-L-cysteinyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-argininamide. Grades: ≥95%. CAS No. 1417221-06-7. Molecular formula: C62H118N40O12S2. Mole weight: 1679.99.
Cys(Npys)-(D-Arg)9
It is a peptide consisting of 9 D-arginine residues and one activated cysteine residue C(Npys), where Npys is 3-Nitro-2-pyridinesulfenyl group protects cysteine. This modification has been used to make the peptide suitable for conjugation and cell permeability studies as a carrier peptide. The S(Npys) group of this cysteine-containing 9R is capable of reacting selectively with the free thiol group of another cysteine-containing peptide to form an unsymmetrical disulfide bond. Synonyms: H-Cys(Npys)-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-NH2; S-(3-nitropyridin-2-yl)sulfanyl-D-cysteinyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-argininamide. Grades: ≥95%. Molecular formula: C62H118N40O12S2. Mole weight: 1679.99.
Decanoyl-Arg-Val-Arg-Lys-chloromethylketone
The inhibitor Decanoyl-Arg-Val-Arg-Lys-chloromethylketone has been used to characterize the specificity of furin-like proteases. Synonyms: L-Argininamide, N2-(1-oxodecyl)-L-arginyl-L-valyl-N-[(1S)-5-amino-1-(2-chloroacetyl)pentyl]-. CAS No. 534615-50-4. Molecular formula: C34H66ClN11O5. Mole weight: 744.41.
Des-Gly-AVP
Des-Gly-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Des-Gly-Vasopressin; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-argininamide (1->6)-disulfide; Desglycine arginine vasopressin. CAS No. 47914-57-8. Molecular formula: C44H62N14O11S2. Mole weight: 1027.19.
Etelcalcetide hydrochloride
Etelcalcetide is a calcium-sensing receptor agonist as a D-amino peptide calcimimetic for the treatment of secondary hyperparathyroidism. It can bind to and activate the CaSR (calcium-sensing receptor) in the parathyroid gland as an allosteric activator, resulting in PTH reduction and suppression. Amgen Inc. announced its submission of a New Drug Application to the FDA for etelcalcetide in Aug 2015. Synonyms: AMG-416; AMG 416; AMG416; Etelcalcetide hydrochloride; KAI-4169; KAI-4169-HCl; ONO-5163; Parsabiv; Telcalcetide; Velcalcetide; Velcalcetide hydrochloride;N-Acetyl-D-cysteinyl-D-alanyl-D-arginyl-D-arginyl-D-arginyl-D-alanyl-D-argininamide disulfide with L-cysteine hydrochloride;1262780-97-1 (free). Grades: >98%. CAS No. 1334237-71-6. Molecular formula: C38H74ClN21O10S2. Mole weight: 1084.72.
Galanin (1-13)-Bradykinin (2-9) amide
Galanin (1-13)-Bradykinin (2-9) amide is a high affinity ligand and antagonist of galanin receptor. Synonyms: M35; Galanin Receptor Ligand M35; H-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-NH2; glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparagyl-L-seryl-L-alanyl-glycyl-L-tyrosyl-L-leucyl-L-leucyl-glycyl-L-prolyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-L-argininamide; M35 Peptide. Grades: ≥95%. CAS No. 142846-71-7. Molecular formula: C107H153N27O26. Mole weight: 2233.52.
H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA is the chromogenic substrate for Pin1, an important and conserved mitotic peptidyl-prolyl isomerase (PPIase) that specifically recognizes the phosphoserine-proline bonds present in mitotic phosphoproteins (kcat/Km = 20160 mM-1s-1). Synonyms: L-Argininamide, L-tryptophyl-L-phenylalanyl-L-tyrosyl-O-phosphono-L-seryl-L-prolyl-N-(4-nitrophenyl)-; L-Tryptophyl-L-phenylalanyl-L-tyrosyl-O-phosphono-L-seryl-L-prolyl-N-(4-nitrophenyl)-L-argininamide; WFY(p)SPR-pNA. CAS No. 202739-41-1. Molecular formula: C49H59N12O13P. Mole weight: 1055.05.
H-Tyr-Ile-Gly-Ser-Arg-NH2
H-Tyr-Ile-Gly-Ser-Arg-NH2 binds to laminin receptor and inhibits experimental metastasis formation. Compared with YIGSR, C-terminal amidation significantly increases peptide activity. Synonyms: YIGSR amide; H-YIGSR-NH2; L-Argininamide, L-tyrosyl-L-isoleucylglycyl-L-seryl-; L-tyrosyl-L-isoleucyl-glycyl-L-seryl-L-argininamide; L-Tyrosyl-L-isoleucylglycyl-L-seryl-N5-(diaminomethylene)-L-ornithinamide. Grades: 95%. CAS No. 110590-65-3. Molecular formula: C26H43N9O7. Mole weight: 593.68.
Indolicidin
Indolicidin is the smallest of the naturally known occurring linear antimicrobial peptides, containing the highest percentage of tryptophan of any known protein, and consists of only six different amino acids. Indolicidin has been shown to be a fairly potent antimicrobial peptide with activity against a variety of microorganisms, fungi, and protozoa. Uses: Anti-infective agents. Synonyms: cationic antimicrobial peptide; H-Ile-Leu-Pro-Trp-Lys-Trp-Pro-Trp-Trp-Pro-Trp-Arg-Arg-NH2; L-isoleucyl-L-leucyl-L-prolyl-L-tryptophyl-L-lysyl-L-tryptophyl-L-prolyl-L-tryptophyl-L-tryptophyl-L-prolyl-L-tryptophyl-L-arginyl-L-argininamide. Grades: >98%. CAS No. 140896-21-5. Molecular formula: C100H132N26O13. Mole weight: 1906.28.
LF 11 is a peptide based on the lipopolysaccharide-binding region of human lactoferricin. It shows antimicrobial activity against gram-negative and gram-positive bacteria. Synonyms: LF 11; LF11; LF-11; L-phenylalanyl-L-glutaminyl-L-tryptophyl-L-glutaminyl-L-arginyl-L-asparagyl-L-isoleucyl-L-arginyl-L-lysyl-L-valyl-L-argininamide. Grades: ≥97% by HPLC. CAS No. 832729-13-2. Molecular formula: C69H112N26O14. Mole weight: 1529.81.
Locustatachykinin I
Insect tachykinin-related peptide (TRP) isolated from Locusta migratoria. Exhibits sequence homology with vertebrate tachykinins. Synonyms: Glycyl-L-prolyl-L-serylglycyl-L-phenylalanyl-L-tyrosylglycyl-L-valyl-L-argininamide; Lom-TK I; Lom-Tachykinin-1. Grades: ≥98% by HPLC. CAS No. 126985-97-5. Molecular formula: C43H63N13O11. Mole weight: 938.05.
MAIT 203
MAIT 203 inhibits interaction of APC and Asef (RhoGEF4). It also inhibits colorectal cancer cell migration and invasion in vitro. Synonyms: MAIT 203; MAIT203; MAIT-203; N- [ (Benzyl oxy) carbonyl ] -L-alanyl glycyl -L- α -glutamyl -L-alanyl -3-cyclopentyl -L-alanyl -L-tyrosyl -L- α -glutamyl glycyl glycyl glycyl glycyl glycyl -L-arginyl -L-lysyl -L-lysyl -L-arginyl -L-arginyl -L-glutaminyl -L-arginyl -L-arginyl -L-argininamide. Molecular formula: C106H177N43O29. Mole weight: 2517.83.
Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys(Dnp)-D-Arg-NH2, a FRET substrate for cathepsin D and E, is also cleaved by napsin A. Synonyms: MOCAc-GKPILFFRL-{Lys(Dnp)}-{D-Arg}-NH2; Mca-GKPILFFRL-Dpa-r-amide; MOCAc-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-{Lys(Dnp)}-{D-Arg}-NH2; N-[(7-Methoxy-2-oxo-2H-chromen-4-yl)acetyl]glycyl-L-lysyl-L-prolyl-L-isoleucyl-L-leucyl-L-phenylalanyl-L-phenylalanyl-L-arginyl-L-leucyl-N6-(2,4-dinitrophenyl)-L-lysyl-D-argininamide; D-Argininamide, N-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]glycyl-L-lysyl-L-prolyl-L-isoleucyl-L-leucyl-L-phenylalanyl-L-phenylalanyl-L-arginyl-L-leucyl-N6-(2,4-dinitrophenyl)-L-lysyl-; Cathepsin D and E FRET Substrate. Grades: ≥90%. CAS No. 839730-93-7. Molecular formula: C85H122N22O19. Mole weight: 1756.01.
Nα-Acetyl-L-arginine amide acetate salt
N-Acetyl-L-arginine Amide is used in the study of a hydrophobic parameter for the side chain of the amino acids. Synonyms: Ac-L-Arg-NH2 Acetate; NALPHA-Acetyl-L-argininamide dihydrochloride; AC-ARG-NH2 HCl; ACETYL-L-ARGININE AMIDE HYDROCHLORIDE; N-Acetyl-L-arginine AMide Hydrochloride. Grades: ≥ 98% (TLC). CAS No. 88530-28-3. Molecular formula: C8H17N5O2. Mole weight: 215.30.
Nα-Benzoyl-L-arginine amide hydrochloride
A substrate for cathepsin and competitive inhibitor of human urokinase. Synonyms: Bz-L-Arg-NH2 HCl; (S)-N-(1-Amino-5-guanidino-1-oxopentan-2-yl)benzamide hydrochloride; N-ALPHA-BENZOYL-L-ARGININAMIDE HYDROCHLORIDE; N-α-BENZOYL-L-ARGININAMIDE HYDROCHLORIDE; Nα-Benzoyl-L-argininamide Hydrochloride Monohydrate. Grades: ≥ 99% (TLC). CAS No. 4299-03-0. Molecular formula: C13H19N5O2·HCl. Mole weight: 313.80.
PAMP-12 (human, porcine) acetate
PAMP-12(human, porcine) acetate, a major component of ir-PAMP, is an endogenous peptide agonist of Mas-related GPR X2 (MRGPRX2). Synonyms: H-Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg-NH2.CH3CO2H; L-phenylalanyl-L-arginyl-L-lysyl-L-lysyl-L-tryptophyl-L-asparagyl-L-lysyl-L-tryptophyl-L-alanyl-L-leucyl-L-seryl-L-argininamide acetic acid; 9-20-Proadrenomedullin (pig) acetate; Human PAMP(9-20) acetate; Human PAMP-12 acetate; PAMP 9-20 acetate; Porcine PAMP 12 acetate; Porcine PAMP(9-20) acetate. Grades: ≥95%. Molecular formula: C79H123N25O16. Mole weight: 1678.98.
PAMP-20 (human)
PAMP-20 is an endogenous peptide agonist of Mas related GPR X2 (MRGPRX2). Synonyms: Proadrenomedullin (1-20), human; H-Ala-Arg-Leu-Asp-Val-Ala-Ser-Glu-Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg-NH2; L-alanyl-L-arginyl-L-leucyl-L-alpha-aspartyl-L-valyl-L-alanyl-L-seryl-L-alpha-glutamyl-L-phenylalanyl-L-arginyl-L-lysyl-L-lysyl-L-tryptophyl-L-asparagyl-L-lysyl-L-tryptophyl-L-alanyl-L-leucyl-L-seryl-L-argininamide. Grades: ≥95%. CAS No. 150238-87-2. Molecular formula: C112H178N36O27. Mole weight: 2460.84.
Penetratin-Arg
Penetratin-Arg, a cell-penetrating peptide (CPP) derived from the 3rd helix of Drosophila Antennapedia homeodomain protein, can permeate cell membrane at low micromolar concentration without significantly affecting membrane. It contains a nuclear localization sequence that facilitates internalization of cargo into living cells. Synonyms: PenArg; H-Arg-Gln-Ile-Arg-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Arg-Trp-Arg-Arg-NH2; L-arginyl-L-glutaminyl-L-isoleucyl-L-arginyl-L-isoleucyl-L-tryptophyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-arginyl-L-arginyl-L-methionyl-L-arginyl-L-tryptophyl-L-arginyl-L-argininamide. Grades: >98%. Molecular formula: C104H169N43O19S. Mole weight: 2357.80.
pGlu-Pro-Arg-MNA is a peptide compound that has potential biology activity in many areas. Uses: Pglu-pro-arg-mna is a peptide compound that has potential biology activity in many areas. Synonyms: pGlu-PR-MNA; L-Argininamide, 5-oxo-L-prolyl-L-prolyl-N-(2-methoxy-4-nitrophenyl)-. Grades: 98%. CAS No. 130835-45-9. Molecular formula: C23H32N8O7. Mole weight: 532.55.
Proadrenomedullin (1-20) (rat)
Synonyms: PAMP (rat); H-Ala-Arg-Leu-Asp-Thr-Ser-Ser-Gln-Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg-NH2; L-Alanyl-L-arginyl-L-leucyl-L-α-aspartyl-L-threonyl-L-seryl-L-seryl-L-glutaminyl-L-phenylalanyl-L-arginyl-L-lysyl-L-lysyl-L-tryptophyl-L-asparaginyl-L-lysyl-L-tryptophyl-L-alanyl-L-leucyl-L-seryl-L-argininamide. Grades: ≥95% by HPLC. CAS No. 167699-60-7. Molecular formula: C111H177N37O28. Mole weight: 2477.82.
Protegrin-1
Protegrin-1 is an antimicrobial peptide found in Sus scrofa (Pig), and has antibacterial activity against gram-negative bacteria Escherichia coli (MIC=64 μg/ml) and gram-positive bacteria Staphylococcus aureus (MIC=64 μg/ml), Staphylococcus epidermidis (MIC=2 μg/ml), and has antiviral activity. Synonyms: PG-1; H-Arg-Gly-Gly-Arg-Leu-Cys(1)-Tyr-Cys(2)-Arg-Arg-Arg-Phe-Cys(2)-Val-Cys(1)-Val-Gly-Arg-NH2; L-arginyl-glycyl-glycyl-L-arginyl-L-leucyl-L-cysteinyl-L-tyrosyl-L-cysteinyl-L-arginyl-L-arginyl-L-arginyl-L-phenylalanyl-L-cysteinyl-L-valyl-L-cysteinyl-L-valyl-glycyl-L-argininamide (6->15),(8->13)-bis(disulfide); L-Arginylglycylglycyl-L-arginyl-N-[(1R, 4S, 7R, 12R, 15S, 18R, 21S, 24S, 27S, 30S)-12-({(2S)-1-[(2-{[(2S)-1-amino-5-carbamimidamido-1-oxo-2-pentanyl]amino}-2-oxoethyl)amino]-3-methyl-1-oxo-2-butanyl}carbamoyl)-21-benzyl-24, 27, 30-tris(3-carbamimidamidopropyl)-4-(4-hydroxybenzyl)-15-isopropyl-3, 6, 14, 17, 20, 23, 26, 29, 32-nonaoxo-9, 10, 34, 35-tetrathia-2, 5, 13, 16, 19, 22, 25, 28, 31-nonaazabicyclo[16.14.4]hexatriacont-7-yl]-L-leucinamide; NPG1; Neutrophil peptide 1. Grades: >85%. Molecular formula: C88H147N37O19S4. Mole weight: 2155.62.
Protegrin-3
Protegrin-3 is an antimicrobial peptide found in Sus scrofa (Pig), and has antibacterial, antiviral and antifungal activity. Synonyms: PG-3; H-Arg-Gly-Gly-Gly-Leu-Cys(1)-Tyr-Cys(2)-Arg-Arg-Arg-Phe-Cys(2)-Val-Cys(1)-Val-Gly-Arg-NH2; L-arginyl-glycyl-glycyl-glycyl-L-leucyl-L-cysteinyl-L-tyrosyl-L-cysteinyl-L-arginyl-L-arginyl-L-arginyl-L-phenylalanyl-L-cysteinyl-L-valyl-L-cysteinyl-L-valyl-glycyl-L-argininamide (6->15),(8->13)-bis(disulfide); NPG3; Neutrophil peptide 3. Grades: >85%. Molecular formula: C84H138N34O19S4. Mole weight: 2056.47.
Protegrin-4
Protegrin-4 is an antimicrobial peptide found in Sus scrofa (Pig), and has antimicrobial activity. Synonyms: PG-4; H-Arg-Gly-Gly-Arg-Leu-Cys(1)-Tyr-Cys(2)-Arg-Gly-Trp-Ile-Cys(2)-Phe-Cys(1)-Val-Gly-Arg-NH2; L-arginyl-glycyl-glycyl-L-arginyl-L-leucyl-L-cysteinyl-L-tyrosyl-L-cysteinyl-L-arginyl-glycyl-L-tryptophyl-L-isoleucyl-L-cysteinyl-L-phenylalanyl-L-cysteinyl-L-valyl-glycyl-L-argininamide (6->15),(8->13)-bis(disulfide); NPG4; Neutrophil peptide 4. Grades: >85%. CAS No. 157214-61-4. Molecular formula: C90H138N32O19S4. Mole weight: 2100.54.
Protegrin-5
Protegrin-5 is an antimicrobial peptide found in Sus scrofa (Pig), and has antimicrobial activity. Synonyms: PG-5; H-Arg-Gly-Gly-Arg-Leu-Cys(1)-Tyr-Cys(2)-Arg-Pro-Arg-Phe-Cys(2)-Val-Cys(1)-Val-Gly-Arg-NH2; L-arginyl-glycyl-glycyl-L-arginyl-L-leucyl-L-cysteinyl-L-tyrosyl-L-cysteinyl-L-arginyl-L-prolyl-L-arginyl-L-phenylalanyl-L-cysteinyl-L-valyl-L-cysteinyl-L-valyl-glycyl-L-argininamide (6->15),(8->13)-bis(disulfide); PG-5 protegrin; protegrin PG-5; NPG5; Neutrophil peptide 5. Grades: >85%. Molecular formula: C87H142N34O19S4. Mole weight: 2096.53.
Serine substitution of alanine significantly improves the plasma stability of GLP-1(7-36) amide to DPP IV, but does not affect its insulinotropic activity. This may indicate that the modification can improve the potential of GLP-1 in the treatment of type 2 diabetes. Synonyms: (Ser79)-Proglucagon (78-107) amide (human, bovine, guinea pig, mouse, rat); H-His-Ser-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2; L-Histidyl-L-seryl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysylglycyl-L-argininamide; (Ser8)-Glucagon-Like Peptide 1 (7-36) amide; 8-L-Serine-36-L-argininamide-7-36-glucagon-like peptide I (human). Grades: 95%. CAS No. 215777-46-1. Molecular formula: C149H226N40O46. Mole weight: 3313.68.
Sermorelin
This polypeptide is a growth hormone-releasing hormone (GHRH) analogue which is made up of 29 amino acids. Sermorelin is recognized as the shortest fully functional fragment of GHRH. It is used as a diagnostic agent to assess growth hormone (GH) secretion. Meanwhile, it is also used as doping agent in sports due to its correlation with increased growth of muscular and skeletal tissue. Synonyms: 1-29-Somatoliberin (human pancreatic islet), 29-L-argininamide-; 1-29-Human GH-RH-NH2; 1-29-Human GRF-NH2; [1-29]-Human somatoliberin-NH2; Geref; Groliberin; Groliberin R; hGH-RH-(1-29)-NH2; Human growth hormone-releasing factor(1-29) amide; Human growth hormone-releasing hormone(1-29) amide; Human pancreatic somatoliberin(1-29) amide; Human somatoliberin-(1-29) amide; Porcine growth hormone-releasing factor(1-29)-NH2; GRF (1-29) amide (human); GHRF (1-29), amide, human; H-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2. Grades: 95%. CAS No. 86168-78-7. Molecular formula: C149H246N44O42S. Mole weight: 3357.88.
Sermorelin acetate
Sermorelin acetate is a growth hormone-releasing hormone (GHRH) analogue composed of 29 amino acids. It is recognized as the shortest fully functional fragment of GHRH. It is used as a diagnostic agent to assess growth hormone (GH) secretion. Meanwhile, it is also used as a doping agent in sports due to its correlation with increased growth of muscular and skeletal tissue. Synonyms: 1-29-Somatoliberin (human pancreatic islet), 29-L-argininamide-, acetate (1:x); H-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2.CH3CO2H; L-tyrosyl-L-alanyl-L-alpha-aspartyl-L-alanyl-L-isoleucyl-L-phenylalanyl-L-threonyl-L-asparagyl-L-seryl-L-tyrosyl-L-arginyl-L-lysyl-L-valyl-L-leucyl-glycyl-L-glutaminyl-L-leucyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-isoleucyl-L-methionyl-L-seryl-L-argininamide acetic acid. Grades: ≥95%. CAS No. 516482-86-3. Molecular formula: C149H246N44O42S.xC2H4O2. Mole weight: 3357.88 (free base).
Taspoglutide
Taspoglutide is a long-acting glucagon-like peptide 1 (GLP-1) receptor agonist (EC50 = 0.06 nM) under investigation for treatment of type 2 diabetes. Synonyms: (N-((N-(L-histidyl)-2-aminoisobutyryl)-L-alpha-glutamyl-glycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-alpha-glutamyl-glycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysyl)-2-aminoisobutyryl)-L-argininamide; H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Aib-Arg-NH2. CAS No. 275371-94-3. Molecular formula: C152H232N40O45. Mole weight: 3339.71.
TFLLR-NH2, derived from the protease-activated receptor-1 (PAR1), is a selective PAR1 agonist with an EC50 of 1.9 μM. Synonyms: TFLLR amide; (Thr1)-TRAP-5 amide; (Thr1)-PAR-1 (1-5) amide (human); PAR-1-activating peptide; PAR-1-AP; L-threonyl-L-phenylalanyl-L-leucyl-L-leucyl-L-argininamide. Grades: 98%. CAS No. 197794-83-5. Molecular formula: C31H53N9O6. Mole weight: 647.81.
TFLLR-NH2 2TFA
TFLLR-NH2 2TFA, derived from the protease-activated receptor-1 (PAR1), is a selective PAR1 agonist with an EC50 of 1.9 μM. Synonyms: H-Thr-Phe-Leu-Leu-Arg-NH2.2TFA; TFLLR-NH2.2TFA; L-threonyl-L-phenylalanyl-L-leucyl-L-leucyl-L-argininamide trifluoroacetic acid; PAR-1-AP trifluoroacetate; Protease-activated receptor-1-activating peptide trifluoroacetate. Grades: ≥95%. Molecular formula: C31H53N9O6.2C2HF3O2. Mole weight: 875.87.
TFLLR-NH2(TFA)
TFLLR-NH2, derived from the protease-activated receptor-1 (PAR1), is a selective PAR1 agonist with an EC50 of 1.9 μM. Synonyms: TFLLR-NH2 trifluoroacetate salt; L-threonyl-L-phenylalanyl-L-leucyl-L-leucyl-L-argininamide trifluoroacetic acid. Grades: 99%. CAS No. 1313730-19-6. Molecular formula: C33H54F3N9O8. Mole weight: 761.83.
T-Peptide
T-peptide, a highly neurotoxic cell-permeable analog of PHF6, can be used in the study of human immunodeficiency virus (HIV) infection. T-peptide can induce Tau peptide aggregation, prevent cellular immunosuppression, improve the survival rate of sepsis mice, and inhibit the growth of residual tumor cells after surgical resection. Synonyms: PHF6-R9; L-Argininamide, N-acetyl-D-valyl-D-glutaminyl-D-isoleucyl-D-valyl-D-tyrosyl-D-lysyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-; Ac-D-Val-D-Gln-D-Ile-D-Val-D-Tyr-D-Lys-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-NH2; N-acetyl-D-valyl-D-glutaminyl-D-isoleucyl-D-valyl-D-tyrosyl-D-lysyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-argininamide. Grades: ≥95%. CAS No. 2022956-62-1. Molecular formula: C92H171N45O18. Mole weight: 2195.66.
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